CN113457003A - Multi-frequency vibration ultrasonic leading-in device for large-depth transvaginal mucosa - Google Patents
Multi-frequency vibration ultrasonic leading-in device for large-depth transvaginal mucosa Download PDFInfo
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- CN113457003A CN113457003A CN202110887333.0A CN202110887333A CN113457003A CN 113457003 A CN113457003 A CN 113457003A CN 202110887333 A CN202110887333 A CN 202110887333A CN 113457003 A CN113457003 A CN 113457003A
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- 238000002604 ultrasonography Methods 0.000 claims description 23
- 239000010410 layer Substances 0.000 claims description 10
- 210000001519 tissue Anatomy 0.000 claims description 7
- 210000004876 tela submucosa Anatomy 0.000 claims description 4
- 235000012431 wafers Nutrition 0.000 claims description 4
- 239000002344 surface layer Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 7
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 230000002708 enhancing effect Effects 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 20
- 229940079593 drug Drugs 0.000 description 5
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- 230000003796 beauty Effects 0.000 description 3
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- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
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- 230000000474 nursing effect Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/14—Female reproductive, genital organs
- A61M2210/1475—Vagina
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Transducers For Ultrasonic Waves (AREA)
Abstract
The invention discloses a transvaginal large-depth multi-frequency ultrasonic leading-in device which comprises a clock unit, a low-frequency driving unit, a medium-frequency driving unit, a high-frequency driving unit and a transvaginal ultrasonic probe. The ultrasonic probe comprises two high-frequency piezoelectric vibrators, two medium-frequency piezoelectric vibrators and a low-frequency piezoelectric vibrator, wherein the five piezoelectric vibrators are arranged into a circular arc shape at a certain interval to form a multi-array source ultrasonic array, and a high-frequency ultrasonic focus, a medium-frequency ultrasonic focus and a low-frequency ultrasonic focus are sequentially focused on the circular arc from the circular arc on a central line of the circular arc. The large-depth multi-frequency ultrasonic introduction method is beneficial to enhancing the absorption effect of the care solution of the vaginal mucosa.
Description
Technical Field
The invention relates to the technical field of beauty treatment and body beautification devices, in particular to a special care solution and medicine absorption enhancing device for female private parts.
Background
With the continuous improvement of living standard of people, people not only have higher and higher requirements for external beauty, but also pay more attention to the inherent health of women. However, the female reproductive system will also age with age, and besides various gynecological diseases, it will also affect the beauty of women and the harmony of the couple life, and directly affect the quality of life and the harmony of the family. The reasons for the aging and relaxation of the female reproductive system are: 1. collagen in the dermis runs off with age; 2. birth, sexual life cause elastic fiber breakage; 3. the ovarian secretion of estrogen is reduced. Various secret treatment methods are diversified, mainly including various photoelectric techniques, injection techniques, line carving techniques, and the like, and local smearing medicines. After the treatment by the photoelectric technology, the local part is dry, the medicine is difficult to absorb when being smeared on the local part, and the treatment effect of the care solution and the medicine is very little. Because there is connective tissue with rich blood vessels under the vaginal mucosa, the nursing liquid and the medicine penetrate into the submucosal tissue through the mucosa, and the medicine can be quickly absorbed by the body under the drive of active blood circulation. Because the medicine is naturally absorbed, the medicine has higher safety and effectiveness, and can reduce a plurality of adverse reactions. Therefore, in recent years, many drugs for percutaneous absorption and physical methods and devices for promoting skin absorption have appeared. However, no device for promoting drug absorption in organs in vivo has emerged. Therefore, there is a need for a vaginal device that facilitates the absorption of solutions and drugs.
The invention aims to provide a device which utilizes ultrasonic waves to vibrate a medium and gas molecules and bubbles in cells, and then the medium and the gas molecules and the bubbles are broken to form gaps, so that the permeation and absorption effects of a care solution are enhanced.
The application No. CN200710001842.9 discloses an ultrasonic medicine introducing method and an apparatus thereof. The invention adopts a mode of combining low-frequency ultrasound and high-frequency signals to act on a target area to promote the introduction of a medicament into the target area, wherein the low-frequency ultrasonic signals of the invention are generated by a non-focusing type low-frequency oscillator, and the high-frequency ultrasonic signals are generated by a focusing type high-frequency oscillator; the application No. CN201210264952.5 discloses an ultrasonic and ion-introduced device for introducing transdermal drugs or cosmetics. The invention adopts low-frequency ultrasonic signals and high-frequency ultrasonic signals to act on the surface of the skin to promote the introduction of the medicine, the low-frequency ultrasonic signals and the high-frequency ultrasonic signals are generated by piezoelectric ceramics or piezoelectric crystals, the device of the invention has the effect of promoting the introduction of the medicine, but the low-frequency ultrasonic signals and the high-frequency ultrasonic signals are not focused, the invention utilizes the common action of the low-frequency ultrasonic signals and the high-frequency ultrasonic signals to loosen the stratum corneum of the skin, enhance the permeability and further promote the introduction of the medicine, and although the method has a certain effect on the introduction of the medicine, the target region of action is shallow, and the medicine cannot act on the deeper target region to promote the introduction of the medicine into the deeper target region.
Disclosure of Invention
To overcome the above disadvantages, the present invention provides a transvaginal large depth, multi-frequency ultrasound introduction device comprising:
the transvaginal large-depth multi-frequency ultrasonic leading-in device sequentially comprises: the device comprises a clock unit, a low-frequency driver, a medium-frequency driver, a high-frequency driver and a transvaginal ultrasound guide probe;
the clock unit is used for synchronizing the low-frequency driver, the intermediate-frequency driver and the high-frequency driver; the low-frequency driver generates low-frequency sinusoidal voltage to drive the ultrasonic probe to emit low-frequency ultrasonic waves; the intermediate frequency driver generates intermediate frequency sinusoidal voltage to drive the ultrasonic probe to transmit intermediate frequency ultrasonic waves; the high-frequency driver generates high-frequency sinusoidal voltage to drive the ultrasonic probe to emit high-frequency ultrasonic waves; the transvaginal ultrasound probes have different depths of focus.
Preferably, the frequency of the low-frequency ultrasonic wave is 250 kHz.
Preferably, the frequency of the medium-frequency ultrasonic waves is 3-10 MHz.
Preferably, the frequency of the high-frequency ultrasonic waves is 15-30 MHz.
The oscillator for transmitting ultrasonic waves is a multi-curvature focusing piezoelectric wafer, and the mirror symmetry piezoelectric wafers have the same curvature radius.
Each piezoelectric unit of the multi-curvature piezoelectric unit is a cylindrical piezoelectric focusing unit capable of generating a linear focusing sound field.
The focusing depths of the multi-curvature piezoelectric units are different in sequence, the outermost mirror symmetry piezoelectric unit focuses on the surface layer of a mucosa, the middle mirror symmetry piezoelectric unit focuses on the submucosa, and after the central piezoelectric unit focuses on the submucosa, three discrete focuses form a focusing range with large depth.
The outermost mirror image piezoelectric unit is a high-frequency piezoelectric vibrator, the dominant frequency is dozens of MHz, and high-frequency ultrasonic waves can be transmitted to the tissue shallow layer; the middle-layer mirror symmetry piezoelectric unit is a medium-frequency piezoelectric vibrator, the dominant frequency is several MHz, and the middle-layer mirror symmetry piezoelectric unit can transmit medium-frequency ultrasonic waves to the middle layer of the tissue; the central piezoelectric unit is a low-frequency piezoelectric vibrator, the main frequency is dozens of kHz, and low-frequency ultrasonic waves can be emitted to the deep layer of the tissue.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only embodiments of the present patent, and it is obvious for those skilled in the art to obtain other drawings according to the provided drawings without creative efforts.
FIG. 1 is a schematic diagram showing the components of a transvaginal large depth, multi-frequency ultrasound introduction device in an embodiment of the present application;
fig. 2 shows a schematic diagram of a cross-sectional structure of a large-depth multi-frequency ultrasound probe and a schematic diagram of different-depth focusing in an embodiment of the present application.
FIG. 3 shows a schematic structural view of a transvaginal large depth, multi-frequency ultrasound introduction probe in an embodiment of the present application;
Detailed Description
A transvaginal, high-depth, multi-frequency ultrasound introduction device, as shown in fig. 1, includes a clock unit 1, a low frequency driver 2, a medium frequency driver 3, a high frequency driver 4, and a transvaginal ultrasound introduction probe 5. The transvaginal ultrasound introduction probe 5 is generally in a cylindrical or cylinder-like structure, the outer diameter of the transvaginal ultrasound introduction probe is 12mm, the transvaginal ultrasound introduction probe 5 is made of ABS (acrylonitrile butadiene styrene), and the transvaginal ultrasound introduction probe is respectively connected to the low-frequency driver 2, the medium-frequency driver 3 and the high-frequency driver 4 through 3 cables.
As shown in FIG. 2, the transvaginal ultrasound probe 5 is composed of 5 piezoelectric vibrators arranged in sequence as a high-frequency piezoelectric vibrator 7-1, a medium-frequency piezoelectric vibrator 6-1, a low-frequency piezoelectric vibrator 5, a medium-frequency piezoelectric vibrator 6-2 and a high-frequency piezoelectric vibrator 7-2. The high-frequency piezoelectric vibrators 7-1 and 7-2 have the same curvature radius; the medium-frequency piezoelectric vibrators 6-1 and 6-2 have the same curvature radius; the low, medium and high frequency piezoelectric vibrators have different curvatures.
Each piezoelectric vibrator is spaced 0.2mm apart.
The low-frequency piezoelectric vibrator 5 is made of a ceramic sheet.
The medium-frequency piezoelectric vibrators 6-1 and 6-2 are made of ceramic plates.
The materials of the high-frequency piezoelectric vibrators 7-1 and 7-2 are composite material sheets.
The probe shell groove 11 is made of plastic, the back material 9 is coated in the probe groove, the material is epoxy resin, and the thickness is 2 mm. After curing at normal temperature, 5 piezoelectric vibrators are sequentially arranged in the probe groove at an interval of 0.2 mm. Rubber 10 is added and encapsulated.
The low-frequency piezoelectric vibrator 5-1, in this embodiment, the main frequency of the piezoelectric vibrator is 250kHz, and the low-frequency piezoelectric vibrator is connected to the low-frequency driver 2 through a coaxial cable. The low frequency driver 2 generates a low frequency sinusoidal drive signal, in this embodiment at a drive frequency of 250 kHz. The low-frequency sine driving signal is pressurized at two poles of the low-frequency piezoelectric vibrator 5-1 to generate low-frequency ultrasonic waves. The low-frequency piezoelectric vibrator 5-1 forms cylindrical focusing, and the focal length is 20 mm.
The medium-frequency piezoelectric vibrators 6-1 and 6-2 are respectively connected with the medium-frequency driver 3 through coaxial cables, wherein the main frequency of the medium-frequency piezoelectric vibrator is 5 MHz. The intermediate frequency driver 3 generates an intermediate frequency sinusoidal drive signal, in this embodiment at a drive frequency of 5 MHz. The medium-frequency sinusoidal driving signal is pressed on two poles of medium-frequency piezoelectric vibrators 6-1 and 6-2 to generate medium-frequency ultrasonic waves. The medium-frequency piezoelectric vibrators 6-1 and 6-2 form cylindrical focusing, and the focal length is 10 mm.
High-frequency piezoelectric vibrators 7-1 and 7-2, wherein the main frequency of the piezoelectric vibrator is 20MHz in the embodiment, and the high-frequency piezoelectric vibrators are respectively connected with the high-frequency driver 4 through coaxial cables. The high frequency driver 4 generates a high frequency sinusoidal drive signal, in this embodiment at a drive frequency of 20 MHz. The high-frequency sine driving signal is pressurized at two poles of the high-frequency piezoelectric vibrators 7-1 and 7-2 to generate high-frequency ultrasonic waves. The high-frequency piezoelectric vibrators 7-1 and 7-2 form cylindrical focusing, and the focal length is 5 mm.
High-frequency piezoelectric vibrators 7-1 and 7-2, wherein the main frequency of the piezoelectric vibrator is 20MHz in the embodiment, and the high-frequency piezoelectric vibrators are respectively connected with the high-frequency driver 4 through coaxial cables. The high frequency driver 4 generates a high frequency sinusoidal drive signal, in this embodiment at a drive frequency of 20 MHz. The high-frequency sine driving signal is pressurized at two poles of the high-frequency piezoelectric vibrators 7-1 and 7-2 to generate high-frequency ultrasonic waves. The high-frequency piezoelectric vibrators 7-1 and 7-2 form cylindrical focusing, and the focal length is 5 mm.
Claims (6)
1. The transvaginal large-depth multi-frequency ultrasound introduction device is characterized by sequentially comprising: the device comprises a clock unit, a low-frequency driver, a medium-frequency driver, a high-frequency driver and a transvaginal ultrasound guide probe; the clock unit is used for synchronizing the low-frequency driver, the medium-frequency driver and the high-frequency driver; the low-frequency driver generates low-frequency sinusoidal voltage to drive the ultrasonic probe to emit low-frequency ultrasonic waves; the intermediate frequency driver generates intermediate frequency sinusoidal voltage to drive the ultrasonic probe to transmit intermediate frequency ultrasonic waves; the high-frequency driver generates high-frequency sinusoidal voltage to drive the ultrasonic probe to emit high-frequency ultrasonic waves; the transvaginal ultrasound probes have different depths of focus.
