CN113693774B - Protection device for monkey autonomous administration embedded pipeline - Google Patents
Protection device for monkey autonomous administration embedded pipeline Download PDFInfo
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- CN113693774B CN113693774B CN202110897267.5A CN202110897267A CN113693774B CN 113693774 B CN113693774 B CN 113693774B CN 202110897267 A CN202110897267 A CN 202110897267A CN 113693774 B CN113693774 B CN 113693774B
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- 241000282693 Cercopithecidae Species 0.000 title claims abstract description 60
- 239000007788 liquid Substances 0.000 claims abstract description 105
- 230000001681 protective effect Effects 0.000 claims abstract description 32
- 239000003814 drug Substances 0.000 claims abstract description 30
- 238000007789 sealing Methods 0.000 claims description 18
- 238000012546 transfer Methods 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 14
- 238000003860 storage Methods 0.000 claims description 12
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 210000001503 joint Anatomy 0.000 claims 1
- 238000002474 experimental method Methods 0.000 abstract description 9
- 238000001647 drug administration Methods 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 17
- 230000000694 effects Effects 0.000 description 12
- 206010012335 Dependence Diseases 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002431 foraging effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
- A61M5/1428—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation with manual pumping action
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2250/00—Specially adapted for animals
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The application relates to equipment for medical experiments, in particular to a protection device for a monkey autonomous drug administration embedded pipeline, wherein a wearing device is worn on a monkey body, and the protection device for the embedded pipeline comprises a protection box fixed on the wearing device, a liquid-through pipe connected to the protection box and a protection pipe arranged outside the liquid-through pipe; one end of the protective tube is fixedly connected to the protective box, and the other end of the protective tube is rotatably connected to a side plate of the cage where the monkey is located. The utility model has the advantages of promote the stability of logical liquid piping connection, the smoothness nature of letting in the liquid medicine, reduce the problem that the weeping or be the pipeline jam appear.
Description
Technical Field
The application relates to equipment for medical experiments, in particular to a protection device for a monkey autonomous drug administration embedded pipeline.
Background
The autonomous administration is an operation type behavior experiment, which changes the behavior of animals before and after contacting the medicines by utilizing the strengthening effect of the medicines, is the most direct method for researching the mechanism of the addiction of the medicines and evaluating the anti-addiction efficacy of the medicines, simulates the whole process of addiction to the greatest extent from the administration, maintenance and withdrawal to foraging, and is the model with the most testing effectiveness. The non-human primate (such as monkey) is the closest to human in relation, is similar to human in physiological, anatomical and behavioral aspects, is more suitable for long-time drug addiction research, can better simulate the pathological processes of human addiction and relapse, and has irreplaceable importance in addiction research.
In the experimental process of the non-human primate, an embedded pipe is required to be implanted in the monkey body, the embedded pipe is connected with a venous system of the animal, a liquid through pipe is additionally arranged and connected with the embedded pipe, and the liquid through pipe is communicated with a liquid medicine storage container, so that the liquid medicine is conveyed into the monkey body through the liquid through pipe and the embedded pipe; the monkey body is worn with armor, wherein a protective box is fixedly connected at the position of the armor, which is positioned at the back of the monkey, a universal valve is arranged on the protective box, and a liquid through pipe is connected with an embedded pipe through the universal valve; the other end of the liquid through pipe penetrates to the outer side of the cage where the monkey is located and is used for being connected with a liquid medicine storage container.
In the process of carrying out the experiment, the monkey is movable in the cage, through the universal valve that sets up, can reduce the liquid pipe distortion and buckle and lead to the problem that the liquid pipeline is blockked up, play the effect of releasing the torsion force of liquid pipe.
With respect to the related art in the above, the inventors found that: in the process of carrying out the experiment, monkey moves in the cage, drives the universal valve and rotates in order to release the torsion that produces, under the too big or long-time circumstances of using of torsion that animal activity produced, causes the damage to the valve of universal valve easily, leads to the problem of weeping easily under the valve damage condition, can cause the appearance error of the appearance of the internal injection liquid medicine of animal to the one hand, can cause universal valve hookup location department to appear in addition, causes the hindrance to its rotation, leads to the problem that the in-process that animal activity led to the fact the distortion of liquid pipe to block.
