CN113520476A - Drug detects uses saliva collector and complex mouthwash thereof - Google Patents
Drug detects uses saliva collector and complex mouthwash thereof Download PDFInfo
- Publication number
- CN113520476A CN113520476A CN202110862006.XA CN202110862006A CN113520476A CN 113520476 A CN113520476 A CN 113520476A CN 202110862006 A CN202110862006 A CN 202110862006A CN 113520476 A CN113520476 A CN 113520476A
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- China
- Prior art keywords
- saliva
- parts
- saliva collecting
- mouthwash
- water bag
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
The invention discloses a saliva collector for drug detection and a matched mouthwash thereof, which comprises a saliva collecting mechanism, the saliva collecting mechanism comprises a saliva collecting port and a saliva collecting pipe connected to the saliva collecting port, the saliva collecting tube is characterized in that a detachable mouth wash bag and a detachable clear water bag are hung on the side wall of the saliva collecting tube, sealing covers capable of being opened and closed repeatedly are arranged at openings of the mouth wash bag and the clear water bag, and mouth wash water containing 80 parts of water, 10 parts of citric acid, 5 parts of alcohol, 2 parts of xylitol, 1.5 parts of glycerol, 1 part of sorbitol and 0.5 part of mint extract is pre-filled in the mouth wash bag.
Description
Technical Field
The invention relates to the field of drug detection, in particular to a saliva collector for drug detection and a mouthwash matched with the saliva collector.
Background
POCT is the abbreviation of Point of Care Testing, and the Chinese name is 'instant detection', and has the characteristics of rapidness, convenience, field analysis and the like. From the perspective of global market, POCT products are widely pursued due to the instant and convenient characteristics, and the global market is over one billion; the POCT market in China starts late, but in recent years, the industry acceleration is always kept at 10% -20% and is far higher than that of 6% -7% of the world, and the market scale reaches 14.3 hundred million dollars in 2018. According to TriMark prediction, the POCT market scale in China can reach 26.0 hundred million dollars in 2021 years, and can reach about 225 million dollars in 2025 years.
China POCT starts late, the market scale is small, infection detection products occupy the first place (27.5%) in the POCT field in China according to statistics of an industrial information network in 2017, the market scale is about 21.4 hundred million yuan, blood gas detection and cardiovascular detection are carried out, the market scale proportion is equivalent, and the exotic proportion of the blood gas market is up to 90%. According to the TriMark prediction, the market scale of POCT industry in China in 2018 is $ 14.3 billion, the annual composite acceleration rate of 22% is maintained in the last years, and the market scale is predicted to reach $ 26 billion in 2021.
According to WorldDrugReport2019 issued by the world health organization, the severity and complexity of the world drug situation are increasing, the number of drug use cases in 2019 is 30% higher than that in 2009, and all governments adopt drug contraband measures to control the spread of drugs. Therefore, from the global perspective, the instant detection of drugs will become a significant trend in the background of drug inhibition in the world, and the drug POCT product market has a wide future development prospect.
The main drug instant detection products in the current market mainly aim at urine samples, but have the defects that the drug addict can only know the drug addict in nearly a few days, the false operation is easy to happen and the false positive rate is relatively high. Compared with the defect of urine detection, the saliva detection has the advantages of being suitable for free drugs, easy to obtain saliva and harmless to collectors. Even if the saliva collector is an important part of the process, more and more products which meet the physiological characteristics of human bodies and meet the detection requirements are published.
Disclosure of Invention
The purpose of the invention is as follows: the invention aims to provide a saliva collector for drug detection and a matched mouthwash thereof, aiming at the defects of the prior art.
The technical scheme is as follows: the saliva collector for drug detection comprises a saliva collecting mechanism, wherein the saliva collecting mechanism comprises a saliva collecting port and a saliva collecting pipe connected to the saliva collecting port, a detachable gargle water bag and a clean water bag are hung on the side wall of the saliva collecting pipe, and sealing covers capable of being opened and closed repeatedly are arranged at openings of the gargle water bag and the clean water bag.
A mouthwash matched with a saliva collector for drug detection comprises the following components in parts by weight: 80 parts of water, 10 parts of citric acid, 5 parts of alcohol, 2 parts of xylitol, 1.5 parts of glycerol, 1 part of sorbitol and 0.5 part of mint extract.
Compared with the prior art, the invention has the following beneficial effects: the addition of suitable sialic acid to the mouthwash increases the salivary secretion of the subject, on the one hand, thereby increasing the accuracy and sensitivity of the test, and on the other hand, inhibits bacterial growth by reducing the ph of the sample, thereby extending the shelf life of the sample.
Drawings
FIG. 1 is a schematic structural diagram of a saliva collector for drug detection and a saliva collector portion in mouthwash fitted with the saliva collector according to the present invention.
