CN113693784B - heart valve stent - Google Patents
heart valve stent Download PDFInfo
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- CN113693784B CN113693784B CN202110943408.2A CN202110943408A CN113693784B CN 113693784 B CN113693784 B CN 113693784B CN 202110943408 A CN202110943408 A CN 202110943408A CN 113693784 B CN113693784 B CN 113693784B
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- stent
- skirt
- shaped
- heart valve
- support
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- 210000003709 heart valve Anatomy 0.000 title claims abstract description 68
- 239000008280 blood Substances 0.000 claims abstract description 39
- 210000004369 blood Anatomy 0.000 claims abstract description 39
- 230000003205 diastolic effect Effects 0.000 claims abstract description 5
- 230000007423 decrease Effects 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 210000001765 aortic valve Anatomy 0.000 claims description 6
- 230000017531 blood circulation Effects 0.000 claims description 4
- 230000002107 myocardial effect Effects 0.000 claims description 4
- 210000004165 myocardium Anatomy 0.000 claims description 4
- 238000005452 bending Methods 0.000 claims description 3
- 239000012528 membrane Substances 0.000 claims 2
- 210000002489 tectorial membrane Anatomy 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 8
- 210000002837 heart atrium Anatomy 0.000 description 8
- 230000008859 change Effects 0.000 description 6
- 238000001125 extrusion Methods 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- 239000007787 solid Substances 0.000 description 3
- 206010067171 Regurgitation Diseases 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000010030 laminating Methods 0.000 description 2
- 210000005240 left ventricle Anatomy 0.000 description 2
- 210000004115 mitral valve Anatomy 0.000 description 2
- 210000005241 right ventricle Anatomy 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000003959 Ventricular Outflow Obstruction Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 210000003157 atrial septum Anatomy 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000010247 heart contraction Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000013152 interventional procedure Methods 0.000 description 1
- 210000005246 left atrium Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000001147 pulmonary artery Anatomy 0.000 description 1
- 210000003102 pulmonary valve Anatomy 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000000591 tricuspid valve Anatomy 0.000 description 1
- 210000000596 ventricular septum Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
Abstract
The embodiment of the invention discloses a heart valve support, which comprises: an outer stent and an inner stent, wherein the outer stent at least comprises a first stent and a second stent which are connected along the radial direction, and a free port of the first stent is a diastolic blood outflow port; the section of the second bracket is a D-shaped or oval closed loop surrounded by at least two convex curves; the inner support is of a tubular structure arranged in the outer support, and blood unidirectional flow is controlled through a tectorial membrane arranged on the wall of the inner support and valve blades arranged in the inner support; a horn-shaped skirt connected to the blood inflow end of the second stent or to the blood inflow end of the inner stent; and connecting structures are arranged in the outer bracket and between the skirt edge and the outer bracket, and the connecting structures are connected end to end by a plurality of S-shaped structures.
Description
The application date of the parent application of the divisional application is 2018, 9 and 21, the application number is 201811107088.1, and the invention is named as a heart valve stent.
Technical Field
The embodiment of the invention relates to medical equipment, in particular to a heart valve bracket.
Background
The heart is divided into left and right parts, each part comprising a ventricle and an atrium, the ventricles being separated from each other and from each other by a ventricular septum and a atrial septum, and valves being provided between the ventricles, the ventricles and the arteries to prevent reflux of blood. The valve between the left atrium and the left ventricle is a mitral valve, the valve between the right atrium and the right ventricle is a tricuspid valve, the valve between the left ventricle and the aorta is an aortic valve, and the valve between the right ventricle and the pulmonary artery is a pulmonary valve.
The valve opens and closes in response to the heart's contraction and relaxation, and therefore the heart valve must withstand long-term blood washout and compression of the blood and surrounding annulus. When the valve is not fully closed and not fully opened, insufficient blood supply and regurgitation will result, and in order to improve the blood supply and regurgitation, physicians sometimes recommend placement of a heart valve stent by minimally invasive interventional procedures. However, the existing heart valve stent has poor compliance, cannot be well attached to an atrium, is easy to cause the occurrence of paravalvular leakage, influences the fixing effect of the heart valve stent, and reduces the service life of the heart valve stent.
Disclosure of Invention
The embodiment of the invention provides a heart valve support, which solves the technical problems that the existing heart valve support is poor in compliance and difficult to attach to the heart well.
The invention adopts the following technical scheme:
a heart valve stent comprising:
an outer stent comprising at least a first stent and a second stent connected in a radial direction, the free port of the first stent being a diastolic blood outflow port; the section of the second bracket is a D-shaped or oval closed loop surrounded by at least two convex curves;
the inner support is of a tubular structure arranged in the outer support, and blood unidirectional flow is controlled through a covering film arranged on the wall of the inner support and valve blades arranged in the inner support;
a horn-shaped skirt connected to the blood inflow end of the second stent or to the blood inflow end of the inner stent;
the outer bracket comprises a plurality of diamond-shaped supporting units which are connected with each other, and the skirt comprises a plurality of V-shaped structures; a connecting structure is arranged between the free ends of the two sides of the V-shaped structure of the skirt and the free top angles of the diamond-shaped supporting units of the second bracket, or a connecting structure is arranged between the free ends of the two sides of the V-shaped structure of the skirt and the blood inflow end of the inner bracket; the connection structure can enhance the deformation compliance of the connection. Further, the connection structure comprises an S-shaped structure.
Further, the connecting structure is formed by connecting a plurality of S-shaped structures end to end.
Further, the outer bracket comprises a plurality of diamond-shaped supporting units which are connected with each other, each diamond-shaped supporting unit is connected with each other through a vertex angle, the skirt comprises a plurality of V-shaped structures, and free ends of two sides of each V-shaped structure are connected with the free vertex angles of the diamond-shaped supporting units on the top of the second bracket or connected with the blood inflow end of the inner bracket.
Further, the free ends of the two sides of the V-shaped structure are connected with the vertex angles of the diamond-shaped supporting units and the vertex angles of the adjacent diamond-shaped supporting units through the connecting structure.
Further, the projection of the connecting structure along the length direction is vertically or obliquely arranged. Further, the diameter of the second bracket gradually decreases from the middle part of the second bracket to the connection part of the second bracket and the skirt. 6. The heart valve stent of claim 1, wherein the cross section of the second stent is a D-shaped or oval closed loop surrounded by two convex curves or a D-shaped closed loop surrounded by three convex curves; the ratio between the maximum diameter and the minimum diameter of the closed loop ranges from 1 to 1.5.
Further, the included angle between the skirt and the second stent body is a gradual change included angle, and the included angle between the aortic valve and the second stent is smaller than the included angle between the myocardial and the second stent; the included angle between the skirt edge and the second bracket main body is 50-90 degrees.
Further, the outer bracket has a greatest stiffness at the junction of the second bracket and the first bracket.
Further, the radius of the first stent gradually decreases along the direction of blood flow in diastole.
Further, a plurality of rows of barbs are arranged on the outer side of the first bracket, and the barbs are arc-shaped and bend towards the second bracket.
Further, a sealing film is arranged on the inner side surface of the skirt edge, and a gap is reserved between the free edge of the sealing film and the second bracket at the joint of the skirt edge and the second bracket.
Further, a gap is reserved between the outer support and the inner support, so that the outer support is prevented from affecting the normal opening and closing of the valve leaflet of the inner support when deformed along with the myocardial.
Further, when the section of the second bracket is a D-shaped closed loop formed by a first convex curve and a second convex curve, the curvature of the first convex curve is larger than that of the second convex curve, and the first convex curve is a symmetrical curve; the skirt edge is provided with two or three developing points, and specifically comprises:
when the number of the developing points is 2, one developing point is arranged on a central intersecting line, the central intersecting line is formed by vertically cutting the skirt edge corresponding to the first convex curve by a plane where the connecting lines of the central points of the plurality of first convex curves are located, the other developing point is arranged on one of two end intersecting lines, the two end intersecting lines are formed by cutting the skirt edge by the plane where the end points of the first convex curve or the end points of the second convex curve of the plurality of sections are located, and the sizes and/or the shapes of the two developing points are different.
