CN113520434A - Energy spectrum rapid imaging cone-beam CT system suitable for small animals and design method - Google Patents

Energy spectrum rapid imaging cone-beam CT system suitable for small animals and design method Download PDF

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Publication number
CN113520434A
CN113520434A CN202110619601.0A CN202110619601A CN113520434A CN 113520434 A CN113520434 A CN 113520434A CN 202110619601 A CN202110619601 A CN 202110619601A CN 113520434 A CN113520434 A CN 113520434A
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imaging
unit
energy spectrum
cone
rotating
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CN113520434B (en
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牛田野
罗辰
王静
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Suzhou Dongying Information Technology Co ltd
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Suzhou Dongying Information Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computerised tomographs
    • A61B6/032Transmission computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/40Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4064Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
    • A61B6/4085Cone-beams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44Constructional features of apparatus for radiation diagnosis
    • A61B6/4429Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44Constructional features of apparatus for radiation diagnosis
    • A61B6/4429Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • A61B6/4452Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being able to move relative to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/508Clinical applications for non-human patients

Abstract

The invention discloses an energy spectrum fast imaging cone-beam CT system suitable for small animals and a design method thereof. And performing physical simulation according to the attribute information of the rotating equipment which rotates along with the rotating table and the rotating table to determine rotation parameters and selecting a driving unit adaptive to the rotation parameters, so that the driving unit can accurately drive the CT scanning imaging unit to rotate, and the multi-dimensional scanning of the test sample is realized. Control signals and collected data are processed by the single chip microcomputer and the onboard PC, so that the processing speed is high, and the safety is guaranteed. Based on this, the fast imaging cone beam CT system of energy spectrum that designs is got has higher efficiency than current little animal cone beam little CT, and higher resolution is clearly clear, can realize energy spectrum imaging, and the mobility is higher.

Description

Energy spectrum rapid imaging cone-beam CT system suitable for small animals and design method
Technical Field
The invention belongs to the field of CT imaging, and particularly relates to a cone-beam CT system for rapid spectral imaging of small animals and a design method thereof.
Background
Computed tomography spectral imaging is one of the research focuses in the CT field, and there are many existing cone-beam CT imaging systems, such as a multifunctional cone-beam CT imaging system disclosed in the patent application with publication number CN105167796A, and a freedom degree animal cone-beam CT imaging system disclosed in the patent application with publication number CN 107115120A. Compared with the traditional CT, the energy spectrum CT utilizes the difference of the absorption capacity of substances under different X-ray energies, can provide richer tissue resolution information than the conventional CT, and has a plurality of advantages of improving the image quality, inhibiting beam hardening artifacts, reducing the radiation dose and the like.
In the CT medical measurement and imaging technology of micro objects and living small animals, the small animal cone beam micro CT can very conveniently image mice and rats and can be widely applied to neurology, oncology, cardiovascular diseases and drug research and development.
Because the existing cone beam micro-CT scanning of the small animals has long time, the reconstruction quality is influenced by the scanning process, and three-energy imaging cannot be carried out, namely energy spectrum imaging cannot be realized, the requirements of improving the scanning speed and realizing energy spectrum imaging and quick reconstruction are common on the premise of ensuring the imaging quality.
In view of the above problems, there is an urgent need for a cone-beam CT system for fast spectral imaging of small animals.
Disclosure of Invention
In view of the above, the present invention aims to provide a cone-beam CT system for spectral fast imaging of small animals and a design method thereof, wherein the designed cone-beam CT system is light and convenient, and has the capabilities of fast scanning, high resolution, three-energy imaging and on-board PC on-site direct image reconstruction.
In order to achieve the above object, the present invention provides the following technical solutions:
in a first aspect, a method for designing a cone-beam CT system for fast spectral imaging of small animals includes the following steps:
selecting at least three groups of CT scanning imaging units with different emergent energy spectrums for energy spectrum imaging and a rotating platform with a middle through hole, and installing the CT scanning imaging units to be uniformly distributed on one side of the rotating platform;
a laser alignment unit composed of at least three lasers is arranged on the CT scanning imaging unit and the rotary table, and the CT scanning imaging unit is calibrated by the laser alignment unit;
performing physical simulation according to attribute information of a rotating assembly which is arranged on the rotating platform and rotates along with the rotating platform to determine rotating parameters, and selecting a rotating driving unit which is adaptive to the rotating parameters and installing the rotating driving unit on the other side of the rotating platform;
designing control parameters of a CT scanning imaging unit and a rotary driving unit according to the imaging requirements of a cone beam CT system, compiling control instructions according to the control parameters and burning the control instructions into a single chip microcomputer;
select inclinometer and fixed mounting to revolving stage, select board to carry PC and demountable installation to the opposite side of revolving stage, select the singlechip and install to the stator end of rotation driving unit, walk the line and connect CT scanning imaging unit, inclinometer and board and carry PC to stator end singlechip through hollow sliding ring.
Preferably, each set of CT scanning imaging units includes a generator and a detector, wherein the generator is used for emitting X-rays, the detector is used for receiving X-ray signals transmitted by the imaging sample, and the generator and the detector are distributed at two ends of the middle diameter of the table top of the rotating table.
Preferably, the laser alignment unit includes three line lasers, wherein two line lasers are respectively disposed on the generator and the detector of the set of CT scanning imaging unit, the other line laser is disposed at the center of the rotary table, an intersection point where laser beams emitted by the three line lasers converge is used as an origin of coordinates of the calibration coordinates, and the generator and the detector belonging to the same CT scanning imaging unit are calibrated by using the calibration coordinates, so that a center of a light beam emitted by the generator is aligned with the origin of coordinates.
Preferably, the calibration coordinate system constructed by the laser collimation unit is also used as a positioning reference for the test sample to be placed at the scanning center.
Preferably, the attribute information of the rotating assembly includes: the weight and the gravity center of an imaging component, the weight and the gravity center of a rotating platform rotor end and the weight and the gravity center of an inclinometer which are included in the CT scanning imaging unit;
the rotation parameters comprise rotational inertia and rotational speed.
Preferably, the driving unit comprises a hollow rotary bearing, a servo motor and a servo motor driver, the rotary table is mounted at the rotor end of the hollow rotary bearing, the servo motor is mounted at the other side of the hollow rotary bearing, the servo motor driver is connected to the servo motor and the single chip microcomputer through cables, and the single chip microcomputer drives the servo motor by controlling the servo motor driver;
the single chip microcomputer controls the frequency of trigger signals of a generator and a detector in the CT scanning imaging unit so as to control the generator and the detector to work synchronously; the single chip microcomputer controls the rotating speed and the rotating period of the servo motor in the driving unit.
Preferably, the onboard PC serves as an imaging processing unit, receives projection data acquired by the CT scanning imaging unit and angle data acquired by the inclinometer through a network cable, and performs energy spectrum imaging based on the received projection data and angle data;
the onboard PC is used as an imaging processing unit, a reconstructed image obtained through energy spectrum imaging is output to connected external equipment through a network cable integrated into the slip ring, and remote control of the external equipment on the imaging processing unit is received.
Preferably, a hollow annular imaging unit of another modality is designed and installed on the other side of the rotating platform opposite to the CT scanning imaging unit, the test sample is conveyed to an operation space of the hollow annular imaging unit on the other side of the rotating platform through a middle through hole of the rotating platform, and imaging of the other modality is performed by using the hollow annular imaging unit.
Preferably, a two-way emergency stop switch is designed for the energy spectrum fast imaging cone beam CT system and is used for controlling the generator and the servo motor controller to simultaneously and emergently stop working;
an X-ray radiation shielding shell is designed for the energy spectrum fast imaging cone-beam CT system and is used for preventing the X-rays emitted by the generator from emitting outwards.
In a second aspect, the spectral fast imaging cone-beam CT system suitable for small animals is designed according to the method of the first aspect.
