CN113519631A - Middle-aged and old modified milk powder assisting in reducing blood sugar and having low blood sugar load and preparation method thereof - Google Patents
Middle-aged and old modified milk powder assisting in reducing blood sugar and having low blood sugar load and preparation method thereof Download PDFInfo
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- CN113519631A CN113519631A CN202110764055.XA CN202110764055A CN113519631A CN 113519631 A CN113519631 A CN 113519631A CN 202110764055 A CN202110764055 A CN 202110764055A CN 113519631 A CN113519631 A CN 113519631A
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- blood sugar
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- powder
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
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- A23C21/08—Whey; Whey preparations containing other organic additives, e.g. vegetable or animal products
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
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- A23C21/10—Whey; Whey preparations containing inorganic additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23V2400/51—Bifidobacterium
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- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
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Abstract
The invention discloses middle-aged and elderly modified milk powder with hypoglycemic load for assisting blood sugar reduction and a preparation method thereof, belonging to the technical field of modified milk powder preparation. The modified milk powder comprises modified milk base powder, low-load polysaccharide dietary fiber, a vitamin composition, a mineral composition, a blood sugar-reducing functional composition and bifidobacterium animalis Bb-12. The invention inhibits the absorption and conversion of sucrose in vivo into glucose by adding various polysaccharide dietary fibers such as L-arabinose, resistant dextrin and the like, and obviously reduces the blood glucose generation index and the blood glucose load value after drinking; the blood sugar reducing functional compositions such as moringa oleifera leaf powder and wheat oligopeptide and the low-load polysaccharide dietary fiber generate a synergistic effect, and the blood sugar reducing functional compositions can play a role in assisting in reducing blood sugar after being taken for a long time. The invention not only can meet the nutritional requirements of consumers on the intake of dairy products, but also has lower blood sugar load, has wider intake population compared with the conventional modified milk powder, and is more beneficial to middle-aged and elderly people suffering from obesity, hyperglycemia and the like.
Description
Technical Field
The invention relates to middle-aged and old modified milk powder assisting in reducing blood sugar and a preparation method thereof, belonging to the technical field of modified milk powder preparation.
Background
According to the latest data display of Chinese resident nutrition and chronic disease state report (2020) and healthy Chinese & 2020 health physical examination white paper diabetes prevention and control report, more than half of adults in China are overweight or obese; there are 1.298 billion adults with diabetes, the "first" worldwide, with an average of 1 diabetic per 10. Moreover, the risk probability of obesity and diabetes gradually increases with the age, and obesity and diabetes may cause other complications such as cardiovascular and cerebrovascular diseases and organ failure, which not only causes mental and physical injuries to patients, but also may cause adverse effects on social and national development.
Aiming at the two groups of people, weight is controlled or blood sugar is reduced by adopting weight-losing medicines, diet control, insulin injection and other modes at present, so that the food which can provide nutrition energy, remarkably reduce carbohydrate intake and inhibit the blood sugar from greatly increasing is important. The glycemic index and the glycemic load are usually used for reflecting the influence of carbohydrates in food on blood glucose concentration, and food with higher glycemic index and glycemic load can be converted into more fat in a human body after being eaten for a long time to form fat accumulation, so that the diabetic symptoms caused by sugar metabolism disorder are more likely to be caused. The consumption of food with low glycemic index and blood sugar load not only has less absorption burden to human body, but also can obviously reduce the probability of adverse conditions, reduce the conversion and absorption of disaccharide after being eaten by obese or diabetic patients, and greatly improve the insulin secretion or utilization degree.
Therefore, an in-depth search of glycemic index and glycemic load will allow the search for optimal food for obese or diabetic patients. In the modified milk powder category of food products, the milk powder can modulate a variety of nutritionally abundant, specifically functional and digestive substances in the gastrointestinal tract, and the inclusion of lactose in the milk powder in an amount that also has a lower glycemic index will result in a lower glycemic load. In conclusion, the hypoglycemic load modified milk powder which is rich in nutrition, high in functionality and low in price is developed for a plurality of consumers and even obese and hyperglycemic people, and is more beneficial to the public demand.
Disclosure of Invention
The invention aims to provide a formula of modified milk powder for middle-aged and elderly people with low blood sugar load for assisting in reducing blood sugar, so as to solve the problem that the blood sugar generation index and the blood sugar load of the people are greatly increased after the people ingest food, reduce the possibility of fat accumulation and play a role in assisting in reducing blood sugar.
The technical scheme of the invention is as follows:
the middle-aged and old modified milk powder assisting in reducing blood sugar and blood sugar load comprises the following raw materials in parts by weight: 748-858 parts of blended milk base powder, 115-215 parts of low-load polysaccharide dietary fiber, 2.5-3.5 parts of a vitamin composition, 19-21 parts of a mineral composition, 3-15 parts of a blood sugar reducing functional composition and 0.04 part of bifidobacterium animalis Bb-120.01.
