CN113218733A - Tumor pathological nuclear morphological parameter determination device and determination method - Google Patents
Tumor pathological nuclear morphological parameter determination device and determination method Download PDFInfo
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- CN113218733A CN113218733A CN202110437358.0A CN202110437358A CN113218733A CN 113218733 A CN113218733 A CN 113218733A CN 202110437358 A CN202110437358 A CN 202110437358A CN 113218733 A CN113218733 A CN 113218733A
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 26
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 22
- 230000000877 morphologic effect Effects 0.000 title claims abstract description 17
- 238000000034 method Methods 0.000 title claims abstract description 10
- 238000004140 cleaning Methods 0.000 claims abstract description 47
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 39
- 230000001360 synchronised effect Effects 0.000 claims abstract description 6
- 238000004043 dyeing Methods 0.000 claims description 26
- 238000005406 washing Methods 0.000 claims description 8
- 238000005259 measurement Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 4
- 230000007170 pathology Effects 0.000 claims description 2
- 230000001613 neoplastic effect Effects 0.000 claims 1
- 238000010186 staining Methods 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 abstract description 2
- 230000010355 oscillation Effects 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
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- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to the technical field of tumor pathological detection, and discloses a tumor pathological nuclear morphological parameter determination device and a determination method, which comprise a staining cylinder assembly and a moving assembly, and are characterized in that: the outer side wall of the moving assembly is provided with an oscillating assembly, the oscillating assembly comprises a fixed hoop, a first motor, an eccentric wheel and a spring piece, the first motor is fixedly connected inside the fixed hoop, the eccentric wheel is fixedly connected with an output shaft of the first motor, and the outer surface of the eccentric wheel is mutually attached to the outer surface of the spring piece; when wasing, vibrate the subassembly and shake to removing the frame, make the hanging flower basket on the removal frame produce synchronous vibrations, make the hanging flower basket wash fast, simultaneously, the below of wasing the jar still is equipped with but reciprocating motion's motor two, when making motor two drive the blade rotation, the blade goes up and down in wasing the jar, makes the water can be stirred fast, further promotes the cleaning performance, makes the device can survey the sample fast.
Description
Technical Field
The invention relates to the technical field of tumor pathological detection, in particular to a tumor pathological nuclear morphological parameter determination device and a determination method.
Background
In pathological examination, medical staff first make pathological tissue or cell specimens into specimen pieces, then carry out a series of staining, washing, dehydrating, transparentizing and sealing on the specimen pieces, and then examine pathological slides under a microscope or by other pathological examination means. The appearance of the automatic pathological dyeing machine greatly improves the automation degree of specimen dyeing, and in order to improve the dyeing quality in the automatic dyeing process, the washing link of the automatic dyeing machine is required to be sufficient and efficient, and meanwhile, the automatic dyeing machine needs to be corrosion-resistant to a certain extent.
In the prior art, before dyeing a specimen, a hanging basket needs to be cleaned, so that the specimen is not polluted, the cleaning efficiency of the existing dyeing machine is low, the specimen needs to be cleaned in a large amount of time when being measured, and the measurement efficiency of the specimen is greatly reduced.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a tumor pathological nuclear morphological parameter measuring device and a tumor pathological nuclear morphological parameter measuring method, which have the advantage of quick cleaning, and solve the problems that the conventional dyeing machine is low in cleaning efficiency, so that a large amount of time is required for cleaning during measurement, and the measurement efficiency of a specimen is greatly reduced.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a tumour pathological nuclear morphological parameter survey device, includes dye vat subassembly and removal subassembly, its characterized in that: the outer side wall of the moving assembly is provided with an oscillating assembly, the oscillating assembly comprises a fixed hoop, a first motor, an eccentric wheel and a spring piece, the first motor is fixedly connected inside the fixed hoop, the eccentric wheel is fixedly connected with an output shaft of the first motor, and the outer surface of the eccentric wheel is mutually attached to the outer surface of the spring piece;
the inside mounting of dyeing cylinder subassembly has the washing subassembly, wash the subassembly including washing seat, motor two, cylinder and blade, the inside sliding connection who washs the seat has motor two, the bottom of motor two with the flexible end of cylinder is connected, the output shaft fixedly connected with of motor two the blade.
Preferably, the dyeing cylinder assembly comprises an outer cylinder body, a dyeing cylinder and a cleaning cylinder, and the dyeing cylinder and the cleaning cylinder are installed inside the outer cylinder body.
Preferably, the water inlet end of the cleaning cylinder is fixedly connected with a water inlet hose, and the water discharge end of the cleaning cylinder is fixedly connected with a water discharge hose.
