CN113288959A - Traditional Chinese medicine sachet for preventing influenza and preparation method thereof - Google Patents

Traditional Chinese medicine sachet for preventing influenza and preparation method thereof Download PDF

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CN113288959A
CN113288959A CN202110698356.7A CN202110698356A CN113288959A CN 113288959 A CN113288959 A CN 113288959A CN 202110698356 A CN202110698356 A CN 202110698356A CN 113288959 A CN113288959 A CN 113288959A
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chinese medicine
traditional chinese
medicine sachet
sachet
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刘芳
孙庆
逄妍
海兴华
谭莹
潘建鸿
靳丽
王莉
李晓雯
宋华隆
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FIRST AFFILIATED HOSPITAL OF TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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FIRST AFFILIATED HOSPITAL OF TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K9/009Sachets, pouches characterised by the material or function of the envelope
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    • A61P11/00Drugs for disorders of the respiratory system
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    • A61P11/02Nasal agents, e.g. decongestants
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses

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Abstract

The invention relates to the technical field of traditional Chinese medicine sachets, and discloses a traditional Chinese medicine sachet for preventing influenza, which is prepared from the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 5-20 parts of astragalus membranaceus and 3-15 parts of divaricate saposhnikovia root. A preparation method of a traditional Chinese medicine sachet for preventing influenza mainly comprises the following steps: the first step is as follows: respectively weighing the raw materials, mixing, crushing and sieving by a 100-mesh sieve to obtain powdery traditional Chinese medicine fine powder; the second step is that: putting the obtained traditional Chinese medicine fine powder into a breathable non-woven fabric bag, and sealing to obtain a traditional Chinese medicine sachet; the third step: sealing the prepared traditional Chinese medicine sachet with a sealed plastic film. The traditional Chinese medicine sachet has the effects of preventing influenza and relieving the symptoms of nasal obstruction and rhinorrhea caused by cold.

