CN2559324Y - Solid tumor conical scattering laser therapeutical system - Google Patents

Solid tumor conical scattering laser therapeutical system Download PDF

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Publication number
CN2559324Y
CN2559324Y CN 02217726 CN02217726U CN2559324Y CN 2559324 Y CN2559324 Y CN 2559324Y CN 02217726 CN02217726 CN 02217726 CN 02217726 U CN02217726 U CN 02217726U CN 2559324 Y CN2559324 Y CN 2559324Y
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China
Prior art keywords
laser
tumor
tapered
therapy
head
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Expired - Fee Related
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CN 02217726
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Chinese (zh)
Inventor
洪德飞
童利民
彭淑牖
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Affiliated Sir Run Run Shaw Hospital of School of Medicine Zhejiang University
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Affiliated Sir Run Run Shaw Hospital of School of Medicine Zhejiang University
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Priority to CN 02217726 priority Critical patent/CN2559324Y/en
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Publication of CN2559324Y publication Critical patent/CN2559324Y/en
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Abstract

A physical tumor tapered dispersive laser therapy system, which mainly comprises a laser (1), a transmission fiber (2), a tapered dispersion laser therapy head (3) and a sleeve (4). Wherein, the laser therapy head (3) is a bare fiber core with a tapered and grinded surface. The utility model can effectively transform linear laser output by the fiber into upwards tapered laser, thus taking a shape of 'lamp shade' to radiate physical tumor tissues. In addition, it is unnecessary to pierce therapy head deep into the tumor. Tumor tissue intrusion can be reduced by radiating tumor edges. The utility model can not only enlarge thermal therapy scope and reduce radiation time but also avoid injuring blood vessels and other key structures out of the thermal therapy zone. With rational and novel structural design, the utility model is suitable for all shadow and deep physical tumor therapy.

Description

Entity tumor taper scattering laser therapy system
Technical field
This utility model belongs to medical apparatus and instruments, relates in particular to entity tumor taper scattering laser therapy system, is applicable to all shallow tables, deep entity tumor.As innocent and malignant tumours such as primary hepatocarcinoma, secondary liver cancer, pulmonary carcinoma, renal carcinoma, cancer of pancreas, uterus carcinoma, mastocarcinomas.
Background technology
Entity tumor is included in parenchymas such as China's hepatocarcinoma occurred frequently, pulmonary carcinoma, laryngeal carcinoma and clinical common gastrointestinal tract liver, lung transfer, is to cause main causes of death.Because the excision rate is quite low.As primary hepatocarcinoma, recurrent hepatocarcinoma, the excision rate of secondary liver cancer is lower than 25-30%.Bao Dao radio frequency (RFA), focus supersonic (HIFU), Nd:YAG local laser thermotherapy melted and reached excision entity tumor technology in recent years, had become the clinical focus of oncotherapy, abroad, the trend that replaces operation were arranged.Though these technology have obtained certain curative effect, because the expense costliness, curative effect is also unstable, is difficult to apply in China.Up to more than 1,300,000 yuan, the disposable electrode pin of each treatment is up to 1.5 ten thousand yuan as the radio frequency instrument and equipment, and (generally needing repeatedly treatment), each treatment needs more than 20,000 yuan, and dependence on import.Aspect clinical therapeutic efficacy, RFA thermal efficiency instability, treatment time is longer, and seance needed about half an hour.RFA is mainly used in diameter≤2cm, liver inner disease foci<4 hepatocarcinoma.The HIFU apparatus expensive, focus supersonic only equipment and instrument expense just up to more than 1,000 ten thousand yuan, temperature distributing disproportionation during thermotherapy, focal zone is too little, and treatment often need be carried out repeatedly, and ultrasonic incident passage has stopping of skeleton and gassiness tissue, there is certain blind area, the treatment degree of depth should be avoided skin burn greater than 2cm, and the HIFU treatment is used in the taboo of postcava cancer embolus.
The principle of Nd:YAG local laser heating ablation entity tumor: optical fiber treatment head implantation tumour center under B ultrasonic or CT guiding, laser irradiation then is converted into heat energy to luminous energy.Key problem in technology is that therapeutic domain is reached more than the treatment temperature, causes the tumor coagulation necrosis.Avoid local temperature too high again, make tissue vaporization and carbonization and influence laser, thereby influence the heat conduction, could effectively enlarge therapeutic domain and avoid damaging body the passing through of tumor tissues.Thermal therapy system mainly is made up of the first-class basic element of character of laser instrument, Transmission Fibers and laser therapy, and wherein laser and delivery are two important technology ginseng elements that influence systematic function and therapeutic effect.Business men provides finished product laser instrument and optical fiber, and the laser of exporting through optical fiber is the aggregation laser light distribution of linear type high-energy-density, can not be directly used in the heating ablation entity tumor.The treatment entity tumor must be converted into low-energy laser intensity and distribute this high-octane laser intensity by technical finesse.Have the bare fibre treatment head and the column type of at present external applied chemistry etch development are dispersed optical fiber treatment head.The former transmits heat and concentrates on the tip, easily causes the too high and carbonization of local temperature, further stops passing through of laser and affects the treatment.The latter uses suitable laser power and open-assembly time, disperse optical fiber and can evenly destroy bigger tumor and avoid carbonization, but the light intensity of laser is wayward, is not suitable for treating the entity tumor of the shallow table of internal organs.
Summary of the invention
The deficiency that this utility model exists at above-mentioned prior art, design a kind of entity tumor taper scattering laser therapy system, mainly form by laser instrument, Transmission Fibers and taper scattering laser treatment head, laser therapeutic head is exposed fibre core, its surperficial frosted is also tapered, the angle of taper is 10 °<α<90 °, laser therapeutic head is with sleeve pipe outward, use wavelength as the semiconductor laser of 810nm as output light source, Transmission Fibers and laser therapeutic head are for flexibly connecting, and laser therapeutic head is with sleeve pipe outward.
The entity tumor taper scattering laser therapy system of this utility model development is applicable to the treatment of all shallow tables, deep entity tumor, as innocent and malignant tumours such as primary hepatocarcinoma, secondary liver cancer, pulmonary carcinoma, renal carcinoma, cancer of pancreas, uterus carcinoma, mastocarcinomas.Have the following advantages: (1) light distribution is even, and form is easy to control, and different cone angles can obtain the light distribution of different spaces scope, thereby treats different transverse diameter size tumor; (2) scatter head effectively makes the linearity laser of optical fiber output be changed to most advanced and sophisticated up tapered, and like " lampshade " the same irradiation entity tumor tissue, during application, optical fiber head need not to thrust the tumor deep, only shines in the edge, can reduce the tumor tissues aggressive; (3) by a scattering optical fiber treatment scattering, make the disperse that is evenly distributed (low-power) of the high gathering light intensity of power, not only can enlarge the thermotherapy scope, shorten exposure time, also can avoid the damage of the important structure such as blood vessel outside the thermotherapy district.(4) scattering optical fiber treatment is simple for production, and economy is pollution-free; (5) laser fiber itself is sterilized, and can use repeatedly, and cheap (100 yuan/meter), value-for-money is beneficial to and promotes the use of; Cover overcoat when (6) laser therapeutic head of the present utility model uses not only can be avoided a directly contact tumor tissues of treatment head, and it is contaminated to prevent to pollute laser therapeutic head, thereby also can avoid and treat a tissue surface that head contacts and carbonization occurs and influence therapeutic effect.
Description of drawings
Fig. 1 is an entity tumor taper scattering laser therapy system structural representation.
Fig. 2 is taper scattering optical fiber treatment header structure sketch map.
Fig. 3 melts the hepatic tissue cross-sectional view for taper scattering laser optical fiber treatment feverish sensation in the head.
The specific embodiment
Embodiment 1: referring to Fig. 1, Fig. 2, entity tumor taper scattering laser therapy system is mainly by laser instrument (1), Transmission Fibers (2), taper scattering laser treatment head (3) and overcoat (4) are formed, it is that the semiconductor laser of 810nm is as output light source that laser instrument (1) is selected wavelength for use, laser therapeutic head (3) is exposed fibre core, its surperficial frosted is also tapered, the angle of taper is 10 °<α<90 °, the outer sleeve pipe (4) that is with of laser therapeutic head (3), prevent from directly to contact with organism, cause and organize carbonization and influence laser penetration power, light distribution by this taper scattering laser treatment head (3) output is even, be similar to a cone, Transmission Fibers (2) is to flexibly connect with laser therapeutic head (3), can change different laser therapeutic head (3) as required.
Embodiment 2: is length that one end of 10-15mm taper laser light scattering treatment head (3) is connected with laser instrument (2) output optical fibre, laser instrument (2) uses Britain to produce DioMED30 type GaAIAs semiconductor laser, wavelength 810nm, power 0.5-30w, volume 175mm * 390mm * 387mm, net weight 12kg.As laser power 6.0w, (Germany) recording the scatter head output is 2.1w for Huttinger, Umkirch with surveying the energy device.Directly contact with biological tissue for isolating optical fiber treatment head (3), on scattering optical fiber treatment head (3), load onto glass bushing (4).As tested biological tissue, when 16 hepatic tissues of 10 minutes healthy rabbits of thermocoagulation, record 96.39 ± 3.97 ℃ of fiber optic hub temperature, with the hepatic tissue of 16 healthy rabbits apart from 46.10 ± 4.58 ℃ of optical fiber 10mm hepatic tissue temperature.1 month thermocoagulation necrosis of liver tissue of postoperative transverse diameter 31.0mm, and necrotic area noresidue living tissue (referring to Fig. 3).Effect obviously is better than domestic and international Nd:YAG report Nd:YAG laser, 2-6W 15-40 action time minute, domesticated dog hepatic tissue coagulation necrosis diameter 15mm.
Does LASER HEAT melt entity tumor and melts healthy biological tissue what difference is arranged? according to biological tissue and laser interaction research, laser penetration rate as secondary liver cancer, hepatocellular carcinoma is stronger than normal liver tissue, and the laser of 670nmYAG is respectively 0.75mm, 0.97mm, 1.43mm, 2.78mm in the tissue penetration rate of normal hepatocytes, sclerosis liver, hepatocarcinoma, transfer hepatocarcinoma.The laser penetration rate is the important technology parameter that melts the entity tumor volume, and penetrance is strong more, and it is big more to melt diameter.Therefore, the effect of quasiconductor scattering laser thermocoagulation hepatocarcinoma may be better than hepatic tissue.When melting the entity tumor of more volume, can be according to the tumor major diameter, the treatment head of transposing respective length according to the tumor transverse diameter, can be used light splitting technology or the optical fiber more than 2 acts on simultaneously, the thermal field complementation.Use that this utility model technology is little to the body influence, complication is few, can carry out repeatedly, be applicable to that local thermotherapy melts entity tumors such as hepatocarcinoma, pulmonary carcinoma, finally reach the excision purpose.

Claims (5)

1. entity tumor taper scattering laser therapy system is made up of laser instrument 1, Transmission Fibers 2 and laser therapeutic head 3, it is characterized in that: laser therapeutic head 3 is exposed fibre core, and its surperficial frosted is also tapered.
2. entity tumor taper scattering laser therapy system according to claim 1 is characterized in that: the angle of taper is 10 °<α<90 °.
3. entity tumor taper scattering laser therapy system according to claim 1 is characterized in that: it is that the semiconductor laser of 810nm is as output laser that laser instrument 1 adopts wavelength.
4. entity tumor taper scattering laser therapy system according to claim 1 is characterized in that: Transmission Fibers 2 is flexible connection with laser therapeutic head 3.
5. entity tumor taper scattering laser therapy system according to claim 1 is characterized in that: the laser therapeutic head 3 outer sleeve pipes 4 that are with.
CN 02217726 2002-05-26 2002-05-26 Solid tumor conical scattering laser therapeutical system Expired - Fee Related CN2559324Y (en)

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CN 02217726 CN2559324Y (en) 2002-05-26 2002-05-26 Solid tumor conical scattering laser therapeutical system

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110051937A (en) * 2019-01-22 2019-07-26 吴威 A kind of optical fiber fat melting equipment
CN111557734A (en) * 2020-05-07 2020-08-21 徐州佳智信息科技有限公司 Laser ablation navigation system based on VR scene and method thereof
CN116755190A (en) * 2023-06-21 2023-09-15 青岛镭视光电科技有限公司 Side-transmitting optical fiber and laser medical device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110051937A (en) * 2019-01-22 2019-07-26 吴威 A kind of optical fiber fat melting equipment
CN111557734A (en) * 2020-05-07 2020-08-21 徐州佳智信息科技有限公司 Laser ablation navigation system based on VR scene and method thereof
CN116755190A (en) * 2023-06-21 2023-09-15 青岛镭视光电科技有限公司 Side-transmitting optical fiber and laser medical device
CN116755190B (en) * 2023-06-21 2024-04-19 青岛镭视光电科技有限公司 Side-transmitting optical fiber and laser medical device

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