CN1133706A - Photothermal laser probe - Google Patents
Photothermal laser probe Download PDFInfo
- Publication number
- CN1133706A CN1133706A CN 96101822 CN96101822A CN1133706A CN 1133706 A CN1133706 A CN 1133706A CN 96101822 CN96101822 CN 96101822 CN 96101822 A CN96101822 A CN 96101822A CN 1133706 A CN1133706 A CN 1133706A
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- China
- Prior art keywords
- probe
- shell
- central canal
- handle
- laser probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
A therapeutic optical fibre probe has a transparent cylindrical shell with sealed front end and an opening end nested with cylindrical probe handle having a central tube, through which optical fibre and thermocouple wires pass, which are respectively arranged at inside of sealed front end and internal wall of shell. Water inlet and outet tubes are set up in central tube. The both ends of probe handle and central tube are sealed. It features the contact of probe with nidus for reducing reflection and increasing the efficiency of killing cancer cells and the use of thermocouple and cooling water for observing the temp variation of probe externally and double effects of using high temp and light energy to cure cancer.
Description
The present invention relates to a kind of optical fiber treatment probe.
Light power (PDT) therapy be develop rapidly the seventies control the cancer new technique, it is to use a kind of close tumorous photosensitizer-hematoporphyrin derivative (HPD) that has, utilize the irradiation of specific wavelength visible laser to contain the tumor by local of high concentration HPD, make it produce unit price attitude oxygen, thereby oxidation is killed cancerous cell and is destroyed the tumor by local blood vessel, reaches the purpose of controlling cancer.A large amount of practices show that light power is directly proportional with light dosage to the lethal effect of cancerous cell, and high temperature can quicken the lethal effect of PDT to cancerous cell.Because existing optical fiber treatment probe is made imperfection, optical fiber head cooperates not good with the human body corresponding organ, can not satisfy the needs of clinical treatment, often makes the light dosage deficiency that is subjected to according to district's focus, does not reach the purpose of thorough destruction focus.Though the short term effect that patient accepts after the PDT treatment is better, late result is not good.The optical fiber head that its main cause is to use is tiny, and the diffusion-type column optical fiber head that for example is used for esophagus can not contact with the esophageal wall focus, makes light produce reflection at esophageal mucosa membrane injury; Can not bear high-power visible laser again, influence the penetration depth of light.In addition, effective luminous component fragility of the optical fiber head that has the sixth of the twelve Earthly Branches, no shell holds, and makes optical fiber head easily be organized liquid and pollutes, and covers light source or produces fracture, influences Laser emission, causes the light skewness that is subjected to according to the district.Simultaneously,, in treatment, can not use high power laser owing to do not have cooling and temperature measuring equipment, can not be in the temperature variations of observation in vitro optical fiber head.Bring many inconvenience to clinical treatment.
Purpose of the present invention aims to provide a kind of can the raising and is subjected to shine the power density of distinguishing, and reaches the dual laser light of cancer effect of controlling of light power and high temperature according to probe.
The present invention has the shell of an employing light transmissive material, and shell is cylindrical, end sealing.The opening socket probe handle of shell, the probe handle is cylindric, and probe handle central axis is established central canal, and an end of optical fiber passes the sealed end inboard that central canal place shell.One end of thermocouple wire passes the inwall that central canal place shell.Also be provided with water inlet pipe and outlet pipe in the central canal, probe handle and central canal sealed at both ends makes probe handle inside be hollow-core construction, so that contain cooling water and fixedly central canal, optical fiber and thermocouple wire.
Shell can adopt the adhesive sealing with the junction of probe handle.The adhesive sealing also can be adopted in the two ends of probe handle and central canal, so that fixedly central canal, optical fiber, thermocouple wire, and inlet tube and outlet tube is fixed on the rear end of the handle of popping one's head in.
Optical fiber one end that is positioned at body seal end inboard preferably contacts with body seal end inwall.
