CN113500758A - Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device - Google Patents

Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device Download PDF

Info

Publication number
CN113500758A
CN113500758A CN202110614039.2A CN202110614039A CN113500758A CN 113500758 A CN113500758 A CN 113500758A CN 202110614039 A CN202110614039 A CN 202110614039A CN 113500758 A CN113500758 A CN 113500758A
Authority
CN
China
Prior art keywords
composite material
nafion
acid composite
perfluorosulfonic acid
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110614039.2A
Other languages
Chinese (zh)
Inventor
潘辉
尹国校
何青松
于敏
刘小芳
陆吉
张昊
吴雨薇
孙正
赵泽芳
田成博
仲启云
胡润淇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing University of Aeronautics and Astronautics
Original Assignee
Nanjing University of Aeronautics and Astronautics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing University of Aeronautics and Astronautics filed Critical Nanjing University of Aeronautics and Astronautics
Priority to CN202110614039.2A priority Critical patent/CN113500758A/en
Publication of CN113500758A publication Critical patent/CN113500758A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/05—Filamentary, e.g. strands
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/118—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C18/00—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating
    • C23C18/16—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by reduction or substitution, e.g. electroless plating
    • C23C18/31—Coating with metals
    • C23C18/42—Coating with noble metals
    • C23C18/44—Coating with noble metals using reducing agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention discloses a perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device, and belongs to the field of 3D printing intelligent material application. A fused deposition additive manufacturing technology of a perfluorosulfonic acid composite material is developed, and the process flow comprises the following steps: (1) performing extrusion molding on the Nafion precursor wire; (2) printing a Nafion precursor film; (3) hydrolyzing a Nafion precursor membrane; (4) and (3) manufacturing a conductive electrode to realize the rapid manufacturing of the perfluorosulfonic acid composite material. The perfluorosulfonic acid composite material is attached to the electrode and embedded into the fixed guide head, the lead is connected with the electrode through the guide tube, active bending of the surgical guide tube is realized by adjusting an electric signal, the surgical guide tube based on the perfluorosulfonic acid composite material can relieve the pain degree of a patient in the process of inserting and extracting the guide wire, can greatly reduce the difficulty of minimally invasive intervention operation, reduce the dependence on the operation skill of a doctor, reduce the operation risk, improve the safety and the success of the operation and has higher commercial popularization and application values.