Disclosure of Invention
In order to improve the stability of liquid pipeline connection and the smoothness of leading in the liquid medicine, this application provides a monkey independently administrates protection device of pre-buried pipeline.
The application provides a protection device of embedded pipeline of monkey autonomous administration adopts following technical scheme:
the monkey is independently administrated a protection device of an embedded pipeline, wearing equipment on the monkey body, wherein the protection device of the embedded pipeline comprises a protection box fixed on the wearing equipment, a liquid-passing pipe connected to the protection box and a protection pipe arranged outside the liquid-passing pipe; one end of the protective tube is fixedly connected to the protective box, and the other end of the protective tube is rotatably connected to a side plate of the cage where the monkey is located
Through adopting above-mentioned technical scheme, protection pipe one end rigid coupling is on the protection box, and the other end rotates with the cage curb plate to be connected, carries out the in-process of experiment, and the monkey moves in the cage, drives logical liquid pipe and protection pipe and twists reverse, and protection pipe rotates with the cage curb plate to be connected, can comparatively convenient to the twist reverse that monkey activity produced and eliminate, reduces the problem that causes inside logical liquid pipe to block up, and in longer use, is difficult to appear pipeline damage, weeping scheduling problem, keeps smooth and easy and the stability that the liquid medicine was carried.
Optionally, the protection pipe has the spliced pole towards the one end rigid coupling of protection box, threaded connection has the lantern ring of connection on the spliced pole, lantern ring threaded connection is on the protection box.
Through adopting above-mentioned technical scheme, when being connected protection pipe and cage curb plate, directly screw up the lantern ring of will connecting at the protection pipe tip, later screw up the lantern ring of will connecting on the protection box, can accomplish the rigid coupling of protection pipe and protection box, the operation is comparatively convenient.
Optionally, the end part of the liquid passing pipe penetrating into the protection box is connected with a switching pipe for connecting with an embedded pipe in the monkey body, and the liquid passing pipe and the embedded pipe are respectively sleeved at two ends of the switching pipe; a limiting component used for limiting the position of the adapter tube is arranged in the protection box.
Through adopting above-mentioned technical scheme, when being connected through liquid pipe and the internal pre-buried pipe of monkey, directly establish through liquid pipe and pre-buried pipe at the both ends of switching pipe respectively, can realize being connected through liquid pipe and pre-buried pipe, the operation is comparatively convenient, in the in-process of using, is difficult to appear leaking the problem of liquid, sets up limiting component and prescribes a limit to the position of switching pipe, can reduce the pre-buried pipe and rock, the problem of skew, keeps the stability of pre-buried pipe.
Optionally, the limiting component comprises two clamping columns hinged on the protection box, the end parts of the clamping columns in the protection box are fixedly connected with clamping rings, and the two clamping rings are clamped on the transfer tube; an adjusting handle is fixedly connected to one end of the clamping column, which faces the outside of the protection box, a communication hole is formed in the protection box, one end of the clamping column, which is connected with the adjusting handle, is positioned in the communication hole, and when the clamping ring is clamped on the transfer tube, the adjusting handle is positioned in the communication hole; the protection box is provided with a positioning component for fixing the adjusting handle.
Through adopting above-mentioned technical scheme, when using spacing subassembly to define the position of adapter, drive two grip posts through the adjustment handle and rotate, two grip rings press from both sides tightly on the adapter, later fix the position of adjustment handle through locating component, can accomplish the stability to adapter position, the operation is comparatively convenient, and this protection device uses comparatively conveniently.
Optionally, the positioning component comprises a mounting block fixed on the inner wall of the protection box, a positioning rod connected on the mounting block in a sliding way and an elastic piece arranged between the mounting block and the positioning rod; the adjusting handle is provided with a positioning hole for embedding the positioning rod, and the elastic piece applies elastic force to the positioning rod towards the direction of the adjusting handle; the positioning rod is provided with an adjusting rod, and the end part of the adjusting rod penetrates out of the protection box and is used for driving the positioning rod to slide.
