CN113403341A - 一种基于tale组装的线粒体dna编辑系统 - Google Patents
一种基于tale组装的线粒体dna编辑系统 Download PDFInfo
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Abstract
本发明属于基因编辑技术领域，公开了一种基于TALE组装的线粒体DNA编辑系统。该编辑系统，包括RVD文库、线粒体定位骨架载体、细胞核定位骨架载体，RVD文库包含至少192个RVD模块，包括：160个双RVD模块、16个单RVD模块及16个半RVD模块。该编辑系统可显著提高TALE模块组装效率，显著降低TALE模块组装成本和时间；该发明使用的组装方法操作简单，适合推广应用；通过该方法可快速高效实现线粒体DNA编辑，并用于制作各种动物模型，以模拟人类线粒体DNA突变导致的疾病；可潜在应用于线粒体DNA突变疾病基因治疗。
Description
技术领域
本发明属于基因编辑技术领域，尤其是一种基于TALE组装的线粒体DNA编辑系统。
背景技术
转录激活样效应因子(TALE)是二代基因编辑工具的核心模块，其主要由若干34个氨基酸的重复单元构成，并利用12和13位的氨基酸构成的两个重复可变残基(RVD,repeat-variable di-residue)特异性识别DNA序列。已报道多种方法可用于TALE模块的组装，但这些方法大都繁琐、耗时、费力且代价高昂，因此如何高效组装定制TALE成为其推广和应用的难点。
线粒体疾病是以线粒体功能异常为显著特征的一类重大疾病。线粒体疾病常由细胞核基因突变和线粒体DNA突变引起，且线粒体DNA突变通常引起更严重的人类疾病，如线粒体脑肌病，共济失调等。采用ZFN和TALEN加上线粒体定位信号(MTS)，可以实现对突变的线粒体DNA进行切割，导致发生双链断裂的线粒体DNA被降解掉，但是该方法不能用于构建线粒体DNA突变动物模型，以及用于线粒体DNA突变修复，具有很大局限性。由于CRISPR/Cas9的sgRNA无法进入线粒体，导致该技术无法用于线粒体DNA编辑。目前，细菌毒素蛋白的DddA功能域即DddAtox具有双链DNA脱氨基酶活性，通过和TALE相连形成胞嘧啶碱基编辑器(DdCBE)，可以实现线粒体中定点C/G到T/A的突变。因此，通过构建RVD文库及线粒体DNA编辑工具载体，形成了一种基于TALE组装的线粒体DNA编辑系统。
发明内容
本发明的目的是针对现有技术存在的问题，提供一种基于TALE组装的线粒体DNA编辑系统。
本发明另一个目的是提供采用该线粒体DNA编辑系统的编辑方法。
本发明再有一个目的是提供该编辑方法在制备模拟人类疾病的线粒体DNA突变动物模型中的应用。
本发明的目的通过下列技术方案实现的：
一种基于TALE组装的线粒体DNA编辑系统，包括RVD文库、线粒体定位骨架载体、细胞核定位骨架载体，RVD文库包含至少192个RVD模块，包括：160个双RVD模块、16个单RVD模块及16个半RVD模块。
所述的双RVD模块识别2个DNA碱基，从位置1到10，共有10个位置顺序，可依次对应识别DNA 5’端到3’端的第1-20位置的核苷酸，每个位置上有16种组合，因此共有160个双RVD模块；单RVD模块识别1个DNA碱基，从位置7-10，共有4个位置顺序，可依次对应识别DNA5’端到3’端的第13、15、17和19位置的核苷酸，每个位置上有4种可能，因此共有16个单RVD模块；半RVD模块识别1个DNA碱基，从位置8-11，共有4个位置顺序，可依次对应识别DNA5’端到3’端的第14、16、18、20和21位置的核苷酸，每个位置上有4种可能，因此共有16个半RVD模块。
进一步的，所述的不同位置RVD模块的DNA序列两端含有Bsa I酶切位点，用以产生4个不同碱基序列的粘性末端，以决定前后RVD模块连接的顺序。
进一步的，RVD文库中的每个载体上含有四环素抗性元件用于克隆筛选。
所述的线粒体DNA编辑系统，其中：RVD文库中不同位置的双、单和半RVD载体序列，其在Bsa I限制性内切酶切割后产生具有位置特异性的粘性末端序列，可使RVD序列按位置顺序自动排列组装，可以组装识别14-21个碱基TALE。
所述的线粒体DNA编辑系统，其中：160个双RVD的氨基酸序列如Seq ID NO：1-160所示；16个单RVD的氨基酸序列如Seq ID NO：161-176所示；16个半RVD的氨基酸序列如SeqID NO：177-192所示；160个双RVD的核苷酸序列如Seq ID NO：203-362所示；16个单RVD的核苷酸序列如Seq ID NO：363-378所示；16个半RVD的核苷酸序列如Seq ID NO：379-394所示。
注：下文中RVD文库DNA序列5’端和3’端连接的大写字母的碱基为Bsa I识别位点及间隔序列，非RVD模块DNA序列本身(本身为小写字母的碱基)。
所述的线粒体DNA编辑系统，其中：所述线粒体定位骨架载体的主要元件从5’端到3’端依次为线粒体定位信号(MTS)、ccdb毒素基因、half DddAtox、尿嘧啶糖基化酶抑制基因(UGI)、氨卞青霉素抗性元件；4个线粒体定位骨架载体其核苷酸序列如Seq ID NO：193-196所示。
所述的线粒体DNA编辑系统，其中，所述细胞核定位骨架的主要元件从5’端到3’端依次为细胞核定位信号(NLS)、ccdb毒素基因、half DddAtox、尿嘧啶糖基化酶抑制基因(UGI)、氨卞青霉素抗性元件；4个细胞核定位骨架其核苷酸序列如Seq ID NO：197-200所示。
进一步的，在DddAtox第1333氨基酸位置和第1397氨基酸位置分割产生的4种halfDddAtox，分别给half DddAtox融合线粒体定位信号(MTS)或核定位信号(NLS)，因此有4个线粒体定位骨架载体和4个细胞核定位骨架载体。
进一步的，每个载体上的Bsa I酶切位点间含有ccdb毒素基因，两端的Bsa I酶切产生不同的粘性末端，用于特异性连接1号位置的双RVD模块和8-11号位置的半RVD模块。
进一步的，每个载体上在half DddAtox之后含有1个尿嘧啶糖基化酶抑制基因UGI，用于提高线粒体DNA定点的C/G到T/A的突变效率。
一种上述基于TALE组装的线粒体DNA编辑系统的编辑方法，包括以下步骤：
步骤1、根据所要编辑位点的DNA序列，设计TALE序列，选择权利要求1所述的RVD模块与骨架载体，通过Golden Gate克隆法一步完成载体组装，形成胞嘧啶碱基编辑器(DdCBE)；组装完成的DdCBE载体经过转化DH5α感受态、单克隆PCR验证、Sanger测序等步骤后，可获得正确组装的DdCBE载体；
步骤2、将正确组装的MTS-DdCBE转染所要编辑物种的细胞，或NLS-DdCBE与含有编辑位点的T载体共同转染HEK293FT细胞，通过Sanger测序或高通量测序检测DdCBE编辑效率，筛选对线粒体DNA或T载体编辑效果最好的DdCBE组合；
步骤3、将编辑效果最好的DdCBE进行体外转录，注射1细胞期受精卵，然后将胚胎移植到受体动物输卵管，或通过体外发育获得F0代动物；通过Sanger测序及高通量测序检测F0代的编辑效率，筛选高编辑效率的F0代动物；
步骤4、将高编辑效率的雌性F0代动物与野生型雄性动物交配，获得的F1代动物通过Sanger测序及高通量测序检测编辑效率，高编辑效率的动物则存在模拟人类疾病的可能。
所述的编辑方法在制备模拟人类疾病的线粒体DNA突变动物模型中的应用。
为了实现TALE的高效组装，相对于Kim Y等报道的含有424个载体的RVD文库(NatBiotechnol.2013Mar；31(3):251-8.)和Zhang等报道的含有256个载体的RVD文库(PLoSOne.2013Jun 20；8(6):e66459.)，本发明构建含有192个载体的RVD文库。相比于STAR方法需要几天时间(Methods Mol Biol.2018；1772:477-490.)，本发明只需要通过10轮的10分钟酶切加10分钟连接，共计4小时的反应就能完成组装。连接产物转化后经过12小时的菌落培养，进行PCR菌落鉴定并送测sanger测序，36小时之内就能得到经测序验证的正确载体。此外，相对于Mok BY等报道的TALE-DddAtox(Nature.2020Jul；583(7817):631-637.)，本发明开发的一种基于TALE组装的线粒体DNA编辑系统，精简了骨架载体的数量，可以定制化快速构建线粒体DNA编辑载体，成功在动物上实现了线粒体DNA编辑。
本发明可以获得有益效果如下：
1)本发明精简了RVD模块文库，显著提高TALE组装效率。
2)本发明提出的TALE组装方法简化流程，操作简单，适合推广应用。
3)本发明提出的TALE组装方法在36小时之内可以获得经测序验证的正确载体。
4)本发明提出的TALE组装方法末位不受T碱基限制，可以是任意碱基。
5)本发明构建了线粒体定位骨架载体和细胞核定位骨架载体，对于有稳定细胞系的物种，直接将TALE连接到线粒体定位骨架载体，然后转染细胞系，筛选高效DdCBE对；对于没有稳定细胞系的物种，可以采用将TALE连接到细胞核定位骨架载体，然后和含有编辑位点的T载体共同转染HEK293FT细胞，筛选出高效的DdCBE对。高效的DdCBE对可用于制作线粒体DNA突变动物模型，以模拟人类疾病，并可潜在应用于人类线粒体DNA突变疾病的治疗。
附图说明
图1线粒体定位骨架载体
图1带有线粒体定位信号(MTS)的不同分割类型的DddAtox，载体携带ccdb和UGI元件，ccdb位于两个Bsa I酶切位点之间，载体上带有氨卞青霉素抗性元件。
图2细胞核定位骨架载体。
图2带有细胞核定位信号(NLS)的不同分割类型的DddAtox，载体携带ccdb和UGI元件，ccdb位于两个Bsa I酶切位点之间，载体上带有氨卞青霉素抗性元件
图3RVD文库示意图。
图3RVD文库载体示意图，左侧数字代表RVD的位置，双RVD模块位于1-10位，共160个载体；单RVD模块位于7-10位，共16个载体；半RVD模块位于8-11位，共16个载体。RVD两侧的DNA序列为Bsa I切割所产生的粘性末端DNA序列，每个RVD载体均带有四环素抗性。
图4人线粒体DNA G3733突变致病位点的保守性分析。
图4中箭头所指位置为编辑位点，灰色字母表示TALE识别位点，编辑位点的基因为nd1。G3733为人类线粒体DNA中的位置，G4247为斑马鱼线粒体DNA中的位置。
图5人线粒体DNA G8363突变致病位点的保守性分析。
图5中箭头所指位置为编辑位点，灰色字母表示TALE识别位点，编辑位点的基因为trnk。G8363为人类线粒体DNA中的位置，G8892为斑马鱼线粒体DNA中的位置。
图6DdCBE在T载体上编辑效果分析
图6左采用高通量测序分别分析T载体上G4247的编辑效率，图6右采用Sanger测序分析斑马鱼混合胚胎上G8892的编辑效率所用，DdCBE组合及方向如图X轴所示。
图7F0代斑马鱼线粒体DNA上G4247位点编辑效率分析。
图7左采用Sanger测序分析DdCBE在G4247位点的编辑效果，编辑位点采用箭头标出；图7右表示高通量测序分析DdCBE在F0代斑马鱼中G4247位点的编辑效率。
图8F0代斑马鱼线粒体DNA上G8892位点编辑效率分析。
图8左采用Sanger测序分析DdCBE在G8892位点的编辑效果，编辑位点采用箭头标出；图8右表示高通量测序分析DdCBE在F0代斑马鱼中G8892位点的编辑效率。
图9携带线粒体DNA突变的斑马鱼体型及运动轨迹分析。
图9左120日龄的线粒体DNA突变斑马鱼与野生型斑马鱼体型大小分析；图9右线粒体DNA突变斑马鱼与野生型斑马鱼运动轨迹分析。
图10携带线粒体DNA突变的斑马鱼运动能力分析。
图10左120日龄的线粒体DNA突变斑马鱼与野生型斑马鱼运动速度分析；图10右。120日龄的线粒体DNA突变斑马鱼与野生型斑马鱼运动距离分析。
图11携带线粒体DNA突变的斑马鱼线粒体结构分析。
采用透射电镜分析线粒体DNA突变斑马鱼与野生型斑马鱼肌肉组织中线粒体结构。
具体实施方式
以下通过实施例对本发明做详细说明，借此对如何应用本发明实现线粒体DNA的基因编辑充分理解并据以实施。
下面结合附图对本发明进一步说明。本发明提供一种基于高效组装TALE的线粒体DNA编辑系统。
其中，提供一种高效组装TALE的方法，该方法的使用需要一个含有192个载体的RVD文库，包括：160个双RVD模块、16个单RVD模块及16个半RVD模块。
其中，还提供一种匹配于RVD文库的线粒体DNA编辑系统，该系统包括：8个载体。
在本系统中，组装TALE的RVD文库及匹配于RVD文库的线粒体DNA编辑系统，通过在一个体系中的反应，可实现在36小时内完成组装。该系统高效且价格低廉，操作简单且易于推广，这是在本课题组长期研究和实践中所优化出来的重要创新。
实施例1
利用基于高效组装TALE的线粒体DNA编辑系统，实现斑马鱼线粒体DNA突变模型的构建，并模拟人类疾病模型。
(一)RVD模块的选择及TALE的组装
选择人类线粒体DNA(参考序列版本：NC_012920.1)上G3733和G8363的C/T to G/A的致病突变位点，根据保守性分析筛选相应的靶位点(图4和图5)。针对这2个致病突变位点，设计对应斑马鱼上G4247和G8892位点(参考序列版本:NC_002333.2)。根据DNA序列，在本发明RVD文库中选择相应位置的RVD，如：DNA序列的第1和第2个碱基为GT，选择RVD文库中1号位置识别GT序列的RVD模块；当第3和第4个碱基为AG时，则选择RVD文库中2号位置识别AG序列的RVD模块，并依次类推。当DNA序列长度为奇数时，选择识别最后一个碱基对应的半RVD模块。而当序列长度为偶数时，选择识别倒数第二个碱基对应的单RVD模块，并选择识别最后一个碱基对应的半RVD模块。
这里以G4247为例，如奇数个碱基序列G4247A-R15：AATAGAATAAGTCCT则挑选RVD模块为7个双RVD和1个半RVD；其RVD组合如下：AA1、TA2、GA3、AT4、AA5、GT6、CC7和hT8。如偶数个碱基序列G4247A-L16：GTAGCGCAAACAATTT则挑选RVD模块为7个双RVD和1个单RVD和1个半RVD；其RVD组合如下：GT1、AG2、CG3、CA4、AA5、CA6、AT7、pC8和hT9。
将线粒体定位的骨架载体或细胞核定位的骨架载体(图1和2)，与选择好的RVD模块，其中RVD模块数量与TALE识别的DNA序列长度相关，并按照表1的体系添加到PCR管中，试剂来源在表中给出。在PCR仪中使用下述反应条件进行反应：37℃ 10min,16℃ 10min，10个循环；50℃ 5min；80℃ 5min；4℃ hold。由于Bsa I内切酶和T4连接酶的存在，在一个反应体系内可同时实现载体的酶切和连接。
表1：TALE文库组装的反应体系
| 成分 | 体积(μL) |
| RVD模块(50ng/μL) | 0.5each |
| 骨架载体(100ng/μL) | 1 |
| T4 Buffer(NEB) | 1 |
| T4 DNAligase(NEB) | 0.5 |
| Bsa I(NEB) | 0.5 |
| 加H<sub>2</sub>O补充至 | 10 |
在反应结束后，将产物转化DH5α并采用含有氨卞青霉素的固体LB培养板进行筛选，之后挑取单克隆并使用下述引物进行PCR鉴定，引物序列如Seq ID NO:201-202所示。根据RVD数量，判断阳性的克隆，如16个RVD大小应为1759bp，15个RVD大小应为1657bp。之后，使用上述引物进行正反测序，序列正确的阳性克隆提取质粒用于后续实验。
(二)在体外细胞中进行DdCBE编辑效率的检测
针对没有可用细胞系的动物斑马鱼，可先将图4和5中所示的编辑位点的序列克隆到T载体上。待HEK293FT细胞密度达到70-90％时，提前2小时换液，细胞计数后，取105个细胞用于细胞电转染(仪器：Lonza 4D-nucleofector)。如图4和5所示，将识别左右两端DNA序列的DdCBE各400ng及50ng含有编辑位点的T载体混合，之后使用SF-Cell Line 4D-nucleofector X-kit电转染HEK293FT细胞。对于有可用细胞系的动物，可直接采用上述相同方法，将识别左右两端DNA序列的DdCBE各400ng电转染细胞。
电转染完成后，将细胞接入12孔板中并培养24小时，接着使用含有2μg/mL的嘌呤霉素进行细胞筛选，培养48小时后将细胞消化离心，并收取细胞用于检测DNA突变效率。
收取的细胞样品DNA提取方式如下：采用30μL的QuickExtractTM DNA ExtractionSolution(Lucigen)重选细胞，之后65℃加热45min，接着涡旋离心并使用98℃加热2min。
采用2×Green Taq Mix(Vazyme)扩增T载体或线粒体DNA上含有编辑位点的目的片段，之后用于Sanger测序；或采用Phanta Super-Fidelity DNA polymerase(Vazyme)及高通量测序建库引物进行高通量测序分析编辑效率。高通量测序的编辑效果如图6所示。
(三)使用DdCBE构建线粒体DNA突变斑马鱼模型
根据体内编辑的Sanger测序及高通量测序结果，筛选编辑效率最高的G4247和G8892位点的DdCBE组合。将识别左右两侧DNA序列的DdCBE载体各10μg混合，之后使用Pme I(NEB)限制性内切酶使载体线性化。采用DNA Clean&ConcentratorTM-5试剂盒(ZymoResearch)回收DNA，之后按照说明书使用mMESSAGE mMACHINE T7 Ultra Kit(Life,AM1345)进行体外转录，转录的mRNA使用RNA Clean&ConcentratorTM-5(Zymo Research)进行回收，并分装冻于-80℃保存。
为了获得线粒体DNA突变的斑马鱼，在斑马鱼的1细胞期进行注射，RNA的注射浓度为100ng/μL。收取获得的F0代斑马鱼组织，提取DNA并采用(二)中所述方法进行Sanger测序及高通量测序，如图7和8所示结果，F0代斑马鱼编辑效果存在高低，G4247位点突变斑马鱼线粒体DNA上的编辑效率为6.36-23.48％，而G8892位点突变斑马鱼线粒体DNA上的编辑效率为5.78-88.32％。
(四)携带线粒体DNA突变的斑马鱼模拟人类疾病模型
首先选择具有较高编辑效率的G4247和G8892位点突变雌性斑马鱼与野生型雄性斑马鱼交配，获得F1代斑马鱼。如表2所示，可获得高于或低于F0代编辑效率的F1代斑马鱼。
表2：F1代斑马鱼编辑效率分析
为了验证携带线粒体突变的斑马鱼能否模拟人类疾病。选取编辑效率较高的G4247A的F1代斑马鱼进行表型分析，如图9-11的结果表明F1代斑马鱼运动机能受损，肌肉组织中线粒体脊结构被破坏。因此，采用基于高效组装TALE的线粒体DNA编辑系统编辑产生的线粒体DNA突变斑马鱼动物模型，可模拟人类线粒体DNA突变引起的线粒体疾病。
上述说明示出并描述了发明的实施例，总之，本发明提供了一种基于TALE组装的线粒体DNA编辑系统，包括一种快速组装TALE模块的方法和一种匹配于TALE组装的线粒体DNA编辑系统。实验证实，本发明的一种基于TALE组装的线粒体DNA编辑系统，使TALE模块的组装高效且价格低廉，操作简单且易于推广；同时，利用匹配与TALE模块高速组装方法的线粒体DNA编辑系统，能够成功实现线粒体DNA编辑。除斑马鱼外，本发明亦已成功用于构建小鼠、大鼠、猴等线粒体DNA突变动物模型，表明该方法具有很好的稳定性和可重复性。
(一)RVD文库氨基酸序列
1)AA1
PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD
2)AA2
QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
3)AA3
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
4)AA4
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV
5)AA5
AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA
6)AA6
IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI
7)AA7
ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
8)AA8
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
9)AA9
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
10)AA10
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS
11)AC1
PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA
12)AC2
QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
13)AC3
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
14)AC4
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV
15)AC5
AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA
16)AC6
IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI
17)AC7
ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
18)AC8
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
19)AC9
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
20)AC10
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS
21)AG1
PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE
22)AG2
QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
23)AG3
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
24)AG4
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV
25)AG5
AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA
26)AG6
IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI
27)AG7
ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
28)AG8
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
29)AG9
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
30)AG10
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
31)AT1
PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE
32)AT2
QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
33)AT3
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
34)AT4
VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV
35)AT5
AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA
36)AT6
IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI
37)AT7
ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
38)AT8
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
39)AT9
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
40)AT10
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
41)CA1
PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD
42)CA2
QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
43)CA3
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
44)CA4
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV
45)CA5
AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA
46)CA6
IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI
47)CA7
ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
48)CA8
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
49)CA9
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
50)CA10
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS
51)CC1
PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA
52)CC2
QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
53)CC3
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
54)CC4
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV
55)CC5
AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA
56)CC6
IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI
57)CC7
ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
58)CC8
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
59)CC9
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
60)CC10
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS
61)CG1
PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE
62)CG2
QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
63)CG3
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
64)CG4
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV
65)CG5
AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA
66)CG6
IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI
67)CG7
ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
68)CG8
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
69)CG9
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
70)CG10
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
71)CT1
PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE
72)CT2
QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
73)CT3
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
74)CT4
VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV
75)CT5
AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA
76)CT6
IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI
77)CT7
ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
78)CT8
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
79)CT9
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
80)CT10
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
81)GA1
PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD
82)GA2
QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
83)GA3
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
84)GA4
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV
85)GA5
AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA
86)GA6
IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI
87)GA7
ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
88)GA8
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
89)GA9
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
90)GA10
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS
91)GC1
PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA
92)GC2
QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
93)GC3
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
94)GC4
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV
95)GC5
AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA
96)GC6
IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI
97)GC7
ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
98)GC8
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
99)GC9
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
100)GC10
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS
101)GG1
PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE
102)GG2
QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
103)GG3
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
104)GG4
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV
105)GG5
AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA
106)GG6
IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI
107)GG7
ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
108)GG8
