CN113198587A

CN113198587A - High-purity multi-material mixed pharmaceutical equipment with controllable proportion

Info

Publication number: CN113198587A
Application number: CN202110507175.1A
Authority: CN
Inventors: 高晓静
Original assignee: Individual
Current assignee: Shandong Xinyi Pharmaceutical Co ltd
Priority date: 2021-05-10
Filing date: 2021-05-10
Publication date: 2021-08-03
Anticipated expiration: 2041-05-10
Also published as: CN113198587B

Abstract

The invention discloses high-purity multi-material mixed pharmaceutical equipment with controllable proportion, which comprises: the inner wall of the upper end of the supporting shell is fixedly connected with a grinding box; the middle part of the tablet grinding disc is fixedly connected with a rotating rod; the extrusion conveying box is penetrated through the right lower side and the front lower side of the supporting shell; the lower end of the sealing device is connected with an electric telescopic rod in an installing manner; the powder conveying plate is fixedly connected with a rotating disc at the lower end of the powder conveying plate. This many materials of high purity of steerable proportion mix pharmaceutical equipment, the convenience is added according to the proportion to multiple raw materials, avoids appearing the phenomenon that the ratio is out of control, influences the quality of medicine to and the convenience carries out abundant grinding to the raw materials, improves the fineness of tablet powder, makes things convenient for later stage processing to use, also conveniently carries out the intensive mixing to multiple raw materials simultaneously, also makes things convenient for the regulation control to extrude the shape size of tablet simultaneously.

Description

High-purity multi-material mixed pharmaceutical equipment with controllable proportion

Technical Field

The invention relates to the related technical field of pharmaceutical equipment, in particular to high-purity multi-material mixed pharmaceutical equipment with controllable proportion.

Background

In pharmaceutical engineering, when tablets are manufactured, tablet powder needs to be fully mixed firstly, then tablet manufacturing is carried out by adopting a tablet press, and various tablet powder mixing devices are available on the market, and are divided into a V-shaped mixer, a two-position mixer, a three-dimensional mixer and a double-cone mixer according to a mixing motion mode, and the mixing devices have different characteristics and purposes.

With reference to the authorization notice number CN108654477B, a three-dimensional motion mixer for pharmacy can drive a mixing barrel to rotate in six directions, namely up, down, front, rear, left and right directions, through the joint operation of a driving motor and a rotating motor, so as to increase the rotating angle and rotating force of the mixing barrel, so that the mixing speed of materials is faster and the efficiency is higher;

however, the pharmaceutical device has the following problems in the use process, mainly including:

1. various raw materials are inconvenient to add according to a proportion, the phenomenon of out-of-control proportion is easy to occur, the quality of the medicine is influenced, and stable feeding and adding of the tablet raw materials are inconvenient, so that the use is influenced;

2. the raw materials are not convenient to be fully ground, the fineness of the tablet powder is influenced, the tablet powder is not convenient to be processed and used later, and the rapid and full grinding treatment of the tablet is not convenient;

3. inconvenient carry out intensive mixing to multiple tablet raw materials, also inconvenient regulation control extrudes the shape size of tablet simultaneously, and the unloading route that the tablet mixes the powder is adjusted to inconvenient as required, influences work efficiency, for this we have provided the high-purity of a steerable proportion and have expected mixed pharmaceutical equipment more, is used for solving above-mentioned problem.

Disclosure of Invention

The invention aims to provide high-purity multi-material mixing pharmaceutical equipment with controllable proportion, and aims to solve the problems that the existing pharmaceutical device provided in the background technology is inconvenient for adding various raw materials according to proportion, is easy to cause the phenomenon of out-of-control proportion, influences the quality of medicines, is inconvenient for stably feeding and adding tablet raw materials, influences the use, is inconvenient for fully grinding the raw materials, influences the fineness of tablet powder, is inconvenient for later processing and use, is inconvenient for quickly and fully grinding tablets, is inconvenient for fully mixing various tablet raw materials, is inconvenient for regulating and controlling the shape and size of the extruded tablets, is inconvenient for regulating the blanking path of the tablet mixed powder according to needs, and influences the working efficiency.

In order to achieve the purpose, the invention provides the following technical scheme: a ratio-controllable high purity multi-material mixing pharmaceutical plant comprising:

the grinding device comprises a supporting shell, a grinding box is fixedly connected to the inner wall of the upper end of the supporting shell, a rotating shaft is connected to the outer wall of the lower end of the grinding box in a sliding mode, and a weighing balance is installed and connected to a spiral conveying rod arranged at the upper end of the grinding box;

the middle part of the tablet grinding disc is fixedly connected with a rotating rod, and the upper end of the rotating rod penetrates through the grinding box and is fixedly connected with the output end of the first motor;

the extrusion conveying box penetrates through the right lower side and the front lower side of the supporting shell, a spiral conveying rod is rotatably connected inside the extrusion conveying box, and one end, located inside the supporting shell, of the spiral conveying rod is fixedly connected with the output end of the third motor through a bolt;

the lower end of the sealing device is connected with an electric telescopic rod in an installing mode, and the electric telescopic rod is connected to the inner wall of the upper end of the limiting blanking groove in an installing mode;

the lower extreme fixedly connected with rolling disc of powder conveying board, and the left side meshing of rolling disc is connected with the adjusting disk, simultaneously the axis of adjusting disk passes through the output fixed connection of bolt and fourth motor.

As a preferred technical solution of the present invention, the diameter of the inner wall of the support housing is larger than the diameter of the outer wall of the mixing box, and the diameter of the inner wall of the mixing box is larger than the diameter of the outer wall of the grinding box;

wherein, the upper and lower both ends surface of mixing box all is serration structure, and the connected mode of mixing box and adjusting gear is connected for the meshing to the adjusting gear on right side passes through the output fixed connection of connecting axle and second motor, simultaneously the mixing box constitutes revolution mechanic in support shell's inside.

Through adopting above-mentioned technical scheme, because the connected mode of mixing box and adjusting gear is connected for the meshing, conveniently drive the mixing box and carry out stable rotation, improve mixing efficiency, facilitate the use.

In a preferred embodiment of the present invention, the rotating shaft and the rotating rod are both in an L-shaped structure, the tablet-grinding disk forms a swing structure inside the grinding box via the rotating rod, and the lower end of the rotating shaft is fixedly connected with the stirring blade, and the stirring blade forms a rotating structure inside the mixing box.

Through adopting above-mentioned technical scheme, because axis of rotation and rotary rod all are "L" style of calligraphy structure, conveniently drive the tablet abrasive disc and carry out the oscillating rotation, convenient abundant even abrasive treatment makes things convenient for the tablet abrasive disc to carry out abundant contact with the bottom face that grinds the case to be convenient for abundant quick abrasive treatment, facilitate the use.

As a preferred technical scheme of the invention, the upper ends of the single bodies of the rotating shafts are fixedly connected with rotating gears, the single bodies of the rotating gears are distributed in a diamond shape, the single bodies of the rotating gears are meshed with the toothed belt, and the single bodies of the rotating gears and the driven gears form a linkage structure through connecting gears.

Through adopting above-mentioned technical scheme, because be the rhombus between the monomer of rolling gear and distribute, conveniently drive the monomer of axis of rotation and carry out rotation when stable, convenient abundant stirring mixes tablet powder, improves the work efficiency of the tablet powder that the stirring was mixed, facilitates the use.

As a preferred technical scheme, the single bodies of the extrusion conveying box are vertically arranged, an extrusion molding port is formed in one end, located on the outer side of the supporting shell, of the extrusion conveying box, and the size of the opening of the single body on the right side of the extrusion molding port is larger than that of the opening of the single body at the front end of the extrusion molding port;

wherein, the feed inlet that the extrusion moulding mouth is located support housing's inside is the one-to-one setting with the discharge gate on the regulating box, and the upper end of regulating box is through spacing silo fixed connection on support housing's inner wall, simultaneously the lower extreme of spacing silo down is hopper-shaped structure.

Through adopting above-mentioned technical scheme, because the discharge gate that the extrusion moulding mouth is located the feed inlet of support housing's inside and on the regulating box is the one-to-one setting, conveniently to mixing good tablet powder unloading to the conveying case that extrudes that corresponds in, conveniently extrude corresponding tablet.

As a preferable technical scheme, the inner part of the adjusting box is rotatably connected with a medicine powder conveying plate in a fan-shaped structure, the upper surface of the medicine powder conveying plate is arranged in an inclined mode, meanwhile, two sides of the medicine powder conveying plate are fixedly connected with anti-leakage baffles, and the height size of each anti-leakage baffle is smaller than the depth size of the adjusting box.

Through adopting above-mentioned technical scheme, because the inside of regulating box rotates and is connected with the powder conveying board that is fan-shaped structure, and the upper surface of powder conveying board is the slope setting, makes things convenient for the tablet powder that holds on the powder conveying board to carry out spacing the depositing through the leak protection baffle, avoids unrestrained, the quick unloading of also being convenient for simultaneously facilitates the use.

As a preferred technical scheme of the invention, the medicine powder conveying plate forms a rotating structure in the adjusting box through the rotating disc and the adjusting disc, and the rotating angle of the medicine powder conveying plate is 0-90 degrees.

By adopting the technical scheme, because the rotation angle of the powder conveying plate is 0-90 degrees, the powder conveying plate can be conveniently rotated intermittently, so that the accurate opening of the corresponding adjusting box is convenient, the tablet powder can be conveniently fed into the extrusion conveying box, the required tablets with different sizes can be conveniently produced, and the tablet conveying device is convenient to use.

As the preferred technical scheme of the invention, the sealing device comprises a supporting plate, a leakage-proof fixture block and a fixed limiting shell, wherein the upper end surface of the supporting plate is fixedly connected with the leakage-proof fixture block, the leakage-proof fixture block is in sliding connection with the fixed limiting shell, and the lower end surface of the fixed limiting shell is fixedly provided with an electric telescopic rod;

wherein, the backup pad is fretwork column structure, and the leak protection fixture block of erection joint is the block with the lower extreme opening part of mixing box in the backup pad and is connected.

Through adopting above-mentioned technical scheme, because be sliding connection between leak protection fixture block and the fixed spacing shell, make things convenient for the lower extreme opening of leak protection fixture block and mixing box to carry out stable block, avoid influencing the use, the unloading of also being convenient for simultaneously is handled, and convenient control unloading facilitates the use.

As a preferred technical scheme, a horizontal central axis of the weighing balance is parallel to a horizontal central axis of the grinding box, the lower surface of the grinding box is of a hollow structure, and meshes of the lower surface of the grinding box are uniformly arranged.

Through adopting above-mentioned technical scheme, because the horizontal axis of weighing the balance parallels with the horizontal axis of grinding the case, conveniently carry out accurate weighing to multiple tablet raw materials, conveniently control accurate ratio, avoid the tablet ratio inaccurate, influence the quality of tablet, influence the use.

Compared with the prior art, the invention has the beneficial effects that: the high-purity multi-material mixing pharmaceutical equipment with the controllable proportion has the advantages that multiple raw materials can be conveniently added according to the proportion, the phenomenon that the proportion is out of control is avoided, the quality of medicines is influenced, the raw materials are conveniently and fully ground, the fineness of tablet powder is improved, the later-stage processing and use are facilitated, meanwhile, the multiple raw materials are conveniently and fully mixed, and meanwhile, the shape and the size of the extruded tablets are conveniently adjusted and controlled;

1. the tablet weighing and feeding device is provided with a grinding box and a weighing balance, wherein the weighing balance is installed and connected to an opening at the upper left end of the grinding box, and a hinge is formed between the middle part of the weighing balance and the grinding box, so that various tablet raw materials can be weighed conveniently, the tablet raw materials can be poured stably conveniently and conveniently, the tablet raw materials can be fed and used conveniently, and the accurate proportioning is facilitated during the later processing, and the influence on the quality of tablets is avoided;

2. the tablet grinding box is provided with a tablet grinding disc and a rotating rod, the middle part of the tablet grinding disc is fixedly connected with the rotating rod, the rotating rod drives the tablet grinding disc to swing and rotate in the grinding box through a first motor, so that tablet raw materials on the grinding box can be conveniently ground by the tablet grinding disc, and tablets are ground into powder and then leak into a mixing box through uniform meshes on the lower surface of the grinding box to be mixed and stirred, so that the fineness of ground tablet powder can be conveniently improved, and later-stage stirring and processing are facilitated;