Further limited, the protein content of the milk powder is not less than 17.3g/100g, the fat content is not less than 9.0g/100g, the vitamin A content is 300-900 mu g/100g, the vitamin D content is 6.3-12.5 mu g/100g, the vitamin E content is 10-31 mg/100g, and the vitamin C content is 30-100 mg/100 g.
Further limiting, the calcium content of the milk powder is not higher than 1200mg/100g, the iron content is 6-20 mg/100g, the zinc content is 3-6 mg/100g, and the selenium content is 14-28 mg/100 g.
Further limit, the content of Bifidobacterium animalis Bb-12 in the milk powder is not less than 8 x 106CFU/g。
Further limiting, the blended milk base powder is one or more of skimmed milk powder, concentrated whey protein powder and high oil whey powder, and is mixed according to any proportion.
Further limit, the low-load polysaccharide dietary fiber is one or more than two of isomaltose hypgather, isomaltitol, L-arabinose, inulin and resistant dextrin which are mixed according to any proportion.
Further, the vitamin composition is one or more than two of retinyl acetate, cholecalciferol, dl-alpha-tocopherol acetate and L-sodium ascorbate which are mixed according to a certain proportion.
Further limited, the mineral composition is one or more of calcium carbonate, ferrous sulfate, zinc sulfate and sodium selenite which are mixed according to a certain proportion.
Further limiting, the blood sugar reducing functional composition is one or more than two of wheat oligopeptide, moringa oleifera leaf powder, yam powder and mulberry leaf extract which are mixed according to any proportion.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in reducing blood sugar comprises the following steps:
step 1, mixing raw and auxiliary materials with milk base powder, low-load polysaccharide dietary fiber, a vitamin composition, a mineral composition, a blood sugar-reducing functional composition and an animal bifidobacterium Bb-12, carrying out air shower dedusting sterilization, and removing an outer package after sterilization;
and (3) sterilization treatment conditions: the air shower and sterilization time is 90 s; ultraviolet intensity is more than or equal to 140 mu W/cm2；
Step 2, weighing the raw and auxiliary materials subjected to the bag-removing and sterilizing treatment in the step 1, weighing the raw and auxiliary materials according to the proportion of the formula of the product, and sieving the raw and auxiliary materials;
step 3, carrying out on-line premixing on the raw and auxiliary materials processed in the step 2;
the premixing condition is as follows: the mixing time is 240s, and the premixing pressure is 0.20-0.4 MPa;
step 4, dry mixing the premix obtained in the step 3 to obtain a finished product;
dry mixing conditions: dry mixing time 320 s;
step 5, taking a finished product for metal detection;
removing the diameter of foreign matters: iron is more than or equal to 1.5mm, nonferrous is more than or equal to 2.0mm, and stainless steel is more than or equal to 2.0 mm.
The invention has the following beneficial effects: the invention relates to functional modified milk powder for middle-aged and elderly people with low blood sugar load, which is prepared by compounding and matching low-load polysaccharide dietary fiber, a blood sugar reducing functional composition and bifidobacterium animalis Bb-12 according to a certain proportion. The modified milk powder has the following advantages:
(1) the low-load polysaccharide dietary fiber adopted by the invention comprises functional polysaccharide, sugar alcohol and water-soluble dietary fiber, the polysaccharide and the sugar alcohol can equivalently replace sucrose in a human body, and the L-arabinose can also directly inhibit the metabolism and absorption of the sucrose, so that the blood sugar value is rapidly reduced, and the condition of high blood sugar load is effectively improved. And the water-soluble dietary fiber is proved to slowly release energy after being eaten, is carbohydrate which cannot be digested by a human body, is beneficial to reducing the blood sugar concentration and assisting in blood sugar reduction treatment, improves the diabetes symptoms, is easy to generate satiety, and reduces the occurrence probability of obesity. The polysaccharide and the dietary fiber play a role in synchronously reducing the blood sugar generation of a human body, and respectively inhibit the absorption of cane sugar in the stomach and the small intestine and slowly release carbohydrate, thereby further reducing the blood sugar generation.
(2) The blood sugar reducing functional composition adopted by the invention is a compound composition of medicinal and edible substances and new resource food, contains various physiological active factors, can be used as special nutrient substances, can effectively reduce the blood sugar concentration of a diabetic patient after being eaten for a long time, and has excellent health care effect when being matched with low-load functional dietary fibers. The probiotics can also accelerate gastrointestinal peristalsis and metabolism, and effectively utilize energy converted by sugar metabolism.
(3) The low-load polysaccharide dietary fiber and the blood sugar reducing functional composition are matched in a good proportion to be synergistic, so that the blood sugar load is effectively reduced, the problem of poor functionality of the conventional modified milk powder is solved, and the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition are beneficial to reducing blood sugar of a diabetic patient and reducing weight of obese people after being eaten for a long time, provide effective nutrient substances and have good effects.
Drawings
FIG. 1 is a graph comparing the blood glucose concentration after drinking different milk powders.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The experimental procedures used in the following examples are conventional unless otherwise specified. The materials, reagents, methods and apparatus used, unless otherwise specified, are conventional in the art and are commercially available to those skilled in the art.
