CN113693059A

CN113693059A - Specimen box suitable for animal viscera storage

Info

Publication number: CN113693059A
Application number: CN202111010854.4A
Authority: CN
Inventors: 沈链链; 杨健; 钟义红; 熊建平; 管强东; 刘艳青; 程洁
Original assignee: Nanjing Medical University
Current assignee: Nanjing Medical University
Priority date: 2021-08-31
Filing date: 2021-08-31
Publication date: 2021-11-26

Abstract

The embodiment of the invention provides a specimen box suitable for storing animal viscera, which belongs to the technical field of specimen storage and comprises the following components: a base plate; the accommodating body is provided with an accommodating cavity; a side hole is formed in the inner wall of the accommodating cavity and is communicated with the accommodating cavity and the outside; the end cover is detachably connected to the accommodating body; the connecting pipe is connected with and communicated with the side holes on the two accommodating bodies; and an adjustment assembly, the adjustment assembly comprising: an adjustment lever including a first lever body; a second rod body; the adjusting block corresponds to and is attached to the side hole in the inner wall of the accommodating cavity; the position of the first rod body relative to the end cover is adjustable, the first rod body is connected with the adjusting block, and the side hole in the accommodating body is opened through the adjusting block; the technical effects of reducing the injection times of the formaldehyde solution in the whole operation process and simplifying the operation process are achieved.

Description

Specimen box suitable for animal viscera storage

Technical Field

The invention relates to the technical field of specimen storage, in particular to a specimen box suitable for storing animal viscera.

Background

Many scientific studies are carried out by using experimental animals as models, and the experimental animals generally include mice, rats, rabbits, monkeys, etc., of which mice are the most commonly used. After the experiment is finished, most experimental animals are dissected, and the experimenter stores needed organs or conventional organs (such as heart, liver, spleen, lung, kidney and the like) in the formaldehyde solution for long-term storage, and can take out the organs for pathological examination when necessary in the future. The common storage mode at present is to store the viscera individually in sealable test tubes with the size suitable for the size of the viscera, and according to the relevant requirements, the formaldehyde solution: the ratio of visceral volume needs to be at least 5:1, small organs of an experimental animal, such as thyroid, adrenal gland, gall bladder and the like, can be intensively placed in a small test tube (such as the most commonly used EP tube with the volume of 1.5 ml), and large organs of brain, liver and the like need to be separately placed in a slightly large test tube (such as a test tube with the volume of 10 ml) or intensively placed in a larger test tube (such as a test tube with the volume of 50 ml), which brings certain trouble to the storage of samples according to animal numbers. Another method is to store all the internal organs of an experimental animal in a bottle or a specimen bag, which saves space and is beneficial to storage to a certain extent, but has great disadvantages: small organs such as adrenal gland and pituitary can be extruded and deformed by large organs, which has influence on future material collection and embedding, and can also influence the quality of pathological sections; and secondly, when only a certain specific visceral organ needs to be taken out in the future, all the visceral organs need to be fished out of the formaldehyde solution, and some small visceral organs can be adhered to the inside of the large visceral organs and are not easy to find, so that the risk of absorbing formaldehyde by experimenters is increased.

For convenience, if the organs of the experimental animal are stored in order according to the numbers, the best method is to place one organ in one container. However, if the containers are independent of one another, this means that the organ must be placed separately and the formaldehyde solution added separately each time. Therefore, the prior art has the problem that a specimen box which can be used for placing organs independently and can be used for injecting formaldehyde solution uniformly is lacked. In other words, there is a need for a cartridge that can adjust the amount of formalin to be injected at a time (since the volume of the container is large, the amount of formalin to be injected is large).

Disclosure of Invention

The embodiment of the application provides a specimen box suitable for storing animal viscera, which solves the technical problem that the viscera of an experimental animal cannot be stored orderly according to animal numbers in the prior art; the device achieves the technical effects of partitioning according to the visceral organs and greatly facilitating the storage and the taking of the visceral organs.

