CN113502221A

CN113502221A - Air microorganism detection robot

Info

Publication number: CN113502221A
Application number: CN202110809854.4A
Authority: CN
Inventors: 王忠堂
Original assignee: Accuragen Inc
Current assignee: Accuragen Inc
Priority date: 2021-07-17
Filing date: 2021-07-17
Publication date: 2021-10-15

Abstract

The utility model provides an air microorganism detection robot, reach preset position with the help of removing the chassis, carry out automatic continuous high-efficient seizure collection air particle with the help of artificial intelligence, the air particle of collection sends into detection analysis system through the manipulator, with the help of a plurality of intelligent detection sensors, the kind and the quantity of microorganism in the automated inspection air particle, air microorganism testing result is by air microorganism detection robot real-time dynamic release, or upload cloud ware confession remote access, thereby realize that the machine replaces the people to implement high-strength repeated air microorganism monitoring, provide specific pathogenic microorganism warning information for hospital, school or other crowd gathering places in real time.

Description

Air microorganism detection robot

Technical Field

The invention relates to an intelligent detection technology of microorganisms, in particular to an air microorganism detection robot.

Background

The core of infectious disease prevention and treatment lies in eliminating infectious sources, cutting off transmission ways and protecting susceptible people. Studies have shown that wearing a mask helps to cut off COVID-19 transmission when the air particles contain low concentrations of SARS-CoV-2, and wearing a mask does not prevent COVID-19 transmission when the air particles contain high concentrations of SARS-CoV-2. Therefore, during the time of a COVID-19 pandemic, hospitals, schools, large commercial establishments, airports or other places where people gather, it is very necessary to monitor SARS-CoV-2 in the air in real time for instructing people to take appropriate preventive measures, enhance personal protection, close suspicious places in time and perform environmental disinfection, and accurately prevent and control COVID-19.

In addition, hospitals receiving and treating COVID-19 patients and isolated hotels living with COVID-19 suspicious infected persons need to dynamically monitor SARS-CoV-2 in the ambient air in real time for guiding the timing and frequency of implementing environmental disinfection and evaluating the disinfection effect in time.

At present, an air particle collecting and capturing technology and a detection and analysis technology depend on manual operation, a detection result cannot be obtained in time, and a large amount of manpower is consumed for real-time dynamic monitoring. In addition, hospitals, isolation hotels that receive COVID-19 patients require a higher frequency of airborne particle collection and microbiological detection, which will undoubtedly increase the risk of SARS-CoV-2 exposure for the operator.

In view of this, there is a need for an airborne microbe detection robot, which can automatically and continuously capture and collect airborne particles with high efficiency, automatically detect the types and amounts of specific microbes in the airborne particles, and dynamically issue the detection results in real time, so as to replace manual implementation of high-intensity repetitive airborne microbe monitoring and guide people to take appropriate preventive measures to control respiratory infectious diseases in real time.

Disclosure of Invention

The technical problem to be solved.

An object of the application is to provide an air microorganism detection robot, air microorganism detection robot modularization configuration hardware, software, reagent and consumptive material, arrive preset position by oneself with the help of removing the chassis, start the gas circuit system by oneself, with the help of removable collection module, automatic high efficiency is caught and is gathered the air particle in succession, the air particle of collection sends into detection analysis module through the arm, with the help of a plurality of intelligent detection sensors, microorganism in the automatic detection air particle, the real-time dynamic release of air microorganism testing result, or upload cloud server and supply remote access, thereby realize that the machine substitutes people implements the iterative air microorganism monitoring of high strength, for the hospital, school or other crowds gather the place and provide specific pathogenic microorganism warning information in real time.

The second technical proposal.

In order to solve the technical problem, an aspect of the present application provides an air microorganism detection robot, and it is including removing chassis, gas circuit system, analytic system, it includes the intelligence device of moving to remove the chassis, gas circuit system includes sampling port, intelligent air pump, intelligent pneumatic valve, disinfection liquid chamber, tail gas mouth and connecting tube, analytic system includes collection module, detection module, interpretation module, report module, wherein, collection module is including compiling the box, collect box pre-installation filler, the filler includes microballon, fibre, filter membrane, detection module includes manipulator, biochemical reaction chamber, photoelectric detection room, the manipulator transports collect the box, biochemical reaction chamber includes antigen-antibody reaction subassembly sensor, gene chip sensor, temperature control device, application of sample device, elution pond, reprocessing device, The photoelectric detection room comprises a light source and a scanning recording device, the interpretation module is used for inputting scanning recording data into the central data processing unit to obtain quantitative indexes of specific microorganisms, and the report module displays on a display screen on site and uploads to a cloud server for remote access.

In an exemplary embodiment of the present application, the number of the sampling ports, the intelligent air pump, the intelligent air valve, and the collection module units is at least two, wherein one sampling port is arranged on the mechanical arm.

In an exemplary embodiment of the present application, the collection box, the filler are made of a colorless transparent material, so that the photoelectric detection is not affected, and the collection box comprises an air inlet and an air outlet.

In an exemplary embodiment of the present application, the filler is pre-coated with at least one microbial antigen and at least one chromogenic marker is correspondingly configured for analyzing at least one microbe.

In an exemplary embodiment of the present application, the microspheres include large-diameter microspheres, medium-diameter microspheres, and small-diameter microspheres, and the microspheres are classified according to the diameter of the microspheres and loaded into the collection box, wherein the large-diameter microspheres are close to the air inlet, and the small-diameter microspheres are close to the air outlet.

