CN113714094A - Preparation equipment and preparation process of caffeic acid sustained-release composition - Google Patents
Preparation equipment and preparation process of caffeic acid sustained-release composition Download PDFInfo
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- CN113714094A CN113714094A CN202111037755.5A CN202111037755A CN113714094A CN 113714094 A CN113714094 A CN 113714094A CN 202111037755 A CN202111037755 A CN 202111037755A CN 113714094 A CN113714094 A CN 113714094A
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- caffeic acid
- main body
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- acid composition
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/28—Moving screens not otherwise provided for, e.g. swinging, reciprocating, rocking, tilting or wobbling screens
- B07B1/34—Moving screens not otherwise provided for, e.g. swinging, reciprocating, rocking, tilting or wobbling screens jigging or moving to-and-fro perpendicularly or approximately perpendiculary to the plane of the screen
- B07B1/343—Moving screens not otherwise provided for, e.g. swinging, reciprocating, rocking, tilting or wobbling screens jigging or moving to-and-fro perpendicularly or approximately perpendiculary to the plane of the screen with mechanical drive elements other than electromagnets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C4/00—Crushing or disintegrating by roller mills
- B02C4/10—Crushing or disintegrating by roller mills with a roller co-operating with a stationary member
- B02C4/12—Crushing or disintegrating by roller mills with a roller co-operating with a stationary member in the form of a plate
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/42—Drive mechanisms, regulating or controlling devices, or balancing devices, specially adapted for screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/46—Constructional details of screens in general; Cleaning or heating of screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F15/00—Suppression of vibrations in systems; Means or arrangements for avoiding or reducing out-of-balance forces, e.g. due to motion
- F16F15/02—Suppression of vibrations of non-rotating, e.g. reciprocating systems; Suppression of vibrations of rotating systems by use of members not moving with the rotating systems
- F16F15/04—Suppression of vibrations of non-rotating, e.g. reciprocating systems; Suppression of vibrations of rotating systems by use of members not moving with the rotating systems using elastic means
- F16F15/08—Suppression of vibrations of non-rotating, e.g. reciprocating systems; Suppression of vibrations of rotating systems by use of members not moving with the rotating systems using elastic means with rubber springs ; with springs made of rubber and metal
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Aviation & Aerospace Engineering (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to the technical field of preparation of caffeic acid sustained-release compositions, in particular to preparation equipment and a preparation process of a caffeic acid sustained-release composition, wherein the preparation equipment comprises a main body, the main body is connected with a whole grain structure and a blanking structure, the whole grain structure is connected with a limiting structure, the main body is provided with a rolling structure and a collecting structure, the main body is connected with a collecting structure and a supporting structure, and the main body is connected with a dispersing structure; be convenient for carry out whole grain through whole grain structure and sieve, make the granule dispersion of bonding, be convenient for control the speed and the degree of consistency of unloading through blanking structure, be convenient for change whole grain structure subassembly through limit structure, can make the adhesion dry caffeic acid composition softwood granule together carry out the breakage and sieve through rolling the structure, can make the dry caffeic acid composition softwood granule after sieving to collect the processing through collecting structure and dispersed structure, can support the main part through bearing structure, and play certain cushioning effect.
Description
Technical Field
The invention relates to the technical field of preparation of a caffeic acid sustained-release composition, in particular to a preparation device and a preparation process of the caffeic acid sustained-release composition.
Background
Caffeic acid, obtain yellow crystal from concentrated aqueous solution, obtain monohydrate from dilute aqueous solution, slightly dissolve in cold water, it is easy to dissolve in hot water and cold ethanol, have effects such as bacteriostatic, anti-snake venom more, the slow-release composition of caffeic acid can prepare the medicament variety more, in the preparation process of tablet to slow-release composition of caffeic acid, need through mixing, make soft mass, granulate and tabletting, etc., make the soft mass of slow-release composition of caffeic acid into granule through the granulator, need to carry on the granule to the soft mass granule of composition of caffeic acid after drying and sift.
When whole grain was sieved to caffeic acid composition softwood granule after drying at present, artifical sieving efficiency is low, and the unloading was easily inhomogeneous when equipment was sieved, easily leads to the screen cloth to pile up too much, is not convenient for sieve, needs to press the manual work to sieve to the caffeic acid composition softwood granule of bonding, and is inconvenient when changing the screen cloth, and the vibration is comparatively violent.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a preparation device and a preparation process of a caffeic acid sustained-release composition.
The technical scheme adopted by the invention for solving the technical problems is as follows: a preparation device of a caffeic acid sustained-release composition comprises a main body, wherein the main body is connected with a whole grain structure and a blanking structure, the whole grain structure is connected with a limiting structure, the main body is provided with a rolling structure and a collecting structure, the main body is connected with a collecting structure and a supporting structure, and the main body is connected with a dispersing structure;
the dispersing structure comprises dispersing shafts, a plurality of dispersing shafts are rotatably connected to the main body, the dispersing shafts are fixedly connected to the inner part of the main body, dispersing plates are fixedly connected to the inner part of the main body, a plurality of driven gears are fixedly connected to one ends of the dispersing shafts penetrating through the main body, a driving disc is rotatably connected to one end of the main body, a driving gear is fixedly connected to one end of the driving disc, an auxiliary gear is rotatably connected to one end of the main body, which is far away from the driving disc, chains are wound and meshed on the driving gear, the driven gears are distributed on two sides of the chains in two groups, a plurality of auxiliary rods are rotatably connected to the main body, the auxiliary rods are distributed on one sides of the two groups of driven gears respectively and are abutted against one ends of the chains, a second belt is wound on the driving disc, and a protection plate is detachably connected to one side of the main body, which is located on the chains, through bolts, the driving disc is connected with the whole grain structure through a second belt.
The utility model discloses a shaking table, whole grain structure is including shaking the board, the inside of main part rotates and is connected with the shaking board, the bottom fixedly connected with fixed block of shaking the board, be equipped with the shake groove on the fixed block, the main part through connection has the shake axle, the shake axle cup joint with the shake groove and with shake groove sliding fit, the motor is installed to the main part, the motor runs through and has first belt through the carousel winding in the main part end with the shake axle run through in the main part end, the screen cloth has been cup jointed to the shaking board, the collection box has been cup jointed to the one end of shaking the board, the shake axle is the eccentric shaft, the eccentric end and the shake groove of shake axle cup joint and sliding fit, the one end of screen cloth is equipped with the recess, the notch end and the shake board joint of screen cloth, the shake board is the slope form.
Specifically, blanking structure includes feed bin down, feed bin under the top fixedly connected with of main part, feed bin bottom slip embedding has the separation blade down, the separation blade bottom is rotated and is connected with out the flitch, it is connected with the connecting rod with the rotation of shake board one end top to go out the flitch, the shake axis passes through carousel and second belt winding and connects, the bottom of feed bin is the quadrangular terrace form down, the top of feed bin is the quadrangular terrace down.
Specifically, the structure of rolling includes the axis of rotation, the equal fixedly connected with axis of rotation in one end both sides of main part, the main part rotates respectively through a pair of axis of rotation and is connected with the bracing piece, the one end threaded connection of axis of rotation has the nut, the one end and the bracing piece of nut are contradicted, and are a pair of the bottom of bracing piece is rotated and is connected with the pinch roller, it is connected with the extension spring to rotate between bracing piece and the main part.
Specifically, collect the structure and include the drawer, main part sliding connection has the drawer, drawer one end is equipped with the draw-in groove, the main part is close to in drawer one end sliding connection has the bayonet lock, the first spring of fixedly connected with between bayonet lock and the main part, bayonet lock and draw-in groove are contradicted.
Specifically, bearing structure includes the support column, the bottom sliding connection of main part has two sets of support columns, support column bottom fixedly connected with rubber pad, it has the second spring to contradict between support column and the main part.
Specifically, limit structure includes the stopper, the one end sliding connection who shakes the board has the stopper, shake board fixedly connected with slide bar, the stopper passes through the slide bar and shakes board sliding connection, shake the board and rotate and be connected with the lead screw, lead screw and stopper threaded connection, stopper one end and screen cloth are contradicted, the stopper is "L" shape, the one end fixedly connected with knob of lead screw.
Specifically, the preparation process of the preparation equipment of the caffeic acid sustained-release composition comprises the following steps:
s1: firstly, preparing the caffeic acid slow-release composition into soft materials, then preparing the soft materials into granules by a granulator, sieving the dried caffeic acid composition soft materials by granule straightening, after equipment is started, putting the dried caffeic acid composition soft materials into a blanking structure, wherein the blanking structure can control blanking speed and uniformity, and the situation that the whole structure receives more dried caffeic acid composition soft materials at one time and is not beneficial to granule straightening and sieving is avoided;
s2: the blanking structure enables the dried soft caffeic acid composition particles to fall onto the granulating structure, and the granulating structure is convenient for granulating and sieving the dried soft caffeic acid composition particles through shaking, so that the bonded particles are dispersed, and tabletting is convenient for later period;
s3: then the whole grain structure can crush and sieve the dry caffeic acid composition soft material particles which are adhered together through the rolling structure, the whole grain sieved caffeic acid composition soft material particles can be collected into the inside of the collection structure, the next treatment is convenient to carry out, and the dispersion structure can enable the whole grain dried caffeic acid composition soft material particles to uniformly fall into the inside of the collection structure;
s4: when preparing the caffeic acid sustained-release tablets with different sizes and masses, the components of the sieve of the whole grain structure are convenient to replace through the limiting structure, the equipment can vibrate during working, the main body can be supported through the supporting structure, and a certain shock absorption effect is achieved.