Preferably, the washing seat is located at the bottom of the washing tub.
Preferably, the moving assembly comprises a transverse conveying frame, a vertical conveying frame, a moving frame, a mechanical arm and a hanging basket, the outer side wall of the transverse conveying frame is movably connected with the vertical conveying frame, the outer surface of the vertical conveying frame is movably connected with the moving frame, the bottom of the moving frame is fixedly connected with the mechanical arm, and the bottom of the mechanical arm is fixedly connected with the hanging basket.
Preferably, the first motor is mounted on the outer surface of the vertical conveying frame through the fixed hoop, and the spring piece is located on the outer surface of the vertical conveying frame.
Preferably, the blade is located inside the cleaning cylinder, and the bottom of the blade is connected with an output shaft of the second motor through an extension shaft.
A method for measuring tumor pathological nuclear morphological parameters comprises the following steps:
s1: before the measurement is started, the moving assembly conveys the hanging basket into the cleaning cylinder;
s2: at the moment, a water inlet hose on the cleaning cylinder conveys the water body into the cleaning cylinder;
s3: starting a second motor to enable the second motor to drive the blades to rotate, enabling the blades to stir the water body and enabling the water body to be rapidly contacted with the hanging basket, and meanwhile, starting the cylinder to enable the cylinder to drive the second motor to reciprocate, so that the water body can flow more rapidly;
s4: at the moment, a first motor is started synchronously, so that the first motor drives an eccentric wheel to continuously strike the spring piece, the spring piece drives the movable frame to vibrate, and the hanging basket on the movable frame generates synchronous vibration;
s5: the rotating water body is used for cleaning the vibrating hanging basket;
s6: after the cleaning, the tumor pathological sample sheet is placed on a hanging basket for subsequent dyeing.
(III) advantageous effects
Compared with the prior art, the invention provides a tumor pathological nuclear morphological parameter determination device and a determination method, which have the following beneficial effects:
through setting up the oscillation assembly, when wasing, the oscillation assembly shakes removal frame, makes the hanging flower basket on the removal frame produce synchronous vibrations, makes the hanging flower basket wash fast, and simultaneously, the below of wasing the jar still is equipped with but reciprocating motion's motor two, and when making two drive the blade rotation of motor, the blade goes up and down in wasing the jar, makes the water can be stirred fast, further promotes the cleaning performance, makes the device can survey the sample fast.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic structural diagram of an oscillating assembly according to the present invention;
FIG. 3 is an enlarged view of FIG. 1 taken at A.
In the figure: 10. a dye cylinder assembly; 11. an outer cylinder body; 12. a dyeing vat; 13. cleaning the cylinder; 131. a water inlet hose; 132. a drain hose; 20. a moving assembly; 21. a transverse conveying frame; 22. a vertical conveying frame; 23. a movable frame; 24. a mechanical arm; 25. a hanging basket; 30. a vibrating assembly; 31. a fixing hoop; 32. a first motor; 33. an eccentric wheel; 34. a spring plate; 40. cleaning the assembly; 41. cleaning a seat; 42. a second motor; 43. a cylinder; 44. a blade.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, an apparatus for measuring nuclear morphological parameters of tumor pathology comprises a staining cylinder assembly 10 and a moving assembly 20, wherein: the outer side wall of the moving assembly 20 is provided with an oscillating assembly 30, the oscillating assembly 30 comprises a fixed hoop 31, a first motor 32, an eccentric wheel 33 and a spring piece 34, the first motor 32 is fixedly connected inside the fixed hoop 31, an output shaft of the first motor 32 is fixedly connected with the eccentric wheel 33, and the outer surface of the eccentric wheel 33 is attached to the outer surface of the spring piece 34;
the inside of dyeing cylinder subassembly 10 is installed and is washd subassembly 40, washs subassembly 40 including wasing seat 41, the second 42 of motor, cylinder 43 and blade 44, washs the inside sliding connection of seat 41 and has the second 42 of motor, and the bottom of the second 42 of motor is connected with the flexible end of cylinder 43, and the output shaft fixedly connected with blade 44 of the second 42 of motor.
In this embodiment, specifically, the dyeing cylinder assembly 10 includes an outer cylinder 11, a dyeing cylinder 12, and a cleaning cylinder 13, and the dyeing cylinder 12 and the cleaning cylinder 13 are installed inside the outer cylinder 11.
In this embodiment, specifically, the water inlet end of the cleaning cylinder 13 is fixedly connected with a water inlet hose 131, and the water outlet end of the cleaning cylinder 13 is fixedly connected with a water outlet hose 132.
