CN113181547B - Heart pump with ultrasonic thrombolysis function - Google Patents
Heart pump with ultrasonic thrombolysis function Download PDFInfo
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- CN113181547B CN113181547B CN202110443946.5A CN202110443946A CN113181547B CN 113181547 B CN113181547 B CN 113181547B CN 202110443946 A CN202110443946 A CN 202110443946A CN 113181547 B CN113181547 B CN 113181547B
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Abstract
The invention discloses a heart pump with an ultrasonic thrombolysis function, which comprises a heart pump, an ultrasonic transducer and an ultrasonic signal generation assembly, wherein the ultrasonic transducer is arranged on the heart pump, and the ultrasonic signal generation assembly is connected with the ultrasonic transducer to timely dissolve thrombus by utilizing the ultrasonic cavitation. The heart pump with the ultrasonic thrombolysis function solves the problem of thrombus complication after the heart pump is implanted, reduces the pain of a patient in replacing the heart pump, and has convenient use and good treatment effect.
Description
Technical Field
The invention relates to the field of medical equipment, in particular to a heart pump with an ultrasonic thrombolysis function.
Background
The number of heart donors is far from meeting the requirements of patients with heart failure, and the implantation of an artificial left ventricular assist device (heart pump) is the main solution. However, the problem of thrombus after the heart pump is implanted is always difficult to solve, the clinical application of the heart pump is seriously influenced, and the survival of a patient is endangered.
In the related technology, the problem of the heart pump thrombus is solved by optimizing the structure, the shape and the surface of a pump body, and adopting methods such as drug anticoagulation and the like. The optimized design is difficult to fundamentally inhibit the growth of thrombus, and the patients are easy to have complications such as bleeding after taking anticoagulant drugs for a long time.
Disclosure of Invention
The present invention is directed to solving, at least to some extent, one of the technical problems in the related art.
Therefore, the embodiment of the invention provides the heart pump with the ultrasonic thrombolysis function, which has a simple structure and can dissolve thrombus in time.
The heart pump with ultrasonic thrombolysis function according to the embodiment of the invention comprises: a cardiac pump; an ultrasound transducer disposed on the cardiac pump; an ultrasonic signal generating assembly connected with the ultrasonic transducer.
The heart pump with the ultrasonic thrombolysis function can apply ultrasonic with specific frequency in the heart pump for thrombolysis treatment by combining the ultrasonic transducer and the heart pump, so that the service life of the heart pump is prolonged, the pain of a patient in replacing the heart pump is reduced, and the survival probability of the patient is improved.
In some embodiments, the cardiac pump has a blood inflow end and a blood outflow end, the ultrasound transducers comprising a first ultrasound transducer disposed at the blood inflow end and a second ultrasound transducer disposed at the blood outflow end.
In some embodiments, the first and second ultrasound transducers are both rings.
In some embodiments, the first and second ultrasonic transducers are both circular rings.
In some embodiments, the first ultrasound transducer is disposed on the heart pump by adhesive and the second ultrasound transducer is disposed on the heart pump by adhesive.
In some embodiments, the adhesive is an epoxy adhesive or a silicone adhesive.
In some embodiments, the ultrasound transducer is connected to the ultrasound signal generating assembly by a first wire, the heart pump is connected to an external device by a second wire, and the first wire and the second wire are twisted together so that the first wire and the second wire are led out of the body together.
In some embodiments, the sonothrombolysis heart pump further comprises a conduit comprising an inlet tube connected to the blood inflow end and an artificial blood vessel connected to the blood outflow end.
In some embodiments, the ultrasonic signal generating assembly includes a signal generator and a signal amplifier electrically connected for amplifying the drive signal generated by the signal generator.
Drawings
Fig. 1 is a schematic structural diagram of a heart pump with an ultrasonic thrombolysis function according to the present invention.
Fig. 2 is a schematic diagram of a first ultrasonic transducer of a heart pump with sonothrombolysis of the present invention.