The invention has the beneficial effects that:
(1) according to the preparation equipment and the preparation process of the caffeic acid sustained-release composition, the main body is connected with the granulating structure and the blanking structure, the granulating structure is convenient for granulating and sieving soft particles of the dried caffeic acid composition, so that the bonded particles are dispersed, the tabletting is convenient for later period, the blanking structure is convenient for controlling the blanking speed and uniformity, and the problem that the granulating structure receives more soft particles of the dried caffeic acid composition at one time and is not beneficial to granulating and sieving is solved, namely: when the caffeic acid sustained-release composition is prepared (such as caffeic acid sustained-release mixture tablets), the caffeic acid sustained-release composition is made into soft material and then is made into granules by a granulator, the dried caffeic acid composition soft material granules need to be sized, the caffeic acid composition soft material granules are placed in a lower storage bin, the caffeic acid composition soft material granules in the lower storage bin drop onto a screen, a motor is started, the motor drives a shaking shaft to rotate through a first belt, the shaking shaft is an eccentric shaft and is in sliding connection with a fixed block through a shaking groove, the fixed block is fixedly connected with a shaking plate, the shaking plate is in rotating connection with a main body, so the motor drives the shaking shaft to rotate, the shaking plate is driven to shake up and down by the shaking plate, a screen is sleeved on the shaking plate, and the screen is driven to shake, so that the caffeic acid composition soft material granules dropping onto the screen are sized, the bonded soft caffeic acid composition particles can be retained on the screen, the shaken screen can shake the bonded soft caffeic acid composition particles, when the screen cannot shake, the shaking plate is inclined, so the bonded soft caffeic acid composition particles move towards the direction of the pressing wheel, further crushing is convenient through the pressing wheel, in the shaking process of the shaking plate driven by the motor, the top end of the shaking plate is rotatably connected with the connecting rod, the top end of the connecting rod is rotatably connected with the discharging plate, so in the shaking process of the shaking plate, the discharging plate is driven by the connecting rod to swing, the blocking piece is pulled, the soft caffeic acid composition particles in the discharging bin are discharged, the caffeic acid composition particles are abutted against the discharging plate, the discharging plate shakes to uniformly discharge the soft caffeic acid composition particles, the discharging speed and uniformity are convenient to control, and the phenomenon that more dry soft caffeic acid composition particles are received by the screen at one time and are not beneficial to sieving And (6) rows.
(2) According to the preparation equipment and the preparation process of the caffeic acid sustained-release composition, the whole grain structure is connected with the limiting structure, the replacement of the whole grain structure components is facilitated through the limiting structure, and when caffeic acid sustained-release tablets with different sizes and qualities are prepared, the corresponding whole grain structure components are conveniently replaced, namely: when the screen cloth needs to be changed, go lower support bar and pinch roller earlier, drive the lead screw through rotating the knob and rotate, because lead screw one end threaded connection has the stopper, the stopper passes through the slide bar and shakes board sliding connection, thereby it deviates from in the screen cloth motion to drive the stopper, thereby alright promote the screen cloth, take off the screen cloth, change new screen cloth, the antiport lead screw drives the stopper and moves to the screen cloth direction, because the stopper is "L" shape, the one end fixedly connected with knob of lead screw, so will make stopper and screen cloth conflict and not restrict the screen cloth motion.
(3) According to the preparation equipment and the preparation process of the caffeic acid slow-release composition, the main body is provided with the rolling structure and the collection structure, the main body is provided with the dispersion structure, dry caffeic acid composition soft material particles which are adhered together can be crushed and sieved through the rolling structure, the sieved dry caffeic acid composition soft material particles can be collected through the collection structure, the next tabletting can be conveniently carried out, the granulated dry caffeic acid composition soft material particles can uniformly fall into the collection structure through the dispersion structure, and the preparation equipment and the preparation process are as follows: in the shaking process of the screen, the bonded soft caffeic acid composition particles move towards the pressing wheel, the main body is rotatably connected with the pressing wheel through the bottom end of the supporting rod, the tension spring is rotatably connected between the supporting rod and the main body, so the screen pushes the supporting rod to swing, and simultaneously drives the pressing wheel to roll on the screen, when the bonded soft caffeic acid composition particles are abutted against the pressing wheel, the pressing wheel can crush the bonded soft caffeic acid composition particles to enable the bonded soft caffeic acid composition particles to pass through the screen and fall off, thereby the purpose of crushing and sieving dry soft caffeic acid composition particles which are bonded together is achieved, the nut is separated from the rotating shaft by rotating the nut, the supporting rod and the rotating shaft rotate, the supporting rod and the pressing wheel can be disassembled, thereby the screen is convenient to replace, the dry soft caffeic acid composition particles which pass through the screen can fall into the drawer, and simultaneously, under the driving of the shaking shaft, the driving disc is driven to rotate through the second belt, so that the driving gear fixedly connected with the driving disc is driven to rotate, the chain is driven to move, under the action of the auxiliary roller and the auxiliary gear, two groups of driven gears are driven to rotate, the two groups of driven gears are respectively distributed on two sides of the chain, so that the two groups of driven gears are reversely rotated, the motor is anticlockwise rotated, so that the chain is anticlockwise rotated, the two groups of driven gears are driven to mutually reversely rotate, so that two groups of dispersing shafts and a dispersing plate are driven to reversely rotate, soft material particles mostly fall into the middle of a screen under the action of a discharging plate and fall into the middle of a collecting box, accumulation can occur, the collecting box is inconvenient to pull out, the soft material particles can be dispersed into the collecting box under the action of the dispersing plate, so that the soft material particles are more uniform, the bayonet lock is pushed in a direction away from the drawer, the first spring is compressed, and the bayonet lock is separated from the clamping groove, alright pull out the drawer to take out the dry caffeic acid composition softwood granule that sieves in the drawer, push back the drawer, promote the bayonet lock and get into the draw-in groove under the effect of first spring, thereby the pulling of restriction drawer, thereby enough make the dry caffeic acid composition softwood granule after sieving through the drawer collect the processing, the going on of preforming on the next step of being convenient for.
(4) The invention relates to a preparation device and a preparation process of a caffeic acid sustained-release composition, wherein a main body is connected with a collection structure and a support structure, the main body can be supported by the support structure, and a certain shock absorption effect is achieved, namely: the bottom of main part has two sets of support columns, and support column bottom fixedly connected with rubber pad is contradicted between support column and the main part and is had the second spring, and equipment will produce in the course of the work and rock, can play certain cushioning effect under the effect of rubber pad and second spring.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a schematic structural view showing the overall structure of a preferred embodiment of an apparatus for preparing a sustained-release composition of caffeic acid provided by the present invention;
FIG. 2 is a schematic view of the connection structure of the finishing structure, the blanking structure, the rolling structure and the supporting structure shown in FIG. 1;
FIG. 3 is an enlarged view of the structure A shown in FIG. 2;
FIG. 4 is an enlarged view of the structure B shown in FIG. 2;
FIG. 5 is an enlarged view of the structure C shown in FIG. 2;
FIG. 6 is a schematic view of the structure of the position-limiting structure shown in FIG. 2;
FIG. 7 is a schematic view of the connecting structure of the body and the dispersing structure shown in FIG. 1;
fig. 8 is a flow chart of a preparation process of the preparation device of the caffeic acid sustained-release composition provided by the invention.
In the figure: 1. a main body, 2, a whole grain structure, 21, a motor, 22, a shaking shaft, 23, a first belt, 24, a screen, 25, a collection box, 26, a fixed block, 27, a shaking groove, 28, a shaking plate, 3, a blanking structure, 31, a blanking bin, 32, a baffle, 33, a discharging plate, 34, a connecting rod, 4, a rolling structure, 41, a supporting rod, 42, a pressing wheel, 43, a tension spring, 44, a nut, 45, a rotating shaft, 5, a collection structure, 51, a drawer, 52, a clamping pin, 53, a clamping groove, 54, a first spring, 6, a supporting structure, 61, a supporting column, 62, a rubber pad, 63, a second spring, 7, a limiting structure, 71, a limiting block, 72, a screw rod, 73, a sliding rod, 8, a dispersing structure, 81, a protection plate, 82, a second belt, 83, a dispersing plate, 84, a dispersing shaft, 85, a driven gear, 86, a chain, 87, a driving disk, 88 and an auxiliary gear, 89. drive gear, 89a, auxiliary roller.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1 to 7, the apparatus for preparing a sustained-release caffeic acid composition according to the present invention comprises a main body 1, wherein the main body 1 is connected with a whole grain structure 2 and a blanking structure 3, the whole grain structure 2 is connected with a limiting structure 7, the main body 1 is provided with a rolling structure 4 and a collecting structure 5, the main body 1 is connected with a collecting structure 5 and a supporting structure 6, and the main body 1 is connected with a dispersing structure 8;
the dispersing structure 8 comprises a dispersing shaft 84, a plurality of dispersing shafts 84 are connected to the main body 1 in a rotating mode, the dispersing shafts 84 are located on a dispersing plate 83 fixedly connected to the inner portion of the main body 1, the dispersing shafts 84 penetrate through a plurality of driven gears 85 fixedly connected to one end of the main body 1, one end of the main body 1 is connected with a driving plate 87 in a rotating mode, one end of the driving plate 87 is fixedly connected with a driving gear 89, one end, deviating from the driving plate 87, of the main body 1 is connected with an auxiliary gear 88 in a rotating mode, chains 86 are wound and meshed on the driving gear 89, the driven gears 85 and the auxiliary gear 88, the driven gears 85 are distributed on two sides of the chains 86 in two groups, a plurality of auxiliary rods 89a are connected to the main body 1 in a rotating mode, the auxiliary rods 89a are distributed on one side of the two groups of driven gears 85 respectively and abut against one ends of the chains 86, the driving disc 87 is wound with the second belt 82, one side of the main body 1, which is positioned on the chain 86, is detachably connected with a protection plate 81 through a bolt, and the driving disc 87 is connected with the whole grain structure 2 through the second belt 82.
Specifically, the granule adjusting mechanism 2 comprises a shaking plate 28, the shaking plate 28 is rotatably connected to the inside of the main body 1, the bottom end of the shaking plate 28 is fixedly connected with a fixed block 26, a shaking groove 27 is arranged on the fixed block 26, the main body 1 is connected with a shaking shaft 22 in a penetrating way, the shaking shaft 22 is sleeved with a shaking groove 27 and is in sliding fit with the shaking groove 27, the main body 1 is provided with a motor 21, the motor 21 penetrates through the end of the main body 1, a shaking shaft 22 penetrates through the end of the main body 1, a first belt 23 is wound on the turntable, the screen 24 is sleeved on the shaking plate 28, the collecting box 25 is sleeved on one end of the shaking plate 28, the shaking shaft 22 is an eccentric shaft, the eccentric end of the shaking shaft 22 is sleeved and matched with the shaking groove 27 in a sliding way, a groove is formed in one end of the screen 24, the groove end of the screen 24 is clamped with the shaking plate 28, and the shaking plate 28 is inclined; namely: when the caffeic acid sustained-release composition is prepared (such as caffeic acid sustained-release mixture tablets), the caffeic acid sustained-release composition is made into soft material and then made into granules by a granulator, the dried caffeic acid composition soft material granules need to be sized and sieved, the caffeic acid composition soft material granules are placed in a lower material bin 31, the caffeic acid composition soft material granules in the lower material bin 31 drop onto a screen 24, a motor 21 is started, the motor 21 drives a shaking shaft 22 to rotate through a first belt 23, the shaking shaft 22 is an eccentric shaft, the shaking shaft 22 is in sliding connection with a fixed block 26 through a shaking groove 27, the fixed block 26 is fixedly connected with a shaking plate 28, the shaking plate 28 is in rotating connection with a main body 1, the motor 21 drives the shaking shaft 22 to rotate, the shaking shaft 22 drives the shaking plate 28 to shake up and down, the screen 24 is sleeved on the shaking plate 28 to drive the screen 24 to shake, therefore, the soft caffeic acid composition particles falling on the screen 24 are sifted, the bonded soft caffeic acid composition particles will be retained on the screen 24, the shaken screen 24 can shake off the bonded soft caffeic acid composition particles, when the screen 24 can not be shaken off, the shaking plate 28 is inclined, so that the bonded soft caffeic acid composition particles move towards the pressing wheel 42, and further crushing by the pressing wheel 42 is facilitated.