Description

Traditional Chinese medicine sachet for preventing influenza and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine sachets, in particular to a traditional Chinese medicine sachet for preventing influenza and a preparation method thereof.
Background
The sachet is a common decoration in people's life, has a long history, and has records of using fragrant medicines to prevent epidemic as early as thousands of years, and is widely applied to the period of Qin and Han dynasties. Research shows that the traditional Chinese medicine sachet has the function of stimulating the respiratory mucosa of a human body to generate secretory immunoglobulin by continuously releasing aromatic odor, has stronger killing effect on viruses and bacteria, and thus has stronger effect of preventing infectious diseases. However, the components of the prior sachet in the market are uneven, the curative effect is uncertain, and the medication quality can not be ensured.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide the traditional Chinese medicine sachet for preventing influenza and the preparation method thereof, wherein the traditional Chinese medicine sachet has the functions of preventing influenza and relieving the symptoms of nasal obstruction and rhinorrhea caused by cold.
The invention is realized by adopting the following technical scheme: a traditional Chinese medicine sachet for preventing influenza is prepared by filling the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis and 1-10 parts of asarum.
Furthermore, the traditional Chinese medicine sachet is also filled with the following raw material medicines: comprises radix astragali and radix Saposhnikoviae.
Further, the traditional Chinese medicine sachet for preventing influenza is prepared from the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 5-20 parts of astragalus membranaceus and 3-15 parts of divaricate saposhnikovia root.
A traditional Chinese medicine sachet for preventing influenza is prepared from the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 3-10 parts of cocklebur fruit and 3-10 parts of magnolia flower.
A preparation method of a traditional Chinese medicine sachet for preventing influenza mainly comprises the following steps:
the first step is as follows: respectively weighing the raw materials, mixing, crushing and sieving by a 100-mesh sieve to obtain powdery traditional Chinese medicine fine powder;
the second step is that: putting the obtained traditional Chinese medicine fine powder into a breathable non-woven fabric bag, and sealing to obtain a traditional Chinese medicine sachet;
the third step: sealing the prepared traditional Chinese medicine sachet with a sealed plastic film.
Compared with the prior art, the invention has the beneficial effects that: the traditional Chinese medicine sachet for preventing influenza is prepared by crushing and mixing eleven traditional Chinese medicines of agastache rugosus, clove, elecampane, notopterygium root, angelica dahurica, radix bupleuri, calamus, rhizoma atractylodis, asarum, astragalus mongholicus and radix sileris according to a proportion, has a certain effect on preventing common cold and influenza and has a certain promotion effect on recovery of cold. The Chinese medicinal composition is prepared by crushing and mixing eleven Chinese medicaments of agastache rugosus, clove, costustoot, notopterygium root, angelica dahurica, radix bupleuri, calamus, rhizoma atractylodis, asarum, cocklebur fruit and biond magnolia flower in proportion, has a promoting effect on recovery of cold, and can obviously relieve nasal obstruction and rhinorrhea symptoms caused by cold.
Detailed Description
The present invention is further described below with reference to specific embodiments, and it should be noted that, without conflict, any combination between the embodiments or technical features described below may form a new embodiment.
Example 1
The invention relates to a traditional Chinese medicine sachet for preventing influenza, which is prepared from the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 5-20 parts of astragalus membranaceus and 3-15 parts of divaricate saposhnikovia root.
The preparation method of the traditional Chinese medicine sachet for preventing influenza comprises the following steps:
the first step is as follows: respectively weighing the raw materials, mixing, crushing and sieving by a 100-mesh sieve to obtain powdery traditional Chinese medicine fine powder;
the second step is that: putting the obtained traditional Chinese medicine fine powder into a breathable non-woven fabric bag, and sealing to obtain a traditional Chinese medicine sachet;
the third step: the prepared traditional Chinese medicine sachet is sealed by a sealed plastic film, so that the storage time of the sachet can be prolonged. When in use, the sealing plastic film on the outer surface is torn off, so that the fragrance of the traditional Chinese medicine sachet is slowly emitted.
The herba Agastaches has pungent taste and mild nature, and has effects of relieving summer-heat, eliminating dampness, and relieving vomit. Modern pharmacological research shows that the traditional Chinese medicine composition has the functions of easing pain, stopping vomiting, calming, promoting gastrointestinal peristalsis, enhancing gastrointestinal absorption and the like. Clove is pungent in flavor and warm in nature, and has the effects of warming the middle-jiao, lowering the adverse flow of qi, warming the kidney and tonifying yang. Modern pharmacological research shows that the product has the effects of resisting oxidation, sterilizing, relieving fever and pain, and the like. Radix aucklandiae is pungent and bitter in flavor and warm in nature, and has the effects of promoting qi circulation, relieving pain, invigorating spleen and promoting digestion. Modern pharmacological research shows that the compound has the effects of resisting inflammation, resisting tumor, benefiting gallbladder, resisting gastric ulcer and the like. Notopterygium root, rhizoma Et radix Notopterygii, being sweet, pungent and bitter in flavor and warm in nature, has the effects of relieving exterior syndrome, dispelling cold, expelling wind, removing dampness and alleviating pain. Modern pharmacological research shows that the medicine has the functions of relieving fever and pain, resisting bacteria, resisting arrhythmia and the like. Radix Angelicae Dahuricae is pungent in flavor and warm in nature, and has effects of relieving exterior syndrome, dispelling cold, inducing resuscitation, relieving pain, eliminating dampness, stopping leukorrhagia, and relieving swelling and pus discharge. Modern pharmacological research shows that the traditional Chinese medicine composition has the effects of relieving fever, relieving spasm, easing pain, relieving asthma, reducing blood pressure and the like. Radix bupleuri is bitter and pungent in flavor and slightly cold in nature, and can disperse and abate fever, sooth liver and relieve depression, raise yang and lift sinking, clear gallbladder and check malaria. Modern pharmacological research shows that the medicine has the effects of relieving fever, resisting inflammation, protecting liver, resisting bacteria and the like. Rhizoma Acori Graminei is bitter and pungent in taste and warm in nature, and has effects of eliminating dampness, promoting appetite, inducing resuscitation, eliminating phlegm, refreshing mind and improving intelligence. Modern pharmacological research shows that the medicine has the effects of central sedation, convulsion resistance and the like. Cang Zhu is pungent and bitter in flavor and warm in nature, and enters spleen and stomach meridians. Has the effects of strengthening spleen, eliminating dampness, relieving depression and removing dirt. Modern pharmacological research shows that the traditional Chinese medicine composition has the effects of regulating gastrointestinal motility, resisting ulcer and the like. The asarum is pungent in flavor and warm in nature, and has the effects of relieving exterior syndrome, dispelling cold, dispelling wind, relieving pain, dredging orifices, warming lung and resolving fluid retention. Modern pharmacological research shows that the traditional Chinese medicine composition has the effects of relieving fever, calming, easing pain, resisting inflammation, resisting allergic reaction, relaxing bronchial smooth muscle and the like. The medicated bag has effects of invigorating spleen, invigorating qi, dispelling pathogenic wind, consolidating superficial resistance, and preventing influenza by adding radix astragali and radix Saposhnikoviae.
The traditional Chinese medicine sachet for preventing influenza is subjected to small-sample clinical observation and test. Randomly selecting 50 healthy subjects of 18-60 years old in good flu season from 11 months to 3 months, 2020, 2019, and each person gives 8 traditional Chinese medicine sachets for preventing flu, wherein the sachets are required to be worn in front of the chest for not less than 8 hours every day, the sachets are replaced every 3-4 days, and the observation time is 4 weeks. Follow-up visits were made to the subjects after 4 weeks, and the results showed that 48 subjects did not develop cold symptoms such as aversion to cold, fever, nasal obstruction, watery nasal discharge, and cough; the 2 subjects had cold symptoms during the observation period, the average remission time was 5.5 days, and the total effective rate of the influenza-preventing sachet to prevent cold was 96%. The test result proves that the traditional Chinese medicine sachet for preventing influenza has certain effect on preventing common cold and influenza, the average remission time of a subject suffering from the cold is obviously shorter than the average course of the cold (7-10 days), and the sachet has the effect of promoting the recovery of the cold.
Example 2
The invention relates to a traditional Chinese medicine sachet for preventing influenza, which is prepared from the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 3-10 parts of cocklebur fruit and 3-10 parts of magnolia flower. The fructus xanthil and the flos magnoliae have the effects of dispelling cold, relieving exterior syndrome and dredging nasal orifices, and have better effects on improving symptoms such as nasal obstruction, rhinorrhoea and the like caused by common cold and influenza.
The preparation method of the traditional Chinese medicine sachet for preventing influenza comprises the following steps:
the first step is as follows: respectively weighing the raw materials, mixing, crushing and sieving by a 100-mesh sieve to obtain powdery traditional Chinese medicine fine powder;
the second step is that: putting the obtained traditional Chinese medicine fine powder into a breathable non-woven fabric bag, and sealing to obtain a traditional Chinese medicine sachet;
the third step: the prepared traditional Chinese medicine sachet is sealed by a sealed plastic film, so that the storage time of the sachet can be prolonged. When in use, the sealing plastic film on the outer surface is torn off, so that the fragrance of the traditional Chinese medicine sachet is slowly emitted.
The traditional Chinese medicine sachet for preventing influenza is subjected to small-sample clinical observation and test. 30 subjects with cold symptoms of aversion to cold, fever, nasal obstruction, watery nasal discharge, cough and the like in 18-60 years old are randomly selected in good flu season from 11 months to 3 months, 2020, 2019, and on the basis that the subjects take basic cold treatment medicines according to the illness state, each person releases 8 traditional Chinese medicine sachets for preventing flu, the sachets are required to be worn in front of the chest for not less than 8 hours every day, the sachets are replaced every 3-4 days, and the observation time is 4 weeks. The follow-up visit is carried out on the subjects after 4 weeks, and the results show that the average relieving time of the cold symptoms of 30 subjects is 5.7 days, and the cold symptom repeated condition does not occur after the relief; after 26 subjects wear the sachet for 1 day, the symptoms of nasal obstruction and nasal discharge are relieved, and the relieving rate is 86.7%. The average relieving time of the cold of the subject in the test is obviously shorter than the average course of the cold (7-10 days), which proves that the traditional Chinese medicine sachet for preventing the cold has the function of promoting the recovery of the cold and can obviously relieve the symptoms of nasal obstruction and rhinorrhea caused by the cold.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (6)

