CN113617478A - Rupixiao plaster extract production device and preparation process - Google Patents

Rupixiao plaster extract production device and preparation process Download PDF

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Publication number
CN113617478A
CN113617478A CN202110900910.5A CN202110900910A CN113617478A CN 113617478 A CN113617478 A CN 113617478A CN 202110900910 A CN202110900910 A CN 202110900910A CN 113617478 A CN113617478 A CN 113617478A
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China
Prior art keywords
connecting rod
material containing
containing groove
extract
crushing
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Granted
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CN202110900910.5A
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Chinese (zh)
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CN113617478B (en
Inventor
袁野
马兰飞
马良
刘雪
李海涛
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Anhui Jinma Pharmaceutical Co ltd
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Anhui Jinma Pharmaceutical Co ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C18/00Disintegrating by knives or other cutting or tearing members which chop material into fragments
    • B02C18/06Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives
    • B02C18/08Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers
    • B02C18/10Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers with drive arranged above container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0041Mammary glands, e.g. breasts, udder; Intramammary administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C18/00Disintegrating by knives or other cutting or tearing members which chop material into fragments
    • B02C18/06Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives
    • B02C18/16Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Crushing And Grinding (AREA)

Abstract

The invention discloses a mammary nodule eliminating plaster extract production device which comprises a base, support frames arranged at two ends of the base, a support plate connected to the support frames, a material containing groove arranged on the support plate in a sliding manner, a driving assembly connected to the material containing groove and a crushing assembly arranged above the material containing groove, wherein the support frames are arranged on the two ends of the base; the driving assembly is used for driving the material containing groove to move on the supporting plate, and the crushing assembly is used for cutting and crushing the materials in the material containing groove; the invention also discloses a preparation process of the extract of the breast nodule eliminating plaster, wherein the driving component comprises a first connecting rod, a second connecting rod, a motor and a cam, the first connecting rod and the second connecting rod are horizontally arranged and are respectively arranged on the supporting frames at the two ends of the base in a sliding way, the first connecting rod and the second connecting rod are respectively connected with the left end and the right end of the material containing groove, and the first connecting rod is provided with a limiting bulge. The invention is mainly used for the crushing step of Chinese herbal medicine materials, and is convenient for the subsequent alcohol extraction.

Description

Rupixiao plaster extract production device and preparation process
Technical Field
The invention relates to the technical field of medicine production equipment, in particular to a device for producing an extract of a breast nodule eliminating plaster, and further relates to a preparation process of the extract of the breast nodule eliminating plaster.
Background
For a long time, women in society have many diseases on breasts, such as nodules of breast, qi stagnation and blood stasis, with the symptoms of breast agglomeration, distending pain and tenderness; cystic hyperplasia of breast. The mammary lump eliminating plaster is one domestic Chinese medicine preparation comprising 15 kinds of Chinese medicinal materials, including notoginseng, antler, seaweed, red peony root, dandelion, etc. The preparation has the advantages of strict and reasonable formula and definite curative effect, has the effects of softening hardness to dissipate stagnation, clearing away heat and toxic materials, and promoting blood circulation to arrest pain after being combined, and is an effective prescription for treating nodules of breast, qi stagnation and blood stasis and cystic hyperplasia of breast.
When preparing the extract of the breast nodule eliminating plaster, the traditional Chinese medicine is required to be subjected to alcohol extraction for many times, then the solution subjected to alcohol extraction is concentrated, and finally the preparation of the extract of the breast nodule eliminating plaster can be completed through various steps; in order to better realize the preparation of the extract of the breast nodule eliminating plaster, a production device of the extract of the breast nodule eliminating plaster is needed at present.