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
109)GG9
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
110)GG10
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
111)GT1
PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE
112)GT2
QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
113)GT3
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
114)GT4
VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV
115)GT5
AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA
116)GT6
IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI
117)GT7
ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
118)GT8
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
119)GT9
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
120)GT10
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
121)TA1
PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD
122)TA2
QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
123)TA3
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV
124)TA4
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV
125)TA5
AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA
126)TA6
IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI
127)TA7
ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
128)TA8
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
129)TA9
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
130)TA10
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS
131)TC1
PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA
132)TC2
QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
133)TC3
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV
134)TC4
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV
135)TC5
AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA
136)TC6
IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI
137)TC7
ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
138)TC8
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
139)TC9
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
140)TC10
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS
141)TG1
PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE
142)TG2
QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
143)TG3
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV
144)TG4
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV
145)TG5
AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA
146)TG6
IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI
147)TG7
ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
148)TG8
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
149)TG9
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
150)TG10
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
151)TT1
PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE
152)TT2
QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
153)TT3
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV
154)TT4
VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV
155)TT5
AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA
156)TT6
IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI
157)TT7
ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
158)TT8
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
159)TT9
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
160)TT10
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
161)pA7
ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
162)pA8
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
163)pA9
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA
164)pA10
SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS
165)pC7
ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
166)pC8
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
167)pC9
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA
168)pC10
SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS
169)pG7
ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
170)pG8
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
171)pG9
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
172)pG10
SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
173)pT7
ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
174)pT8
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
175)pT9
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA
176)pT10
SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS
177)hA8
SNIGGRPALESIVAQLSRPDPALAA
178)hA9
SNIGGRPALESIVAQLSRPDPALAA
179)hA10
SNIGGRPALESIVAQLSRPDPALAA
180)hA11
GLGQILAAGRRWRALLPSYLALIRRWP
181)hC8
SHDGGRPALESIVAQLSRPDPALAA
182)hC9
SHDGGRPALESIVAQLSRPDPALAA
183)hC10
SHDGGRPALESIVAQLSRPDPALAA
184)hC11
GLGHMTAAGRRWRALLPSYLALIRRWP
185)hG8
SNNGGRPALESIVAQLSRPDPALAA
186)hG9
SNNGGRPALESIVAQLSRPDPALAA
187)hG10
SNNGGRPALESIVAQLSRPDPALAA
188)hG11
GLGQTMAAGRRWRALLPSYLALIRRWP
189)hT8
SNGGGRPALESIVAQLSRPDPALAA
190)hT9
SNGGGRPALESIVAQLSRPDPALAA
191)hT10
SNGGGRPALESIVAQLSRPDPALAA
192)hT11
GLGQMGAAGRRWRALLPSYLALIRRWP
(二)RVD文库DNA序列
1)AA1
GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC
2)AA2
GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC
3)AA3
GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC
4)AA4
GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC
5)AA5
GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC
6)AA6
GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC
7)AA7
GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC
8)AA8
GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC
9)AA9
GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC
10)AA10
GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC
11)AC1
GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC
12)AC2
GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC
13)AC3
GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC
14)AC4
GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC
15)AC5
GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC
16)AC6
GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC
17)AC7
GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC
18)AC8
GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC
19)AC9
GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC
20)AC10
GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC
21)AG1
GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC
22)AG2
GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC
23)AG3
GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC
24)AG4
GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC
25)AG5
GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC
26)AG6
GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC
27)AG7
GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC
28)AG8
GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC
29)AG9
GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC
30)AG10
GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC
31)AT1
GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC
32)AT2
GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC
33)AT3
GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC
34)AT4
GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC
35)AT5
GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC
36)AT6
GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC
37)AT7
GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC
38)AT8
GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC
39)AT9
GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC
40)AT10
GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC
41)CA1
GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC
42)CA2
GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC
43)CA3
GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC
44)CA4
GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC
45)CA5
GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC
46)CA6
GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC
47)CA7
GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC
48)CA8
GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC
49)CA9
GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC
50)CA10
GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC
51)CC1
GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC
52)CC2
GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC
53)CC3
GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC
54)CC4
GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC
55)CC5
GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC
56)CC6
GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC
57)CC7
GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC
58)CC8
GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC
59)CC9
GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC
60)CC10
GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC
61)CG1
GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC
62)CG2
GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC
63)CG3
GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC
64)CG4
GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC
65)CG5
GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC
66)CG6
GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC
67)CG7
GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC
68)CG8
GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC
69)CG9
GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC
70)CG10
GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC
71)CT1
GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC
72)CT2
GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC
73)CT3
GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC
74)CT4
GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC
75)CT5
GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC
76)CT6
GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC
77)CT7
GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC
78)CT8
GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC
79)CT9
GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC
80)CT10
GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC
81)GA1
GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC
82)GA2
GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC
83)GA3
GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC
84)GA4
GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC
85)GA5
GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC
86)GA6
GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC
87)GA7
GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC
88)GA8
GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC
89)GA9
GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC
90)GA10
GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC
91)GC1
GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC
92)GC2
GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC
93)GC3
GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC
94)GC4
GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC
95)GC5
GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC
96)GC6
GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC
97)GC7
GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC
98)GC8
GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC
99)GC9
GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC
100)GC10
GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC
101)GG1
GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC
102)GG2
GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC
103)GG3
GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC
104)GG4
GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC
105)GG5
GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC
106)GG6
GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC
107)GG7
GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC
108)GG8
GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC
109)GG9
GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC
110)GG10
GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC
111)GT1
GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC
112)GT2
GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC
113)GT3
GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC
114)GT4
GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC
115)GT5
GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC
116)GT6
GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC
117)GT7
GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC
118)GT8
GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC
119)GT9
GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC
120)GT10
GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC
121)TA1
GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC
122)TA2
GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC
123)TA3
GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC
124)TA4
GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC
125)TA5
GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC
126)TA6
GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC
127)TA7
GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC
128)TA8
GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC
129)TA9
GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC
130)TA10
GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC
131)TC1
GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC
132)TC2
GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC
133)TC3
GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC
134)TC4
GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC
135)TC5
GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC
136)TC6
GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC
137)TC7
GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC
138)TC8
GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC
139)TC9
GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC
140)TC10
GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC
141)TG1
GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC
142)TG2
GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC
143)TG3
GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC
144)TG4
GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC
145)TG5
GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC
146)TG6
GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC
147)TG7
GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC
148)TG8
GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC
149)TG9
GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC
150)TG10
GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC
151)TT1
GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC
152)TT2
GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC
153)TT3
GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC
154)TT4
GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC
155)TT5
GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC
156)TT6
GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC
157)TT7
GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC
158)TT8
GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC
159)TT9
GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC
160)TT10
GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC
161)pA7
GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC
162)pA8
GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC
163)pA9
GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC
164)pA10
GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC
165)pC7
GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC
166)pC8
GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC
167)pC9
GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC
168)pC10
GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC
169)pG7
GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC
170)pG8
GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC
171)pG9
GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC
172)pG10
GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC
173)pT7
GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC
174)pT8
GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC
175)pT9
GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC
176)pT10
GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC
177)hA8
GGTCTCGaagtaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
178)hA9
GGTCTCGttccaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
179)hA10
GGTCTCGctctaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
180)hA11
GGTCTCGgtcaaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
181)hC8
GGTCTCGaagtcatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
182)hC9
GGTCTCGttcccatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
183)hC10
GGTCTCGctctcatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
184)hC11
GGTCTCGgtcacatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
185)hG8
GGTCTCGaagtaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
186)hG9
GGTCTCGttccaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
187)hG10
GGTCTCGctctaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
188)hG11
GGTCTCGgtcaaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
189)hT8
GGTCTCGaagtaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
190)hT9
GGTCTCGttccaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
191)hT10
GGTCTCGctctaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
192)hT11
GGTCTCGgtcaaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC
(三)定位骨架DNA序列
1)MTS-G1333N
atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
2)MTS-G1333C
atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggagcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
3)MTS-G1397N
atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggcccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggatctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
4）MTS-1397C
atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccgcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
5）NLS-G1333N
ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
6）NLS-G1333C
ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggagcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
7）NLS-G1397N
ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggcccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggatctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
8）NLS-1397C
ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccgcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg
（四）PCR扩增引物
1）上游引物
tgaccgcagtggaggcagtg
2）下游引物
Ttcactgcatccagcgcagg
序列表
<110> 南京医科大学
<120> 一种基于TALE组装的线粒体DNA编辑系统
<160> 394
<170> SIPOSequenceListing 1.0
<210> 1
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 1
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Asp
65 70
<210> 2
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 2
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Asp Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Asp Gln Val
65 70
<210> 3
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 3
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val
65
<210> 4
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 4
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val Val
65
<210> 5
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 5
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Asp Gln Val Val Ala
65
<210> 6
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 6
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
50 55 60
Gln Val Val Ala Ile
65
<210> 7
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 7
Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 8
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 8
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 9
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 9
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 10
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 10
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 11
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 11
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Ala
65 70
<210> 12
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 12
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Asp Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Ala Gln Val
65 70
<210> 13
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 13
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val
65
<210> 14
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 14
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val Val
65
<210> 15
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 15
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
20 25 30
Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Ala Gln Val Val Ala
65
<210> 16
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 16
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
20 25 30
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
50 55 60
Gln Val Val Ala Ile
65
<210> 17
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 17
Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val
20 25 30
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 18
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 18
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 19
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 19
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 20
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 20
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 21
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 21
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 22
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 22
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Asp Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 23
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 23
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 24
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 24
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 25
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 25
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 26
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 26
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 27
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 27
Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 28
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 28
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 29
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 29
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 30
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 30
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 31
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 31
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 32
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 32
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Asp Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 33
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 33
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 34
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 34
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 35
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 35
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 36
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 36
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 37
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 37
Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 38
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 38
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 39
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 39
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 40
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 40
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 41
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 41
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Asp
65 70
<210> 42
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 42
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Ala Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Asp Gln Val
65 70
<210> 43
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 43
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val
65
<210> 44
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 44
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val Val
65
<210> 45
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 45
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Asp Gln Val Val Ala
65
<210> 46
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 46
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
50 55 60
Gln Val Val Ala Ile
65
<210> 47
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 47
Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 48
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 48
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 49
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 49
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 50
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 50
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 51
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 51
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Ala
65 70
<210> 52
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 52
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Ala Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Ala Gln Val
65 70
<210> 53
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 53
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val
65
<210> 54
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 54
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val Val
65
<210> 55
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 55
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
20 25 30
Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Ala Gln Val Val Ala
65
<210> 56
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 56
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
20 25 30
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
50 55 60
Gln Val Val Ala Ile
65
<210> 57
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 57
Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val
20 25 30
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 58
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 58
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 59
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 59
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 60
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 60
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 61
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 61
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 62
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 62
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Ala Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 63
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 63
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 64
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 64
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 65
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 65
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 66
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 66
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 67
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 67
Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 68
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 68
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 69
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 69
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 70
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 70
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 71
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 71
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 72
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 72
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Ala Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 73
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 73
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 74
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 74
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 75
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 75
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 76
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 76
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 77
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 77
Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 78
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 78
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 79
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 79
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 80
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 80
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 81
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 81
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Asp
65 70
<210> 82
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 82
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Asp Gln Val
65 70
<210> 83
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 83
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val
65
<210> 84
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 84
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val Val
65
<210> 85
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 85
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Asp Gln Val Val Ala
65
<210> 86
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 86
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
50 55 60
Gln Val Val Ala Ile
65
<210> 87
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 87
Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 88
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 88
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 89
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 89
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 90
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 90