3. the mixing box is provided with a rotating shaft and a sealing device, the rotating shaft forms a rotating structure in the mixing box, the monomers of the rotating shaft are connected with each other through the meshing of a rotating gear and a toothed belt for linkage, so that the stirring blades are conveniently driven to stir, various tablet powders are conveniently and fully mixed, meanwhile, the mixing box rotates in the supporting shell through an adjusting gear, the stirring efficiency is improved, and the sealing device is connected with the lower end of the mixing box in a clamping manner, so that the blanking is conveniently controlled and the use is convenient;

4. be equipped with and extrude conveying case and spiral conveying pole, it all has the installation on the lower extreme front side and the right side of regulating box to extrude the conveying case, thereby be convenient for extrude the not equidimension tablet of size as required, spiral conveying pole carries out the spiral conveying to tablet mixing powder and extrudes, be convenient for extrude fast and be the piece, powder conveying board rotates in the inside of regulating box simultaneously, the convenience is to powder rotatory conveying, the opening part through on the regulating box conveys the required inside of extruding the conveying case, convenient production extrudes the tablet of different shapes size, and convenient to use.

Drawings

FIG. 1 is a schematic top sectional view of the present invention;

FIG. 2 is a schematic front sectional view of the present invention;

FIG. 3 is an enlarged view of the structure at A in FIG. 2 according to the present invention;

FIG. 4 is a schematic view of a sectional structure in plan view of the regulating box and the powder transfer plate according to the present invention;

fig. 5 is a schematic view showing the entire construction of the powder transfer plate of the present invention;

FIG. 6 is a schematic view of the overall structure of the support housing of the present invention;

FIG. 7 is a schematic top sectional view of the grinding box of the present invention;

FIG. 8 is a schematic view of the overall structure of the sealing device of the present invention;

FIG. 9 is a schematic top sectional view of the grinding box and the weighing balance of the present invention.

In the figure: 1. a support housing; 2. an adjusting gear; 3. a connecting shaft; 4. grinding a box; 5. a rotating shaft; 6. a tablet grinding pan; 7. rotating the rod; 8. a mixing box; 9. an extrusion transfer box; 10. an extrusion molding port; 11. a screw transfer rod; 12. installing a shaft; 13. a driven gear; 14. a connecting gear; 15. a rotating gear; 16. a toothed belt; 17. a first motor; 18. a stirring blade; 19. a second motor; 20. a sealing device; 2001. a support plate; 2002. a leak-proof clamping block; 2003. fixing a limit shell; 21. an electric telescopic rod; 22. a limiting blanking groove; 23. an adjusting box; 24. a third motor; 25. a powder delivery plate; 26. rotating the disc; 27. an adjusting disk; 28. a leak-proof baffle plate; 29. a fourth motor; 30. and weighing a balance.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-9, the present invention provides a technical solution: the high-purity multi-material mixing pharmaceutical equipment with the controllable proportion comprises a supporting shell 1, an adjusting gear 2, a connecting shaft 3, a grinding box 4, a rotating shaft 5, a tablet grinding disc 6, a rotating rod 7, a mixing box 8, an extrusion conveying box 9, an extrusion forming port 10, a spiral conveying rod 11, a mounting shaft 12, a driven gear 13, a connecting gear 14, a rotating gear 15, a toothed belt 16, a first motor 17, a stirring blade 18, a second motor 19, a sealing device 20, a supporting plate 2001, a leakage-proof clamping block 2002, a fixed limiting shell 2003, an electric telescopic rod 21, a limiting blanking groove 22, an adjusting box 23, a third motor 24, a powder conveying plate 25, a rotating disc 26, an adjusting disc 27, a leakage-proof clamping block 28, a fourth motor 29 and a weighing balance 30.

When the high-purity multi-material mixed pharmaceutical equipment with controllable proportion is used, firstly, as shown in fig. 1, fig. 2, fig. 6 and fig. 9, weights with corresponding weights are placed on a tray on the left side of a weighing balance 30, then tablets are placed on a tray on the right side of the weighing balance 30, when the weighing balance 30 is balanced, the weights on the tray of the weighing balance 30 are taken out, the tablets on the tray on the right side of the weighing balance 30 are poured into a grinding box 4, other tablets are added in the same method, the proportion of the tablets is accurately controlled, the use is prevented from being influenced, then a switch of a first motor 17 is turned on, the first motor 17 drives a rotating rod 7 to rotate, the rotating rod 7 is of an L-shaped structure, so that the rotating rod 7 drives the grinding plate 6 to swing and rotate in the grinding box 4, the tablets are ground, the lower surface of the grinding box 4 is of a hollowed-shaped structure, the mesh size is uniform, so that the grinding of the tablet powder is more uniform, and the qualified ground tablet powder falls into the mixing box 8, so that the lower part is convenient to stir and mix for use;

referring to fig. 2, 7 and 8, the switch of the second motor 19 is turned on, the second motor 19 drives the adjusting gear 2 to rotate, the adjusting gear 2 is meshed with the outer wall of the mixing box 8, so as to drive the mixing box 8 to rotate inside the supporting housing 1, when the tablet grinding disk 6 rotates inside the grinding box 4, the tablet grinding disk 6 drives the rotating shaft 5 to rotate inside the mixing box 8, the rotating direction of the output end of the second motor 19 is adjusted and controlled, the rotating direction of the adjusting gear 2 is adjusted and controlled, so as to ensure that the rotating direction of the mixing box 8 is opposite to the rotating direction of the rotating shaft 5, so as to sufficiently stir and mix the tablet powder, after the processing is completed, the electric telescopic rod 21 drives the sealing device 20 to slide downwards, the anti-leakage fixture block 2002 is not clamped with the lower surface of the mixing box 8, so as to facilitate the tablet powder in the mixing box 8 to fall onto the 2001 supporting plate, the blanking is convenient, wherein when the mixing box 8 rotates, the supporting plate 2001 slides on the fixed limiting shell 2003, so that the leak-proof fixture block 2002 is stably clamped with the lower end of the mixing box 8, and the use is convenient;

referring to fig. 2, 3, 4 and 5, the tablet powder is fed to the limit feeding chute 22, and is fed to the powder conveying plate 25 in the adjusting box 23 through the limit feeding chute 22, a switch of the fourth motor 29 is turned on, the fourth motor 29 drives the adjusting disc 27 to rotate, the adjusting disc 27 is meshed with the rotating disc 26, so that the rotating disc 26 is driven to rotate intermittently, the rotation angle is 90 degrees, the tablet powder on the powder conveying plate 25 is conveyed to the extrusion conveying box 9 as required, the upper surface of the powder conveying plate 25 is arranged in an inclined manner, holes are formed in the adjusting box 23 corresponding to the extrusion conveying box 9, and the tablet powder on the powder conveying plate 25 is fed to the extrusion conveying box 9;

extrude simultaneously the upper end opening of conveying case 9 and the lateral wall opening part of regulating box 23 and be the one-to-one setting, avoid keeping stable unloading of the tablet powder that holds on the powder conveying board 25 to extruding conveying case 9, open the switch of third motor 24, third motor 24 rotates spiral conveying rod 11, thereby be convenient for carry out the spiral conveying to the tablet powder, when extruding the extrusion molding mouth 10 department of conveying case 9 outer end, conveniently extrude the tablet, 2 group extrudes the big or small shape difference of extrusion molding mouth 10 on the conveying case 9, thereby be convenient for extrude different tablets as required, conveniently produce the tablet of different shape sizes, facilitate the use, this is the whole process that the high-purity many materials of steerable proportion mix pharmaceutical equipment and use.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A high-purity multi-material mixing pharmaceutical equipment with controllable proportion is characterized in that: the method comprises the following steps:

the grinding device comprises a supporting shell (1), wherein a grinding box (4) is fixedly connected to the inner wall of the upper end of the supporting shell (1), a rotating shaft (5) is connected to the outer wall of the lower end of the grinding box (4) in a sliding mode, and a weighing balance (30) is installed and connected to a spiral conveying rod (11) formed in the upper end of the grinding box (4);

the middle part of the tablet grinding disc (6) is fixedly connected with a rotating rod (7), and the upper end of the rotating rod (7) penetrates through the grinding box (4) and is fixedly connected with the output end of a first motor (17);

the extruding and conveying box (9) penetrates through the right lower side and the front lower side of the supporting shell (1), meanwhile, a spiral conveying rod (11) is rotatably connected inside the extruding and conveying box (9), and one end, located inside the supporting shell (1), of the spiral conveying rod (11) is fixedly connected with the output end of a third motor (24) through a bolt;

the lower end of the sealing device (20) is connected with an electric telescopic rod (21) in an installing mode, and the electric telescopic rod (21) is connected to the inner wall of the upper end of the limiting blanking groove (22) in an installing mode;

powder conveying plate (25), the lower extreme of powder conveying plate (25) is through installation axle (12) fixedly connected with rolling disc (26), and the left side meshing of rolling disc (26) is connected with adjusting disk (27), simultaneously the axis of adjusting disk (27) passes through the output fixed connection of bolt and fourth motor (29).

