CN113252659A - Detection platform and detection kit - Google Patents

Detection platform and detection kit Download PDF

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Publication number
CN113252659A
CN113252659A CN202110759751.1A CN202110759751A CN113252659A CN 113252659 A CN113252659 A CN 113252659A CN 202110759751 A CN202110759751 A CN 202110759751A CN 113252659 A CN113252659 A CN 113252659A
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China
Prior art keywords
detection
platform
holding tank
testing
storage
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Granted
Application number
CN202110759751.1A
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Chinese (zh)
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CN113252659B (en
Inventor
熊正
潘丰阳
杜明艺
董昭贵
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Guangzhou Wondfo Biotech Co Ltd
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Guangzhou Wondfo Biotech Co Ltd
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Priority to CN202110759751.1A priority Critical patent/CN113252659B/en
Publication of CN113252659A publication Critical patent/CN113252659A/en
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Publication of CN113252659B publication Critical patent/CN113252659B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/02Laboratory benches or tables; Fittings therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor

Abstract

The invention belongs to the field of sample detection, and discloses a detection platform and a detection kit. Wherein, testing platform includes operation side and support side, the operation side with there is the difference in height in the support side, the operation side is provided with detection area and storage area, detection area is provided with the detection groove of undercut, storage area is provided with sunken storage bit, detection groove with the storage bit is independent each other, the storage bit includes first holding tank and second holding tank, the second holding tank is rectangular shape, be provided with the breach on the second holding tank, the breach is in second holding tank width direction is last size to be greater than the second holding tank width. The partition processing is carried out, the articles are placed neatly, the operation steps are reduced, and the detection process is accelerated.

Description

Detection platform and detection kit
Technical Field
The invention belongs to the field of sample detection, and particularly relates to a detection platform and a detection kit.
Background
The sample detection is widely used in daily life, such as detection of pesticide residue in food, detection of medical samples, and detection steps generally include collecting a sample to be detected, then making into a sample liquid to be detected, and finally performing detection. For example, the method can be used for detecting infectious diseases of respiratory tracts by adopting a colloidal gold immunoassay method, and a colloidal gold immunoassay reagent box and a special eluent placing bottle are required. During detection, a sample is collected by using a sample collecting device; then opening the placing bottle, placing the sample into the placing bottle, closing the placing bottle, shaking, and eluting the sample; then taking out the colloidal gold immunoassay reagent card box, placing the card box on a plane, opening the placing bottle again, taking out the eluent containing the sample, dripping the eluent on the card box, and then closing the placing bottle; and finally, waiting for the testing time, and checking the detection result of the colloidal gold immunoassay reagent card box. This process requires multiple openings and closings of the bottle, resulting in a complex operation. And all parts of the detection product are dispersedly filled into a packaging box or a packaging bag and are easy to scatter after being opened.
At present, the colloidal gold immunoassay product can be provided for professional medical detection personnel to quickly detect and screen diseases, and can also be provided for household self-inspection of common people due to the rapidity of detection and considering the requirement of large-area screening of infectious diseases such as some respiratory infectious diseases. Therefore, the convenience of product operation and the reduction of detection cost are problems which need to be solved urgently.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide a detection platform and a detection kit, which are used for processing in a partitioning manner, neatly placing articles, reducing operation steps and accelerating a detection process.
The technical scheme is as follows:
the detection platform comprises an operation side and a supporting side, wherein the operation side and the supporting side have a height difference, the operation side is provided with a detection area and a storage area, the detection area is provided with a detection groove which is sunken downwards, the storage area is provided with a sunken storage position, and the detection groove and the storage position are mutually independent.
In one embodiment, the storage bit includes a first storage slot and a second storage slot.
In one embodiment, the second storage groove is in a long strip shape, and a gap is arranged on the second storage groove, and the size of the gap in the width direction of the second storage groove is larger than the width of the second storage groove.
In one embodiment, the depth of the second reservoir is less than the depth of the gap.
In one embodiment, the inner surface of the detection groove is provided with a convex part.
In one embodiment, the protrusions are provided on the bottom and/or side walls of the detection slot.
In one embodiment, the detection area is further provided with a receiving position, and the receiving position extends to the detection groove.
In one embodiment, the receiving position comprises a receiving plane, and the receiving plane is arranged at an angle of 0-80 degrees with the upper surface of the operation side.
In one embodiment, the detection grooves and the receiving positions are provided in plurality, each detection groove is independently provided, and each detection groove corresponds to each receiving position in a one-to-one manner.
A test kit comprising an eluent, a sampler, a test strip, and the test platform of claim 1; and during packaging, the eluent, the sampler and the detection test paper are all placed on the storage bit.
The technical scheme provided by the invention has the following advantages and effects:
during detection, the supporting side is used for supporting the detection platform, the operation side is upward at the moment, the eluent is dripped into different detection grooves, a sampler is used for collecting samples and inserting the samples into the detection grooves containing the eluent, the samples are taken out after elution is finished, then the sample adding side of the detection test paper is inserted into the detection grooves, the sample adding is completed after the detection test paper is contacted with the eluent, and a test result waiting is placed. In the testing process, saved the eluant and closed repeatedly and opened the bottle of placing, also saved the time in the operation greatly, moreover because the application of sample process is accomplished on testing platform, can directly adopt test paper, compare in the mode that adopts reagent card box, saved the material cost, so not only operate more simply in this scheme, saved manufacturing cost moreover. In addition, the independently arranged storage positions are used for placing the eluent, the sampler, the detection test paper, the specification and the like, and then are wrapped by outer packages or sealed by plastic bags, so that the overall space of the package is saved, and after the storage positions are taken out, the eluent, the sampler, the detection test paper, the specification and the like are orderly placed.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and, together with the description, serve to explain the principles and effects of the invention.
Unless otherwise specified or defined, the same reference numerals in different figures refer to the same or similar features, and different reference numerals may be used for the same or similar features.
FIG. 1 is an exploded view of a test kit according to an embodiment of the present invention;
FIG. 2 is a schematic top view of an inspection platform according to an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of a sampler according to an embodiment of the present invention during elution;
FIG. 4 is a schematic cross-sectional view of a test strip according to an embodiment of the present invention;
fig. 5 is an enlarged schematic view of the embodiment of the present invention at a in fig. 1.
Description of reference numerals:
10. an operating side; 11. a detection tank; 111. a boss portion; 12. carrying out carrying position; 121. carrying a plane; 20. a support side; 21. storing bits; 211. a first storage tank; 212. a second storage tank; 213. a notch; 30. eluting the solution; 40. a sampler; 50. detecting test paper; 60. and (6) instructions.
Detailed Description
In order to facilitate an understanding of the invention, specific embodiments thereof will be described in more detail below with reference to the accompanying drawings.
Unless specifically stated or otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In the case of combining the technical solutions of the present invention in a realistic scenario, all technical and scientific terms used herein may also have meanings corresponding to the purpose of achieving the technical solutions of the present invention.
As used herein, unless otherwise specified or defined, "first" and "second" … are used merely for name differentiation and do not denote any particular quantity or order.
As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items, unless specified or otherwise defined.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly secured to the other element or intervening elements may also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present; when an element is referred to as being "mounted on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "on" another element, it can be directly on the other element or intervening elements may also be present.
As shown in fig. 1 to 4, the detection kit comprises an eluent 30, a sampler 40, a test strip 50 and the detection platform; the eluant 30, sampler 40, test strip 50, and instructions 60 are placed on the storage location 21 during packaging. In use, the sampler 40 is used to collect a test sample; the eluent 30 can be placed in the detection tank 11 and used for eluting the collected sample on the sampler 40; the test strip 50 is used to detect the sample in the eluate 30. Wherein the sampler 40 is a swab in this embodiment, and the eluent 30 is packaged in a disposable manner.
As shown in fig. 1 and 2, the detection platform includes an operation side 10 and a support side 20, the operation side 10 and the support side 20 have a height difference, the operation side 10 is provided with a detection area and a storage area, the detection area is provided with a detection groove 11 which is recessed downwards, the storage area is provided with a storage location 21 which is recessed, and the detection groove 11 and the storage location 21 are independent from each other.
