CN113390666A - Method for detecting performance index of chemical substance in cell - Google Patents
Method for detecting performance index of chemical substance in cell Download PDFInfo
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- CN113390666A CN113390666A CN202110682860.8A CN202110682860A CN113390666A CN 113390666 A CN113390666 A CN 113390666A CN 202110682860 A CN202110682860 A CN 202110682860A CN 113390666 A CN113390666 A CN 113390666A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
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- Chemical Kinetics & Catalysis (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
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Priority Applications (1)
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CN202110682860.8A CN113390666B (en) | 2021-06-17 | 2021-06-17 | Method for detecting performance index of chemical substance in cell |
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CN202110682860.8A CN113390666B (en) | 2021-06-17 | 2021-06-17 | Method for detecting performance index of chemical substance in cell |
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CN113390666A true CN113390666A (en) | 2021-09-14 |
CN113390666B CN113390666B (en) | 2023-01-24 |
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Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1571848A (en) * | 2001-09-05 | 2005-01-26 | 普赖德普罗特奥米克斯公司 | Proteins in type 2 diabetes |
US20060105322A1 (en) * | 2003-06-30 | 2006-05-18 | Ajinomoto Co., Inc. | Intracellular metabolic flux analysis method using substrate labeled with isotope |
CN101031793A (en) * | 2005-06-07 | 2007-09-05 | 松下电器产业株式会社 | Apparatus for measuring the electrical physiology of cells and a method for manufacturing the same |
CN101484806A (en) * | 2006-05-17 | 2009-07-15 | 协乐民公司 | Method for automated tissue analysis |
CN102911938A (en) * | 2012-08-03 | 2013-02-06 | 华侨大学 | siRNA (si Ribonucleic Acid) sequence for targeted restrain of POLD1 genetic expression |
CN105784991A (en) * | 2016-05-25 | 2016-07-20 | 南昌德漫多科技有限公司 | Device and method for repeated immunostaining of same tissue section |
CN105899953A (en) * | 2013-11-05 | 2016-08-24 | 新加坡科技研究局 | Bladder carcinoma biomarkers |
US9759709B1 (en) * | 2016-09-16 | 2017-09-12 | The Florida International University Board Of Trustees | Devices and methods to monitor HIV-infection in presence of substance of abuse and/or therapeutic agent |
CN110850094A (en) * | 2019-11-22 | 2020-02-28 | 西安交通大学 | Immunohistochemical double-label single-staining kit and use method and application thereof |
CN111317830A (en) * | 2019-12-24 | 2020-06-23 | 吉林大学 | Research method of pharmacological effect of mangiferin on diabetes of mice |
CN111575336A (en) * | 2020-05-14 | 2020-08-25 | 华东理工大学 | Method for acquiring metabolic flux of intracellular central carbon metabolic pathway under metabolic steady isotope unsteady state |
CN111721862A (en) * | 2020-06-12 | 2020-09-29 | 山西大学 | Method for identifying depression energy metabolism abnormal pathway based on stable isotope tracing metabonomics |
CN112462058A (en) * | 2020-11-20 | 2021-03-09 | 上海交通大学 | Circulating nerve cell detection kit and detection method |
-
2021
- 2021-06-17 CN CN202110682860.8A patent/CN113390666B/en active Active
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1571848A (en) * | 2001-09-05 | 2005-01-26 | 普赖德普罗特奥米克斯公司 | Proteins in type 2 diabetes |
US20060105322A1 (en) * | 2003-06-30 | 2006-05-18 | Ajinomoto Co., Inc. | Intracellular metabolic flux analysis method using substrate labeled with isotope |
CN101031793A (en) * | 2005-06-07 | 2007-09-05 | 松下电器产业株式会社 | Apparatus for measuring the electrical physiology of cells and a method for manufacturing the same |
CN101484806A (en) * | 2006-05-17 | 2009-07-15 | 协乐民公司 | Method for automated tissue analysis |
CN102911938A (en) * | 2012-08-03 | 2013-02-06 | 华侨大学 | siRNA (si Ribonucleic Acid) sequence for targeted restrain of POLD1 genetic expression |
CN105899953A (en) * | 2013-11-05 | 2016-08-24 | 新加坡科技研究局 | Bladder carcinoma biomarkers |
CN105784991A (en) * | 2016-05-25 | 2016-07-20 | 南昌德漫多科技有限公司 | Device and method for repeated immunostaining of same tissue section |
US9759709B1 (en) * | 2016-09-16 | 2017-09-12 | The Florida International University Board Of Trustees | Devices and methods to monitor HIV-infection in presence of substance of abuse and/or therapeutic agent |
CN110850094A (en) * | 2019-11-22 | 2020-02-28 | 西安交通大学 | Immunohistochemical double-label single-staining kit and use method and application thereof |
CN111317830A (en) * | 2019-12-24 | 2020-06-23 | 吉林大学 | Research method of pharmacological effect of mangiferin on diabetes of mice |
CN111575336A (en) * | 2020-05-14 | 2020-08-25 | 华东理工大学 | Method for acquiring metabolic flux of intracellular central carbon metabolic pathway under metabolic steady isotope unsteady state |
CN111721862A (en) * | 2020-06-12 | 2020-09-29 | 山西大学 | Method for identifying depression energy metabolism abnormal pathway based on stable isotope tracing metabonomics |
CN112462058A (en) * | 2020-11-20 | 2021-03-09 | 上海交通大学 | Circulating nerve cell detection kit and detection method |
Non-Patent Citations (2)
Title |
---|
刘池波等: "蛋白质组学技术在胃癌诊断中的应用及临床意义", 《中国热带医学》 * |
王宁: "适量UV照射对脑内谷氨酸合成新通路的影响", 《中国博士学位论文全文数据库 基础科学辑》 * |
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CN113390666B (en) | 2023-01-24 |
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