When the number of the developing points is 3, one developing point is arranged on a central intersecting line, the central intersecting line is formed by vertically cutting the skirt edge corresponding to the first convex curve by a plane where the connecting lines of the central points of the plurality of first convex curves are located, the other two developing points are respectively arranged on two end intersecting lines, the two end intersecting lines are formed by cutting the skirt edge by the plane where the end points of the first convex curve or the end points of the second convex curve of the plurality of sections are located, and at least two developing points in the three developing points are different in size and/or shape.
Further, the free end of the skirt is bent inwards to the inner side of the skirt, and the range of a round angle formed by bending the skirt is between 90 degrees and 180 degrees.
The technical scheme of the heart valve stent provided by the embodiment of the invention comprises an outer stent, an inner stent and a skirt, wherein the outer stent at least comprises a first stent and a second stent which are connected in the radial direction, and a free port of the first stent is a blood outflow port; the section of the second bracket is a D-shaped or oval closed loop surrounded by at least two convex curves; the inner support is arranged in the tubular structure in the outer support, and the unidirectional flow of blood is controlled through a tectorial membrane arranged on the wall of the inner support and valve blades arranged in the inner support; a horn-shaped skirt connected to the blood inflow end of the second stent or to the blood inflow end of the inner stent; and a connecting structure is arranged in the outer bracket and/or between the skirt edge and the outer bracket, and the connecting structure is formed by connecting a plurality of S-shaped structures end to end. The closed loop formed by encircling the plurality of convex curves can not only effectively prevent blood from flowing back and realize good fixation, but also effectively avoid blocking of the outflow channel, thereby greatly prolonging the service life of the heart valve support and improving the life quality of users. Further, through set up connection structure in the outer support or between shirt rim and the outer support, can make the relative position of shirt rim and support main part change more easily, and then make the chassis of shirt rim softer, it is better to warp the compliance, can with the laminating of atrium better.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic elevation view of a heart valve stent provided in an embodiment of the present invention;
FIG. 2 is a schematic top view of a heart valve stent provided in an embodiment of the present invention;
FIG. 3 is a schematic structural view of a second bracket section according to an embodiment of the present invention;
FIG. 4 is a schematic structural view of a cross section of a second bracket according to an embodiment of the present invention;
FIG. 5 is a schematic structural view of a cross section of a second bracket according to an embodiment of the present invention;
FIG. 6 is a schematic diagram of a second bracket section provided by an embodiment of the present invention before and after stressing;
FIG. 7 is a schematic illustration of a skirted heart valve stent in accordance with an embodiment of the present invention;
FIG. 8 is a schematic view of a heart valve stent with a gradual change in included angle between the skirt and the second stent body according to an embodiment of the present invention;
FIG. 9 is an enlarged schematic view of the connection structure between diamond-shaped support units and between diamond-shaped and V-shaped structures provided by an embodiment of the present invention;
FIG. 10A is an enlarged view of a portion of L of FIG. 9 in a preferred embodiment;
FIG. 10B is an enlarged view of a portion of L of FIG. 9 in another preferred embodiment;
FIG. 11A is a schematic view of a visualization structure and its placement position of a heart valve stent according to an embodiment of the present invention;
FIG. 11B is a further schematic illustration of a visualization structure and its placement position of a heart valve stent provided in accordance with an embodiment of the present invention;
fig. 11C is a further schematic view of a developing structure of a heart valve stent and a placement position thereof according to an embodiment of the present invention.
Description of the reference numerals:
11-an outer stent; 111-a first scaffold; 1111-barbs; 112-a second scaffold; 12-inner stent, 1211-connecting structure; 13-coating; 14-valve; 15-skirt edge; 151-aortic valve skirt; 152-myocardial skirt.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described by means of implementation examples with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Examples
An embodiment of the present invention provides a heart valve stent for replacing a diseased mitral valve to participate in blood flow control of the heart, as shown in fig. 1 and 2, the heart valve stent comprising: an outer stent 11 and an inner stent 12, the outer stent 11 comprising at least a first stent 111 and a second stent 112 connected in the radial direction, the free port of the first stent 111 being the diastolic blood outflow port of the atrium; the cross section of the second bracket 112 is a D-shaped or oval closed loop surrounded by at least two convex curves, and the ratio between the maximum diameter and the minimum diameter of the closed loop ranges from 1 to 1.5; the inner stent 12 is provided in a tubular structure inside the outer stent 11, and controls unidirectional flow of blood through a coating 13 provided on a wall of the inner stent 12 and a leaflet 14 provided inside the inner stent 12.
The outer bracket 11 and the inner bracket 12 of the present embodiment are preferably connected together by riveting, but of course, they may be connected together by sewing or the like.
In order to effectively prevent blood reflux and achieve good fixation, the cross section of the second bracket 112 of the present embodiment is preferably a D-shaped or oval closed loop surrounded by two convex curves, as shown in fig. 3 and 4; or a D-shaped closed loop surrounded by three convex curves, as shown in fig. 5. Taking the section of the second support 112 as a D-shaped closed-loop structure for example, the D-shaped closed-loop structure includes a first curve corresponding to a large arc and a second curve corresponding to a small arc, if the second curve is a straight line, the straight line becomes a concave curve due to extrusion of an annulus during the use of the heart valve, and the deformation can cause a gap between the heart valve support and the annulus, so that the condition of blood reflux occurs. In this embodiment, the second curve is a convex curve, which can bear a larger extrusion force, and perhaps the curvature of the second curve is reduced under the action of the extrusion force, but the second curve is not changed into a concave curve, so that the condition of blood reflux is not generated, and the safety of the heart valve is improved.
It should be noted that, for convenience of description, in this embodiment, a first curve corresponding to a large arc is named as a first convex curve, a second curve corresponding to a small arc is named as a second convex curve, and when the D-shaped closed loop is surrounded by three convex curves, a shape surrounded by two convex curves is like the first convex curve, and an intersection point of the two convex curves is a center point of the first convex curve.
For the range of the ratio between the maximum diameter and the minimum diameter, the embodiment is illustrated by taking a D-shaped closed loop structure surrounded by two curves as an example, as shown in fig. 6, the distance between the two symmetrical points farthest from the first convex curve is the maximum diameter D1, the distance between the center point of the first convex curve and the center point of the second convex curve is the minimum diameter D2, and the range of the ratio between the maximum diameter D1 and the minimum diameter D2 in the embodiment is 1-1.5.
To further enhance the fixation effect of the heart valve stent, as shown in fig. 7, the heart valve stent of the present embodiment further comprises a horn-shaped skirt 15, wherein the skirt 15 is connected to the blood inflow end of the second stent 112 or to the blood inflow end of the inner stent 12, and the included angle between the skirt 15 and the main body of the second stent 112 is in the range of 50-90 degrees. The skirt 15 of the present embodiment may have a symmetrical structure or an asymmetrical structure. Specifically, as shown in fig. 7, the included angle between the skirt 15 and the main body of the second bracket 112 may be the same everywhere; as shown in fig. 8, the included angle between the skirt 15 and the second bracket 112 may also be gradually changed, specifically: the first angle between the skirt 15 and the body of the second stent 112 near the aortic valve and the second stent 112 is smaller than the second angle between the skirt 15 and the second stent 112 at the myocardium, wherein the aortic valve skirt 151 at the aortic valve is in a position opposite to the myocardial skirt 152 at the myocardium, see in particular fig. 8. Through the gradual change contained angle design between shirt rim 15 and the second support 112 main part, improve the fixed effect of heart valve support, and then improve heart valve support's life.
In order to prevent the free end of the skirt from contacting with the inner wall of the atrium to damage the inner wall of the atrium, the free end of the skirt in this embodiment is bent inwards to the inner side of the skirt, and the range of the rounded angle formed by bending the skirt is between 90 degrees and 180 degrees.
In order to further improve the fixing effect of the heart valve stent, the diameter of the second stent 112 of the heart valve stent of the present embodiment gradually decreases from the middle of the second stent 112 to the connection between the second stent 112 and the skirt 15, so that the heart valve stent is thin in the middle and thick at both ends, and the fixing effect of the heart valve stent can be improved well. Further, the rigidity of the outer support at the superposition part of the first support and the second support, namely the connection part of the first support and the second support is the greatest, so that the skirt edge is better fitted with the atrium.
In order to improve the convenience of release and fixation of the heart valve stent, the outer stent of the heart valve stent of the present embodiment comprises a plurality of diamond-shaped supporting units connected to each other, as shown in fig. 9, and each diamond-shaped supporting unit is connected to each other by a vertex angle, and the skirt 15 comprises a plurality of V-shaped structures, the free ends of both sides of which are connected to the free vertex angle of the diamond-shaped supporting unit on the top of the second stent 112 or to the blood inflow end of the inner stent. Through the variability of the V-shaped structure and the diamond-shaped structure, the variability of the shape of the outer stent and the shape of the skirt edge is improved, and the convenience of release and fixation of the heart valve stent is further improved. Further, as shown in fig. 9, the free ends of the two sides of the V-shaped structure are connected with the top corners of the diamond-shaped supporting units and the top corners of the adjacent diamond-shaped supporting units through connection structures 1211, as shown in the enlarged schematic view of the L-shaped part in fig. 10A, and the connection structures 1211 are formed by connecting a plurality of S-shaped structures end to end.
Specifically, the connecting structure 1211 is formed of an S-shaped structure formed of a series of alternating curved and straight sections and connecting sections at both ends, and referring to fig. 10A and 10B, adjacent straight sections are nearly parallel to each other and adjacent curved sections are closely adjacent to each other, which can provide greater deformation compliance and better stability.
The projection of the connecting structure 1211 along the length direction is vertically arranged (as shown in fig. 10A) or obliquely arranged (as shown in fig. 10B), or the length direction of the connecting sections at two ends of the connecting structure 1211 is deflected at a certain angle with the length direction of the S-shaped structure (as shown in fig. 10B).
In the embodiment provided in fig. 10B, due to the inclined projection of the connecting structure 1211 along the length direction, the connecting structure 1211 can make the V-shaped structure of the skirt and the relative position of the stent body easier to change, so that the skirt chassis is softer and more compliant, and the fixing effect of the heart valve stent can be further improved by describing the shape of the second stent 112 (i.e. the diameter of the second stent 112 is gradually reduced from the middle of the second stent 112 to the connection between the second stent 112 and the skirt 15) as in the above embodiment. As can be seen from fig. 9, since the outer stent is formed by connecting a plurality of diamond-shaped supporting units, if the number of diamond-shaped supporting units in the transverse direction of the outer stent increases in the case of a certain outer stent diameter, the diamond-shaped structure becomes longer in the radial direction due to extrusion, so that the radial length of the outer stent increases with the increase of the number of the transverse diamond-shaped supporting units and decreases with the decrease of the number of the transverse diamond-shaped supporting units.
In order to prevent the heart valve stent from piercing the heart wall at the blood output end of the diastole, i.e. at the opposite end of the connecting end of the first stent and the second stent, the radius of the first stent is gradually reduced along the blood flow direction of the diastole, as shown in fig. 7, and the design can also prevent left ventricular outflow obstruction.
In order to improve the fixing effect of the heart valve stent, as shown in fig. 7, 8 and 9, the heart valve stent of the present embodiment is provided with a plurality of rows of barbs 1111 on the outer side of the first stent, and the barbs 1111 are arc-shaped and bent toward the second stent 112. Preferably, the closest distance of the barbs 1111 from the skirt 15 stent is in the range of 6-14mm, and the arcuate design of the barbs 1111 prevents them from puncturing the sheath and also improves the anchoring effect of the heart valve stent.
Further, the inner side surface of the skirt 15 is provided with a sealing film, and a gap is left between the free edge of the sealing film and the second bracket 112 at the joint of the skirt 15 and the second bracket 112, and the gap can facilitate the inflow of blood to form thrombus, thereby playing a better sealing role. In addition, a gap is reserved between the outer support 11 and the inner support 12, so that the normal opening and closing of the valve blades of the inner support 12 can be prevented from being influenced when the outer support 11 deforms along with the cardiac muscle.
When a heart valve stent is implanted in a human body, a doctor is required to determine whether an implantation position is accurate through a developing point provided at an implanted heart valve, and since the heart valve is a three-dimensional structure, it is required to determine whether a spatial position thereof is accurate, and thus it is required to judge whether the spatial position thereof is accurate through positions of a plurality of developing points. In order to facilitate the determination of the spatial position of the implanted heart valve stent, the skirt of the heart valve stent of the present embodiment is provided with two or three developing points, and the second stent cross section is illustrated as a D-shaped structure, when the second stent cross section is a D-shaped closed loop formed by a first convex curve and a second convex curve, the curvature of the first convex curve is greater than the curvature of the second convex curve, and the first convex curve is a symmetrical curve; the skirt is provided with two or three developing points.
It will be appreciated that there may be at least one intersection of a plane with a solid structure, and that there may be one intersection when a plane intersects only one face of a solid structure, and two intersections when a plane intersects two faces of a solid structure. FIGS. 11A and 11B show the case of two developing points, wherein one developing point is arranged on a central intersecting line formed by vertically cutting the skirt corresponding to the first convex curve on a plane where the central point connecting lines of the plurality of first convex curves are located; the other developing point is arranged on one of two end intersecting lines, the two end intersecting lines are formed by plane cutting skirt edges where end points of first convex curves or end points of second convex curves of a plurality of sections are located, the two developing points are different in size and/or shape, and it is to be noted that when the D-shaped closed loop structure is formed by three convex curves, the two convex curves enclose a shape like the first convex curve, at the moment, the two convex curves can be regarded as one convex curve, and the intersection point position of the two convex curves is the center point of the first convex curve. Fig. 11C shows a case of three developing points, when the number of developing points is 3, one developing point is disposed on a central intersecting line, the central intersecting line is formed by vertically cutting a skirt corresponding to the first convex curve on a plane where a central point connecting line of the plurality of first convex curves is located, and the other two developing points are respectively disposed on two end intersecting lines, the two end intersecting lines are formed by cutting a skirt on a plane where an end point of the first convex curve or an end point of the second convex curve of the plurality of cross sections is located, and at least two developing points are different in size and/or shape. It will be appreciated that the first convex curves of the plurality of sections have at least four end points, and that the plane in which the end points lie has two intersecting lines with the skirt.
The technical scheme of the heart valve stent provided by the embodiment of the invention comprises an outer stent and an inner stent, wherein the outer stent at least comprises a first stent and a second stent which are connected in the radial direction, and a free port of the first stent is a blood outflow port; the section of the second bracket is a D-shaped or oval closed loop surrounded by at least two convex curves; the inner support is arranged in the tubular structure in the outer support, and the unidirectional flow of blood is controlled through a tectorial membrane arranged on the wall of the inner support and valve blades arranged in the inner support; a horn-shaped skirt connected to the blood inflow end of the second stent or to the blood inflow end of the inner stent; and connecting structures are arranged in the outer bracket and between the skirt edge and the outer bracket, and the connecting structures are connected end to end by a plurality of S-shaped structures. The closed loop formed by the plurality of convex curves can not only effectively prevent blood from flowing back and realize good fixation, but also effectively avoid blocking of an outflow channel, thereby greatly prolonging the service life of the heart valve bracket and improving the life quality of a user; through setting up connection structure, not only further improved the variability of outer support shape for heart valve support release and fixed convenience are higher, can also make the relative position of shirt rim and support main part change more easily, and then make the chassis of shirt rim softer, and deformation compliance is better, can with the laminating of atrium better.
Note that the above is only a preferred embodiment of the present invention and the technical principle applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, while the invention has been described in connection with the above embodiments, the invention is not limited to the embodiments, but may be embodied in many other equivalent forms without departing from the spirit or scope of the invention, which is set forth in the following claims.
Claims (16)
1. A heart valve stent, comprising:
the external support at least comprises a first support and a second support which are connected in the axial direction, and the free port of the first support is a diastolic blood outflow port; the section of the second bracket is a D-shaped or oval closed loop formed by at least two convex curves, and the ratio of the maximum diameter to the minimum diameter of the closed loop is 1-1.5;
the inner support is of a tubular structure arranged in the outer support, and blood unidirectional flow is controlled through a covering film arranged on the wall of the inner support and valve blades arranged in the inner support;
a horn-shaped skirt connected to the blood inflow end of the second stent or to the blood inflow end of the inner stent;
the outer bracket comprises a plurality of diamond-shaped supporting units which are connected with each other, and the skirt comprises a plurality of V-shaped structures; a connecting structure is arranged between the free ends of the two sides of the V-shaped structure of the skirt and the free top angles of the diamond-shaped supporting units of the second bracket, or a connecting structure is arranged between the free ends of the two sides of the V-shaped structure of the skirt and the blood inflow end of the inner bracket; the connecting structure consists of a structure formed by a series of alternating bent sections and straight sections and connecting sections at two ends, wherein adjacent straight sections are nearly parallel, and adjacent bent sections are closely adjacent; the connection structure can enhance the deformation compliance of the connection.
2. The heart valve stent of claim 1, wherein the connecting structure comprises an S-shaped structure.
3. The heart valve stent of claim 1 or 2, wherein the connecting structure is formed by a plurality of S-shaped structures connected end to end.
4. A heart valve stent as in claim 3, wherein the outer stent comprises a plurality of interconnected diamond-shaped support elements, each of the diamond-shaped support elements being connected by a vertex angle, the skirt comprises a plurality of V-shaped structures, the free ends of the two sides of the V-shaped structures being connected to the free vertices of the diamond-shaped support elements on top of the second stent or to the blood inflow end of the inner stent.
5. The heart valve stent of claim 4, wherein free ends of both sides of the V-shaped structure are connected to the apex angle of the diamond-shaped support unit and the apex angle of the adjacent diamond-shaped support unit by the connection structure.
6. The heart valve stent of claim 5, wherein the projection of the connecting structure along the length is disposed vertically or obliquely.
7. The heart valve stent of claim 1, wherein the diameter of the second stent decreases from a middle portion of the second stent to a junction of the second stent and the skirt.
8. The heart valve stent of claim 1, wherein the cross-section of the second stent is a D-shaped or oval-shaped closed loop surrounded by two convex curves or a D-shaped closed loop surrounded by three convex curves.
9. The heart valve stent of claim 1, wherein the angle between the skirt and the second stent body is a gradual angle and the angle between the aortic valve and the second stent is less than the angle between the myocardial valve and the second stent; the included angle between the skirt edge and the second bracket main body is 50-90 degrees.
10. The heart valve stent of claim 1 or 9, wherein the outer stent is greatest in stiffness at the junction of the second stent and the first stent.
11. The heart valve stent of claim 1, wherein the radius of the first stent decreases gradually in the direction of diastolic blood flow.
12. The heart valve stent of any one of claims 1, 8 or 9, wherein the outer side of the first stent is provided with a plurality of rows of barbs, the barbs being arcuate and curving toward the second stent.
13. The heart valve stent of claim 1 or 9, wherein the inner side of the skirt is provided with a sealing membrane and the free edge of the sealing membrane is spaced from the second stent at the juncture of the skirt and the second stent.
14. The heart valve stent of claim 1, wherein a gap is left between the outer stent and the inner stent to prevent the outer stent from affecting the normal opening and closing of the leaflets of the inner stent as the outer stent deforms with the heart muscle.