Through adopting above-mentioned technical scheme, when using locating component to fix the adjustment handle, the locating lever tip inlays in the locating hole, and the elastic component applys the elasticity towards adjustment handle direction to the locating lever, reduces the problem that the locating lever breaks away from in the locating hole, promotes the stability to adjusting handle location, when needs rotate the adjustment handle, drives the locating lever through the regulation pole and slides for the locating lever tip deviate from in the locating hole, can release the fixed to the adjustment handle, and the operation is more convenient.
Optionally, two limiting rings are fixedly connected on the transfer tube, the clamping ring is positioned between the two limiting rings, and the two limiting rings are both abutted with the clamping ring.
Through adopting above-mentioned technical scheme, use spacing subassembly to carry out the clamping position's of transfer pipe under the state, the transfer pipe is difficult to appear the problem that relative clamping ring slided, promotes spacing subassembly to transfer pipe clamping fixed stability.
Optionally, a return spring is fixedly connected between the two clamping columns, the return spring is positioned in the protection box, and two ends of the return spring are fixedly connected to the two clamping columns respectively.
Through adopting above-mentioned technical scheme, when relieving spacing subassembly to the fixed of adapter, at first drive the locating lever and break away from the locating hole through adjusting the pole, at this moment, two grip posts rotate to the direction of keeping away from each other under reset spring's effect, later can adjust the position of grip post through the adjustment handle, promoted the convenience of operation.
Optionally, one end of the protection tube connected to the cage side plate is rotationally connected with a connecting ring, and the connecting ring is fixedly connected to the cage side plate; the end of the liquid passing pipe penetrates to the outer side of the cage, the end of the liquid passing pipe, which is located outside the cage, is provided with a force release assembly, the force release assembly comprises a connecting piece connected to the liquid passing pipe, a communicating pipe used for being connected with a liquid medicine storage container and a force release piece arranged between the connecting piece and the communicating pipe, the connecting piece is connected with the communicating pipe through the force release piece, and the connecting piece is rotationally connected with the force release piece.
Through adopting above-mentioned technical scheme, set up between logical liquid pipe and communicating pipe and let out the power subassembly, and connecting piece and let out the power piece and rotate and be connected, under monkey activity drive logical liquid pipe torsion's the circumstances, connecting piece and let out the power piece relative rotation, keep communicating pipe's stability, communicating pipe is comparatively stable with liquid medicine storage container connection promptly, reduces and twists reverse and cause the problem of pipeline jam because of monkey activity drive logical liquid pipe, keeps the patency that liquid medicine was carried.
Optionally, the force release piece comprises a shell and a sealing plug arranged in the shell, and one end of the shell is an opening; the connecting piece comprises two flat head needles and a joint arranged between the two flat head needles, wherein the end part of one flat head needle is inserted into the liquid through pipe and connected with the liquid through pipe, the end part of the other flat head needle far away from the joint penetrates through the sealing plug and is connected with the communicating pipe, and the flat head needle is rotationally connected with the sealing plug.
Through adopting above-mentioned technical scheme, it is comparatively convenient to the operation of being connected with communicating pipe to lead to the liquid pipe, is connected with two flat-headed needles through the joint, and in one of them flat-headed needle tip inserted the liquid pipe, another flat-headed needle inserted in the sealing plug and be connected with communicating pipe, can accomplish the installation of liquid pipe and communicating pipe, and the operation is comparatively convenient.
Optionally, the protection box (2) comprises a box body with an opening at one side and a cover body hinged on the box body, and the cover body and the box body are fixed through a lock catch.
Through adopting above-mentioned technical scheme, can be comparatively convenient operate the installation box inside, reduce the restriction that receives the space, promote the convenience that this protection device used.