Description

Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device
Technical Field
The invention relates to the field of application of 3D printing intelligent materials, in particular to a perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device.
Background
The perfluorosulfonic acid composite is generally composed of a cation exchange membrane (Nafion) membrane whose shape determines the shape and use of the perfluorosulfonic acid composite produced, and noble metal (platinum, palladium, gold) electrode layers on either side of the membrane. The traditional method for manufacturing the Nafion membrane mainly comprises casting, but the method not only needs to manufacture a mould and consumes time and labor, but also cannot manufacture the Nafion membrane with a complex shape or structure, so that the actual application requirement is difficult to meet, and the application of the perfluorosulfonic acid composite material is greatly limited. In order to manufacture perfluorosulfonic acid composite Materials of complex shape or structure, many researchers have conducted research on the manufacturing method of Nafion membrane, mainly hot pressing method to stack several sheets of Nafion membrane together in order to obtain Nafion membrane of larger thickness (Lee S J, Han M J, Kim S J, et al. analysis method for IPMC activators and application to specific instruments. smart Materials and Structures,2006,15(5):1217 @), extrusion molding to stack Nafion mixed solution layer by layer into Nafion membrane (nano E, lipid on h. free surface preparation of polymer-metal composites. rapid Prototyping Journal,2006,12(5): 253, and spraying method to obtain Nafion membrane of complex shape, sodium-coating and Structures. injection method for coating. 2016,25(8): 085006), etc., but the above methods have certain disadvantages, such as the hot pressing method and the spraying method still need to make a mold, and can not make a Nafion film with a complex structure; the molding shape cannot be controlled by extrusion molding, and the surface quality and the driving performance of the solidified model are poor, so that the actual application requirements cannot be met. In order to solve the problems that the manufacturing of a mould is time-consuming and labor-consuming and the perfluorosulfonic acid composite material with a complex shape or structure is difficult to manufacture, a method for manufacturing the perfluorosulfonic acid composite material by using a fused deposition modeling technology (3D printing) is provided, so that the manufacturing efficiency of the perfluorosulfonic acid composite material is improved, the manufacturing cost is reduced, and the method is applied to an interventional catheter guiding device.
The traditional interventional catheter belongs to a passive type, needs to be matched with an interventional guide wire, is poor in operability, cannot be used for selecting a blood vessel branch, has high requirements on the operation technology of a doctor, and seriously influences the safety and the effectiveness of interventional therapy. The interventional operation catheter based on the perfluorosulfonic acid composite material has no interventional guide wire, can complete blood vessel branch selection only by means of a front perfluorosulfonic acid composite material guide device, can greatly reduce the difficulty of minimally invasive interventional operation, reduces the dependence on the operation skill of a doctor, improves the safety and the success of the operation while reducing the operation risk, and has higher commercial application and popularization values.
Disclosure of Invention
The invention aims to solve the technical problem of the background technology, and provides a perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device to overcome the defects that the prior art is time-consuming and labor-consuming and cannot manufacture perfluorosulfonic acid composite materials with complex shapes or structures. The perfluorinated sulfonic acid composite material is manufactured by a fused deposition molding technology, wherein the perfluorinated sulfonic acid composite material is attached to an electrode and embedded into a fixed guide head, a lead is connected with the electrode through a conduit, and the active bending function of the interventional operation conduit is realized by adjusting an electric signal.
The invention adopts the following technical scheme for solving the technical problems:
a perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device mainly comprise the following steps:
step 1, manufacturing a Nafion precursor wire: extruding Nafion precursor particles into Nafion precursor wires with the diameters of 1.75mm, 2.0mm, 2.5mm and 2.85mm at a proper melting temperature by using an extruder;
step 2, printing the Nafion precursor wire by layers under appropriate printing parameters to form a Nafion precursor film by utilizing a fused deposition modeling technology;
step 3, hydrolysis of the Nafion precursor membrane: putting the printed Nafion precursor membrane into hydrolysis liquid at the temperature of 80 ℃ for hydrolysis, and then washing with deionized water;
and 4, manufacturing a platinum metal electrode on the surface of the Nafion membrane by using a chemical plating method, or hot-pressing TPU-CNT flexible conductive membranes on two sides of the Nafion membrane by using a hot-pressing method, so as to realize the manufacturing of the perfluorosulfonic acid composite material.