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 91
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 91
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Ala
65 70
<210> 92
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 92
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Ala Gln Val
65 70
<210> 93
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 93
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val
65
<210> 94
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 94
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val Val
65
<210> 95
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 95
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Ala Gln Val Val Ala
65
<210> 96
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 96
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
50 55 60
Gln Val Val Ala Ile
65
<210> 97
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 97
Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 98
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 98
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 99
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 99
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 100
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 100
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 101
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 101
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 102
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 102
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 103
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 103
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 104
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 104
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 105
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 105
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 106
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 106
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 107
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 107
Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 108
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 108
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 109
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 109
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 110
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 110
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 111
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 111
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 112
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 112
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 113
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 113
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 114
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 114
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 115
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 115
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 116
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 116
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 117
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 117
Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 118
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 118
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 119
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 119
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 120
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 120
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 121
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 121
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Asp
65 70
<210> 122
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 122
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Asp Gln Val
65 70
<210> 123
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 123
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val
65
<210> 124
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 124
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Asp Gln Val Val
65
<210> 125
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 125
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Asp Gln Val Val Ala
65
<210> 126
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 126
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp
50 55 60
Gln Val Val Ala Ile
65
<210> 127
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 127
Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 128
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 128
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 129
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 129
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 130
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 130
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 131
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 131
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Ala
65 70
<210> 132
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 132
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Ala Gln Val
65 70
<210> 133
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 133
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val
65
<210> 134
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 134
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Ala Gln Val Val
65
<210> 135
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 135
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Ala Gln Val Val Ala
65
<210> 136
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 136
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala
50 55 60
Gln Val Val Ala Ile
65
<210> 137
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 137
Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 138
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 138
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 139
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 139
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 140
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 140
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 141
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 141
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 142
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 142
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 143
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 143
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 144
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 144
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 145
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 145
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 146
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 146
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 147
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 147
Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 148
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 148
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 149
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 149
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 150
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 150
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 151
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 151
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
1 5 10 15
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
20 25 30
Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys
35 40 45
Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala
50 55 60
His Gly Leu Thr Pro Glu
65 70
<210> 152
<211> 70
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 152
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
1 5 10 15
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
20 25 30
Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala
35 40 45
Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly
50 55 60
Leu Thr Pro Glu Gln Val
65 70
<210> 153
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 153
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val
65
<210> 154
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 154
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
1 5 10 15
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
20 25 30
Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu
35 40 45
Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr
50 55 60
Pro Glu Gln Val Val
65
<210> 155
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 155
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
1 5 10 15
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
20 25 30
Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr
35 40 45
Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro
50 55 60
Glu Gln Val Val Ala
65
<210> 156
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 156
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
1 5 10 15
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
20 25 30
Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val
35 40 45
Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu
50 55 60
Gln Val Val Ala Ile
65
<210> 157
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 157
Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln
35 40 45
Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln
50 55 60
Val Val Ala Ile Ala
65
<210> 158
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 158
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 159
<211> 68
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 159
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala
65
<210> 160
<211> 69
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 160
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg
35 40 45
Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val
50 55 60
Val Ala Ile Ala Ser
65
<210> 161
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 161
Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val
20 25 30
Ala Ile Ala
35
<210> 162
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 162
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala
<210> 163
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 163
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala
<210> 164
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 164
Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala
20 25 30
Ile Ala Ser
35
<210> 165
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 165
Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val
20 25 30
Ala Ile Ala
35
<210> 166
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 166
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala
<210> 167
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 167
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala
<210> 168
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 168
Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala
20 25 30
Ile Ala Ser
35
<210> 169
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 169
Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala
35
<210> 170
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 170
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala
<210> 171
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 171
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala
<210> 172
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 172
Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser
35
<210> 173
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 173
Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu
1 5 10 15
Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val
20 25 30
Ala Ile Ala
35
<210> 174
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 174
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala
<210> 175
<211> 34
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 175
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala
<210> 176
<211> 35
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 176
Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu
1 5 10 15
Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala
20 25 30
Ile Ala Ser
35
<210> 177
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 177
Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 178
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 178
Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 179
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 179
Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 180
<211> 27
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 180
Gly Leu Gly Gln Ile Leu Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu
1 5 10 15
Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro
20 25
<210> 181
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 181
Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 182
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 182
Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 183
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 183
Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 184
<211> 27
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 184
Gly Leu Gly His Met Thr Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu
1 5 10 15
Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro
20 25
<210> 185
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 185
Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 186
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 186
Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 187
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 187
Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 188
<211> 27
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 188
Gly Leu Gly Gln Thr Met Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu
1 5 10 15
Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro
20 25
<210> 189
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 189
Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 190
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 190
Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 191
<211> 25
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 191
Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu
1 5 10 15
Ser Arg Pro Asp Pro Ala Leu Ala Ala
20 25
<210> 192
<211> 27
<212> PRT
<213> 人工序列(Artificial Sequence)
<400> 192
Gly Leu Gly Gln Met Gly Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu
1 5 10 15
Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro
20 25
<210> 193
<211> 1792
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 193
atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60
accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120
catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180
gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240
tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300
cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360
ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420
gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480
gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540
cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600
aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660
taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720
acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780
gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840
aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900
agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960
gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020
ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080
ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140
gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200
gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260
tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320
caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380
aaagggattg ggaggctccg gctcctacgc cctgggccca tatcagatct ctgccccaca 1440
gctgccagca tacaacggac agaccgtggg cacattctac tatgtgaatg acgccggcgg 1500
cctggagtct aaggtgttta gctccggcgg ctctggaggc agcaccaacc tgtctgacat 1560
catcgagaag gagacaggca agcagctggt catccaggag agcatcctga tgctgcccga 1620
agaagtcgaa gaagtgatcg gaaacaagcc tgagagcgat atcctggtcc ataccgccta 1680
cgacgagagt accgacgaaa atgtgatgct gctgacatcc gacgccccag agtataagcc 1740
ctgggctctg gtcatccagg attccaacgg agagaacaaa atcaaaatgc tg 1792
<210> 194
<211> 1942
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 194
atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60
accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120
catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180
gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240
tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300
cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360
ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420
gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480
gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540
cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600
aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660
taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720
acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780
gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840
aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900
agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960
gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020
ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080
ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140
gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200
gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260
tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320
caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380
aaagggattg ggaggctccc caacccccta ccctaactat gccaatgcag gacacgtgga 1440
gggacagagc gccctgttca tgcgggataa cggcatctcc gagggcctgg tgttccacaa 1500
caatcccgag ggcacctgcg gcttttgcgt gaacatgacc gagacactgc tgcccgagaa 1560
tgccaagatg acagtggtgc cacctgaggg agcaatccct gtgaagagag gcgccaccgg 1620
cgagacaaag gtgtttaccg gcaactctaa tagccctaag tccccaacaa agggcggctg 1680
ctctggaggc agcaccaacc tgtctgacat catcgagaag gagacaggca agcagctggt 1740
catccaggag agcatcctga tgctgcccga agaagtcgaa gaagtgatcg gaaacaagcc 1800
tgagagcgat atcctggtcc ataccgccta cgacgagagt accgacgaaa atgtgatgct 1860
gctgacatcc gacgccccag agtataagcc ctgggctctg gtcatccagg attccaacgg 1920
agagaacaaa atcaaaatgc tg 1942
<210> 195
<211> 1984
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 195
atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60
accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120
catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180
gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240
tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300
cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360
ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420
gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480
gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540
cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600
aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660
taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720
acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780
gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840
aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900
agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960
gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020
ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080
ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140
gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200
gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260
tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320
caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380
aaagggattg ggaggctccg gctcctacgc cctgggccca tatcagatct ctgccccaca 1440
gctgccagca tacaacggac agaccgtggg cacattctac tatgtgaatg acgccggcgg 1500
cctggagtct aaggtgttta gctccggcgg cccaaccccc taccctaact atgccaatgc 1560
aggacacgtg gagggacaga gcgccctgtt catgcgggat aacggcatct ccgagggcct 1620
ggtgttccac aacaatcccg agggcacctg cggcttttgc gtgaacatga ccgagacact 1680
gctgcccgag aatgccaaga tgacagtggt gccacctgag ggatctggag gcagcaccaa 1740
cctgtctgac atcatcgaga aggagacagg caagcagctg gtcatccagg agagcatcct 1800
gatgctgccc gaagaagtcg aagaagtgat cggaaacaag cctgagagcg atatcctggt 1860
ccataccgcc tacgacgaga gtaccgacga aaatgtgatg ctgctgacat ccgacgcccc 1920
agagtataag ccctgggctc tggtcatcca ggattccaac ggagagaaca aaatcaaaat 1980
gctg 1984
<210> 196
<211> 1750
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 196
atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60
accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120
catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180
gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240
tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300
cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360
ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420
gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480
gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540
cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600
aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660
taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720
acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780
gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840
aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900
agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960
gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020
ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080
ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140
gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200
gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260
tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320
caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380
aaagggattg ggaggctccg caatccctgt gaagagaggc gccaccggcg agacaaaggt 1440
gtttaccggc aactctaata gccctaagtc cccaacaaag ggcggctgct ctggaggcag 1500
caccaacctg tctgacatca tcgagaagga gacaggcaag cagctggtca tccaggagag 1560
catcctgatg ctgcccgaag aagtcgaaga agtgatcgga aacaagcctg agagcgatat 1620
cctggtccat accgcctacg acgagagtac cgacgaaaat gtgatgctgc tgacatccga 1680
cgccccagag tataagccct gggctctggt catccaggat tccaacggag agaacaaaat 1740
caaaatgctg 1750
<210> 197
<211> 1666
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 197
ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60
atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120
cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180
gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240
gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300
cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360
ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420
aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480
ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540
tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600
agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660
gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720
gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780
ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840
gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900
atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960
cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020
aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080
aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140
ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200
ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260
attgggaggc tccggctcct acgccctggg cccatatcag atctctgccc cacagctgcc 1320
agcatacaac ggacagaccg tgggcacatt ctactatgtg aatgacgccg gcggcctgga 1380
gtctaaggtg tttagctccg gcggctctgg aggcagcacc aacctgtctg acatcatcga 1440
gaaggagaca ggcaagcagc tggtcatcca ggagagcatc ctgatgctgc ccgaagaagt 1500
cgaagaagtg atcggaaaca agcctgagag cgatatcctg gtccataccg cctacgacga 1560
gagtaccgac gaaaatgtga tgctgctgac atccgacgcc ccagagtata agccctgggc 1620
tctggtcatc caggattcca acggagagaa caaaatcaaa atgctg 1666
<210> 198
<211> 1816
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 198
ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60
atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120
cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180
gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240
gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300
cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360
ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420
aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480
ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540
tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600
agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660
gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720
gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780
ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840
gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900
atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960
cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020
aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080
aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140
ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200
ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260
attgggaggc tccccaaccc cctaccctaa ctatgccaat gcaggacacg tggagggaca 1320
gagcgccctg ttcatgcggg ataacggcat ctccgagggc ctggtgttcc acaacaatcc 1380
cgagggcacc tgcggctttt gcgtgaacat gaccgagaca ctgctgcccg agaatgccaa 1440
gatgacagtg gtgccacctg agggagcaat ccctgtgaag agaggcgcca ccggcgagac 1500
aaaggtgttt accggcaact ctaatagccc taagtcccca acaaagggcg gctgctctgg 1560
aggcagcacc aacctgtctg acatcatcga gaaggagaca ggcaagcagc tggtcatcca 1620
ggagagcatc ctgatgctgc ccgaagaagt cgaagaagtg atcggaaaca agcctgagag 1680
cgatatcctg gtccataccg cctacgacga gagtaccgac gaaaatgtga tgctgctgac 1740
atccgacgcc ccagagtata agccctgggc tctggtcatc caggattcca acggagagaa 1800
caaaatcaaa atgctg 1816
<210> 199
<211> 1858
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 199
ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60
atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120
cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180
gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240
gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300
cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360
ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420
aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480
ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540
tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600
agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660
gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720
gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780
ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840
gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900
atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960
cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020
aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080
aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140
ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200
ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260
attgggaggc tccggctcct acgccctggg cccatatcag atctctgccc cacagctgcc 1320
agcatacaac ggacagaccg tgggcacatt ctactatgtg aatgacgccg gcggcctgga 1380
gtctaaggtg tttagctccg gcggcccaac cccctaccct aactatgcca atgcaggaca 1440
cgtggaggga cagagcgccc tgttcatgcg ggataacggc atctccgagg gcctggtgtt 1500
ccacaacaat cccgagggca cctgcggctt ttgcgtgaac atgaccgaga cactgctgcc 1560
cgagaatgcc aagatgacag tggtgccacc tgagggatct ggaggcagca ccaacctgtc 1620
tgacatcatc gagaaggaga caggcaagca gctggtcatc caggagagca tcctgatgct 1680
gcccgaagaa gtcgaagaag tgatcggaaa caagcctgag agcgatatcc tggtccatac 1740
cgcctacgac gagagtaccg acgaaaatgt gatgctgctg acatccgacg ccccagagta 1800
taagccctgg gctctggtca tccaggattc caacggagag aacaaaatca aaatgctg 1858
<210> 200
<211> 1624
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 200
ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60
atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120
cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180
gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240
gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300
cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360
ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420
aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480
ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540
tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600
agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660
gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720
gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780
ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840
gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900
atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960
cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020
aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080
aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140
ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200
ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260
attgggaggc tccgcaatcc ctgtgaagag aggcgccacc ggcgagacaa aggtgtttac 1320
cggcaactct aatagcccta agtccccaac aaagggcggc tgctctggag gcagcaccaa 1380
cctgtctgac atcatcgaga aggagacagg caagcagctg gtcatccagg agagcatcct 1440
gatgctgccc gaagaagtcg aagaagtgat cggaaacaag cctgagagcg atatcctggt 1500
ccataccgcc tacgacgaga gtaccgacga aaatgtgatg ctgctgacat ccgacgcccc 1560
agagtataag ccctgggctc tggtcatcca ggattccaac ggagagaaca aaatcaaaat 1620
gctg 1624
<210> 201
<211> 20