Fig. 3 is a schematic diagram of a second ultrasound transducer of the cardiac pump with sonothrombolysis of the present invention.
Reference numerals:
a heart pump 100 having an ultrasonic thrombolysis function;
a heart pump 1; a blood inflow end 11; a blood outflow end 12; a first conductive line 2; an ultrasonic transducer 3; a first ultrasonic transducer 31; a second ultrasonic transducer 32; an ultrasonic signal generating assembly 4; a signal generator 41; a signal amplifier 42; and a second conductive line 5.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
A heart pump having an ultrasonic thrombolysis function according to an embodiment of the present invention will be described below with reference to fig. 1 to 3.
As shown in fig. 1 to 3, a heart pump 100 with an ultrasonic thrombolysis function according to an embodiment of the present invention includes a heart pump 1, an ultrasonic transducer 3, and an ultrasonic signal generating assembly 41.
The ultrasound transducer 3 is provided on the heart pump 1.
The ultrasonic signal generating assembly 41 is connected with the ultrasonic transducer 3. Thereby, the ultrasonic signal generating unit 41 generates a driving signal, and the driving signal drives the ultrasonic transducer 3 to generate ultrasonic waves.
According to the heart pump 100 with the ultrasonic thrombolysis function, the ultrasonic transducer 3 is arranged on the heart pump 1, and the ultrasonic transducer 3 is combined with the heart pump 1, so that ultrasonic waves with specific frequencies can be generated by the ultrasonic transducer 3 in the heart pump 1, ultrasonic cavitation occurs in a thrombus area growing in the heart pump 1, and the thrombus is torn by energy such as shearing force and micro-jet, so that the thrombus in the heart pump 1 is dissolved, the problem of thrombus complication after the heart pump 1 is implanted is effectively solved, the pain of a patient in replacing the heart pump 1 is reduced, and the death rate of the patient is reduced.
In some embodiments, the cardiac pump 1 has a blood inflow end 11 and a blood outflow end 12, the ultrasound transducer 3 comprises a first ultrasound transducer 31 and a second ultrasound transducer 32, the first ultrasound transducer 31 is disposed on the blood inflow end 11, and the second ultrasound transducer 32 is disposed on the blood outflow end 12. Due to the change of the local flow field, the blood inflow end 11 of the heart pump 1 and the blood outflow end 12 of the heart pump 1 are easy to have thrombus, when the performance parameters (such as flow and pressure) of the heart pump 1 are changed remarkably, it is indicated that thrombus begins to grow on the heart pump 1, the ultrasonic transducer 3 is immediately started to perform thrombolytic treatment, the first ultrasonic transducer 31 is arranged at the left end of the heart pump 1, and the second ultrasonic transducer 32 is arranged at the right end of the heart pump 1, so that the first ultrasonic transducer 31 and the second ultrasonic transducer 32 can perform thrombolytic treatment on the region of the heart pump 1 with thrombus, the treatment effects of the first ultrasonic transducer 31 and the second ultrasonic transducer 32 are improved, the thrombus is cleared in time, and the heart pump 1 can be normally used.
In some embodiments, the first ultrasound transducer 31 is provided on the heart pump 1 by means of adhesive, and the second ultrasound transducer 32 is provided on the heart pump 1 by means of adhesive. Specifically, as shown in fig. 1, the first ultrasonic transducer 31 is attached to the left end of the heart pump 1 by adhesive, and the second ultrasonic transducer 32 is attached to the right end of the heart pump 1 by adhesive, so that the first ultrasonic transducer 31 and the second ultrasonic transducer 32 are fixed to the heart pump 1.
It is to be understood that the mounting between the first ultrasound transducer 31 and the heart pump 1 and the mounting between the second ultrasound transducer 32 and the heart pump 1 are not limited to an adhesive connection, but that other connections, such as a fastener connection, may be used.
In some embodiments, the adhesive is an epoxy adhesive or a silicone adhesive. The first ultrasonic transducer 31 and the second ultrasonic transducer 32 are fixed on the heart pump 1 by epoxy resin glue or silicon rubber, and the acoustic impedance of the epoxy resin glue and the silicon rubber is small, so that the energy loss of ultrasonic transmission in an air gap is avoided, and the thrombolysis efficiency of the first ultrasonic transducer 31 and the second ultrasonic transducer 32 is improved.
In some embodiments, the pump for thrombolysis further comprises a conduit (not shown) including an inlet tube (not shown) connected to the inflow end 11 and an artificial blood vessel (not shown) connected to the outflow end 12. Specifically, as shown in fig. 1, one end of the liquid inlet pipe is arranged at the left end of the heart pump 1, one end of the artificial blood vessel is arranged at the right end of the heart pump 1, and the other end of the liquid inlet pipe and the other end of the artificial blood vessel are both connected with the heart, so that blood is supplied to the heart through the heart pump 1, and the normal operation of the heart is ensured.
In some embodiments, the ultrasound transducer 3 is connected to the ultrasound signal generating assembly 2 through a first lead 2, the heart pump 1 is connected to an external device through a second lead 5, and the first lead 2 and the second lead 5 are wound together, so that the first lead 2 and the second lead 5 are led out of the body together. Therefore, the first conducting wire 2 and the second conducting wire 5 are convenient to comb, and the pain of a patient is relieved.
In some embodiments, the first and second ultrasonic transducers 31, 32 are both rings. Thereby, the first ultrasonic transducer 31 can be arranged on the blood inlet end 11 of the heart pump 1, and the second ultrasonic transducer 32 can be arranged on the blood outlet end 12 of the heart pump 1, so that the therapeutic effect of the first ultrasonic transducer 31 and the second ultrasonic transducer 32 is ensured.
In some embodiments, the first and second ultrasonic transducers 31 and 32 are both circular rings. Therefore, the first ultrasonic energy ring device can be conveniently matched with the outer surface of the blood inlet end 11 of the heart pump 1, the second ultrasonic energy transducer 32 is matched with the outer surface of the blood outlet end 12 of the heart pump 1, ultrasonic waves generated by the first ultrasonic energy transducer 31 and the second ultrasonic energy transducer 32 are transmitted from the inner circumferential surface of the circular arc to the circle center direction of the circular arc, the ultrasonic waves are overlapped between the two circular arcs, and the ultrasonic energy is converged in the annular focal region (the annular focal region is the inner part of the circular ring formed by the two circular arcs), so that the ultrasonic energy is improved, thrombolysis is accelerated, and the treatment effects of the first ultrasonic energy transducer 31 and the second ultrasonic energy transducer 32 are improved.
It is understood that the shapes of the first and second ultrasonic transducers 31 and 32 are not limited thereto, and the first and second ultrasonic transducers 31 and 32 may change their shapes and sizes according to the shape of the heart pump, thereby achieving the purpose that the first and second ultrasonic transducers 31 and 32 are mounted on different types of heart pumps 1 to apply ultrasound and treat.
In some embodiments, the inner diameter of the first ultrasonic transducer 31 is 20mm to 21mm, the outer diameter of the first ultrasonic transducer 31 is 26mm to 27mm, the inner diameter of the second ultrasonic transducer 32 is 13mm to 14mm, and the outer diameter of the first ultrasonic transducer 31 is 19mm to 20 mm. Therefore, the first ultrasonic transducer 31 and the second ultrasonic transducer 32 with different inner and outer diameters can be selected according to the difference of the outer diameters of the outer peripheral surface of 1 and the outer peripheral surface of 2, for example: the inner diameter of the first ultrasonic transducer 31 is 20mm, the outer diameter of the first ultrasonic transducer 31 is 26mm, the inner diameter of the second ultrasonic transducer 32 is 13.75mm, and the outer diameter of the first ultrasonic transducer 31 is 19.75mm, so that the inner peripheral surface of the first ultrasonic transducer is attached to the outer peripheral surface of the blood outflow end 11, the inner peripheral surface of the second ultrasonic transducer 32 is attached to the outer peripheral surface of the blood inflow end 12, and the arrangement of the first ultrasonic transducer 31 and the second ultrasonic transducer 32 is more reasonable.
In some embodiments, the ultrasonic signal generating assembly 41 comprises a signal generator 41 and a signal amplifier 42, and the signal generator 41 and the signal amplifier 42 are connected to amplify the driving signal generated by the signal generator 41.
Specifically, as shown in fig. 1, the signal amplifier 42 is electrically connected to the first and second ultrasonic transducers 31 and 32, respectively, through an ultrasonic transducer connector. Therefore, the signal generator 41 is turned on to generate a driving signal, the driving signal is transmitted to the signal amplifier 42 through a lead, the signal amplifier 42 amplifies the driving signal, and the amplified signal drives the first ultrasonic transducer 31 and the second ultrasonic transducer 32 through the joint of the ultrasonic transducer 3 to generate ultrasonic waves, so that the thrombus is treated.
Therefore, the heart pump 100 with the ultrasonic thrombolysis function according to the example of the present invention has the advantages of simple structure, flexible use, good treatment effect, strong pertinence, etc.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; may be mechanically coupled, may be electrically coupled or may be in communication with each other; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the present disclosure, the terms "one embodiment," "some embodiments," or "some examples" or the like mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present disclosure. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.
Claims (7)
1. A heart pump with sonothrombolysis, comprising:
a heart pump having a blood inflow end and a blood outflow end coaxially disposed;
the ultrasonic transducer is arranged on the heart pump, so that an ultrasonic cavitation phenomenon occurs in a region where thrombus grows in the heart pump, and the thrombus in the heart pump is dissolved; the ultrasonic transducer comprises a first ultrasonic transducer and a second ultrasonic transducer, the first ultrasonic transducer is arranged at the blood inflow end, the inner peripheral surface of the first ultrasonic transducer is attached to the outer peripheral surface of the blood inflow end, the second ultrasonic transducer is arranged at the blood outflow end, the inner peripheral surface of the second ultrasonic transducer is attached to the outer peripheral surface of the blood outflow end, and the first ultrasonic transducer and the second ultrasonic transducer are both rings, so that ultrasonic waves are superposed between the two ultrasonic transducers and converge the ultrasonic energy in an annular focal zone;
an ultrasonic signal generating assembly connected with the ultrasonic transducer.
2. The sonothrombolysis heart pump of claim 1, wherein the first and second ultrasound transducers are both circular rings.
3. The heart pump with sonothrombolysis of claim 1, wherein said first ultrasound transducer is provided on said heart pump by means of glue,
the second ultrasonic transducer is arranged on the heart pump through viscose.
4. The heart pump with ultrasonic thrombolysis function of claim 3, wherein the adhesive is epoxy resin glue or silicon rubber.
5. The heart pump with sonothrombolysis of any one of claims 2-4, further comprising a conduit comprising an inlet tube connected to the blood inflow end and an artificial blood vessel connected to the blood outflow end.
6. The heart pump with thrombolytic function of any of claims 1-4, wherein the ultrasound transducer is connected to the ultrasound signal generating assembly by a first lead, the heart pump is connected to an external device by a second lead, and the first lead and the second lead are twisted together so that the first lead and the second lead are led out of the body together.
7. A cardiac pump with ultrasonic thrombolysis function according to any one of claims 1-4, wherein the ultrasonic signal generation assembly comprises a signal generator and a signal amplifier, the signal generator and the signal amplifier being electrically connected for amplifying the driving signal generated by the signal generator.
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| CN202110443946.5A CN113181547B (en) | 2021-04-23 | 2021-04-23 | Heart pump with ultrasonic thrombolysis function |
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| CN202110443946.5A CN113181547B (en) | 2021-04-23 | 2021-04-23 | Heart pump with ultrasonic thrombolysis function |
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| CN113181547B true CN113181547B (en) | 2022-03-18 |
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Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1642498A (en) * | 2002-02-11 | 2005-07-20 | 黄金－T技术股份有限公司 | Method for preventing thrombus formation |
| CN101269245A (en) * | 2008-05-15 | 2008-09-24 | 上海交通大学 | Ultrasonic motor drive diaphragm type blood pump |
| CN102232856A (en) * | 2010-05-06 | 2011-11-09 | 高春平 | Double-frequency ultrasonic multi-dimensional focused cerebrovascular thrombolytic system |
| CN102793980A (en) * | 2011-05-24 | 2012-11-28 | 重庆融海超声医学工程研究中心有限公司 | Double-frequency focused ultrasound system |
| CN103028540A (en) * | 2012-12-11 | 2013-04-10 | 杭州成功超声设备有限公司 | Ultrasonic tool head |
| CN103768671A (en) * | 2014-01-26 | 2014-05-07 | 江苏大学 | Anti-hemolytic and antithrombotic centrifugal double-ventricle cardio pump |
| CN103977464A (en) * | 2014-06-06 | 2014-08-13 | 清华大学 | Implantable miniature axial blood pump with gradually-changing flow zone at outlet |
| CN104001689A (en) * | 2014-04-30 | 2014-08-27 | 沈孟良 | Annular magnetic ultrasonic transducer applicable to pipeline installation |
| CN104069555A (en) * | 2014-06-27 | 2014-10-01 | 长治市久安人工心脏科技开发有限公司 | Accessory axial-flow type blood pump for heart |
| CN104107503A (en) * | 2014-08-01 | 2014-10-22 | 北京中美联医学科学研究院有限公司 | Intermediate-frequency-modulated low frequency sonophoresis system |
| CN107348990A (en) * | 2017-08-25 | 2017-11-17 | 江西理工大学 | Ultrasound is removed and ties system |
| CN108379603A (en) * | 2018-03-05 | 2018-08-10 | 田耘博 | A kind of ultrasonic wave blood-plasma virus killing method and system |
| CN108498888A (en) * | 2017-02-24 | 2018-09-07 | 李国荣 | The anti-bolt magnetic suspension apex of the heart centrifugal pump of ultrasound |
| CN109475671A (en) * | 2016-07-19 | 2019-03-15 | 心脏器械股份有限公司 | Ventricular assist device and its integrated sensor |
| CN109789253A (en) * | 2016-09-23 | 2019-05-21 | 心脏器械股份有限公司 | Sensor is located at the blood pump on surface of shell |
| CN209060387U (en) * | 2018-01-22 | 2019-07-05 | 重庆海扶医疗科技股份有限公司 | Ultrasonic transducer, focusing ultrasonic therapeutic apparatus |
| CN110251850A (en) * | 2019-05-13 | 2019-09-20 | 中国科学院苏州生物医学工程技术研究所 | A kind of ultrasound thrombolysis probe and ultrasound thrombolysis method |
| EP3581216A1 (en) * | 2018-06-11 | 2019-12-18 | Universität Zürich | Blood pump for mechanical circulatory support for fontan patients |
| CN111658999A (en) * | 2020-06-12 | 2020-09-15 | 广东省人民医院 | Multi-frequency multi-power ultrasonic microbubble noninvasive transdermal drug delivery treatment and real-time ultrasonic visual monitoring system |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100537019C (en) * | 2005-03-23 | 2009-09-09 | 深圳职业技术学院 | Energy conversion method and device for ultrasonic liquid processing |
| CN110650756B (en) * | 2017-05-16 | 2022-12-27 | 心脏器械股份有限公司 | Intra-ventricular flow implantable PV loop system |
| CN110997032A (en) * | 2017-08-18 | 2020-04-10 | 心脏器械股份有限公司 | Thrombus detection and removal using flexible electronic sensors and emitters |
| CN110367943A (en) * | 2019-08-23 | 2019-10-25 | 中国科学技术大学 | Phase array transducer and ultrasound phase-control detection system |
| CN112296014A (en) * | 2020-11-24 | 2021-02-02 | 西北工业大学 | Sound vortex ultrasonic cleaning device |
-
2021
- 2021-04-23 CN CN202110443946.5A patent/CN113181547B/en active Active
Patent Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1642498A (en) * | 2002-02-11 | 2005-07-20 | 黄金－T技术股份有限公司 | Method for preventing thrombus formation |
| CN101269245A (en) * | 2008-05-15 | 2008-09-24 | 上海交通大学 | Ultrasonic motor drive diaphragm type blood pump |
| CN102232856A (en) * | 2010-05-06 | 2011-11-09 | 高春平 | Double-frequency ultrasonic multi-dimensional focused cerebrovascular thrombolytic system |
| CN102793980A (en) * | 2011-05-24 | 2012-11-28 | 重庆融海超声医学工程研究中心有限公司 | Double-frequency focused ultrasound system |
| CN103028540A (en) * | 2012-12-11 | 2013-04-10 | 杭州成功超声设备有限公司 | Ultrasonic tool head |
| CN103768671A (en) * | 2014-01-26 | 2014-05-07 | 江苏大学 | Anti-hemolytic and antithrombotic centrifugal double-ventricle cardio pump |
| CN104001689A (en) * | 2014-04-30 | 2014-08-27 | 沈孟良 | Annular magnetic ultrasonic transducer applicable to pipeline installation |
| CN103977464A (en) * | 2014-06-06 | 2014-08-13 | 清华大学 | Implantable miniature axial blood pump with gradually-changing flow zone at outlet |
| CN104069555A (en) * | 2014-06-27 | 2014-10-01 | 长治市久安人工心脏科技开发有限公司 | Accessory axial-flow type blood pump for heart |
| CN104107503A (en) * | 2014-08-01 | 2014-10-22 | 北京中美联医学科学研究院有限公司 | Intermediate-frequency-modulated low frequency sonophoresis system |
| CN109475671A (en) * | 2016-07-19 | 2019-03-15 | 心脏器械股份有限公司 | Ventricular assist device and its integrated sensor |
| CN109789253A (en) * | 2016-09-23 | 2019-05-21 | 心脏器械股份有限公司 | Sensor is located at the blood pump on surface of shell |
| CN108498888A (en) * | 2017-02-24 | 2018-09-07 | 李国荣 | The anti-bolt magnetic suspension apex of the heart centrifugal pump of ultrasound |
| CN107348990A (en) * | 2017-08-25 | 2017-11-17 | 江西理工大学 | Ultrasound is removed and ties system |
| CN209060387U (en) * | 2018-01-22 | 2019-07-05 | 重庆海扶医疗科技股份有限公司 | Ultrasonic transducer, focusing ultrasonic therapeutic apparatus |
| CN108379603A (en) * | 2018-03-05 | 2018-08-10 | 田耘博 | A kind of ultrasonic wave blood-plasma virus killing method and system |
| EP3581216A1 (en) * | 2018-06-11 | 2019-12-18 | Universität Zürich | Blood pump for mechanical circulatory support for fontan patients |
| CN110251850A (en) * | 2019-05-13 | 2019-09-20 | 中国科学院苏州生物医学工程技术研究所 | A kind of ultrasound thrombolysis probe and ultrasound thrombolysis method |
| CN111658999A (en) * | 2020-06-12 | 2020-09-15 | 广东省人民医院 | Multi-frequency multi-power ultrasonic microbubble noninvasive transdermal drug delivery treatment and real-time ultrasonic visual monitoring system |
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| CN113181547A (en) | 2021-07-30 |
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Effective date of registration: 20220812 Address after: Room 112, 1st Floor, Building 6, Yard 26, Yongwang West Road, Daxing Biomedical Industry Base, Zhongguancun Science and Technology Park, Daxing District, Beijing 102600 (cluster registration) Patentee after: Beijing Heqinghechuang Medical Technology Co., Ltd. Address before: 100084 Tsinghua Yuan, Beijing, Haidian District Patentee before: TSINGHUA University |