CN113533327A - Remote pathological diagnosis implementation method combining electric control image acquisition and splicing - Google Patents

Remote pathological diagnosis implementation method combining electric control image acquisition and splicing Download PDF

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Publication number
CN113533327A
CN113533327A CN202110752380.4A CN202110752380A CN113533327A CN 113533327 A CN113533327 A CN 113533327A CN 202110752380 A CN202110752380 A CN 202110752380A CN 113533327 A CN113533327 A CN 113533327A
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image
moving
distance
same distance
tray
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冯浩
李硕
杨义
李彦生
李林起
冯潇然
陶冶
孙晗雅
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106General arrangement of respective parts
    • G01N2021/0112Apparatus in one mechanical, optical or electronic block

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
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  • Pathology (AREA)
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Abstract

The invention discloses a remote pathological diagnosis realization method combining electric control collected images and splicing, which can complete the splicing of pathological section images, and also discloses a remote pathological diagnosis device combining electric control collected images and splicing. This device can carry out pathological section's removal through servo motor driven mode, and then obtains the convenient concatenation of photo in suitable position, and very possess the practicality.

Description

Remote pathological diagnosis implementation method combining electric control image acquisition and splicing
Technical Field
The invention particularly relates to a remote pathological diagnosis implementation method combining electric control image acquisition and splicing.
Background
The prior art situation is as follows: the pathological section is a substance which is processed by various chemicals and an embedding method to fix and harden part of tissues or organs with pathological changes, is cut into slices on a slicer, is adhered on a glass sheet and dyed with various colors for being examined under a microscope to observe pathological changes and make pathological diagnosis and provide help for clinical diagnosis and treatment, the existing pathological section usually only observes a small part of a body during observation and needs a worker to move to observe so as to find a more proper observation position, the method is more troublesome, therefore, the method adopts the mode of collecting images at observation points and splicing the image information of most pathological sections by a system in the later period, and the problem that the images cannot be spliced into finished images due to overlarge moving distance is serious, therefore, the invention provides a remote pathological diagnosis device combining electric control image acquisition and splicing.
Disclosure of Invention
In order to solve the technical problems, the invention aims to provide a remote pathological diagnosis implementation method combining electric control image acquisition and splicing, which comprises the following steps:
(1) the method comprises the following steps that a remote pathological diagnosis device combining electric control image acquisition and splicing moves pathological sections needing image acquisition to a central position;
(2) taking a first image S1, cutting the image S1 into a square;
(3) moving the image S1 in the vertical direction of any one of the X axis and the Y axis by the distance of 0.9 times of the side length dimension by taking the image S1 as a standard, and shooting to obtain an image S2;
(4) moving the image S1 arbitrarily by a distance of 0.9 times the length dimension in a direction perpendicular to the direction of the last movement with the image S2 as a reference and capturing to obtain an image S3;
(5) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S3 as a reference, shooting to obtain an image S4, and then continuously moving the same distance to obtain S5;
(6) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S5 as a reference, shooting to obtain an image S6, and then continuously moving the same distance to obtain S7;
(7) moving the image S1 in the same moving direction in the step (3) by the distance of 0.9 times of the length of the side with the image S7 as a reference, shooting to obtain an image S8, then continuously moving the same distance to obtain S9, and then continuously moving the same distance to obtain S10;
(8) moving the image S1 in the same moving direction in the step (4) by the distance of 0.9 times of the length of the side with the image S10 as a reference, shooting to obtain an image S11, then continuously moving the same distance to obtain S12, and then continuously moving the same distance to obtain S13;
(9) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S13 as a reference, shooting to obtain an image S14, then continuously moving by the same distance to obtain an image S15, then continuously moving by the same distance to obtain an image S16, and then continuously moving to obtain an image S17;
(10) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S17 as a reference, shooting to obtain an image S18, then continuously moving by the same distance to obtain an image S19, then continuously moving by the same distance to obtain an image S20, and then continuously moving to obtain an image S21;
(11) moving the image S1 by the distance of 0.9 times of the length of the side in the same moving direction of the image S21 according to the image S1 bit, shooting to obtain an image S22, then continuously moving the image S1 by the same distance to obtain S23, then continuously moving the image S24 by the same distance to obtain an image S25;
(12) the above-described images S1 to S25 are spliced into a completed square image, and the excess portion is cut for observation.
Preferably, the total number of images is quadratic to the conventional singular number.
Preferably, the number of said images in total is 25, 49, 81 or 121.
Remote pathological diagnosis device that electric control gathered image and concatenation combined together, including observing the eyepiece, it sets up on the microscope body to observe the eyepiece, still be provided with vertical eyepiece of making a video recording on the microscope body, it gathers the camera to be provided with on the eyepiece of making a video recording, still be provided with the tray under the microscope body, the tray can remove, be provided with the platform of placing that can remove on the tray, it is provided with the lamp source to place platform department, the microscope body supports fixedly and sets up on the mesa through the support frame, the mesa supports through the bracing piece that circumference set up.
Preferably, the tray can move in a manner that a servo motor is arranged below the table board, an output shaft of the servo motor is connected with a screw rod, a screw rod seat is arranged on the screw rod, a fixing plate is fixed on the screw rod seat and connected with the tray through a connecting rod, and the tray is arranged on the guide rail.
Preferably, the placing table of the tray can be moved in a manner that the tray comprises a tray body, four fixing seats are circumferentially arranged on the upper surface of the tray body, a cylindrical guide rail is arranged between the transversely adjacent fixing seats, a moving seat is sleeved on the cylindrical guide rail, the moving seats are circumferentially arranged in four, the moving seat can move on the cylindrical guide rail, and the placing table is fixedly arranged on the moving seat.
Preferably, a penetrating screw rod is arranged in the cylindrical guide rail and driven by a servo driving motor arranged outside the fixed seat, the cylindrical guide rail is provided with two sections, a gap exists between the adjacent cylindrical guide rails, a driving screw rod seat is arranged at the gap and arranged on the penetrating screw rod, and the driving screw rod seat is fixedly connected with the fixed placing table.
Compared with the prior art, the invention has the following beneficial effects: the mode that current pathological section can usually be through the image concatenation when observing generates large-scale picture, is convenient for observe and contrast, and this kind of mode needs pathological section to remove then carries out a lot of through gathering the camera and take a picture and splice, consequently this device can carry out pathological section's removal through servo motor driven mode, and then obtains the convenient concatenation of photo in suitable position, and ten minutes possesses the practicality.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the tray structure of the present invention;
FIG. 3 is a diagram illustrating a moving track of a captured image according to the present invention.
Detailed Description
In the following, the technical solutions in the embodiments of the present invention will be clearly and completely described with reference to the drawings provided in the embodiments of the present invention, and it is obvious that the described embodiments are only preferred embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the preferred embodiments of the invention without making any creative effort, shall fall within the protection scope of the invention. The present invention is described in further detail below.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings. The foregoing definitions are provided merely to facilitate description and to simplify description and are not intended to indicate or imply that the structures referred to must have a particular orientation, be constructed and operated in a particular orientation and are not to be construed as limiting the invention.
As shown in fig. 1-2, the present invention provides a method for implementing remote pathological diagnosis by combining electric control image acquisition and stitching, comprising the following steps:
(1) the method comprises the following steps that a remote pathological diagnosis device combining electric control image acquisition and splicing moves pathological sections needing image acquisition to a central position;
(2) taking a first image S1, cutting the image S1 into a square;
(3) moving the image S1 in the vertical direction of any one of the X axis and the Y axis by the distance of 0.9 times of the side length dimension by taking the image S1 as a standard, and shooting to obtain an image S2;
(4) moving the image S1 arbitrarily by a distance of 0.9 times the length dimension in a direction perpendicular to the direction of the last movement with the image S2 as a reference and capturing to obtain an image S3;