2. The apparatus of claim 1, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the diameter of the inner wall of the supporting shell (1) is larger than that of the outer wall of the mixing box (8), and the diameter of the inner wall of the mixing box (8) is larger than that of the outer wall of the grinding box (4);

wherein, the upper and lower both ends surface of mixing box (8) all is serration structure, and mixing box (8) are connected for the meshing with the connected mode of adjusting gear (2) to adjusting gear (2) on right side pass through the output fixed connection of connecting axle (3) and second motor (19), simultaneously mixing box (8) constitute revolution mechanic in the inside of support shell (1).

3. The apparatus of claim 1, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: axis of rotation (5) and rotary rod (7) all are "L" style of calligraphy structure, and tablet abrasive disc (6) constitute swing structure in the inside of grinding case (4) through rotary rod (7), simultaneously the lower extreme fixedly connected with stirring vane (18) of axis of rotation (5), and stirring vane (18) constitute revolution mechanic in the inside of mixing box (8).

4. A ratio controllable high purity multi-material mixing pharmaceutical plant according to claim 3, wherein: the upper end of the single body of the rotating shaft (5) is fixedly connected with a rotating gear (15), the single bodies of the rotating gear (15) are distributed in a diamond shape, the single bodies of the rotating gear (15) are meshed with a toothed belt (16) and connected, and the single bodies of the rotating gear (15) and the driven gear (13) form a linkage structure through a connecting gear (14).

5. The apparatus of claim 1, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the single bodies of the extrusion conveying box (9) are vertically arranged, an extrusion molding opening (10) is formed in one end, located on the outer side of the supporting shell (1), of the extrusion conveying box (9), and the size of the opening of the single body on the right side of the extrusion molding opening (10) is larger than that of the opening of the single body at the front end of the extrusion molding opening (10);

wherein, the feed inlet that extrusion moulding mouth (10) is located the inside of support housing (1) is the one-to-one setting with the discharge gate on regulating box (23), and the upper end of regulating box (23) is through material groove (22) fixed connection under spacing on the inner wall of support housing (1), simultaneously the lower extreme of material groove (22) is hopper-shaped structure under spacing.

6. The apparatus of claim 5, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the inside of regulating box (23) is rotated and is connected with powder conveying plate (25) that are fan-shaped structure, and the upper surface of powder conveying plate (25) is the slope setting, simultaneously the both sides fixedly connected with leak protection baffle (28) of powder conveying plate (25), and the high dimension of leak protection baffle (28) is less than the degree of depth size of regulating box (23).

7. The apparatus of claim 6, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the medicine powder conveying plate (25) forms a rotating structure in the adjusting box (23) through the rotating disc (26) and the adjusting disc (27), and the rotating angle of the medicine powder conveying plate (25) is 0-90 degrees.

8. The apparatus of claim 1, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the sealing device (20) comprises a supporting plate (2001), a leakage-proof fixture block (2002) and a fixed limiting shell (2003), wherein the upper end face of the supporting plate (2001) is fixedly connected with the leakage-proof fixture block (2002), the leakage-proof fixture block (2002) is in sliding connection with the fixed limiting shell (2003), and the lower end face of the fixed limiting shell (2003) is fixedly provided with an electric telescopic rod (21);

the support plate (2001) is of a hollow structure, and a leakage-proof fixture block (2002) which is installed and connected on the support plate (2001) is connected with an opening at the lower end of the mixing box (8) in a clamping mode.

9. The apparatus of claim 1, wherein the ratio of the high purity multi-material mixing pharmaceutical equipment is controlled by: the horizontal central axis of the weighing balance (30) is parallel to the horizontal central axis of the grinding box (4), the lower surface of the grinding box (4) is of a hollow structure, and meshes of the lower surface of the grinding box (4) are uniformly arranged.