CN113208948A - 一种保湿洁面乳及其制备方法 - Google Patents
一种保湿洁面乳及其制备方法 Download PDFInfo
- Publication number
- CN113208948A CN113208948A CN202110431399.9A CN202110431399A CN113208948A CN 113208948 A CN113208948 A CN 113208948A CN 202110431399 A CN202110431399 A CN 202110431399A CN 113208948 A CN113208948 A CN 113208948A
- Authority
- CN
- China
- Prior art keywords
- facial cleanser
- essence
- skin
- sodium
- moisturizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000001815 facial effect Effects 0.000 title claims abstract description 41
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title abstract description 5
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 11
- 239000003906 humectant Substances 0.000 claims abstract description 9
- 239000004094 surface-active agent Substances 0.000 claims abstract description 9
- 239000002562 thickening agent Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 11
- 239000011259 mixed solution Substances 0.000 claims description 11
- 239000003755 preservative agent Substances 0.000 claims description 9
- 230000002335 preservative effect Effects 0.000 claims description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 239000003792 electrolyte Substances 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 5
- 108010035532 Collagen Proteins 0.000 claims description 5
- ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 claims description 5
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 5
- 229940044176 ceramide 3 Drugs 0.000 claims description 5
- 229920001436 collagen Polymers 0.000 claims description 5
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 5
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 5
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 5
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 4
- JDRSMPFHFNXQRB-CMTNHCDUSA-N Decyl beta-D-threo-hexopyranoside Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 claims description 4
- 102000016942 Elastin Human genes 0.000 claims description 4
- 108010014258 Elastin Proteins 0.000 claims description 4
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 claims description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
- 229920002125 Sokalan® Polymers 0.000 claims description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 4
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 4
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 4
- 229940073499 decyl glucoside Drugs 0.000 claims description 4
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 claims description 4
- 229920002549 elastin Polymers 0.000 claims description 4
- 229960005323 phenoxyethanol Drugs 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 229940057950 sodium laureth sulfate Drugs 0.000 claims description 4