Specifically, the blanking structure 3 includes a blanking bin 31, the top end of the main body 1 is fixedly connected with the blanking bin 31, a blocking piece 32 is embedded into the bottom end of the blanking bin 31 in a sliding manner, the bottom end of the blocking piece 32 is rotatably connected with a discharging plate 33, the top ends of the discharging plate 33 and one end of the shaking plate 28 are rotatably connected with a connecting rod 34, the shaking shaft 22 is wound and connected with a second belt 82 through a turntable, the bottom end of the blanking bin 31 is in a quadrangular frustum shape, and the top end of the blanking bin 31 is in a quadrangular frustum shape; namely: in the shaking process of the shaking plate 28 driven by the motor 21, the connecting rod 34 is rotatably connected to the top end of the shaking plate 28, and the top end of the connecting rod 34 is rotatably connected with the discharging plate 33, so that in the shaking process of the shaking plate 28, the discharging plate 33 is driven by the connecting rod 34 to swing, the blocking piece 32 is pulled, soft caffeic acid composition particles in the discharging bin 31 are discharged, the soft caffeic acid composition particles are abutted against the discharging plate 33, and the soft caffeic acid composition particles are uniformly discharged by shaking of the discharging plate 33, so that the discharging speed and uniformity are conveniently controlled, and the situation that more soft dry caffeic acid composition particles received by the screen 24 at one time are not beneficial to whole-particle screening is avoided.
Specifically, the rolling structure 4 comprises a rotating shaft 45, both sides of one end of the main body 1 are fixedly connected with the rotating shaft 45, the main body 1 is respectively and rotatably connected with a support rod 41 through a pair of rotating shafts 45, one end of each rotating shaft 45 is in threaded connection with a nut 44, one end of each nut 44 is in contact with the corresponding support rod 41, the bottom ends of the support rods 41 are rotatably connected with press wheels 42, and tension springs 43 are rotatably connected between the support rods 41 and the main body 1; namely: in the shaking process of the screen 24, the bonded soft caffeic acid composition particles move towards the pressing wheel 42, the main body 1 is rotatably connected with the pressing wheel 42 through the bottom end of the supporting rod 41, the tension spring 43 is rotatably connected between the supporting rod 41 and the main body 1, so the screen 24 pushes the supporting rod 41 to swing, and simultaneously drives the pressing wheel 42 to roll on the screen 24, when the bonded soft caffeic acid composition particles are abutted against the pressing wheel 42, the pressing wheel 42 can crush the bonded soft caffeic acid composition particles to enable the bonded soft caffeic acid composition particles to pass through the screen 24 and fall, and therefore the purpose of crushing and sieving dry soft caffeic acid composition particles which are bonded together is achieved, the nut 44 is separated from the rotating shaft 45 by rotating the nut 44, the supporting rod 41 and the rotating shaft 45 rotate, the supporting rod 41 and the pressing wheel 42 can be detached, and the screen 24 is convenient to replace.
Specifically, the collecting structure 5 comprises a drawer 51, the drawer 51 is slidably connected to the main body 1, a clamping groove 53 is formed in one end of the drawer 51, a clamping pin 52 is slidably connected to one end, close to the drawer 51, of the main body 1, a first spring 54 is fixedly connected between the clamping pin 52 and the main body 1, and the clamping pin 52 is abutted against the clamping groove 53; namely: the soft dry caffeic acid composition particles passing through the screen 24 fall into the drawer 51, the bayonet 52 is pushed to the direction away from the drawer 51, the first spring 54 is compressed, the bayonet 52 is separated from the bayonet 53, the drawer 51 can be pulled out, the screened soft dry caffeic acid composition particles in the drawer 51 are taken out, the drawer 51 is pushed back, the bayonet 52 is pushed to enter the bayonet 53 under the action of the first spring 54, the pulling of the drawer 51 is limited, the screened soft dry caffeic acid composition particles can be collected through the drawer 51, and the next tabletting can be conveniently carried out.
Specifically, the supporting structure 6 comprises supporting columns 61, two groups of supporting columns 61 are slidably connected to the bottom end of the main body 1, a rubber pad 62 is fixedly connected to the bottom end of each supporting column 61, and a second spring 63 is abutted between each supporting column 61 and the main body 1; namely: the bottom of main part 1 is moved and is connected with two sets of support columns 61, and support column 61 bottom fixedly connected with rubber pad 62 has contradicted between support column 61 and the main part 1 and has second spring 63, and equipment will produce in the course of the work and rock, can play certain cushioning effect under the effect of rubber pad 62 and second spring 63.
Specifically, the limiting structure 7 includes a limiting block 71, one end of the shaking plate 28 is slidably connected with the limiting block 71, the shaking plate 28 is fixedly connected with a sliding rod 73, the limiting block 71 is slidably connected with the shaking plate 28 through the sliding rod 73, the shaking plate 28 is rotatably connected with a lead screw 72, the lead screw 72 is in threaded connection with the limiting block 71, one end of the limiting block 71 is abutted against the screen 24, the limiting block 71 is in an "L" shape, and one end of the lead screw 72 is fixedly connected with a knob; namely: when the screen cloth 24 needs to be replaced, go lower support rod 41 and pinch roller 42 earlier, drive lead screw 72 through rotating the knob and rotate, because lead screw 72 one end threaded connection has stopper 71, stopper 71 passes through slide bar 73 and shakes board 28 sliding connection, thereby drive stopper 71 and deviate from the screen cloth 24 motion, thereby alright promote screen cloth 24, take off screen cloth 24, change new screen cloth 24, antiport lead screw 72, drive stopper 71 to the motion of screen cloth 24 direction, because stopper 71 is "L" shape, the one end fixedly connected with knob of lead screw 72, so will make stopper 71 and screen cloth 24 conflict and not restrict the screen cloth 24 motion.
Specifically, referring to fig. 7, fig. 7 is a flow chart of a preparation process of a preparation apparatus for a sustained-release caffeic acid composition according to the present invention, wherein the preparation process of the preparation apparatus for a sustained-release caffeic acid composition is characterized in that: the method comprises the following steps:
s1: firstly, preparing the caffeic acid slow-release composition into soft materials, then preparing the soft materials into granules by a granulator, sieving the dried caffeic acid composition soft materials by using a granulating machine, after equipment is started, putting the dried caffeic acid composition soft materials into a blanking structure 3, wherein the blanking structure 3 can control blanking speed and uniformity, and the phenomenon that the dried caffeic acid composition soft materials received by a granulating structure 2 at one time are more and are not beneficial to sieving is avoided;
s2: the blanking structure 3 enables the dried soft caffeic acid composition particles to fall onto the granulating structure 2, and the granulating structure 2 is convenient for granulating and sieving the dried soft caffeic acid composition particles through shaking, so that the bonded particles are dispersed, and the later-stage tabletting is convenient;
s3: then, the whole grain structure 2 can crush and sieve the dry caffeic acid composition soft material particles adhered together through the rolling structure 4, and the screened caffeic acid composition soft material particles can be collected into the whole grain structure 5, so that the next treatment is convenient to carry out; the dispersing structure 8 can enable the granulated and dried caffeic acid composition soft material particles to uniformly fall into the collecting structure 5;
s4: when preparing the caffeic acid sustained-release tablets with different sizes and masses, the components of the sieve of the granulating structure 2 are convenient to replace through the limiting structure 7, the equipment can vibrate during working, the main body 1 can be supported through the supporting structure 6, and a certain shock absorption effect is achieved.
When the invention is used, firstly, when the caffeic acid sustained-release composition is prepared (such as caffeic acid sustained-release mixture tablets), the caffeic acid sustained-release composition is made into soft material and then made into granules by a granulator, the dried caffeic acid composition soft material granules are required to be sized and sieved, the caffeic acid composition soft material granules are placed in a lower bin 31, the caffeic acid composition soft material granules in the lower bin 31 fall onto a screen 24, a motor 21 is started, the motor 21 drives a shaking shaft 22 to rotate through a first belt 23, the shaking shaft 22 is an eccentric shaft, the shaking shaft 22 is in sliding connection with a fixed block 26 through a shaking groove 27, the fixed block 26 is fixedly connected with a shaking plate 28, the shaking plate 28 is in rotating connection with a main body 1, the motor 21 drives the shaking shaft 22 to rotate, the shaking shaft 22 drives the shaking plate 28 to shake up and down, the screen 24 is sleeved on the shaking plate 28, therefore, the screen 24 is driven to shake, so that soft caffeic acid composition particles falling onto the screen 24 are sifted, the adhered soft caffeic acid composition particles will be retained on the screen 24, the shaken screen 24 can shake the adhered soft caffeic acid composition particles, when the screen 24 cannot shake, the shaking plate 28 is inclined, so that the adhered soft caffeic acid composition particles move towards the pressing wheel 42, so as to be further crushed by the pressing wheel 42, in the shaking process of the shaking plate 28 driven by the motor 21, the top end of the shaking plate 28 is rotatably connected with the connecting rod 34, the top end of the connecting rod 34 is rotatably connected with the discharging plate 33, in the shaking process of the shaking plate 28, the discharging plate 33 is driven by the connecting rod 34 to swing to pull the blocking piece 32, so that the soft caffeic acid composition particles in the blanking bin 31 are discharged, and the soft caffeic acid composition particles will collide with the discharging plate 33, the discharging plate 33 is shaken to uniformly discharge soft caffeic acid composition particles, so that the blanking speed and uniformity can be controlled conveniently, the situation that more soft caffeic acid composition particles are received by the screen 24 at one time and are not beneficial to whole particle sieving is avoided, in the shaking process of the screen 24, the bonded soft caffeic acid composition particles move towards the pressing wheel 42, the pressing wheel 42 is rotatably connected to the main body 1 through the bottom end of the supporting rod 41, the tension spring 43 is rotatably connected between the supporting rod 41 and the main body 1, the screen 24 pushes the supporting rod 41 to swing and drives the pressing wheel 42 to roll on the screen 24, when the bonded soft caffeic acid composition particles are abutted against the pressing wheel 42, the pressing wheel 42 can crush the bonded soft caffeic acid composition particles, the bonded soft caffeic acid composition particles can pass through the screen 24 to fall off, and the purpose of crushing and sieving of the bonded soft dry caffeic acid composition particles is achieved, the nut 44 is separated from the rotating shaft 45 by rotating the nut 44, the supporting rod 41 and the rotating shaft 45 rotate, and the supporting rod 41 and the pressing wheel 42 can be removed, thereby facilitating the replacement of the screen 24, the soft particles of the dry caffeic acid composition passing through the screen 24 can fall into the drawer 51, meanwhile, under the driving of the shaking shaft 22, the driving disk 87 is driven by the second belt 82 to rotate, thereby driving the driving gear 89 fixedly connected with the driving disk 87 to rotate, thereby driving the chain 86 to move, under the action of the auxiliary rod 89a and the auxiliary gear 88, the two groups of driven gears 85 are driven to rotate, the two groups of driven gears 85 are respectively distributed at two sides of the chain 86, thereby the two groups of driven gears 85 are reversely rotated, the motor 21 rotates counterclockwise, thereby the chain 86 rotates counterclockwise, the two groups of driven gears 85 are driven to rotate back to each other, thereby driving the two groups of dispersing shafts 84 and the dispersing plate to rotate back, the soft material granule is in the middle of the play flitch 33 effect drops screen cloth 24 more to drop to in the middle of collecting box 25, can take place to pile up, be not convenient for collect box 25 and pull out, under the dispersion plate 83 effect, can make the soft material granule disperse to collect inside the box 25, thereby more even.
The bayonet 52 is pushed in the direction departing from the drawer 51, the first spring 54 is compressed, the bayonet 52 is separated from the clamping groove 53, the drawer 51 can be pulled out, the dried soft caffeic acid composition particles sieved in the drawer 51 are taken out, the drawer 51 is pushed back, the bayonet 52 is pushed to enter the clamping groove 53 under the action of the first spring 54, the pulling of the drawer 51 is limited, the sieved dried soft caffeic acid composition particles can be collected and processed through the drawer 51, the next tabletting is convenient to carry out, two groups of supporting columns 61 are movably connected to the bottom end of the main body 1, rubber pads 62 are fixedly connected to the bottom ends of the supporting columns 61, second springs 63 are abutted between the supporting columns 61 and the main body 1, the equipment can shake in the working process, certain damping effect can be achieved under the action of the rubber pads 62 and the second springs 63, when the screen 24 needs to be replaced, the supporting rods 41 and the pressing wheels 42 are firstly removed, drive lead screw 72 through rotating the knob and rotate, because lead screw 72 one end threaded connection has stopper 71, stopper 71 passes through slide bar 73 and shakes board 28 sliding connection, thereby it deviates from the motion in screen cloth 24 to drive stopper 71, thereby alright promote screen cloth 24, take off screen cloth 24, change new screen cloth 24, reverse rotation lead screw 72, drive stopper 71 and to the motion of screen cloth 24 direction, because stopper 71 is "L" shape, the one end fixedly connected with knob of lead screw 72, thereby so will make stopper 71 and screen cloth 24 conflict and not restrict the motion of screen cloth 24.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (8)
1. The equipment for preparing the caffeic acid sustained-release composition is characterized by comprising a main body (1), wherein the main body (1) is connected with a whole grain structure (2) and a blanking structure (3), the whole grain structure (2) is connected with a limiting structure (7), the main body (1) is provided with a rolling structure (4) and a collecting structure (5), the main body (1) is connected with a collecting structure (5) and a supporting structure (6), and the main body (1) is connected with a dispersing structure (8);
the dispersing structure (8) comprises dispersing shafts (84), a plurality of dispersing shafts (84) are connected to the main body (1) in a rotating mode, the dispersing shafts (84) are located on a dispersing plate (83) fixedly connected to the inside of the main body (1), a plurality of driven gears (85) are fixedly connected to one ends, penetrating through the main body (1), of the dispersing shafts (84), a driving plate (87) is connected to one end of the main body (1) in a rotating mode, a driving gear (89) is fixedly connected to one end of the driving plate (87), an auxiliary gear (88) is connected to one end, deviating from the driving plate (87), of the main body (1), chains (86) are wound and meshed on the driving gear (89), the driven gears (85) are distributed on two sides of the chains (86) in two groups, and a plurality of auxiliary rods (89a) are connected to the main body (1) in a rotating mode, it is a plurality of supplementary rod (89a) are two sets ofly distribute in one side of two sets of driven gear (85) respectively to contradict with the one end of chain (86), driving-disc (87) winding has second belt (82), main part (1) are located one side of chain (86) and can dismantle through the bolt and be connected with guard plate (81), driving-disc (87) are connected through second belt (82) and whole grain structure (2).
2. The apparatus for preparing a caffeic acid sustained-release composition according to claim 1, wherein: whole grain structure (2) are including shaking board (28), the inside of main part (1) is rotated and is connected with shaking board (28), the bottom fixedly connected with fixed block (26) of shaking board (28), be equipped with shake groove (27) on fixed block (26), main part (1) through connection has shaking shaft (22), shaking shaft (22) and shake groove (27) cup joint and with shake groove (27) sliding fit, motor (21) are installed in main part (1), motor (21) run through in main part (1) end and shake shaft (22) run through in main part (1) end through the carousel winding have first belt (23), shaking board (28) have cup jointed screen cloth (24), the one end of shaking board (28) has cup jointed and has collected box (25), shake shaft (22) is the eccentric shaft, the eccentric end and the shake groove (27) of shaking shaft (22) cup joint and sliding fit, one end of the screen (24) is provided with a groove, the groove end of the screen (24) is clamped with a shaking plate (28), and the shaking plate (28) is inclined.
3. The apparatus for preparing a caffeic acid sustained-release composition according to claim 2, wherein: feed structure (3) are including feed bin (31) down, feed bin (31) under the top fixedly connected with of main part (1), feed bin (31) bottom slip embedding has separation blade (32) down, separation blade (32) bottom is rotated and is connected with out flitch (33), it is connected with connecting rod (34) to go out flitch (33) and shake board (28) one end top rotation, shake axis (22) and connect through carousel and second belt (82) winding, the bottom of feed bin (31) is the quadrangular platform form down, the top of feed bin (31) is the quadrangular prism form down.
4. The apparatus for preparing a caffeic acid sustained-release composition according to claim 1, wherein: roll structure (4) including axis of rotation (45), the equal fixedly connected with axis of rotation (45) in one end both sides of main part (1), main part (1) rotates respectively through a pair of axis of rotation (45) and is connected with bracing piece (41), the one end threaded connection of axis of rotation (45) has nut (44), the one end and the bracing piece (41) of nut (44) are contradicted, and are a pair of the bottom of bracing piece (41) is rotated and is connected with pinch roller (42), it is connected with extension spring (43) to rotate between bracing piece (41) and main part (1).
5. The apparatus for preparing a caffeic acid sustained-release composition according to claim 1, wherein: collect structure (5) including drawer (51), main part (1) sliding connection has drawer (51), drawer (51) one end is equipped with draw-in groove (53), main part (1) is close to drawer (51) one end sliding connection has bayonet lock (52), the first spring of fixedly connected with (54) between bayonet lock (52) and main part (1), bayonet lock (52) and draw-in groove (53) are contradicted.
6. The apparatus for preparing a caffeic acid sustained-release composition according to claim 1, wherein: bearing structure (6) are including support column (61), the bottom sliding connection of main part (1) has two sets of support columns (61), support column (61) bottom fixedly connected with rubber pad (62), it has second spring (63) to contradict between support column (61) and main part (1).
7. The apparatus for preparing a caffeic acid sustained-release composition according to claim 2, wherein: limit structure (7) include stopper (71), the one end sliding connection that shakes board (28) has stopper (71), shake board (28) fixedly connected with slide bar (73), stopper (71) are through slide bar (73) and shake board (28) sliding connection, it is connected with lead screw (72) to shake board (28) rotation, lead screw (72) and stopper (71) threaded connection, stopper (71) one end and screen cloth (24) are contradicted.
8. The process for preparing an apparatus for the sustained release preparation of caffeic acid according to any one of claims 1-7, wherein: the method comprises the following steps:
s1: firstly, preparing the caffeic acid slow-release composition into soft materials, then preparing the soft materials into granules by a granulator, sieving the dried caffeic acid composition soft material granules by a whole sieve, after equipment is started, putting the dried caffeic acid composition soft material granules into a blanking structure (3), and controlling the blanking speed and uniformity by the blanking structure (3);
s2: the blanking structure (3) enables the dried soft caffeic acid composition particles to fall onto the granulating structure (2), and the granulating structure (2) can facilitate granulating and sieving of the dried soft caffeic acid composition particles through shaking, so that the bonded particles are dispersed, and tabletting can be conveniently carried out at the later stage;
s3: then the whole grain structure (2) can crush and sieve the dry caffeic acid composition soft material particles which are adhered together through the rolling structure (4), the whole grain sieved caffeic acid composition soft material particles can be collected into the inside of the collection structure (5), and the dispersing structure (8) can enable the whole grain dried caffeic acid composition soft material particles to uniformly fall into the inside of the collection structure (5);
s4: when the caffeic acid sustained-release tablets with different sizes and masses are prepared, the components of the sieving of the granulating structure (2) are convenient to replace through the limiting structure (7), the equipment can vibrate during working, and the main body (1) can be supported through the supporting structure (6).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111037755.5A CN113714094A (en) | 2021-09-06 | 2021-09-06 | Preparation equipment and preparation process of caffeic acid sustained-release composition |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111037755.5A CN113714094A (en) | 2021-09-06 | 2021-09-06 | Preparation equipment and preparation process of caffeic acid sustained-release composition |
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| CN202111037755.5A Withdrawn CN113714094A (en) | 2021-09-06 | 2021-09-06 | Preparation equipment and preparation process of caffeic acid sustained-release composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114917197A (en) * | 2022-06-16 | 2022-08-19 | 南京正科医药股份有限公司 | Levofloxacin hydrochloride tablet |
| CN115625039A (en) * | 2022-09-21 | 2023-01-20 | 连云港原舜光伏材料有限公司 | Quartz sand screening device and using method thereof |
-
2021
- 2021-09-06 CN CN202111037755.5A patent/CN113714094A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114917197A (en) * | 2022-06-16 | 2022-08-19 | 南京正科医药股份有限公司 | Levofloxacin hydrochloride tablet |
| CN115625039A (en) * | 2022-09-21 | 2023-01-20 | 连云港原舜光伏材料有限公司 | Quartz sand screening device and using method thereof |
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Application publication date: 20211130 |