In an exemplary embodiment of the present application, the fibers are classified into sparse fibers and dense fibers, and the sparse fibers and the dense fibers are loaded into the collecting box according to the classification of the density of the fibers, and the sparse fibers are close to the air inlet and the dense fibers are close to the air outlet.

In an exemplary embodiment of the present application, the filter membranes are divided into a large-aperture filter membrane, a medium-aperture filter membrane, and a small-aperture filter membrane, and are classified according to the filter membrane aperture and loaded into the collection box, wherein the large-aperture filter membrane is close to the air inlet, and the small-aperture filter membrane is close to the air outlet.

In an exemplary embodiment of the present application, the number of the robot arms is at least two, so that different tasks are accomplished.

In an exemplary embodiment of the present application, the device further comprises a mechanical arm, a hose and a suction nozzle, and the mechanical arm, the hose and the suction nozzle are used for intelligently collecting air particles deposited on the surface of the article.

In an exemplary embodiment of the present application, the method further comprises a conventional culture method or an air impact method, and the total amount of airborne microorganisms and the number of live microorganisms are detected by a chemiluminescence method.

In an exemplary embodiment of the present application, the detection module includes an intelligent sensor integrated with a manipulator, a biochemical reaction chamber and a photoelectric detection chamber.

In an exemplary embodiment of the present application, an environment monitoring sensor is further included for monitoring temperature, humidity, noise, air pollution markers.

In an exemplary embodiment of the present application, a safety monitoring sensor is further included for monitoring poison gas, radiation, fire.

In an exemplary embodiment of the present application, the air sterilizer further includes an intelligent environmental sterilizing device for autonomously performing air sterilizing operation.

In one aspect of the present application, there is provided an airborne microorganism detection method comprising the steps of.

Step 1: the deployment of the air microorganism detection robot comprises the steps of selecting and configuring modular hardware of the air microorganism detection robot, installing and debugging an operating system and software, configuring reagents and consumables, and is used for completing intelligent automatic continuous dynamic collection and detection of one or more microorganisms in the air.

Step 2: the air microorganism detection robot arrives at a preset position, and the air microorganism detection robot arrives by self through the moving chassis and is assisted to arrive by a third party in a conveying mode.

And step 3: the gas circuit system is started, remote control, field interaction or artificial intelligence autonomous control are adopted, the intelligent gas pump and the intelligent gas valve are opened, air particles enter the acquisition module along with the pipeline, then enter the disinfectant chamber, and finally, tail gas subjected to disinfection treatment is released.

And 4, step 4: the collecting box collects and captures air particles, air flows through the collecting box, the air particles are captured by the filler, and the capturing mode comprises physical blocking adsorption particles formed by the filler and air particles carrying electric charges controlled by an electromagnetic field device.

And 5: collect the box and change, when the predetermined collection period ended, intelligent air pump stopped, the intelligent pneumatic valve was closed, and the manipulator will accomplish the box that collects and take off and turn into biochemical reaction chamber, and the manipulator takes out new box that collects from the storage case and inserts the gas circuit system, restarts intelligent air pump and intelligent pneumatic valve, and new box that collects continues to gather and catches the air particle.

Step 6: the collecting box is arranged in the biochemical reaction chamber, the temperature control device provides proper temperature and humidity, according to the biochemical reaction specification, the sample adding device adds a reagent from the air inlet or the air outlet, and the mechanical arm transfers the collecting box into the elution pool to remove the unbound markers.

And 7: the collecting box is arranged in the photoelectric detection chamber, the collecting box is transferred into the photoelectric detection chamber by the mechanical arm, the filler in the collecting box is subjected to luminescence scanning, and luminescence data are collected.

And 8: and judging and reading the air microorganism detection result, wherein the detection result is obtained by the photoelectric scanning data and the airflow data through the algorithm of the central data storage and processing module of the air microorganism detection robot, and the detection result is obtained by uploading the photoelectric scanning data and the airflow data to the cloud server algorithm.

And step 9: presenting the air microorganism detection result.

Step 10: and (3) reprocessing and recycling reagent consumables, which comprises reprocessing of the collection box, reprocessing of the gene chip and reprocessing of eluent to respectively obtain the reusable collection box, the gene chip and the marker, and transferring the reusable collection box, the gene chip and the marker into a storage box for later use.

In an exemplary embodiment of the present application, in step 1, the modularized hardware includes a mobile chassis, an intelligent interactive screen, a machine vision sensor, a warning lamp, an acquisition module, a detection module, an environmental disinfection device, an environmental monitoring sensor, a power module, a wireless communication module, and a central data storage and processing module.

In an exemplary embodiment of the present application, in step 1, the operating system includes an intelligent traveling apparatus operating system, a manipulator and a robot arm operating system, and the software includes an application program, an algorithm, code, and the like.

In an exemplary embodiment of the present application, in step 4, a deflecting electromagnetic field is applied to the collection box to cause positively and negatively charged air particles to enter and reside within the packing of the collection box, respectively, capturing the different sized air particles in combination with the microspheres in the packing, the physical barrier of the fibers, and the filtration of the filter membrane.

In an exemplary embodiment of the present application, in step 6, the pooling cassette is filled with an antigen-loaded non-precoated microorganism, air particles are eluted, and after pretreatment of the air particle sample, the air particle sample is injected into a gene chip sensor for qualitative or quantitative analysis of the microorganism.

(III) the beneficial effects.

(1) The air microorganism detection robot is provided with an intelligent moving device, has the traffic capacity of roads and buildings, and avoids pathogenic microorganism exposure infection caused by manual operation.

(2) The air path system configured by the air microorganism detection robot adopts an intelligent air pump and an intelligent air valve, can accurately control the flow direction and the flow speed of air flow, adopts a plurality of sampling ports, is beneficial to collecting air particle samples on different air flow layers and even the surface of a floor, adopts microspheres with different diameters, fibers with different densities or filter membranes with different apertures and other filler distributions to assemble a collecting box according to the diameter, the density and the aperture, controls the motion track of air particles carrying positive charges or negative charges by a deflection electromagnetic field device, and improves the efficiency of capturing and collecting the air particles.

(3) The collection box configured by the air microorganism detection robot can be replaced in real time, when the preset collection time period is over, the collection box which finishes collection is taken down by the mechanical arm, the mechanical arm takes out a new collection box from the storage box and accesses the air path system, and the new collection box continues to collect and capture air particles, so that the continuity of the operation flow is ensured.

(4) The biochemical reaction chamber configured by the air microorganism detection robot adopts a highly integrated antigen-antibody reaction sensor, a gene chip sensor and a mechanical arm, so that the size of the robot can be reduced, the weight of the robot is reduced, the consumption of reagents, consumables and energy is reduced, and the detection efficiency is improved.

(5) The filler arranged by the air microorganism detection robot pre-coats a plurality of microorganism antigens, and the chromogenic markers are correspondingly arranged, so that a plurality of microorganisms can be analyzed simultaneously, and the detection efficiency is improved.

(6) The air microorganism detection robot has the functions of reprocessing and recycling reagent consumables, automatically reprocesses the detected collection box, gene chip and eluent, respectively obtains the reusable collection box, gene chip and marker, and transfers the reusable collection box, gene chip and marker into a storage box for standby, thereby reducing the waste of expensive resources and lowering the operation cost.

(7) Environmental monitoring sensor, safety monitoring sensor, the intelligent environmental degassing unit of air microbiological detection robot configuration for its function is more powerful.

(8) The air microbe detection robot is provided with a collecting box which is filled with non-precoated microbe antigen filler, and after the elution air particles are pretreated, the elution air particles are injected into a gene chip sensor and a bioluminescent sensor for qualitative or quantitative analysis of microbes, so that the detection range of a sample is expanded.

(9) The mechanical arm, the hose and the suction nozzle which are configured for the air microorganism detection robot can be used for intelligently collecting air particles deposited on floors, table tops and specific human body surfaces, and the sample collection range of the air microorganism detection robot is expanded.

(10) The detection result of the air microorganism detection robot can be published on the detection site in real time, and can also be uploaded to a cloud server for remote access, so that the efficiency of obtaining specific microorganism warning information in the air by a user is improved.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and together with the description, serve to explain the principles of the application. It is obvious that the drawings in the following description are only some embodiments of the application, and that for a person skilled in the art, other drawings can be derived from them without inventive effort.

Fig. 1A schematically shows a front structure of an airborne microorganism detection robot that can correspond to the present application.

Fig. 1B schematically shows a sectional structure of an airborne microorganism detection robot that can correspond to the present application.

Fig. 2A schematically illustrates one gas circuit system configuration that may correspond to the present application.

Fig. 2B schematically illustrates another air path system configuration that may correspond to the present application.

Fig. 2C schematically illustrates another gas circuit system configuration that may correspond to the present application.

Fig. 2D schematically illustrates another gas circuit system configuration that may correspond to the present application.

Fig. 2E schematically illustrates another gas path system structure that may correspond to the present application.

Fig. 3A schematically shows a pooling cassette configuration which may correspond to the present application.

Fig. 3B schematically shows another pooling cassette configuration that may be applicable to the present application.

Fig. 3C schematically shows another pooling cassette configuration that may correspond to the present application.

Fig. 4A schematically shows an analysis system structure that may correspond to the present application.

Fig. 4B schematically shows another analysis system configuration that may correspond to the present application.

FIG. 5 schematically illustrates an air microorganism detection workflow that may correspond to the present application.

Fig. 6 schematically illustrates an air particle collection procedure that may be applicable to the present application.

Detailed Description

Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many different forms and should not be construed as limited to the examples set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.

It should be noted that the directional phrases in the present embodiment are only relative concepts or reference to the normal use status of the product, and should not be considered as limiting.

Furthermore, the drawings are merely schematic illustrations of the present application and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and thus their repetitive description will be omitted. Some of the block diagrams depicted in the figures are functional entities that do not necessarily correspond to physically or logically separate entities, and may be implemented in software, or in one or more hardware modules or combinations of components.

Fig. 1A and 1B schematically show a general structure of an airborne microorganism detection robot that can be applied to the present application.

As shown in fig. 1A, the air microorganism detection robot in the embodiment of the present application may include a smart screen 1, a microorganism detection robot body 2, an intelligent moving chassis 3, a mechanical arm 4, and a warning light 5, the smart screen 1 and the microorganism detection robot body 2 may be connected by a rotating shaft 6, a shell 21 of the microorganism detection robot body 2 may include a sampling port 21-1A, a sampling port 21-1B, a sampling port 21-1C, a hose 21-3, a suction nozzle 21-4, and a tail gas port 21-2, the intelligent moving chassis 3 may include a plurality of driving wheels 31, and the warning light 5 and the microorganism detection robot body 2 may be connected by a bracket 7.

It should be noted that, wisdom screen 1 can set up a plurality ofly, and wisdom screen 1 can also set up in the shell 21 surface of little biological detection robot body 2, and wisdom screen 1 can also set up vision sensor, ultrasonic sensor, laser radar, environmental monitoring sensor.

It should be noted that the number of the sampling ports 21-1 and the positions of the parts can be adjusted according to the requirement, for example, the sampling ports 21-1 can be disposed on the smart screen 1 or the rack 7 so as to collect the air particles at the high position, and the sampling ports 21-1 can be disposed on the side surface or the bottom surface of the smart mobile chassis 3 so as to collect the air particles at the low position.

It should be noted that the intelligent mobile chassis 3 may include a power supply and a charging device, and the driving wheel 31 may be replaced by a crawler, a four-foot device or a six-foot device according to task requirements.

It should be noted that the hose 21-3 and the suction nozzle 21-4 may be connected to the robot arm 4, and the robot arm 4 may operate the hose 21-3 and the suction nozzle 21-4 to perform the air particle collecting operation. The microorganism detection robot body 2 can be provided with an air disinfection device, and the mechanical arm 4 controls the air disinfection device to implement the ambient air disinfection operation and the disinfection and sterilization operation of the air microorganism detection robot.

It is understood that the intelligent mobile chassis 3 may be replaced by an unmanned vehicle, which may transport the microbe detection robot body 2 to a task site for airborne microbe detection. The intelligent screen 1 can be omitted, so that the cost is reduced, the size of the air microorganism detection robot is reduced, and the weight of the air microorganism detection robot is reduced. The mechanical arm 4 can be omitted, so that the cost is reduced, the size of the air microorganism detection robot is reduced, and the weight of the air microorganism detection robot is reduced.

In addition, the bracket 7 can be provided with a lighting lamp and a wireless communication device.

As shown in fig. 1B, the air microorganism detection robot body 2 according to the embodiment of the present disclosure may include, but is not limited to, an air particle collection module 100, a detection module 200, an interpretation module 300, a recycling processing module 400, a manipulator 22, a storage box 23, a result issuing module, a sterilization module, a waste box, a wireless communication module, and a central data storage processing module, the collection module 100 may include, but is not limited to, an air channel system, a collection box 120, the detection module 200 may include, but is not limited to, a biochemical reaction chamber, which may include, but is not limited to, an antigen-antibody reaction sensor, a gene chip sensor, a temperature control device, a sample adding device, and an elution tank, the interpretation module 300 includes, but is not limited to, a photoelectric detection chamber, the recycling processing module 400 may include, but is not limited to, a reprocessing device, which may include, but is not limited to, a washing tank, a centrifuge, a device, a data processing module, Disinfection equipment, quality inspection equipment and packaging equipment.

It should be noted that the collection module 100 may include a plurality of sets of independent air path systems, or a series or parallel connection of air path systems, and may include a plurality of collection boxes 120.

It should be noted that the detection module 200 may include a plurality of biochemical reaction chambers, a plurality of antigen-antibody reaction sensors, a plurality of gene chip sensors, a plurality of sample adding devices, and a plurality of elution pools, so as to implement parallel operations. The detection module 200 may include a conventional microbial cultivation device to detect living microbes and detect the total amount of airborne microbes using a chemiluminescent sensor.

In addition, the biochemical reaction chamber of the detection module 200, the manipulator 22, the photoelectric detection chamber of the interpretation module 300, etc. may be integrally designed as an intelligent sensor, implementing a line-production type microorganism detection and result interpretation.

It should be noted that the photoelectric detection device of the photoelectric detection chamber of the interpretation module 300 can be disposed on the manipulator 22, and the manipulator 22 operates the photoelectric detection device to perform the light source emitting and scanning operations.

It should be noted that the recycling processing module 400 can process and test the collection cassette 120, the antigen-antibody reaction sensor, the gene chip sensor, and the chemiluminescence sensor, so that the collection cassette 120, the antigen-antibody reaction sensor, the gene chip sensor, and the chemiluminescence sensor can be reused.

It should be noted that the manipulator 22 may be provided in plural, and different degrees of freedom and different end effectors may be selected according to task requirements.

The reserve tank 23 may store the collection cassette 120, reagents, consumables, sensors, and accessories.

It should be noted that the result issuing module can display and issue the detection result of the air microorganism detection robot in real time on the smart screen 1, and can also upload the detection result to the cloud server for the user to remotely access.

It should be noted that the sterilization module can be used for sterilizing the gas circuit system and also can be used for sterilizing the inner space of the air microorganism detection robot body 2.

It should be noted that the data generated by the air microorganism detection robot can be stored and operated in time by the central data storage and processing module, or the data can be issued to the cloud server by the wireless communication module, the cloud server performs storage and operation processing, and the operation processing result is sent to the air microorganism detection robot, and the detection result is issued in real time by the smart screen 1 of the air microorganism detection robot.

Fig. 2A-2E schematically illustrate one gas path system configuration that may correspond to the present application.

As shown in FIG. 2A, the air path system may include a sampling port 21-1, an intelligent air pump 110, a collection box 120, a disinfection liquid chamber 130, an exhaust port 21-2, and a connecting pipe 140, wherein the air flow passes through the sampling port 21-1, the collection box 120 captures and collects air particles, and the air flow enters the disinfection liquid chamber 130 and is discharged through the exhaust port 21-2.

As shown in FIG. 2B, the air path system may include a sampling port 21-1, an intelligent air pump 110, a collection box 120, an electromagnetic field device 150-1, an electromagnetic field device 150-2, a disinfection liquid chamber 130, an exhaust port 21-2, and a connecting pipe 140, wherein when the air flow passes through the sampling port 21-1, the collection box 120 captures and collects air particles, the electromagnetic field device 150-1 and the electromagnetic field device 150-2 are activated to respectively make the positively charged air particles and the negatively charged air particles stay at corresponding positions of the collection box 120 under the action of the electric charge force, and the air flow enters the disinfection liquid chamber 130 for disinfection treatment and is released through the exhaust port 21-2.

It is understood that the sampling port 21-1 may be provided with an electric induction device, so that the air particles entering the air path system carry electric charges, which is beneficial for the electromagnetic field device 150-1 and the electromagnetic field device 150-2 to efficiently assist the collection box 120 in capturing and collecting the air particles.

As shown in FIG. 2C, the air path system may include a sampling port 21-1A, a sampling port 21-1B, an intelligent air pump 110-1, an intelligent air pump 110-2, an intelligent air valve 160, a collection box 120, a disinfection liquid chamber 130, an exhaust port 21-2, and a connecting pipe 140, wherein the air flow passes through the sampling port 21-1A, the sampling port 21-1B, the intelligent air pump 110-1, the intelligent air pump 110-2, and the intelligent air valve 160, is captured and collected by the collection box 120, and enters the disinfection liquid chamber 130, and is released through the exhaust port 21-2.

It should be noted that a plurality of sampling ports 21-1 may be provided, and two sampling ports 21-1 are taken as an example here.

As shown in FIG. 2D, the air path system may include a sampling port 21-1A, a sampling port 21-1B, an intelligent air pump 110-1, an intelligent air pump 110-2, an intelligent air valve 160-1, an intelligent air valve 160-2, a collection box 120-1, a collection box 120-2, a disinfection liquid chamber 130, an exhaust port 21-2 and a connecting pipe 140, wherein air flows through the sampling port 21-1A, the sampling port 21-1B, the intelligent air pump 110-1, the intelligent air pump 110-2, the intelligent air valve 160-1 and the intelligent air valve 160-2 respectively into the collection box 120-1 and the collection box 120-2, and air particles are captured and collected by the collection box 120, and the air flows enter the disinfection liquid chamber 130 and are released through the exhaust port 21-2.

It should be noted that a plurality of sampling ports 21-1 may be provided, here, two sampling ports 21-1 are taken as an example, and a plurality of collection boxes 120 are provided, here, two collection boxes 120 are taken as an example.

As shown in fig. 2E, the air path system may include a suction nozzle 21-4, a hose 21-3, an intelligent air pump 110, a collection box 120, a disinfection liquid chamber 130, an exhaust port 21-2, and a connecting pipe 140, wherein the suction nozzle 21-4 and the hose 21-3 are controlled by the robot arm 4, the suction nozzle 21-4 approaches a target space, the intelligent air pump 110 is started, air flows through the suction nozzle 21-4, the hose 21-3 and the collection box 120, the collection box 120 captures and collects air particles, and then the air flows enter the disinfection liquid chamber 130 and is released through the exhaust port 21-2.

Fig. 3A-3C schematically show a pooling cassette configuration that may correspond to the present application.

As shown in FIG. 3A, the collection box 120 may include an inlet 120-2, a wall 120-1, an outlet 120-3, and a filler 120-4, the filler 120-4 may include large-diameter microspheres 120-4-1A, medium-diameter microspheres 120-4-1B, and small-diameter microspheres 120-4-1C, and the large-diameter microspheres 120-4-1A are classified according to the diameter of the filler 120-4 and loaded into the collection box 120, wherein the large-diameter microspheres 120-4-1A are close to the inlet 120-2, and the small-diameter microspheres 120-4-1C are close to the outlet 120-3.

It is understood that the inlet port 120-2 and the outlet port 120-3 may be provided in plurality, and the packing 120-4 may include more diameter classification categories.

It should be noted that the wall 120-1 and the filler 120-4 of the collection box 120 may be made of colorless transparent materials, so as not to affect the light transmittance during photoelectric detection. The large diameter microspheres 120-4-1A, the medium diameter microspheres 120-4-1B, and the small diameter microspheres 120-4-1C may include a void structure, may be coated with at least one microbial antigen, and may be used to analyze at least one microorganism.

As shown in FIG. 3B, the collection box 120 may include an inlet 120-2, a wall 120-1, an outlet 120-3, and a filler 120-4, the filler 120-4 may include a sparse fiber 120-4-2A, a moderately dense fiber 120-4-2B, and a highly dense fiber 120-4-2C, and may be packed into the collection box 120 according to the density classification of the filler 120-4, wherein the sparse fiber 120-4-2A is adjacent to the inlet 120-2 and the highly dense fiber 120-4-2C is adjacent to the outlet 120-3.

It is understood that the inlet 120-2 and the outlet 120-3 may be provided in plurality, and the packing 120-4 may include more density types.

It should be noted that the wall 120-1 and the filler 120-4 of the collection box 120 may be made of colorless transparent materials, so as not to affect the light transmittance during photoelectric detection. The sparse fiber 120-4-2A, the moderately dense fiber 120-4-2B, and the highly dense fiber 120-4-2C may include an adsorbent structure that may be coated with at least one microbial antigen for analysis of at least one microorganism.

As shown in FIG. 3C, the collection box 120 may include an inlet 120-2, a wall 120-1, an outlet 120-3, and a filler 120-4, the filler 120-4 may include a large-aperture filter 120-4-3A, a medium-aperture filter 120-4-3B, and a small-aperture filter 120-4-3C, and may be classified according to the aperture of the filler 120-4 and loaded into the collection box 120, wherein the large-aperture filter 120-4-3A is close to the inlet 120-2, and the small-aperture filter 120-4-3C is close to the outlet 120-3.

It is understood that the inlet 120-2 and outlet 120-3 may be provided in plurality and the packing 120-4 may include more pore size classes.

It should be noted that the wall 120-1 and the filler 120-4 of the collection box 120 may be made of colorless transparent materials, so as not to affect the light transmittance during photoelectric detection. The large pore filter 120-4-3A, the medium pore filter 120-4-3B and the small pore filter 120-4-3C may include an adsorption adhesive structure, may be coated with at least one microbial antigen, and may be used to analyze at least one microorganism.

Fig. 4A and 4B schematically show an analysis system structure that can be applied to the present application.

As shown in fig. 4A, the analysis system may include an acquisition module 100, a detection module 200, an interpretation module 300, a recycling process module 400, and a manipulator 22.

The collection module 100 may include a collection box 120, wherein the air inlet 120-2 of the collection box 120 receives the airflow from the sampling port 21-1, and the airflow is filtered by the collection box 120 and then discharged from the air outlet 120-3 into the sanitizer chamber 130.

The collection box 120 for capturing and collecting air particles can be transferred to the detection module 200 by the manipulator 22, the detection module 200 can include a biochemical reaction chamber, the biochemical reaction chamber can include a sample adding device, a temperature control device and an elution pool, the sample adding device can add a reagent to the collection box 120 through the air inlet 120-2 or the air outlet 120-3, the reagent can include a buffer solution, a labeled antibody, a labeled antigen, a reaction substrate and an enzyme, after incubation, the sample adding device can add an eluent to the collection box 120 through the air inlet 120-2 or the air outlet 120-3, and free labeled antibody, labeled antigen, reaction substrate and enzyme can be washed out.

The washed collection box 120 can be transferred to the interpretation module 300 by the manipulator 22, the interpretation module 300 can include a light source device, a photoelectric scanning detection device, a visual sensor and a counter, the light source device can emit light, the light can include laser, visible light, X-ray, ultraviolet light and infrared light with different wavelengths, the photoelectric scanning detection device, the visual sensor and the counter can collect specific microbial luminescence signal data combined on the packing 120-4 through the wall 120-1 and the packing 120-4 of the collection box 120, and the collected luminescence signal data can be transmitted to a central data storage processing module or a cloud server.

The collection box 120 for collecting the luminescence signal data may be transferred to the recycling processing module 400 by the manipulator 22, and the recycling processing module 400 may include a collection box reprocessing device, a gene chip processing device, an eluent reprocessing device, a detection sensor processing device, and a reusable collection box, a gene chip, an antigen or antibody marker, and a detection sensor, which are reprocessed and reused, may be transferred to the storage box 23 by the manipulator 22 for standby.

It should be noted that the biochemical reaction chamber of the detection module 200 may include a gene chip and a microfluidic biochip, the eluent in the collection box 120 may enter the gene chip and the microfluidic biochip, and after the biochemical reaction of the gene chip and the microfluidic biochip is completed, the gene chip and the microfluidic biochip may be transferred to the interpretation module 300 by the manipulator 22, and specific microbial signal data of the gene chip and the microfluidic biochip may be read.

In addition, it is understood that when the air particle microorganism is detected by using the gene chip or the microfluidic biochip, the collection box 120 may use the filler 120-4 without pre-coating the microorganism antigen, and the recycling processing module 400 may be omitted to save the cost.

It should be noted that the recycling module 400 may include a quality detection device that can test the performance of the reprocessed collection cassette, genechip, antigen or antibody marker, and detection sensor, and if the performance of the reprocessed collection cassette, genechip, antigen or antibody marker, and detection sensor does not meet the recycling criteria, the collection cassette, genechip, antigen or antibody marker, and detection sensor can be transferred to the waste cassette by the robot 22.

As shown in fig. 4B, the analysis system may include an acquisition module 100, a detection module 200, a recycling process module 400, and a manipulator 22.

The collecting box 120 for capturing and collecting air particles can be transferred to the separating pool 220 of the detection module 200 by the manipulator 22, the separating pool 220 can dissolve the air particles captured and collected by the collecting box 120 into a buffer solution, the buffer solution containing the air particles can be centrifugally concentrated to prepare a sample, the sample can be transferred to the microbial chemiluminescence sensor 240 and the microbial gene test sensor 260 by an intelligent pipette, the microbial chemiluminescence sensor 240 can acquire microbial total data by adopting a biological energy luminescence technology of microorganisms, or acquire specific microbial data by adopting a biological energy luminescence spectrum technology, and the microbial gene test sensor 260 can acquire the microbial total data by including a test microbial conserved sequence or acquire the specific microbial data by including a test microbial specific sequence.

The collection cassette 120 of dissolved air particles can be transferred from the separation cell 220 to the recovery processing module 400 by the robot 22 and the reprocessed and recycled reusable collection cassette can be transferred by the robot 22 to the storage tank 23 for use.

As shown in fig. 5, the airborne microorganism detection process 1000 includes the following steps.

1100: the deployment of the air microorganism detection robot can comprise the selection and configuration of modularized hardware, the installation and debugging of an operating system and software, the configuration of reagents and consumables of the air microorganism detection robot, and can be used for completing the intelligent automatic continuous dynamic collection and detection of one or more microorganisms in the air.

1200: the air microorganism detection robot reaching the predetermined position may include self-arrival of the air microorganism detection robot by means of a mobile chassis, and third-party transportation assistance arrival.

1300: the air microorganism detection robot collects air particles.

1400: the air microorganism detection robot detects and analyzes microorganisms.

1500: presenting the air microorganism detection result.

1600: and (5) reprocessing and recycling reagent consumables.

It should be noted that in step 1100, the modularized hardware may include a mobile chassis, an intelligent interactive screen, a warning lamp, a collection module, a detection module, an environmental disinfection device, an environmental monitoring sensor, a power module, and a wireless communication module. The operating system may include an intelligent locomotion device operating system, a robotic arm and a robotic arm operating system, and the software may include applications, algorithms, code, and the like. In addition, it is understood that the smart rover operating system, the robot and the robotic arm operating system may select the same operating system.

As shown in fig. 6, the air particle process 1300 may include the following steps.

1310: the gas circuit system starts A, can adopt remote control, field interaction, or artificial intelligence is from the main control, can include that intelligence air pump and intelligent pneumatic valve open, and the air particle gets into collection module along with the pipeline, then, can get into the disinfection liquid chamber, finally, can release the tail gas through disinfection processing.

1320: gas circuit system starts B, and the arm can carry the hose and make the suction nozzle be close to the article surface, and article surface air particle opens through intelligent air pump and intelligent pneumatic valve, and the air particle gets into collection module along with the pipeline, then, can get into the disinfection liquid chamber, and finally, can release the tail gas through disinfection.

1330: the collecting box collects and captures air particles, and air particles can be captured by filler through the collecting box, and the capturing mode comprises physical blocking adsorption particles formed by the filler and deflection electromagnetic field control charge-carrying air particles.

1340: collect the box and change, when the predetermined collection period ended, the intelligence air pump stopped, the intelligence pneumatic valve was closed, and the manipulator can take off the box that collects of accomplishing and turn into biochemical reaction chamber, and the manipulator can take out new box access gas circuit system that collects from the storage case, restarts intelligence air pump and intelligence pneumatic valve, and new box that collects can continue to gather and catch the air particle.

In addition, in step 1330, a deflecting electromagnetic field is applied to the collection box to allow airborne particles carrying positive and negative charges, respectively, to enter and reside within the packing of the collection box, which may trap airborne particles of different sizes in conjunction with microspheres in the packing, physical blocking of fibers, and filtration by the filter membrane.

It should be noted that the air microorganism detection robot flow 1400 for detecting and analyzing air particles may include the following steps.

1410: the collecting box is arranged in the biochemical reaction chamber, the temperature control device can provide proper temperature and humidity, according to the biochemical reaction specification, the sample adding device can add reagents from the air inlet or the air outlet, and the mechanical arm can transfer the collecting box into the elution pool to remove unbound markers.

1420: the collecting box is arranged in the photoelectric detection chamber, the mechanical arm can transfer the collecting box into the photoelectric detection chamber, the filler in the collecting box can be subjected to luminescence scanning, and luminescence data can be collected.

1430: and judging and reading the air microorganism detection result, wherein the judgment can comprise that the photoelectric scanning data and the air flow data are obtained by the algorithm of a central data storage and processing module of the air microorganism detection robot, and the photoelectric scanning data and the air flow data are uploaded to a cloud server algorithm to obtain the detection result.

In addition, the collection box can be placed with a non-precoated microbial antigen filler, and in step 1410, the air particles are eluted, and after the air particle sample is pretreated, the air particle sample can be injected into a gene chip sensor or a bioluminescent sensor for qualitative or quantitative analysis of the microbes.

In addition, the pooling cassette may be loaded with a non-precoated microbial antigen pad, and in step 1410, the eluted air particle sample is added to a petri dish to obtain a plurality of microbes for further analysis.

It is noted that the process 1500 for presenting air microorganism detection results may include the following steps.

1510: the intelligent screen of the air microorganism detection robot can display the air microorganism detection result in real time.

1520: the air microorganism detection result data can be sent to the client of the user in real time through the wireless communication module.

1530: the air microorganism detection result data can be uploaded to the cloud server through the wireless communication module, a user can download the data from the cloud server through the client, and the cloud server can provide remote access in real time.

1540: the central data storage and processing module of the air microorganism detection robot can store detection result data, and the detection result data of the central data storage and processing module can be copied after the air microorganism detection robot completes an operation task.

It should be noted that, in step 1600, the recycling of the reagent consumables may include reprocessing of the collection cassette, reprocessing of the gene chip and reprocessing of the eluent, so as to obtain the reusable collection cassette, gene chip and marker, respectively, and transfer them to the storage box for later use.

It is understood that in step 1600, after reprocessing the pooled cassette reagent consumables, quality assessments may be performed to transfer to a holding tank for use if the quality criteria for reuse are met, and to transfer to a waste cassette for disposal as medical waste if the quality criteria for reuse are not met.

It should be noted that although in the foregoing detailed description reference has been made to a number of apparatus devices, components or assemblies for execution of method flows, such a division is not mandatory. Indeed, the features and functions of two or more apparatus devices, components or assemblies described above may be embodied in one apparatus device, component or assembly according to embodiments of the application. Conversely, the features and functions of one apparatus device, component or assembly described above may be further divided into embodiments by a plurality of apparatus devices, components or assemblies.

Further, although the various steps of the method flows in this application are depicted in the drawings in a particular order, this does not require or imply that these steps must be performed in this particular order, or that all of the depicted steps must be performed, to achieve desirable results. Additionally or alternatively, certain steps may be omitted, multiple steps combined into one step execution, and/or one step broken down into multiple step executions, etc.

The flowchart and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of apparatus, methods and system products according to various embodiments of the present application. In this regard, each block in the flowchart or block diagrams may represent a module, device, or portion of a system that comprises one or more executable processes for implementing the specified actions. It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks or components shown in succession may, in fact, be executed substantially concurrently, or the blocks or components may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams or flowchart illustration, and combinations of blocks in the block diagrams or flowchart illustration, can be implemented by special purpose hardware-based systems which perform the specified functions or acts, or combinations of special purpose hardware and computer instructions.

The processes described in the embodiments of the present application may be implemented by software or hardware. The names of these processes or hardware devices do not in some cases constitute limitations of the processes or hardware devices themselves.

Other embodiments of the present application will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. This application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the disclosure being indicated by the following claims.

Claims

1. An airborne microorganism detection robot for airborne microorganism collection, capture and detection, the airborne microorganism detection robot comprising:

the mobile chassis comprises an intelligent moving device;

the gas path system comprises a sampling port, an intelligent gas pump, an intelligent gas valve, a disinfectant chamber, a tail gas port and a connecting pipeline;

the analysis system comprises an acquisition module, a detection module, an interpretation module and a report module, wherein the acquisition module comprises a collection box, one end of the collection box is an air inlet, the other end of the collection box is an air outlet, the collection box is preloaded with a filler, and the filler comprises microspheres, fibers and a filter membrane; the detection module comprises a robot hand, a biochemical reaction chamber and a photoelectric detection chamber, the robot hand transports the collection box, and the biochemical reaction chamber comprises an antigen-antibody reaction sensor and a gene chip sensor.

2. The airborne microorganism detection robot of claim 1, wherein the number of said sampling port, said intelligent air pump, said intelligent air valve, said collection box, said robot hand is at least two;

the collecting box and the filler are made of colorless transparent materials;

the filler is pre-coated with at least one microbial antigen.

3. The airborne microbial detection robot of claim 1, wherein said microspheres include large-diameter microspheres, small-diameter microspheres, sorted according to microsphere diameter into collection boxes;

the fibers comprise sparse fibers and dense fibers, and are loaded into a collecting box according to fiber density classification;

the filter membranes comprise large-aperture filter membranes and small-aperture filter membranes, and are classified and loaded into the collection box according to the aperture of the filter membranes.

4. The airborne microorganism detection robot of claim 1, further comprising a robotic arm, a hose, a suction nozzle, which can be used for intelligent collection of air particles on the surface of an object; and

the device adopts a natural sedimentation method and an air impact method, and collects and captures air particles by using a culture dish and analyzes microorganisms in the air.

5. The airborne microbe detection robot of claim 1, further comprising environmental monitoring sensors for monitoring temperature, humidity, noise, air pollutant levels; and

and the safety monitoring sensor is used for monitoring toxic gas, radiation and fire.

6. The air microbe detection robot of claim 1, further comprising an intelligent environmental disinfection device to perform disinfection operations.

7. An air microorganism detection method for completing collection, capture, detection and analysis of microorganisms in air, which is characterized by comprising the following steps:

step 1: the air microorganism detection robot deployment comprises selecting and configuring modular hardware of the air microorganism detection robot, installing and debugging an operating system and software, configuring reagents and consumables;

step 2: the air microorganism detection robot arrives at a preset position, and the air microorganism detection robot arrives by self through a mobile chassis and is assisted by third-party transportation;

and step 3: the gas path system is started, remote control, field interaction or artificial intelligent autonomous control is adopted, the method comprises the steps that an intelligent gas pump and an intelligent gas valve are opened, air particles enter an acquisition module along with a pipeline, then enter a disinfectant chamber, and finally, tail gas subjected to disinfection treatment is released; the mechanical arm carries the hose to enable the suction nozzle to be close to the surface of the article, and after the air path system is started, air particles on the surface of the article enter the acquisition module along with the pipeline;

and 4, step 4: collecting and capturing air particles by a collecting box, wherein the air particles comprise air flowing through the collecting box, the air particles are captured by filler, and the capturing mode comprises physical barrier adsorption particles formed by the filler and deflection electromagnetic field control air particles carrying charges;

and 5: the collection box is replaced, when the preset collection time period is over, the intelligent air pump is stopped, the intelligent air valve is closed, the collection box which is collected is taken down by the mechanical arm and transferred to the biochemical reaction chamber, the mechanical arm takes out a new collection box from the storage box and accesses the air path system, the intelligent air pump and the intelligent air valve are started again, and the new collection box continues to collect and capture air particles;

step 6: the collecting box is arranged in a biochemical reaction chamber, a temperature control device provides proper temperature and humidity, according to the biochemical reaction specification, a sample adding device adds a reagent from an air inlet or an air outlet, and a mechanical arm transfers the collecting box into an elution pool to remove unbound labels;

and 7: the collecting box is arranged in the photoelectric detection chamber, the collecting box is transferred into the photoelectric detection chamber by the mechanical arm, the filler in the collecting box is subjected to luminescence scanning, and luminescence data are collected;

and 8: judging and reading the air microorganism detection result;

and step 9: presenting an airborne microbial detection result;

step 10: and (5) reprocessing and recycling reagent consumables.

8. The airborne microbe detection method of claim 7, wherein in step 1, the modular hardware comprises a mobile chassis, an intelligent interactive screen, a warning lamp, a collection module, a detection module, an environmental disinfection device, an environmental monitoring sensor, a power module, and a wireless communication module.

9. The airborne microorganism detection method of claim 7, wherein in step 4, a deflecting electromagnetic field is applied to the collection chamber to cause positively and negatively charged airborne particles to enter and reside within the packing material of the collection chamber, respectively, and the airborne particles are captured in combination with microspheres in the packing material, physical barrier of fibers, and filtration through a filter membrane.

10. The airborne microbe detection method of claim 7 wherein in step 6, the collection cassette is loaded with non-precoated microbe antigen filler, air particles are eluted, and after pretreatment of the air particle sample, the air particle sample is injected into a gene chip sensor or a bioluminescent sensor for qualitative or quantitative analysis of microbes.