1. The traditional Chinese medicine sachet for preventing influenza is characterized in that the traditional Chinese medicine sachet is filled with the following raw material medicines in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis and 1-10 parts of asarum.
2. The traditional Chinese medicine sachet for preventing influenza, which is characterized in that the traditional Chinese medicine sachet is filled with the following raw materials: comprises radix astragali and radix Saposhnikoviae.
3. The traditional Chinese medicine sachet for preventing influenza, which is characterized by comprising the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 5-20 parts of astragalus membranaceus and 3-15 parts of divaricate saposhnikovia root.
4. The traditional Chinese medicine sachet for preventing influenza, which is characterized in that the traditional Chinese medicine sachet is filled with the following raw materials: comprises fructus Xanthii and flos Magnoliae.
5. The traditional Chinese medicine sachet for preventing influenza, which is characterized by comprising the following raw materials in parts by weight: 3-10 parts of agastache rugosus, 3-10 parts of clove, 3-15 parts of costus root, 3-10 parts of notopterygium root, 5-20 parts of angelica dahurica, 3-10 parts of radix bupleuri, 5-20 parts of rhizoma acori graminei, 10-30 parts of rhizoma atractylodis, 1-10 parts of asarum, 3-10 parts of cocklebur fruit and 3-10 parts of magnolia flower.
6. The preparation method of the traditional Chinese medicine sachet for preventing influenza as claimed in any one of claims 1 to 5, which is characterized by comprising the following main steps:
the first step is as follows: respectively weighing the raw materials, mixing, crushing and sieving by a 100-mesh sieve to obtain powdery traditional Chinese medicine fine powder;
the second step is that: putting the obtained traditional Chinese medicine fine powder into a breathable non-woven fabric bag, and sealing to obtain a traditional Chinese medicine sachet;
the third step: sealing the prepared traditional Chinese medicine sachet with a sealed plastic film.
CN202110698356.7A 2021-06-23 2021-06-23 Traditional Chinese medicine sachet for preventing influenza and preparation method thereof Pending CN113288959A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114470077A (en) * 2022-01-12 2022-05-13 贵州中医药大学 Medicine for treating wind-cold type common cold and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103070996A (en) * 2012-11-21 2013-05-01 徐曼丽 Traditional Chinese medicine sachet used for preventing and treating influenza
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Application publication date: 20210824