Compared with the prior art, the technical scheme provided by the invention has at least the following effects:
by selecting CT scanning imaging units with different emergent energy spectrums and comprising generators and detectors to obtain scanning signals, various requirements and use environments of three-energy-spectrum imaging can be met. The method has the advantages that physical simulation is carried out according to the attribute information of the rotary table and the rotor end assembly rotating along with the rotary table to determine the rotation parameters, and the driving unit adaptive to the rotation parameters is selected, so that the driving unit can drive the CT scanning imaging unit to rotate stably with high precision, multi-dimensional scanning of a test sample is realized, and jitter and control error suppression are avoided. Control signals and collected data are processed by the single chip microcomputer and the onboard PC, so that the processing speed is high, and the safety is guaranteed. Based on this, the fast imaging cone beam CT system of energy spectrum that designs is got has higher efficiency than current little animal cone beam little CT, and higher resolution is clearly clear, can realize energy spectrum imaging, and the mobility is higher.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a flow chart of a design method of a spectral fast imaging cone-beam CT system suitable for small animals provided by the embodiment;
FIG. 2 is a schematic structural diagram of a cone-beam CT system for spectral fast imaging of small animals according to an embodiment;
in FIG. 2, 1-generator, 2-laser, 3-detector, 4-onboard PC, 5-rotating platform, 6-inclinometer, 7-hollow slewing bearing, 8-slip ring, 9-servo motor, 10-servo motor driver, 11-single chip microcomputer, 12-shielding shell, 13-emergency stop switch.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the detailed description and specific examples, while indicating the scope of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
The existing cone beam micro CT scanning of the small animal has long time and can not rotate, when three-energy imaging is carried out, the detection data for the three-energy imaging can be obtained only by adjusting scanning for many times, the time consumption is long, and when the cone beam micro CT scanning is used for in-vivo imaging, complex motion monitoring is also required to be carried out so as to ensure that the motion error of a sample is compensated between the three times of scanning and imaging. In order to solve the problem, the embodiment of the invention provides a design method of a spectral fast imaging cone-beam CT system suitable for small animals. As shown in fig. 1 and 2, the embodiment provides a design method of a cone-beam CT system for spectral fast imaging of small animals, comprising the following steps:
step 1, selecting at least three groups of CT scanning imaging units with different emergent energy spectrums for energy spectrum imaging and a rotating platform 5 with a middle through hole, and installing the CT scanning imaging units to be uniformly distributed on one side of the rotating platform 5.
In order to realize three-energy imaging, a plurality of groups of CT scanning imaging units can be selected to emit X rays with different energy spectrums, in the embodiment, different voltages can be set through three groups of generators or light outlet stoppers are added to realize different emitted energy spectrums, and then three-dimensional reconstruction is carried out according to the acquired X-ray projection drawing to obtain a reconstructed image.
In the embodiment, a rotating platform 5 with a through hole in the center is selected, the detection units are uniformly distributed on one side of the rotating platform 5, the rotating platform 5 can continuously rotate, and the CT scanning imaging unit mounted on the rotating platform is driven to continuously detect a test sample to obtain a scanning detection signal for three-energy imaging. In addition, the middle through hole of the rotating platform 5 provides a transportation channel for directly conveying the test sample from one side of the rotating platform 5 to the other side, so that multi-mode measurement is realized.
Each group of CT scanning imaging units comprises a generator 1 and a detector 3, wherein the generator 1 is used for emitting X-rays, the detector 3 is used for receiving the X-rays of the transmission imaging sample, and the generator 1 and the detector 3 are distributed at two ends of the surface middle diameter of the rotating platform 5. Alternatively, the generator 1 may employ an X-ray tube, and the detector 3 may be a flat panel detector 3 consisting of a deposited scintillator material and a photodiode. In the embodiment, the diameter of the surface of the rotating platform 5 passing through the center point is taken as the middle diameter of the surface of the rotating platform 5, and the generator 1 and the detector 3 are distributed at two ends of the middle diameter of the surface of the rotating platform 5, so that the X-ray emitted by the generator 1 can be received by the detector 3. Optionally, three sets of CT scanning imaging units may be selected, each set of CT scanning imaging units is uniformly arranged and fixed on the surface of the rotating table 5 in an angle of 120 °, and the three sets of CT scanning imaging units realize detection of three different energy spectrums, so as to obtain three sets of X-ray projection views with different energies.
And 2, mounting a laser alignment unit consisting of at least two line lasers 2 on the CT scanning imaging unit and the rotary table 5, and mounting and calibrating the CT scanning imaging unit by using the laser alignment unit.
In order to make the relative positions of the generator 1 and the detector in the installed CT scanning imaging unit accurate, so as to realize accurate acquisition of scanning detection signals, the CT scanning imaging unit needs to be subjected to position calibration during installation. In the embodiment, the position calibration of the CT scanning imaging unit is realized by adopting a laser alignment unit consisting of at least two line lasers 2.
In one embodiment, when the line laser 2 is a line laser or a cross line laser, the laser alignment unit may include three line lasers 2, wherein two line lasers 2 are respectively disposed on the generator 1 and the detector 3 of the CT scanning imaging unit, another line laser 2 is disposed at the center of the rotary table 5, an intersection point where laser beams emitted from the three line lasers 2 converge is used as an origin of coordinates of the alignment coordinates, three laser lines are respectively used as three coordinate axes of the three alignment coordinates, and the generator 1 and the detector 3 belonging to the same CT scanning imaging unit are aligned by using the alignment coordinates, so that the center of an X-ray beam emitted from the generator 1 is aligned with the origin of coordinates. I.e. the scan center position is determined by the laser alignment unit.