In summary, the present application includes at least one of the following beneficial technical effects:
1. through the protective tube, one end of the protective tube is fixedly connected to the protective box, the other end of the protective tube is rotationally connected with the side plate of the cage, and in the experimental process, the monkey moves in the cage to drive the liquid passing tube and the protective tube to twist, the protective tube is rotationally connected with the side plate of the cage, so that twisting caused by the movement of the monkey can be eliminated more conveniently, the problem of blocking the liquid passing tube inside is reduced, and in the long-time use process, the problems of pipeline damage, liquid leakage and the like are not easy to occur, and the smooth and stable liquid medicine conveying is maintained;
2. through the limiting component, the switching pipe is positioned, so that the problems of shaking and deflection of the embedded pipe can be reduced, the stability of the embedded pipe is kept, and the operation of fixing the switching pipe by using the limiting component is convenient;
3. through the pressure relief assembly that sets up, can be more convenient realize leading to liquid pipe and liquid medicine storage container's connection, set up crew cut needle and sealing plug simultaneously and rotate and be connected, the torsion that the monkey activity of comparatively convenient elimination drove leading to liquid pipe production is to communicating pipe department transmission, keeps communicating pipe's stability, is connected with liquid medicine storage container more stable promptly, is difficult to appear leading to the liquid pipe to twist reverse the problem that causes the pipeline to block up, keeps the smoothness nature of liquid medicine transportation.
Drawings
FIG. 1 is a schematic view of a protective device according to an embodiment of the present application;
FIG. 2 is a schematic view of the connection structure of the protective tube and the cage;
FIG. 3 is a schematic view for showing a connection structure of a liquid passing pipe and an embedded pipe;
FIG. 4 is a schematic diagram of a structure for illustrating a force release assembly;
FIG. 5 is an enlarged schematic view of portion A of FIG. 3
FIG. 6 is a schematic diagram taken to illustrate the structure of the positioning assembly;
fig. 7 is an enlarged schematic view of the portion B in fig. 6.
Reference numerals illustrate: 1. a wearable device; 2. a protection box; 21. a communication hole; 3. a liquid-passing pipe, 31, a transfer pipe; 32. a limiting ring; 4. a protective tube; 41. a connecting column; 42. a connecting collar; 43. an adapter ring; 44. a connecting ring; 5. pre-burying a pipe; 6. a force release assembly; 61. a connecting piece; 611. a flat needle; 612. a joint; 62. a force release member; 621. a housing; 622. a sealing plug; 623. a connecting pipe is inserted; 63. a communicating pipe; 7. a limit component; 71. a clamping column; 72. a clamping ring; 73. an adjusting handle; 731. positioning holes; 74. a return spring; 8. a positioning assembly; 81. a mounting block; 811. a cavity; 82. a positioning rod; 83. an elastic member; 831. a baffle ring; 832. a positioning spring; 84. and (5) adjusting the rod.
Detailed Description
The present application is described in further detail below in conjunction with figures 1-7.
The embodiment of the application discloses a protection device of embedded pipeline of independent dosing of monkey. In the experimental process of the monkey, the wearing equipment 1 is worn on the monkey body, referring to fig. 1, 2 and 3, the protection device of the embedded pipeline comprises a protection box 2 fixed on the wearing equipment 1, a liquid through pipe 3 connected with the protection box 2 and a protection pipe 4 fixed outside the liquid through pipe 3, wherein the protection box 2 is arranged at the position of the wearing equipment 1 on the back of the monkey, one end of the liquid through pipe 3 penetrates into the protection box 2, an embedded pipe 5 in the monkey body also penetrates into the protection box 2, the liquid through pipe 3 is communicated with the embedded pipe 5 in the protection box 2, and the other end of the liquid through pipe 3 penetrates through a side plate of a cage where the monkey is positioned and is used for being connected with a storage container of liquid medicine so as to be used for subsequently conveying the liquid medicine into the monkey body; wherein lead to liquid pipe 3 and be the hose, protection pipe 4 be the plastic pipe, can play the effect to lead to liquid pipe 3 protection through protection pipe 4, simultaneously, protection pipe 4 can carry out the bending of a certain extent to reduce the influence to monkey's activity.
Referring to fig. 2 and 3, a connecting post 41 is fixedly connected to the end of the protection tube 4 facing the protection box 2, a connecting sleeve ring 42 is connected to the connecting post 41 in a threaded manner, the connecting sleeve ring 42 is connected with the protection box 2 in a threaded manner, and the liquid passing tube 3 penetrates into the protection box 2 from the inside of the connecting sleeve ring 42; the other end of the protection tube 4 is fixedly connected with a connecting column 41, an adapter ring 43 is connected to the connecting column 41 in a threaded manner, one end, far away from the middle part of the protection tube 4, of the adapter ring 43 is rotationally connected with a connecting ring 44, and the connecting ring 44 is connected to the side plate of the cage in a threaded manner, so that the protection tube 4 is rotationally connected with the side plate of the cage.
