CN1136906C - Medicine for preventing and treating myopia and amlyopia - Google Patents

Abstract

The present invention relates to a medicine for preventing and treating myopia and hypermetropia, which is formed by taking kudzuvine root, tangshen, milkvetch root, angelica, hemlock parsley, atractylodes rhizome, dahurian angelica, oyster shell, nacre, fineleaf schizonepeta herb, ledebouriella root, thinleaf milkwort root, grassleaf sweetflag rhizome, semen cuscutae, plantain seed, common clubmoss herb, poria from yunnan of China, kadsura pepper stem, scorpion, white tribulus and radix glycyrrhiza as raw materials which are prepared into medicines of various preparation formulations according to the conventional method. The medicine has the advantages of good treating effect, high cure rate, low cost and little possibility of relapse, and is particularly suitable for preventing and treating myopia and hypermetropia for middle school students and primary school students.

Description

The medicine of prevention and treatment myopia, amblyopia

(1) technical field

The present invention relates to the medicine of a kind of prevention and treatment myopia, amblyopia, specifically it is to be the Chinese patent medicine of feedstock production with the Chinese herbal medicine, belongs to pharmaceutical.

(2) background technology

Myopia, amblyopia is that a kind of cause of disease is many, one of many and puncture disease of being difficult to cure of type, its sickness rate has the trend that rises year by year in recent years, especially the teenager sickness rate is more obvious, and does not still have medicine preferably at present on Therapeutic Method, most wearing spectacles that adopt, the health-care appliance treatment, under serious situation, adopt operative treatment, the OO eye-protection instrument of Xiao Shouing in the market, though health care such as physiotherapeutic glasses for myopia instrument is some effect, but can not cure, and easily recur and increase the weight of the state of an illness, medicine that also has such as medicine for treating myopia, not only price height, and medicine is placed on the eye massage, use trouble, drug effect is not in place, and treatment time is long, the operative treatment sequela is more, laser therapy vision instability, and the surgical laser taboo is more, and the age is entirely after 18 years old.

(3) summary of the invention

Purpose of the present invention is the shortcoming and deficiency in order to overcome above-mentioned prior art just, and provides a kind of according to the cause of disease state of an illness, the medicine of pointed prevention and treatment myopia, amblyopia, thus can remove patient's misery, improve physically and mentally healthy quality.

The objective of the invention is to realize by following technical proposal:

The medicine of a kind of prevention and treatment myopia, amblyopia is characterized in that it is the medicament of being made according to a conventional method by the raw material of following weight proportioning: the windproof 8-10 part of root of kudzu vine 6-8 part Radix Codonopsis 8-12 part Radix Astragali 10-15 part Radix Angelicae Sinensis 8-10 part Ligusticum wallichii 6-8 part rhizoma atractylodis 15-20 part root of Dahurain angelica 8-10 part oyster 30-40 part mother-of-pearl 30-40 part schizonepeta 10-12 part polygala root 10-12 part grass-leaved sweetflag 10-15 part seed of Chinese dodder 20-25 part plantain seed 30-35 part lycopodium calvatum 20-25 part cloud Siberian cocklebur 10-15 part caulis piperis futokadsurae 15-20 part scorpio 6-8 part tribulus terrestris 20-25 part Radix Glycyrrhizae 3-5 part.

Described medicament is a said dosage form on any pharmaceutics; Described medicament is powder, tablet, pill.

Medicine of the present invention is according to theory of Chinese medical science and through for many years clinical practice, checking repeatedly, the prescription of further observing and establishing, in clinical research for many years, the reason of myopia is divided multiple, wherein 80% patient is with optical fundus puncture disease, be mainly myopia and merge the old optic neuritis, have and suffer from the myopia that the optic neuritis malpractice causes earlier, myopia back asthenopia is earlier also arranged, the optic neuritis that flu causes, both interact, the myopia that next causes for other reasons, its reason is congenital heredity and bad habit, the transition of requiring mental skill, aqueous humor increases, chronic rhinitis, lack the pathologic myopia that nutrition etc. causes puerperal, find that also the myope sends out the inspection zinc deficiency and various trace elements all is starkly lower than the normal person, send out copper and send out the ferrum disorder, most of teenager extends the conus that cause by the eyeball rear wall in the period of development more than 95%, the optic disc obscure boundary, optic disc periphery venation, neurodeatrophia, the diopter of eye also changes with growth promoter, and that structure pathological changes of clinical patients whole body and eye can both cause adolescent myopia, as untimely treatment, will develop high myopia 4-5, or pigmentation or shop stone sample degeneration then appearred after 10 years, in addition, and along with the growth of axis oculi, the eyeball rear wall extends back, make retina, choroid is subjected to traction to form progressive injury and atrophic changes, and is leopard stricture of vagina optical fundus in early days, comus, it is oblique to look nipple, annular maculae atrophicae around the nipple, the later stage tunica uvea is swollen, vitreous degeneration, lacquer splits the infringement of sample stricture of vagina, serious optical fundus infringement such as Fuchs speckle causes punctum luteum hemorrhage, intercurrent diseases such as macular hole and detachment of retina at last, vision is seriously lost, the present invention is desirable opportunity with the early prevention and treatment, by the organic conception of the theory of TCM according to theory of Chinese medical science.It is clinical that dialectical opinion is controlled guidance.Point out that according to " Ling Shu Miraculous Pivot or Divine Axis, big puzzled opinion " " the essence of five ZANG-organs and six FU-organs gas, annotate on all in order and smart for it " and " Ling Shu Miraculous Pivot or Divine Axis, cacosplanchnia shape " point out " twelve regular channels 365 networks, its vim and vigour are all gone up in face and walked the sky key, walk order on its vivid YANG QI and essence for it ".Therefore the normal smart functional activities of the body fluid blood of vital organs of the human body function enriches, and order gets institute and supports that then manner is abundant, and according to the mirror all things on earth, resolution is multicolored, and clinical manifestation myopia does not have significant discomfort in the period of development.

Modern medicine study shows, do not have organic disease on inspection and corrects defects of vision normally that the person is amblyopia, and the cause of disease of amblyopia comes from the infringement visual center, and retrobulbar neuritis, Nervous and Mental Factors, scaring, brain injury can both be damaged nervus centralis and form amblyopia.

In sum, start with from the pathogenic factor of myopia, amblyopia, physiological and pathological in conjunction with eye has been selected medicine of the present invention, its effect is as follows: in the side: Radix Codonopsis, the Radix Astragali, Rhizoma Atractylodis, Radix Glycyrrhizae have invigorating the spleen and replenishing QI, the spleen strengthening and damp drying, eye muscle is shunk in excitement, increases rigidity of ocular wall and promotes microcirculation, accelerating its microcirculation forms, anti-hypoxia promotes DNA synthetic, contains each seed amino acid again simultaneously and carries out the nutrition the spleen strengthening and damp drying, each histiocyte of eyeball is expanded to disappear, recover normal structure and increase muscular strength, simultaneously again can antiviral, antibacterium.Radix Angelicae Sinensis, Rhizoma Chuanxiong is with invigorating blood circulation, enrich blood, nourish blood, the effect of removing blood stasis to reduce swelling, Radix Angelicae Sinensis spleen reinforcing blood-nourishing blood-generating, Rhizoma Chuanxiong is gone into liver and is walked gas in the blood, two medicine complementations, increase the merit of blood circulation promoting and enriching, Radix Angelicae Sinensis, Rhizoma Chuanxiong and Qi-tonifying drug produce complementation again, Radix Puerariae can improve the optical fundus microcirculation, spasmolytic, granulation promoting, Herba Schizonepetae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Concha Margaritifera, Scorpio, Caulis Piperis Kadsurae, Herba Lycopodii, Fructus Atriplicis Sibiricae has the excitement of the optic nerve of stimulation, the mediation eyeball, the Zu Zhi More active cell that stagnates, relaxing muscles and tendons and activating QI and blood in the collateral, remove the fatigue of brain and eye, increase various nutritions, contain a large amount of trace element zincs of a large amount of calcareous and Scorpios, Radix Polygalae as Concha Margaritifera, Rhizoma Acori Graminei, Poria, Radix Glycyrrhizae has the reinforcing the heart Fructus Alpiniae Oxyphyllae, tranquillizing the mind by relieving convulsion, sharp eye key is a monarch drug of the present invention.Semen Cuscutae, Semen Plantaginis, invigorating the liver and kidney, the nourishing diuretic that makes eye bright contains a large amount of vitamin A, the eyeball granulation promoting is increased look to coordinate each function of organization of eyeball.

The side has reinforcing the heart QI invigorating, tranquilizing the mind, tonifying liver, kidney, spleen reinforcing benefit blood entirely, muscle granulation promoting, Shujin system network, recovery visual center function increase the effect of looking by force.

Clinical report:

1, data and method

1.1 clinical data

Primary disease is the clinic case of 1987-2000, treatment total number of persons 250 examples, male's 120 examples wherein, women's 130 examples, simple myopia 130 examples, near-sighted with amblyope 90 examples, simple property amblyopia 30 examples, nearly amblyopia 205 examples of eyes, simple eye nearly amblyopia 15 examples, simple amblyopia 26 examples of eyes, simple eye simple property amblyopia 4 examples are worn mirror 210 examples, do not wear mirror 40 examples, check: diopter be-1.20D--5.50D 3 examples-6.00D, and closely the amblyope vision is minimum 0.02, amblyopia Visual power minimum 0.01, the simple myopia vision can be corrected, myopia companion's amblyopia, a vision correction part, amblyope can not be corrected.

1.2 Therapeutic Method

Adopt conventional method to carry out decocting three times medicine of the present invention, gained extracts medicinal liquid and is used for oral, patient below 10 years old, per two days potions, service once every day sooner or later, except the amblyopia, adult's potion every day, sooner or later respectively once, simple amblyope 20 days was a course of treatment, had a rest and obeyed second course of treatment after three days again.After the recovery from illness, check in every month was once obeyed two doses in every month again, adhered to 1 year, consolidated curative effect, was difficult for recurrence.

1.3 criterion of therapeutical effect:

The course of disease is short, and the optical fundus changes lighter nearly amblyope, takes medicine in 2 courses of treatment, and Visual power reaches 1.5, and it is normal that recover on the optical fundus.The course of disease is long, and the optical fundus changed in heavier 4 courses of treatment of taking medicine, and the optical fundus tremulous pulse is agitated normally, and vein recovers normal no sections and refluxes, and the optic disc color and luster is normal, nethike embrane, macula lutea, blood supply are normal, and Visual power reaches 1.2-1.5 and fully recovers;

It is effective that treatment back vision increases the 4-6 behavior.

After the treatment, vision no change or growth 1-2 are capable, for invalid.

The 1-4 therapeutic outcome:

Cure 90 examples 1 course of treatment, cure 120 examples 2 courses of treatment, cure 37 examples 3-4 the course of treatment, effective 3 examples, total effective rate 100%.

Typical case's case history:

1, summer so-and-so, woman, 12 years old student, hypoevolutism is an amblyopia through higher level's hospital diagnosis since the childhood, and binocular vision is 0.1, grow not goodly, it is unstable to walk, and goes annual summer vacation Beijing treatment through optometry, join mirror, acupuncture, multi-treatments such as the qigong, vision can reach about 0.8 sometimes, but the back vision of going to school is reduced to 0.1-0.3 again, detects through my section's outpatient service, distant vision is 0.3 (two), near vision 0.2 (two), and optic disc border, optical fundus is clear, color is light, the nethike embrane color is light, blood vessel is thin, the reflective disperse of reflective enhancing central fovea, the complexion heavy curtain is white, dull-looking, color of the lip is light white, and lassitude is tired unable, light red tongue is white, slight tooth seal, thready pulse without strength, diet is depressed, and is particular about food, takes medicine of the present invention, be eye behaviour, regulate hyperopia and myopia, through 30 days medication treatment, hyperopia and myopia were brought up to 1.2 (two), the new term begins, and medication 5 days, prevention of recurrence are continued in the back.Every year, checking eyesight was 1.2-1.5 (two) later on, and vision remains unchanged so far.

2, Zhang, the woman, 15 years old students binocular vision on inspection are 0.1, and there is the 3-4mm conus optic disc below in optical fundus, and nethike embrane macular area color is dark, the reflective disperse of central fovea, body development is normal, through taking Chinese medicine of the present invention after 35 days, detects distant vision to 1.5 (two), check in continuous 3 years, vision still remains unchanged.

3, Lee so-and-so, 17 years old student of woman, myopia was joined mirror-3.00D in 5 years, on inspection, eyes distant vision 0.1, near vision 0.6-0.8, leopard stricture of vagina optical fundus, optic disc Nie below, comus 4-5mm, optic disc dwindles obscure boundary, and the nethike embrane color is dark, the macular area color is dark, the reflective disappearance in center, dull-looking, happiness blink, healthy general, took Chinese medicine of the present invention 20 days, distant vision 1.5 (two), nearly 1.5 (two), after take the check of continuous 3 years of all Chinese medicine again, vision keeps 1.2-1.5 (two) to be engaged in microcomputer work now.

4, Lee so-and-so, man, 15 years old student, caligation, distant vision 0.4 (two) near vision 0.5 (two) optical fundus optic disc is less than normal person's 1/2nd on inspection to belong to the innate deficiency amblyopia, and optic disc nethike embrane vascular bending is thinner, the macula lutea color is light, the reflective disperse in center, dull-looking, the complexion health is general, took Chinese medicine of the present invention 15 days, hyperopia and myopia 1.5 (two) are taken again and were consolidated curative effect in two days, do not send out so far.

5, Lee so-and-so, woman, 23 years old, the specialist of raising chickens, because of Dai Jingyi causes the mist sense, blurring of vision influences the quality of raising chickens, and checks, near vision 1.0, distant vision 0.3, optical fundus optic disc obscure boundary, comus 3mm, the nethike embrane color is dark, the reflective disperse in center, and complexion is normal, and is healthy, obey 30 doses of this medicines, the next day check that vision improves gradually, vision eyes 1.0, check in 1 year, vision still keeps 1.0, so far not recurrence.This patient suffers from myopia behind the optic neuritis earlier.

6, Zhang, the man, 12 years old student, the patient is from little right eye amblyopia, through the large hospital treatment, poor effect, vision is 0.05 after testing, left vision is a hypermetropia 1.5, myopia 1.2, optic disc nethike embrane macula lutea at the bottom of the right eye, color and luster is light slightly, the reflective existence in right eye center, other are normal, take 35 doses of this medicines, 0.5, the second year phase in summer vacation of vision still keeps 0.5, continues to take 35 doses, existing vision reaches 1.2, after take a week again, not recurrence in 3 years.

7, Yang, woman, 25 years old, the cotton spinning workman finds blurring of vision 6 months puerperal, the hypermetropia 0.3 that has an eyesight test, myopia 0.5, the optometry part can be corrected, optical fundus, optic disc, nethike embrane color slightly are light, the reflective existence in center, dull-looking, the complexion heavy curtain is white, take a week behind this medicine, it is normal that recover on the optical fundus, hyperopia and myopia eyes 1.5.

Owing to take technique scheme, make the technology of the present invention compared with the prior art have following advantage and effect:

(a) adopting Chinese herbal medicine is raw material, makes the medicine of different dosage form, does not contain any additives;

(b) this medicine cost is low, and therapeutic effect is good, and cure rate height, and short treating period are without any side effects;

(c) to teen-age myopia, amblyopia has good treatment and preventive effect;

(d) applied widely, all can reach ideal therapeutic effect to all types of myopia, amblyopia treatment:

1, below diopter-6.00D, vision is more than 0.01 below 25 years old the age, and vision can be corrected, and part is corrected and maybe can not be corrected, and comus 3-5mm and the atrophy of ring network channels appear in the optical fundus;

2, the myopia that is caused by the old optic neuritis, optical fundus optic disc boundary member disappear or complete obiteration, and the severe patient center is gloomy, and tremulous pulse rotates unable, and vein increases thick bending, and sections refluxes, and nethike embrane macular area color is dark, the reflective disperse in center, and vision correction is incomplete;

3, optic disc is grown less than normal person's 1/2nd, vascular bending and thin, and vision can not be corrected or part is corrected;

4, optical fundus optic disc nethike embrane, macula lutea, center are reflective all normal, and the vision extreme difference can not be corrected;

5, after head and the eye wound, CT examination does not have the fracture of clot and cranial nerve or head operation back clot and eliminates clean vision and can correct maybe and can not correct;

6, within 1 year puerperal, the optic disc color is light, and vision can be corrected or part is corrected;

7, intraocular pressure higher or slightly high myopia or amblyopia that causes in the normal range of being everlasting, the optic disc color is light, and vision correction is incomplete;

8, earlier by chronic rhinitis myopia then, optical fundus vitreous opacity, blood vessel increase slightly, and nethike embrane macula lutea color is dark, and the most of rectification of vision is not complete;

In addition, send out inspection, zinc deficiency, calcium deficiency, trace element disorders such as copper, ferrum, slit lamp examination, lenticular opacity or slight muddy, retina, macula lutea portion hyporrhea appear in part.

(4) specific embodiment

Embodiment 1, get Radix Puerariae 6g, Radix Codonopsis 12g, Radix Astragali 10g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 6g, Rhizoma Atractylodis 15g, Radix Angelicae Dahuricae 10g, Concha Ostreae 30g, Concha Margaritifera 40g, Herba Schizonepetae 10g, Radix Saposhnikoviae 8g, Radix Polygalae 12g, Rhizoma Acori Graminei 10g, Semen Cuscutae 25g, Semen Plantaginis 30g, Herba Lycopodii 20g, Poria 15g, Caulis Piperis Kadsurae 20g, Scorpio 6g, Fructus Atriplicis Sibiricae 25g, Radix Glycyrrhizae 3g receives said medicine and decocts the powder process of extracting solution drying according to a conventional method, makes powder.

Embodiment 2, get Radix Puerariae 8g, Radix Codonopsis 8g, Radix Astragali 15g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 8g, Rhizoma Atractylodis 20g, Radix Angelicae Dahuricae 8g, Concha Ostreae 40g, Concha Margaritifera 30g, Herba Schizonepetae 12g, Radix Saposhnikoviae 10g, Radix Polygalae 10g, Rhizoma Acori Graminei 15g, Semen Cuscutae 20g, Semen Plantaginis 35g, Herba Lycopodii 25g, Poria 10g, Caulis Piperis Kadsurae 15g, Scorpio 8g, Fructus Atriplicis Sibiricae 20g, Radix Glycyrrhizae 5g receives said medicine and decocts the powder process of extracting solution drying according to a conventional method, makes tablet or pill.

Claims (1)

1, a kind of prevention and treatment myopia, the medicine of amblyopia is characterized in that it is the medicament of being made according to a conventional method by the following weight proportion raw material: Radix Puerariae 6-8 part Radix Codonopsis 8-12 part Radix Astragali 10-15 part Radix Angelicae Sinensis 8-10 part Rhizoma Chuanxiong 6-8 part Rhizoma Atractylodis 15-20 part Radix Angelicae Dahuricae 8-10 part Concha Ostreae 30-40 part Concha Margaritifera 30-40 part Herba Schizonepetae 10-12 part Radix Saposhnikoviae 8-10 part Radix Polygalae 10-12 part Rhizoma Acori Graminei 10-15 part Semen Cuscutae 20-25 part Semen Plantaginis 30-35 part Herba Lycopodii 20-25 part Poria 10-15 part Caulis Piperis Kadsurae 15-20 part Scorpio 6-8 part Fructus Atriplicis Sibiricae 20-25 part Radix Glycyrrhizae 3-5 part.