CN113648267A - 一种水刺/静电纺丝纳米纤维面膜及制备方法 - Google Patents
一种水刺/静电纺丝纳米纤维面膜及制备方法 Download PDFInfo
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Abstract
本发明涉及一种水刺/静电纺丝纳米纤维面膜及制备方法，所述面膜依次包括，面膜基布、含营养液的静电纺纤维；其中含营养液的静电纺纤维以含骨胶原蛋白肽粉、增稠剂、白附子提取物、透明质酸、羧甲基纤维素钠、芦荟提取液、甘油、丁二醇、水的原料，通过静电纺获得。本发明相较于现有技术配方，产品有效性和安全性更高、保湿效果好、可提高人体吸收、增加表皮修复速度、促进伤口愈合。
Description
技术领域
本发明属于面膜及其制备领域，特别涉及一种水刺/静电纺丝纳米纤维面膜及制备方法。
背景技术
静电纺丝法即聚合物喷发静电拉伸纺丝法，与传统方法有较大区别。首先将聚合物溶液或熔体带上几千至上万伏高压静电，带电的聚合物液滴在电场力的效果下形成泰勒锥。当电场力足够大时，聚合物液滴战胜外表张力构成喷发细流。细流在喷发进程中溶剂蒸腾或固化，最终落在接受设备上。
通过静电纺丝技术制备纳米纤维材料是近十几年来世界材料科学技术领域的最重要的学术与技术之一。静电纺丝以其制造装置简单、纺丝成本低廉、可纺物质种类繁多、工艺可控等优点，已成为有效制备纳米纤维材料的主要途径之一，特别其在美妆领域也有很大的发展潜力。
常见胶原面膜形式，通常都以湿式方式制造，将非织造布面膜纸浸泡在具有美容成分的精华液中。但湿式面膜的保存较为不易，由于精华液的成分多为高营养物质，高水活度的湿润环境易促进细菌或霉菌滋生，其保存期限较短，须添加防腐剂加以保存，从而容易发生过敏、进而引发接触性皮肤炎的疑虑，造成使用者的损害。
发明内容
本发明所要解决的技术问题是提供一种水刺/静电纺丝纳米纤维面膜及制备方法。
本发明的一种水刺/静电纺丝纳米纤维面膜，其特征在于，所述面膜依次包括，面膜基布、含营养液的静电纺纤维；其中含营养液的静电纺纤维以含骨胶原蛋白肽粉、增稠剂、白附子提取物、透明质酸、羧甲基纤维素钠、芦荟提取液、甘油、丁二醇、水的原料，通过静电纺获得。
所述面膜还包括静电纺TPU材料。
所述面膜依次包括，面膜基布、静电纺TPU材料，含营养液的静电纺纤维，静电纺TPU材料。
所述面膜基布为壳聚糖水刺无纺布；所述增稠剂为聚氧化乙烯PEO。
所述原料按重量份数，包括骨胶原蛋白肽粉80-100份、增稠剂10-15份、白附子提取物5-10份、透明质酸5-10份、羧甲基纤维素钠10-13份、芦荟提取液2-5份、甘油10-14份、丁二醇5-8份、水80-100份。
本发明的一种水刺/静电纺丝纳米纤维面膜的制备方法，包括：
将骨胶原蛋白肽粉、增稠剂、白附子提取物、透明质酸、羧甲基纤维素钠、芦荟提取液、甘油、丁二醇、水混合，得到营养液纺丝液；然后静电纺并负载在面膜基布表面，得到水刺/静电纺丝纳米纤维面膜；
或面膜基布作为接收装置，然后依次进行TPU溶液静电纺，营养液纺丝液静电纺，再进行TPU溶液静电纺，并依次负载在面膜基布表面，即得水刺/静电纺丝纳米纤维面膜。
所述TPU溶液的质量百分浓度为20％。
所述面膜基布为壳聚糖水刺无纺布。
所述壳聚糖水刺无纺布具体工艺流程为：纤维原料→开松混和→梳理→交织铺网→牵伸
→预湿→正反水刺→卷绕。
所述壳聚糖水刺无纺布具体工艺参数为：
将纤维加湿，加湿比例约0.5％-1％；提高开松梳理区的相对湿度，达到70％-80％；工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°；在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减道夫的齿深达到2.5mm；工作辊与锡林速度之比增大为1:12。
所述静电纺工艺参数均为：静电纺丝施加电压为11.4KV，纺丝喷头为无针式蝶形，接收距离16cm-20cm，纺丝温度为20℃-25℃，环境相对湿度为30％-65％。
所述面膜具体使用方法为：将带有纳米纤维活性物质的一面贴于面部，采用纯净水装于喷壶进行喷洒，15分钟后取下。
有益效果
(1)本发明使骨胶原形成纳米纤维，使得胶原蛋白更容易被皮肤所吸收。以去离子水为溶剂，对皮肤无刺激，且减少环境中的污染问题。
(2)以壳聚糖纤维进行水刺，制成面膜基布，增加了对面部的抑菌效果。
(3)本发明中添加白附子中药植物萃取皮肤美白成分，其具有非常高的安全性以及具有较高的和易吸收的优势。且芦荟本身就是一种肉质草药。它具有许多不同的功能，例如防腐，消炎，美容和皮肤护理以及保湿作用。二者协同可以从细胞到表皮全方位修复，从而达到更好的修复效果。
(4)本发明采用TPU静电纺材料包裹在活性两侧，将活性物质缓释到皮肤上，使皮肤更好的吸收活性物质。
(5)本发明中纳米纤维具有极大的比表面积和优异的孔隙率，极大地提高了面膜中活性成分的负载量；且具有完美的贴敷性和生物相容性，使活性成分能与皮肤更加充分地接触，并迅速渗透进入皮肤；其次面膜呈固态，不添加液体成分，降低精华液制作中的环境污染问题，且不添加防腐剂，对皮肤无刺激等这些优点，故将胶原蛋白使用静电纺丝法形成纳米纤维面膜。
附图说明
图1为本发明骨胶原蛋白静电纺丝纳米纤维膜；
图2为本发明采用的静电纺丝装置；
图3为面膜结构图；其中1-TPU；2-活性物质；3-TPU；4-面膜基布。
具体实施方式
下面结合具体实施例，进一步阐述本发明。应理解，这些实施例仅用于说明本发明而不用于限制本发明的范围。此外应理解，在阅读了本发明讲授的内容之后，本领域技术人员可以对本发明作各种改动或修改，这些等价形式同样落于本申请所附权利要求书所限定的范围。
实验中采用的壳聚糖纤维为市售，型号为L233A的短纤维；骨胶原蛋白肽粉由央企控股凯泰生物活性肽公司提供；增稠剂PEO、丁二醇、甘油、羧甲基纤维素钠，由上海易势化工有限公司提供；白附子提取物、透明质酸、芦荟提取液，由上海嘉楚生物工程有限公司。
实施例1
(1)壳聚糖水刺无纺布具体流程为：纤维原料→开松混和→梳理→交织铺网→牵伸→预湿→正反水刺→卷绕。
壳聚糖纤维抓取前首先要经过喷雾加湿，让纤维充分吸湿，加湿比例约0.5％-1％；同时提高开松梳理区的相对湿度，需要达到70％-80％。
甲壳素纤维梳理成网前的开松与混合采用快速速针帘自由开松、适度梳针打手握持开松打击等工艺措施，确保纤维有效充分开松，减少纤维损伤，保持纤维弹性。
工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°。
在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减少纤维间滑移，实现了纤网的顺利转移。此外，道夫的齿深达到2.5mm，有利于锡林与道夫间的气流排泄，更有利于纤网的均匀度。
为增加因降低锡林速度所造成的梳理度降低，将工作辊与锡林速度之比由1:10增大为1:12，增强分梳能力。
(2)将骨胶原蛋白肽粉溶于去离子水溶剂中，加入PEO，占胶原质量分数的25％。得到质量分数为15％的纺丝液，在室温下搅拌12h，搅拌速度为500r/h。
所述步骤2中，静电纺丝的工艺参数为：电压为10KV，接受距离为16cm，纺丝环境温度为25℃，纺丝环境湿度为60％。
实施例2
(1)壳聚糖水刺无纺布具体流程为：纤维原料→开松混和→梳理→交织铺网→牵伸→预湿→正反水刺→卷绕。
壳聚糖纤维抓取前首先要经过喷雾加湿，让纤维充分吸湿，加湿比例约0.5％-1％；同时提高开松梳理区的相对湿度，需要达到70％-80％。
甲壳素纤维梳理成网前的开松与混合采用快速速针帘自由开松、适度梳针打手握持开松打击等工艺措施，确保纤维有效充分开松，减少纤维损伤，保持纤维弹性。
工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°。
在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减少纤维间滑移，实现了纤网的顺利转移。此外，道夫的齿深达到2.5mm，有利于锡林与道夫间的气流排泄，更有利于纤网的均匀度。
为增加因降低锡林速度所造成的梳理度降低，将工作辊与锡林速度之比由1:10增大为1:12，增强分梳能力。
(2)将骨胶原蛋白肽粉100g，PEO15g，白附子提取物15g，透明质酸钠10g，羧甲基纤维素钠占13g，甘油14g，丁二醇8g，去离子水100g混合，在室温下搅拌12h,搅拌速度为500r/h。
静电纺丝的工艺参数为：电压为10KV，接受距离为16cm，纺丝环境温度为25℃，纺丝环境湿度为60％，并负载在壳聚糖水刺无纺布表面，得到面膜。
实施例3
(1)壳聚糖水刺无纺布具体流程为：纤维原料→开松混和→梳理→交织铺网→牵伸→预湿→正反水刺→卷绕。
壳聚糖纤维抓取前首先要经过喷雾加湿，让纤维充分吸湿，加湿比例约0.5％-1％；同时提高开松梳理区的相对湿度，需要达到70％-80％。
甲壳素纤维梳理成网前的开松与混合采用快速速针帘自由开松、适度梳针打手握持开松打击等工艺措施，确保纤维有效充分开松，减少纤维损伤，保持纤维弹性。
工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°。
在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减少纤维间滑移，实现了纤网的顺利转移。此外，道夫的齿深达到2.5mm，有利于锡林与道夫间的气流排泄，更有利于纤网的均匀度。
为增加因降低锡林速度所造成的梳理度降低，将工作辊与锡林速度之比由1:10增大为1:12，增强分梳能力。
(2)将骨胶原蛋白肽粉100g，PEO15g，透明质酸钠10g，羧甲基纤维素钠13g，芦荟提取液15g，甘油14g，丁二醇8g，去离子水100g混合，在室温下搅拌12h，搅拌速度为500r/h。
静电纺丝的工艺参数为：电压为10KV，接受距离为16cm，纺丝环境温度为25℃，纺丝环境湿度为60％，并负载在壳聚糖水刺无纺布表面，得到面膜。
实施例4
(1)壳聚糖水刺无纺布具体流程为：纤维原料→开松混和→梳理→交织铺网→牵伸→预湿→正反水刺→卷绕。
壳聚糖纤维抓取前首先要经过喷雾加湿，让纤维充分吸湿，加湿比例约0.5％-1％；同时提高开松梳理区的相对湿度，需要达到70％-80％。
甲壳素纤维梳理成网前的开松与混合采用快速速针帘自由开松、适度梳针打手握持开松打击等工艺措施，确保纤维有效充分开松，减少纤维损伤，保持纤维弹性。
工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°。
在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减少纤维间滑移，实现了纤网的顺利转移。此外，道夫的齿深达到2.5mm，有利于锡林与道夫间的气流排泄，更有利于纤网的均匀度。
为增加因降低锡林速度所造成的梳理度降低，将工作辊与锡林速度之比由1:10增大为1:12，增强分梳能力。
(2)将骨胶原蛋白肽粉100g，PEO15g，白附子提取物10g，透明质酸钠10g，羧甲基纤维素钠13g，芦荟提取液5g，甘油14g，丁二醇8g，去离子水100g混合，在室温下搅拌12h,搅拌速度为500r/h。
静电纺丝的工艺参数为：电压为10KV，接受距离为16cm，纺丝环境温度为25℃，纺丝环境湿度为60％，并负载在壳聚糖水刺无纺布表面，得到面膜。
实施例5
(1)壳聚糖水刺无纺布具体流程为：维原料→开松混和→梳理→交织铺网→牵伸→预湿
→正反水刺→卷绕。
壳聚糖纤维抓取前首先要经过喷雾加湿，让纤维充分吸湿，加湿比例约0.5％-1％；同时提高开松梳理区的相对湿度，需要达到70％-80％。
甲壳素纤维梳理成网前的开松与混合采用快速速针帘自由开松、适度梳针打手握持开松打击等工艺措施，确保纤维有效充分开松，减少纤维损伤，保持纤维弹性。
工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°。
在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减少纤维间滑移，实现了纤网的顺利转移。此外，道夫的齿深达到2.5mm，有利于锡林与道夫间的气流排泄，更有利于纤网的均匀度。
为增加因降低锡林速度所造成的梳理度降低，将工作辊与锡林速度之比由1:10增大为1:12，增强分梳能力。
(2)将骨胶原蛋白肽粉100g，PEO15g，白附子提取物10g，透明质酸钠10g，羧甲基纤维素钠13g，芦荟提取液5g，甘油14g，丁二醇8g，去离子水100g混合，在室温下搅拌12h,搅拌速度为500r/h。，形成纺丝液。
(3)质量百分浓度为20％的TPU溶液，在室温下搅拌12h。