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 claims description 4
- 235000010254 Jasminum officinale Nutrition 0.000 claims description 3
- 240000005385 Jasminum sambac Species 0.000 claims description 3
- 241000220317 Rosa Species 0.000 claims description 3
- 230000002421 anti-septic effect Effects 0.000 claims description 3
- 229960005150 glycerol Drugs 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims description 2
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- 239000004475 Arginine Substances 0.000 claims description 2
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 claims description 2
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- 235000006029 Prunus persica var nucipersica Nutrition 0.000 claims description 2
- 244000017714 Prunus persica var. nucipersica Species 0.000 claims description 2
- 241000508269 Psidium Species 0.000 claims description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 2
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims description 2
- YKDMBTQVKVEMSA-UHFFFAOYSA-N diethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCCOC(=O)CCCCCCCCCCCCCCCCC YKDMBTQVKVEMSA-UHFFFAOYSA-N 0.000 claims description 2
- 229940111071 diethylene glycol distearate Drugs 0.000 claims description 2
- 229940051250 hexylene glycol Drugs 0.000 claims description 2
- 239000001103 potassium chloride Substances 0.000 claims description 2
- 235000011164 potassium chloride Nutrition 0.000 claims description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 2
- 229960003415 propylparaben Drugs 0.000 claims description 2
- 108700004121 sarkosyl Proteins 0.000 claims description 2
- 235000002639 sodium chloride Nutrition 0.000 claims description 2
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 2
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 2
- 235000011152 sodium sulphate Nutrition 0.000 claims description 2
- 244000061520 Angelica archangelica Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 claims 1
- 238000004140 cleaning Methods 0.000 abstract description 8
- 239000002537 cosmetic Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 239000006260 foam Substances 0.000 abstract description 4
- 239000004519 grease Substances 0.000 abstract description 4
- 230000004888 barrier function Effects 0.000 abstract description 3
- 238000005238 degreasing Methods 0.000 abstract description 3
- 239000002085 irritant Substances 0.000 abstract description 3
- 231100000021 irritant Toxicity 0.000 abstract description 3
- 239000000686 essence Substances 0.000 description 16
- 230000000052 comparative effect Effects 0.000 description 10