Disclosure of Invention
The invention aims to provide a mammary nodule eliminating plaster extract production device which is mainly used for the crushing step of Chinese herbal medicines and is convenient for the subsequent alcohol extraction; in addition, the invention also discloses a preparation process of the extract of the breast nodule eliminating plaster.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a breast nodule eliminating plaster extract production device comprises a base, support frames arranged at two ends of the base, a support plate connected on the support frames, a material containing groove arranged on the support plate in a sliding manner, a driving assembly connected on the material containing groove and a crushing assembly arranged above the material containing groove;
the driving assembly is used for driving the material containing groove to move on the supporting plate, and the crushing assembly is used for cutting and crushing the materials in the material containing groove;
the driving assembly comprises a first connecting rod, a second connecting rod, a motor and a cam, the first connecting rod and the second connecting rod are horizontally arranged and are respectively arranged on the supporting frames at the two ends of the base in a sliding mode, the first connecting rod and the second connecting rod are respectively connected with the left end and the right end of the material containing groove, a limiting bulge is arranged on the first connecting rod, a spring is sleeved on the first connecting rod, one end of the spring is connected with the supporting frame at the left end of the base, and the right end of the spring is connected with the limiting bulge;
the cam is installed on the output shaft of motor, and the right-hand member of second connecting rod and cam contact.
In some embodiments of the invention, the lower end of the material containing groove is provided with a universal wheel, and the material containing groove is connected with the supporting plate in a sliding manner through the universal wheel.
In some embodiments of the present invention, the support frame is provided with a linear bearing or a sliding sleeve, and the first and second connecting rods are slidably connected to the support frame through the linear bearing or the sliding sleeve, respectively.
In some embodiments of the invention, the right end of the second connecting rod is provided with a guide wheel, and the guide wheel is in contact with the side surface of the cam.
In some embodiments of the invention, the cam is provided with a limiting groove on the side surface, and the guide wheel is matched with the limiting groove.
In some embodiments of the present invention, the pulverizing assembly includes a fixing frame, a pulverizing motor, a connecting disc, a rotating disc and a cutter, the fixing frame is connected with the supporting frame, the pulverizing motor is installed on the fixing frame, the connecting disc is connected with an output shaft of the pulverizing motor, the cutter is arranged on the rotating disc, and the rotating disc is installed on the connecting disc.
In some embodiments of the invention, there are two of the rotating discs.
In some embodiments of the invention, a discharge pipe is arranged on the side surface of the material containing groove, and a valve is arranged on the discharge pipe.
In some embodiments of the invention, the end of the tapping pipe is provided with a quick connector.
In some embodiments of the present invention, the bottom of the trough has a slope.
Further preferably, the driving assembly further comprises two annular slide rails and two slide blocks, the annular slide rails are arranged on the side faces of the material containing groove, the slide blocks are matched with the arc-shaped slide rails, the first connecting rod is connected with one slide block, and the second connecting rod is connected with the other slide block;
wherein, be located the fixed rack that is provided with in the base of backup pad below, be provided with the recess in the backup pad, flourishing silo lower extreme is provided with the connecting axle, and the connecting axle is connected with the gear, the gear and rack mutually support.
The grinding machine is further optimized, the supporting frames at two ends of the base are connected with mounting plates, the fixing frame is arranged on the mounting plates in a sliding mode, a plurality of first motors are arranged on the connecting disc, the number of the first motors is equal to that of the rotating discs, the output shafts of the first motors are connected with the rotating discs, the connecting disc is connected with the output shaft of the grinding motor through a rotating shaft, a conductive sliding ring is arranged on the rotating shaft, and the first motors are connected with a power supply through the conductive sliding ring;
wherein, the mount is connected with the montant, is provided with first guide pulley on the montant, first guide pulley and cam side contact.
Wherein, the fixed mount is provided with a guide rod, the mounting plate is provided with a guide hole, and the guide rod is matched with the guide hole.
Further optimize, be provided with linear bearing in the guide hole, the guide arm passes through linear bearing and guide hole and mutually supports.
Compared with the prior art, the invention has the following beneficial effects:
the material cutting and crushing device mainly comprises a base, a support frame, a material containing groove, a driving assembly and a crushing assembly, wherein in actual use, a material with crushing is placed in the material containing groove, the driving assembly drives the material containing groove to move on a support plate, and meanwhile, the material is cut and crushed through the arranged crushing assembly; in actual use, the cam is driven to rotate by the arranged motor, the second connecting rod can be driven to move when the cam rotates, so that the material containing groove is driven to move on the supporting plate, and meanwhile, the first connecting rod can be reset after moving through the arranged spring; when the motor drive cam rotated, can realize holding the reciprocating motion about the silo, like this, when smashing the material of subassembly in to holding the silo, it was smashed better, the going on of the follow-up alcohol extraction step of being convenient for.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic overall structure diagram of a first embodiment of the present invention.
Fig. 2 is a schematic overall structure diagram of a third embodiment of the present invention.
Fig. 3 is a schematic view showing a connection relationship between the material containing tank and the first and second connecting rods in fig. 2 according to the present invention.
Reference numerals:
1-base, 2-support frame, 3-support plate, 4-material containing groove, 5-driving assembly, 6-crushing assembly, 7-first connecting rod, 8-second connecting rod, 9-motor, 10-cam, 11-limit bulge, 12-spring, 13-universal wheel, 14-linear bearing, 15-guide wheel, 16-limit groove, 17-fixing frame, 18-crushing motor, 19-connecting disc, 20-rotating disc, 21-cutter, 22-discharging pipe, 23-valve, 24-quick connector, 25-inclined plane, 26-annular slide rail, 27-slide block, 28-rack, 29-groove, 30-connecting shaft, 31-mounting plate, 32-conductive slide ring, 33-a first motor, 34-a first guide wheel, 35-a vertical rod, 36-a guide rod and 37-a guide hole.
Detailed Description
In the following, only certain exemplary embodiments are briefly described. As those skilled in the art will recognize, the described embodiments may be modified in various different ways, all without departing from the spirit or scope of the embodiments of the invention. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.
In the description of the embodiments of the present invention, it should be understood that the terms "length", "vertical", "horizontal", "top", "bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only used for convenience in describing the embodiments of the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the embodiments of the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the embodiments of the present invention, unless otherwise explicitly specified or limited, the terms "mounted," "connected," "fixed," and the like are to be construed broadly, e.g., as being fixedly connected, detachably connected, or integrated; the connection can be mechanical connection, electrical connection or communication; either directly or indirectly through intervening media, either internally or in any other relationship. Specific meanings of the above terms in the embodiments of the present invention can be understood by those of ordinary skill in the art according to specific situations.
In embodiments of the invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise the first and second features being in direct contact, or the first and second features being in contact, not directly, but via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly above and obliquely above the second feature, or simply meaning that the first feature is at a lesser level than the second feature.
The following disclosure provides many different embodiments or examples for implementing different configurations of embodiments of the invention. To simplify the disclosure of embodiments of the invention, the components and arrangements of specific examples are described below. Of course, they are merely examples and are not intended to limit embodiments of the invention. Furthermore, embodiments of the present invention may repeat reference numerals and/or letters in the various examples, such repetition is for the purpose of simplicity and clarity and does not in itself dictate a relationship between the various embodiments and/or configurations discussed.
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
Example one
Referring to fig. 1, the embodiment discloses a breast nodule eliminating plaster extract production device, which comprises a base 1, support frames 2 arranged at two ends of the base 1, a support plate 3 connected to the support frames 2, a material containing groove 4 arranged on the support plate 3 in a sliding manner, a driving assembly 5 connected to the material containing groove 4 and a crushing assembly 6 arranged above the material containing groove 4;
the driving assembly 5 is used for driving the material containing groove 4 to move on the supporting plate 3, and the crushing assembly 6 is used for cutting and crushing the materials in the material containing groove 4;
the driving assembly 5 comprises a first connecting rod 7, a second connecting rod 8, a motor 9 and a cam 10, wherein the first connecting rod and the second connecting rod are horizontally arranged and are respectively arranged on the supporting frames 2 at the two ends of the base 1 in a sliding manner, the first connecting rod 7 and the second connecting rod 8 are respectively connected with the left end and the right end of the material containing groove 4, a limiting bulge 11 is arranged on the first connecting rod 7, a spring 12 is sleeved on the first connecting rod 7, one end of the spring 12 is connected with the supporting frame 2 at the left end of the base 1, and the right end of the spring is connected with the limiting bulge 11;
the cam 10 is installed on the output shaft of the motor 9, and the right end of the second connecting rod 8 is in contact with the cam 10.