The embodiment of the application provides a specimen box suitable for animal internal organs is saved, specimen box suitable for animal internal organs is saved includes: a base plate; the accommodating body is arranged on the bottom plate and is provided with an accommodating cavity capable of accommodating visceral organs; a side hole is formed in the inner wall of the accommodating cavity, the side hole is a through hole, and the side hole is communicated with the accommodating cavity and the outside; the number of the accommodating bodies is at least two, and the two accommodating bodies are arranged at intervals; the end cover is detachably connected to the accommodating body, and the accommodating cavity is sealed through the end cover; the connecting pipe is hollow and is connected and communicated with the side holes on the two accommodating bodies, and the accommodating cavities of the two accommodating bodies are communicated through the connecting pipe; and an adjustment assembly, the adjustment assembly comprising: the adjusting rod comprises a first rod body, the first rod body penetrates through the end cover, part of the first rod body is positioned in the end cover, and the other part of the first rod body is positioned outside the end cover; a second rod body; the second rod body is positioned below the first rod body, connected with the first rod body and positioned in the accommodating cavity; the adjusting block is positioned in the accommodating cavity and connected with the second rod body; the adjusting block corresponds to and is attached to the side hole on the inner wall of the accommodating cavity; the position of the first rod body relative to the end cover is adjustable, the first rod body is connected with the adjusting block to be used on the adjusting block, and the side hole in the accommodating body is opened through the adjusting block.

Preferably, the accommodating body is fixedly connected with the bottom plate.

Preferably, the accommodating cavity in the accommodating body is provided with an upward opening, and the end cover is connected to the accommodating body from top to bottom.

Preferably, the side surface of the adjusting block transversely seals the accommodating cavity, the accommodating cavity is divided into a first accommodating cavity and a second accommodating cavity through the adjusting block, and the volume of the first accommodating cavity is adjustable through the adjusting block.

Preferably, a balance hole is formed in the adjusting block, the balance hole is a through hole, and two ends of the balance hole are respectively communicated with the first accommodating cavity and the second accommodating cavity.

Preferably, the side lines of the adjusting block relative to the two side surfaces of the first accommodating cavity and the second accommodating cavity are both designed to be chamfered.

Preferably, the first rod body is connected with the end cover in a sliding mode, and a locking device is further connected to the outer side portion, opposite to the end cover, of the first rod body.

Preferably, the specimen box suitable for storage of animal organs further comprises: the filter screen, the filter screen is fixed to be set up in the side opening or the connecting tube in holding chamber.

Preferably, the accommodating body and/or the end cap have a certain interval relative to the edge of the bottom plate, and the specimen box suitable for storing animal viscera further comprises: the cover plate is connected with the bottom plate to form an accommodating cavity for coating the accommodating body and the end cover.

Preferably, the cover plate comprises a cover plate side surface, and the cover plate side surface and the end cover or the accommodating body are clamped and fixed.

A method of using a cartridge, the method of using the cartridge comprising the steps of: according to the number of the viscera to be stored, the end covers of the corresponding accommodating cavities are taken down from the plurality of accommodating bodies, so that the accommodating cavities of the accommodating bodies are exposed; injecting formaldehyde solution into the accommodating body exposed out of one accommodating cavity, so that the formaldehyde solution is synchronously injected into the plurality of accommodating bodies, and the liquid level of each accommodating body is equal in height; after the formaldehyde solution is filled in the accommodating body, the viscera are placed in the accommodating body with the exposed accommodating cavity; after the viscera are placed in the accommodating body, the accommodating body and the end cover corresponding to the accommodating body are sealed and assembled into a whole; the position of the adjusting block in the accommodating body is adjusted through the first rod body of the adjusting assembly, so that excessive formaldehyde solution in the accommodating cavity is extruded out, or a space is provided for the formaldehyde solution flowing into the accommodating cavity.

Preferably, before the accommodating body and the end cover corresponding to the accommodating body are assembled into a whole in a sealing mode, the position state of the adjusting assembly connected with the end cover is adjusted, so that the adjusting block is close to the end cover.

One or more technical solutions in the embodiments of the present application have at least one or more of the following technical effects:

1. in the embodiment of the application, the bottom plate is provided with a plurality of accommodating bodies which are communicated through the connecting pipes to form a structural frame with the accommodating bodies communicated with each other, and the opening of the side holes in the accommodating bodies is controlled based on the adjusting assembly, so that the formaldehyde solution injected at one time can flow into the accommodating bodies; the technical problem that the visceral organs of experimental animals can not be stored orderly according to the animal numbers in the prior art is solved; the device achieves the technical effects of partitioning according to the visceral organs and greatly facilitating the storage and the taking of the visceral organs.

2. In the embodiment of the application, the requirement of the adjusting block for transversely sealing the accommodating cavity is met by further optimizing the size of the adjusting block, so that the accommodating cavity is divided into a first accommodating cavity and a second accommodating cavity; and adjust the volume of the first holding chamber that holds the internal organs through adjusting the mode of pole adjustment regulating block to reach the use amount of formalin in the control holding according to the actual size of internal organs, at the formalin volume: under the requirement that the volume ratio of the viscera at least reaches 5:1, the excessive use of the formaldehyde solution is avoided, and the preservation cost of the viscera is saved.

3. In this application embodiment, set up the balancing hole in the regulating block, based on the characteristics in first holding chamber of balancing hole intercommunication and second holding chamber, guarantee the in-process of regulating block up-and-down motion, atmospheric pressure balance between first holding chamber and the second holding chamber guarantees that the accommodation process of whole regulating block is laborsaving, and is smooth and easy, and reduces the resistance to compression requirement to the holding body, end cover. In addition, the regulating block has certain thickness to end has certain difference in height about making the balancing hole, and when the volume of the first holding chamber of two holding bodies is different (promptly two holding internal regulating block height is different), the little party in first holding chamber can compensate based on the difference in height of the balancing hole of the regulating block that it corresponds, guarantees that the liquid level in two holding bodies is in the state of flushing.

4. In the embodiment of the application, apron cooperation bottom plate constitutes a cladding chamber, and but apron side joint holding body or end cover to make the overall structure of this specimen box compact, do not rock, the resistance to compression tensile is favorable to the storage and the transportation of internal organs.

Drawings

FIG. 1 is a schematic axial view of a specimen box suitable for storing animal organs in an embodiment of the present application;

FIG. 2 is a schematic top view of a specimen box suitable for storing animal organs in an embodiment of the present application;

FIG. 3 is a schematic cross-sectional view of a specimen box suitable for storing animal organs in an embodiment of the present application;

fig. 4 is a schematic sectional structural diagram of a specimen box suitable for storing animal organs in the embodiment of the application when storing the organs;

FIG. 5 is a schematic cross-sectional view of a specimen box suitable for storing animal organs in the embodiment of the present application;

FIG. 6 is a schematic cross-sectional view of a specimen box suitable for storing animal organs in an embodiment of the present application;

FIG. 7 is a schematic cross-sectional view of another specimen box suitable for storing animal organs in an embodiment of the present application;

fig. 8 is a cross-sectional view schematically showing another modification of the connection pipe in the embodiment of the present application.

Reference numerals: 1. a base plate; 2. an accommodating body; 21. an accommodating cavity; 211. a first accommodating cavity; 212. a second accommodating cavity; 22. a side hole; 3. an end cap; 31. an end cap seal; 4. an adjustment assembly; 41. adjusting a rod; 411. a first rod body; 412. a second rod body; 42. an adjusting block; 422. a sealing strip; 43. a locking device; 5. a connecting pipe; 6. filtering with a screen; 7. a cover plate; 71. a cover plate side; 8. organs.

Detailed Description

The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects depicted, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings). In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present application and for simplicity in description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be considered as limiting the present application.

In this application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

The embodiment of the application provides a specimen box suitable for storing animal viscera, wherein a plurality of accommodating bodies 2 are arranged on a bottom plate 1, the accommodating bodies 2 are communicated through connecting pipes 5 to form a structural frame for mutual communication among the accommodating bodies 2, and opening and closing of side holes 22 on the accommodating bodies 2 are controlled based on an adjusting component 4, so that a formaldehyde solution injected at one time can flow into the accommodating bodies 2 through the connecting pipes 5; the problem that the amount of the formaldehyde solution injected into the container can not be adjusted at one time according to the volume of the container in the prior art is solved; the device can be divided into regions (numbered) according to the viscera, and the formaldehyde solution can be injected into the device at one time. Greatly facilitates the technical effects of storing and taking the viscera. It should be noted that the organ is not placed in formaldehyde for the ultimate purpose, but the slice is the ultimate purpose. The viscera can be taken out after at least 48 hours of formaldehyde to prepare pathological sections. Therefore, the ultimate meaning of the design is that after 48 hours or longer, when a certain organ of a certain mouse needs to be used, the organ can be conveniently obtained by numbering on the container; unlike the conventional storage method, a certain organ of a certain mouse cannot be found quickly.

In order to better understand the technical solution, the technical solution will be described in detail with reference to the drawings and the specific embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.

A specimen box suitable for storing animal viscera is disclosed, which is used for storing animal viscera with reference to the attached figures 1 and 2 of the specification. A specimen cassette suitable for animal viscera storage comprising: the device comprises a bottom plate 1, an accommodating body 2, an end cover 3, a connecting pipe 5, a filter screen 6, an adjusting component 4 and a cover plate 7; wherein, the holding body 2 is provided with a plurality ofly and is located bottom plate 1, based on connecting pipe 5 intercommunication between a plurality of holding bodies 2 to based on the connected state between a plurality of holding bodies 2 of adjusting part 4 control, reach the purpose that this device can once inject formaldehyde solution for a plurality of holding bodies 2. Of course, the device is used not only for mice but also for other animal specimens, such as rats, rabbits, monkeys, etc.

The injection of the formaldehyde solution is particularly required to be explained in that the formaldehyde solution is directly output from a device similar to a water dispenser at ordinary times, a switch is turned on, the formaldehyde flows into a specimen bag or a bottle, or the formaldehyde is sucked into a small tube by a pipette, and the risk of sucking the formaldehyde is high. Therefore, this design only need carry out the operation of filling of a formaldehyde before using, can accomplish to reduce the risk that the experimenter inhales formaldehyde (connect a hose on the formaldehyde bucket, can insert a formaldehyde of this equipment and fill the mouth, fill formaldehyde through the switch, have a little gas outlet in addition on equipment for the switch that the formaldehyde filled is closed at any time to the exhaust with observe the liquid level height. Combining the risks of the formaldehyde perfusion, the formaldehyde perfusion method is optimally designed to be that the formaldehyde is perfused in advance and then is put into the viscera (the quicker the viscera are separated, the better the formaldehyde is soaked); if the operation is not realized due to the consideration of other functions (for example, to reduce the risk of inhalation of experimenters or other reasons), the operation can also be performed by firstly placing organs and finally uniformly filling formaldehyde, which is beneficial to reducing the contact time of operators and formaldehyde solution when opening and closing the accommodating body 2.

The bottom plate 1, refer to the attached figure 2 in the specification, and the bottom plate 1 is a plate body and serves as a carrier of the accommodating body 2. It can be understood that the attached drawing 2 of the specification is a plan pattern diagram for placing the mouse viscera, and the accommodating bodies 2 are arranged on the bottom plate 1 according to the arrangement mode of the viscera 8 in the mouse body (namely, the shape frames of the mouse or other animals are arranged by a plurality of containers), and the storage positions of the viscera 8 are selected based on the actual physiological structure of the mouse (or other animals), so that under the condition that the labels are fuzzy or the visual angle is poor, the 8 types of the viscera stored in the accommodating bodies 2 can be rapidly determined.

The container 2, referred to in the description and attached to fig. 3, is used for containing the mouse's viscera 8. The accommodating body 2 is arranged on the bottom plate 1, and the accommodating body 2 is provided with an accommodating cavity 21 capable of accommodating the visceral organ 8; a side hole 22 (fig. 6) is arranged on the inner wall of the accommodating cavity 21, the side hole 22 is a through hole, and the side hole 22 is communicated with the accommodating cavity 21 and the outside; at least two accommodating bodies 2 are arranged, and the two accommodating bodies 2 are arranged at intervals; if the two containers 2 are two containers with different cross-sectional areas, after the formaldehyde solution is filled, the formaldehyde solution stored between the two containers 2 is different according to the liquid level of the two containers 2 with different cross-sectional areas, and then the containers 2 are selected and placed according to the volume of the viscera to be stored. It should be noted that the accommodating body 2 and the bottom plate 1 may be an integral body, and the accommodating body 2 and the bottom plate 1 may also be a separate structure fixedly connected. It can be understood that the receiving cavity 21 in the receiving body 2 is opened upward, and the end cap 3 is connected to the receiving body 2 from top to bottom.

The size of each of the receiving bodies 2 is designed according to the size of a normal organ in scientific research, and a label (indicating what organ is) is provided beside each of the receiving bodies. In addition, a plurality of containers 2 for special organs can be reserved for the experimenter to store some special organs or tumor tissues or special pathological tissues (abbreviated as unconventional organs) discovered accidentally in the anatomy. Of course, if the containing cavities of the conventional visceral organs are not used up, the non-conventional visceral organs can be used by selecting one containing cavity of the conventional visceral organs which is not used yet and has almost the same size, and only the label needs to be changed.

The end cap 3, refer to fig. 3 of the specification, is used for cooperating with the accommodating body 2 to construct an accommodating cavity 21. The end cap 3 is detachably connected to the accommodating body 2, such as by sliding or screwing.

The connecting pipe 5, referring to the attached fig. 1 and 3, is used for connecting the accommodating cavities 21 of two or more accommodating bodies 2. The connecting pipe 5 is hollow, the connecting pipe 5 is connected with and communicated with the side holes 22 on the two accommodating bodies 2, and the accommodating cavities 21 of the two accommodating bodies 2 are communicated through the connecting pipe 5. It will be understood that the connection tube 5 can be integral with the housing 2 or can be welded later. Of course, in order to facilitate the observation of the usage of the device, the accommodating body 2, the end cap 3 and the connecting pipe 5 are preferably made of transparent materials.

It should be noted that, referring to fig. 8 of the specification, the connecting pipe 5 may also be disposed at the bottom of the two containers 2, so that when the plurality of containers 2 are connected and combined with each other, the liquid below the liquid level of the connecting pipe 5 may also flow between all containers 2.

The filter screen 6, the filter screen 6 is fixed to be set up in the side opening 22 or the connecting pipe 5 of holding chamber 21, avoids the viscera 8 card in side opening 22 through filter screen 6, avoids the viscera 8 to get into in the connecting pipe 5.

The regulating assembly 4, referred to in the description in the attached figures 3-4, is used, on the one hand, to seal the lateral holes 22 of the containing body 2 and, on the other hand, to control the amount of formaldehyde solution inside the containing body 2 by squeezing the level of the container. The adjustment assembly 4 comprises: an adjustment lever 41, an adjustment block 42, and a locking device 43; wherein, the adjusting rod 41 is respectively connected with the adjusting block 42 and the locking device 43, the adjusting rod 41 can be locked on the end cover 3 based on the locking device 43, and when the end cover 3 is fixed on the upper end of the accommodating body 2, the height of the adjusting rod 41 is also limited.

The adjusting rod 41, the adjusting rod 41 includes a first rod 411 and a second rod 412, and preferably, the first rod 411 and the second rod 412 are upper and lower portions of a whole rod. The first rod 411 penetrates the end cap 3, and a part of the first rod 411 is located inside the end cap 3, and the other part is located outside the end cap 3. In one embodiment, the first rod 411 is slidably connected to the end cap 3, and a locking device 43 is further connected to an outer portion of the first rod 411 opposite to the end cap 3. The second rod 412 is located below the first rod 411, the second rod 412 is connected to the first rod 411, and the second rod 412 is located in the accommodating cavity 21.

The adjusting block 42 is positioned in the accommodating cavity 21, and the adjusting block 42 is connected with the second rod body 412; and the adjusting block 42 corresponds to and is attached to the side hole 22 on the inner wall of the accommodating cavity 21. Based on the position of the first rod 411 relative to the end cover 3 is adjustable, the first rod 411 acts on the adjusting block 42 in a linkage manner, and the adjusting block 42 can enable the side hole 22 on the accommodating body 2 to be opened or closed. It will be appreciated that the end cap 3 may be removed separately, or the adjustment assembly 4 may be lifted separately and the height of the adjustment assembly 4 fixed.

Based on the constructed adjusting component 4, the volume of the first accommodating cavity 211 in the accommodating body 2 can be adjusted at will when the accommodating body accommodates animal viscera, so as to accommodate animal viscera with different shapes and volumes. The liquid level of the formaldehyde does not need to be too high in small organs such as gall bladder, adrenal gland and the like or flat organs such as spleen, thymus and the like. The heart, the liver and the like are three-dimensional structures, and the liquid level of the required accommodating cavity is high.

More importantly, the liquid level of the first accommodating cavities 211 can be squeezed by lifting one adjusting block 42 among the plurality of mutually communicated first accommodating cavities 211. Because of the principle of the communicating vessels, the heights of the other regulating blocks 42 are controlled (the liquid level of the other first accommodating cavities 211 is adjusted, and the heights of the other regulating blocks 42 are adjusted in turn).

Further, referring to the attached drawing 6 of the specification, the sealing strip 422 is arranged on the side face of the adjusting block 42 in a surrounding mode, the sealing strip 422 is attached to the inner wall of the accommodating cavity 21, the material of the sealing strip 422 is selected, if the adjusting block 42 is made of metal, the sealing strip 422 is made of rubber, so that the adjusting block 42 has enough hardness to be connected with the adjusting rod 41 in a threaded mode under the condition that the adjusting block 42 can be sealed with the accommodating cavity 21. It will be appreciated that the sealing strip 422 may be provided in multiple layers in an up-down relationship on the adjustment block 42 to enhance the sealing effect; and when the two side sealing strips 422 are respectively positioned at the upper side and the lower side of the side hole 22, the amount of formaldehyde solution waste is reduced.

The cover plate 7, refer to fig. 7 of the specification, is used for making the appearance of the device smooth, and is convenient for stacking and storing. The cover plate 7 is connected with the bottom plate 1 in a bonding and clamping manner or a clamping manner by utilizing a clamp. And forms a containing cavity 21 for covering the containing body 2 and the end cover 3. The cover plate 7 comprises a cover plate side face 71, and the cover plate side face 71 is clamped and fixed with the end cover 3 or the accommodating body 2. It should be noted that, in the case of the cover plate 7, the accommodating body 2 and/or the end cap 3 are preferably spaced apart from the edge of the base plate 1, so as to facilitate the attachment and connection of the edges of the cover plate 7 and the base plate 1.

A method of using a cartridge, the method of using a cartridge comprising the steps of:

and S1, taking down the end covers 3 of the corresponding accommodating cavities from the accommodating bodies 2 according to the number of the viscera 8 required to be stored, and taking out all the adjusting blocks 42. If six organs 8 need to be stored, the end covers 3 on the corresponding six accommodating bodies 2 in the device are opened, so that the accommodating cavities of the six accommodating bodies 2 are exposed. The remaining unwanted container 2 lowers the regulating block 42 to the bottom to block the side hole 22. Then, the adjusting rod 41 is locked on the end cover 3 through the locking device 43, the end cover 3 is fixed on the accommodating body 2, and the height of the adjusting rod 41 is fixed, so that the adjusting block 42 is fixed at the bottom of the accommodating cavity, the side hole 22 is blocked, and the formaldehyde solution cannot enter the accommodating cavity of the accommodating body 2 which is not used through the connecting pipe 5.

S2, the exposed containers 2 are filled with formaldehyde solution, since the connecting pipes 5 are connected, the containers 2 are filled with formaldehyde solution at the same time, and the liquid level of each container 2 is equal to the height of the other container. It should be noted that, the inner surface or the outer surface of the accommodating body 2 may be provided with a scale mark, so as to fill the formaldehyde solution to a conventional liquid level based on the scale mark. The conventional level may be known based on past filling experience.

And S3, after the formaldehyde solution is filled in the accommodating body 2, placing the viscera 8 in the accommodating body 2 with the exposed accommodating cavity, and then continuously filling the formaldehyde solution until the liquid level is flush with the accommodating body 2.

S31, the adjusting blocks 42 in the containing cavities are flatly placed at the top of the liquid level, meanwhile, the locking device 43 of one idle containing cavity is released, the adjusting blocks 42 of the idle containing cavity are lifted upwards, the liquid level of the formaldehyde solution in the other containing cavities with the adjusting blocks 42 placed therein begins to descend, and the adjusting blocks 42 also descend along with the liquid level.

S4, the height of the adjusting block 42 in each accommodating cavity can be freely adjusted according to the size of the organ in each accommodating cavity, so that the volume of the first accommodating cavity 211 matches the volume of the organ 8 in the accommodating cavity. After the volume of each first receiving cavity 211 is adjusted, the receiving body 2 and the end cap 3 corresponding to the receiving body 2 need to be assembled into a whole, and the adjusting rod 41 needs to be locked to the end cap 3 by the locking device 43. And then continues to adjust the next first receiving cavity 211.

At this time, since the adjusting block 42 is immersed in the formaldehyde in the container 2, the part of the formaldehyde which is occupied by the adjusting block 42 is squeezed to flow into the other container 2 which is not covered, so that the liquid level of the formaldehyde in the other containers 2 is raised, and the height of the adjusting block 42 in the other containers 2 is raised due to the principle of the communicating vessel, and vice versa. Of course, if the height of the adjustment block 42 of the empty accommodation chamber is continuously raised, the height of the adjustment block 42 in the accommodation chamber in which each organ 8 is placed is raised or lowered by the principle of the communicating vessel. That is, the volume of the other first receiving cavities 211 can be uniformly adjusted by adjusting the height of the adjusting block 42 of the empty receiving cavity, or the volume of each first receiving cavity 211 can be adjusted by adjusting the height of the adjusting block 42 in each receiving cavity alone.

S5, after adjusting each first receiving cavity 211, the receiving body 2 and the end cap 3 corresponding to the receiving body 2 are assembled into a whole, and the adjusting rod 41 is locked to the end cap 3 by the locking device 43. It is of course also possible to unlock or to directly remove the end cap 3. But at this time, the adjustment rod 41 of the empty accommodation chamber must be locked to the end cap 3 by the locking device 43.

Namely, the height of the adjusting block 42 in the first accommodating cavity 211 can be locked in two ways, one is to lock the height of the adjusting rod 41 in each first accommodating cavity 211, and at this time, the height of the adjusting rod 41 in the free accommodating cavity is not locked. The other is to lock the height of the adjusting rod adjusting block 42 of the idle accommodating cavity only, so that the height of each adjusting block 42 of the first accommodating cavity 211 is locked in a phase-changing manner through the principle of a communicator.

Certainly, a special accommodating cavity can be arranged to be the idle accommodating cavity, the connecting pipe 5 on the idle accommodating cavity is provided with a switch, so that after the other accommodating cavities are adjusted, the switch on the connecting pipe 5 can be closed, the idle accommodating cavity is isolated from the communicating vessel, and the adjusting rod 41 of the idle accommodating cavity at the moment does not need to be locked.

And S6, covering the cover plate on the bottom plate.

And S7, when the viscera needs to be taken out, the locking of the adjusting rod 41 in the needed accommodating cavity is released, the adjusting block 42 and the idle accommodating cavity of the unlocked accommodating cavity are communicated with each other according to the principle of a communicating vessel, the height of the 2 adjusting blocks 42 can be arbitrarily lifted at the moment until the adjusting block 42 is taken out, and the viscera in the accommodating cavity is exposed at the moment.

The technical effects are as follows:

1. in the embodiment of the application, the bottom plate is provided with a plurality of accommodating bodies which are communicated through the connecting pipes to form a structural frame with the accommodating bodies communicated with each other, and the opening of the side holes in the accommodating bodies is controlled based on the adjusting assembly, so that the formaldehyde solution injected at one time can flow into the accommodating bodies; the technical problems that in the prior art, a plurality of visceral organs of a mouse need to be stored independently, and proper amounts of formaldehyde solution need to be injected into a plurality of test tubes respectively in the whole operation process are solved; the technical effects of reducing the injection times of the formaldehyde solution in the whole operation process and simplifying the operation process are achieved.

3. In the embodiment of the application, apron cooperation bottom plate constitutes a cladding chamber, and but apron side joint holding body or end cover to make the overall structure of this specimen box compact, do not rock, the resistance to compression tensile is favorable to the storage and the transportation of internal organs.

While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.

It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims

1. A cartridge adapted for animal viscera storage, the cartridge comprising:

a base plate;

the accommodating body is arranged on the bottom plate and is provided with an accommodating cavity capable of accommodating visceral organs; a side hole is formed in the inner wall of the accommodating cavity, the side hole is a through hole, and the side hole is communicated with the accommodating cavity and the outside; the number of the accommodating bodies is at least two, and the two accommodating bodies are arranged at intervals;

the end cover is detachably connected to the accommodating body, and the accommodating cavity is sealed through the end cover;

the connecting pipe is hollow and is connected and communicated with the side holes on the two accommodating bodies, and the accommodating cavities of the two accommodating bodies are communicated through the connecting pipe; and

an adjustment assembly, the adjustment assembly comprising:

an adjustment lever, the adjustment lever comprising

The first rod body penetrates through the end cover, one part of the first rod body is positioned in the end cover, and the other part of the first rod body is positioned outside the end cover;

a second rod body; the second rod body is positioned below the first rod body, connected with the first rod body and positioned in the accommodating cavity;

the adjusting block is positioned in the accommodating cavity and connected with the second rod body; the adjusting block corresponds to and is attached to the side hole on the inner wall of the accommodating cavity;

the position of the first rod body relative to the end cover is adjustable, the first rod body is connected with the adjusting block to be used on the adjusting block, and the side hole in the accommodating body is opened through the adjusting block.

2. The specimen box suitable for storage of animal organs as claimed in claim 1, wherein the container and the bottom plate are fixedly connected.

3. The specimen box suitable for storing animal organs as claimed in claim 1, wherein the cavity in the accommodating body is open upward, and the end cap is connected to the accommodating body from top to bottom.

4. The specimen box suitable for storage of animal viscera according to claim 1, wherein the accommodating cavity is transversely sealed by the side surface of the adjusting block, and is divided into a first accommodating cavity and a second accommodating cavity by the adjusting block, and the volume of the first accommodating cavity is adjustable by the adjusting block.

5. The specimen box suitable for animal viscera storage according to claim 4, wherein a balance hole is arranged inside the adjusting block, the balance hole is a through hole, and two ends of the balance hole are respectively communicated with the first accommodating cavity and the second accommodating cavity.

6. The specimen box suitable for animal viscera storage as claimed in claim 4, wherein the edge lines of the adjusting block relative to the two side surfaces of the first accommodating cavity and the second accommodating cavity are both in chamfer design.

7. The cartridge adapted for animal viscera storage of claim 1, further comprising:

the filter screen, the filter screen is fixed to be set up in the side opening or the connecting tube in holding chamber.

8. The specimen box suitable for animal viscera storage of claim 1, wherein the accommodating body and/or the end cap have a certain interval relative to the edge of the bottom plate, and the specimen box suitable for animal viscera storage further comprises:

the cover plate is connected with the bottom plate to form an accommodating cavity for coating the accommodating body and the end cover.

9. A method of using a cartridge, the method comprising:

according to the number of the viscera to be stored, the end covers of the corresponding accommodating cavities are taken down from the plurality of accommodating bodies, so that the accommodating cavities of the accommodating bodies are exposed;

injecting formaldehyde solution into the accommodating body exposed out of one accommodating cavity, so that the formaldehyde solution is synchronously injected into the plurality of accommodating bodies, and the liquid level of each accommodating body is equal in height;

after the formaldehyde solution is filled in the accommodating body, the viscera are placed in the accommodating body with the exposed accommodating cavity;

after the viscera are placed in the accommodating body, the accommodating body and the end cover corresponding to the accommodating body are sealed and assembled into a whole;

the position of the adjusting block in the accommodating body is adjusted through the first rod body of the adjusting assembly, so that excessive formaldehyde solution in the accommodating cavity is extruded out, or a space is provided for the formaldehyde solution flowing into the accommodating cavity.

10. The method of claim 9, wherein the adjusting member coupled to the end cap is adjusted to a position such that the adjusting block is adjacent to the end cap before the receiving member and the end cap corresponding to the receiving member are sealingly assembled together.