CN113507920A - 用于乙型肝炎病毒感染的RNAi剂 - Google Patents

用于乙型肝炎病毒感染的RNAi剂 Download PDF

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Publication number
CN113507920A
CN113507920A CN202080013136.XA CN202080013136A CN113507920A CN 113507920 A CN113507920 A CN 113507920A CN 202080013136 A CN202080013136 A CN 202080013136A CN 113507920 A CN113507920 A CN 113507920A
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Prior art keywords
seq
administered
sequence
hbv
rnai agent
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Pending
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CN202080013136.XA
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Chinese (zh)
Inventor
B·D·吉文
J·C·哈米尔顿
T·石吕普
M·G·博蒙
O·伦斯
R·C·M·卡尔梅耶
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Glaxosmithkline Intellectual Property Third Ltd
Arrowhead Pharmaceuticals Inc
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Janssen Pharmaceuticals Inc
Arrowhead Pharmaceuticals Inc
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Publication of CN113507920A publication Critical patent/CN113507920A/zh
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CN202080013136.XA 2019-02-07 2020-02-07 用于乙型肝炎病毒感染的RNAi剂 Pending CN113507920A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962802614P 2019-02-07 2019-02-07
US62/802614 2019-02-07
US201962853659P 2019-05-28 2019-05-28
US62/853659 2019-05-28
US201962932315P 2019-11-07 2019-11-07
US62/932315 2019-11-07
PCT/US2020/017264 WO2020163747A1 (en) 2019-02-07 2020-02-07 Rnai agents for hepatitis b virus infection

Publications (1)

Publication Number Publication Date
CN113507920A true CN113507920A (zh) 2021-10-15

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CN202080013136.XA Pending CN113507920A (zh) 2019-02-07 2020-02-07 用于乙型肝炎病毒感染的RNAi剂

Country Status (15)

Country Link
US (1) US20210395745A1 (https=)
EP (2) EP4707394A3 (https=)
JP (2) JP7585214B2 (https=)
KR (1) KR20210130736A (https=)
CN (1) CN113507920A (https=)
AU (1) AU2020219355A1 (https=)
BR (1) BR112021015361A2 (https=)
CA (1) CA3129261A1 (https=)
IL (1) IL285257A (https=)
JO (1) JOP20210208A1 (https=)
MX (1) MX2021009495A (https=)
PH (1) PH12021551866A1 (https=)
SG (1) SG11202108395SA (https=)
TW (1) TWI872048B (https=)
WO (1) WO2020163747A1 (https=)

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EA202091513A1 (ru) 2017-12-19 2020-09-09 Янссен Сайенсиз Айрлэнд Анлимитед Компани Вакцины против вируса гепатита b (hbv) и их применение
SG11202108395SA (en) * 2019-02-07 2021-08-30 Arrowhead Pharmaceuticals Inc Rnai agents for hepatitis b virus infection
US20210403908A1 (en) * 2020-06-22 2021-12-30 Janssen Pharmaceuticals, Inc. Compositions and methods for treatment of hepatitis d virus infection
WO2022078479A1 (en) * 2020-10-16 2022-04-21 Janssen Pharmaceuticals, Inc. Combination therapy for treating hepatitis b virus infection
TW202245809A (zh) * 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
US20240124879A1 (en) * 2020-12-18 2024-04-18 Olix Pharmaceuticals, Inc. Rnai agent for inhibiting hbv expression and use thereof
WO2022152869A1 (en) * 2021-01-15 2022-07-21 Janssen Sciences Ireland Unlimited Company Use of oligonucleotides for individuals with hepatic impairment
EP4367241A1 (en) * 2021-07-09 2024-05-15 GlaxoSmithKline Intellectual Property (No.3) Limited Use of oligonucleotides for individuals with renal impairment
WO2025199466A1 (en) 2024-03-22 2025-09-25 Purdue Research Foundation Liver-specific asialoglycoprotein receptor targeting ligands, conjugates comprising same, and related compositions and methods of use
CA3279332A1 (en) * 2024-07-08 2026-03-01 Hangzhou Tianlong Pharmaceutical Co., Ltd. DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF

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