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 201
tgaccgcagt ggaggcagtg 20
<210> 202
<211> 20
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 202
ttcactgcat ccagcgcagg 20
<210> 203
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 203
ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60
ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120
cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180
ttctctgtca agcccacgga ctcaccccag atcagg 216
<210> 204
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 204
caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60
ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120
agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180
caagcccacg gactcacccc agatcaagtg gt 212
<210> 205
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 205
tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60
ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120
atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180
cccacggact caccccagat caagttgtag 210
<210> 206
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 206
gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60
ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaat 120
attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180
cacggactca ccccagatca agttgtagca a 211
<210> 207
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 207
gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60
gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaatatt 120
ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180
ggactcaccc cagatcaagt tgtagcgatt 210
<210> 208
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 208
gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60
tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaatattgg 120
tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180
actcacccca gatcaagttg tagcgatagc c 211
<210> 209
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 209
agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60
ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta atattggtgg 120
caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180
caccccagat caagttgtag cgattgcaag t 211
<210> 210
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 210
aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcttcc 208
<210> 211
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 211
ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcctct 208
<210> 212
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 212
ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcgtca 208
<210> 213
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 213
ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60
ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120
cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180
ttctctgtca agcccacgga ctaaccccag cgcagg 216
<210> 214
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 214
caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60
ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120
agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180
caagcccacg gactaacccc agcgcaagtg gt 212
<210> 215
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 215
tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60
ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagtc 120
atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180
cccacggact aaccccagcg caagttgtag 210
<210> 216
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 216
gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60
ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtcat 120
gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180
cacggactaa ccccagcgca agttgtagca a 211
<210> 217
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 217
gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60
gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtcatgac 120
ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180
ggactaaccc cagcgcaagt tgtagcgatt 210
<210> 218
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 218
gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60
tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtcatgacgg 120
tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180
actaacccca gcgcaagttg tagcgatagc c 211
<210> 219
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 219
agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60
ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagtc atgacggtgg 120
caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180
aaccccagcg caagttgtag cgattgcaag t 211
<210> 220
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 220
aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcttcc 208
<210> 221
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 221
ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcctct 208
<210> 222
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 222
ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcgtca 208
<210> 223
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 223
ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60
ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120
cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180
ttctctgtca agcccacggt ctgactccgg agcagg 216
<210> 224
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 224
caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60
ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120
agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180
caagcccacg gtctgactcc ggagcaagtg gt 212
<210> 225
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 225
tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60
ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120
acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180
cccacggtct gactccggag caagttgtag 210
<210> 226
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 226
gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60
ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaac 120
aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180
cacggtctga ctccggagca agttgtagca a 211
<210> 227
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 227
gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60
gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaacaat 120
ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180
ggtctgactc cggagcaagt tgtagcgatt 210
<210> 228
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 228
gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60
tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaacaatgg 120
tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180
tctgactccg gagcaagttg tagcgatagc c 211
<210> 229
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 229
agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60
ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta acaatggtgg 120
caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180
gactccggag caagttgtag cgattgcaag t 211
<210> 230
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 230
aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcttcc 208
<210> 231
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 231
ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcctct 208
<210> 232
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 232
ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcgtca 208
<210> 233
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 233
ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60
ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120
cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180
ttctctgtca agcccacggc ctgacgcccg agcagg 216
<210> 234
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 234
caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60
ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120
agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180
caagcccacg gcctgacgcc cgagcaagtg gt 212
<210> 235
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 235
tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60
ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120
atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180
cccacggcct gacgcccgag caagttgtag 210
<210> 236
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 236
gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60
ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaat 120
gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180
cacggcctga cgcccgagca agttgtagca a 211
<210> 237
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 237
gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60
gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaatggg 120
ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180
ggcctgacgc ccgagcaagt tgtagcgatt 210
<210> 238
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 238
gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60
tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaatggggg 120
tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180
cctgacgccc gagcaagttg tagcgatagc c 211
<210> 239
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 239
agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60
ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta atgggggtgg 120
caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180
gacgcccgag caagttgtag cgattgcaag t 211
<210> 240
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 240
aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcttcc 208
<210> 241
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 241
ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcctct 208
<210> 242
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 242
ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcgtca 208
<210> 243
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 243
ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60
tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120
cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180
ttctctgtca agcccacgga ctcaccccag atcagg 216
<210> 244
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 244
caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60
cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120
agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180
caagcccacg gactcacccc agatcaagtg gt 212
<210> 245
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 245
tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60
taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120
atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180
cccacggact caccccagat caagttgtag 210
<210> 246
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 246
gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60
ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaat 120
attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180
cacggactca ccccagatca agttgtagca a 211
<210> 247
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 247
gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60
gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaatatt 120
ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180
ggactcaccc cagatcaagt tgtagcgatt 210
<210> 248
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 248
gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60
tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaatattgg 120
tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180
actcacccca gatcaagttg tagcgatagc c 211
<210> 249
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 249
agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60
ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta atattggtgg 120
caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180
caccccagat caagttgtag cgattgcaag t 211
<210> 250
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 250
aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcttcc 208
<210> 251
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 251
ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcctct 208
<210> 252
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 252
ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcgtca 208
<210> 253
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 253
ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60
tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120
cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180
ttctctgtca agcccacgga ctaaccccag cgcagg 216
<210> 254
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 254
caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60
cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120
agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180
caagcccacg gactaacccc agcgcaagtg gt 212
<210> 255
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 255
tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60
taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagtc 120
atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180
cccacggact aaccccagcg caagttgtag 210
<210> 256
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 256
gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60
ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtcat 120
gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180
cacggactaa ccccagcgca agttgtagca a 211
<210> 257
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 257
gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60
gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtcatgac 120
ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180
ggactaaccc cagcgcaagt tgtagcgatt 210
<210> 258
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 258
gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60
tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtcatgacgg 120
tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180
actaacccca gcgcaagttg tagcgatagc c 211
<210> 259
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 259
agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60
ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagtc atgacggtgg 120
caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180
aaccccagcg caagttgtag cgattgcaag t 211
<210> 260
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 260
aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcttcc 208
<210> 261
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 261
ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcctct 208
<210> 262
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 262
ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcgtca 208
<210> 263
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 263
ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60
tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120
cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180
ttctctgtca agcccacggt ctgactccgg agcagg 216
<210> 264
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 264
caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60
cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120
agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180