- 235000011187 glycerol Nutrition 0.000 description 3
- 230000037307 sensitive skin Effects 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000004584 polyacrylic acid Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 244000144730 Amygdalus persica Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 240000002045 Guettarda speciosa Species 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 206010050637 Skin tightness Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 229960002668 sodium chloride Drugs 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
本发明属于化妆品领域，公开了一种保湿洁面乳及其制备方法。该保湿洁面乳，包含以下按质量百分比计的组分：表面活性剂25％～45％、保湿剂1％～10％、增稠剂1％～5％、珠光剂1％～5％。本发明提供的保湿洁面乳温和亲肤、安全无刺激、不增加皮肤负担，泡沫丰富、去油脂和污垢的效果好，能够深层清洁肌肤，使皮肤干净舒爽，亲和肌肤；并且在去除油脂和污垢的同时，可以在皮肤表面形成天然保湿屏障，防止水分流失，起到保湿、增加皮肤弹性、提升皮肤紧致度，提高防止皮肤干燥紧绷起皮的效果。
Description
技术领域
本发明属于化妆品领域，具体涉及一种保湿洁面乳及其制备方法。
背景技术
随着人们生活节奏的加快、城市空气污染的加重，裸露在外部的脸经常是油光满面。而且彩妆类产品也越来越普及，作为化妆品的重要一个分支，其在现代人们生活中占据着重要的地位，清洁对于肌肤保养来说，是至关重要的第一步。干净的肌肤才能吸收接下来的精华、乳液、面霜等各项护理，滋润每一个细胞。尤其是在夏天，肌肤承受着高温以及强烈日晒的摧残，隔离、防晒、粉底、彩妆甚至大气中的灰尘及细菌等也在加重着肌肤压力，清洁肌肤尤为重要。如果连肌肤表层的油脂和污垢都没有洗干净，滞留的油脂和污垢不但损害肌肤，还会形成一个闭合的屏障，影响后续护肤品中养分的渗透和吸收。洁面，是采用洗涤的方式除去面部皮肤表面附着的皮脂、角质层屑片、汗液等皮肤生理代谢产物以及灰尘、微生物、化妆品残留物等，是护肤的第一步，而错误地选择洁面产品是导致很多人出现皮肤问题的根源。现有技术中皂基类的洁面产品具有很强的清洁效果，但因清洁力较强，脱脂性较高，使用后容易出现皮肤紧绷，干燥等不适感，容易造成敏感肌肤发生不良反应，也不适合低温、干燥等条件下使用。因此，研发一种保湿洁面乳尤为重要。
发明内容
本发明第一方面的目的，在于提供一种保湿洁面乳。
本发明第二方面的目的，在于提供第一方面的保湿洁面乳的制备方法。
为了实现上述目的，本发明所采取的技术方案是：
本发明的第一个方面，提供一种保湿洁面乳，包含以下按质量百分比计的组分：表面活性剂25％～45％、保湿剂1％～10％、增稠剂1％～5％、珠光剂1％～5％。
优选地，所述保湿洁面乳包含以下按质量百分比计的组分：表面活性剂27％～37％、保湿剂4.011％～8％、增稠剂2.5％～4％、珠光剂2％～4％。
优选地，所述保湿洁面乳还包含：pH调节剂、电解质、防腐剂和香精。
优选地，所述pH调节剂的含量按质量百分比计为0.1％～1％；进一步为0.25％～0.5％。
优选地，所述电解质的含量按质量百分比计为0.1％～1％；进一步为0.3％～0.8％。
优选地，所述防腐剂、香精的含量为适量，符合国家、行业等相关规定。
优选地，所述防腐剂的含量按质量百分比计为0.1％～1.2％；进一步为0.15％～1％。
优选地，所述香精的含量按质量百分比计为0.01％～0.2％；进一步为0.0275％～0.15％。
优选地，所述保湿洁面乳还包含水；所述水的用量为余量。
优选地，所述表面活性剂为月桂基硫酸钠、月桂酰肌氨酸钠、月桂醇聚醚硫酸酯钠、椰油酰胺DEA、椰油酰胺丙基甜菜碱和癸基葡糖苷中的至少一种；进一步为月桂醇聚醚硫酸酯钠、椰油酰胺DEA、椰油酰胺丙基甜菜碱和癸基葡糖苷中的至少一种。
优选地，所述保湿剂为丙二醇、丁二醇、己二醇、透明质酸钠、甘油、神经酰胺3、水解胶原和水解弹性蛋白中的至少一种；进一步为透明质酸钠、甘油、神经酰胺3、水解胶原和水解弹性蛋白中的至少一种。
优选地，所述增稠剂为丙烯酸聚合物；进一步为聚丙烯酸、聚丙烯酸钠、聚丙烯酸酯交联聚合物和丙烯酸(酯)聚醚中的至少一种。
优选地，所述珠光剂为乙二醇单硬脂酸酯、二乙二醇单硬脂酸酯、二乙二醇双硬脂酸酯和乙二醇二硬脂酸酯中的至少一种；进一步为乙二醇二硬脂酸酯。
优选地，所述pH调节剂为氢氧化钠、氢氧化钾、三乙醇胺、氨甲基丙醇和精氨酸中的至少一种；进一步为三乙醇胺。
优选地，所述电解质为氯化钾、硫酸钠和氯化钠中的至少一种；进一步为氯化钠。
优选地，所述防腐剂为苯氧乙醇、辛酰羟肟酸、羟苯丙酯、羟苯丁酯、羟苯甲酯和甲基氯异噻唑啉酮中的至少一种；更优选为苯氧乙醇和羟苯甲酯中的至少一种。
优选地，所述香精为玫瑰香精、当归香精、茉莉香精、蜜桃香精和番石榴香精中的至少一种；进一步为玫瑰香精、茉莉香精和蜜桃香精中的至少一种。
本发明的第二方面，提供第一方面的保湿洁面乳的制备方法，步骤如下：
(1)取表面活性剂、部分防腐剂、珠光剂、增稠剂、部分保湿剂和水混合，得到混合液A；
(2)将pH调节剂和混合液A混合，得到混合液B；
(3)将混合液B、剩余保湿剂、剩余防腐剂、电解质和香精混合，得到保湿洁面乳。
优选地，步骤(1)中所述混合液A的温度为70～90℃。
优选地，步骤(2)中所述混合液A的温度为50～70℃。
优选地，步骤(3)中所述混合液B的温度为40～50℃。
本发明的有益效果是：
本发明提供的保湿洁面乳温和亲肤、安全无刺激、不增加皮肤负担，泡沫丰富、去油脂和污垢的效果好，能够深层清洁肌肤，使皮肤干净舒爽，亲和肌肤；并且在去除油脂和污垢的同时，可以在皮肤表面形成天然保湿屏障，防止水分流失，起到保湿、增加皮肤弹性、提升皮肤紧致度，提高防止皮肤干燥紧绷起皮的效果。
