CN113646635A - 产生循环分析物概况的方法和实施该方法的装置 - Google Patents

产生循环分析物概况的方法和实施该方法的装置 Download PDF

Info

Publication number
CN113646635A
CN113646635A CN202080026366.XA CN202080026366A CN113646635A CN 113646635 A CN113646635 A CN 113646635A CN 202080026366 A CN202080026366 A CN 202080026366A CN 113646635 A CN113646635 A CN 113646635A
Authority
CN
China
Prior art keywords
analyte
analytes
binding
probes
magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080026366.XA
Other languages
English (en)
Chinese (zh)
Inventor
王善祥
庄之颖
余珩
迈克尔·J.·贝格斯
路易斯·卡波纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Cikeda Medical Technology Co ltd
Wang Shanxiang
Original Assignee
MagArray Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MagArray Inc filed Critical MagArray Inc
Publication of CN113646635A publication Critical patent/CN113646635A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/485—Epidermal growth factor [EGF] (urogastrone)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
CN202080026366.XA 2019-04-04 2020-03-06 产生循环分析物概况的方法和实施该方法的装置 Pending CN113646635A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962829245P 2019-04-04 2019-04-04
US62/829,245 2019-04-04
PCT/US2020/021430 WO2020205158A1 (en) 2019-04-04 2020-03-06 Methods of producing circulating analyte profiles and devices for practicing same

Publications (1)

Publication Number Publication Date
CN113646635A true CN113646635A (zh) 2021-11-12

Family

ID=72661614

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080026366.XA Pending CN113646635A (zh) 2019-04-04 2020-03-06 产生循环分析物概况的方法和实施该方法的装置

Country Status (5)

Country Link
US (1) US20200319188A1 (OSRAM)
EP (1) EP3948293A4 (OSRAM)
JP (1) JP2022528692A (OSRAM)
CN (1) CN113646635A (OSRAM)
WO (1) WO2020205158A1 (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115575636B (zh) * 2022-11-22 2023-04-04 杭州广科安德生物科技有限公司 一种用于肺癌检测的生物标志物及其系统

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013154998A1 (en) * 2012-04-09 2013-10-17 Duke University Serum biomarkers and pulmonary nodule size for the early detection of lung cancer
CN108474779A (zh) * 2016-03-08 2018-08-31 马格雷股份有限公司 用于肺癌的诊断和治疗的蛋白质和自体抗体生物标志物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2419733A4 (en) * 2009-04-13 2013-12-25 Univ Leland Stanford Junior METHOD AND DEVICES FOR DETECTING THE PRESENCE OF AN ANALYZES IN A SAMPLE
CN104603289A (zh) * 2012-06-15 2015-05-06 哈里·斯泰利 检测疾病或病状的方法
SG11201408383SA (en) * 2012-06-15 2015-01-29 Harry Stylli Methods of detecting diseases or conditions using circulating diseased cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013154998A1 (en) * 2012-04-09 2013-10-17 Duke University Serum biomarkers and pulmonary nodule size for the early detection of lung cancer
CN108474779A (zh) * 2016-03-08 2018-08-31 马格雷股份有限公司 用于肺癌的诊断和治疗的蛋白质和自体抗体生物标志物

Also Published As

Publication number Publication date
US20200319188A1 (en) 2020-10-08
WO2020205158A1 (en) 2020-10-08
EP3948293A1 (en) 2022-02-09
EP3948293A4 (en) 2022-12-28
JP2022528692A (ja) 2022-06-15

Similar Documents

Publication Publication Date Title
CN108474779B (zh) 用于肺癌的诊断和治疗的蛋白质和自体抗体生物标志物
CN103597344B (zh) 用于样品中分析物的高通量检测的系统和方法
JP6104868B2 (ja) 磁気センサに基づく結合反応速度の定量的な分析
US10267871B2 (en) Magnetic tunnel junction sensors and methods for using the same
EP2401625B1 (en) High magnetic moment particle detection
CN107923877B (zh) 用于提高磁传感器灵敏度的装置和方法
US20200319188A1 (en) Methods of producing circulating analyte profiles and devices for practicing same
Roychoudhury Magnetic-based sensing
HK1259696A1 (en) Protein and autoantibody biomarkers for the diagnosis and treatment of lung cancer
HK1259696B (en) Protein and autoantibody biomarkers for the diagnosis and treatment of lung cancer

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20230803

Address after: California, USA

Applicant after: Wang Shanxiang

Address before: California, USA

Applicant before: MAGARRAY, Inc.

Effective date of registration: 20230803

Address after: Room 101-2, 1st Floor, Building 4, No. 525 Yuanjiang Road, Minhang District, Shanghai

Applicant after: Shanghai Cikeda Medical Technology Co.,Ltd.

Address before: California, USA

Applicant before: Wang Shanxiang