caagcccacg gtctgactcc ggagcaagtg gt 212
<210> 265
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 265
tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60
taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120
acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180
cccacggtct gactccggag caagttgtag 210
<210> 266
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 266
gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60
ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaac 120
aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180
cacggtctga ctccggagca agttgtagca a 211
<210> 267
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 267
gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60
gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaacaat 120
ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180
ggtctgactc cggagcaagt tgtagcgatt 210
<210> 268
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 268
gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60
tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaacaatgg 120
tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180
tctgactccg gagcaagttg tagcgatagc c 211
<210> 269
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 269
agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60
ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta acaatggtgg 120
caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180
gactccggag caagttgtag cgattgcaag t 211
<210> 270
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 270
aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcttcc 208
<210> 271
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 271
ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcctct 208
<210> 272
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 272
ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcgtca 208
<210> 273
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 273
ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60
tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120
cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180
ttctctgtca agcccacggc ctgacgcccg agcagg 216
<210> 274
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 274
caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60
cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120
agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180
caagcccacg gcctgacgcc cgagcaagtg gt 212
<210> 275
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 275
tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60
taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120
atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180
cccacggcct gacgcccgag caagttgtag 210
<210> 276
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 276
gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60
ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaat 120
gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180
cacggcctga cgcccgagca agttgtagca a 211
<210> 277
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 277
gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60
gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaatggg 120
ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180
ggcctgacgc ccgagcaagt tgtagcgatt 210
<210> 278
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 278
gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60
tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaatggggg 120
tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180
cctgacgccc gagcaagttg tagcgatagc c 211
<210> 279
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 279
agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60
ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta atgggggtgg 120
caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180
gacgcccgag caagttgtag cgattgcaag t 211
<210> 280
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 280
aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcttcc 208
<210> 281
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 281
ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcctct 208
<210> 282
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 282
ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcgtca 208
<210> 283
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 283
ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60
tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120
cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180
ttctctgtca agcccacgga ctcaccccag atcagg 216
<210> 284
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 284
caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60
ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120
agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180
caagcccacg gactcacccc agatcaagtg gt 212
<210> 285
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 285
tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60
tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120
atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180
cccacggact caccccagat caagttgtag 210
<210> 286
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 286
gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60
ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaat 120
attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180
cacggactca ccccagatca agttgtagca a 211
<210> 287
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 287
gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60
gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaatatt 120
ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180
ggactcaccc cagatcaagt tgtagcgatt 210
<210> 288
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 288
gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60
tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaatattgg 120
tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180
actcacccca gatcaagttg tagcgatagc c 211
<210> 289
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 289
agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60
ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta atattggtgg 120
caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180
caccccagat caagttgtag cgattgcaag t 211
<210> 290
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 290
aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcttcc 208
<210> 291
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 291
ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcctct 208
<210> 292
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 292
ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcgtca 208
<210> 293
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 293
ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60
tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120
cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180
ttctctgtca agcccacgga ctaaccccag cgcagg 216
<210> 294
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 294
caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60
ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120
agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180
caagcccacg gactaacccc agcgcaagtg gt 212
<210> 295
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 295
tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60
tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagtc 120
atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180
cccacggact aaccccagcg caagttgtag 210
<210> 296
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 296
gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60
ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtcat 120
gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180
cacggactaa ccccagcgca agttgtagca a 211
<210> 297
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 297
gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60
gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtcatgac 120
ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180
ggactaaccc cagcgcaagt tgtagcgatt 210
<210> 298
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 298
gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60
tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtcatgacgg 120
tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180
actaacccca gcgcaagttg tagcgatagc c 211
<210> 299
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 299
agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60
ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagtc atgacggtgg 120
caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180
aaccccagcg caagttgtag cgattgcaag t 211
<210> 300
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 300
aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcttcc 208
<210> 301
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 301
ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcctct 208
<210> 302
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 302
ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcgtca 208
<210> 303
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 303
ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60
tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120
cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180
ttctctgtca agcccacggt ctgactccgg agcagg 216
<210> 304
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 304
caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60
ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120
agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180
caagcccacg gtctgactcc ggagcaagtg gt 212
<210> 305
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 305
tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60
tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120
acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180
cccacggtct gactccggag caagttgtag 210
<210> 306
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 306
gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60
ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaac 120
aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180
cacggtctga ctccggagca agttgtagca a 211
<210> 307
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 307
gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60
gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaacaat 120
ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180
ggtctgactc cggagcaagt tgtagcgatt 210
<210> 308
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 308
gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60
tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaacaatgg 120
tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180
tctgactccg gagcaagttg tagcgatagc c 211
<210> 309
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 309
agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60
ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta acaatggtgg 120
caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180
gactccggag caagttgtag cgattgcaag t 211
<210> 310
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 310
aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcttcc 208
<210> 311
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 311
ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcctct 208
<210> 312
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 312
ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcgtca 208
<210> 313
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 313
ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60
tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120
cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180
ttctctgtca agcccacggc ctgacgcccg agcagg 216
<210> 314
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 314
caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60
ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120
agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180
caagcccacg gcctgacgcc cgagcaagtg gt 212
<210> 315
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 315
tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60
tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120
atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180
cccacggcct gacgcccgag caagttgtag 210
<210> 316
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 316
gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60
ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaat 120
gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180
cacggcctga cgcccgagca agttgtagca a 211
<210> 317
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 317
gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60
gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaatggg 120
ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180
ggcctgacgc ccgagcaagt tgtagcgatt 210
<210> 318
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 318
gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60
tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaatggggg 120
tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180
cctgacgccc gagcaagttg tagcgatagc c 211
<210> 319
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 319
agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60
ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta atgggggtgg 120
caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180
gacgcccgag caagttgtag cgattgcaag t 211
<210> 320
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 320
aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcttcc 208
<210> 321
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 321
ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcctct 208
<210> 322
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 322
ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcgtca 208
<210> 323
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 323
ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60
ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120
cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180
ttctctgtca agcccacgga ctcaccccag atcagg 216
<210> 324
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 324
caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60
cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120
agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180
caagcccacg gactcacccc agatcaagtg gt 212
<210> 325
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 325
tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60
taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120
atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180
cccacggact caccccagat caagttgtag 210
<210> 326
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 326
gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60
ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaat 120
attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180
cacggactca ccccagatca agttgtagca a 211
<210> 327
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 327
gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60
gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaatatt 120
ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180
ggactcaccc cagatcaagt tgtagcgatt 210
<210> 328
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 328
gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60
tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaatattgg 120
tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180
actcacccca gatcaagttg tagcgatagc c 211
<210> 329
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 329
agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60
ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta atattggtgg 120
caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180
caccccagat caagttgtag cgattgcaag t 211
<210> 330
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 330
aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcttcc 208
<210> 331
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 331
ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcctct 208
<210> 332
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 332
ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120
acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180
cccagatcaa gttgtagcga ttgcgtca 208
<210> 333
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 333
ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60
ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120
cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180
ttctctgtca agcccacgga ctaaccccag cgcagg 216
<210> 334
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 334
caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60
cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120
agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180
caagcccacg gactaacccc agcgcaagtg gt 212
<210> 335
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 335
tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60
taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagtc 120
atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180
cccacggact aaccccagcg caagttgtag 210
<210> 336
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 336
gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60
ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtcat 120
gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180
cacggactaa ccccagcgca agttgtagca a 211
<210> 337
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 337
gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60
gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtcatgac 120
ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180
ggactaaccc cagcgcaagt tgtagcgatt 210
<210> 338
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 338
gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60
tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtcatgacgg 120
tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180
actaacccca gcgcaagttg tagcgatagc c 211
<210> 339
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 339
agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60
ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagtc atgacggtgg 120
caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180
aaccccagcg caagttgtag cgattgcaag t 211
<210> 340
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 340
aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcttcc 208
<210> 341
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 341
ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcctct 208
<210> 342
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 342
ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120
acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180
cccagcgcaa gttgtagcga ttgcgtca 208
<210> 343
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 343
ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60
ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120
cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180
ttctctgtca agcccacggt ctgactccgg agcagg 216
<210> 344
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 344
caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60
cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120
agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180
caagcccacg gtctgactcc ggagcaagtg gt 212
<210> 345
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 345
tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60
taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120
acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180
cccacggtct gactccggag caagttgtag 210
<210> 346
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 346
gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60
ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaac 120
aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180
cacggtctga ctccggagca agttgtagca a 211
<210> 347
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 347
gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60
gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaacaat 120
ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180
ggtctgactc cggagcaagt tgtagcgatt 210
<210> 348
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 348
gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60
tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaacaatgg 120
tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180
tctgactccg gagcaagttg tagcgatagc c 211
<210> 349
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 349
agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60
ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta acaatggtgg 120
caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180
gactccggag caagttgtag cgattgcaag t 211
<210> 350
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 350
aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcttcc 208
<210> 351
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 351
ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcctct 208
<210> 352
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 352
ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120
acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180
tccggagcaa gttgtagcga ttgcgtca 208
<210> 353
<211> 216
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 353
ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60
ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120
cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180
ttctctgtca agcccacggc ctgacgcccg agcagg 216
<210> 354
<211> 212
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 354
caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60
cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120
agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180
caagcccacg gcctgacgcc cgagcaagtg gt 212
<210> 355
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 355
tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60
taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120
atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180
cccacggcct gacgcccgag caagttgtag 210
<210> 356
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 356
gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60
ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaat 120
gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180
cacggcctga cgcccgagca agttgtagca a 211
<210> 357
<211> 210
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 357
gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60
gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaatggg 120
ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180
ggcctgacgc ccgagcaagt tgtagcgatt 210
<210> 358
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 358
gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60
tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaatggggg 120
tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180
cctgacgccc gagcaagttg tagcgatagc c 211
<210> 359
<211> 211
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 359
agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60
ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta atgggggtgg 120
caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180
gacgcccgag caagttgtag cgattgcaag t 211
<210> 360
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 360
aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcttcc 208
<210> 361
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 361
ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcctct 208
<210> 362
<211> 208
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 362
ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120
acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180
gcccgagcaa gttgtagcga ttgcgtca 208
<210> 363
<211> 109
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 363
agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60
ctgtcaagcc cacggactca ccccagatca agttgtagcg attgcaagt 109
<210> 364
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 364
aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcttcc 106
<210> 365
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 365
ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcctct 106
<210> 366
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 366
ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60
tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcgtca 106
<210> 367
<211> 109
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 367
agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60
ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgcaagt 109
<210> 368
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 368
aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcttcc 106
<210> 369
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 369
ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcctct 106
<210> 370
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 370
ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60
tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcgtca 106
<210> 371
<211> 109
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 371
agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60
ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgcaagt 109
<210> 372
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 372
aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcttcc 106
<210> 373
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 373
ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcctct 106
<210> 374
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 374
ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60
tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcgtca 106
<210> 375
<211> 109
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 375
agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60
ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgcaagt 109
<210> 376
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 376
aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcttcc 106
<210> 377
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 377
ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcctct 106
<210> 378
<211> 106
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 378
ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60
tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcgtca 106
<210> 379
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 379
aagtaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 380
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 380
ttccaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 381
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 381
ctctaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 382
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 382
gtcaaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 383
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 383
aagtcatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 384
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 384
ttcccatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 385
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 385
ctctcatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 386
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 386
gtcacatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 387
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 387
aagtaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 388
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 388
ttccaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 389
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 389
ctctaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 390
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 390
gtcaaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 391
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 391
aagtaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 392
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 392
ttccaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 393
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 393
ctctaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
<210> 394
<211> 76
<212> DNA
<213> 人工序列(Artificial Sequence)
<400> 394
gtcaaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60
tccggcgttg gccgcg 76
Claims (9)
1.一种基于TALE组装的线粒体DNA编辑系统，其特征在于该编辑系统包括RVD文库、线粒体定位骨架载体、细胞核定位骨架载体，RVD文库包含至少192个RVD模块，包括：160个双RVD模块、16个单RVD模块及16个半RVD模块。
2.根据权利要求1所述的线粒体DNA编辑系统，其特征在于：双RVD模块识别2个连续DNA碱基，从位置1到10，共有10个位置顺序，每个位置上有16种组合，因此共有160个双RVD模块；单RVD模块识别1个DNA碱基，从位置7-10，共有4个位置顺序，每个位置上有4种可能，因此共有16个单RVD模块；半RVD模块识别1个DNA碱基，位置为8-11，共有4个位置顺序，每个位置上有4种可能，因此共有16个半RVD模块。
3.根据权利要求2所述的线粒体DNA编辑系统，其特征在于：RVD文库中不同位置的双、单和半RVD载体序列，其在Bsa I限制性内切酶切割后产生具有位置特异性的粘性末端序列，可使RVD序列按位置顺序自动排列组装，可以组装识别14-21个碱基TALE。
4.根据权利要求3所述的线粒体DNA编辑系统，其特征在于：160个双RVD的氨基酸序列如Seq ID NO：1-160所示；16个单RVD的氨基酸序列如Seq ID NO：161-176所示；16个半RVD的氨基酸序列如Seq ID NO：177-192所示；160个双RVD的核苷酸序列如Seq ID NO：203-362所示；16个单RVD的核苷酸序列如Seq ID NO：363-378所示；16个半RVD的核苷酸序列如SeqID NO：379-394所示。
5.根据权利要求1所述的线粒体DNA编辑系统，其特征在于，所述线粒体定位骨架载体的主要元件从5’端到3’端依次为线粒体定位信号(MTS)、ccdb毒素基因、half DddAtox、尿嘧啶糖基化酶抑制基因(UGI)、氨卞青霉素抗性元件；4个线粒体定位骨架载体其核苷酸序列如Seq ID NO：193-196所示。
6.根据权利要求1所述的线粒体DNA编辑系统，其特征在于，所述细胞核定位骨架的主要元件从5’端到3’端依次为细胞核定位信号(NLS)、ccdb毒素基因、half DddAtox、尿嘧啶糖基化酶抑制基因(UGI)、氨卞青霉素抗性元件；4个细胞核定位骨架其核苷酸序列如SeqID NO：197-200所示。
7.根据权利要求5和6所述的线粒体DNA编辑系统，其特征在于：4个线粒体定位骨架载体和4个细胞核定位骨架载体的毒素基因ccdb两侧含有两个Bsa I酶切位点，酶切后产生不同的粘性末端用于特异性连接1号位置的双RVD模块和8-11号位置的半RVD模块。
8.一种采用权利要求1所述基于TALE组装的线粒体DNA编辑系统的编辑方法，其特征在于，包括以下步骤：
步骤1、根据所要编辑位点的DNA序列，设计TALE序列，选择权利要求1所述的RVD模块与骨架载体，通过Golden Gate克隆法一步完成载体组装，形成胞嘧啶碱基编辑器(DdCBE)；组装完成的DdCBE载体经过转化DH5α感受态、单克隆PCR验证、Sanger测序等步骤后，可获得正确组装的DdCBE载体；
步骤2、将正确组装的MTS-DdCBE转染所要编辑物种的细胞，或NLS-DdCBE与含有编辑位点的T载体共同转染HEK293FT细胞，通过Sanger测序或高通量测序检测DdCBE编辑效率，筛选对线粒体DNA或T载体编辑效果最好的DdCBE组合；
步骤3、将编辑效果最好的DdCBE进行体外转录，注射1细胞期受精卵，然后将胚胎移植到受体动物输卵管，或通过体外发育获得F0代动物；通过Sanger测序及高通量测序检测F0代的编辑效率，筛选高编辑效率的F0代动物；
步骤4、将高编辑效率的雌性F0代动物与野生型雄性动物交配，获得的F1代动物通过Sanger测序及高通量测序检测编辑效率，高编辑效率的动物则存在模拟人类疾病的可能。
9.权利要求8所述的编辑方法在制备模拟人类疾病的线粒体DNA突变动物模型中的应用。
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