In the embodiment, the material containing device mainly comprises a base 1, a support frame 2, a material containing groove 4, a driving assembly 5 and a crushing assembly 6, wherein in actual use, a material with crushing function is placed in the material containing groove 4, the driving assembly 5 drives the material containing groove 4 to move on a support plate 3, and meanwhile, the material is cut and crushed through the arranged crushing assembly 6; in actual use, the cam 10 is driven to rotate by the arranged motor 9, the second connecting rod 8 can be driven to move when the cam 10 rotates, so that the material containing groove 4 is driven, the material containing groove 4 can move on the supporting plate 3, and meanwhile, the purpose of resetting after the first connecting rod moves can be achieved through the arranged spring 12; when the motor 9 drives the cam 10 to rotate, the left and right reciprocating movement of the material containing groove 4 can be realized, so that when the material in the material containing groove 4 is crushed by the crushing assembly 6, the crushing is better, and the subsequent alcohol extraction step is convenient to perform.
Wherein, hold the silo 4 lower extreme and be provided with universal wheel 13, hold silo 4 through universal wheel 13 and backup pad 3 sliding connection. The universal wheels 13 can be used for supporting the material containing groove 4 well.
In this embodiment, the support frame 3 is provided with a linear bearing 14 or a sliding sleeve, and the first and second connecting rods are slidably connected with the support frame 2 through the linear bearing 14 or the sliding sleeve, respectively. Thus, when the cam 10 drives the second connecting rod 8 to move, the first and second connecting rods move more smoothly.
Further preferably, a guide wheel 15 is arranged at the right end of the second connecting rod 8, and the guide wheel 15 is in contact with the side face of the cam 10; the abrasion of the second connecting rod 8 and the cam 10 caused by the direct contact of the second connecting rod 8 and the side surface of the cam 10 can be avoided through the arranged guide wheel 15.
Further preferably, a limiting groove 16 is formed in the side face of the cam 10, and the guide wheel 15 is matched with the limiting groove 16; the limiting hole can limit the guide wheel 15, so that the guide wheel 15 is more convenient to contact with the cam 10.
The crushing assembly 6 comprises a fixing frame 17, a crushing motor 18, a connecting disc 19, a rotating disc 20 and a cutter 21, the fixing frame 17 is connected with the support frame 2, the crushing motor 18 is installed on the fixing frame 17, the connecting disc 19 is connected with an output shaft of the crushing motor 18, the cutter 21 is arranged on the rotating disc 20, and the rotating disc 20 is installed on the connecting disc 19.
In this way, the arranged crushing motor 18 drives the connecting disc 19 to rotate, so that the rotating disc 20 on the connecting disc 19 rotates, and the material is cut and crushed by the cutter 21 on the rotating disc 20; like this, cutter 21 rotates, hold silo 4 round trip movement about simultaneously can effectual improvement cutting crushing effect and shorten crushing time.
Wherein, the rotating disc 20 has two, further improves the effect of cutting and crushing.
In the embodiment, a discharge pipe 22 is arranged on the side surface of the material containing groove 4, and a valve 23 is arranged on the discharge pipe 22; after the material is cut and crushed at the later stage, the extracting solution is injected into the material containing groove 4, so that the material and the extracting solution form a mixed solution, and then the valve 23 is opened to discharge the material liquid.
