CN113337387A

CN113337387A - Air filtering device and filtering method for adenine fermentation tank

Info

Publication number: CN113337387A
Application number: CN202110617706.2A
Authority: CN
Inventors: 笪猛雷; 李伯成; 李建兵
Original assignee: Ningxia Huaji Biological Co Ltd
Current assignee: Ningxia Huaji Biological Co Ltd
Priority date: 2021-06-03
Filing date: 2021-06-03
Publication date: 2021-09-03
Anticipated expiration: 2041-06-03
Also published as: CN113337387B

Abstract

The invention relates to the technical field of adenine fermentation, and discloses an adenine fermentation tank air filtering device and a filtering method, wherein the adenine fermentation tank air filtering device comprises an activated carbon filter, a sterilizing filter and a fermentation tank, and a sterilizing component is arranged at the pipeline connection position of the sterilizing filter and the fermentation tank; the sterilization assembly comprises an outer casing, and a first port and a second port of the outer casing are respectively connected with the air outlet end of the sterilization filter and the air inlet end of the fermentation tank; filterable clean air advances in the pipe gets into the fermentation cylinder by outlet duct and gas, when needs disinfect, only need to close gas and advance the pipe, and open steam shutoff valve, make steam advance intraductal steam by the four-way pipe get into in degerming filter and the active carbon filter, disinfect, whole process accessible control system automatic control, do not need the people to manually disinfect, time saving and labor saving, and simultaneously, the device need not dismantle the pipeline, just can let in steam sterilization, promote the device's sterilization efficiency greatly.

Description

Air filtering device and filtering method for adenine fermentation tank

Technical Field

The invention relates to the technical field of adenine fermentation, in particular to an air filtering device and a filtering method for an adenine fermentation tank.

Background

Adenine is used as a medical intermediate, is mainly used for participating in the synthesis of DNA and RNA, is used for treating leucopenia caused by radiotherapy, benzene poisoning, tumor resistance and the like, and is used for acute granulocytopenia, medicine and biochemical research.

At present, adenine is mainly produced by a fermentation method, and in the process of fermentation, a fermentation tank is required, and the fermentation tank main body is generally a main cylinder made of a stainless steel plate. The structure is strict and reasonable in design and processing. The steam sterilization resistant energy-saving device has the advantages of steam sterilization resistance, certain operation elasticity, minimized internal accessories, strong material and energy transfer performance, and certain adjustment to facilitate cleaning and reduce pollution, and is suitable for production of various products and energy consumption reduction.

Since the fermentation process needs to be performed under aseptic and pollution-free conditions, it is necessary to ensure that the fermentation tank is in a sealed state during the fermentation process. The fermentation of aerobic bacteria needs to continuously introduce a large amount of sterile air into the fermentation tank, so that the air introduction is needed to be added on the fermentation tank, air flow is undoubtedly formed in the processes of inputting and outputting, and the pipelines adopt the filtering technology in order to prevent the entry of the mixed bacteria

The existing air filtering device needs to be sterilized after being used for a certain time, the pipeline needs to be disassembled in the current sterilization operation, and the pipeline is connected into an independent steam pipeline, so that the operation is troublesome.

Disclosure of Invention

Technical problem to be solved

Aiming at the defects of the prior art, the invention provides an adenine fermentation tank air filtering device and a filtering method, which have the advantages of steam sterilization without dismounting a pipeline, automatic operation, time saving and labor saving, and the problem that the operation is troublesome because the pipeline needs to be dismounted and an independent steam pipeline is connected in the existing sterilization operation is solved.

(II) technical scheme

In order to achieve the purpose, the invention provides the following technical scheme: an adenine fermentation tank air filtering device comprises an active carbon filter, a sterilizing filter and a fermentation tank, wherein a sterilizing component is arranged at the pipeline connection position of the sterilizing filter and the fermentation tank;

the sterilization assembly comprises an outer casing, a first port and a second port of the outer casing are respectively connected with the air outlet end of the sterilization filter and the air inlet end of the fermentation tank, a four-way pipe is arranged inside the outer casing, a third port of the four-way pipe is provided with steam inlet pipes, the air inlet ends of the steam inlet pipes are provided with steam regulating valves, and one end of the four-way pipe is provided with a steam blocking valve.

Preferably, the inlet end of activated carbon filter is equipped with the intake pipe, the end of giving vent to anger of bacteria removing filter is equipped with the outlet duct, the inlet end of fermentation cylinder is equipped with gaseous admission pipe, activated carbon filter with bacteria removing filter passes through the pipeline intercommunication, the one end of outlet duct with the port one of four-way pipe is connected, the port two of four-way pipe with gaseous admission union coupling.

By adopting the scheme, the compressed gas enters the activated carbon filter and the sterilization filter through the gas inlet pipe to be filtered, the filtered compressed gas enters the four-way pipe through the gas outlet pipe, and finally the compressed gas enters the fermentation tank through the gas inlet pipe on the four-way pipe.

Preferably, the inside of active carbon filter is equipped with the active carbon filter core, the inside of degerming filter is equipped with degerming filter core.

Through adopting above-mentioned scheme, the active carbon filter core filters impurity, and the filtration grade is SH level, and the degerming filter core filters bacteriophage such as bacterium, and the filtration grade is SZ level.

Preferably, a butterfly valve is arranged at the gas inlet end of the gas inlet pipe.

By adopting the scheme, the butterfly valve controls the opening and closing state of the gas inlet pipe.

Preferably, the port four of four-way pipe is equipped with the dry and cold gas and advances the pipe, the dry and cold gas advances the inlet end of pipe and is equipped with dry and cold gas flow valve, the other end of four-way pipe is installed dry and cold gas shutoff valve.

Through adopting above-mentioned scheme, after steam sterilization accomplishes, the work of the gaseous shutoff valve of control dry and cold makes the gaseous shutoff valve of dry and cold control dry and cold advance the intercommunication of pipe, makes in dry and cold gas advances pipe and four-way pipe entering air outlet by dry and cold gas, makes in dry and cold gas gets into active carbon filter and bacteria filter by the outlet duct again, clears away the moisture of high fever fast, saves sterilization efficiency greatly, simultaneously, promotes compressed air's cleanliness factor.

Preferably, the steam plugging valve and the dry and cold gas plugging valve both comprise a motor, a lead screw, a sliding block and a plugging plate, the output shaft of the motor is fixedly connected with the lead screw, the outer side wall of the lead screw is in threaded connection with the sliding block, and the outer side wall of the sliding block is fixedly connected with the plugging plate.

By adopting the scheme, the motor controls the screw rod to work, so that the sliding block on the screw rod moves, and the plugging plate on the outer side of the sliding block plugs the joint of the steam inlet pipe or the dry and cold gas inlet pipe, thereby realizing the purpose of controlling the valve.

Preferably, the blocking plate is of a rubber plate-shaped structure, and sealing rings are arranged at the joints of the steam inlet pipe and the dry and cold gas inlet pipe and the four-way pipe.

By adopting the scheme, the sealing ring and the rubber plate-shaped structure have good sealing performance.

An adenine fermentation tank air filtration method comprises the following steps:

s1: when the fermentation tank works, the compressed gas passes through the activated carbon filter and the sterilization filter to filter impurities and bacteria, and the filtered compressed gas enters the fermentation tank through a pipeline;

s2: when sterilization is carried out, the steam inlet pipe is controlled to be communicated with the steam outlet pipe, so that steam enters the activated carbon filter and the sterilization filter from the steam outlet pipe for sterilization;

s3: after sterilization is finished, controlling the dry and cold gas inlet pipe to be communicated with the gas outlet pipe, and enabling the dry and cold gas to enter the activated carbon filter and the sterilization filter for condensation to finish moisture adsorption;

s4: after the dehumidification is finished, the air outlet pipe is controlled to be communicated with the air inlet pipe, and the ventilation operation is continued.

(III) advantageous effects

Compared with the prior art, the invention provides an adenine fermentation tank air filtering device and a filtering method, which have the following beneficial effects:

through setting up the sterilization subassembly, the sterilization subassembly is arranged in between bacteria removal filter and the fermentation cylinder, the outlet duct is connected respectively to the four-way pipe in the sterilization subassembly, gas advances pipe and steam and advances the pipe, when the device normally works, steam shutoff valve advances the pipe to steam and carries out the shutoff, make filterable clean air advance in the pipe gets into the fermentation cylinder by outlet duct and gas, when needs disinfect, only need close gas and advance the pipe, and open steam shutoff valve, make steam advance intraductal steam by the four-way pipe get into in bacteria removal filter and the active carbon filter, disinfect, whole process accessible control system automatic control, do not need the manual sterilization of people, time saving and labor saving, and simultaneously, the device need not dismantle the pipeline, just can let in steam sterilization, promote the device's sterilization efficiency greatly.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of the sterilization assembly of the present invention, wherein the gas outlet conduit is in communication with the gas inlet conduit;

FIG. 3 is a schematic view of the sterilization assembly of the present invention, wherein the steam inlet conduit is in communication with the steam outlet conduit;

FIG. 4 is a schematic view of the sterilization assembly of the present invention, wherein the dry and cold gas inlet tube is connected to the gas outlet tube.

In the figure: 10. an activated carbon filter; 11. an activated carbon filter element; 12. an air inlet pipe; 20. a sterilizing filter; 21. a sterilizing filter element; 22. an air outlet pipe; 30. a sterilization assembly; 31. an outer casing; 32. a four-way pipe; 33. a steam inlet pipe; 34. a steam regulating valve; 35. a steam block valve; 351. a motor; 352. a screw rod; 353. a slider; 354. a plugging plate; 36. dry and cold gas inlet pipe; 37. a dry cold gas flow valve; 38. a dry and cold gas block valve; 40. a fermentation tank; 41. a gas inlet pipe; 42. butterfly valves.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example one

An adenine fermentation tank air filtering device comprises an active carbon filter 10, a sterilizing filter 20 and a fermentation tank 40, wherein an active carbon filter element 11 is arranged inside the active carbon filter 10, a sterilizing filter element 21 is arranged inside the sterilizing filter 20, a sterilizing assembly 30 is arranged at the pipeline connection position of the sterilizing filter 20 and the fermentation tank 40, an air inlet pipe 12 is arranged at the air inlet end of the active carbon filter 10, an air outlet pipe 22 is arranged at the air outlet end of the sterilizing filter 20, an air inlet pipe 41 is arranged at the air inlet end of the fermentation tank 40, a butterfly valve 42 is arranged at the air inlet end of the air inlet pipe 41, the active carbon filter 10 is communicated with the sterilizing filter 20 through a pipeline, one end of the air outlet pipe 22 is connected with a first port of a four-way pipe 32, and a second port of the four-way pipe 32 is connected with the air inlet pipe 41;

the sterilization assembly 30 comprises an outer casing 31, a first port and a second port of the outer casing 31 are respectively connected with the air outlet end of the sterilization filter 20 and the air inlet end of the fermentation tank 40, a four-way pipe 32 is arranged inside the outer casing 31, a third port of the four-way pipe 32 is provided with a steam inlet pipe 33, the air inlet end of the steam inlet pipe 33 is provided with a steam regulating valve 34, and one end of the four-way pipe 32 is provided with a steam blocking valve 35.

Referring to fig. 1-3, when in use, compressed air enters the activated carbon filter 10 and the sterilization filter 20 through the air inlet pipe 12 for filtration, the filtered compressed air enters the four-way pipe 32 through the air outlet pipe 22, and finally the compressed air enters the fermentation tank 40 through the air inlet pipe 41 on the four-way pipe 32, when the device normally works, the steam blocking valve 35 blocks the steam inlet pipe 33, so that filtered clean air enters the fermentation tank 40 through the air outlet pipe 22 and the air inlet pipe 41, when sterilization is required, only the butterfly valve 42 on the air inlet pipe 41 needs to be closed, and the steam blocking valve 35 is opened, so that steam in the steam inlet pipe 33 enters the sterilization filter 20 and the activated carbon filter 10 through the four-way pipe 32, and sterilization operation is completed.

Example two

The port four of four-way pipe 32 is equipped with dry cold gas and advances pipe 36, the inlet end that dry cold gas advances pipe 36 is equipped with dry cold gas flow valve 37, dry cold gas shutoff valve 38 is installed to the other end of four-way pipe 32, steam shutoff valve 35 and dry cold gas shutoff valve 38 all include motor 351, lead screw 352, slider 353 and shutoff board 354, motor 351's output shaft fixedly connected with lead screw 352, the lateral wall threaded connection of lead screw 352 has slider 353, the lateral wall fixedly connected with shutoff board 354 of slider 353, shutoff board 354 is the rubber platelike structure, steam advances pipe 33 and dry cold gas and advances the junction of pipe 36 and four-way pipe 32 and is equipped with the sealing washer.

Referring to fig. 1-4, after steam sterilization is completed, the dry and cold gas blocking valve 38 is controlled to operate, so that the motor 351 controls the screw rod 352 to operate, the slider 353 on the screw rod 352 moves, the blocking plate 354 on the outer side of the slider 353 blocks the connection of the steam inlet pipe 33 or the dry and cold gas inlet pipe 36, and the purpose of controlling the valve is achieved, so that the dry and cold gas blocking valve 38 controls the communication of the dry and cold gas inlet pipe 36, dry and cold gas enters the air outlet pipe 22 from the dry and cold gas inlet pipe 36 and the four-way pipe 32, and dry and cold gas enters the activated carbon filter 10 and the sterilizing filter 20 from the air outlet pipe 22, high-temperature moisture is rapidly removed, sterilization efficiency is greatly saved, and the cleanliness of compressed air is improved.

In this embodiment, the dry and cold gas is nitrogen gas, and nitrogen gas is inert gas, can not react with other materials in the equipment, and dry and cold nitrogen gas meets damp and hot gas and can adsorb moisture fast, discharges via the pipeline at last.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. An adenine fermentation cylinder air filter equipment, includes activated carbon filter (10), degerming filter (20) and fermentation cylinder (40), its characterized in that: a sterilizing component (30) is arranged at the pipeline connection position of the sterilizing filter (20) and the fermentation tank (40);

the sterilization assembly (30) includes outer shell (31), the port one and the port two of outer shell (31) respectively with the end of giving vent to anger of sterilization filter (20) with the inlet end of fermentation cylinder (40) is connected, the inside of outer shell (31) is equipped with four-way pipe (32), the port three of four-way pipe (32) is equipped with steam and advances pipe (33), the inlet end that steam advances pipe (33) is equipped with steam control valve (34), steam shutoff valve (35) are installed to the one end of four-way pipe (32).

2. The adenine fermenter air filtering device of claim 1, wherein: the inlet end of activated carbon filter (10) is equipped with intake pipe (12), the end of giving vent to anger of bacteria removing filter (20) is equipped with outlet duct (22), the inlet end of fermentation cylinder (40) is equipped with gaseous admission pipe (41), activated carbon filter (10) with bacteria removing filter (20) pass through the pipeline intercommunication, the one end of outlet duct (22) with the port one of four-way pipe (32) is connected, the port two of four-way pipe (32) with gaseous admission pipe (41) is connected.

3. The adenine fermenter air filtering device of claim 1, wherein: the inside of active carbon filter (10) is equipped with active carbon filter core (11), the inside of degerming filter (20) is equipped with degerming filter core (21).

4. The adenine fermenter air filtering device of claim 2, wherein: the air inlet end of the air inlet pipe (41) is provided with a butterfly valve (42).

5. The adenine fermenter air filtering device of claim 1, wherein: the port of four-way pipe (32) is equipped with futilely cold gas and advances pipe (36), the inlet end that futilely cold gas advances pipe (36) is equipped with futilely cold gas flow valve (37), dry cold gas shutoff valve (38) are installed to the other end of four-way pipe (32).

6. The adenine fermenter air filtering device of claim 5, wherein: the steam blocking valve (35) and the dry and cold gas blocking valve (38) comprise a motor (351), a screw rod (352), a sliding block (353) and a blocking plate (354), an output shaft of the motor (351) is fixedly connected with the screw rod (352), the outer side wall of the screw rod (352) is in threaded connection with the sliding block (353), and the outer side wall of the sliding block (353) is fixedly connected with the blocking plate (354).

7. The adenine fermenter air filtering device of claim 6, wherein: the blocking plate (354) is of a rubber plate-shaped structure, and sealing rings are arranged at the joints of the steam inlet pipe (33) and the dry and cold gas inlet pipe (36) and the four-way pipe (32).

8. An adenine fermenter air filtering method as claimed in any one of claims 1 to 7, comprising the steps of:

s1: when the device works, the compressed gas passes through the activated carbon filter (10) and the sterilizing filter (20) to filter impurities and bacteria, and the filtered compressed gas enters the fermentation tank (40) through a pipeline;

s2: when sterilization is carried out, the steam inlet pipe (33) is controlled to be communicated with the air outlet pipe (22), so that steam enters the activated carbon filter (10) and the sterilizing filter (20) from the air outlet pipe (22) for sterilization;

s3: after sterilization is finished, the dry and cold gas inlet pipe (36) is controlled to be communicated with the gas outlet pipe (22), so that the dry and cold gas enters the activated carbon filter (10) and the sterilizing filter (20) to be condensed, and the adsorption of moisture is finished;

s4: after the dehumidification is finished, the air outlet pipe (22) is controlled to be communicated with the air inlet pipe (41), and the ventilation operation is continued.