2. The transvaginal large-depth multi-frequency ultrasound introduction device as claimed in claim 1, wherein two high-frequency piezoelectric vibrators, two medium-frequency piezoelectric vibrators and one low-frequency piezoelectric vibrator are arranged in the transvaginal ultrasound introduction probe;
the low-frequency ultrasonic wave is in dozens of kHz;
the medium frequency ultrasonic waves are at several MHz;
the high-frequency ultrasonic waves are at several tens of MHz.
3. The transvaginal, high-depth, multi-frequency ultrasound introduction device of claim 1, wherein the ultrasound emitting transducer is a multi-curvature focused piezoelectric wafer, the mirror symmetric piezoelectric wafers having the same radius of curvature.
4. The transvaginal large depth, multi-frequency ultrasound introduction device of claim 3, wherein each of said multi-curvature piezoelectric elements is a cylindrical piezoelectric focusing element capable of generating a linearly focused acoustic field.
5. The transvaginal large-depth multi-frequency ultrasound introduction device according to claim 4, wherein the multi-curvature piezoelectric elements have sequentially different depths of focus, the outermost mirror-symmetric piezoelectric element is focused on the surface layer of the mucosa, the middle mirror-symmetric piezoelectric element is focused on the submucosa, and after the central piezoelectric element is focused on the submucosa, three discrete foci form a large-depth focus range.
6. The transvaginal multifrequency ultrasonic introduction device of claim 5, wherein the outermost mirror image piezoelectric unit is a high frequency piezoelectric vibrator with a dominant frequency of tens of MHz capable of emitting high frequency ultrasonic waves to the tissue superficial layer; the middle-layer mirror symmetry piezoelectric unit is a medium-frequency piezoelectric vibrator, the dominant frequency is several MHz, and the middle-layer mirror symmetry piezoelectric unit can transmit medium-frequency ultrasonic waves to the middle layer of the tissue; the central piezoelectric unit is a low-frequency piezoelectric vibrator, the main frequency is dozens of kHz, and low-frequency ultrasonic waves can be emitted to the deep layer of the tissue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110887333.0A CN113457003A (en) | 2021-08-05 | 2021-08-05 | Multi-frequency vibration ultrasonic leading-in device for large-depth transvaginal mucosa |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110887333.0A CN113457003A (en) | 2021-08-05 | 2021-08-05 | Multi-frequency vibration ultrasonic leading-in device for large-depth transvaginal mucosa |
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| CN113457003A true CN113457003A (en) | 2021-10-01 |
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| CN202110887333.0A Pending CN113457003A (en) | 2021-08-05 | 2021-08-05 | Multi-frequency vibration ultrasonic leading-in device for large-depth transvaginal mucosa |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588526A (en) * | 2022-03-30 | 2022-06-07 | 中南大学 | Double-frequency ultrasonic microneedle array device |
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| CN105392529A (en) * | 2013-03-28 | 2016-03-09 | 华盛顿大学商业化中心 | Focused ultrasound apparatus and methods of use |
| CN205235196U (en) * | 2014-03-18 | 2016-05-18 | 海罗尼克株式会社 | High strength focus supersound operation device |
| WO2020026254A1 (en) * | 2018-08-02 | 2020-02-06 | Sofwave Medical Ltd. | Devices and methods for vaginal treatments |
| WO2020112688A1 (en) * | 2018-11-30 | 2020-06-04 | Ulthera, Inc. | Systems and methods for enhancing efficacy of ultrasound treatment |
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2021
- 2021-08-05 CN CN202110887333.0A patent/CN113457003A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247661A (en) * | 2010-05-17 | 2011-11-23 | 高春平 | Complex frequency focused ultrasound non-invasive fat dissolving method and device |
| CN105392529A (en) * | 2013-03-28 | 2016-03-09 | 华盛顿大学商业化中心 | Focused ultrasound apparatus and methods of use |
| CN205235196U (en) * | 2014-03-18 | 2016-05-18 | 海罗尼克株式会社 | High strength focus supersound operation device |
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| CN105105790A (en) * | 2015-09-02 | 2015-12-02 | 上海爱声生物医疗科技有限公司 | Uterus-passing oviduct ultrasonic detection method, uterus-passing oviduct ultrasonicdiagnosis device and transducer |
| WO2020026254A1 (en) * | 2018-08-02 | 2020-02-06 | Sofwave Medical Ltd. | Devices and methods for vaginal treatments |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588526A (en) * | 2022-03-30 | 2022-06-07 | 中南大学 | Double-frequency ultrasonic microneedle array device |
| CN114588526B (en) * | 2022-03-30 | 2023-08-22 | 中南大学 | Dual-frenquency supersound microneedle array device |
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