The reason why the suitable melting temperature of the Nafion precursor particles in the step 1 is set to 230 to 250 ℃ is that: the method not only ensures that the Nafion precursor wire has better uniformity, but also avoids the oxidation phenomenon of the Nafion precursor wire. The melting temperature is too low, so that Nafion precursor particles are not fully melted, and the surface of the manufactured Nafion precursor wire is rough, so that the printing precision and the surface quality of the Nafion precursor film are influenced; and the setting of the melting temperature is too high, so that the Nafion precursor wire is seriously oxidized, and the driving performance of the perfluorosulfonic acid composite material is further influenced.
The appropriate printing parameter in the step 2 is that the diameter of a nozzle of the printer is 0.4-0.6 mm, so that smooth discharging of the Nafion precursor wire is ensured, and the Nafion precursor wire is prevented from being blocked in the printing process; the printing temperature is 275-305 ℃, so that the Nafion precursor wire can be fully melted in the printing process, and the wire is prevented from being blocked; the temperature of the hot bed is 40-60 ℃, so that the first-layer adhesive force of the Nafion precursor film is increased, and the Nafion precursor film is prevented from warping; the printing speed is 20-50 mm/s, and this is because the printing of flexible material needs lower speed, prevents that the jam phenomenon from appearing in the Nafion precursor wire rod, improves the printing quality of Nafion precursor membrane simultaneously.
The reason for the hydrolysis in step 3 above is: since the Nafion precursor membrane is completely hydrophobic and chemically inert and does not have ion exchange capacity, the Nafion precursor membrane must be converted into a Nafion membrane having ion exchange capacity by hydrolysis in order to perform the manufacture of the perfluorosulfonic acid composite.
The hydrolysis in the step 3 comprises the following specific steps: mixing potassium hydroxide, dimethyl sulfoxide and deionized water according to mass fractions of 15%, 35% and 50% respectively to prepare hydrolysate; putting the Nafion precursor membrane printed by 3D into hydrolysate at 80 ℃ to convert the Nafion precursor membrane into a Nafion membrane; and then washing with deionized water in order to remove residual hydrolysate on the surface of the Nafion membrane.
In the step 4, the specific steps of manufacturing the platinum metal electrode on the surface of the Nafion film by using a chemical plating method are as follows: putting the hydrolyzed Nafion membrane into the prepared platinum ammonia solution for 12 hours to ensure that platinum ammonia ions are fully adsorbed in the Nafion membrane; followed by the use of NaBH4Reducing platinum ammonia ions in the Nafion membrane into metal platinum particles to be deposited on the surface of the Nafion membrane to complete the manufacture of the perfluorosulfonic acid composite material, and storing the manufactured perfluorosulfonic acid composite material in deionized water for later use.
In the step 4, the specific steps of manufacturing the flexible electrodes on the two sides of the Nafion film by using a hot pressing method are as follows: respectively placing the TPU-CNT flexible conductive film on the upper side and the lower side of a Nafion film, and coating a proper amount of concentrated Nafion solution between the Nafion film and the conductive film; and then, realizing the hot-pressing fusion of the Nafion film and the flexible conductive film by utilizing a hot press at certain temperature and pressure.
Compared with the prior art, the invention adopting the technical scheme has the following technical effects:
1. the 3D printing technology has low cost and high reliability and is easy to realize the modeling of the regular perfluorosulfonic acid composite material;
2. the perfluorosulfonic acid composite material with complex shape can be manufactured, and the manufacturing cost and time are reduced;
3. the printed perfluorinated sulfonic acid composite material has good driving capability, can be directly used for an active guiding device of an interventional operation catheter, realizes the active guiding function of the interventional operation catheter, reduces the operation risk, improves the safety and the success of the operation, and has higher commercial application and popularization value.
Drawings
Fig. 1 is a cross-sectional SEM image of an additively manufactured perfluorosulfonic acid composite.
Fig. 2 is a graph comparing the ion exchange capacity of hydrolyzed Nafion membrane to commercial membranes.
FIG. 3 is a graph of the output displacement of perfluorosulfonic acid composites made using fused deposition modeling.
Fig. 4 is an output force diagram of a perfluorosulfonic acid composite manufactured using fused deposition modeling.
Fig. 5 is a cross-sectional SEM image of a perfluorosulfonic acid composite produced by a hot press method.
FIG. 6 is a graph of displacement and bending angle for the hot pressing process for making perfluorosulfonic acid composites.
Fig. 7 is an overall structure diagram of the guiding device of the intervention type operation catheter based on the perfluorosulfonic acid composite material.
Figure 8 is a perfluorosulfonic acid composite made for use in an interventional surgical catheter guide.
FIG. 9 shows the regulation mode by applying an electric signal.
FIG. 10 is a diagram of the effect of the movement of the perfluorosulfonic acid composite material.
Detailed Description
The technical scheme of the invention is further explained in detail by combining the attached drawings:
example 1: additive manufacturing combined chemical platinized perfluorosulfonic acid composite material
1. Manufacture of perfluorosulfonic acid composite material by fused deposition modeling
The method comprises the following specific steps: manufacturing a Nafion precursor wire: manufacturing Nafion precursor wires with the diameters of 1.75mm, 2.0mm, 2.5mm and 2.85mm by using an extruder for Nafion precursor particles at the melting temperature of 230-250 ℃; printing a Nafion precursor film: setting the diameter of a nozzle of a 3D printer to be 0.4-0.6 mm, setting the temperature of the nozzle to be 275-305 ℃, setting the temperature of a hot bed to be 40-60 ℃, setting the printing speed to be 20-50 mm/s, and printing the manufactured Nafion precursor wire into a Nafion precursor film layer by utilizing a fused deposition molding technology; ③ hydrolyzing the Nafion precursor film: firstly, mixing potassium hydroxide, dimethyl sulfoxide and deionized water according to the mass fraction of 15%, 35% and 50% respectively to prepare hydrolysate; then placing the printed Nafion precursor membrane into hydrolysis liquid at 80 ℃ for hydrolysis, wherein the purpose of hydrolysis is to convert the Nafion precursor membrane without ion exchange capacity into the Nafion membrane with ion exchange capacity, and the effectiveness of manufacturing the perfluorosulfonic acid composite material is ensured; finally, taking the hydrolyzed Nafion membrane out of the hydrolysate, and washing the residual hydrolysate on the surface of the membrane with deionized water; fourthly, the perfluorosulfonic acid composite material is manufactured by a chemical plating method: firstly, soaking a hydrolyzed Nafion membrane in a platinum ammonia solution for 12 hours to enable platinum ammonia ions to be adsorbed in the Nafion membrane; then reducing platinum ions in the Nafion membrane into metal platinum particles by using sodium borohydride as a reducing agent, depositing the metal platinum particles on the surface of the Nafion membrane to form a metal electrode (figure 1) so as to obtain the perfluorosulfonic acid composite material; finally, the prepared perfluorosulfonic acid composite material is cut into strips and stored in deionized water.
2. Ion exchange Capacity test
Fig. 2 is a graph comparing the ion exchange capacity of hydrolyzed Nafion membrane to commercial membrane. The ion exchange capacity of the Nafion membrane which is printed by 3D printing is tested by an acid-base titration method and compared with that of a commercial membrane, and the test finds that the ion exchange capacity of the Nafion membrane which is manufactured by utilizing a fused deposition modeling technology is higher than that of the commercial membrane, which shows that the Nafion membrane which is manufactured by utilizing the fused deposition modeling technology has better ion exchange capacity.
3. Drive performance testing
The driving performance test of the perfluorosulfonic acid composite material was performed by using a test platform (allergy, zhao, dinghai, thomson, guogejie, daedong. IPMC artificial muscle material performance test apparatus CN 101813533A). The driving performance of the perfluorosulfonic acid composite material under a square wave voltage signal is measured, and the perfluorosulfonic acid composite material can generate an output displacement of 7.57mm (figure 3) and an output force of 10mN (figure 4) under a square wave voltage of 3.5V, so that the feasibility of manufacturing the perfluorosulfonic acid composite material by the method is verified.
Example 2: and (3) performing additive manufacturing to combine the flexible electrode and the hot-pressing perfluorinated sulfonic acid composite material.
1. Printing a Nafion substrate film
The method comprises the following specific steps: manufacturing a Nafion precursor wire: manufacturing Nafion precursor wires with the diameters of 1.75mm, 2.0mm, 2.5mm or 2.85mm by using an extruder to carry out Nafion precursor particles at the melting temperature of 230-250 ℃; printing a Nafion precursor film: setting the diameter of a nozzle of a 3D printer to be 0.4-0.6 mm, setting the temperature of the nozzle to be 275-305 ℃, setting the temperature of a hot bed to be 40-60 ℃, setting the printing speed to be 20-50 mm/s, and printing the manufactured Nafion precursor wire into a Nafion precursor film layer by utilizing a fused deposition molding technology; ③ hydrolyzing the Nafion precursor film: firstly, mixing potassium hydroxide, dimethyl sulfoxide and deionized water according to the mass fraction of 15%, 35% and 50% respectively to prepare hydrolysate; then placing the printed Nafion precursor membrane into hydrolysis liquid at 80 ℃ for hydrolysis, wherein the purpose of hydrolysis is to convert the Nafion precursor membrane without ion exchange capacity into the Nafion membrane with ion exchange capacity, and the effectiveness of manufacturing the perfluorosulfonic acid composite material is ensured; finally, taking the hydrolyzed Nafion membrane out of the hydrolysate, and washing the residual hydrolysate on the surface of the membrane with deionized water; acidifying the Nafion membrane: soaking the hydrolyzed Nafion base film in 10 wt.% of HNO3In the solution for 12h, K in the inside of a Nafion basement membrane is added+Is replaced by H+And stored in deionized water in preparation for the next hot pressing.