依次进行TPU纺丝液静电纺丝，并负载在壳聚糖水刺无纺布表面，在将步骤(2)的活性物质纺丝液进行静电纺丝，并负载在含TPU的壳聚糖无纺布面膜基布表面，最后再将TPU采用静电纺丝的方式纺在活性物质纺丝液的表面。(TPU静电纺到活性物质两侧)。
静电纺丝的工艺参数均为：电压为10KV，接受距离为16cm，纺丝环境温度为25℃，纺丝环境湿度为60％。
效果验证
受试人数100人，根据使用产品不同分为5组，每组20人，试用部位为面部，第一周每两天使用一次；受试者处于20℃、40％相对湿度环境下，皮肤水分含量(％)测试结果如下：
本发明中包括骨胶原蛋白、透明质酸钠、白附子、芦荟提取物、增稠剂PEO、去离子水。配方中添加了羧甲基纤维素钠、甘油，更有利于人体皮肤稳态维持，同时在活性物质的两侧仿制TPU,对面膜起到缓释的效果，增加皮肤吸收程度，通过静电纺丝的生产方式使以上活性物质以纳米级的细度与壳聚糖类水刺无纺布基材进行复合。相较于现有技术配方，产品有效性和安全性更高、保湿效果好、可提高人体吸收、增加表皮修复速度、促进伤口愈合。
Claims (10)
1.一种水刺/静电纺丝纳米纤维面膜，其特征在于，所述面膜依次包括，面膜基布、含营养液的静电纺纤维；其中含营养液的静电纺纤维以含骨胶原蛋白肽粉、增稠剂、白附子提取物、透明质酸、羧甲基纤维素钠、芦荟提取液、甘油、丁二醇、水的原料，通过静电纺获得。
2.根据权利要求1所述面膜，其特征在于，所述面膜还包括静电纺TPU材料。
3.根据权利要求2所述面膜，其特征在于，所述面膜依次包括，面膜基布、静电纺TPU材料，含营养液的静电纺纤维，静电纺TPU材料。
4.根据权利要求1所述面膜，其特征在于，所述面膜基布为壳聚糖水刺无纺布；所述增稠剂为聚氧化乙烯PEO。
5.根据权利要求1所述面膜，其特征在于，所述原料按重量份数，包括骨胶原蛋白肽粉80-100份、增稠剂10-15份、白附子提取物5-10份、透明质酸5-10份、羧甲基纤维素钠10-13份、芦荟提取液2-5份、甘油10-14份、丁二醇5-8份、水80-100份。
6.一种水刺/静电纺丝纳米纤维面膜的制备方法，包括：
将骨胶原蛋白肽粉、增稠剂、白附子提取物、透明质酸、羧甲基纤维素钠、芦荟提取液、甘油、丁二醇、水混合，得到营养液纺丝液；然后静电纺并负载在面膜基布表面，得到水刺/静电纺丝纳米纤维面膜；
或面膜基布作为接收装置，然后依次进行TPU溶液静电纺，营养液纺丝液静电纺，再进行TPU溶液静电纺，并依次负载在面膜基布表面，即得水刺/静电纺丝纳米纤维面膜。
7.根据权利要求6所述制备方法，其特征在于，所述TPU溶液的质量百分浓度为20％。
8.根据权利要求6所述制备方法，其特征在于，所述面膜基布为壳聚糖水刺无纺布。
9.根据权利要求8所述制备方法，其特征在于，所述壳聚糖水刺无纺布具体工艺参数为：将纤维加湿，加湿比例约0.5％-1％；提高开松梳理区的相对湿度，达到70％-80％；工作辊采用渐密的组合方式，同时锡林工作角由80°调整为78°；在道夫齿形方面采用转移能力高的鹰嘴齿形，同时采用横纹设计，将锡林速度降至650m/min以下，道夫速度控制在60m/min以下，减道夫的齿深达到2.5mm；工作辊与锡林速度之比增大为1:12。
10.根据权利要求6所述制备方法，其特征在于，所述静电纺工艺参数均为：静电纺丝施加电压为11.4KV，纺丝喷头为无针式蝶形，接收距离16cm-20cm，纺丝温度为20℃-25℃，环境相对湿度为30％-65％。
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| WO2001026610A1 (en) * | 1999-10-08 | 2001-04-19 | The University Of Akron | Electrospun skin masks and uses thereof |
| CN111000751A (zh) * | 2019-12-11 | 2020-04-14 | 无限极（中国）有限公司 | 一种固态面膜及其制备方法 |
| CN111607965A (zh) * | 2020-05-27 | 2020-09-01 | 成都新柯力化工科技有限公司 | 一种纳米纤维水刺无纺布面膜基材及制备方法 |
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