CN113197875A - Formula and preparation method of wormwood foot patch - Google Patents

Formula and preparation method of wormwood foot patch Download PDF

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Publication number
CN113197875A
CN113197875A CN202110482553.5A CN202110482553A CN113197875A CN 113197875 A CN113197875 A CN 113197875A CN 202110482553 A CN202110482553 A CN 202110482553A CN 113197875 A CN113197875 A CN 113197875A
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wormwood
liquid medicine
radix
foot
formula
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殷月琴
何金花
叶丽丽
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention provides a formula of a wormwood foot patch and a preparation method thereof, belongs to the technical field of wormwood foot patches, and is prepared from the following raw materials: 200 g of wormwood, 100 g of achyranthes root, 100 g of ligusticum wallichii, 100 g of cassia twig, 6 g of clove, 6 g of frankincense, 6 g of myrrh, 100 g of cortex acanthopanacis, 100 g of rhizoma polygonati, 50 g of radix rehmanniae recen, 100 g of prepared rehmannia root, 100 g of radix aucklandiae, 100 g of ginger, 50 g of rhizoma corydalis, 100 g of radix angelicae, 100 g of poria cocos, 15 g of pepper and 500ml of 85% propylene glycol; the traditional Chinese medicine used in the invention is extremely fine powder, is beneficial to absorption, is stuck to Yongquan acupoint on the sole of a foot, and is absorbed through skin under the action of subcutaneous tissue transport protein, and enters the body along with blood circulation; not only has the functions of dredging the channels and collaterals, promoting blood circulation by removing blood stasis and eliminating dampness, but also can nourish yin and tonify the kidney.

Description

Formula and preparation method of wormwood foot patch
Technical Field
The invention relates to the technical field of wormwood foot patches, and particularly relates to a formula of a wormwood foot patch and a preparation method of the wormwood foot patch.
Background
The traditional Chinese medicine considers that the waist and leg pain is related to the kidney, all the medicines for tonifying the kidney are added into the prescription, some people, particularly the old, have poor absorption and can hardly achieve the purpose of tonifying after tonifying, and many people do not like drinking the traditional Chinese medicine, so all the foot pastes are used for making up the defect. The poor circulation of qi and blood at the extremities of the limbs can result in cold hands and feet and severe cold hands and feet, and the root cause is insufficient yang qi.
There are many moxa sticks on the market, but the effect is not very good. Especially, the foot patch is added with a channel-guiding drug to promote blood circulation of feet, so as to guide blood downward and promote blood circulation at the tail end.
Disclosure of Invention
Aiming at the technical defects, the invention aims to provide a formula of a wormwood foot patch and a preparation method thereof, the traditional Chinese medicine used by the invention is extremely fine powder, is beneficial to absorption, is applied to Yongquan point on the sole of a foot, and is absorbed through skin under the action of subcutaneous tissue transport protein and enters the body along with blood circulation; not only has the functions of dredging the channels and collaterals, promoting blood circulation by removing blood stasis and eliminating dampness, but also can nourish yin and tonify the kidney.
In order to solve the technical problems, the invention adopts the following technical scheme:
the formula of the wormwood foot patch is characterized by being prepared from the following raw materials:
200 g of wormwood, 100 g of achyranthes root, 100 g of ligusticum wallichii, 100 g of cassia twig, 6 g of clove, 6 g of frankincense, 6 g of myrrh, 100 g of cortex acanthopanacis, 100 g of rhizoma polygonati, 50 g of radix rehmanniae recen, 100 g of prepared rehmannia root, 100 g of radix aucklandiae, 100 g of ginger, 50 g of rhizoma corydalis, 100 g of radix angelicae, 100 g of poria cocos, 15 g of pepper and 500ml of 85% propylene glycol.
A preparation method of a formula of a wormwood foot patch is characterized by comprising the following steps:
s1, crushing 200 g of wormwood, soaking the wormwood for 30 minutes by using 500ml of 85% propylene glycol, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine, and soaking the crushed clove, frankincense and myrrh by using the liquid medicine at the temperature of 20-25 ℃; soaking for 30 minutes, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine containing volatile oil, wherein the volume of the liquid medicine is not less than 250ml, and obtaining liquid medicine 1;
s2, soaking radix Achyranthis bidentatae, rhizoma Chuanxiong, ramulus Cinnamomi, cortex Acanthopancis, rhizoma Polygonati, radix rehmanniae Preparata, radix aucklandiae, rhizoma Zingiberis recens, radix Angelicae Dahuricae, Poria, rhizoma corydalis, radix rehmanniae, and fructus Capsici in water, decocting for 30 min, filtering to obtain liquid medicine 2, oven drying liquid medicine 2, and granulating;
s3, mixing the dried granules with the liquid medicine 1, preparing pills, wherein each pill is 8-15 g, wrapping the pills with tinfoil paper to prevent volatile components from volatilizing, sealing the pills with wax, and preparing 25-30 pills.
Pharmacology of Chinese medicine
Flos Caryophylli has effects of nourishing liver and kidney, strengthening tendons and bones, dispelling cold, relieving pain, and promoting blood circulation.
Clove and chuanxiong rhizome have strong blood circulation promoting, stasis removing and warming and activating properties, and are effective in treating numbness and arthralgia of joints.
Ramulus Cinnamomi warms and unblocks meridians, and helps yang and regulate qi.
Prepared rehmannia root, radix rehmanniae Praeparata has the effects of enriching blood, nourishing yin, promoting the production of body fluid, replenishing essence and benefiting marrow.
Huang Jing is mainly used to nourish yin of liver and kidney, so it is not dried.
The achyranthes root is neutral in nature, enters kidney and liver meridians, and has the effects of promoting blood circulation to remove blood stasis, strengthening muscles and bones, inducing diuresis to treat stranguria, tonifying liver and kidney, drawing blood downward and warming and invigorating kidney yang.
The propylene glycol has water solubility and fat solubility, and both the fat-soluble and water-soluble effective components in the Chinese medicinal decoction pieces can be dissolved out, and simultaneously, the propylene glycol can be used as a solvent in the formula, has the effects of penetration promotion and absorption enhancement.
The invention has the beneficial effects that: the traditional Chinese medicine used in the invention is extremely fine powder, is beneficial to absorption, is stuck to Yongquan acupoint on the sole of a foot, and is absorbed through skin under the action of subcutaneous tissue transport protein, and enters the body along with blood circulation; not only has the functions of dredging the channels and collaterals, promoting blood circulation by removing blood stasis and eliminating dampness, but also can nourish yin and tonify the kidney.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The formula of the wormwood foot patch is prepared from the following raw materials:
200 g of wormwood, 100 g of achyranthes root, 100 g of ligusticum wallichii, 100 g of cassia twig, 6 g of clove, 6 g of frankincense, 6 g of myrrh, 100 g of cortex acanthopanacis, 100 g of rhizoma polygonati, 50 g of radix rehmanniae recen, 100 g of prepared rehmannia root, 100 g of radix aucklandiae, 100 g of ginger, 50 g of rhizoma corydalis, 100 g of radix angelicae, 100 g of poria cocos, 15 g of pepper and 500ml of 85% propylene glycol.
A preparation method of a formula of a wormwood foot patch comprises the following steps:
s1, crushing 200 g of wormwood, soaking the wormwood for 30 minutes by using 500ml of 85% propylene glycol, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine, and soaking the crushed clove, frankincense and myrrh by using the liquid medicine at the temperature of 20-25 ℃; soaking for 30 minutes, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine containing volatile oil, wherein the volume of the liquid medicine is not less than 250ml, and obtaining liquid medicine 1;
s2, soaking radix Achyranthis bidentatae, rhizoma Chuanxiong, ramulus Cinnamomi, cortex Acanthopancis, rhizoma Polygonati, radix rehmanniae Preparata, radix aucklandiae, rhizoma Zingiberis recens, radix Angelicae Dahuricae, Poria, rhizoma corydalis, radix rehmanniae, and fructus Capsici in water, decocting for 30 min, filtering to obtain liquid medicine 2, oven drying liquid medicine 2, and granulating;
s3, mixing the dried granules with the liquid medicine 1, preparing pills, wherein each pill is 8-15 g, wrapping the pills with tinfoil paper to prevent volatile components from volatilizing, sealing the pills with wax, and preparing 25-30 pills.
Yang qi is the origin of human production, and qi is transported by blood to the whole body, and poor circulation of qi and blood at the extremities will result in cold hands and feet, and severe cold hands and feet, the root cause being yang qi deficiency. The medicine bag has the functions of warming and recuperating kidney yang, warming and activating meridian, promoting qi and blood circulation, dispelling cold and relieving pain, and eliminating dampness.
Before use, the fixing adhesive is stuck on the Yongquan acupoint to prevent displacement and is also contacted with the skin for absorption. Is applied to Yongquan acupoint on sole of foot, and the medicine is absorbed transdermally under the action of subcutaneous tissue transport protein and enters into body along with blood circulation. The ascending of qi and blood of a human body and the ascending of qi and blood to the head can cause the problems of dizziness, headache, blood pressure rise and the like, and the descending of blood can achieve the effect of improving dizziness and assisting in reducing blood pressure.
The achyranthes and the folium artemisiae argyi have the functions of guiding blood downward, warming and invigorating kidney yang, and warming and activating meridians.
Typical cases
The normal value of the rheumatic factor is 0-20 IU/ml, and the rheumatic factor of a rheumatoid arthritis patient is generally more than 80.
First case and rheumatism
Name: wear a certain, sex: female, age: 55; joint swelling, pain, inflexibility, stiffness;
the rheumatism factor before using the ointment is 103 IU/ml;
after 1 month of use, the rheumatic factor is 82 IU/ml;
after 2 months of use, the rheumatic factor is 67 IU/ml;
after 3 months of use, the rheumatic factor is 51 IU/ml;
the decrease of the rheumatic factors indicates that the disease condition is improved, and the formula of the invention has a therapeutic effect.
Case two, case 2. deficiency-cold of spleen and stomach, prolapse of lumbar intervertebral disc
Name: yin certain, sex: female, age: 52; deficiency-cold of the spleen and stomach, lumbar disc herniation.
When the formula of the invention is used, the waist is sore and backache, the patient is full after meals, the stool is loose and thin, and the patient is fat and edema (heavy water dampness);
after 3 weeks of using the formula of the invention, the stool is normal, the weight is reduced by 3 kilograms, and the obesity and edema are better than before (the formula of the invention is beneficial to the effects of water and dampness); the symptoms of soreness of the waist and backache are relieved after 1 month.
In case III, the lumbar intervertebral disc is protruded, one foot has numbness and pain, and sometimes the patient can not sleep
Name: certain populus, sex: male, age: 63;
after the formula of the invention is used for 1 week, the pain is relieved, and the sleep is improved, (the product has the functions of relieving pain and soothing the nerves);
after 3 months of use of the formula disclosed by the invention, the numbness of feet is relieved, and the mobility of waist and legs is recovered to a certain extent.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (2)

1. The formula of the wormwood foot patch is characterized by being prepared from the following raw materials:
200 g of wormwood, 100 g of achyranthes root, 100 g of ligusticum wallichii, 100 g of cassia twig, 6 g of clove, 6 g of frankincense, 6 g of myrrh, 100 g of cortex acanthopanacis, 100 g of rhizoma polygonati, 50 g of radix rehmanniae recen, 100 g of prepared rehmannia root, 100 g of radix aucklandiae, 100 g of ginger, 50 g of rhizoma corydalis, 100 g of radix angelicae, 100 g of poria cocos, 15 g of pepper and 500ml of 85% propylene glycol.
2. The preparation method of the formula of the wormwood foot patch according to claim 1, which is characterized by comprising the following steps:
s1, crushing 200 g of wormwood, soaking the wormwood for 30 minutes by using 500ml of 85% propylene glycol, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine, and soaking the crushed clove, frankincense and myrrh by using the liquid medicine at the temperature of 20-25 ℃; soaking for 30 minutes, performing ultrasonic treatment for 30 minutes, filtering and collecting liquid medicine containing volatile oil, wherein the volume of the liquid medicine is not less than 250ml, and obtaining liquid medicine 1;
s2, soaking radix Achyranthis bidentatae, rhizoma Chuanxiong, ramulus Cinnamomi, cortex Acanthopancis, rhizoma Polygonati, radix rehmanniae Preparata, radix aucklandiae, rhizoma Zingiberis recens, radix Angelicae Dahuricae, Poria, rhizoma corydalis, radix rehmanniae, and fructus Capsici in water, decocting for 30 min, filtering to obtain liquid medicine 2, oven drying liquid medicine 2, and granulating;
s3, mixing the dried granules with the liquid medicine 1, preparing pills, wherein each pill is 8-15 g, wrapping the pills with tinfoil paper to prevent volatile components from volatilizing, sealing the pills with wax, and preparing 25-30 pills.
CN202110482553.5A 2021-04-30 2021-04-30 Formula and preparation method of wormwood foot patch Pending CN113197875A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015102437A1 (en) * 2014-01-06 2015-07-09 장유경 Mugwort patch complex having moxibustion function
CN107970378A (en) * 2016-10-21 2018-05-01 钟伟权 A kind of Chinese medicine of clearing damp pastes enough
CN110227139A (en) * 2018-03-05 2019-09-13 上海官爱堂药业有限公司 A kind of Radix Salviae Miltiorrhizae strengthens muscles and bones particle and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015102437A1 (en) * 2014-01-06 2015-07-09 장유경 Mugwort patch complex having moxibustion function
CN107970378A (en) * 2016-10-21 2018-05-01 钟伟权 A kind of Chinese medicine of clearing damp pastes enough
CN110227139A (en) * 2018-03-05 2019-09-13 上海官爱堂药业有限公司 A kind of Radix Salviae Miltiorrhizae strengthens muscles and bones particle and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
关志宇: "《药物制剂辅料与包装材料》", 31 January 2017 *

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