The formula of the modified milk powder for middle-aged and old people with hypoglycemic load for assisting in reducing blood sugar provided by the invention comprises the following raw materials: blending milk base powder, low-load polysaccharide dietary fiber, a vitamin composition, a mineral composition, a blood sugar-reducing functional composition and animal bifidobacterium Bb-12.
Wherein, blending the milk base powder: research shows that the desalted whey powder and the skimmed milk powder respectively contain about 80% and 50% of lactose, so that the skimmed milk powder, the concentrated whey protein powder and the high-oil whey powder are reasonably matched, the content of the lactose is lower than 35g/100g, and the proportion of the protein and the fat is balanced to prepare the blended milk base powder. The high-quality nutrient is provided, and simultaneously, the lactose intake is reduced to the maximum extent, and the blood sugar content rise is reduced.
Low-load polysaccharide dietary fiber: the low-load functional dietary fiber comprises a polysaccharide, a sugar alcohol, and a carbohydrate. The isomaltooligosaccharide and the L-arabinose are low-load polysaccharides and have lower calories, wherein the Pueraria and other experiments show that the isomaltooligosaccharide is allosteric maltose, generates allosteric glucose after hydrolysis, only takes part in sugar metabolism in a small amount, and belongs to foods with low glycemic indexes; after the L-arabinose is taken in, protease for degrading the sucrose is influenced, so that the sucrose catabolism can be blocked, and the sucrose absorption can be inhibited. The isomaltitol is functional sugar alcohol, can replace sucrose in the food in an equivalent manner, lowers the blood concentration to the maximum extent, also greatly ensures the taste of the food, namely increases the sweetness, and can effectively promote the growth and the reproduction of beneficial bacteria in the human body and promote the gastrointestinal motility and the digestion. The inulin and the resistant dextrin are water-soluble dietary fibers, can generate less heat after being ingested, are beneficial to reducing fat and losing weight, relaxing bowel and improving the symptoms of diabetes, and can not cause the rapid rise of blood sugar after being eaten. Angela G, Colantonio, MateoGallego Roc i o, Linsene and the like show that the dietary fiber can effectively reduce the glycemic index, can reduce the blood glucose concentration after being taken for a long time, and can improve the symptoms of diabetes.
Functional composition for reducing blood sugar: the Chinese yam powder and the mulberry leaf extract are medicinal and edible substances with strong efficacy, contain more physiological active substances, can improve sleep, nourish and build body after being eaten for a long time, have slower blood sugar generation index and blood sugar load value, are more beneficial to preventing and treating diseases such as hyperlipidemia, hyperglycemia, obesity and the like, and do not cause adverse effects on human bodies through clinical display of the medicinal and edible substances. Wheat oligopeptide and moringa leaves are concerned by the food industry as new resource food, and because the multifunctionality of the wheat oligopeptide and the moringa leaves is gradually applied to foods such as baking foods and pastries, the wheat oligopeptide and the moringa leaves both have the characteristics of reducing high blood pressure, high blood lipid and high blood sugar and the efficacy of expelling toxin and losing weight, wherein the moringa leaves as pure natural green food contain all nutrient substances required by human bodies, and the moringa leaves are also considered to be capable of preventing more than 300 diseases by Indian herbals and are known as 'plant diamonds'.
The bifidobacterium animalis Bb-12 is the most commonly used probiotic in the current food processing, has proved to have excellent protective effect on the microenvironment of the gastrointestinal tract and the immune function, has stronger stability, has synergistic effect with the functional composition for reducing blood sugar, and promotes the conversion and metabolism of sugar.
Example 1:
the middle-aged and elderly modified milk powder for assisting in reducing blood glucose and lowering blood glucose load in the embodiment is prepared from the following raw materials in parts by weight:
857.49 parts of blended milk base powder, 115 parts of low-load polysaccharide dietary fiber, 3.5 parts of vitamin composition, 21 parts of mineral composition, 3 parts of hypoglycemic functional composition and 3 parts of animal bifidobacterium Bb-120.01 parts.