Referring to fig. 2 and 4, the end of the liquid passing tube 3 located outside the cage is provided with a force release assembly 6, and the force release assembly 6 includes a connection member 61 connected to the liquid passing tube 3, a force release member 62 provided on the connection member 61, and a communication pipe 63 connected to the force release member 62; the connecting piece 61 comprises two flat needles 611 and a joint 612 arranged between the two flat needles 611, the two flat needles 611 are respectively sleeved at two ends of the joint 612, and the needle heads of the two flat needles 611 face away from each other; the needle head of one flat head needle 611 is inserted into the liquid passing pipe 3 and communicated with the liquid passing pipe 3, and the needle head of the other flat head needle 611 is connected with the force release piece 62.
Referring to fig. 2 and 4, the force release member 62 includes a housing 621 and a sealing plug 622 provided in the housing 621, wherein the housing 621 is provided as an opening toward one end of the liquid passage 3, the end of the tack needle 611 penetrates the sealing plug 622, and the tack needle 611 is rotatably connected with the sealing plug 622; the end surface of the shell 621 far away from the opening is fixedly connected with a plug pipe 623, the plug pipe 623 is communicated with the inside of the shell 621, and the plug pipe 623 is also provided with a flat head needle 611; the end of the flat needle 611 penetrating the sealing plug 622 abuts against the insertion tube 623 at a position where it communicates with the inside of the housing 621, so that the flat needle 611 on the sealing plug 622 communicates with the insertion tube 623; the communicating pipe 63 is mounted on the flat head needle 611 on the insertion pipe 623, and the end of the corresponding flat head needle 611 is directly inserted into the communicating pipe 63; the force release member 62 is similar to the construction of a syringe in that the housing 621 is similar to a barrel, the sealing plug 622 is similar to a plunger, and the connecting tube 623 is similar to a needle hub at the end of the barrel.
When the monkey is subjected to experiments, the wearing equipment 1 is worn on the body of the monkey, then the connection of the pipelines is carried out, the protection pipe 4 is fixed on the protection box 2 through the adapter ring 43, the liquid through pipe 3 is connected with the embedded pipe 5 in the body of the monkey, then the other end of the protection pipe 4 is fixed on the side plate of the cage through the connecting ring 44, one end of the liquid through pipe 3 far away from the protection box 2 penetrates to the outer side of the cage, one flat head needle 611 on the joint 612 is inserted into the end part of the liquid through pipe 3, the other flat head needle 611 penetrates through the sealing plug 622 and is communicated with the inserting pipe 623, the communicating pipe 63 is arranged on the flat head needle 611 on the inserting pipe 623, and finally the communication of the liquid through pipe 63 and a storage container of liquid medicine can be completed, and the liquid medicine can be injected into the body of the monkey.
In the process of injecting liquid medicine into a monkey body and carrying out experiments, the monkey drives the protective tube 4 and the liquid-passing tube 3 to twist when moving in the cage, and one end of the protective tube 4 far away from the protective box 2 is rotationally connected with the cage side plate so as to release torsion force generated on the protective tube 4 in the moving process of the monkey and maintain the stability of the connecting positions of the two ends of the protective tube 4; in addition, the liquid tube 3 in the protection tube 4 rotates synchronously therewith, so that the flat head needle 611 and the sealing plug 622 rotate relatively, and the shell 621 is in a stable state, so that the stability of connection between the liquid tube 3 and the liquid medicine storage container is ensured, and the problem that the stability of pipeline connection is influenced due to torsion of the liquid tube 3 is reduced.
Referring to fig. 3 and 5, the end part of the liquid passing pipe 3 in the protection box 2 is connected with a switching pipe 31, and the end parts of the liquid passing pipe 3 and the embedded pipe 5 are sleeved at two ends of the switching pipe 31 at the same time, so that the connection between the liquid passing pipe 3 and the embedded pipe 5 is realized; when the connection operation is carried out, the liquid through pipe 3 and the embedded pipe 5 are directly sleeved at the two ends of the switching pipe 31 respectively, so that the operation is convenient; in addition, a limiting component 7 is further arranged in the protection box 2 and used for fixing the position of the transfer pipe 31 so as to reduce the phenomenon that the embedded pipe 5 is driven to twist and shake in the process of monkey movement and fix the position of the embedded pipe 5.