2. Manufacturing TPU-CNT flexible conductive film
The method comprises the following specific steps: adding 0.3g of multi-walled carbon nano-tube into a conical bottle; ② adding 20THF into a conical bottle; thirdly, magnetically stirring for 2 hours to fully dissolve the added particles into liquid mixed liquid; adding 1g of TPU particles, continuing to magnetically stir for 4 hours, and then carrying out ice bath ultrasound for 2 hours; vacuumizing to remove redundant bubbles in the mixed solution and reduce the porosity; sixthly, pouring the mixture into a glass dish, naturally volatilizing to form a film, and forming the film after about 12 hours to finish the manufacturing of the flexible conductive film.
3. Perfluorosulfonic acid composite material driver manufactured by hot pressing method
The method comprises the following specific steps: cutting a TPU-CNT flexible conductive film into sheets with the same size as a Nafion film, respectively placing the sheets on the upper side and the lower side of the Nafion film, and respectively coating a certain amount of concentrated Nafion solution between the Nafion film and the conductive film to serve as a transition layer so as to increase the bonding force between an electrode layer and a base film; putting the manufactured first step into a hot press, hot-pressing for 5min under the conditions that the temperature is 120 ℃ and the pre-pressure is 20N, and then cooling to room temperature to finish the hot-pressing manufacture of a Nafion base film and a TPU-CNT conductive film; thirdly, cutting the periphery of the composite film manufactured in the second step to obtain a perfluorosulfonic acid composite material sample, wherein the sample is a cross-sectional SEM image of the perfluorosulfonic acid composite material manufactured by a hot-pressing method as shown in FIG. 5, and the flexible conductive film and the Nafion film are obviously fused together from FIG. 5, so that the effectiveness of the perfluorosulfonic acid composite material is ensured; then the composite material is put into 0.5mol/L lithium chloride for testing, and FIG. 6 is a graph of the terminal displacement and the bending angle of the perfluorosulfonic acid composite material manufactured by a hot pressing method under the voltage output of sine 5V and 0.1 Hz.
Example 3: operating catheter guiding device based on perfluorosulfonic acid composite material
Fig. 7 is a general structure diagram of the guiding device of the surgical catheter based on the perfluorosulfonic acid composite material. The perfluorinated sulfonic acid composite material is attached to an electrode and embedded into a fixed guide head, a lead is connected with the electrode through a guide pipe, and the active bending function of the interventional operation guide pipe is realized by adjusting an electric signal.
As shown in FIG. 8, the column-shaped perfluorosulfonic acid composite material at the front end of the surgical catheter is manufactured by fused deposition modeling, and has the dimensions of 20mm × 1.0mm × 1.0mm (length × width × height). Because the electrode layer after chemical plating is an integral body, the bending motion of the columnar perfluorosulfonic acid composite material in different directions can be realized only by cutting the surface electrode of the columnar perfluorosulfonic acid composite material, and the surface electrode of the columnar perfluorosulfonic acid composite material is successfully separated by adopting a method of machining and cutting by a precision machine tool.
As shown in fig. 9, an electric signal applying control mode is adopted, and the columnar perfluorosulfonic acid composite material can realize bending motions of the columnar perfluorosulfonic acid composite material in 8 different directions by applying 8 different sets of voltage signal combinations to two pairs of electrodes.
As shown in fig. 10, which is a diagram of the motion effect of the perfluorosulfonic acid composite material, the complex bending motion of the columnar perfluorosulfonic acid composite material in a three-dimensional space can be realized by applying different voltage signals to a plurality of pairs of electrodes on the surface of the columnar perfluorosulfonic acid composite material to generate electric fields in different directions, so as to meet the functional requirements of the surgical catheter.
The present invention can be better understood from the above examples. Those skilled in the art will then readily appreciate that the specific specification parameters (perfluorosulfonic acid composite additive manufacturing techniques, columnar perfluorosulfonic acid composite dimensions, etc.), process conditions, and results described in the examples are merely illustrative of the present invention. The above description is only of the preferred embodiments of the present invention, and it should be noted that: it will be apparent to those skilled in the art that various modifications and adaptations can be made without departing from the principles of the invention and these are intended to be within the scope of the invention.

Claims (6)

1. A perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device are characterized by comprising the following steps:
step 1, performing extrusion molding on a Nafion precursor wire: extruding four Nafion precursor wires with the diameters of 1.75mm, 2.0mm, 2.5mm and 2.85mm by using an extruder at a proper melting temperature and a proper rotating speed;
step 2, printing a Nafion precursor film: printing the Nafion precursor wire by layers under proper printing parameters to form a Nafion precursor film by utilizing a fused deposition molding technology;
step 3, hydrolyzing a Nafion precursor membrane: putting the printed Nafion precursor membrane into hydrolysis liquid at the temperature of 80 ℃ for hydrolysis, and then washing with deionized water;
and 4, manufacturing a conductive electrode on the surface of the Nafion membrane by using a chemical plating method or a hot-press molding method, so as to realize the manufacturing of the perfluorosulfonic acid composite material.
2. The invention relates to a perfluorosulfonic acid composite material additive manufacturing method and a catheter active guiding device according to claim 1, wherein the invention comprises a method for manufacturing perfluorosulfonic acid composite material by fused deposition modeling technology, and the catheter guiding device comprises perfluorosulfonic acid composite material, electrodes, a fixed guide head, a lead and an interventional catheter.
3. The perfluorosulfonic acid composite material additive manufacturing method and the active guide device of the conduit according to claim 2, wherein the suitable melting temperature in step 1 is 230 to 250 ℃, the suitable printing parameters in step 2 are that the diameter of a printer nozzle is 0.4 to 0.6mm, the printing temperature is 275 to 305 ℃, the temperature of a hot bed is 40 to 60 ℃, and the printing speed is 20 to 50 mm/s.
4. The perfluorosulfonic acid composite material additive manufacturing method and the active guide device of the conduit according to claim 2, wherein the Nafion precursor particles, the Nafion precursor wires and the Nafion precursor membranes in step 1, step 2 and step 3 are Nafion precursors without ion exchange capacity.
5. The additive manufacturing method of perfluorosulfonic acid composite material and the active guiding device of the catheter according to claim 2, wherein the hydrolysate in step 3 is a mixture of potassium hydroxide, dimethyl sulfoxide and deionized water, and the mixture is 15%, 35% and 50% by mass respectively, in order to convert the Nafion precursor membrane without ion exchange capability into Nafion membrane with ion exchange capability.
6. The perfluorosulfonic acid composite material additive manufacturing method and the active guide device for the catheter according to claim 1, wherein: the active bending guide wire is connected with the electrode through the guide pipe, and the active bending function of the interventional operation guide pipe is realized by adjusting an electric signal.
CN202110614039.2A 2021-06-02 2021-06-02 Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device Pending CN113500758A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110614039.2A CN113500758A (en) 2021-06-02 2021-06-02 Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110614039.2A CN113500758A (en) 2021-06-02 2021-06-02 Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device

Publications (1)

Publication Number Publication Date
CN113500758A true CN113500758A (en) 2021-10-15

Family

ID=78008837

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110614039.2A Pending CN113500758A (en) 2021-06-02 2021-06-02 Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device

Country Status (1)

Country Link
CN (1) CN113500758A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929914A (en) * 2017-10-24 2018-04-20 南京航空航天大学 A kind of insertion type active catheter based on column IPMC electric actuations
CN110066485A (en) * 2019-04-20 2019-07-30 西北工业大学 A kind of ionic polymer metal composite material basement membrane 3D preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929914A (en) * 2017-10-24 2018-04-20 南京航空航天大学 A kind of insertion type active catheter based on column IPMC electric actuations
CN110066485A (en) * 2019-04-20 2019-07-30 西北工业大学 A kind of ionic polymer metal composite material basement membrane 3D preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CARRICO, JD (CARRICO, JAMES D.)，ET.AL: "Fused filament 3D printing of ionic polymer-metal composites (IPMCs)", 《SMART MATERIALS AND STRUCTURES》 *

Similar Documents

Publication Publication Date Title
US20090032394A1 (en) Ionic polymer devices and methods of fabricating the same
CN102372041B (en) IPMC (Ion-exchange polymer-metal composites) based gecko-simulating active driving sole and driving mode
CN110306210B (en) Electrochemical 3D printing device and method for metal-based composite material part
Yan et al. Progress and opportunities in additive manufacturing of electrically conductive polymer composites
CN103158226B (en) The preparation method of the complex of metal and plastics and complex
KR101015180B1 (en) Polymer actuator, catheter comprising the same and its preparation method
CN103590076A (en) Laser-reinforced electrodeposition rapid-prototyping processing apparatus and method
CN112103529A (en) Metal bipolar plate of fuel cell and preparation method thereof
CN110359065B (en) Jet electrodeposition nozzle and method for manufacturing seamless metal pipe by using same
CN112522766B (en) Suction-combined electrochemical micro-additive preparation method and device
CN110053257A (en) A kind of gel-like bionics artificial thews 3D printing device and preparation method
CN108381903A (en) A kind of flexible circuit 3 D-printing method that macromolecule liquid metal prints altogether
CN110284160A (en) A kind of photoinduction electrochemical metal 3D printing device and method
CN113500758A (en) Perfluorosulfonic acid composite material additive manufacturing method and catheter active guiding device
CN111270349B (en) Preparation method of graphene oxide fiber and three-dimensional scaffold based on microfluid spinning
CN110656358A (en) Micron-grade pure aluminum 3D printing equipment and method
CN112779567B (en) Micro machining tool preparation device and method and in-situ material increase and reduction manufacturing method
CN203593801U (en) Laser strengthening electro-deposition rapid prototyping processing device
CN113274174A (en) Self-rolling intravascular stent forming system and forming method
CN111312529A (en) Meniscus-constrained electrodeposition polypyrrole planar supercapacitor 3D printing device and method
CN101143950A (en) Preparation method for ionic polymer metal composite material
CN111504519B (en) Flexible cable type touch sensor
CN210126284U (en) Quick 3D printing device of face shaping based on electrostatic spinning method
CN104466103B (en) PEO-coated hollow Sn-Ni alloy nanowire array, and preparation method and application of PEO-coated hollow Sn-Ni alloy nanowire array
CN113134968A (en) Flexible electronic component 3D printing device and method based on electrodeposition and double nozzles

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20211015