Further optimized, the end part of the discharge pipe 22 is provided with a quick connector 24; the connector through setting up is convenient for realize carrying out the high-speed joint with the passage.
Further optimized, the bottom of the material containing groove 4 is provided with an inclined plane 25; therefore, the bottom of the material containing groove 4 can form a structure which is higher at one side and lower at the other side, so that the material liquid can be discharged completely, and the blanking efficiency is improved.
In addition, the embodiment also discloses a preparation process of the extract of the breast nodule removing plaster, which specifically comprises the following steps: fully crushing the medicinal materials, performing alcohol extraction at least twice, concentrating the alcohol extract at least twice, and concentrating to obtain the Rupixiao plaster extract.
In this example, two alcohol extractions and two concentrations were performed.
Weighing radix aucklandiae, Prunellae Spica, radix Paeoniae Rubra, Notoginseng radix, caulis Spatholobi, Carthami flos, cortex moutan, Sargassum, thallus laminariae, fructus forsythiae, radix scrophulariae, Trichosanthis radix, herba Taraxaci, radix Rhapontici, and cornu Cervi, adding into a holding tank, and pulverizing; after the crushing is finished, adding ethanol into a material containing groove, mixing the medicinal materials with 95% ethanol, pouring out the mixture, heating, extracting the mixture with ethanol for 4 to 5 hours, and filtering to obtain primary ethanol extract;
adding 95% of the residue into the residue, and performing alcohol extraction for 2-3 hours to obtain a secondary alcohol extract;
mixing the primary and secondary alcohol extract, and concentrating under reduced pressure to remove ethanol; carrying out primary concentration for 5-6 hours under the conditions that the steam pressure is 0.1-0.15 Mpa, the vacuum degree is-0.06-0.08 Mpa and the temperature is 75-80 ℃ to obtain primary concentrated solution;
filtering the first concentrated solution by a 150-mesh filter screen, and then carrying out second concentration for 2 hours under the conditions that the steam pressure is 0.1-0.15 Mpa, the vacuum degree is-0.06-0.08 Mpa and the temperature is 70-80 ℃ to obtain the extract product of the breast nodule eliminating plaster.
Example two
Referring to fig. 2 and 3, the present embodiment is further optimized based on the first embodiment, in the present embodiment, the driving assembly 5 further includes an annular slide rail 26 and two slide blocks 27, the annular slide rail 26 is disposed on the side surface of the material containing groove 4, the slide blocks 27 are matched with the arc-shaped slide rail, the first connecting rod 7 is connected with one of the slide blocks 27, and the second connecting rod 8 is connected with the other slide block 27;
a rack 28 is fixedly arranged on the base 1 below the supporting plate 3, a groove 29 is formed in the supporting plate 3, a connecting shaft 30 is arranged at the lower end of the material containing groove 4, the connecting shaft 30 is connected with a gear, and the gear is matched with the rack 28.
Wherein the connection shaft 30 passes through said groove 29.
Thus, the annular slide rail 26, the slide block 27, the rack 28 and the gear are arranged, so that the material containing groove 4 can realize the purpose of autorotation in the process of reciprocating left and right, when the grinding motor 18 drives the connecting disc 19 to rotate, the cutter 21 on the rotating disc 20 cuts materials, at the moment, the material containing groove 4 realizes the purpose of reciprocating left and right under the action of the driving assembly 5, and realizes the purpose of alternately rotating clockwise and anticlockwise under the action of the gear and the rack 28; meanwhile, the connecting disc 19 drives the cutter 21 under the action of the crushing motor 18; so, in the in-service use, not only can improve the effect and the efficiency of smashing the cutting, also can be very big simultaneously shorten the cutting and smash the time, improve crushing efficiency.
In practical use, the connecting disc 19 realizes the purpose of positive and negative rotation alternately under the action of the crushing motor 18; when the material containing groove 4 rotates forwards, the connecting disc 19 rotates backwards; when the material containing groove 4 rotates reversely, the connecting disc 19 rotates forwards, so that the crushing effect of the materials can be further improved.
EXAMPLE III
The embodiment is further optimized on the basis of the second embodiment, in the embodiment, the supporting frames at two ends of the base are connected with the mounting plate 31, the fixing frame 17 is arranged on the mounting plate 31 in a sliding manner, the connecting disc 19 is provided with a plurality of first motors 33, the number of the first motors 33 is the same as that of the rotating discs 20, the output shafts of the first motors 33 are connected with the rotating discs 20, the connecting disc 19 is connected with the output shaft of the crushing motor 18 through a rotating shaft, the rotating shaft is provided with a conductive slip ring 32, and the first motors 33 are connected with a power supply through the conductive slip ring 32;
the fixing frame 17 is connected with a vertical rod 35, a first guide wheel 34 is arranged on the vertical rod 35, and the first guide wheel 34 is in contact with the side face of the cam 10.
In practical use, the cam 10 drives the second connecting rod 8 and the vertical rod 35 to move up and down, the connecting disc 19 is provided with the first motor 33, the first motor 33 is connected with the rotating disc 20, the crushing motor 18 drives the connecting disc 19 to rotate, the first motor 33 drives the cutter 21 on the rotating disc 20 to rotate, and the cutter 21 rotates and moves up; therefore, the aim of crushing the materials in multiple dimensions can be fulfilled in actual use.
Wherein, the fixed mount 17 is provided with a guide rod 36, the mounting plate 31 is provided with a guide hole 37, and the guide rod 36 is matched with the guide hole 37; the guide rod 36 and the guide hole 37 are arranged to form a guide structure, so that the fixed frame 17 is more stable when moving.
Preferably, the guide hole 37 is provided with a linear bearing 14, and the guide rod 36 is matched with the guide hole 37 through the linear bearing 14.
While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, it should be noted that any modifications, equivalents and improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (10)

1. A breast nodule disappears emplastrum extract apparatus for producing which characterized in that: the crushing device comprises a base, support frames arranged at two ends of the base, a support plate connected to the support frames, a material containing groove arranged on the support plate in a sliding manner, a driving assembly connected to the material containing groove and a crushing assembly arranged above the material containing groove;
the driving assembly is used for driving the material containing groove to move on the supporting plate, and the crushing assembly is used for cutting and crushing the materials in the material containing groove;
the driving assembly comprises a first connecting rod, a second connecting rod, a motor and a cam, the first connecting rod and the second connecting rod are horizontally arranged and are respectively arranged on the supporting frames at the two ends of the base in a sliding mode, the first connecting rod and the second connecting rod are respectively connected with the left end and the right end of the material containing groove, a limiting bulge is arranged on the first connecting rod, a spring is sleeved on the first connecting rod, one end of the spring is connected with the supporting frame at the left end of the base, and the right end of the spring is connected with the limiting bulge;
the cam is installed on the output shaft of motor, and the right-hand member of second connecting rod and cam contact.
2. The apparatus for producing extract of rupixiao plaster according to claim 1, wherein: the lower end of the material containing groove is provided with a universal wheel, and the material containing groove is connected with the supporting plate in a sliding mode through the universal wheel.
3. The apparatus for producing extract of rupixiao plaster according to claim 1, wherein: the support frame is provided with a linear bearing or a sliding sleeve, and the first connecting rod and the second connecting rod are respectively connected with the support frame in a sliding manner through the linear bearing or the sliding sleeve.
4. The apparatus for producing extract of rupixiao plaster according to claim 1, wherein: the right end of the second connecting rod is provided with a guide wheel which is in contact with the side face of the cam.
5. The apparatus for producing extract of rupixiao plaster according to claim 4, wherein: the side surface of the cam is provided with a limiting groove, and the guide wheel is matched with the limiting groove.
6. The apparatus for producing extract of rupi xiao plaster according to any one of claims 1 to 4, wherein: the crushing assembly comprises a fixing frame, a crushing motor, a connecting disc, a rotating disc and a cutter, the fixing frame is connected with the supporting frame, the crushing motor is installed on the fixing frame, the connecting disc is connected with an output shaft of the crushing motor, the cutter is arranged on the rotating disc, and the rotating disc is installed on the connecting disc.
7. The apparatus for producing extract of rupixiao plaster according to claim 6, wherein: the rotating discs are two.
8. The apparatus for producing extract of rupixiao plaster according to claim 6, wherein: the side surface of the material containing groove is provided with a material discharging pipe, and the material discharging pipe is provided with a valve.
9. The apparatus for producing extract of rupixiao plaster according to claim 8, wherein: the end part of the discharge pipe is provided with a quick connector.
10. A preparation process of an extract of a breast nodule eliminating plaster is characterized by comprising the following steps: the method specifically comprises the following steps of,
fully crushing the medicinal materials, performing alcohol extraction twice at least, concentrating the alcohol extract twice at least, and concentrating to obtain Rupixiao plaster extract; wherein, the device for producing the extract of the breast nodule eliminating plaster in any one of claims 1 to 9 is adopted when the medicinal materials are crushed.
CN202110900910.5A 2021-08-06 2021-08-06 Device and process for producing paste extract for eliminating nodules of breast Active CN113617478B (en)

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CN106423436A (en) * 2016-12-16 2017-02-22 滁州胜全农业开发有限公司 Rapid chopping device for traditional Chinese medicinal materials for medical treatment
CN107486304A (en) * 2017-09-08 2017-12-19 朱玥 A kind of Chinese medicine efficient pulverizing screening plant
CN107683708A (en) * 2017-09-11 2018-02-13 遂昌县宏创技术开发有限公司 A kind of forage fly-cutting screening plant
CN108295147A (en) * 2018-03-08 2018-07-20 安徽金马药业有限公司 A kind of process of preparing of RUPIXIAO TIEGAO medicinal extract
CN108325640A (en) * 2018-01-25 2018-07-27 冯斌斌 A kind of new bio extraction element
CN208194557U (en) * 2018-04-05 2018-12-07 何志贤 A kind of efficient Chinese medicine shredding mechanism
JP6583800B1 (en) * 2018-05-07 2019-10-02 广州立奔杯業有限公司 Herbal medicine processing equipment
CN111468221A (en) * 2020-04-15 2020-07-31 新沂市瑞阳混凝土工程有限公司 Pre-crushing type environment-friendly concrete waste recycling device
CN211587530U (en) * 2020-01-06 2020-09-29 浙江越诗花卉科技有限公司 Plant waste treatment device is used in gardens

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106423436A (en) * 2016-12-16 2017-02-22 滁州胜全农业开发有限公司 Rapid chopping device for traditional Chinese medicinal materials for medical treatment
CN107486304A (en) * 2017-09-08 2017-12-19 朱玥 A kind of Chinese medicine efficient pulverizing screening plant
CN107683708A (en) * 2017-09-11 2018-02-13 遂昌县宏创技术开发有限公司 A kind of forage fly-cutting screening plant
CN108325640A (en) * 2018-01-25 2018-07-27 冯斌斌 A kind of new bio extraction element
CN108295147A (en) * 2018-03-08 2018-07-20 安徽金马药业有限公司 A kind of process of preparing of RUPIXIAO TIEGAO medicinal extract
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CN211587530U (en) * 2020-01-06 2020-09-29 浙江越诗花卉科技有限公司 Plant waste treatment device is used in gardens
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Address after: 236000 No.1 Jingsi Road, Yingdong Economic Development Zone, Fuyang City, Anhui Province

Patentee after: Anhui Jinma Pharmaceutical Co.,Ltd.

Address before: 236000 No. 1, Jingsi Road, Yingdong Economic Development Zone, Bengbu City, Anhui Province

Patentee before: Anhui Jinma Pharmaceutical Co.,Ltd.