CN113303974B - Method for manufacturing novel sterile pressure sore dressing - Google Patents

Method for manufacturing novel sterile pressure sore dressing Download PDF

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Publication number
CN113303974B
CN113303974B CN202110575465.XA CN202110575465A CN113303974B CN 113303974 B CN113303974 B CN 113303974B CN 202110575465 A CN202110575465 A CN 202110575465A CN 113303974 B CN113303974 B CN 113303974B
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hydrocolloid
wound
mixed
outer coating
mixed solution
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CN113303974A (en
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谢亚丽
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Tongji Medical College of Huazhong University of Science and Technology
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Tongji Medical College of Huazhong University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0203Adhesive plasters or dressings having a fluid handling member
    • A61F13/0213Adhesive plasters or dressings having a fluid handling member the fluid handling member being a layer of hydrocoloid, gel forming material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/00051Accessories for dressings
    • A61F13/00063Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0246Adhesive plasters or dressings characterised by the skin adhering layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0259Adhesive plasters or dressings characterised by the release liner covering the skin adhering layer
    • A61F13/0266Adhesive plasters or dressings characterised by the release liner covering the skin adhering layer especially adapted for wound covering/occlusive dressings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0289Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/40Afforestation or reforestation

Abstract

The invention discloses a novel sterile pressure sore dressing, which comprises an outer coating layer I, wherein a first adhesive tape is bonded on the top of the outer coating layer I, a replacing groove is formed in the outer coating layer I, a hydrocolloid is arranged in the replacing groove, an outer coating layer II is bonded on the bottom of the hydrocolloid, and a second adhesive tape is bonded on the top of the outer coating layer II; according to the invention, the mixed liquid of gelatin, glycerol and sodium bicarbonate is added into the hydrocolloid in the pressure sore dressing, so that the form of the hydrocolloid is changed, the hydrocolloid is in a fixed liquid form, the hydrocolloid can enter a wound of a patient and be contacted with the inner wall of the wound in a flowing manner, the contact between the hydrocolloid and the wound surface is increased, the inflammatory absorption is promoted, the recovery time of the wound of the patient is shortened, the sticky substance is removed, the hydrocolloid cannot be contacted with the wound of the patient and the skin around the wound, the pressure of the wound and the skin around the wound is further reduced, and the comfort of the patient in use is improved.

Description

Method for manufacturing novel sterile pressure sore dressing
Technical Field
The invention relates to the technical field of medical supplies, in particular to a manufacturing method of a novel sterile pressure sore dressing.
Background
The pressure sore dressing is a hydrocolloid dressing which is prepared by mixing elastic polymerized hydrogel, synthetic rubber and an adhesive and has the capability of absorbing wound seepage. After imbibing exudate, the hydrophilic particles in the dressing can form a gel-like semisolid substance which is attached to the base of a wound to provide and maintain a wet environment which is beneficial to wound healing.
The invention discloses an antibacterial hydrocolloid dressing and a preparation method thereof, as disclosed in patent CN104225663B, the antibacterial hydrocolloid dressing has limitation in use, after a pressure sore dressing is adhered to a wound of a patient, hydrocolloid cannot be contacted with the inner wall of the wound of the patient due to a solidified state, and hydrocolloid does not contact the inner wall of the wound, so that the use performance of hydrocolloid can be greatly influenced, inflammatory substances in hydrocolloid cannot be absorbed by the inner wall of the wound of the patient, the recovery of the wound of the patient is slow, the comfort of the patient in use of the pressure sore dressing can be greatly reduced by adhering the hydrocolloid to the wound of the patient and the skin around the wound for a long time, and when the pressure sore dressing is replaced by the patient, the pulling force of the pressure sore dressing when the pressure sore dressing is torn off can be increased by adhering the hydrocolloid to the wound of the patient and the skin around the wound of the patient for a long time, so that secondary wound of the patient can be easily caused, a pressure sore dressing capable of contacting the inner part of being capable of not sticking the patient and the skin around the wound can be stuck on the wound, and convenient to replace is provided to solve the problem.
Disclosure of Invention
The invention aims to provide a novel method for manufacturing a sterile pressure sore dressing, which aims to solve the problems that the pressure sore dressing cannot be contacted with the inner wall of a wound, can stick the wound of a patient and the skin around the wound and is inconvenient to replace when in use.
In order to achieve the purpose, the invention provides the following technical scheme:
novel aseptic pressure sore dressing, including overcoat layer one, the top bonding of overcoat layer one has paste and takes one, the change groove has been seted up to overcoat layer one's inside, the inside of changing the groove is equipped with hydrocolloid, hydrocolloid's bottom bonding has overcoat layer two, the top bonding of overcoat layer two has paste and takes two, paste the top of taking two and the bottom bonding of overcoat layer one.
Preferably, the top of the first outer coating layer is provided with a first anti-sticking layer and a second anti-sticking layer respectively, one side of the first anti-sticking layer is positioned on the top of the second anti-sticking layer, and the bottoms of the first anti-sticking layer and the second anti-sticking layer are both adhered to the top of the first adhesive tape.
Preferably, the width of the first anti-adhesion layer is the same as that of the second anti-adhesion layer, the length of the first anti-adhesion layer is smaller than that of the second anti-adhesion layer, and the sum of the lengths of the first anti-adhesion layer and the second anti-adhesion layer is longer than that of the first outer coating layer.
Preferably, the length and width of the first outer coating layer are the same as those of the second outer coating layer, and the first outer coating layer and the second outer coating layer are both made of medical-grade non-woven fabrics.
Preferably, the length and the width of the replacement groove are both larger than the length and the width of a hydrocolloid, and the shape of the hydrocolloid is a fixed liquid.
Preferably, the top of the first pasting belt and the top of the second pasting belt are both provided with adhesive layers, and the adhesive layers on the top of the first pasting belt and the top of the second pasting belt are specifically adhesives.
Preferably, after the second adhesive tape on the top of the first overcoat layer is adhered to the bottom of the first overcoat layer, the top of the second overcoat layer is not in contact with the bottom of the first overcoat layer.
Preferably, the top of the first adhesive tape is not contacted with the skin after the first adhesive tape is adhered with the skin.
Preferably, the first anti-sticking layer and the second anti-sticking layer are anti-sticking paper.
The manufacturing method of the novel sterile pressure sore dressing comprises the following steps:
the method comprises the following steps: processing a hydrogel material: according to the material proportion, firstly dissolving sodium hydroxide in water, then adding acrylic acid for pretreatment, after the pretreatment, sequentially adding corn starch, acrylamide and calcium carbonate, then stirring and heating, after the reaction is generated by stirring and heating, adding an initiator for graft polymerization reaction, and obtaining hydrogel mixed liquor after the reaction;
step two: treating a synthetic rubber material: taking rubber and paraffin oil, proportioning the rubber and the paraffin oil according to a proportion, adding a corresponding antioxidant according to the proportion requirement after proportioning, then heating at a high temperature, stirring the mixture in the heating process, and obtaining synthetic rubber liquid after the rubber is dissolved in the paraffin oil and is completely mixed with the antioxidant;
step three: manufacturing a contact layer: mixing gelatin, glycerol and sodium bicarbonate water according to a proportion, adding the sodium bicarbonate water after the gelatin and the glycerol are mixed, and then continuously stirring at a constant temperature until the gelatin, the glycerol and the sodium bicarbonate water are completely mixed to obtain a contact layer mixed solution;
step four: mixing: firstly, adding the hydrogel mixed solution into the contact layer mixed solution, then heating and stirring, adding the synthetic rubber mixture into the hydrogel mixed solution and the contact layer mixed solution after the hydrogel mixed solution and the contact layer mixed solution are completely mixed, and continuously heating and stirring until the three mixed solutions are completely mixed;
step five: and (3) cooling: and mixing the three mixed solutions to obtain a mixture, sealing, standing in a refrigerator for freezing for 10-12 hours, cooling, thawing at constant temperature for 10-12 hours, performing sterilization after thawing, and sterilizing to obtain the sterile pressure sore dressing plaster with a fixed liquid shape.
Compared with the prior art, the invention provides a manufacturing method of a novel sterile pressure sore dressing, which has the following beneficial effects:
according to the invention, by adding the mixed liquid of gelatin, glycerol and baking soda water into the hydrocolloid in the pressure sore dressing, the form of the hydrocolloid is changed, the hydrocolloid forms a fixed liquid form, and then the hydrocolloid can enter the wound of a patient and contact with the inner wall of the wound in a flowing manner, so that the contact between the hydrocolloid and the wound surface is increased, the inflammatory absorption is promoted, the recovery time of the wound of the patient is shortened, the sticky matter is removed, the hydrocolloid cannot contact with the wound of the patient and the skin around the wound, the pressure of the wound and the skin around the wound is further reduced, and the comfort of the patient in use is improved;
according to the invention, hydrocolloid is changed into solid liquid, the replacing groove is formed in the first outer coating layer, the hydrocolloid is combined with the second outer coating layer, the hydrocolloid is contacted with the wound of a patient, and the second outer coating layer is bonded with the first outer coating layer, so that the pressure sore dressing can be conveniently replaced by medical personnel, the first outer coating layer contacted with the skin of the patient can not be torn off by the medical personnel, the pain feeling of pulling cannot be generated when the pressure sore dressing is replaced by the patient, and the generation of secondary wound is reduced.
Drawings
FIG. 1 is a front view of the structure of the present invention;
FIG. 2 is a schematic view of the first release layer, the second release layer and the first adhesive tape of the present invention;
FIG. 3 is a schematic diagram of the replacement tank and hydrocolloid combination of the present invention;
FIG. 4 is a bottom schematic view of the overcoat of the present invention;
fig. 5 is a schematic view of the structure of the present invention in use with skin.
In the figure: 1. a first outer coating layer; 2. a first adhesive tape; 3. replacing the groove; 4. a hydrocolloid; 5. a second outer coating layer; 6. a second adhesive tape; 7. an anti-sticking layer I; 8. and an anti-sticking layer II.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1 to 5, the present invention provides a technical solution: the invention discloses a novel sterile pressure sore dressing, which comprises an outer coating layer 1, wherein an adhesive tape 2 is adhered to the top of the outer coating layer 1, a replacing groove 3 is formed in the outer coating layer 1, a hydrocolloid 4 is arranged in the replacing groove 3, an outer coating layer two 5 is adhered to the bottom of the hydrocolloid 4, an adhesive tape two 6 is adhered to the top of the outer coating layer two 5, and the top of the adhesive tape two 6 is adhered to the bottom of the outer coating layer 1.
Referring to fig. 1 and 2, the adhesive tape 2 can be used for preventing the adhesive tape from being adhered to a contact object and sealing the hydrocolloid 4, a first anti-sticking layer 7 and a second anti-sticking layer 8 are respectively arranged on the top of the first outer coating layer 1, one side of the first anti-sticking layer 7 is positioned on the top of the second anti-sticking layer 8, and the bottoms of the first anti-sticking layer 7 and the second anti-sticking layer 8 are both adhered to the top of the first adhesive tape 2.
Please refer to fig. 1 and fig. 2, which is convenient for the medical staff to stick to the patient, so that the fingers of the medical staff can not directly contact with the first sticking belt 2 when sticking, the width of the first anti-sticking layer 7 is the same as that of the second anti-sticking layer 8, the length of the first anti-sticking layer 7 is smaller than that of the second anti-sticking layer 8, and the sum of the length of the first anti-sticking layer 7 and the second anti-sticking layer 8 is longer than that of the first outer coating layer 1.
Referring to fig. 1, 2 and 3, the surface of the hydrocolloid 4 and the inner part of the replacement groove 3 are conveniently sleeved, so that medical staff can determine whether the position of the hydrocolloid 4 is correct when pasting the hydrocolloid on a patient, the length and the width of the first outer coating layer 1 are the same as those of the second outer coating layer 5, and the first outer coating layer 1 and the second outer coating layer 5 are both made of medical-grade non-woven fabrics.
Referring to fig. 2 and 3, the contact between the hydrocolloid 4 and the inner wall of the replacement groove 3 is avoided, and the hydrocolloid 4 can flow into the wound of the patient, the length and width of the replacement groove 3 are both greater than those of the hydrocolloid 4, and the shape of the hydrocolloid 4 is specifically a fixed liquid.
Referring to fig. 2 and 3, for improving the connectivity between the first adhesive tape 2 and the second adhesive tape 6, and for improving the sealing and connectivity between the first adhesive tape 2 and the skin of the patient, the adhesive layers are disposed on the top of the first adhesive tape 2 and the top of the second adhesive tape 6, and the adhesive layers on the top of the first adhesive tape 2 and the top of the second adhesive tape 6 are specifically adhesives.
Referring to fig. 2, the hydrocolloid 4 is easily torn off, so that the medical staff can directly tear off the second overcoating layer 5 when changing the hydrocolloid 4, and the change of the hydrocolloid 4 is further easily performed, and after the second adhesive tape 6 on the top of the second overcoating layer 5 is adhered to the bottom of the first overcoating layer 1, the top of the second overcoating layer 5 is not in contact with the bottom of the first overcoating layer 1.
Referring to fig. 5, the overcoat layer 1 is easily removed by medical staff, and the top of the adhesive tape 2 is adhered to the skin, so that the overcoat layer 1 does not contact the skin.
Referring to fig. 1 and 2, for preventing water and oil stains, the first release layer 7 and the second release layer 8 are release paper.
The manufacturing method of the novel sterile pressure sore dressing comprises the following steps:
the method comprises the following steps: processing a hydrogel material: according to the material proportion, firstly dissolving sodium hydroxide in water, then adding acrylic acid for pretreatment, after the pretreatment, sequentially adding corn starch, acrylamide and calcium carbonate, then stirring and heating, after the reaction is generated by stirring and heating, adding an initiator for graft polymerization reaction, and obtaining hydrogel mixed liquor after the reaction;
step two: processing the synthetic rubber material: taking rubber and paraffin oil, proportioning the rubber and the paraffin oil according to a proportion, adding a corresponding antioxidant according to the proportion requirement after proportioning, then heating at a high temperature, stirring the mixture in the heating process, and obtaining synthetic rubber liquid after the rubber is dissolved in the paraffin oil and is completely mixed with the antioxidant;
step three: manufacturing a contact layer: mixing gelatin, glycerol and sodium bicarbonate according to a proportion, adding the sodium bicarbonate after the gelatin and the glycerol are mixed, and then continuously stirring at a constant temperature until the gelatin, the glycerol and the sodium bicarbonate are completely mixed to obtain a contact layer mixed solution;
step four: mixing: firstly, adding the hydrogel mixed solution into the contact layer mixed solution, then heating and stirring, adding the synthetic rubber mixture into the hydrogel mixed solution and the contact layer mixed solution after the hydrogel mixed solution and the contact layer mixed solution are completely mixed, and continuously heating and stirring until the three mixed solutions are completely mixed;
step five: and (3) cooling: and mixing the three mixed solutions to obtain a mixture, sealing, standing in a refrigerator for freezing for 10-12 hours, cooling, thawing at constant temperature for 10-12 hours, performing sterilization after thawing, and sterilizing to obtain the sterile pressure sore dressing plaster with a fixed liquid shape.
The working principle is as follows: when the adhesive tape is used, the first anti-sticking layer 7 on the top of the first outer coating layer 1 is torn off, the first adhesive tape 2 on the top of the first outer coating layer 1 is exposed, then the first adhesive tape 2 is adhered to the skin of a patient, then the second anti-sticking layer 8 is torn off, and in the process of tearing off the second anti-sticking layer 8, the remaining first adhesive tape 2 is adhered to the skin of the patient in a pulling mode along with the exposure of the remaining first adhesive tape 2, the hydrocolloid 4 in a solid liquid state flows into the wound of the patient after adhesion, and then the hydrocolloid 4 is contacted with the inside of the wound of the patient, so that the purpose of absorbing the inner wall of the wound is achieved;
when the hydrocolloid 4 needs to be replaced, the first outer coating layer 1 can be held by hand, the second outer coating layer 5 is slowly pulled, the second outer coating layer 5 drives the hydrocolloid 4 to be separated from the skin and the inner wall of a wound of a patient, after the second outer coating layer 5 is completely torn off, the new hydrocolloid 4 is aligned with the replacement groove 3, and after the new hydrocolloid 4 is aligned, the second adhesive tape 6 on the top of the second outer coating layer 5 is adhered to the first outer coating layer 1, so that the purpose of facilitating replacement is achieved.
It should be noted that, in this document, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising a … …" does not exclude the presence of another identical element in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (1)

1. The manufacturing method of the novel sterile pressure sore dressing is characterized by comprising the following steps:
the method comprises the following steps: processing a hydrogel material: according to the material proportion, firstly dissolving sodium hydroxide in water, then adding acrylic acid for pretreatment, after the pretreatment, sequentially adding corn starch, acrylamide and calcium carbonate, then stirring and heating, after the reaction is generated by stirring and heating, adding an initiator for graft polymerization reaction, and obtaining hydrogel mixed liquor after the reaction;
step two: treating a synthetic rubber material: taking rubber and paraffin oil, proportioning the rubber and the paraffin oil according to a proportion, adding a corresponding antioxidant according to the proportion requirement after proportioning, then heating at a high temperature, stirring the mixture in the heating process, and obtaining synthetic rubber liquid after the rubber is dissolved in the paraffin oil and is completely mixed with the antioxidant;
step three: manufacturing a contact layer: mixing gelatin, glycerol and sodium bicarbonate water according to a proportion, adding the sodium bicarbonate water after the gelatin and the glycerol are mixed, and then continuously stirring at a constant temperature until the gelatin, the glycerol and the sodium bicarbonate water are completely mixed to obtain a contact layer mixed solution;
step four: mixing: firstly adding the hydrogel mixed solution into the contact layer mixed solution, then heating and stirring, adding the synthetic rubber mixture into the hydrogel mixed solution and the contact layer mixed solution after the hydrogel mixed solution and the contact layer mixed solution are completely mixed, and continuously heating and stirring until the three mixed solutions are completely mixed;
step five: and (3) cooling: and mixing the three mixed solutions to obtain a mixture, sealing, standing in a refrigerator for freezing for 10-12 hours, cooling, thawing at constant temperature for 10-12 hours, performing sterilization after thawing, and sterilizing to obtain the sterile pressure sore dressing plaster with a fixed liquid shape.
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Citations (1)

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