Wherein the blended milk base powder comprises 26% of skimmed milk powder, 19% of concentrated whey protein powder and 55% of high oil emulsion powder, which total 100%;
the low-load polysaccharide dietary fiber comprises 78% of isomaltose hypgather, 13% of isomaltitol, 5% of L-arabinose and 4% of resistant dextrin, and the total amount is 100%;
the vitamin composition comprises 0.55% of vitamin A, 0.00875% of vitamin D, 19.6% of vitamin E and 35.54% of vitamin C, wherein 55.70% of vitamin A and 44.30% of vitamin D are maltodextrin as auxiliary materials;
the mineral composition comprises 34.28% of calcium carbonate, 0.52% of ferrous sulfate, 0.32% of zinc sulfate and 1.02% of sodium selenite, wherein 36.14% of the total amount and 63.86% of maltodextrin are used as auxiliary materials;
the blood sugar reducing functional composition comprises 33.3% of wheat oligopeptide, 33.3% of moringa oleifera leaf powder, 16.7% of yam powder and 16.7% of mulberry leaf extract, wherein the total content is 100%.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting blood sugar reduction in the embodiment comprises the following steps:
step 1, mixing raw and auxiliary materials with milk base powder, low-load polysaccharide dietary fiber, a vitamin composition, a mineral composition, a blood sugar-reducing functional composition and an animal bifidobacterium Bb-12, carrying out air shower dedusting sterilization, and removing an outer package after sterilization;
and (3) sterilization treatment conditions: the air shower and sterilization time is 90 s; ultraviolet intensity is more than or equal to 140W/cm2；
Step 2, weighing the raw and auxiliary materials subjected to the bag-removing and sterilizing treatment in the step 1, weighing the raw and auxiliary materials according to the proportion of the formula of the product, and sieving the raw and auxiliary materials;
step 3, selecting the raw and auxiliary materials weighed in the step 2, selecting low-load polysaccharide dietary fibers, vitamin compositions, mineral compositions, hypoglycemic functional compositions and bifidobacterium animalis Bb-12 which are less than 8Kg for on-line premixing, and strictly mixing and amplifying the raw and auxiliary materials in a mixer according to grades to uniformly mix the raw and auxiliary materials;
the premixing condition is as follows: the mixing time is 240s, and the premixing pressure is 0.3 MPa;
step 4, taking the auxiliary materials subjected to pre-mixing and amplification in the step 3 and all raw auxiliary materials such as milk-based powder and the like to perform feeding and dry mixing;
dry mixing conditions: dry mixing time 320 s;
and 5, taking the mixed product in the step 4 for metal detection, and removing the diameters of foreign matters such as metal particles and the like: iron is more than or equal to 1.5mm, nonferrous is more than or equal to 2.0mm, and stainless steel is more than or equal to 2.0 mm.
Example 2:
the middle-aged and elderly modified milk powder for assisting in reducing blood glucose and lowering blood glucose load in the embodiment is prepared from the following raw materials in parts by weight:
830.23 parts of blended milk base powder, 140 parts of low-load polysaccharide dietary fiber, 3.25 parts of vitamin composition, 20.5 parts of mineral composition, 6 parts of hypoglycemic functional composition and 120.02 parts of bifidobacterium animalis Bb.
Wherein the blended milk base powder comprises 27% of skimmed milk powder, 20% of concentrated whey protein powder and 53% of high oil whey powder, which are 100% in total;
the low-load polysaccharide dietary fiber comprises 68% of isomaltooligosaccharide, 14% of isomaltitol, 7% of L-arabinose and 11% of inulin, and the total amount is 100%;
the vitamin composition comprises 0.51% of vitamin A, 0.008125% of vitamin D, 18.2% of vitamin E and 33.00% of vitamin C, wherein 51.72% and 48.28% of the vitamin composition are maltodextrin as auxiliary materials;
the mineral composition comprises 33.33% of calcium carbonate, 0.53% of ferrous sulfate, 0.33% of zinc sulfate, 1.04% of sodium selenite, 35.23% in total, and 64.77% of maltodextrin as an auxiliary material;
the blood sugar reducing functional composition comprises 33.3% of wheat oligopeptide, 33.3% of moringa oleifera leaf powder, 16.7% of yam powder and 16.7% of mulberry leaf extract, wherein the total content is 100%.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting blood sugar reduction in the embodiment is the same as that of the embodiment 1.
Example 3:
the middle-aged and elderly modified milk powder for assisting in reducing blood glucose and lowering blood glucose load in the embodiment is prepared from the following raw materials in parts by weight:
802.98 parts of blended milk base powder, 165 parts of low-load polysaccharide dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 9 parts of hypoglycemic functional composition and 120.02 parts of bifidobacterium animalis Bb.
Wherein the blended milk base powder comprises 28% of skimmed milk powder, 21% of concentrated whey protein powder and 51% of high oil whey powder, which account for 100%;
the low-load polysaccharide dietary fiber comprises 61% of isomaltooligosaccharide, 18% of isomaltitol, 6% of L-arabinose and 15% of resistant dextrin, and the total amount is 100%;
the vitamin composition comprises 0.47% of vitamin A, 0.0075% of vitamin D, 16.8% of vitamin E and 30.47% of vitamin C, wherein the total content is 47.75%, and 52.25% of maltodextrin is used as an auxiliary material;
the mineral composition comprises 34.00 percent of calcium carbonate, 0.54 percent of ferrous sulfate, 0.34 percent of zinc sulfate, 1.05 percent of sodium selenite, 35.93 percent of the total weight, and 64.07 percent of maltodextrin serving as an auxiliary material;
the blood sugar reducing functional composition comprises 44.4% of wheat oligopeptide, 22.2% of moringa oleifera leaf powder, 22.2% of yam powder and 11.2% of mulberry leaf extract, wherein the total content is 100%.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting blood sugar reduction in the embodiment is the same as that of the embodiment 1.
Example 4:
the middle-aged and elderly modified milk powder for assisting in reducing blood glucose and lowering blood glucose load in the embodiment is prepared from the following raw materials in parts by weight:
775.72 parts of blended milk base powder, 190 parts of low-load polysaccharide dietary fiber, 2.75 parts of a vitamin composition, 19.5 parts of a mineral composition, 12 parts of a blood sugar-reducing functional composition and 12 parts of bifidobacterium animalis Bb-120.03 parts.
Wherein the blended milk base powder comprises 32% of skimmed milk powder, 20% of concentrated whey protein powder and 48% of high oil whey powder, which are 100% in total;
the low-load polysaccharide dietary fiber comprises 53 percent of isomaltose hypgather, 24 percent of isomaltitol, 10 percent of L-arabinose and 13 percent of inulin, which account for 100 percent;
the vitamin composition comprises 0.43 percent of vitamin A, 0.006875 percent of vitamin D, 15.4 percent of vitamin E and 27.93 percent of vitamin C, wherein the total amount is 43.77 percent, and 56.23 percent is maltodextrin as an auxiliary material;
the mineral composition comprises 33.84% of calcium carbonate, 0.56% of ferrous sulfate, 0.35% of zinc sulfate, 1.09% of sodium selenite, 35.84% in total, and 64.16% of maltodextrin as an auxiliary material;
the blood sugar reducing functional composition comprises 50.0% of wheat oligopeptide, 16.7% of moringa oleifera leaf powder, 16.7% of yam powder and 16.6% of mulberry leaf extract, and the total content is 100%.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting blood sugar reduction in the embodiment is the same as that of the embodiment 1.
Example 5:
the middle-aged and elderly modified milk powder for assisting in reducing blood glucose and lowering blood glucose load in the embodiment is prepared from the following raw materials in parts by weight:
748.46 parts of blended milk base powder, 215 parts of low-load polysaccharide dietary fiber, 2.5 parts of vitamin composition, 19 parts of mineral composition, 15 parts of hypoglycemic functional composition and Bb-120.04 parts of animal bifidobacteria.
Wherein the blended milk base powder comprises 33% of skimmed milk powder, 20% of concentrated whey protein powder and 47% of high oil whey powder, which are 100% in total;
the low-load polysaccharide dietary fiber comprises 51% of isomaltooligosaccharide, 23% of isomaltitol, 12% of L-arabinose and 14% of resistant dextrin, and the total amount is 100%;
the vitamin composition comprises 0.39% of vitamin A, 0.00625% of vitamin D, 14.0% of vitamin E and 25.39% of vitamin C, wherein 39.79% in total and 60.21% of maltodextrin is used as an auxiliary material;
the mineral composition comprises 33.68% of calcium carbonate, 0.58% of ferrous sulfate, 0.36% of zinc sulfate, 1.12% of sodium selenite, 35.74% in total, and 64.26% of maltodextrin as an auxiliary material;
the blood sugar reducing functional composition comprises 46.7% of wheat oligopeptide, 20.0% of moringa oleifera leaf powder, 20.0% of yam powder and 13.3% of mulberry leaf extract, wherein the total content is 100%.
The preparation method of the modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting blood sugar reduction in the embodiment is the same as that of the embodiment 1.
Comparative example 1:
the middle-aged and old modified milk powder for assisting hypoglycemic load for reducing blood sugar in the comparative example is prepared from the following raw materials in parts by weight:
967.98 parts of blended milk base powder, 0 part of low-load polysaccharide dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 9 parts of hypoglycemic functional composition and 120.02 parts of bifidobacterium animalis Bb.
Wherein the blended milk base powder comprises 23% of skimmed milk powder, 17% of concentrated whey protein powder and 60% of high oil whey powder, and the total amount is 100%;
the vitamin composition comprises 0.47% of vitamin A, 0.0075% of vitamin D, 16.8% of vitamin E and 30.47% of vitamin C, wherein the total content is 47.75%, and 52.25% of maltodextrin is used as an auxiliary material;
the mineral composition comprises 34.00 percent of calcium carbonate, 0.54 percent of ferrous sulfate, 0.34 percent of zinc sulfate, 1.05 percent of sodium selenite, 35.93 percent of the total weight, and 64.07 percent of maltodextrin serving as an auxiliary material;
the blood sugar reducing functional composition comprises 44.4% of wheat oligopeptide, 22.2% of moringa oleifera leaf powder, 22.2% of yam powder and 11.2% of mulberry leaf extract, wherein the total content is 100%.
The preparation method of the middle-aged and elderly modified milk powder for assisting hypoglycemic load of reducing blood sugar of the comparative example is the same as that of example 1.
Comparative example 2:
the middle-aged and old modified milk powder for assisting hypoglycemic load for reducing blood sugar in the comparative example is prepared from the following raw materials in parts by weight:
976.98 parts of blended milk base powder, 0 part of low-load polysaccharide dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 0 part of hypoglycemic functional composition and 120.02 parts of bifidobacterium animalis Bb.
Wherein the blended milk base powder comprises 23% of skimmed milk powder, 17% of concentrated whey protein powder and 60% of high oil whey powder, and the total amount is 100%;
the vitamin composition comprises 0.47% of vitamin A, 0.0075% of vitamin D, 16.8% of vitamin E and 30.47% of vitamin C, wherein the total content is 47.75%, and 52.25% of maltodextrin is used as an auxiliary material;
the mineral composition comprises 34.00% of calcium carbonate, 0.54% of ferrous sulfate, 0.34% of zinc sulfate, 1.05% of sodium selenite, 35.93% in total, and 64.07% of maltodextrin as an auxiliary material.
The preparation method of the middle-aged and elderly modified milk powder for assisting hypoglycemic load of reducing blood sugar of the comparative example is the same as that of example 1.
Comparative example 3:
the middle-aged and old modified milk powder for assisting hypoglycemic load for reducing blood sugar in the comparative example is prepared from the following raw materials in parts by weight:
811.98 parts of blended milk base powder, 165 parts of low-load polysaccharide dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 0 part of hypoglycemic functional composition and 120.02 parts of bifidobacterium animalis Bb.
Wherein the blended milk base powder comprises 27% of skimmed milk powder, 22% of concentrated whey protein powder and 51% of high oil whey powder, which account for 100%;
the low-load polysaccharide dietary fiber comprises 61% of isomaltooligosaccharide, 18% of isomaltitol, 6% of L-arabinose and 15% of resistant dextrin, and the total amount is 100%;
the vitamin composition comprises 0.47% of vitamin A, 0.0075% of vitamin D, 16.8% of vitamin E and 30.47% of vitamin C, wherein the total content is 47.75%, and 52.25% of maltodextrin is used as an auxiliary material;
the mineral composition comprises 34.00% of calcium carbonate, 0.54% of ferrous sulfate, 0.34% of zinc sulfate, 1.05% of sodium selenite, 35.93% in total, and 64.07% of maltodextrin as an auxiliary material.
The preparation method of the middle-aged and elderly modified milk powder for assisting hypoglycemic load of reducing blood sugar of the comparative example is the same as that of example 1.
Measurement and characterization:
(first) evaluation of nutrient composition
The physicochemical indexes such as nutritional ingredients of the modified milk powder for middle-aged and elderly people with low blood sugar load for assisting blood sugar reduction in examples 1 to 5 and comparative examples 1 to 3 were measured.
The following experiments were repeated 3 times to ensure the accuracy of the experimental values, the data are expressed as mean ± standard deviation, and the determination results are shown in table 1:
TABLE 1 nutrient composition Table
As can be seen from Table 1, the content of each nutrient in the examples 1 to 5 and the comparative examples 1 to 3 meets the requirements of the recommended intake of each nutrient in the dietary guidelines of Chinese residents and the use standards of the food nutrition enhancer in the national standard of GB 14880-2012 food safety. Wherein, the protein content of each example and the comparative example is more than 17.3g/100g, and the content of the four nutrients of calcium, iron, zinc and selenium is not obviously different (p is more than 0.05); comparative examples 1-5 vitamin content showed a tendency to decrease with decreasing vitamin composition dosage. As can be seen from comparative examples 1 and 2, the absence of dietary fiber affects the protein, fat and carbohydrate content, resulting in a significant increase in the three nutrients (p < 0.05), and depending on the individual constitution, too much nutrient content or too much intake may cause extra nutrient burden to the body.
Compared with certain commercially available milk powder, the dry process adopted by the invention greatly reserves the nutrient components of the milk powder, has higher content of each nutrient and can well supplement nutrient elements required by human bodies.
(II) evaluation of Glycemic Index (GI) and Glycemic Load (GL) Effect
The auxiliary hypoglycemic low blood glucose load middle and old aged modified milk powders of example 3, comparative example 1, comparative example 2 and comparative example 3 were subjected to a glycemic index and glycemic load effect test to determine the effect of the addition of the low load polysaccharide dietary fiber and the hypoglycemic functional composition on the glycemic index and the glycemic load value.
The test method comprises the following steps: in the experiment, 48 middle-aged and old-aged subjects of 30-60 years are recruited, and the male and female are required to have normal body mass index, no diabetes history, no hypoglycemia symptom and tolerance of at least 10h fasting state. Meals were arranged uniformly 2 days before the trial to avoid ingestion of high dietary fiber and high sugar foods, 20 days before the trial: 00 fasting was started, the day of the assay was to avoid strenuous exercise, and the test drink test was started after the subject was sitting still for 10 min. 2 times of fasting blood samples are collected at an interval of 5min after sitting statically, capillary blood at the finger tip is taken as the blood sample part, and the blood sugar is measured by adopting a glucose oxidase method. After the fasting plasma test was completed, the reference glucose and the test milk powder (example 3, comparative example 1, comparative example 2, and comparative example 3) were orally administered, respectively, and after completion of the administration within 5min, the first oral administration time was recorded, followed by 15, 30, 45, 60, 90, and 120min for collecting blood from capillary blood in the fingertips, and the blood glucose level was measured. Wherein, each person needs to complete 2 drinking determinations of reference glucose and 1 tested milk powder respectively to be included in the calculation of GI and GL values, and the interval of each single drinking determination is 2 days.
1. Glycemic Index (GI)
GI values are used to measure the effect of carbohydrates in food intake in humans on blood glucose concentration. According to the calculation formula of GI value in WS/T652-2019 food blood glucose production index determination method, the available carbohydrate of glucose, tested milk powder, namely example 3, tested milk powder, namely comparative example 1, tested milk powder, namely comparative example 2, tested milk powder, namely comparative example 3, is 100g/100g, 55.7g/100g, 59.3g/100g and 55.7g/100g respectively, namely the drinking amount is 25.0g, 44.9g, 42.2g and 44.9g respectively, and the water is mixed with 250mL of warm water. GI value calculation reference formula (1):
2. blood Glucose Load (GL)
GL is the product of the amount of carbohydrate available in 100g of the food tested (g) and the GI value/100. Calculation of GL values reference equation (2):
according to the blood glucose measurement method, glucose is used as a reference value, and each subject is measured at 0, 15, 30, 45, 60, 90 and 120min respectively, and then the mean value is taken to draw a blood glucose concentration change curve as shown in fig. 1. As can be seen from the graph 1, after the glucose and the tested milk powder are ingested, the blood sugar value shows the trend of rising first and then falling, and reaches the highest value in 30min, so that the blood sugar value is the normal blood sugar change of healthy people, and the test data is reliable. Wherein, the blood sugar value is 9.75 plus or minus 0.17mmol/L at 30min after 10 percent of anhydrous glucose solution is taken in the fasting state, the blood sugar value is 6.025 plus or minus 0.19mmol/L after the tested milk powder is taken in example 3, and the blood sugar maximum value is reduced by 38.2 percent. Compared with the tested milk powder, namely example 3, the highest value of blood sugar is increased by 20.3 percent without adding low-load polysaccharide dietary fiber in the comparative example 1; in the comparative example 2, the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition are not added, and the maximum value of blood sugar is increased by 33.2 percent; in comparative example 3, the blood sugar maximum value is increased by 10.8% without adding the blood sugar-reducing functional composition. Therefore, the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition play a main role in the change rate of blood sugar, the blood sugar reducing capability of the low-load polysaccharide dietary fiber is better than that of the blood sugar reducing functional composition in a short time, and the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition play a dual gain role in reducing the blood sugar generation value in the presence of both the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition and are synergistic with each other.
The blood glucose generation index can be obtained by calculating the area under the blood glucose curve after drinking for 2h by using the blood glucose concentration change curve after drinking in the figure 1, and the blood glucose load can be calculated. Results of the calculations glycemic index and glycemic load values are shown in Table 2, and judged on a food GI value and GL value scale (GI < 55 for low GI foods, 55 < GI < 70 for medium GI foods, GI > 70 for high GI foods, GL < 10 for low GL foods, 10 < GL < 20 for medium GL foods, GL > 20 for high GL foods), the milk powder tested-low GI, low GL foods in example 3, low GI, medium GL foods in comparative example 1, medium GI, medium GL foods in comparative example 2, and low GI, low GL foods in comparative example 3. Compared with the food grading judgment of the tested milk powder, the food grading judgment of the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition in the example 3 can obviously (p is less than 0.05) reduce GI (glycemic index) and GL (glycemic index) values, so that the blood sugar generating capacity of the food grading judgment is obviously reduced. The GI and GL values of comparative example 1, comparative example 2 and comparative example 3 further prove that the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition are synergistic with each other and have the effect of reducing the blood sugar load.
TABLE 2 glycemic index and glycemic load assessment
Note: different superscript letters indicate significant differences in GI and GL values for different groups (p < 0.05)
(III) evaluation of stability of auxiliary hypoglycemic agent
A trial drink test of the auxiliary blood sugar reducing stability effect is carried out on the auxiliary blood sugar reducing low blood sugar load middle-aged and old modified milk powder of the examples 1 to 5 and the comparative examples 1 to 3, so as to judge the influence of the contents of the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition on the auxiliary blood sugar reducing stability.
The test method comprises the following steps: in the experiment, 80 middle-aged and old-aged subjects of 30-70 years old are recruited in public, and half of men and women are required to suffer from mild and moderate diabetes, the fasting blood glucose is 8.0-9.5 mmol/L, and the subjects participate in the experiment voluntarily. The subjects are randomly divided into 8 groups, each group of the subjects is half of a male and a female, the subjects drink the milk for 30 days, the middle-aged and the elderly are brewed with 180mL of warm water to regulate 32g of corresponding blood sugar load for assisting in reducing the blood sugar before breakfast and dinner every day, the milk is required to be half of medicine, light in diet and rich in nutrition, the blood sugar of fasting, before dinner and after dinner is measured every 15 days, and the blood sugar is detected by adopting a glucose oxidase method.
The blood glucose measurements were repeated 3 times to ensure the accuracy of the experimental values, and the data are expressed as the mean ± standard deviation of blood glucose for each subject. Experimental analysis significant analysis was performed using IBM SPSS Statistics 20 software, and the results are shown in table 3.
As can be seen from Table 3, the blood glucose levels of the patients with mild and moderate diabetes can be reduced in examples 1-5, and the blood glucose levels are significantly reduced (p < 0.05) with the increase of the contents of the dietary fiber with low load polysaccharide and the blood glucose-reducing functional composition, wherein the fasting blood glucose level in example 5 can be reduced by 11.4% at most, and the blood glucose level in example 4 can be reduced by 10.0% at most 1h after a meal. After the administration is halved, the middle-aged and old modified milk powder with the hypoglycemic load for assisting in reducing the blood sugar plays an auxiliary role in reducing the blood sugar value, and the addition amount of the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition influences the blood sugar reducing effect, namely the blood sugar reducing degree is increased along with the increase of the contents of the low-load polysaccharide dietary fiber and the blood sugar reducing functional composition.
TABLE 3 Effect of Low-load polysaccharide dietary fiber and hypoglycemic functional composition addition on auxiliary hypoglycemic stability
Note: different superscript letters indicate that the blood sugar values of the same group at different drinking times have significant difference (p < 0.05)
Claims (10)
1. The middle-aged and old modified milk powder for assisting in reducing blood sugar and blood sugar load is characterized by comprising the following raw materials in parts by weight: 748-858 parts of blended milk base powder, 115-215 parts of low-load polysaccharide dietary fiber, 2.5-3.5 parts of a vitamin composition, 19-21 parts of a mineral composition, 3-15 parts of a blood sugar reducing functional composition and 0.04 part of bifidobacterium animalis Bb-120.01.
2. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in reducing blood sugar as claimed in claim 1, wherein the protein content of the milk powder is not less than 17.3g/100g, the fat content is not less than 9.0g/100g, the vitamin A content is 300-900 μ g/100g, the vitamin D content is 6.3-12.5 μ g/100g, the vitamin E content is 10-31 mg/100g, and the vitamin C content is 30-100 mg/100 g.
3. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in reducing blood sugar as claimed in claim 1, wherein the calcium content of the milk powder is not higher than 1200mg/100g, the iron content is 6-20 mg/100g, the zinc content is 3-6 mg/100g, and the selenium content is 14-28 mg/100 g.
4. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in lowering blood sugar as claimed in claim 1, wherein the content of Bifidobacterium animalis Bb-12 in the milk powder is not less than 8 x 106CFU/g。
5. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in reducing blood sugar as claimed in claim 1, wherein the modified milk base powder is one or more of skimmed milk powder, concentrated whey protein powder, and high oil whey powder, and is mixed at any ratio.
6. The middle-aged and elderly modified milk powder with low blood sugar load for assisting blood sugar reduction according to claim 1, wherein the low-load polysaccharide dietary fiber is one or more of isomaltooligosaccharide, isomaltitol, L-arabinose, inulin, and resistant dextrin, and is mixed according to any ratio.
7. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in lowering blood sugar of claim 1, wherein the vitamin composition is one or more of retinyl acetate, cholecalciferol, dl-alpha-tocopherol acetate, and sodium L-ascorbate, which are mixed according to a certain ratio.
8. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in lowering blood sugar as claimed in claim 1, wherein the mineral composition is one or more of calcium carbonate, ferrous sulfate, zinc sulfate, and sodium selenite, and is mixed at a certain ratio.
9. The modified milk powder for middle-aged and elderly people with hypoglycemic load for assisting in reducing blood sugar as claimed in claim 1, wherein the hypoglycemic functional composition is one or more of wheat oligopeptide, moringa leaf powder, yam powder and mulberry leaf extract, and is mixed according to any proportion.
10. A method for preparing a hypoglycemic load middle-aged and elderly modified milk powder for assisting in lowering blood glucose according to claim 1, comprising the steps of:
step 1, mixing raw and auxiliary materials with milk base powder, low-load polysaccharide dietary fiber, a vitamin composition, a mineral composition, a blood sugar-reducing functional composition and an animal bifidobacterium Bb-12, carrying out air shower dedusting sterilization, and removing an outer package after sterilization;
and (3) sterilization treatment conditions: the air shower and sterilization time is 90 s; ultraviolet intensity is more than or equal to 140 mu W/cm2；
Step 2, weighing the raw and auxiliary materials subjected to the bag-removing and sterilizing treatment in the step 1, weighing the raw and auxiliary materials according to the proportion of the formula of the product, and sieving the raw and auxiliary materials;
step 3, carrying out on-line premixing on the raw and auxiliary materials processed in the step 2;
the premixing condition is as follows: the mixing time is 240s, and the premixing pressure is 0.20-0.4 MPa;
step 4, dry mixing the premix obtained in the step 3 to obtain a finished product;
dry mixing conditions: dry mixing time 320 s;
step 5, taking a finished product for metal detection;
removing the diameter of foreign matters: iron is more than or equal to 1.5mm, nonferrous is more than or equal to 2.0mm, and stainless steel is more than or equal to 2.0 mm.
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