As shown in fig. 1 to 4, during detection, the supporting side 20 is used for supporting the detection platform, and the operation side 10 is upward at this time, the eluent 30 is dropped into different detection slots 11, the sample collected by the sampler 40 is inserted into the detection slot 11 containing the eluent 30, the sample is taken out after the elution is completed, the sample adding side of the detection test paper 50 is inserted into the detection slot 11, and the detection test paper 50 is placed after the sample is added to wait for the test result. In the testing process, saved the eluant 30 and closed repeatedly and opened the bottle of placing, also saved the time in operation greatly, moreover because the application of sample process is accomplished on testing platform, can directly adopt test paper 50, compare in the mode that adopts reagent card box, saved the material cost, so not only operate more simply in this scheme, but also saved manufacturing cost. In addition, the storage position 21 which is separately arranged is used for placing the eluent 30, the sampler 40, the detection test paper 50, the instruction book 60 and the like, and then the eluent is wrapped by an outer package or sealed by a plastic bag, so that the whole packaging space is saved, and the eluent 30, the sampler 40, the detection test paper 50, the instruction book 60 and the like are orderly placed after being taken out.
The operation side 10 is an upper surface of an inspection platform in the present embodiment, and a concave inspection groove 11 is formed on the upper surface; the supporting side 20 may be the bottom of the detection slot 11, or the outer edge of the detection platform, i.e. the bottom of the detection platform, for supporting. The height difference between the operation side 10 and the support side 20 is at least greater than the depth dimension of the detection slot 11.
As shown in fig. 1 and 2, the storage bit 21 includes a first storage slot 211 and a second storage slot 212. The test paper 50 can be stored in the second storage groove 212 separately, and the most core test paper in the detection process is the test paper 50, so that the test paper 50 is prevented from being taken out when the specification 60 and the sampler 40 are taken out, even the test paper is taken out and lost along the specification 60 because the test paper is included in the specification 60, and the second storage groove 212 is provided for storing the test paper 50, so that the test paper 50 can be prevented from being lost, and the test paper 50 can be taken out separately conveniently.
As shown in fig. 1 and 2, the second storage groove 212 is in a long strip shape, a gap 213 is arranged on the second storage groove 212, the size of the gap 213 in the width direction of the second storage groove 212 is larger than the width of the second storage groove 212, and the size of the gap 213 in the length direction of the second storage groove 212 is not smaller than one centimeter. The second storage groove 212 is in a shape of a strip adapted to 50 test strips, and after the test strips are placed in the second storage groove 212, the shapes of the test strips are approximately the same, so that the positions of the 50 test strips are relatively fixed. When 50 test paper strips need to be taken out, the human fingers cannot directly stretch into the narrow space of the second storage tank, and the 50 test paper strips are difficult to take out, so that the notch 213 is specially formed, the fingers of people can be accommodated and stretch into the second storage tank 212, and the test paper 50 is taken out. The size of the notch 213 is suitable for the size of a human finger, so that the finger can extend into the notch 213.
In this embodiment, the opening of the notch 213 involves two side walls in the width direction of the second storage slot 212, and since the tip of a finger of a person is hard to grasp, the notch 213 is opened at two sides of the second storage slot 212, one side is used for stretching and the other side is used for avoiding the finger tip, so that the finger abdomen of the finger can stretch into the second storage slot 212.
As shown in fig. 5, the depth of the second storage groove 212 is smaller than the depth of the notch 213. After the test paper 50 is placed in the second storage groove 212, since the depth of the second storage groove 212 is less than that of the notch 213, a gap exists below the second storage groove 212, so that the test paper 50 placed in the second storage groove 212 is above the gap, and when a person takes out the test paper 50, the gap is used for conveniently taking out the test paper 50.
As shown in fig. 2 to 3, the inner surface of the detection groove 11 is provided with a convex portion 111. When the sample is eluted, the sample is directly soaked in the eluent 30, the elution effect is not ideal, and the sampler 40 is scraped on the convex part 111 through the arrangement of the convex part 111, so that the sample is scraped, and the elution effect is obviously improved.
The protrusions 111 are provided on the bottom and/or the side walls of the detection tank 11. As shown in fig. 3, is specifically disposed at the bottom of the detection tank 11. The bottom of the sampler 40 scratches back and forth at the bottom of the detection groove 11, and the sample is scraped under the action of the convex part 111.
As shown in fig. 1 to 4, the detection area is further provided with a receiving position 12, and the receiving position 12 extends to the detection groove 11. The receiving position 12 includes a receiving plane 121, and the receiving plane 121 is disposed at an angle of 0 to 80 degrees with respect to the upper surface of the operation side 10. The receiving plane 121 or an extension line thereof extends below the detection slot 11. The receiving plane 121 or an extension line thereof extends below the detection slot 11. The bearing surface is used for placing the detection test paper 50, and the detection test paper 50 is in a strip shape, can be attached to the bearing plane 121 to be placed, and is used for reading and avoiding the random movement of the detection test paper 50. Specifically, the receiving plane 121 and the upper surface of the operation side 10 may be parallel or inclined, that is, the receiving plane 121 and the upper surface of the operation side 10 may be arranged at an angle of 0 to 80 degrees; a preferred angle is 15 to 25 degrees, in particular in the present embodiment the angle is provided with 18 degrees.
When the test paper is parallel, the receiving plane 121 penetrates through the detection tank 11, but is higher than the highest liquid level of the detection tank 11 after the eluent 30 is placed in the eluent 30, so that the eluent 30 is prevented from entering the receiving plane 121, and further the whole receiving plane 121 is covered, so that the sample washing of the test paper 50 can be caused, and the detection result is influenced, in this case, after the test paper 50 is inserted into the detection tank 11, the eluent 30 is dipped, and then the test paper 50 is obliquely placed in the receiving plane 121. When the receiving plane 121 is inclined, the bottom point of the receiving plane 121 or the extending surface of the receiving plane 121 is lower than the highest liquid level of the detection tank 11 after the eluent 30 is placed in the detection tank 11, so that the sample adding end of the detection test paper 50 can be directly inserted into the detection tank 11 after the detection test paper 50 is placed in the receiving plane 121, and the eluent 30 is dipped and the detection result is left to stand.
In the present embodiment, the receiving plane 121 is inclined from the upper surface of the operation side 10.
As shown in fig. 1 and 2, a plurality of detection grooves 11 and receiving positions 12 are provided, each detection groove 11 is independently provided, and each detection groove 11 corresponds to each receiving position 12 one to one. Because many people detect, the detection groove 11 at this moment can not communicate with each other, otherwise can not detect to everyone independently, so the condition of mixing liquid can be avoided to the independent detection groove 11 that sets up here, and to many people detect still unified detection best to avoid the eluant 30 that leads to after the batch detection to drip into different detection grooves 11. Specifically, in the present embodiment, five detection grooves 11 are provided. The multi-person detection is suitable for household self-detection of family members.
The detection platform integrally adopts a shell structure, is processed in a plastic suction mode during processing, is high in processing speed and low in cost, and can greatly save the cost especially for mass production.
When the drawing description is quoted, the new characteristics are explained; in order to avoid that repeated reference to the drawings results in an insufficiently concise description, the drawings are not referred to one by one in the case of clear description of the already described features.
The above embodiments are provided to illustrate, reproduce and deduce the technical solutions of the present invention, and to fully describe the technical solutions, the objects and the effects of the present invention, so as to make the public more thoroughly and comprehensively understand the disclosure of the present invention, and not to limit the protection scope of the present invention.
The above examples are not intended to be exhaustive of the invention and there may be many other embodiments not listed. Any replacement or modification made without departing from the spirit of the present invention shall fall within the protection scope of the present invention.

Claims (8)

1. Detection platform, its characterized in that, including operation side and support side, the operation side with there is the difference in height in the support side, the operation side is provided with detection area and storage area, detection area is provided with the detection groove of undercut, storage area is provided with sunken storage bit, detection groove with the storage bit is independent each other, the storage bit includes first holding tank and second holding tank, the second holding tank is rectangular shape, be provided with the breach on the second holding tank, the breach is in second holding tank width direction is gone up the size and is greater than second holding tank width.
2. The assay platform of claim 1, wherein the depth of the second reservoir is less than the depth of the gap.
3. The testing platform of claim 1 or 2, wherein the inner surface of the testing groove is provided with a convex part.
4. The assay platform of claim 3, wherein the protrusions are disposed on the bottom and/or side walls of the assay well.
5. The testing platform of claim 1 or 2, wherein the testing area is further provided with a receiving location, and the receiving location extends to the testing slot.
6. The testing platform of claim 5, wherein the receiving portion comprises a receiving plane, and the receiving plane is disposed at an angle of 0 to 80 degrees with respect to the upper surface of the operation side.
7. The testing platform of claim 5, wherein a plurality of testing slots are provided for each of the receiving locations, each testing slot is provided independently, and each testing slot corresponds to each receiving location.
8. A test kit comprising an elution reagent, a sampler, a test strip and the test platform of claim 1; and during packaging, the eluent, the sampler and the detection test paper are all placed on the storage bit.
CN202110759751.1A 2021-07-06 2021-07-06 Colloidal gold immunoassay platform and colloidal gold immunoassay kit Active CN113252659B (en)

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CN202110759751.1A CN113252659B (en) 2021-07-06 2021-07-06 Colloidal gold immunoassay platform and colloidal gold immunoassay kit

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Application Number Priority Date Filing Date Title
CN202110759751.1A CN113252659B (en) 2021-07-06 2021-07-06 Colloidal gold immunoassay platform and colloidal gold immunoassay kit

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CN113252659B CN113252659B (en) 2021-11-26

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CN209606170U (en) * 2018-12-27 2019-11-08 鲁联合 A kind of food safety detection equipment
CN212674939U (en) * 2020-08-28 2021-03-09 陈鹏 Portable quick detection device of blood potassium
CN112472140A (en) * 2020-05-11 2021-03-12 中山大学达安基因股份有限公司 Storage tube for sampling swab
CN212780533U (en) * 2020-06-20 2021-03-23 南京优源医疗设备有限公司 Test paper strip bracket for ACR urine analyzer

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201716224U (en) * 2010-04-16 2011-01-19 南京黎明生物制品有限公司 Swab specimen processing pipe
CN202631414U (en) * 2012-04-19 2012-12-26 泉州市蓝图生物科技有限公司 Detection box
CN204616233U (en) * 2015-05-18 2015-09-02 威海新北洋荣鑫科技股份有限公司 U shield holding tank
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CN212674939U (en) * 2020-08-28 2021-03-09 陈鹏 Portable quick detection device of blood potassium

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