本发明提供的保湿洁面乳的生产工艺简单，可进行大规模生产，具有广阔的市场前景。
具体实施方式
以下通过具体的实施例对本发明的内容作进一步详细的说明。
本实施例中所采用的原料，除特殊说明外，均通过常规手段制备或者通过商业渠道购买。
实施例及对比例
实施例1～4及对比例1～3的保湿洁面乳的配方如表1所示。
实施例1～4的保湿洁面乳的制备方法如下：
取月桂醇聚醚硫酸酯钠、椰油酰胺DEA、椰油酰胺丙基甜菜碱、癸基葡糖苷、羟苯甲酯、乙二醇二硬脂酸酯、甘油、聚丙烯酸(购于路博润，SF-1)、水混合，加热至80℃，边搅拌边降温至60℃；加入三乙醇胺，继续降温至45℃；加入水解胶原(购于台湾昱智HP)、水解弹性蛋白(购于亚什兰)、透明质酸钠(购于华熙福瑞达)、神经酰胺3、氯化钠、苯氧乙醇、香精，搅拌均匀即可。
对比例1的保湿洁面乳的制备方法与实施例1的保湿洁面乳的制备方法一致，区别仅在于不添加水解胶原。
对比例2的保湿洁面乳的制备方法与实施例1的保湿洁面乳的制备方法一致，区别仅在于不添加透明质酸钠。
对比例3的保湿洁面乳的制备方法与实施例1的保湿洁面乳的制备方法一致，区别仅在于不添加神经酰胺3。
表1实施例1～4和对比例1～3的保湿洁面乳的配方
效果实施例
选择40名敏感肌肤志愿者，在耳后进行过敏试验，实施例1～4的保湿洁面乳均无过敏现象。
选择70名敏感肌肤志愿者，将志愿者分成7组，分别取等量实施例1～4和对比例1～3的保湿洁面乳挤于手中，加水揉搓起泡，然后清洁面部，按摩2min，用清水洗净残留的泡沫，分别使用4周。使用前和4周后，对志愿者的面部皮肤进行观察、评分并进行访问，结果如表2所示：本申请提供的保湿洁面乳的评分高于对比例：使用1～4的保湿洁面乳后感觉清爽滋润，无刺激性疼痛感，对面部皮肤进行观察，洗后不干燥，皮肤细嫩；使用对比例1～3的保湿洁面乳后感觉清爽无刺激无疼痛感，对面部皮肤进行观察，洗后略显紧绷。
表2实施例1～4和对比例1～3的保湿洁面乳的评分
上述实施例为本发明较佳的实施方式，但本发明的实施方式并不受上述实施例的限制，其他的任何未背离本发明的精神实质与原理下所作的改变、修饰、替代、组合、简化，均应为等效的置换方式，都包含在本发明的保护范围之内。
Claims (10)
1.一种洁面乳，包含以下按质量百分比计的组分：表面活性剂25％～45％、保湿剂1％～10％、增稠剂1％～5％、珠光剂1％～5％。
2.根据权利要求1所述的洁面乳，其特征在于：所述洁面乳包含以下按质量百分比计的组分：表面活性剂27％～37％、保湿剂4.011％～8％、增稠剂2.5％～4％、珠光剂2％～4％。
3.根据权利要求1所述的洁面乳，其特征在于：所述表面活性剂为月桂基硫酸钠、月桂酰肌氨酸钠、月桂醇聚醚硫酸酯钠、椰油酰胺DEA、椰油酰胺丙基甜菜碱和癸基葡糖苷中的至少一种。
4.根据权利要求1所述的洁面乳，其特征在于：所述保湿剂为丙二醇、丁二醇、己二醇、透明质酸钠、甘油、神经酰胺3、水解胶原和水解弹性蛋白中的至少一种。
5.根据权利要求1所述的洁面乳，其特征在于：所述增稠剂为丙烯酸聚合物。
6.根据权利要求1所述的洁面乳，其特征在于：所述珠光剂为乙二醇单硬脂酸酯、二乙二醇单硬脂酸酯、二乙二醇双硬脂酸酯和乙二醇二硬脂酸酯中的至少一种。
7.根据权利要求1～6中任一项所述的洁面乳，其特征在于：所述洁面乳还包含：pH调节剂、电解质、防腐剂和香精。
8.根据权利要求7所述的洁面乳，其特征在于：
所述pH调节剂为氢氧化钠、氢氧化钾、三乙醇胺、氨甲基丙醇和精氨酸中的至少一种；
所述电解质为氯化钾、硫酸钠和氯化钠中的至少一种；
所述防腐剂为苯氧乙醇、辛酰羟肟酸、羟苯丙酯、羟苯丁酯、羟苯甲酯和甲基氯异噻唑啉酮中的至少一种；
所述香精为玫瑰香精、当归香精、茉莉香精、蜜桃香精和番石榴香精中的至少一种。
9.根据权利要求8所述的洁面乳，其特征在于：
所述pH调节剂的含量按质量百分比计为0.1％～1％；
所述电解质的含量按质量百分比计为0.1％～1％；
所述防腐剂的含量按质量百分比计为0.1％～1.2％；
所述香精的含量按质量百分比计为0.01％～0.2％。
10.权利要求8或9所述的洁面乳的制备方法，其特征在于，包括如下步骤：
(1)将表面活性剂、部分防腐剂、珠光剂、增稠剂、部分保湿剂和水混合，得到混合液A；
(2)将pH调节剂和混合液A混合，得到混合液B；
(3)将混合液B、剩余保湿剂、剩余防腐剂、电解质和香精混合，得到洁面乳。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110431399.9A CN113208948A (zh) | 2021-04-21 | 2021-04-21 | 一种保湿洁面乳及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110431399.9A CN113208948A (zh) | 2021-04-21 | 2021-04-21 | 一种保湿洁面乳及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113208948A true CN113208948A (zh) | 2021-08-06 |
Family
ID=77088200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110431399.9A Pending CN113208948A (zh) | 2021-04-21 | 2021-04-21 | 一种保湿洁面乳及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113208948A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796063A (zh) * | 2022-06-02 | 2022-07-29 | 广州一一生物技术有限公司 | 一种温和抑菌的洁面乳及其应用 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105476950A (zh) * | 2014-12-22 | 2016-04-13 | 吉林伊捷思化学有限公司 | 无添加天然保湿泡沫洁面乳 |
| CN106726698A (zh) * | 2016-11-21 | 2017-05-31 | 上海相宜本草化妆品股份有限公司 | 一种氨基酸型洁面乳及其制备方法 |
| WO2018040415A1 (zh) * | 2016-08-27 | 2018-03-08 | 朱耀灯 | 一种深层补水保湿洁面乳 |
| CN109700678A (zh) * | 2018-12-24 | 2019-05-03 | 深圳市琉璃光生物科技有限公司 | 一种保湿修护洁面乳及其制备方法 |
| CN111000768A (zh) * | 2019-12-19 | 2020-04-14 | 天津达仁堂京万红药业有限公司 | 一种植萃舒缓氨基酸洁面乳及其制备方法 |
| CN111419767A (zh) * | 2020-04-17 | 2020-07-17 | 安婕妤化妆品科技股份有限公司 | 一种保湿、抗炎、抗衰老的精华液及其制备方法 |
-
2021
- 2021-04-21 CN CN202110431399.9A patent/CN113208948A/zh active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105476950A (zh) * | 2014-12-22 | 2016-04-13 | 吉林伊捷思化学有限公司 | 无添加天然保湿泡沫洁面乳 |
| WO2018040415A1 (zh) * | 2016-08-27 | 2018-03-08 | 朱耀灯 | 一种深层补水保湿洁面乳 |
| CN106726698A (zh) * | 2016-11-21 | 2017-05-31 | 上海相宜本草化妆品股份有限公司 | 一种氨基酸型洁面乳及其制备方法 |
| CN109700678A (zh) * | 2018-12-24 | 2019-05-03 | 深圳市琉璃光生物科技有限公司 | 一种保湿修护洁面乳及其制备方法 |
| CN111000768A (zh) * | 2019-12-19 | 2020-04-14 | 天津达仁堂京万红药业有限公司 | 一种植萃舒缓氨基酸洁面乳及其制备方法 |
| CN111419767A (zh) * | 2020-04-17 | 2020-07-17 | 安婕妤化妆品科技股份有限公司 | 一种保湿、抗炎、抗衰老的精华液及其制备方法 |
Non-Patent Citations (4)
| Title |
|---|
| （日）一之介著；谢丽敏译: "《护肤图鉴》", 31 July 2020, 青岛出版社 * |
| 冯年平等: "《中药经皮给药与功效性化妆品》", 31 May 2019, 中国医药科技出版社 * |
| 无: "松竹集萃水凝补水洗面奶", 《国产非特殊用途化妆品备案服务平台，HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20150811083005KITSS&NID=20150811083005KITSS》 * |
| 王普兵: "洁面产品配方开发技巧", 《广东化工》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796063A (zh) * | 2022-06-02 | 2022-07-29 | 广州一一生物技术有限公司 | 一种温和抑菌的洁面乳及其应用 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109528523B (zh) | 一种氨基酸洁面乳 | |
| CN111643433A (zh) | 一种控油去屑洗发组合物 | |
| CN107496317B (zh) | 一种含美洲大蠊活性成分的修复护理洗发露 | |
| CN110897937A (zh) | 一种泡泡沐浴油及其制备方法 | |
| CN105769605A (zh) | 含人体活性透明质酸或人体活性透明质酸盐的化妆品 | |
| CN104666235A (zh) | 一种卸妆洁面补水排浊露及其制备方法 | |
| CN112675048A (zh) | 一种双层卸妆慕斯及其制备方法 | |
| CN111184642A (zh) | 一种二合一洗发沐浴组合物 | |
| CN108403609B (zh) | 一种紧致润肤洁面啫喱 | |
| CN113208948A (zh) | 一种保湿洁面乳及其制备方法 | |
| CN114306174A (zh) | 一种温和保湿的玫瑰面部磨砂膏及其制备方法 | |
| CN104161709A (zh) | 一种叶绿素洁颜乳 | |
| CN107929106A (zh) | 一种天然椰子油洁面乳及其制备方法 | |
| CN114848525B (zh) | 一种婴幼儿温和清洁组合物及其应用 | |
| CN110448520A (zh) | 一种洗发水及其制备方法 | |
| CN105078818A (zh) | 一种洁面后使用的按摩调理水及其制备方法 | |
| CN114681338A (zh) | 一种沐浴慕斯气雾剂及其制备方法 | |
| CN112336662B (zh) | 一种舒缓沐浴露及其制备方法和应用 | |
| CN110742819B (zh) | 一种氨基酸洁颜蜜 | |
| CN113081889A (zh) | 一种三阶段洗护合一组合物 | |
| CN112294674A (zh) | 一种纯植物深层清洁氨基酸洁面慕斯 | |
| CN112569167A (zh) | 一种基于氨基酸抗敏成分的洗护产品及其制备工艺 | |
| CN111494275A (zh) | 一种适合婴幼儿的眼部无刺激的洗涤用品及其制备方法 | |
| CN111437215A (zh) | 一种壳聚糖凝胶的制备及在预防脱发洗发水中的应用 | |
| CN111714393A (zh) | 一种皮肤活化组合物及其活化乳液 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210806 |
|
| RJ01 | Rejection of invention patent application after publication |