(5) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S3 as a reference, shooting to obtain an image S4, and then continuously moving the same distance to obtain S5;
(6) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S5 as a reference, shooting to obtain an image S6, and then continuously moving the same distance to obtain S7;
(7) moving the image S1 in the same moving direction in the step (3) by the distance of 0.9 times of the length of the side with the image S7 as a reference, shooting to obtain an image S8, then continuously moving the same distance to obtain S9, and then continuously moving the same distance to obtain S10;
(8) moving the image S1 in the same moving direction in the step (4) by the distance of 0.9 times of the length of the side with the image S10 as a reference, shooting to obtain an image S11, then continuously moving the same distance to obtain S12, and then continuously moving the same distance to obtain S13;
(9) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S13 as a reference, shooting to obtain an image S14, then continuously moving by the same distance to obtain an image S15, then continuously moving by the same distance to obtain an image S16, and then continuously moving to obtain an image S17;
(10) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S17 as a reference, shooting to obtain an image S18, then continuously moving by the same distance to obtain an image S19, then continuously moving by the same distance to obtain an image S20, and then continuously moving to obtain an image S21;
(11) moving the image S1 by the distance of 0.9 times of the length of the side in the same moving direction of the image S21 according to the image S1 bit, shooting to obtain an image S22, then continuously moving the image S1 by the same distance to obtain S23, then continuously moving the image S24 by the same distance to obtain an image S25;
(12) the above-described images S1 to S25 are spliced into a completed square image, and the excess portion is cut for observation.
The overall number of images is the square of the conventional singular number.
The overall number of images is 25, 49, 81 or 121.
The above steps can be extended with the same rule, and as the case may be, selecting a square of singular number can ensure that the final image is a square, with no limitation on the direction, and the final result is a complete square image.
The utility model provides a remote pathological diagnosis device that image and concatenation combined together are gathered in electric control, is including observing eyepiece 1, observe eyepiece 1 and set up on microscope body 3, still be provided with vertical eyepiece of making a video recording on microscope body 3, be provided with on the eyepiece of making a video recording and gather camera 2 the microscope body 3 still is provided with tray 4 down, tray 4 can remove, be provided with the platform 45 of placing that can remove on the tray 4, place platform 45 department and be provided with lamp source 46, microscope body 3 supports fixedly and sets up on mesa 10 through support frame 12, mesa 10 supports through the bracing piece 11 that circumference set up.
The tray 4 can move in a mode that a servo motor is arranged below the table board 10, an output shaft of the servo motor is connected with a screw rod 9, a screw rod seat 8 is arranged on the screw rod 9, a fixing plate 7 is fixed on the screw rod seat 8, the fixing plate 7 is connected with the tray 4 through a connecting rod 6, and the tray 4 is arranged on a guide rail 5.
The placing table 45 of the tray 4 can move in a manner that the tray 4 comprises a tray body 41, four fixing seats 42 are circumferentially arranged on the upper surface of the tray body 41, a cylindrical guide rail 43 is arranged between the transversely adjacent fixing seats 42, a moving seat 44 is sleeved on the cylindrical guide rail 43, four moving seats 44 are circumferentially arranged, the moving seat 44 can move on the cylindrical guide rail 43, and the placing table 45 is fixedly arranged on the moving seat 44.
The novel cylindrical guide rail structure is characterized in that a penetrating screw rod 48 is arranged in the cylindrical guide rail 43, the penetrating screw rod 48 is driven by a servo driving motor 49 arranged outside the fixing seat 42, the cylindrical guide rail 43 is provided with two sections, a gap exists between the adjacent cylindrical guide rails 43, a driving screw rod seat 47 is arranged at the gap, the driving screw rod seat 47 is arranged on the penetrating screw rod 48, and the driving screw rod seat 47 is fixedly connected with the fixed placing platform 45.
During the device use, at first place the pathological section that needs to gather on placing platform 45, later shoot by gathering camera 2, and move on running through lead screw 48 through drive lead screw seat 47, can change the position of placing platform 45, it can obtain a plurality of pictures to shoot after changing certain position, and tray 4 can move on guide rail 5, and then obtain the two-way vertical position regulation of XY axle, can obtain a plurality of pictures then splice, and then obtain the pathological section image of a comparison and play, make things convenient for the staff to look over and judge, it is very effective.
Finally, the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all of them should be covered in the claims of the present invention.

Claims (7)

1. The method for realizing remote pathological diagnosis by combining electric control image acquisition and splicing is characterized by comprising the following steps of:
(1) the method comprises the following steps that a remote pathological diagnosis device combining electric control image acquisition and splicing moves pathological sections needing image acquisition to a central position;
(2) taking a first image S1, cutting the image S1 into a square;
(3) moving the image S1 in the vertical direction of any one of the X axis and the Y axis by the distance of 0.9 times of the side length dimension by taking the image S1 as a standard, and shooting to obtain an image S2;
(4) moving the image S1 arbitrarily by a distance of 0.9 times the length dimension in a direction perpendicular to the direction of the last movement with the image S2 as a reference and capturing to obtain an image S3;
(5) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S3 as a reference, shooting to obtain an image S4, and then continuously moving the same distance to obtain S5;
(6) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S5 as a reference, shooting to obtain an image S6, and then continuously moving the same distance to obtain S7;
(7) moving the image S1 in the same moving direction in the step (3) by the distance of 0.9 times of the length of the side with the image S7 as a reference, shooting to obtain an image S8, then continuously moving the same distance to obtain S9, and then continuously moving the same distance to obtain S10;
(8) moving the image S1 in the same moving direction in the step (4) by the distance of 0.9 times of the length of the side with the image S10 as a reference, shooting to obtain an image S11, then continuously moving the same distance to obtain S12, and then continuously moving the same distance to obtain S13;
(9) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (3) by taking the image S13 as a reference, shooting to obtain an image S14, then continuously moving by the same distance to obtain an image S15, then continuously moving by the same distance to obtain an image S16, and then continuously moving to obtain an image S17;
(10) moving the image S1 by a distance of 0.9 times the length of the side in the moving direction opposite to the step (4) by taking the image S17 as a reference, shooting to obtain an image S18, then continuously moving by the same distance to obtain an image S19, then continuously moving by the same distance to obtain an image S20, and then continuously moving to obtain an image S21;
(11) moving the image S1 by the distance of 0.9 times of the length of the side in the same moving direction of the image S21 according to the image S1 bit, shooting to obtain an image S22, then continuously moving the image S1 by the same distance to obtain S23, then continuously moving the image S24 by the same distance to obtain an image S25;
(12) the above-described images S1 to S25 are spliced into a completed square image, the excess portion is cut,
for easy observation.
2. The method for realizing remote pathological diagnosis by combining electrically-controlled acquisition of images and splicing according to claim 1, wherein the whole number of the images is quadratic to the conventional singular number.
3. The method for realizing remote pathological diagnosis by combining electrically-controlled acquisition of images and stitching according to claim 2, wherein the number of the images is 25, 49, 81 or 121.
4. Remote pathological diagnosis device that electric control gathered image and concatenation combined together, its characterized in that, including observing the eyepiece, observe the eyepiece setting on the microscope body, still be provided with vertical eyepiece of making a video recording on the microscope body, be provided with the collection camera on the eyepiece of making a video recording, still be provided with the tray under the microscope body, the tray can remove, be provided with the platform of placing that can remove on the tray, it is provided with the lamp source to place platform department, the microscope body passes through the support frame and supports fixedly and set up on the mesa, the mesa passes through the bracing piece support that circumference set up.
5. The device for remote pathological diagnosis combining image collection and splicing according to claim 4, wherein the tray is movable in such a way that a servo motor is disposed under the table top, an output shaft of the servo motor is connected with a lead screw, a lead screw seat is disposed on the lead screw, a fixing plate is fixed on the lead screw seat, the fixing plate is connected with the tray through a connecting rod, and the tray is disposed on a guide rail.
6. The device for remote pathological diagnosis combining electrically controlled image collection and splicing according to claim 4, wherein the tray comprises a tray body, four fixing bases are circumferentially arranged on the upper surface of the tray body, a cylindrical guide rail is arranged between the transversely adjacent fixing bases, a moving base is sleeved on the cylindrical guide rail, four moving bases are circumferentially arranged, the moving base can move on the cylindrical guide rail, and the placing table is fixed on the moving base.
7. The device for remote pathological diagnosis combining electrically controlled image collection and splicing according to claim 6, wherein a penetrating screw rod is arranged in the cylindrical guide rail, the penetrating screw rod is driven by a servo driving motor arranged outside the fixing base, the cylindrical guide rail is provided with two sections, a gap is formed between the adjacent cylindrical guide rails, a driving screw rod seat is arranged at the gap, the driving screw rod seat is arranged on the penetrating screw rod, and the driving screw rod seat is fixedly connected with the fixing placing table.
CN202110752380.4A 2021-07-02 2021-07-02 Remote pathological diagnosis implementation method combining electric control image acquisition and splicing Withdrawn CN113533327A (en)

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CN202110752380.4A CN113533327A (en) 2021-07-02 2021-07-02 Remote pathological diagnosis implementation method combining electric control image acquisition and splicing

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Application Number Priority Date Filing Date Title
CN202110752380.4A CN113533327A (en) 2021-07-02 2021-07-02 Remote pathological diagnosis implementation method combining electric control image acquisition and splicing

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Application publication date: 20211022