Referring to fig. 1 and 3, the protection box 2 includes a box body, an opening is formed on one side of the box body adjacent to a connection position of the protection pipe 4, a cover plate for closing the opening is arranged on the box body, and the cover plate is hinged with the box body and is fixed by a lock catch; the limiting component 7 is arranged on the cover plate of the protection box 2, and a communication hole 21 is correspondingly formed in the cover plate of the protection box 2; the limiting component 7 comprises two clamping columns 71 which are rotationally connected to the protection box 2, one end of each clamping column 71 is positioned in the communication hole 21 and is rotationally connected with the side wall of the communication hole 21, the other end of each clamping column 71 is positioned in the protection box 2, the end part of each clamping column 71 positioned in the protection box 2 is fixedly connected with a clamping ring 72, each clamping ring 72 is semicircular, the end part of each clamping column 71 is fixed on the outer wall of each clamping ring 72, and in the process of the opposite rotation of the two clamping columns 71, the two clamping rings 72 are matched and clamped on the transfer tube 31, so that the position of the transfer tube 31 is fixed; an adjusting handle 73 is fixedly connected to the end portion, far away from the clamping ring 72, of the clamping column 71, the position of the clamping ring 72 is adjusted through the adjusting handle 73, and a positioning assembly 8 used for fixing the position of the adjusting handle 73 is arranged in the protection box 2.
Referring to fig. 3, the two adjustment handles 73 are rotated in opposite directions such that the ends of the two adjustment handles 73 away from the corresponding clamping posts 71 are away from each other, driving the two clamping posts 71 to rotate to bring the two clamping rings 72 toward each other, and when the two adjustment handles 73 are rotated to a state in which one side located outside the protection box 2 is flush with the outer wall of the protection box 2, the two clamping rings 72 are just clamped on the adapter tube 31; a return spring 74 is fixedly connected between the two clamping columns 71, and applies elastic force to the two clamping columns 71 so that the two clamping columns 71 are far away from each other; the adjustment lever 73 protrudes toward the inside of the protection box 2 toward one side inside the protection box 2.
Referring to fig. 6 and 7, the two positioning assemblies 8 are respectively located at positions corresponding to the two adjusting handles 73 on the inner wall of the protection box 2, and include a mounting block 81 fixed on the protection box 2, a positioning rod 82 slidably connected to the mounting block 81, and an elastic member 83 disposed between the mounting block 81 and the positioning rod 82, wherein the elastic member 83 applies an elastic force to the positioning rod 82 towards the direction of the corresponding adjusting handle 73, and a positioning hole 731 for embedding the positioning rod 82 is formed in the adjusting handle 73; the elastic member 83 comprises a baffle ring 831 fixed on the positioning rod 82 and a positioning spring 832 sleeved on the positioning rod 82, specifically, a cavity 811 for sliding the baffle ring 831 is formed in the mounting block 81, the positioning spring 832 is positioned in the cavity 811, the positioning spring 832 is positioned at one side of the baffle ring 831 away from the adjusting handle 73, one end of the positioning spring 832 is fixedly connected with the side wall of the end part of the cavity 811, and the other end of the positioning spring 832 is fixedly connected on the baffle ring 831; the baffle ring 831 is fixedly connected with a regulating rod 84, the end part of the regulating rod 84 penetrates out of the protection box 2, and the regulating rod 84 is in sliding connection with the mounting block 81 and the protection box 2.
When the position of the transfer tube 31 is fixed by using the limiting assembly 7, the two adjusting handles 73 are directly rotated to drive the two clamping rings 72 to be clamped on the transfer ring 43, at the moment, the end parts of the positioning rods 82 are embedded in the positioning holes 731, the positions of the adjusting handles 73 are fixed, the clamping rings 72 are kept to fix the transfer tube 31, and the operation of fixing the transfer tube 31 is convenient; when the transfer tube 31 needs to be taken down, the end part of the positioning rod 82 is driven to slide out of the positioning hole 731 through the adjusting rod 84, the clamping columns 71 are mutually far away under the action of the return spring 74, the adjusting handle 73 is rotated to the outer side of the protection box 2 from the communication hole 21, the transfer tube 31 can be detached, meanwhile, the adjusting handle 73 can be conveniently operated, and the use convenience is improved.
Referring to fig. 5, two limiting rings 32 are fixedly connected to the adapter tube 31, the clamping ring 72 is located between the two limiting rings 32 in a state that the clamping ring 72 is clamped on the adapter tube 31, the two limiting rings 32 are all abutted to the clamping ring 72, the problem that the adapter tube 31 and the clamping ring 72 slide relatively is reduced, and the stability of fixing the adapter tube 31 is improved.
The implementation principle of the protection device for the monkey autonomous drug administration embedded pipeline is as follows: when the monkey is subjected to an autonomous drug administration experiment, one end of a protective tube 4 is connected to a protective box 2, a liquid passing tube 3 is connected with an embedded tube 5, and the position of a switching tube 31 is fixed through a limiting assembly 7 in the process of connecting the liquid passing tube 3 and the embedded tube 5; then the other end of the protection tube 4 is connected to the side plate of the cage, the protection tube 4 is rotationally connected with the side plate of the cage through a connecting ring 44, the end part of the liquid passing tube 3 penetrates to the outer side of the cage, the flat head needle 611 and the force release member 62 are arranged at the end part of the liquid passing tube 3, the force release member 62 is connected with the liquid medicine storage container through the communicating tube 63, and then the liquid medicine can be conveyed into the monkey body.
In the process of monkey movement, the protective tube 4 is driven to twist, the protective tube 4 is rotatably connected with the cage side plate through the arrangement, the twisting force of the protective tube 4 can be released, the phenomenon that blockage or liquid medicine is blocked due to pipeline twisting can be reduced, the liquid medicine is smoothly conveyed into the monkey body, and the problem that the connecting position of the protective tube 4 is damaged due to monkey movement is solved; in addition, a force release member 62 is provided between the liquid tube 3 and the communication tube 63, and when the liquid tube 3 rotates, the corresponding flat head needle 611 and the sealing plug 622 rotate relatively to keep the housing 621 in a fixed state, so that the stress generated by torsion of the liquid tube 3 can be eliminated more conveniently, the stability of connection between the liquid tube 3 and the liquid medicine storage container is maintained, and the problems of pipeline torsion blockage or liquid leakage are not easy to occur.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.
Claims (7)
1. Protection device of embedded pipeline of independently dosing of monkey, wearing on the monkey has wearing equipment (1), its characterized in that: the protection device of the embedded pipeline comprises a protection box (2) fixed on the wearing equipment (1), a liquid passing pipe (3) connected to the protection box (2) and a protection pipe (4) arranged outside the liquid passing pipe (3); one end of the protective tube (4) is fixedly connected to the protective box (2), and the other end of the protective tube is rotatably connected to a side plate of the cage where the monkey is positioned; one end of the protection tube (4) facing the protection box (2) is fixedly connected with a connecting column (41), the connecting column (41) is connected with a connecting lantern ring (42) in a threaded manner, and the connecting lantern ring (42) is connected with the protection box (2) in a threaded manner; the end part of the liquid passing pipe (3) penetrating into the protection box (2) is connected with an adapter pipe (31) for being connected with an embedded pipe (5) in the monkey body, and the liquid passing pipe (3) and the embedded pipe (5) are respectively sleeved at two ends of the adapter pipe (31); a limiting component (7) used for limiting the position of the switching tube (31) is arranged in the protection box (2); the limiting assembly (7) comprises two clamping columns (71) hinged to the protection box (2), clamping rings (72) are fixedly connected to the end parts of the clamping columns (71) located in the protection box (2), and the two clamping rings (72) are clamped on the adapter tube (31); an adjusting handle (73) is fixedly connected to one end, facing the outside of the protection box (2), of the clamping column (71), a communication hole (21) is formed in the protection box (2), one end, connected with the adjusting handle (73), of the clamping column (71) is located in the communication hole (21), and when the clamping ring (72) is clamped on the adapter tube (31), the adjusting handle (73) is located in the communication hole (21); the protection box (2) is provided with a positioning component (8) for fixing the adjusting handle (73).
2. The monkey autonomous dosing pre-buried pipeline protection device according to claim 1, wherein: the positioning assembly (8) comprises a mounting block (81) fixed on the inner wall of the protection box (2), a positioning rod (82) connected to the mounting block (81) in a sliding manner, and an elastic piece (83) arranged between the mounting block (81) and the positioning rod (82); the adjusting handle (73) is provided with a positioning hole (731) into which the positioning rod (82) is embedded, and the elastic piece (83) applies elastic force to the positioning rod (82) towards the direction of the adjusting handle (73); the positioning rod (82) is provided with an adjusting rod (84), and the end part of the adjusting rod (84) penetrates out of the protection box (2) and is used for driving the positioning rod (82) to slide.
3. The monkey autonomous dosing pre-buried pipeline protection device according to claim 1, wherein: two limiting rings (32) are fixedly connected to the transfer pipe (31), the clamping ring (72) is located between the two limiting rings (32), and the two limiting rings (32) are in butt joint with the clamping ring (72).
4. The monkey autonomous dosing pre-buried pipeline protection device according to claim 2, wherein: a return spring (74) is fixedly connected between the two clamping columns (71), the return spring (74) is positioned in the protection box (2), and two ends of the return spring are fixedly connected to the two clamping columns (71) respectively.
5. The monkey autonomous dosing pre-buried pipeline protection device according to claim 1, wherein: one end of the protective tube (4) connected to the side plate of the cage is rotationally connected with a connecting ring (44), and the connecting ring (44) is fixedly connected to the side plate of the cage; the end of the liquid passing pipe (3) penetrates to the outer side of the cage, the end of the liquid passing pipe (3) located outside the cage is provided with a force release assembly (6), the force release assembly (6) comprises a connecting piece (61) connected to the liquid passing pipe (3), a communicating pipe (63) used for being connected with a liquid medicine storage container and a force release piece (62) arranged between the connecting piece (61) and the communicating pipe (63), the connecting piece (61) is connected with the communicating pipe (63) through the force release piece (62), and the connecting piece (61) is rotationally connected with the force release piece (62).
6. The monkey is from protection device of dosing pre-buried pipeline according to claim 5, characterized in that: the force release piece (62) comprises a shell (621) and a sealing plug (622) arranged in the shell (621), and one end of the shell (621) is an opening; the connecting piece (61) comprises two flat needles (611) and a joint (612) arranged between the two flat needles (611), wherein the end part of one flat needle (611) is inserted into the liquid through pipe (3) to be connected with the liquid through pipe (3), the end part of the other flat needle (611) far away from the joint (612) penetrates through the sealing plug (622) to be connected with the communicating pipe (63), and the flat needle (611) is rotationally connected with the sealing plug (622).
7. The monkey autonomous dosing pre-buried pipeline protection device according to claim 1, wherein: the protection box (2) comprises a box body with an opening at one side and a cover body hinged on the box body, and the cover body and the box body are fixed through a lock catch.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110897267.5A CN113693774B (en) | 2021-08-05 | 2021-08-05 | Protection device for monkey autonomous administration embedded pipeline |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110897267.5A CN113693774B (en) | 2021-08-05 | 2021-08-05 | Protection device for monkey autonomous administration embedded pipeline |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998030254A2 (en) * | 1997-01-10 | 1998-07-16 | Emory University | Sample collection and drug delivery apparatus for freely-moving tethered laboratory animals |
| CN207721924U (en) * | 2017-06-15 | 2018-08-14 | 南方医科大学 | A kind of accurate drug delivery device of animal nerve Physiological Experiment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7665424B2 (en) * | 2005-07-06 | 2010-02-23 | Strategic Applications, Inc. | Harness interface conduit, tether line, and swivel for use in animals |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998030254A2 (en) * | 1997-01-10 | 1998-07-16 | Emory University | Sample collection and drug delivery apparatus for freely-moving tethered laboratory animals |
| CN207721924U (en) * | 2017-06-15 | 2018-08-14 | 南方医科大学 | A kind of accurate drug delivery device of animal nerve Physiological Experiment |
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