In this embodiment, the cleaning base 41 is located at the bottom of the cleaning cylinder 13.
In this embodiment, specifically, the moving assembly 20 includes a transverse conveying frame 21, a vertical conveying frame 22, a moving frame 23, a mechanical arm 24 and a hanging basket 25, the outer side wall of the transverse conveying frame 21 is movably connected with the vertical conveying frame 22, the outer surface of the vertical conveying frame 22 is movably connected with the moving frame 23, the bottom of the moving frame 23 is fixedly connected with the mechanical arm 24, and the bottom of the mechanical arm 24 is fixedly connected with the hanging basket 25.
In this embodiment, specifically, the first motor 32 is mounted on the outer surface of the vertical carriage 23 through the fixing hoop 31, and the spring plate 34 is located on the outer surface of the vertical carriage 23.
In this embodiment, specifically, the blade 44 is located inside the cleaning cylinder 13, and the bottom of the blade 44 is connected to the output shaft of the second motor 42 through an extension shaft.
A method for measuring tumor pathological nuclear morphological parameters comprises the following steps:
s1: before the measurement is started, the moving assembly conveys the hanging basket into the cleaning cylinder;
s2: at the moment, a water inlet hose on the cleaning cylinder conveys the water body into the cleaning cylinder;
s3: starting a second motor to enable the second motor to drive the blades to rotate, enabling the blades to stir the water body and enabling the water body to be rapidly contacted with the hanging basket, and meanwhile, starting the cylinder to enable the cylinder to drive the second motor to reciprocate, so that the water body can flow more rapidly;
s4: at the moment, a first motor is started synchronously, so that the first motor drives an eccentric wheel to continuously strike the spring piece, the spring piece drives the movable frame to vibrate, and the hanging basket on the movable frame generates synchronous vibration;
s5: the rotating water body is used for cleaning the vibrating hanging basket;
s6: after the cleaning, the tumor pathological sample sheet is placed on a hanging basket for subsequent dyeing.
The working principle is as follows: before the measurement is started, the basket 25 is conveyed into the cleaning cylinder 13 by the moving assembly, at the moment, the water body is conveyed into the cleaning cylinder 13 by the water inlet hose 131 on the cleaning cylinder 13, the second motor 42 is started to drive the second motor 42 to rotate, the blades 44 stir the water body to enable the water body to be rapidly contacted with the basket 25, meanwhile, the air cylinder 43 is started to drive the second motor 42 to reciprocate by the air cylinder 43, the water body flows more rapidly, at the moment, the first motor 32 is synchronously started to drive the eccentric wheel 33 to continuously hit the spring leaf 34 by the first motor 32, the spring leaf 34 drives the moving frame 23 to vibrate, the basket 25 on the moving frame 23 generates synchronous vibration, the vibrating basket 25 is cleaned by the rotating water body, and after the cleaning is finished, the tumor pathological sample piece is placed on the basket 25 to perform subsequent dyeing.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A tumor pathological nuclear morphological parameter measuring device comprises a dyeing cylinder assembly (10) and a moving assembly (20), and is characterized in that: the outer side wall of the moving assembly (20) is provided with an oscillating assembly (30), the oscillating assembly (30) comprises a fixed hoop (31), a first motor (32), an eccentric wheel (33) and a spring piece (34), the first motor (32) is fixedly connected inside the fixed hoop (31), an output shaft of the first motor (32) is fixedly connected with the eccentric wheel (33), and the outer surface of the eccentric wheel (33) is attached to the outer surface of the spring piece (34);
the internally mounted of dye vat subassembly (10) has washing subassembly (40), wash subassembly (40) including washing seat (41), second motor (42), cylinder (43) and blade (44), the inside sliding connection who washs seat (41) has second motor (42), the bottom of second motor (42) with the flexible end of cylinder (43) is connected, the output shaft fixedly connected with of second motor (42) blade (44).
2. The apparatus of claim 1, wherein the apparatus further comprises: the dyeing cylinder assembly (10) comprises an outer cylinder body (11), a dyeing cylinder (12) and a cleaning cylinder (13), wherein the dyeing cylinder (12) and the cleaning cylinder (13) are installed inside the outer cylinder body (11).
3. A tumor pathological nuclear morphological parameter determination apparatus as claimed in claim 2, further comprising: the water inlet end of the cleaning cylinder (13) is fixedly connected with a water inlet hose (131), and the water outlet end of the cleaning cylinder (13) is fixedly connected with a water outlet hose (132).
4. A tumor pathological nuclear morphological parameter determination apparatus as claimed in claim 2, further comprising: the cleaning seat (41) is positioned at the bottom of the cleaning cylinder (13).
5. The apparatus of claim 1, wherein the apparatus further comprises: remove subassembly (20) including horizontal transport frame (21), vertical transport frame (22), remove frame (23), arm (24) and hanging flower basket (25), the lateral wall swing joint of horizontal transport frame (21) has vertical transport frame (22), the surface swing joint of vertical transport frame (22) has remove frame (23), the bottom fixedly connected with that removes frame (23) arm (24), the bottom fixedly connected with of arm (24) hanging flower basket (25).
6. A tumor pathological nuclear morphological parameter determination apparatus as claimed in claim 5, further comprising: the first motor (32) is mounted on the outer surface of the vertical conveying frame (23) through the fixing hoop (31), and the spring piece (34) is located on the outer surface of the vertical conveying frame (23).
7. A tumor pathological nuclear morphological parameter determination apparatus as claimed in claim 2, further comprising: the blade (44) is positioned inside the cleaning cylinder (13), and the bottom of the blade (44) is connected with an output shaft of the second motor (42) through an extension shaft.
8. A method for measuring nuclear morphological parameters of neoplastic pathology according to any one of claims 1 to 7, comprising the steps of:
s1: before the measurement is started, the moving assembly conveys the hanging basket into the cleaning cylinder;
s2: at the moment, a water inlet hose on the cleaning cylinder conveys the water body into the cleaning cylinder;
s3: starting a second motor to enable the second motor to drive the blades to rotate, enabling the blades to stir the water body and enabling the water body to be rapidly contacted with the hanging basket, and meanwhile, starting the cylinder to enable the cylinder to drive the second motor to reciprocate, so that the water body can flow more rapidly;
s4: at the moment, a first motor is started synchronously, so that the first motor drives an eccentric wheel to continuously strike the spring piece, the spring piece drives the movable frame to vibrate, and the hanging basket on the movable frame generates synchronous vibration;
s5: the rotating water body is used for cleaning the vibrating hanging basket;
s6: after the cleaning, the tumor pathological sample sheet is placed on a hanging basket for subsequent dyeing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110437358.0A CN113218733A (en) | 2021-04-22 | 2021-04-22 | Tumor pathological nuclear morphological parameter determination device and determination method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110437358.0A CN113218733A (en) | 2021-04-22 | 2021-04-22 | Tumor pathological nuclear morphological parameter determination device and determination method |
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| CN113218733A true CN113218733A (en) | 2021-08-06 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202013296U (en) * | 2011-01-14 | 2011-10-19 | 孝感泰康达医疗设备有限公司 | Biological tissue dyer |
| CN202984160U (en) * | 2012-12-13 | 2013-06-12 | 麦克奥迪（厦门）医疗诊断系统有限公司 | Flushing device of automatic pathology staining machine |
| CN107157422A (en) * | 2017-07-22 | 2017-09-15 | 佛山市正略信息科技有限公司 | A kind of lift type water tank with cleaning function draws basket |
| CN206661805U (en) * | 2017-03-05 | 2017-11-24 | 李冰 | A kind of fine arts paintbrush cleaning device |
| CN212321231U (en) * | 2019-12-25 | 2021-01-08 | 天津迪安医学检验实验室有限公司 | Biological tissue dyeing machine |
| CN212418612U (en) * | 2020-03-26 | 2021-01-29 | 倍养健康科技（上海）有限公司 | Cleaning system for powdery material |
-
2021
- 2021-04-22 CN CN202110437358.0A patent/CN113218733A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202013296U (en) * | 2011-01-14 | 2011-10-19 | 孝感泰康达医疗设备有限公司 | Biological tissue dyer |
| CN202984160U (en) * | 2012-12-13 | 2013-06-12 | 麦克奥迪（厦门）医疗诊断系统有限公司 | Flushing device of automatic pathology staining machine |
| CN206661805U (en) * | 2017-03-05 | 2017-11-24 | 李冰 | A kind of fine arts paintbrush cleaning device |
| CN107157422A (en) * | 2017-07-22 | 2017-09-15 | 佛山市正略信息科技有限公司 | A kind of lift type water tank with cleaning function draws basket |
| CN212321231U (en) * | 2019-12-25 | 2021-01-08 | 天津迪安医学检验实验室有限公司 | Biological tissue dyeing machine |
| CN212418612U (en) * | 2020-03-26 | 2021-01-29 | 倍养健康科技（上海）有限公司 | Cleaning system for powdery material |
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Application publication date: 20210806 |
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