Because the present invention adopts light transmissive material (for example quartz glass) to make the probing shell of all size, diffusion-type column optical fiber is established in inside, reasonable in design, can rationally select corresponding probe for use according to the narrow situation of focus clinically, probe is contacted with focus (for example esophageal wall focus), reduce the reflection of light at focal zone, therefore, improved the light dosage that is subjected to according to district's focus, promptly increased the light source power density that is subjected to according to district's focus, strengthened the killing-efficiency of light power cancerous cell.Secondly, owing to be equiped with thermocouple on probe top, can be in external direct observation probe temperature inside situation of change, at any time the temperature of may command probe, therefore, not only reach and utilize high-temperature and the dual purpose of controlling cancer of light power, and give the clinical science data that hyperthermia treatment of carcinoma is provided.Simultaneously, owing to be provided with chiller, so that cooling probe, thereby improve laser power, avoid popping one's head in superhigh temperature and damage normal structure and burn probe, it is safe in utilization, reliable.With the preliminary observation of curative effect of treatment esophageal carcinoma is example, and effective percentage can reach 91%, increases significantly than existing diffusion-type column optical fiber.
Fig. 1 is a structural representation of the present invention.
In Fig. 1, probing shell (1) adopting quartz glass is made, shell is cylindrical, top (11) is sealed to semicircle, the opening of shell (12) socket probe handle (2), the probe handle is cylindric, the junction of probe handle and shell adopts adhesive to be tightly connected, protrude in the outer part of shell aperture end (12) and be conical, probe handle central axis is established central canal (3), one end (41) of optical fiber (4) passes the inwall that central canal place shell top (11), one end (51) of thermocouple wire (5) passes the inwall that central canal (3) place shell, also be provided with water inlet pipe (6) and outlet pipe (7) in the central canal, the two ends of probe handle and the two ends of central canal can adopt adhesive to be tightly connected, so that make central canal optical fiber, thermocouple wire and water inlet pipe and water outlet pipe location.
One end (41) of optical fiber preferably contacts with the vertical inwall of shell, and an end (51) of thermocouple wire also contacts with the inwall of shell.Optical fiber is column optical fiber.The outfan of thermocouple wire is connected to thermometer.
Above-mentioned design is particularly suitable for as esophageal carcinoma treatment probe.
Claims (7)
1. photothermal laser probe is characterized in that
The shell that has a light transmissive material to make, shell is cylindrical, end sealing, the opening socket probe handle of shell, the probe handle is cylindric, establishes central canal in probe handle central axis;
One optical fiber is arranged, and an end of optical fiber passes the sealed end inboard that central canal place shell;
One thermocouple wire is arranged, and an end of thermocouple wire passes the inwall that central canal place shell;
Water inlet pipe and outlet pipe are arranged in the central canal, the sealed at both ends of handle and central canal of popping one's head in, probe handle inside is hollow-core construction.
2. photothermal laser probe as claimed in claim 1 is characterized in that the shell and the junction employing adhesive of probe handle are tightly connected, and the two ends of probe handle and central canal adopt adhesive to be tightly connected.
3. photothermal laser probe as claimed in claim 1 is characterized in that optical fiber one end that is positioned at body seal end inboard contacts with body seal end inwall.
4. photothermal laser probe as claimed in claim 1 is characterized in that shell adopting quartz glass material.
5. photothermal laser probe as claimed in claim 1, its characteristics are to place an end of the thermocouple wire of outer casing inner wall to contact with outer casing inner wall.
6. photothermal laser probe as claimed in claim 1 is characterized in that the apical end semicircular in shape of shell.
7. photothermal laser probe as claimed in claim 1 is characterized in that protruding in the outer part of shell aperture end and is conical.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96101822 CN1076192C (en) | 1996-01-16 | 1996-01-16 | Photothermal laser probe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96101822 CN1076192C (en) | 1996-01-16 | 1996-01-16 | Photothermal laser probe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1133706A true CN1133706A (en) | 1996-10-23 |
| CN1076192C CN1076192C (en) | 2001-12-19 |
Family
ID=5117283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96101822 Expired - Fee Related CN1076192C (en) | 1996-01-16 | 1996-01-16 | Photothermal laser probe |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1076192C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100420495C (en) * | 2000-10-31 | 2008-09-24 | 久保田茂弘 | Laser therapy method, highly laser beam-absorbing media to be used in the therapy and laser therapy apparatus with the use of the same |
-
1996
- 1996-01-16 CN CN 96101822 patent/CN1076192C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100420495C (en) * | 2000-10-31 | 2008-09-24 | 久保田茂弘 | Laser therapy method, highly laser beam-absorbing media to be used in the therapy and laser therapy apparatus with the use of the same |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1076192C (en) | 2001-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |