CN113304239A - Preparation method of traditional Chinese medicine patch for arthralgia - Google Patents
Preparation method of traditional Chinese medicine patch for arthralgia Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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Abstract
The invention discloses a preparation method of a traditional Chinese medicine patch for arthralgia, which is prepared from raw phellodendron, bletilla striata, raw kusnezoff monkshood root, niuwen, nutgrass galingale rhizome, common burreed rhizome, ephedra herb, Chinese starjasmine stem, drynaria rhizome, ginger, mint, stramonium, rhubarb, giant knotweed rhizome, red paeony root, cassia twig, beewax and white spirit.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to a preparation method of a traditional Chinese medicine patch for arthralgia.
Background
Arthritis or arthropathy has a wide range of involvement, a plurality of varieties and different causes, and common clinical symptoms can show arthralgia. Arthritis caused by any reason can be generally cured or relieved if patients can seek medical advice in time and treat the arthritis according to symptoms. In the prior art, most of mild arthralgia are applied by using patches, but the patches in the prior art are mostly chemical agents, some of the patches have quick drug effect but large side effect and damage skin, and the traditional Chinese medicine patches have slow drug effect and cannot timely relieve pain, so that an improvement space exists.
Disclosure of Invention
The present invention aims at providing the preparation method of the traditional Chinese medicine patch for treating arthralgia in order to solve the problems.
The invention realizes the purpose through the following technical scheme:
the preparation method of the traditional Chinese medicine patch for arthralgia comprises the following steps:
s1: preparing cortex Phellodendri, rhizoma Bletillae, radix Aconiti Kusnezoffii, radix Aristolochiae, rhizoma Cyperi, rhizoma Sparganii, herba Ephedrae, caulis Trachelospermi, rhizoma Drynariae, rhizoma Zingiberis recens, herba Menthae, herba Daturae, radix et rhizoma Rhei, rhizoma Polygoni Cuspidati, radix Paeoniae Rubra, ramulus Cinnamomi, Cera flava and Chinese liquor;
s2: drying the raw phellodendron, bletilla striata, raw kusnezoff monkshood root, the cow-bezoar, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig weighed in the step S1, and then putting the dried raw phellodendron, the bletilla striata, the raw kusnezoff monkshood root, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig into a pulverizer to pulverize into powder for later use;
s3: adding the white spirit into the mixture obtained in the step S2, uniformly mixing, sealing and storing for 5-7 days;
s4: adding the substance stored in the step S3 into heated beeswax, mixing uniformly, cooling and shaping, and cutting into 10g blocks;
s5: the preparation of the Chinese medicinal patch for arthralgia was completed by wrapping 10g of each mixture of step S4 with a square patch having a side length of 10X 12 cm.
Preferably, the block mixture in step S4 has a side length of 6 × 8 cm and a thickness of 0.2-0.3 cm.
Preferably, the powder of step S2 is sieved through a 400 mesh sieve.
Further, the traditional Chinese medicine composition comprises, by weight, 4-8 parts of the raw phellodendron amurense, 3-5 parts of the bletilla striata, 4-6 parts of the raw kusnezoff monkshood root, 5-10 parts of the cow-bezoar, 2-5 parts of the rhizoma cyperi, 2-5 parts of the rhizoma sparganii, 3-6 parts of the ephedra herb, 1-4 parts of the Chinese starjasmine stem, 5-10 parts of the rhizoma drynariae, 2-5 parts of the ginger, 1-4 parts of the mint, 1-2 parts of the stramonium, 2-5 parts of the rhubarb, 4-8 parts of the polygonum cuspidatum, 4-8 parts of the red peony root, 1-3 parts of the cassia twig, 10-15 parts of the beeswax and 10-20 parts of the white spirit.
Preferably, the traditional Chinese medicine composition comprises, by weight, 5 parts of the raw phellodendron amurense, 4 parts of the bletilla striata, 5 parts of the raw kusnezoff monkshood root, 8 parts of the cow-bezoar, 3 parts of the rhizoma cyperi, 3 parts of the rhizoma sparganii, 4 parts of the ephedra herb, 2 parts of the Chinese starjasmine stem, 6 parts of the rhizoma drynariae, 4 parts of the ginger, 2 parts of the mint, 1 part of the stramonium, 4 parts of the rhubarb, 6 parts of the giant knotweed rhizome, 6 parts of the red peony root, 2 parts of the cassia twig, 12 parts of the beeswax and 15 parts of the white spirit.
The invention has the beneficial effects that:
the invention relates to a preparation method of a traditional Chinese medicine patch for arthralgia, which is characterized in that a pure traditional Chinese medicine preparation is adopted, the action is small, scientifically compatible medicinal ingredients are effectively separated out by utilizing white spirit, the medicinal ingredients are prepared into a paste by matching with beeswax, the medicine permeability is large, the medicine can quickly reach a focus, the pain can be timely relieved when the joint is painful, the effect of treating mild arthralgia can be achieved, and the preparation method has popularization and application values.
Detailed Description
The invention is further illustrated below:
the preparation method of the traditional Chinese medicine patch for arthralgia comprises the following steps:
s1: preparing cortex Phellodendri, rhizoma Bletillae, radix Aconiti Kusnezoffii, radix Aristolochiae, rhizoma Cyperi, rhizoma Sparganii, herba Ephedrae, caulis Trachelospermi, rhizoma Drynariae, rhizoma Zingiberis recens, herba Menthae, herba Daturae, radix et rhizoma Rhei, rhizoma Polygoni Cuspidati, radix Paeoniae Rubra, ramulus Cinnamomi, Cera flava and Chinese liquor;
s2: drying the raw phellodendron, bletilla striata, raw kusnezoff monkshood root, the cow-bezoar, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig weighed in the step S1, and then putting the dried raw phellodendron, the bletilla striata, the raw kusnezoff monkshood root, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig into a pulverizer to pulverize into powder for later use;
s3: adding the white spirit into the mixture obtained in the step S2, uniformly mixing, sealing and storing for 5-7 days;
s4: adding the substance stored in the step S3 into heated beeswax, mixing uniformly, cooling and shaping, and cutting into 10g blocks;
s5: the preparation of the Chinese medicinal patch for arthralgia was completed by wrapping 10g of each mixture of step S4 with a square patch having a side length of 10X 12 cm.
Preferably, the block mixture in step S4 has a side length of 6 × 8 cm and a thickness of 0.2-0.3 cm.
Preferably, the powder of step S2 is sieved through a 400 mesh sieve.
Further, the traditional Chinese medicine composition comprises, by weight, 4-8 parts of the raw phellodendron amurense, 3-5 parts of the bletilla striata, 4-6 parts of the raw kusnezoff monkshood root, 5-10 parts of the cow-bezoar, 2-5 parts of the rhizoma cyperi, 2-5 parts of the rhizoma sparganii, 3-6 parts of the ephedra herb, 1-4 parts of the Chinese starjasmine stem, 5-10 parts of the rhizoma drynariae, 2-5 parts of the ginger, 1-4 parts of the mint, 1-2 parts of the stramonium, 2-5 parts of the rhubarb, 4-8 parts of the polygonum cuspidatum, 4-8 parts of the red peony root, 1-3 parts of the cassia twig, 10-15 parts of the beeswax and 10-20 parts of the white spirit.
Preferably, the traditional Chinese medicine composition comprises, by weight, 5 parts of the raw phellodendron amurense, 4 parts of the bletilla striata, 5 parts of the raw kusnezoff monkshood root, 8 parts of the cow-bezoar, 3 parts of the rhizoma cyperi, 3 parts of the rhizoma sparganii, 4 parts of the ephedra herb, 2 parts of the Chinese starjasmine stem, 6 parts of the rhizoma drynariae, 4 parts of the ginger, 2 parts of the mint, 1 part of the stramonium, 4 parts of the rhubarb, 6 parts of the giant knotweed rhizome, 6 parts of the red peony root, 2 parts of the cassia twig, 12 parts of the beeswax and 15 parts of the white spirit.
Raw phellodendron bark: has bitter taste, cold nature, and effects of cooling and settling, purging pathogenic fire, removing toxic substance, eliminating dampness, and clearing away heat and toxic materials; can be used for treating dysentery, diabetes, diarrhea, jaundice, lymphadenectasis, hemorrhoid, hematochezia, nocturnal emission, leucorrhea with red and white discharge, conjunctival congestion, bone steaming fatigue, aphtha of the mouth and tongue, pyocutaneous disease, and tinea pedis.
Bletilla striata: astringe to stop bleeding, resolve swelling and promote granulation, and can be used for hemoptysis, hematemesis, traumatic hemorrhage, pyocutaneous disease, pyogenic infection, and chapped skin.
Raw kusnezoff monkshood root: pungent, bitter and hot; it is toxic. It enters heart, liver, kidney and spleen meridians. Dispel wind and dampness, warm meridians and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia, and pain due to anesthesia.
Cattle characters: can be used for treating amenorrhea due to blood stasis; postpartum lochiorrhea; dry blood tuberculosis; blood is stored in the lower abdomen; mass of the abdominal mass; traumatic injury and pain; abscess and swelling; obstruction of the throat and the like.
Rhizoma cyperi: to soothe the liver, relieve depression, regulate qi, relieve epigastric distention, regulate menstruation and alleviate pain. Can be used for treating stagnation of qi due to depression of the liver, distending pain in chest and hypochondrium, hernia pain, breast pain, stagnation of qi in spleen and stomach, abdominal distention, fullness and pain, menoxenia, amenorrhea, and dysmenorrhea.
Three-edge: break blood and move qi, resolve food stagnation and alleviate pain. Can be used for treating abdominal mass, dysmenorrhea, blood stasis, amenorrhea, thoracic obstruction, heart pain, and pain due to food stagnation.
Herba ephedrae: pungent, slightly bitter and warm. It enters lung and bladder meridians. Induce sweating and dispel cold, ventilate lung and relieve dyspnea, induce diuresis to alleviate edema.
Caulis trachelospermi: dredging collaterals, relieving pain, cooling blood, clearing heat, removing toxic substance, and relieving swelling, and can be used for treating rheumatalgia, soreness of waist and knees, spasm of muscles and tendons, sore throat, furuncle, toxic swelling, traumatic injury, and traumatic hemorrhage
Rhizoma drynariae: the rhizoma drynariae rhizome used as the medicine is rich in effective components such as flavone, alkaloid, phenols and the like, and has the effects of removing blood stasis, relieving pain, reuniting bones and tendons, treating toothache, low back pain, chronic diarrhea and the like.
Ginger: sweating to relieve exterior syndrome, warming middle energizer to arrest vomiting, warming lung to relieve cough, and relieving fish and crab toxicity. Can be used for treating wind-cold invading exterior, stomach cold emesis, spleen deficiency diarrhea, fish and crab poisoning, etc. Modern pharmacological research shows that ginger has the functions of resisting bacteria, resisting cancer, resisting oxidation, resisting senility, etc.
Mint: is a pungent and cool sweating and heat-clearing medicine, and is used for treating influenza, headache, conjunctival congestion, fever, sore throat, gum swelling and pain, and the like. It can be used for treating neuralgia, skin pruritus, erythra, eczema, etc.
Datura stramonium: datura flower can be used not only for anesthesia but also for treating diseases. Its leaves, flowers and seeds can be used as medicine, and its taste is pungent and warm, and has strong toxicity. The flower can remove wind-damp, stop asthma and relieve pain, can be used for treating infantile convulsion and cold asthma, and can be decocted to wash for treating wind-evil, obstinate arthralgia, cold dampness and beriberi. Petal is especially good in analgesic effect, and can be used for treating neuralgia. The leaves and seeds can be used for relieving cough and pain.
Rhubarb: the rhubarb has the effects of clearing heat and relaxing bowels, clearing heat and purging, detoxifying and stimulating the menstrual flow and removing blood stasis, can be used for treating constipation caused by heat evil and can also be used for treating constipation caused by yang deficiency, and the rhubarb can be used for treating diseases such as sore, carbuncle and pyogenic infections, gum swelling and pain, oral ulcer and the like due to the detoxification effect of the rhubarb. Because the rhubarb has good functions of promoting blood circulation by removing blood stasis and regulating menstruation, the rhubarb can be used for treating irregular menstruation, traumatic injury and other diseases caused by blood stasis, and can be used for clearing damp-heat, and also can be used for treating urinary infection, dysuria, jaundice and other diseases caused by damp-heat.
Giant knotweed rhizome: dispel wind and remove dampness, dissipate blood stasis and relieve pain, relieve cough and resolve phlegm. Can be used for treating arthralgia, jaundice due to damp-heat pathogen, amenorrhea, abdominal mass, scald due to hot water or fire, traumatic injury, carbuncle, swelling, sore, and cough with excessive phlegm.
Red peony root: clear heat and cool blood, dissipate blood stasis and alleviate pain. Can be used for treating heat entering nutrient-blood, toxic heat macula, hematemesis and epistaxis, conjunctival congestion, swelling and pain, liver depression, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal pain, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Cassia twig: has certain antibacterial and antiviral effects; has antipyretic, analgesic, tranquilizing, and anticonvulsive effects on central system; has obvious anti-inflammatory effect; can increase myocardial nutritional blood flow, and has antiallergic and anticoagulant effects. It is used to relieve exterior syndrome, warm meridians, unblock collaterals, strengthen yang to regulate qi, and smooth Chong and descend qi, and belongs to the category of pungent-warm exterior-syndrome-relieving herbs.
Clinical experiments are as follows:
the traditional Chinese medicine patch is selected for treatment, 50 cases are male, and 50 cases are female. Symptoms are: pain in the joints and difficulty in movement. Three treatment courses (10 days as one treatment course) are provided, and one patch is used for 1 day.
The curative effect standard is as follows:
and (3) healing: the clinical symptoms and physical signs of the traditional Chinese medicine disappear or basically disappear;
the effect is shown: the clinical symptoms and physical signs of the traditional Chinese medicine are obviously changed;
the method has the following advantages: the clinical symptoms and physical signs of the traditional Chinese medicine are improved;
and (4) invalidation: the clinical symptoms and physical signs of the traditional Chinese medicine are not obviously improved;
the results after the three treatment courses were: healing is 51; the effect is shown as 28; effective 18; and invalid 3. The result was 97% total effective rate.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (5)
1. A preparation method of a traditional Chinese medicine patch for arthralgia is characterized by comprising the following steps:
s1: preparing cortex Phellodendri, rhizoma Bletillae, radix Aconiti Kusnezoffii, radix Aristolochiae, rhizoma Cyperi, rhizoma Sparganii, herba Ephedrae, caulis Trachelospermi, rhizoma Drynariae, rhizoma Zingiberis recens, herba Menthae, herba Daturae, radix et rhizoma Rhei, rhizoma Polygoni Cuspidati, radix Paeoniae Rubra, ramulus Cinnamomi, Cera flava and Chinese liquor;
s2: drying the raw phellodendron, bletilla striata, raw kusnezoff monkshood root, the cow-bezoar, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig weighed in the step S1, and then putting the dried raw phellodendron, the bletilla striata, the raw kusnezoff monkshood root, the rhizoma cyperi, the rhizoma sparganii, the ephedra, the Chinese starjasmine stem, the rhizoma drynariae, the ginger, the mint, the stramonium, the rhubarb, the giant knotweed rhizome, the red paeony root and the cassia twig into a pulverizer to pulverize into powder for later use;
s3: adding the white spirit into the mixture obtained in the step S2, uniformly mixing, sealing and storing for 5-7 days;
s4: adding the substance stored in the step S3 into heated beeswax, mixing uniformly, cooling and shaping, and cutting into 10g blocks;
s5: the preparation of the Chinese medicinal patch for arthralgia was completed by wrapping 10g of each mixture of step S4 with a square patch having a side length of 10X 12 cm.
2. The method for preparing a traditional Chinese medicine patch for arthralgia according to claim 1, wherein the method comprises the following steps: the block mixture in the step S4 has a side length of 6 x 8 cm and a thickness of 0.2-0.3 cm.
3. The method for preparing a traditional Chinese medicine patch for arthralgia according to claim 1, wherein the method comprises the following steps: the powder of step S2 was sieved through a 400 mesh screen.
4. The method for preparing a traditional Chinese medicine patch for arthralgia according to claim 1, wherein the method comprises the following steps: according to the weight portion, the traditional Chinese medicine composition comprises 4-8 portions of the amur corktree bark, 3-5 portions of the bletilla striata, 4-6 portions of the kusnezoff monkshood root, 5-10 portions of the cowherb root, 2-5 portions of the nutgrass galingale rhizome, 2-5 portions of the common burreed rhizome, 3-6 portions of the ephedra herb, 1-4 portions of the Chinese starjasmine stem, 5-10 portions of the rhizoma drynariae, 2-5 portions of the ginger, 1-4 portions of the mint, 1-2 portions of the stramonium, 2-5 portions of the rhubarb, 4-8 portions of the giant knotweed rhizome, 4-8 portions of the red paeony root, 1-3 portions of the cassia twig, 10-15 portions of the beewax and 10-20 portions of the white spirit.
5. The method for preparing a Chinese medicinal patch for arthralgia according to claim 4, wherein the patch comprises: according to the weight portion, the traditional Chinese medicine composition comprises 5 portions of the amur corktree bark, 4 portions of the bletilla striata, 5 portions of the raw kusnezoff monkshood root, 8 portions of the cow-bezoar, 3 portions of the nutgrass galingale rhizome, 3 portions of the common burreed rhizome, 4 portions of the Chinese ephedra, 2 portions of the Chinese starjasmine stem, 6 portions of the rhizoma drynariae, 4 portions of the ginger, 2 portions of the mint, 1 portion of the stramonium, 4 portions of the rhubarb, 6 portions of the giant knotweed rhizome, 6 portions of the red paeony root, 2 portions of the cassia twig, 12 portions of the beewax and 15 portions of the white spirit.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107469007A (en) * | 2017-09-07 | 2017-12-15 | 成都兴倍加生物科技有限责任公司 | A kind of external used medicine for treating arthralgia and preparation method thereof |
| CN108478754A (en) * | 2018-07-09 | 2018-09-04 | 王清华 | It is a kind of to be used to treat Chinese medicine composition of bone joint pain and preparation method thereof |
| CN112755169A (en) * | 2021-03-11 | 2021-05-07 | 西安交通大学第二附属医院 | Traditional Chinese medicine plaster for treating rheumatic ostealgia |
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2021
- 2021-05-29 CN CN202110596012.5A patent/CN113304239A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107469007A (en) * | 2017-09-07 | 2017-12-15 | 成都兴倍加生物科技有限责任公司 | A kind of external used medicine for treating arthralgia and preparation method thereof |
| CN108478754A (en) * | 2018-07-09 | 2018-09-04 | 王清华 | It is a kind of to be used to treat Chinese medicine composition of bone joint pain and preparation method thereof |
| CN112755169A (en) * | 2021-03-11 | 2021-05-07 | 西安交通大学第二附属医院 | Traditional Chinese medicine plaster for treating rheumatic ostealgia |
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| Title |
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| 郭建生等: "《实用临床中药手册》", 31 August 2016, 湖南科学技术出版社 * |
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Application publication date: 20210827 |