In an embodiment, when the line laser 2 is a cross line laser, the laser alignment unit may include two line lasers 2, wherein the two line lasers 2 are respectively disposed on the generator 1 and the detector 3 of the set of CT scanning imaging unit, of course, one of the line lasers 2 may also be disposed on the generator 1 or the detector 3 of the set of CT scanning imaging unit, the other line laser 2 is disposed at the center of the rotary table, an intersection point where the laser beams emitted by the two line lasers converge is used as a coordinate origin of the calibration coordinate, and the generator and the detector belonging to the same CT scanning imaging unit are calibrated by using the calibration coordinate, so that the center of the light beam emitted by the generator is aligned with the coordinate origin.
Besides being used for the position calibration of the CT scanning imaging unit, the laser alignment unit also serves as a calibration coordinate system constructed by the laser alignment unit to be used as a calibration reference for placing the test sample at the scanning center position. When the test sample, in order to realize the accurate detection to the test sample, need put the test sample to scanning central point and put, the laser intersection point that the laser alignment unit that the embodiment provided produced puts as scanning central point and puts, for putting the test sample as the reference of putting, has promoted the speed of putting of test sample greatly.
And 3, performing physical simulation according to the attribute information of the rotating assembly which is arranged on the rotating platform 5 and rotates along with the rotating platform 5 to determine a rotation parameter, and selecting a rotation driving unit which is matched with the rotation parameter and installing the rotation driving unit on the other side of the rotating platform 5.
When designing a rotation driving unit for driving the rotation of the rotation platform 5, in order to realize normal rotation of the rotation platform 5 and save driving resources, physical simulation is performed on a rotation process before the rotation driving unit is selected, rotation parameters of the rotation process are calculated through simulation, and an adaptive rotation driving unit is selected according to the rotation parameters.
In an embodiment, the rotating assembly arranged on the rotating table 5 and rotating together with the rotating table 5 comprises the imaging equipment comprised by the CT scan imaging unit, such as the generator 1 and the detector 3 receiving X-rays, the weight and the center of gravity of the rotor end of the rotating table, the inclinometer 6 arranged on the rotating table 5, and when additional test modes are added, the equipment implementing the additional test modes and mounted on the rotating table 5.
Based on this, the attribute information of the rotating device includes: the CT scan imaging unit includes the weight and center of gravity of the imaging apparatus, the weight and center of gravity of the turntable 5, and the weight and center of gravity of the inclinometer. And performing physical simulation according to the weight and the gravity center of the equipment to determine rotation parameters, wherein the rotation parameters comprise the moment of inertia and the rotating speed.
The rotary driving unit comprises a hollow rotary bearing 7, a servo motor 9 and a servo motor driver 10, the rotary table 5 is mounted at the rotor end of the hollow rotary bearing 7, the servo motor 9 is mounted at the other side of the hollow rotary bearing 7, the servo motor driver 10 is connected to the servo motor 9 and a single chip microcomputer 11 through cables, and the single chip microcomputer 11 drives the servo motor 9 by controlling the servo motor driver 10.
In the rotary drive unit, a servo motor 9 is fixed to the stator end of the hollow rotary bearing 7 as a main execution rotary member, does not rotate with the rotary table 5, is driven by a servo motor driver 10, and is not in the scanning field of view. The rotation speed and the rotation period of the servo motor 9 are controlled by a single chip microcomputer 11.
And 4, designing control parameters of the CT scanning imaging unit and the rotation driving unit according to the imaging requirements of the cone beam CT system, compiling control instructions according to the control parameters and burning the control instructions into the single chip microcomputer 11.
In order to realize the non-interference control of the CT scanning imaging unit and the rotary driving unit, the control parameters of the CT scanning imaging unit and the rotary driving unit are designed in advance according to the imaging requirement of the cone beam CT system, and the control parameters are programmed into the singlechip 11 by a programming layer control instruction, so that when the control parameters are applied, the control instructions are output to the CT scanning imaging unit and the driving unit to control the work of the two units. Alternatively, the single chip microcomputer 11 may be an ARM single chip microcomputer.
Aiming at the CT scanning imaging unit, the single chip microcomputer 11 controls the frequency of trigger signals of the generator 1 and the detector 3 in the CT scanning imaging unit so as to control the generator 1 and the detector 3 to work synchronously. For the driving unit, the single chip 11 controls the rotation speed and the rotation period of the servo motor 9 in the driving unit.
And 5, selecting an inclinometer 6, fixedly installing the inclinometer to the rotating platform 5, selecting an onboard PC4, detachably installing the onboard PC4 to the other side of the rotating platform 5, selecting a single chip microcomputer 11, installing the single chip microcomputer to the stator end, and connecting the CT scanning imaging unit, the inclinometer, the onboard PC4 and other rotating platform onboard components to the stator end single chip microcomputer 11 through a hollow slip ring 8 in a wiring mode.
The inclinometer 6 is used to acquire angle data of the rotating table 5, which is used for three-dimensional reconstruction together with projection data (scan detection signals) acquired by the CT scan imaging unit. The inclinometer can be fixedly arranged on the side surface of the rotating platform 5, so that the scanning working space of the test sample is not occupied, and the scanning of the test sample is not influenced.
An on-board PC4 is directly detachably mounted on the other side of the rotation stage 5 as part of the system, i.e. the non-working space for CT scan imaging. Because the cost of on-board PC4 is low, when the processing capacity needs to be increased, one on-board PC4 can be directly replaced, and other components of the system do not need to be moved, so that the system is convenient to maintain.
In order to match the rotation of the hollow rotating platform 5 and realize continuous measurement of rotation, the CT scanning imaging unit and an onboard PC4(personal computer) are connected through a network cable, and the inclinometer and the onboard PC4 are connected at the same time, so that the onboard PC4 is connected with the CT scanning imaging unit and the inclinometer, and projection data and angle data can be received in real time. In the embodiment, the CT scanning imaging unit and the single chip microcomputer 11 are connected through a hollow slip ring 8 in a wiring mode.
In the embodiment, the onboard PC4 is used as an imaging processing unit, projection data acquired by the CT scanning imaging unit and angle data acquired by the inclinometer are received through a network cable, and energy spectrum imaging is performed based on the received projection data and angle data, so that the energy spectrum imaging is directly performed on the projection data and the angle data through the imaging processing unit carried by the system, the data transmission quantity is reduced, the speed and the real-time performance of acquiring a reconstructed image are improved, and remote control is realized.
In the embodiment, the onboard PC4 is used as an imaging processing unit, and the reconstructed image obtained through energy spectrum imaging is output to the connected external device through the network cable integrated in the slip ring 7, so as to receive the remote control of the external device on the imaging processing unit.
In the above design method, a hollow annular imaging unit of another modality is further designed and installed on the other side of the rotating platform 5 opposite to the CT scanning imaging unit, the test sample is conveyed to an operation space of the hollow annular imaging unit on the other side of the rotating platform 5 through a middle through hole of the rotating platform 5, and the hollow annular imaging unit is used for imaging of the other modality.
In the design method, a two-way emergency stop switch 13 is designed for the energy spectrum fast imaging cone beam CT system and is used for controlling the generator 1 and the servo motor driver 10 to stop working emergently at the same time. When an emergency occurs during the test, the X-ray emitted from the generator 1 is prevented from injuring the human body, and the servo motor driver 10 is prevented from driving the rotating platform 5 to rotate through the servo motor 9 and the hollow rotary bearing 7, so that the potential safety hazard to the human body is prevented.
In the above design method, the X-ray radiation shielding housing 12 is designed for the energy spectrum fast imaging cone beam CT system, and is used to prevent the X-rays emitted from the generator 1 from emitting outwards. Alternatively, the shield case 12 may employ a lead material.
Compared with the existing small animal cone beam micro CT, the energy spectrum fast imaging cone beam CT system designed based on the design method has higher efficiency, higher resolution, capability of realizing energy spectrum imaging and higher mobility.
The above-mentioned embodiments are intended to illustrate the technical solutions and advantages of the present invention, and it should be understood that the above-mentioned embodiments are only the most preferred embodiments of the present invention, and are not intended to limit the present invention, and any modifications, additions, equivalents, etc. made within the scope of the principles of the present invention should be included in the scope of the present invention.

Claims (10)

1. A design method of a cone-beam CT system suitable for spectral fast imaging of small animals is characterized by comprising the following steps:
selecting at least three groups of CT scanning imaging units with different emergent energy spectrums for energy spectrum imaging and a rotating platform with a middle through hole, and installing the CT scanning imaging units to be uniformly distributed on one side of the rotating platform;
a laser alignment unit consisting of at least two line lasers is arranged on the CT scanning imaging unit and the rotary table, and the CT scanning imaging unit is aligned by the laser alignment unit;
performing physical simulation according to attribute information of a rotating assembly which is arranged on the rotating platform and rotates along with the rotating platform to determine rotating parameters, and selecting a rotating driving unit which is adaptive to the rotating parameters and installing the rotating driving unit on the other side of the rotating platform;
designing control parameters of a CT scanning imaging unit and a rotary driving unit according to the imaging requirements of a cone beam CT system, compiling control instructions according to the control parameters and burning the control instructions into a single chip microcomputer;
select inclinometer and fixed mounting to revolving stage, select board to carry PC and demountable installation to the opposite side of revolving stage, select the singlechip and install to the stator end of rotation driving unit, walk the line and connect CT scanning imaging unit, inclinometer and board and carry PC to stator end singlechip through hollow sliding ring.
2. The method as claimed in claim 1, wherein each set of CT scanning imaging units comprises a generator and a detector, wherein the generator is used for emitting X-rays, the detector is used for receiving X-ray signals after transmission of the imaging sample, and the generator and the detector are distributed at two ends of the middle diameter of the rotary table.
3. The design method of the energy spectrum fast imaging cone beam CT system suitable for the small animal according to claim 2, characterized in that the laser alignment unit comprises three line lasers, wherein two line lasers are respectively arranged on the generator and the detector of a set of CT scanning imaging unit, the other line laser is arranged at the center of the rotating table, the intersection point of the convergence of the laser emitted by the three line lasers is used as the origin of coordinates of the calibration coordinates, and the generator and the detector belonging to the same CT scanning imaging unit are calibrated by using the calibration coordinates, so that the center of the light beam emitted by the generator is aligned with the origin of coordinates.
4. The design method of the cone-beam CT system for the fast imaging of energy spectrum of small animals as claimed in claim 1 or 3, wherein the calibration coordinate system constructed by the laser collimation unit is also used as the positioning reference for the test sample to be placed at the scan center position.
5. The design method of the cone-beam CT system for spectral fast imaging of small animals according to claim 1, wherein the attribute information of the rotating assembly comprises: the weight and the gravity center of an imaging component, the weight and the gravity center of a rotating platform rotor end and the weight and the gravity center of an inclinometer which are included in the CT scanning imaging unit;
the rotation parameters comprise rotational inertia and rotational speed.
6. The design method of the cone-beam CT system for spectral fast imaging of small animals as claimed in claim 1 or 2, wherein the driving unit comprises a hollow rotary bearing, a servo motor driver, the rotary table is installed at the rotor end of the hollow rotary bearing, the servo motor is installed at the other side of the hollow rotary bearing, the servo motor driver is connected to the servo motor and the single chip microcomputer through cables, the single chip microcomputer drives the servo motor by controlling the servo motor driver;
the single chip microcomputer controls the frequency of trigger signals of a generator and a detector in the CT scanning imaging unit so as to control the generator and the detector to work synchronously; the single chip microcomputer controls the rotating speed and the rotating period of the servo motor in the driving unit.
7. The design method of the energy spectrum fast imaging cone beam CT system suitable for the small animal according to claim 1, characterized in that the on-board PC is used as an imaging processing unit, receives the projection data collected by the CT scanning imaging unit and the angle data collected by the inclinometer through a network cable, and performs energy spectrum imaging based on the received projection data and angle data;
the onboard PC is used as an imaging processing unit, a reconstructed image obtained through energy spectrum imaging is output to connected external equipment through a network cable integrated into the slip ring, and remote control of the external equipment on the imaging processing unit is received.
8. The method as claimed in claim 1, wherein a hollow ring-shaped imaging unit of other modality is installed on the other side of the rotating platform opposite to the CT scanning imaging unit, the test sample is transported to the operation space of the hollow ring-shaped imaging unit on the other side of the rotating platform through the middle through hole of the rotating platform, and the hollow ring-shaped imaging unit is used for imaging of other modality.
9. The design method of the energy spectrum fast imaging cone beam CT system suitable for the small animals according to any one of claims 2 to 8, characterized in that a two-way emergency stop switch is designed for the energy spectrum fast imaging cone beam CT system, and is used for controlling the generator and the servo motor controller to simultaneously and emergently stop working;
an X-ray radiation shielding shell is designed for the energy spectrum fast imaging cone-beam CT system and is used for preventing the X-rays emitted by the generator from emitting outwards.
10. An energy spectrum fast imaging cone-beam CT system suitable for small animals, which is characterized in that the energy spectrum fast imaging cone-beam CT system is designed according to the design method of any one of claims 1-9.
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