15. The heart valve stent of claim 1 or 9, wherein when the cross-section of the second stent is a D-shaped closed loop formed by a first convex curve and a second convex curve, the curvature of the first convex curve is greater than the curvature of the second convex curve, and the first convex curve is a symmetric curve; the skirt edge is provided with two or three developing points, and specifically comprises:
when the number of the developing points is 2, one developing point is arranged on a central intersecting line, the central intersecting line is formed by vertically cutting a skirt edge corresponding to a plurality of first convex curves by a plane where the connecting lines of the central points of the first convex curves are positioned, the other developing point is arranged on one of two end intersecting lines, the two end intersecting lines are formed by cutting the skirt edge by the plane where the end points of the first convex curves or the end points of the second convex curves of the plurality of sections are positioned, and the sizes and/or the shapes of the two developing points are different;
when the number of the developing points is 3, one developing point is arranged on a central intersecting line, the central intersecting line is formed by vertically cutting the skirt edge corresponding to the first convex curve by a plane where the connecting lines of the central points of the plurality of first convex curves are located, the other two developing points are respectively arranged on two end intersecting lines, the two end intersecting lines are formed by cutting the skirt edge by the plane where the end points of the first convex curve or the end points of the second convex curve of the plurality of sections are located, and at least two developing points in the three developing points are different in size and/or shape.
16. The heart valve stent of claim 1 or 9, wherein the skirt free ends curve inwardly toward the inside of the skirt and the fillet formed by the bending of the skirt ranges between 90 degrees and 180 degrees.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110943408.2A CN113693784B (en) | 2018-09-21 | 2018-09-21 | heart valve stent |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110943408.2A CN113693784B (en) | 2018-09-21 | 2018-09-21 | heart valve stent |
| CN201811107088.1A CN109106470B (en) | 2018-09-21 | 2018-09-21 | Heart valve support |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201811107088.1A Division CN109106470B (en) | 2018-09-21 | 2018-09-21 | Heart valve support |
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| CN113693784A CN113693784A (en) | 2021-11-26 |
| CN113693784B true CN113693784B (en) | 2024-01-16 |
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| CN202110943408.2A Active CN113693784B (en) | 2018-09-21 | 2018-09-21 | heart valve stent |
| CN201811107088.1A Active CN109106470B (en) | 2018-09-21 | 2018-09-21 | Heart valve support |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201811107088.1A Active CN109106470B (en) | 2018-09-21 | 2018-09-21 | Heart valve support |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110575286A (en) * | 2019-10-11 | 2019-12-17 | 上海纽脉医疗科技有限公司 | Heart valve outer support and artificial heart valve |
| CN113558822A (en) * | 2021-07-23 | 2021-10-29 | 上海欣吉特生物科技有限公司 | Interventional mitral valve replacement system |
| CN113855324A (en) * | 2021-09-18 | 2021-12-31 | 上海欣吉特生物科技有限公司 | Valve support reaches intervention mitral valve replacement system including it |
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| CN105520792A (en) * | 2016-02-02 | 2016-04-27 | 上海纽脉医疗科技有限公司 | D-shaped invasive prosthetic heart valve |
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| CN2559333Y (en) * | 2002-03-29 | 2003-07-09 | 中南大学湘雅二医院 | Elastic valvular ring pericardium mitral valve |
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| JP5390597B2 (en) * | 2008-05-09 | 2014-01-15 | エドワーズ ライフサイエンシーズ コーポレイション | Annuloplasty ring specific to degenerative valvular disease |
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- 2018-09-21 CN CN201811107088.1A patent/CN109106470B/en active Active
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| CN107028685A (en) * | 2011-10-19 | 2017-08-11 | 托尔福公司 | Artificial heart valve film device, artificial mitral valve and related systems and methods |
| CN105520792A (en) * | 2016-02-02 | 2016-04-27 | 上海纽脉医疗科技有限公司 | D-shaped invasive prosthetic heart valve |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113693784A (en) | 2021-11-26 |
| CN109106470B (en) | 2021-08-06 |
| CN109106470A (en) | 2019-01-01 |
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