CN113621142A - Specific-morphology nano starch with efficient urea adsorption function and preparation method and application thereof - Google Patents

Specific-morphology nano starch with efficient urea adsorption function and preparation method and application thereof Download PDF

Info

Publication number
CN113621142A
CN113621142A CN202110881735.XA CN202110881735A CN113621142A CN 113621142 A CN113621142 A CN 113621142A CN 202110881735 A CN202110881735 A CN 202110881735A CN 113621142 A CN113621142 A CN 113621142A
Authority
CN
China
Prior art keywords
starch
nano
preparation
dmso
adsorption function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110881735.XA
Other languages
Chinese (zh)
Other versions
CN113621142B (en
Inventor
刘培
潘欣
张黄琴
张晔钧
钱大玮
段金廒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing University of Chinese Medicine
Original Assignee
Nanjing University of Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing University of Chinese Medicine filed Critical Nanjing University of Chinese Medicine
Priority to CN202110881735.XA priority Critical patent/CN113621142B/en
Publication of CN113621142A publication Critical patent/CN113621142A/en
Application granted granted Critical
Publication of CN113621142B publication Critical patent/CN113621142B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
    • A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/24—Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28023—Fibres or filaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2303/00—Characterised by the use of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08J2303/02—Starch; Degradation products thereof, e.g. dextrin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a specific-morphology nano-starch with a function of efficiently adsorbing urea and a preparation method thereof. By changing the volume ratio of DMSO to water and the input amount of starch, nano starch grains with flower-shaped, thread-shaped, sheet-shaped and other shapes can be formed, the grain size distribution of the formed nano starch grains is between 95 and 180nm, urea can be effectively adsorbed, and the adsorption amount is between 27.31 and 135.60 mg/g. The nano starch prepared by the method has the advantages of small particle size, uniform appearance, high yield and good urea adsorption capacity, and can be used as a dialysate regenerant to be applied to a hemodialysis system or a peritoneal dialysis system.

Description

Specific-morphology nano starch with efficient urea adsorption function and preparation method and application thereof
Technical Field
The invention relates to specific-morphology nano starch, in particular to a preparation method of specific-morphology nano starch with a function of efficiently adsorbing urea, which is obtained from corn starch, potato starch and trichosanthes starch (the crystal configuration is A, B or C type respectively).
Background
The nano-Starch (SNPs) is a natural novel nano-material with low cost and easy biodegradation, and has wide application prospect in the biomedical field taking antibiotics or anticancer drugs as a targeted drug delivery system. The final properties of SNPs are greatly influenced by the synthesis method and conditions, and nano-starch with different shapes and sizes can be prepared by adjusting the reaction conditions.
At present, the preparation of the nano starch is mainly obtained by an ultrasonic-assisted acid method or an enzyme method, or by adding a DMSO solution and heating. The acid treatment time is long, and the enzyme treatment cost is high.
The invention adopts ultrasonic wave assistance to ensure that the organic solvent dimethyl sulfoxide (DMSO) with different water contents can quickly convert starch into nano starch with specific morphology in a mild environment. The preparation method has the advantages of short time consumption, high efficiency and controllable product appearance, can greatly shorten the preparation time of the nano starch, and further meets the industrial requirement of the nano starch. The obtained nano starch with various shapes has the function of efficiently adsorbing urea, and can be used as a dialysate regenerant to be applied to a hemodialysis system or a peritoneal dialysis system.
Disclosure of Invention
The purpose of the invention is as follows: the invention aims to provide a method for preparing nano starch which is suitable for starch with various crystal configurations, short in time consumption, high in efficiency, controllable in product form, recyclable in solvent and high in urea adsorption function.
The technical scheme is as follows: in order to realize the purpose, the invention adopts the technical scheme that:
a nano-starch with specific morphology and high urea adsorption function is prepared from starch with various crystal configurations through preparing nano-starch with flower, thread and sheet morphologies and particle size distribution of 95-180 nm.
A preparation method of nano starch with a specific morphology and a function of efficiently adsorbing urea comprises the following steps:
a. adding corn starch, potato starch or fructus Trichosanthis starch into DMSO-water solution;
b. b, stirring the suspension obtained in the step a, and then performing ultrasonic treatment;
c. b, adding pure water into the suspension obtained in the step b, stirring again, and performing ultrasonic treatment;
d. and c, centrifuging the suspension obtained in the step c, taking the precipitate, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain the nano starch.
A preparation method of nano starch with a specific morphology and a function of efficiently adsorbing urea comprises the following steps:
a. adding DMSO-water solution into starch;
b. b, stirring the suspension obtained in the step a for 10min, and carrying out 400W ultrasonic treatment for 1 h;
c. b, adding 30mL of pure water into the suspension obtained in the step b, stirring for 10min again, and performing 400W ultrasonic treatment for 1 h;
d. and c, centrifuging 30000g of the suspension obtained in the step c for 30min, taking the precipitate, performing ultrasonic dispersion again by using deionized water, repeating the ultrasonic dispersion for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain the nano starch.
As a preferred scheme, the preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea is characterized by comprising the following steps: the starch in the step a comprises A-type crystalline corn starch, B-type crystalline potato starch and C-type crystalline trichosanthes starch.
As a preferable scheme, the preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea uses the DMSO-water solution assisted by ultrasound for treatment.
As a preferable scheme, the preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea can obtain the nano starch with various morphologies and sizes by controlling different feed ratios and the ratio of DMSO to water.
Preferably, in the preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea, the input amount of the starch in the step a is 250-750 g/L, and the concentration in DMSO is 50-100%.
Preferably, in the preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea, the input amount of the starch in the step a is 250g/L, 500g/L and 750g/L, and the concentration in DMSO is 80%, 90% and 100%.
An application of nano starch with a specific shape and a function of efficiently adsorbing urea in a hemodialysis system or a peritoneal dialysis system as a dialysate regenerating agent.
Has the advantages that: compared with the prior art, the invention has the following advantages:
(1) the preparation method of the nano starch provided by the invention is high in efficiency, the solvent can be recycled, and the production of the nano starch with different shapes can be effectively improved.
(2) The nano starch provided by the invention has small particle size and uniform appearance, and the appearance of the product can be controlled according to the amount of the controlled reactant.
(3) The nano starch provided by the invention has a function of efficiently adsorbing urea, and can be used as a dialysate regenerant to be applied to a hemodialysis system or a peritoneal dialysis system.
Drawings
FIG. 1 is a schematic diagram of XRD of different starches and a schematic diagram of absorption of 7 kinds of SNPs, wherein A is three kinds of common starch, B is corn starch and processed corn SNPs, C is potato starch and processed potato SNPs, and D is trichosanthes starch and processed trichosanthes SNPs; e is an adsorption kinetic curve of 7 SNPs, and F is an adsorption isotherm of 7 SNPs.
FIG. 2 is scanning electron microscope atlas of corn nanometer starch in different conditions.
FIG. 3 is scanning electron microscope atlas of potato nanometer starch of different conditions.
FIG. 4 is a scanning electron microscope atlas of Trichosanthes kirilowii Maxim nanometer starch under different conditions.
Detailed description of the preferred embodiments
The invention will be better understood from the following examples. However, one skilled in the art will readily appreciate that the specific manufacturing processes and functional evaluations described in the examples are merely illustrative of the present invention and should not, nor should they be construed as limiting the invention as detailed in the claims.
Example 1
The preparation method of the corn flake SNPs comprises the following steps:
taking 0.5g of corn starch, adding 20mL of 100% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from a product obtained by dialysis, and performing freeze drying to obtain corn flake SNPs (AD1), wherein SEM is shown in figure 2, XRD is shown in figure 1B, and the average particle size is shown in table 1.
Example 2
The preparation method of the corn flake SNPs comprises the following steps:
taking 1g of corn starch, adding 20mL of 90% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from a product obtained by dialysis, and performing freeze drying to obtain corn flake SNPs (AD5), wherein SEM is shown in figure 2, XRD is shown in figure 1B, and the average particle size is shown in table 1.
Example 3
A preparation method of potato flake SNPs comprises the following steps:
taking 0.5g of potato starch, adding 20mL of 100% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain potato flake SNPs (AD16), wherein SEM is shown in figure 3, XRD is shown in figure 1C, and the average particle size is shown in table 1.
Example 4
A preparation method of potato filamentous SNPs comprises the following steps:
taking 1.5g of potato starch, adding 20mL of 90% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain potato flake SNPs (AD21), wherein SEM is shown in figure 3, XRD is shown in figure 1C, and the average particle size is shown in table 1.
Example 5
A preparation method of trichosanthes kirilowii maxim flaky SNPs comprises the following steps:
taking 0.5g of trichosanthes starch, adding 20mL of 100% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from a product obtained by dialysis, and performing freeze drying to obtain trichosanthes slice SNPs (AD34), wherein SEM is shown in figure 4, XRD is shown in figure 1D, and the average particle size is shown in table 1.
Example 6
A preparation method of trichosanthes kirilowii flake SNPs comprises the following steps:
taking 1.5g of trichosanthes starch, adding 20mL of 90% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from a product obtained by dialysis, and performing freeze drying to obtain trichosanthes flaky SNPs (AD36), wherein SEM is shown in figure 4, XRD is shown in figure 1D, and the average particle size is shown in table 1.
Example 7
A preparation method of Trichosanthes kirilowii filiform SNPs comprises the following steps:
taking 1.5g of trichosanthes starch, adding 20mL of 80% DMSO, stirring for 10min, performing ultrasonic treatment for 1h, adding 30mL of pure water, stirring for 10min, continuing ultrasonic treatment for 1h, finally centrifuging 30000g for 30min, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from a product obtained by dialysis, and performing freeze drying to obtain trichosanthes filamentous SNPs (AD38), wherein SEM is shown in figure 4, XRD is shown in figure 1D, and the average particle size is shown in table 1.
Wherein AD2, AD3 and AD4 of Table 1 are prepared by the same process as in example 1; AD6, AD7, AD8 and AD9 were prepared by the same procedures as in example 2; AD17, AD18, AD19 and AD20 were prepared by the same procedures as in example 3; AD21, TABLE 1 sample preparation conditions for different SNPs
Figure BDA0003192612830000051
Figure BDA0003192612830000061
Example 8 Urea adsorption experiment
7 SNPs prepared in examples 1 to 7 and having different forms were measured as adsorption models, and their relative adsorption amounts in PBS were measured, and the parameters of adsorption curve fitting are shown in Table 2. Adsorption Capacity of the model for Urea (c)00.4mg/mL) showed that five SNPs (AD5, AD16, AD21, AD34, AD36) showed almost the same adsorption kinetics when urea was removed from PBS within 900 minutes, except for the sheet-like SNPs (AD1 and AD34) (fig. 1). The adsorption equilibrium time of the plate-like SNP was 120 minutes, and the adsorption equilibrium time of the other SNPs was 180 minutes.
When the adsorbate was gradually increased to 1.00mg/L, the adsorption amount of urea was different for the seven SNPs. The adsorption capacity of the corn starch nanoparticles AD1 and AD5 to urea is 52.67mg/g and 36.18 mg/g. The urea adsorption capacity of the potato starch nanoparticles AD16 and AD21 is up to 28.05mg/g and 27.31 mg/g. The urea content of the trichosanthes starch nanoparticles AD34, AD36 and AD38 is up to 135.60mg/g, 105.51mg/g and 62.19 mg/g.
TABLE 27 fitting curves for adsorption of Nano-starch
Figure BDA0003192612830000062
The invention develops a preparation method of novel nano starch, which can prepare the nano starch efficiently and rapidly; meanwhile, the prepared nano starch has an effective adsorption effect on urea, can provide raw materials for the development of a follow-up dialysate regenerating agent, is applied to a hemodialysis system or a peritoneal dialysis system, and has an important practical application value.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (9)

1. The specific-morphology nano starch with the efficient urea adsorption function is characterized in that the nano starch with flower-shaped, thread-shaped and sheet-shaped morphologies and particle sizes distributed between 95 nm and 180nm is obtained from starch with various crystal configurations.
2. The preparation method of the nano starch with the specific morphology and the function of efficiently adsorbing urea as claimed in claim 1, characterized by comprising the following steps:
a. adding corn starch, potato starch or fructus Trichosanthis starch into DMSO-water solution;
b. b, stirring the suspension obtained in the step a, and then performing ultrasonic treatment;
c. b, adding pure water into the suspension obtained in the step b, stirring again, and performing ultrasonic treatment;
d. and c, centrifuging the suspension obtained in the step c, taking the precipitate, performing ultrasonic dispersion again by using deionized water, repeating for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain the nano starch.
3. The preparation method of the nano-starch with the specific morphology and the high-efficiency urea adsorption function according to claim 2, characterized by comprising the following steps:
a. adding DMSO-water solution into starch;
b. b, stirring the suspension obtained in the step a for 10min, and carrying out 400W ultrasonic treatment for 1 h;
c. b, adding 30mL of pure water into the suspension obtained in the step b, stirring for 10min again, and performing 400W ultrasonic treatment for 1 h;
d. and c, centrifuging 30000g of the suspension obtained in the step c for 30min, taking the precipitate, performing ultrasonic dispersion again by using deionized water, repeating the ultrasonic dispersion for 3 times, removing impurities from the product obtained by dialysis, and performing freeze drying to obtain the nano starch.
4. The method for preparing nano starch with specific morphology and high urea adsorption function according to claim 2 or 3, characterized in that: the starch in the step a comprises A-type crystalline corn starch, B-type crystalline potato starch and C-type crystalline trichosanthes starch.
5. The method for preparing nano starch with specific morphology and high urea adsorption function according to claim 2 or 3, characterized in that: treatment with ultrasound-assisted DMSO-water solution was used.
6. The method for preparing nano starch with specific morphology and high urea adsorption function according to claim 2 or 3, characterized in that: by controlling different feed ratios and the ratio of DMSO to water, nano starch with various shapes and sizes can be obtained.
7. The method for preparing nano starch with specific morphology and high urea adsorption function according to claim 2 or 3, characterized in that: in the preparation method, the input amount of the starch in the step a is 250-750 g/L, and the concentration in DMSO is 50-100%.
8. The method for preparing nano starch with specific morphology and high urea adsorption function according to claim 2 or 3, characterized in that: in the preparation method, the input amount of the starch in the step a is 250g/L, 500g/L and 750g/L, and the concentration of DMSO is 80%, 90% and 100%.
9. The application of the nano-starch with specific morphology and high urea adsorption efficiency in the hemodialysis system or the peritoneal dialysis system as a dialysate regenerating agent in claim 1.
CN202110881735.XA 2021-08-02 2021-08-02 Nano starch with specific morphology and high-efficiency urea adsorption function, and preparation method and application thereof Active CN113621142B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110881735.XA CN113621142B (en) 2021-08-02 2021-08-02 Nano starch with specific morphology and high-efficiency urea adsorption function, and preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110881735.XA CN113621142B (en) 2021-08-02 2021-08-02 Nano starch with specific morphology and high-efficiency urea adsorption function, and preparation method and application thereof

Publications (2)

Publication Number Publication Date
CN113621142A true CN113621142A (en) 2021-11-09
CN113621142B CN113621142B (en) 2024-02-23

Family

ID=78382295

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110881735.XA Active CN113621142B (en) 2021-08-02 2021-08-02 Nano starch with specific morphology and high-efficiency urea adsorption function, and preparation method and application thereof

Country Status (1)

Country Link
CN (1) CN113621142B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114887495A (en) * 2022-04-27 2022-08-12 南京中医药大学 Preparation method and application of modified dialysis membrane with alkylated composite molybdenum disulfide as modifier and trichosanthes kirilowii pulp starch as coating thickener

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105199116A (en) * 2015-10-22 2015-12-30 吉林大学 Starch nanoparticle sedimentation preparation method through treatment of starch water solution by adopting ultrasonic wave
CN105916532A (en) * 2013-10-21 2016-08-31 Ic创新有限公司 Redox controlled electrosorption and decomposition device for the purification of blood and other fluids
CN109293953A (en) * 2018-09-17 2019-02-01 中南林业科技大学 A kind of preparation method of alcohol precipitation nano-starch particle
CN109293954A (en) * 2018-09-17 2019-02-01 中南林业科技大学 A kind of method that biological enzyme combination alkali Refrigeration Technique prepares nano-starch particle

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105916532A (en) * 2013-10-21 2016-08-31 Ic创新有限公司 Redox controlled electrosorption and decomposition device for the purification of blood and other fluids
CN105199116A (en) * 2015-10-22 2015-12-30 吉林大学 Starch nanoparticle sedimentation preparation method through treatment of starch water solution by adopting ultrasonic wave
CN109293953A (en) * 2018-09-17 2019-02-01 中南林业科技大学 A kind of preparation method of alcohol precipitation nano-starch particle
CN109293954A (en) * 2018-09-17 2019-02-01 中南林业科技大学 A kind of method that biological enzyme combination alkali Refrigeration Technique prepares nano-starch particle

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114887495A (en) * 2022-04-27 2022-08-12 南京中医药大学 Preparation method and application of modified dialysis membrane with alkylated composite molybdenum disulfide as modifier and trichosanthes kirilowii pulp starch as coating thickener
CN114887495B (en) * 2022-04-27 2024-05-07 南京中医药大学 Preparation method and application of modified dialysis membrane with alkylated composite molybdenum disulfide as modifier and trichosanthes kirilowii Maxim pulp starch as coating thickener

Also Published As

Publication number Publication date
CN113621142B (en) 2024-02-23

Similar Documents

Publication Publication Date Title
Khawaja et al. Graphene oxide decorated with cellulose and copper nanoparticle as an efficient adsorbent for the removal of malachite green
García-González et al. Polysaccharide-based aerogels—Promising biodegradable carriers for drug delivery systems
Naeini et al. Synthesis, characterization and application of carboxylmethyl cellulose, guar gam, and graphene oxide as novel composite adsorbents for removal of malachite green from aqueous solution
Zhu et al. Preparation, characterization, adsorption kinetics and thermodynamics of novel magnetic chitosan enwrapping nanosized γ-Fe2O3 and multi-walled carbon nanotubes with enhanced adsorption properties for methyl orange
Sangeetha et al. Production of bionanomaterials from agricultural wastes
Zhang et al. Citrus pectin derived ultrasmall Fe3O4@ C nanoparticles as a high-performance adsorbent toward removal of methylene blue
WO2021248696A1 (en) Separation and purification method for n-acetylglucosamine
Pareek et al. Bioconversion to chitosan: A two stage process employing chitin deacetylase from Penicillium oxalicum SAEM-51
CN101811665B (en) Method for preparing metal nano-particle modified polysaccharide wrapped carbon nano tube
WO2018054212A1 (en) Graphene composite, preparation method therefor and use thereof, method for preparing nanocellulose and resultant nanocellulose, and high-performance graphene composite nanocellulose and preparation method therefor
CN113621142A (en) Specific-morphology nano starch with efficient urea adsorption function and preparation method and application thereof
CN110229359B (en) UiO-66(NH2) Chitosan composite antibacterial film and preparation method and application thereof
WO2021248697A1 (en) Glucosamine salt produced by means of enzymatic method, and purification method therefor
Tan et al. Rational design and synthesis of chitosan–quinoa polysaccharide composite aerogel and its adsorption properties for Congo red and methylene blue
Hao et al. Integration of CdS particles into sodium alginate aerogel with enhanced photocatalytic performance
CN106832129A (en) A kind of itaconic acid homopolymers are grafted the preparation method of nanometer carboxymethyl chitosan particle
CN101357956A (en) Purification method of polyvinyl alcohol resin
Pan et al. Synthesis of starch nanoparticles with controlled morphology and various adsorption rate for urea
Chen et al. Sonochemical synthesis of γ-CD-MOFs microcapsule for myricetin delivery: Study of adsorption mechanism, molecular simulation, solubility, antioxidation, biocompatibility, and in vitro digestion
Yang et al. Preparation of starch nanoparticles by jet cavitation and enzymatic hydrolysis and their application in starch films
Balakrishnan et al. Chitosan/metal organic frameworks for environmental, energy, and bio-medical applications: a review
Li et al. Ultrasound-assisted acid/enzymatic hydrolysis preparation of loquat kernel porous starch: a carrier with efficient palladium loading capacity
Luo et al. Short-chain glucan self-assembly for green synthesis of functional biomaterials: Mechanism, synthesis, and microstructural control
González-García et al. Ag Nanoflowers and Nanodendrites Synthesized by a Facile Method and Their Antibacterial Activity
CN109289774B (en) Graphene microsphere aerogel for endotoxin adsorption and preparation method and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant