CN113509992B

CN113509992B - Bead type homogenizer for grinding biological material

Info

Publication number: CN113509992B
Application number: CN202110332659.7A
Authority: CN
Inventors: 冯国祯
Original assignee: Territory Animal Diagnosis And Treatment Technology Xiamen Co ltd
Current assignee: Territory Animal Diagnosis And Treatment Technology Xiamen Co ltd
Priority date: 2021-03-29
Filing date: 2021-03-29
Publication date: 2022-08-16
Anticipated expiration: 2041-03-29
Also published as: CN113509992A

Abstract

The invention relates to the technical field of grinding, and discloses a bead type homogenizer for grinding biological materials, which comprises a box body, wherein a seat plate is arranged in the box body, a bead driving pipe is sleeved in the middle of the seat plate, a grinding pipe is arranged above the seat plate, a sealing plug is clamped in the grinding pipe, and a bead circulating pipe is connected between the grinding pipe and the bead driving pipe. According to the grinding tube, the air nozzle at the bottom of the bead driving tube provides upward power for the grinding beads, the rotation of the rotating wheel is matched, and the relative positions of the air nozzle and the grinding beads are arranged, so that a rotating force is provided for the grinding beads entering the grinding tube, the shearing and grinding effects on materials in the rotation process of the grinding beads are improved, the purpose of setting the running track of the grinding beads is achieved by utilizing the wind power of the air nozzle and the attraction of the magnetic strip, the problem that the grinding beads are collided with the grinding tube to cause breakage of the grinding tube due to traditional three-dimensional shaking of the grinding tube is solved, and the service life of the grinding tube is prolonged.

Description

Bead type homogenizer for grinding biological material

Technical Field

The invention relates to the technical field of grinding, in particular to a bead type homogenizer for grinding biological materials.

Background

The biological sample homogenizer is a fast high-flux homogenizer and integrates three functions of grinding, cracking and homogenizing. The method achieves the purposes of grinding, cracking and homogenizing a sample by beating grinding beads (glass beads, ceramic beads, steel balls and the like) through three-dimensional high-speed vibration. Can effectively homogenize samples of animal and plant tissues, bacteria, fungi and the like.

In the vibration process of the existing bead type homogenizer, grinding beads move irregularly, the grinding effect on materials is achieved through collision and shearing force between the beads, but the grinding beads continuously impact a sample tube when moving at a high speed, the sample tube is easily damaged, the grinding beads are easily abraded or broken due to impact between the grinding beads and the sample tube, abrasion residues of the grinding beads are mixed with a sample, and the accuracy of sample detection is reduced; and after the grinding beads are worn, the situation that the beads are ground by large beads is generated along with the lengthening of the grinding time, and the deformation and the breakage of the beads are accelerated.

Disclosure of Invention

Aiming at the defects of the prior bead type homogenizer in the use process, the invention provides the bead type homogenizer for grinding the biological material, which has the advantages of collecting broken grinding beads and reducing the breakage of the grinding beads and solves the problems in the prior art.

The invention provides the following technical scheme: the utility model provides a biomaterial grinds and uses pearl formula homogeneity appearance, the power distribution box comprises a box body, the inside of box is equipped with the bedplate, the pearl driving tube has been cup jointed at the middle part of bedplate, the grinding tube has been placed to the top of bedplate, the inside joint of grinding tube has the sealing plug, be connected with the pearl circulating pipe between grinding tube and the pearl driving tube, be equipped with the equal trachea that is located the bedplate below in the inner chamber of box, fixed mounting has the air nozzle on the equal trachea, the fixed bottom of cup jointing at the pearl driving tube of the end of giving vent to anger of air nozzle, equal trachea connection has the air pump.

Preferably, the top of pearl driving tube has been seted up and has been spouted the pearl mouth, the inside of pearl driving tube is equipped with the swiveling wheel, the top surface of pearl driving tube is equipped with the stopper, the internal diameter of pearl driving tube is the same with the diameter of grinding the pearl, the lower extreme at the pearl driving tube is connected to the pearl circulating pipe.

Preferably, one the grinding pipe is connected with two pearl driving tubes, two the pearl driving tube sets up along the axis symmetry of grinding the pipe, two the direction of rotation of interior swiveling wheel of pearl driving tube is the same, two the air nozzle of pearl driving tube lower extreme deviates in the same one side of spouting pearl mouth axis respectively.

Preferably, the bead inlet that link up is seted up to the bottom surface of grinding pipe, be equipped with protruding type rubber circle on the inner wall of bead inlet, the bead outlet has all been seted up to the lateral wall of the symmetry of grinding pipe upper end, the inner wall of bead outlet is equipped with concave type rubber circle, be equipped with the draw-in groove that is located bead outlet both sides on the inner wall of grinding pipe, the bottom surface outer wall of grinding pipe seted up with stopper assorted spacing groove.

Preferably, the inside of sealing plug is equipped with the filter plate, the bar is led to the groove has been seted up to the lateral wall of sealing plug, be connected with the magnetic stripe that is located the bar and leads to the groove middle part on the sealing plug, the inside of sealing plug is equipped with the magnetic sheet that is located the filter plate top, the top of magnetic sheet has the coil around, magnetic stripe and draw-in groove phase-match.

Preferably, the sealing plug includes filter screen and solid sideboard, the filter screen is located the periphery of solid sideboard, filter plate and sealing plug demountable installation.

Preferably, the convex rubber ring and the concave rubber ring have the same structure, the convex rubber ring is in a conical shape, through holes are formed in both ends of the convex rubber ring, and the inner diameter of the conical top end of the convex rubber ring is slightly smaller than the diameter of the grinding bead.

The invention has the following beneficial effects:

1. according to the grinding tube, the air nozzle at the bottom of the bead driving tube provides upward power for the grinding beads, the rotation of the rotating wheel is matched, and the relative positions of the air nozzle and the grinding beads are arranged, so that a rotating force is provided for the grinding beads entering the grinding tube, the shearing and grinding effects on materials in the rotation process of the grinding beads are improved, the purpose of setting the running track of the grinding beads is achieved by utilizing the wind power of the air nozzle and the attraction of the magnetic strip, the problem that the grinding beads are collided with the grinding tube to cause breakage of the grinding tube due to traditional three-dimensional shaking of the grinding tube is solved, and the service life of the grinding tube is prolonged.

2. The air nozzle and the rotating wheel are used for providing higher rotating force for the grinding balls, and the closer distance between the two ball driving pipes is set, so that the distance between the grinding balls with the opposite rotating directions of the two contact surfaces is shortened, the materials clamped between the two grinding balls in the middle grinding area are subjected to shearing and friction acting forces, the purpose of crushing the materials is achieved, the traditional impact grinding mode is replaced by a grinding mode of rolling, shearing and friction, the grinding effect is guaranteed, and the grinding probability of the grinding balls is reduced.

3. According to the invention, through the attraction of the magnetic strips, the magnetic plate and the coils to the grinding ball fragments and the filtering action of the filter plate on the grinding balls, the grinding ball fragments can be adsorbed through the filter plate, so that the crushed grinding balls are separated, the impurities in the materials are reduced, the phenomenon of mixing large and small grinding balls is avoided, and the service life of the grinding balls is prolonged.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of the structure of the bead driving tube of the present invention;

FIG. 3 is a schematic top view of the polishing tube of the present invention;

FIG. 4 is a partial cross-sectional view of the abrasive tube of the present invention;

fig. 5 is a schematic view of the sealing plug of the present invention;

fig. 6 is a top view of a filter plate of the present invention;

fig. 7 is a front view of the grinding tube of the present invention.

In the figure: 1. a box body; 2. a seat plate; 3. a bead driving tube; 301. spraying a bead opening; 302. a rotating wheel; 303. a limiting block; 4. grinding the tube; 401. a bead inlet; 402. a limiting groove; 403. a bead outlet; 404. a convex rubber ring; 405. a concave rubber ring; 406. a card slot; 5. a sealing plug; 501. filtering the plate; 5010. filtering with a screen; 5011. a solid sideboard; 502. a magnetic strip; 503. a magnetic plate; 504. a coil; 505. a strip-shaped through groove; 6. a bead circulation tube; 7. a gas homogenizing pipe; 8. an air nozzle; 9. an air pump.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-7, a bead type homogenizer for grinding biological materials, comprising a box body 1, a seat plate 2 is arranged inside the box body 1, a bead driving tube 3 is sleeved at the middle part of the seat plate 2, a grinding tube 4 is placed above the seat plate 2, a sealing plug 5 is clamped inside the grinding tube 4, a bead circulating tube 6 is connected between the grinding tube 4 and the bead driving tube 3, an air equalizing tube 7 positioned below the seat plate 2 is arranged in the inner cavity of the box body 1, an air nozzle 8 is fixedly installed on the air equalizing tube 7, the air outlet end of the air nozzle 8 is fixedly sleeved at the bottom of the bead driving tube 3, the air equalizing tube 7 is connected with an air pump 9, in view of the fact that some materials cannot contact with air during grinding and are prevented from reacting with some substances in the air, a sterilizing device can be connected between the air pump 9 and the air equalizing tube 7, after the air is sterilized and disinfected, the air is conveyed into the air equalizing tube 7, and then sterile air enters the inner cavity of the bead driving tube 3 through the air nozzle 8, the grinding beads in the bead driving tube 3 are blown upwards and enter the grinding tube 4, the materials are crushed through the collision and shearing with the materials in the grinding tube 4, then the grinding beads reenter the bead driving tube 3 through the bead circulating tube 6, and the circulation is repeated.

The top of the bead driving tube 3 is provided with a bead spraying opening 301, grinding beads fly out of the bead spraying opening 301 and then enter the grinding tube 4, a rotating wheel 302 is arranged inside the bead driving tube 3, the top surface of the bead driving tube 3 is provided with a limiting block 303, the inner diameter of the bead driving tube 3 is the same as the diameter of the grinding beads, and the bead circulating tube 6 is connected to the lower end of the bead driving tube 3; one grinding tube 4 is connected with two bead driving tubes 3, the two bead driving tubes 3 are symmetrically arranged along the central axis of the grinding tube 4, the rotating directions of the rotating wheels 302 in the two bead driving tubes 3 are the same, the air nozzles 8 at the lower ends of the two bead driving tubes 3 are respectively deviated from the same side of the central axis of the bead spraying port 301, and the distance between the other two bead driving tubes 3 is smaller or contacted, so that the distance between the grinding beads entering the grinding tube 4 from the bead driving tubes 3 is smaller, referring to the attached drawings 1 and 2, because the rotating directions of the two rotating wheels 302 are the same, and the two rotating wheels 302 are positioned at two sides of the moving track of the grinding beads in the bead driving tubes 3, the rotating directions of the grinding beads in the left bead driving tube 3 are opposite to the rotating directions of the sides where the grinding beads in the right bead driving tube 3 are close enough, when the two bead driving tubes 3 are close enough, the gaps between the grinding beads entering the grinding tube 4 from the bead driving tubes 3 and communicated in the rotating directions are smaller, the material between the two grinding beads is sheared and rubbed, so that the crushing of the material is accelerated, and the air flow of the two air nozzles 8 connected with the two bead driving pipes 3 can improve the rotation of the grinding beads and provide power for the upward movement of the grinding beads.

The bottom surface of the grinding pipe 4 is provided with a bead inlet 401 which is through, the bead spraying port 301 is communicated with the bead inlet 401, so that grinding beads can move from the bead driving pipe 3 to the inside of the grinding pipe 4, the inner wall of the bead inlet 401 is provided with a convex rubber ring 404, when the grinding beads move from the bead driving pipe 3 to the grinding pipe 4, the top end of the convex rubber ring 404 needs to be opened, when the acting force of the grinding beads does not exist, the top end of the convex rubber ring 404 is basically in a closed state, so that the large amount of materials in the grinding pipe 4 can be prevented from flowing back to the bead driving pipe 3, the symmetrical side walls at the upper end of the grinding pipe 4 of the convex rubber ring 404 are provided with bead outlets 403 which are communicated with the bead circulating pipe 6 and used for sending the grinding beads in the grinding pipe 4 back to the bead driving pipe 3, the inner wall of the bead outlets 403 is provided with a concave rubber ring 405, the concave rubber ring 405 is used for applying a certain pressure to the grinding beads, so that the grinding beads are subjected to resistance when entering the bead circulating pipe 6, and the grinding beads to be blocked at the concave rubber ring 405 are subjected to the impact force of the grinding beads newly ejected from the rear part, so that the resistance of the concave rubber ring 405 can be overcome and the grinding beads can enter the bead circulating pipe 6, so that impact force exists between the grinding beads, the material crushing is promoted, and because the impact force between the grinding beads in the above mode is limited, the material crushing can be achieved, the grinding beads can be prevented from being crushed, the problem of grinding bead crushing caused by irregular collision between the grinding beads in the traditional grinding process is avoided, the inner wall of the grinding pipe 4 is provided with clamping grooves 406 at two sides of a bead outlet 403, the outer wall of the bottom surface of the grinding pipe 4 is provided with limiting grooves 402 matched with the limiting blocks 303, namely after the materials are put into the grinding pipe 4, the limiting grooves 402 at the bottom of the grinding pipe 4 are clamped with the limiting blocks 303, and the bead outlet 403 is also clamped with the bead circulating pipe 6 at this time, the bead circulating pipe 6 is fixed, referring to fig. 1, a seat block for separating two adjacent grinding pipes 4 is arranged above the seat plate 2, and the bead circulating pipe 6 is fixed inside the seat block, so that the grinding pipes 4 can be conveniently taken out and the materials in the grinding pipes 4 can be conveniently extracted by the limiting clamping manner.

A filter plate 501 is arranged in the sealing plug 5, the filter plate 501 is used for separating broken grinding balls from complete grinding balls, a strip-shaped through groove 505 is formed in the side wall of the sealing plug 5, a magnetic strip 502 located in the middle of the strip-shaped through groove 505 is connected to the sealing plug 5, the magnetic strip 502 is matched with a clamping groove 406 on the inner wall of the grinding pipe 4, and can be clamped in the clamping groove 406, because the clamping groove 406 is located on two sides of a ball outlet 403, the magnetic strip 502 located in the clamping groove 406 has attraction towards two sides to the grinding balls running above the grinding pipe 4, so that the grinding balls move towards the ball outlet 403 and can return to the ball driving pipe 3 through a ball circulating pipe 6, a magnetic plate 503 located above the filter plate 501 is arranged in the sealing plug 5, a coil 504 is wound on the top of the magnetic plate 503, and when current is supplied to the coil 504, the coil 504 generates a magnetic field and magnetizes the magnetic plate 503, therefore, the magnetic grinding ball fragments can be attracted, so that the grinding ball fragments have the force of upwards penetrating through the filter plate 501, and the reason for using the coil 504 is that when the magnetic plate 503 loses magnetism after the current of the coil 504 is cut off, the grinding ball fragments can fall off from the magnetic plate 503, so that the grinding ball fragments can be conveniently removed.

The sealing plug 5 comprises a filter screen 5010 and a solid side plate 5011, the filter screen 5010 is located on the periphery of the solid side plate 5011, the filter plate 501 and the sealing plug 5 are detachably mounted, the sealing plug 5 with different apertures and meshes can be replaced by grinding beads with different sizes, in addition, due to the common attraction force of the magnetic strip 502 and the magnetic plate 503 on fragments, the fragments can move upwards in an inclined manner, and therefore the fragments can impact on the inner wall of the sealing plug 5 and fall on the filter screen 5010, and a part of the fragments can be attached to the magnetic plate 503 due to the attraction force of the magnetic plate 503.

The structure of the convex rubber ring 404 is the same as that of the concave rubber ring 405, the convex rubber ring 404 is in a cone shape, through holes are formed at two ends of the convex rubber ring 404, the inner diameter of the cone top end of the convex rubber ring 404 is slightly smaller than the diameter of a grinding bead, the convex rubber ring 404 is used for reducing the backflow of materials in the grinding pipe 4 to the bead driving pipe 3, so that the end with a small opening of the convex rubber ring 404 faces the inner cavity of the grinding pipe 4, the concave rubber ring 405 is used for providing certain resistance for the grinding bead and delaying the moving speed of the grinding bead to the bead circulating pipe 6, so that the grinding bead at the rear can impact the grinding bead at the front, the materials among the grinding beads are subjected to impact grinding, the grinding effect is further improved, the end with a small opening of the concave rubber ring 405 faces the outer side of the grinding pipe 4, in addition, when the grinding pipe is used, the height of the materials to be ground in the grinding pipe 4 is lower than the position of the bead outlet 403, the flow rate of the materials from the bead outlet 403 can be reduced.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a biomaterial grinds with pearl formula homogeneity appearance, includes box (1), its characterized in that: the bead grinding box is characterized in that a seat plate (2) is arranged inside the box body (1), a bead driving tube (3) is sleeved in the middle of the seat plate (2), a grinding tube (4) is placed above the seat plate (2), a sealing plug (5) is clamped inside the grinding tube (4), a bead circulating tube (6) is connected between the grinding tube (4) and the bead driving tube (3), a gas homogenizing tube (7) located below the seat plate (2) is arranged in an inner cavity of the box body (1), a gas nozzle (8) is fixedly installed on the gas homogenizing tube (7), the gas outlet end of the gas nozzle (8) is fixedly sleeved at the bottom of the bead driving tube (3), and the gas homogenizing tube (7) is connected with a gas pump (9);

the top of the bead driving tube (3) is provided with a bead spraying opening (301), a rotating wheel (302) is arranged inside the bead driving tube (3), the top surface of the bead driving tube (3) is provided with a limiting block (303), the inner diameter of the bead driving tube (3) is the same as the diameter of grinding beads, and the bead circulating tube (6) is connected to the lower end of the bead driving tube (3);

the grinding tube (4) is connected with two bead driving tubes (3), the two bead driving tubes (3) are symmetrically arranged along the central axis of the grinding tube (4), the rotating directions of the rotating wheels (302) in the two bead driving tubes (3) are the same, and the air nozzles (8) at the lower ends of the two bead driving tubes (3) are respectively deviated from the same side of the central axis of the bead spraying port (301);

the ball grinding device is characterized in that a penetrating ball inlet (401) is formed in the bottom surface of the grinding pipe (4), a convex rubber ring (404) is arranged on the inner wall of the ball inlet (401), ball outlets (403) are formed in symmetrical side walls of the upper end of the grinding pipe (4), a concave rubber ring (405) is arranged on the inner wall of each ball outlet (403), clamping grooves (406) located on two sides of each ball outlet (403) are formed in the inner wall of the grinding pipe (4), and a limiting groove (402) matched with a limiting block (303) is formed in the outer wall of the bottom surface of the grinding pipe (4);

a filter plate (501) is arranged in the sealing plug (5), a strip-shaped through groove (505) is formed in the side wall of the sealing plug (5), a magnetic strip (502) located in the middle of the strip-shaped through groove (505) is connected to the sealing plug (5), a magnetic plate (503) located above the filter plate (501) is arranged in the sealing plug (5), a coil (504) is wound on the top of the magnetic plate (503), and the magnetic strip (502) is matched with the clamping groove (406);

the sealing plug (5) comprises a filter screen (5010) and a solid side plate (5011), the filter screen (5010) is located on the periphery of the solid side plate (5011), and the filter plate (501) and the sealing plug (5) are detachably mounted.

2. The bead homogenizer for grinding biological materials, according to claim 1, wherein: the structure of the convex rubber ring (404) is the same as that of the concave rubber ring (405), the convex rubber ring (404) is in a conical shape, through holes are formed in two ends of the convex rubber ring (404), and the inner diameter of the conical top end of the convex rubber ring (404) is slightly smaller than the diameter of a grinding bead.