In the figure: 1. a saliva collecting port; 2. a saliva collection tube; 3. a gargling water bag; 4. a clear water sac; 5. and (7) sealing the cover.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The technical solution of the present invention will be described in detail below with specific examples. The following several specific embodiments may be combined with each other, and details of the same or similar concepts or processes may not be repeated in some embodiments.
The utility model provides a poison detects uses saliva collector, collects the mechanism including saliva, saliva collection mechanism includes that saliva gathers mouthful 1 and connects saliva collecting pipe 2 on saliva collection mouthful 1, adds on saliva collecting pipe 2's the lateral wall and hangs detachable mouthwash bag 3 and clear water bag 4, and the opening part of mouthwash bag 3 and clear water bag 4 all is equipped with repeatedly the closing cap 5 of opening and close.
A mouthwash matched with a saliva collector for drug detection comprises the following components in parts by weight: 80 parts of water, 10 parts of citric acid, 5 parts of alcohol, 2 parts of xylitol, 1.5 parts of glycerol, 1 part of sorbitol and 0.5 part of mint extract.
The advantage of this solution is that the addition of suitable sialic acid to the mouthwash increases the salivary content of the subject, on the one hand, and thus the accuracy and sensitivity of the detection, and, on the other hand, due to the reduced ph in the sample, thereby inhibiting the growth of bacteria, prolonging the quality guarantee period of a sample, increasing the problem that glycerin can be used as a humectant to relieve the dryness of the oral cavity of a drug addict, pre-installing mouthwash in the mouthwash bag 3, additionally arranging a hanging clear water bag 4 on the side wall of the saliva collecting pipe 2, arranging sealing covers 5 which can be repeatedly opened and closed at the openings of the mouthwash bag 3 and the clear water bag 4, can spit the mouthwash 3 with the mouthwash after gargling in and cover closing cap 5, gargle with the clear water afterwards in order to avoid the mouthwash to influence the testing result, spit into clear water bag 4 and cover closing cap 5 after the clear water uses, avoid polluting the test environment, also avoid taking place the infectious diseases risk between testing personnel and the virus absorption personnel.
The technical proposal is to prepare 10 percent of citric acid in common mouthwash, so that the final pH value is between 3 and 4. Tests show that when ordinary people use our mouthwash, the salivary secretion rate is increased from 0.05ml/min to 1.5 ml/min. After the drug inhalation-induced xerostomia patient uses the invention, the salivary secretion rate is increased from-0.01 ml/min to-0.8 ml/min, and the salivary secretion rate is obviously increased, thereby facilitating the collection of saliva.
In the present invention, unless otherwise explicitly specified or limited, the first feature "on" or "under" the second feature may be directly contacting the first feature and the second feature or indirectly contacting the first feature and the second feature through an intermediate. Also, a first feature "on," "above," and "over" a second feature may mean that the first feature is directly above or obliquely above the second feature, or that only the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lower level than the second feature. In the description herein, reference to the description of the term "one embodiment," "some embodiments," "an example," "a specific example" or "some examples," or the like, means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example.
Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (2)
1. The utility model provides a narcotic drug is saliva collector for detection, includes saliva collection mechanism, its characterized in that: the saliva collecting mechanism comprises a saliva collecting port and a saliva collecting pipe connected to the saliva collecting port, a detachable mouth rinsing water bag and a detachable clear water bag are hung on the side wall of the saliva collecting pipe, and sealing covers capable of being opened and closed repeatedly are arranged at openings of the mouth rinsing water bag and the clear water bag.
2. The mouthwash of claim 1, wherein the saliva collector for drug testing is used with a mouth wash, the mouth wash comprising: the composite material comprises the following components in parts by weight: 80 parts of water, 10 parts of citric acid, 5 parts of alcohol, 2 parts of xylitol, 1.5 parts of glycerol, 1 part of sorbitol and 0.5 part of mint extract.
Priority Applications (1)
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CN202110862006.XA CN113520476A (en) | 2021-07-29 | 2021-07-29 | Drug detects uses saliva collector and complex mouthwash thereof |
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CN202110862006.XA CN113520476A (en) | 2021-07-29 | 2021-07-29 | Drug detects uses saliva collector and complex mouthwash thereof |
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CN113520476A true CN113520476A (en) | 2021-10-22 |
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CN202110862006.XA Withdrawn CN113520476A (en) | 2021-07-29 | 2021-07-29 | Drug detects uses saliva collector and complex mouthwash thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115737475A (en) * | 2022-10-21 | 2023-03-07 | 鉴诺生物科技(江苏)有限公司 | Antibacterial and humidifying mouthwash for drug detection and preparation method thereof |
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2021
- 2021-07-29 CN CN202110862006.XA patent/CN113520476A/en not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115737475A (en) * | 2022-10-21 | 2023-03-07 | 鉴诺生物科技(江苏)有限公司 | Antibacterial and humidifying mouthwash for drug detection and preparation method thereof |
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Application publication date: 20211022 |