CN113180823A - Optical fiber conduit cooling system capable of removing fluid bubbles - Google Patents

Optical fiber conduit cooling system capable of removing fluid bubbles Download PDF

Info

Publication number
CN113180823A
CN113180823A CN202110484243.7A CN202110484243A CN113180823A CN 113180823 A CN113180823 A CN 113180823A CN 202110484243 A CN202110484243 A CN 202110484243A CN 113180823 A CN113180823 A CN 113180823A
Authority
CN
China
Prior art keywords
optical fiber
bubble
pipeline
cooling system
sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110484243.7A
Other languages
Chinese (zh)
Inventor
金慧杰
曹鹏
夏良道
陈新蕾
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Jialiang Medical Technology Co ltd
Original Assignee
Hangzhou Jialiang Medical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Jialiang Medical Technology Co ltd filed Critical Hangzhou Jialiang Medical Technology Co ltd
Priority to CN202110484243.7A priority Critical patent/CN113180823A/en
Publication of CN113180823A publication Critical patent/CN113180823A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids

Abstract

The invention relates to an optical fiber conduit cooling system capable of removing fluid bubbles, which comprises an optical fiber conduit; the optical fiber conduit is only composed of an optical fiber and a sleeve sleeved outside the optical fiber, a plurality of spacing parts are further arranged in an extending mode from the inner wall of the sleeve to the axis direction of the sleeve, a plurality of gaps which extend along the length direction of the sleeve and are not communicated with each other are formed among the optical fiber, the sleeve and the spacing parts, a part of the gaps form a water inlet channel, and the other part of the gaps form a water outlet channel; one end of the water inlet channel is communicated with one end of the water outlet channel, the other end of the water inlet channel is communicated with a cold source, and the other end of the water outlet channel is used for discharging the cold source; the optical fiber conduit in the form of the single sleeve structure facilitates the coaxiality and the straightness of the optical fiber and the sleeve; the present invention also provides a method of eliminating air bubbles from a coolant distribution system that ensures that liquid entering the fiber optic conduit is bubble free.

Description

Optical fiber conduit cooling system capable of removing fluid bubbles
Technical Field
The invention belongs to the field of cooling circulation equipment of medical technical equipment and distribution of cooling liquid, and particularly relates to an optical fiber conduit cooling system capable of removing fluid bubbles.
Background
Tumor hyperthermia is the fifth major tumor therapy following surgery, radiation therapy, chemotherapy, and immunotherapy. The basic principle of tumor thermotherapy is to heat the whole or local part of human body by physical energy to raise the temperature of tumor tissue to effective therapeutic temperature for a certain time, and to utilize the difference of the tolerance of normal tissue and tumor cell to temperature to achieve the therapeutic goal of apoptosis of tumor cell and no damage to normal tissue of body. At present, local heat therapy is mainly adopted for tumor heat therapy in clinic, and the used heat sources are as follows: infrared, hot water bath, hot bath, ultrasonic, radio frequency, microwave, laser, and the like.
In one aspect, precise control of the duration of the heat source and the treatment temperature is required regardless of the heat source used. Therefore, a cooling device and a cooling system are usually added to the tumor thermotherapy device. For example, in the existing laser ablation apparatus, the cooling device is generally composed of an inner tube and an outer tube which are sleeved with each other, the device optical fiber for transmitting the light source is located in the inner tube, a first circulation channel is formed between the optical fiber and the inner tube, a second circulation channel is formed between the inner tube and the outer tube, and the first circulation channel and the second circulation channel can be communicated with each other.
On the other hand, in hyperthermia or laser ablation procedures, ablation probe devices are often designed with very fine channels through which a cold fluid flows. The cold liquid can generate a plurality of bubbles in the flowing process, and when the bubbles pass through the light emitting area of the optical fiber, the light emitting effect of the optical fiber can be influenced; as the number of the bubbles increases, the problems of increase in water resistance and poor circulation of the passage are caused, thereby affecting the cooling effect of the cooling cycle apparatus. For example, in the thermal therapy of tumor using laser fiber, if the air bubble just stays or adheres in the light emitting area of the fiber, the therapeutic effect of fiber ablation is greatly influenced. The cooling effect around the fiber is also poor. In order to solve the problem of bubbles, in the prior art, bubbles are taken out only through the continuous circulating flow of cold liquid without arranging a bubble removing device in a water path; or add an exhaust valve on the periphery fixing base of ablation probe, but this exhaust valve's set position and space volume are extremely limited, can not play the effect of effective exhaust bubble in the superfine circulation pipeline, even cause the gathering of bubble at this exhaust valve department, influence cooling channel's pressure environment.
The conventional cooling device and system have the following disadvantages.
1. The coaxiality of the optical fiber, the inner tube and the outer tube cannot be guaranteed, when the flow velocity of fluid around the optical fiber is increased, the optical fiber is easy to shake, the light emitting part of the optical fiber or the whole inner tube inner wall is easy to be attached, the thermal therapy effect of laser is influenced, and even the failure of the optical fiber conduit is caused.
2. As is well known, thermal treatment needles, ablation needles, etc. are very thin and long structures, and the volume of the corresponding cooling device should be reduced as much as possible in view of the demands of minimally invasive surgery. However, the conventional cooling pipes are required to include 2 types of pipes, i.e., an inner pipe and an outer pipe, which is disadvantageous in that the cooling device is miniaturized and portable. Therefore, how to further reduce the volume of the cooling device to make it enter the human body or brain with less trauma and higher safety is one of the problems that the skilled person is urgently in need of solving.
3. In addition, the cold source needs to perform a continuous circulation flow in a fine pipe during the cooling process. Because of factors such as fluid flow velocity, pressure in the pipe and temperature change, the cold source inevitably generates bubbles when flowing. The existence of the air bubbles causes the interface between air and liquid in the cold liquid, thereby causing the refraction phenomenon of light passing through the cold liquid, affecting the light emitting effect of the optical fiber and further affecting the curative effect. Further, the bubbles may also affect the flow characteristics of the fluid. When the number of bubbles in the pipe increases, the cooling circulation pipe is partially or completely blocked, and thus a poor cooling effect occurs. In addition, if a large amount of bubbles are accumulated in the fluid, the water resistance of the channel is increased, the cooling circulation effect of the cold liquid is caused, and the optical fiber sleeve is even broken. Therefore, bubble elimination has also become a major concern in the cooling system of ablation devices.
Therefore, there is a need for a cooling tube structure with a smaller volume and a more stable cooling capacity, and a cooling liquid distribution system with effective bubble elimination.
Disclosure of Invention
The invention aims to provide an optical fiber conduit cooling system capable of removing fluid bubbles, which greatly reduces the volume of the optical fiber conduit by means of the optical fiber conduit with a single sleeve structure on the premise of meeting the requirement of cold liquid circulation refrigeration, so that the optical fiber conduit cooling system is more easily applicable to minimally invasive surgery such as tumor ablation; meanwhile, a bubble removing device is additionally arranged, so that cooling liquid flowing through the optical fiber conduit is cooling liquid without bubbles, and the success rate of the ablation operation is ensured to a certain extent.
The technical means adopted by the invention are as follows.
A cooling system of a fiber conduit capable of removing fluid bubbles comprises a fiber conduit, wherein the fiber conduit is provided with an optical fiber, a sleeve sleeved outside the optical fiber and a plurality of spacing parts. The spacing part extends from the inner wall of the sleeve to the axis direction of the sleeve, and the axial length of the spacing part is matched with that of the sleeve; the long side of the spacing part close to the axis of the sleeve is hermetically connected with the outer wall of the optical fiber.
A plurality of gaps which extend along the length direction of the sleeve and are not communicated with each other are formed among the optical fibers, the sleeve and the spacing part; a part of the gaps form water inlet channels, and the other part of the gaps form water outlet channels; one end of the water inlet channel is communicated with one end of the water outlet channel, the other end of the water inlet channel is communicated with the cold source, and the other end of the water outlet channel is used for discharging the cold source.
Preferably, the spacer and the sleeve are integrally arranged or separately arranged or combined.
Preferably, the outer wall of the optical fiber is hermetically connected to the long side of the spacer in a line contact or surface contact manner.
Preferably, the distal end of the cannula is sealed with a tubular seal. The inner wall of the sealing element and the outer wall of the optical fiber are sealed to form at least two tube cavities; wherein one of the lumens is communicated with the water inlet channel, and the other lumen is communicated with the water outlet channel; and the two tube cavities are respectively communicated with the outside.
Preferably, the cooling system is communicated with the optical fiber conduit and can remove fluid bubbles, and the cooling system is provided with a water inlet pipeline, a water outlet pipeline and a bubble removing device. One end of the water inlet pipeline is communicated with the cold source box, the other end of the water inlet pipeline is communicated with the cold liquid inlet of the optical fiber conduit, and the cold source box is provided with a heating constant temperature device. One end of the water outlet pipeline is communicated with a cold liquid outlet of the optical fiber conduit, and the other end of the water outlet pipeline is communicated with the recovery box. The bubble removing device is arranged on the water inlet pipeline and comprises a first pipeline and a second pipeline obliquely arranged on the side wall of the first pipeline; the first pipeline is communicated with the upstream of the water inlet pipeline through the second pipeline. The upper end of the first pipeline is communicated with a bubble collecting cavity, and a pressure valve A is arranged on the bubble collecting cavity; the lower end of the first pipeline is communicated with the downstream of the water inlet pipeline; and the first pipeline is provided with a bubble filtering membrane.
Preferably, the flow cross-sectional area of the second pipeline is smaller than the flow cross-sectional area of the first pipeline, the flow cross-sectional area of the water inlet pipeline is smaller than the flow cross-sectional area of the first pipeline, and the flow cross-sectional area of the bubble collecting cavity is larger than the flow cross-sectional area of the first pipeline; and an included angle beta formed by the central line of the second pipeline relative to the central line of the first pipeline is between 0 and 90 degrees.
Preferably, a circulation pipeline is additionally arranged between the cold source box and the recovery box, a cold liquid circulation pump is arranged on the circulation pipeline, and a temperature controller is arranged on the recovery box.
A fluid bubble purging optical fiber conduit cooling system further comprising a method of purging bubbles from a cooling fluid distribution system, the method comprising the steps of.
Firstly, a peristaltic pump is started, cold liquid is pumped into the first pipeline through the second pipeline, and the bubble collecting cavity is partially filled with the cold liquid.
Secondly, the cold liquid flow forms the following two flowing cold liquids under the action of the first pipeline, the bubble collecting cavity and the bubble filtering membrane.
The first cold liquid: is a cold liquid containing a plurality of bubbles; the air bubbles are intercepted by the air bubble filtering membrane, and the first cold liquid and the air bubbles are gathered in the air bubble collecting cavity.
The second cold liquid: the second cold liquid is a cold liquid without bubbles, and is used for cooling the optical fiber conduit after flowing through the bubble filtering membrane.
When the pressure in the cooling system or the pressure in the bubble collecting cavity reaches a certain threshold value, a pressure valve A on the bubble collecting cavity is opened to maintain the pressure balance and exhaust of the cooling system; when the bubbles are discharged or the pressure of the cooling system is balanced, the pressure valve A is automatically closed to maintain the normal operation of the cooling system.
Preferably, the bubble filtration membrane has a multilayer membrane structure.
Compared with the prior art, the invention achieves the following beneficial effects by means of ingenious structural design:
(1) the optical fiber and the sleeve can be firmly fixed together in position relation, and the coaxiality and the straightness of the optical fiber and the sleeve are ensured.
(2) Compared with the assembly relation of the three-layer structure of the optical fiber, the inner tube and the outer tube in the prior art, the optical fiber end cooling device removes the inner tube, and can realize the cooling function of the optical fiber end only by using a single sleeve. The single-sleeve cooling structure effectively reduces the volume of the ablation device, so that when entering a human body/brain, the trauma is smaller, the safety is higher, and a flexible and convenient operation space is provided for minimally invasive surgery. Meanwhile, the production cost is greatly reduced.
(3) The bubble removing device is additionally arranged in the cooling system, has a simple structure, is integrally arranged with the cooling system, can realize bubble removing operation of fine flow fluid without occupying extra space, and ensures the flow stability of the fluid.
(2) The plurality of fluid cavities are used independently, so that the streaming phenomenon between the inflow fluid and the outflow fluid can not occur, the cooling effect is better, and the control of the ablation temperature of the optical fiber is more accurate.
Drawings
FIG. 1 is a simplified diagram of the internal cooling circulation structure of an optical fiber conduit.
Fig. 2A to 2D are cross-sectional views of a-a section in fig. 1.
FIG. 3 is a perspective view of the structure of the integrated sleeve according to the preferred embodiment of the present invention.
FIG. 4A is a schematic view of a fiber optic catheter according to a preferred embodiment of the present invention.
Fig. 4B is an exploded view of fig. 4A.
Fig. 5A is a schematic structural diagram of a split sleeve according to a preferred embodiment of the present invention.
Fig. 5B is a cross-sectional view of section B-B of fig. 5A.
Fig. 5C is a cross-sectional view of section G-G of fig. 5A.
Fig. 5D is a cross-sectional view of section H-H of fig. 5A.
Fig. 6A is a schematic structural diagram of a split sleeve according to another preferred embodiment of the present invention.
Fig. 6B is a cross-sectional view of section D-D of fig. 6A.
Fig. 7A is a schematic structural diagram of a split sleeve according to still another preferred embodiment of the present invention.
Fig. 7B is a cross-sectional view of section F-F of fig. 7A.
Fig. 8 is a diagram of cold liquid distribution in the cooling system of the present invention.
FIG. 9 is an enlarged view of the bubble removing device according to the preferred embodiment of the present invention.
Description of the figure numbers:
optical fiber 10
Sleeve 20
Sleeve body 21
Closed end 22
Spacer 30
Water inlet channel 40
Water outlet channel 50
Water inlet line 60
Water outlet pipe 70
Cold source box 80
Heating thermostat 801
Recovery tank 90
Bubble removing device 100
First pipeline 101
Second pipeline 102
Bubble collecting chamber 1011
Bubble filtering membrane 1012
Pressure valve A
Circulating pump 200
Temperature controller 201
Peristaltic pump 300
A seal 400.
Detailed Description
An object of the present invention is to provide a single-cannula optical fiber catheter with a refrigeration function, which is designed as a single-cannula structure, and in the structure, a cooling circulation water path including both an inlet chamber and an outlet chamber can be formed only by matching the single-cannula structure with an optical fiber, so that the volume of the optical fiber catheter is greatly reduced, and the optical fiber catheter is more easily applicable to minimally invasive surgery such as tumor ablation.
The present invention will be described in detail below with reference to the attached drawings and specific embodiments in the background of tumor hyperthermia technology, wherein the exemplary embodiments and the description are only used for explaining the present invention, but not for limiting the present invention. In addition, for better explaining the creation of the present invention, the proximal end in the present invention is the end of the optical fiber close to the focal tissue, and the end far away from the focal tissue is the distal end.
Fig. 1 and 3 are schematic structural views of the optical fiber catheter. The optical fiber catheter includes an optical fiber 10 and a tubular sleeve 20 sleeved outside the optical fiber 10. The sleeve 20 is further provided with a plurality of spacers 30 extending from the inner wall of the sleeve 20 to the axial direction of the sleeve 20, and the axial length of the spacers 30 is matched with that of the sleeve 20. The long side of the spacer 30 near the axial center of the ferrule 20 is hermetically connected to the outer wall of the optical fiber 10. Accordingly, a plurality of gaps, which do not communicate with each other, are formed between the optical fiber 10, the ferrule 20, and the spacer 30, and extend in the longitudinal direction of the ferrule 20. The number of the gaps is preferably even, for example, the number of the gaps may be set to 2, 4, 6, 8, 10 or 12. When the number of the gaps is even, half of the gaps are used as the water inlet passage 40, and the other half of the gaps are used as the water outlet passage 50. One end of the water inlet channel 40 is communicated with one end of the water outlet channel 50 to ensure the circulating cooling effect of the inlet and outlet cooling liquid; the other end of the water inlet channel 40 is communicated with a cold source, and the other end of the water outlet channel 50 is used for discharging the cold source. The optical fiber conduit in the form of a single sleeve structure facilitates the coaxiality and the straightness of the optical fiber and the sleeve. The optical fiber is constantly in a stable and stable state in the working process, the periphery of the optical fiber can be effectively cooled, and the cooling capacity of the cooling sleeve is ensured; in addition, the traditional inner pipe fitting is omitted, the ablation equipment can be cooled by being close to the cooperation of the single sleeve and the optical fiber, the size of the ablation device is greatly reduced, and the operation process of the minimally invasive surgery is facilitated.
Please refer to FIG. 4A and FIG. 4B. A tubular seal 400 is also provided for use with the single-ferrule optical fiber cooling catheter. The sealing member 400 is used to hermetically connect the ferrule 20 and the optical fiber 10. The shape of the tubular sealing member 400 is not specifically described in the present invention, as long as the stability among the sealing member 400, the ferrule 20 and the optical fiber 10, and the smooth entrance and discharge of the cold liquid are ensured. For example, the sealing element 400, the ferrule 20 and the optical fiber 10 are hermetically connected to satisfy the following conditions: the inner wall of the sealing member 400 and the outer wall of the optical fiber 10 can be sealed to form at least two lumens; and one of the lumens is in communication with the water inlet channel 40 on the one hand and the cold liquid on the other hand; and the other lumen is communicated with the water outlet channel 50 on one hand and can smoothly discharge cold liquid on the other hand.
Based on the design of the optical fiber conduit, the following optimization can be further provided.
Optimizing and designing one: the cross-sectional shape of the sleeve 20 may be circular, quasi-circular or polygonal. As shown in fig. 2A to 2B, the optical fiber guide tube includes an optical fiber 10 and a ferrule 20 in this order from the inside to the outside, the cross-sectional shape of the ferrule 20 is circular, and 4 spacers 30 are integrally provided in the ferrule 20. The optical fiber 10, the ferrule 20 and the spacer 30 form 4 axial gaps that do not communicate with each other.
The form of the spacer 30 may be flexibly changed depending on the cross-sectional shape of the ferrule 20, and the outer wall of the optical fiber 10 and the long side of the spacer 30 may be hermetically connected in line contact or surface contact. In fig. 2A, the outer wall of the optical fiber 10 is hermetically connected to the long side of the spacer 30 in a surface contact manner in such a manner that the outer wall of the optical fiber 10 is hermetically connected to the long side of the spacer 30. As shown in fig. 2B, the cross-sectional shape of the sleeve 20 is circular. In this embodiment, the cross-section of the spacer is nearly triangular, and in this case, the outer wall of the optical fiber 10 and the long side of the spacer 30 are hermetically connected in line contact.
And (5) optimization design II: in the embodiment shown in fig. 2A, the spacer 30 is connected to the optical fiber 10 in a surface contact manner. In this embodiment, the spacer 30 is a single member extending from the inner wall of the sleeve 20 in the axial direction of the sleeve 20, and the spacer 30 and the sleeve are designed integrally. When the user wants to increase the number of gaps, the spacer 30 may be provided separately from the sleeve 20. In this case, the spacer 30 is in the form of a spacer plate. One long side of the spacer is detachably connected to the inner wall of the ferrule 20, and the other long side thereof is detachably connected to the outer wall of the optical fiber 10. The connection of the spacer 30, the ferrule 20 and the optical fiber 10 includes, but is not limited to, adhesion.
And (3) optimization design: in some very small flow channels, it is not easy to process a spacer inside the sleeve, so that the spacer 30, which is originally separately established, can be converted into a self-supporting contact portion naturally formed by line contact or surface contact between the inner wall of the sleeve 20 and the outer wall of the optical fiber 10, and the contact portion can fix the coaxial stability of the optical fiber 10 and the sleeve 20 and can also be used to delimit the water inlet channel and the water outlet channel. As shown in fig. 2C, the inner wall of the sleeve 20 and the outer wall of the optical fiber 10 are sealed in line contact to form 4 line contact portions, and gaps are defined between adjacent line contact portions, and these gaps are not communicated with each other, and can be used as a water inlet channel or a water outlet channel of the cooling liquid. Similarly, in fig. 2D, the number of the surface contact portions is 2. The coaxial self-supporting of the optical fiber 10 and the sleeve 20 is ensured, the structural production in the pipe fitting is omitted, and the production flow is simplified.
And (4) optimizing design: please refer to fig. 4A to 4B, fig. 5A to 5D, fig. 6A to 6B, and fig. 7A to 7B. The sleeve 20 may be provided with a sleeve body 21 and a closed end 22, and the closed end 22 is detachably and hermetically connected to the proximal end of the sleeve body 21. As shown in fig. 5A to 5B, there is provided a structure of the closed end 22 having a U-shaped cross-sectional shape; as also shown in fig. 6A to 6B, a structure is provided in which the closed end 22 has a triangular sectional shape; as shown in fig. 7A to 7B, the closed end 22 has a ball head structure. The closed end 22 has one end for sealing connection with the cannula body 21 and the other end for puncturing. In the tumor thermotherapy, the proper closed end 22 can be flexibly selected for puncture according to the tumor position.
As is well known, in the thermotherapy of tumor, especially in the laser ablation, the optical fiber emits a large amount of heat during operation, and it is urgently needed that a cooling medium flows around the optical fiber in time for effective temperature control. However, because the ablation probe has a very small volume, the channels through which the cooling medium can flow are very small, and bubbles are very easily generated during the fluid flowing process. It is therefore another object of the present invention to provide a cooling system for an optical fiber conduit that is capable of removing fluid bubbles by providing a bubble removal device before the cooling fluid flows through the optical fiber conduit, so as to trap air or bubbles generated in the cooling fluid outside the optical fiber conduit and prevent the air or small bubbles from entering the optical fiber conduit.
In order to achieve the above object, the present invention provides a cooling system for an optical fiber conduit capable of removing fluid bubbles, further comprising a cooling system for removing fluid bubbles, which is in communication with the optical fiber conduit. The shape and other characteristics of the fiber optic catheter are described in detail above and will not be described in detail herein. The specific features and methods of the cooling system are described in detail below with reference to the figures and specific examples.
Fig. 8 shows a diagram of cold liquid distribution in the cooling system of the present invention. The cooling system mainly comprises a water inlet pipeline 60, a water outlet pipeline 70, a cold source box 80, a recycling box 90 and a bubble removing device 100. Wherein, one end of the water inlet pipeline 60 is communicated with the cold source box 80, and the other end is communicated with the cold liquid inlet of the optical fiber conduit; the cold source box 80 is provided with a heating thermostat 801. The heating thermostat 801 may be used to heat the cooling medium to a temperature suitable for the human body and maintain that temperature to prevent irritation of the tissue when the cooling fluid flows through the tissue of the human body. Preferably, the heating thermostat 801 ensures that the temperature of the cooling liquid contacting human tissues should be kept near 37.2 ℃, so that tissue reflection caused by large temperature difference can be effectively avoided. One end of the water outlet pipeline 70 is communicated with the cold liquid outlet of the optical fiber conduit, and the other end is communicated with the recycling bin 90.
Fig. 9 is an enlarged view of the bubble removing device according to a preferred embodiment of the present invention. The bubble removing device 100 is disposed on the water inlet pipe 60, and is preferably disposed on the water inlet pipe 60 after the peristaltic pump 300 and before the fiber optic conduit. The bubble removing device 100 comprises a first pipeline 101 and a second pipeline 102 obliquely arranged on the side wall of the first pipeline 101; and said first conduit 101 communicates upstream with said inlet conduit 60 through said second conduit 102. The lower end of the first pipeline 101 is communicated with the downstream of the water inlet pipeline 60, the upper end of the first pipeline is communicated with a bubble collecting cavity 1011, and a pressure valve A is arranged on the bubble collecting cavity 1011. The first pipeline 101 is further provided with a bubble filtering membrane 1012, and the position of the bubble filtering membrane 1012 is preferentially arranged below the communication between the first pipeline 101 and the second pipeline 102. Meanwhile, the bubble filtering membrane 1012 may be disposed at any position on the water inlet line 60. The bubble filtration membrane 1012 is mainly of a multilayer membrane structure.
In the cooling system, in order to effectively filter or trap bubbles, the flow cross-sectional area of the bubble removing device 100 is set as follows: the flow cross-sectional area of the second pipe 102 is smaller than that of the first pipe 101, the flow cross-sectional area of the water inlet pipe 60 is smaller than that of the first pipe 101, and the flow cross-sectional area of the bubble collecting chamber 1011 is larger than that of the first pipe 101. The cross-sectional flow area of the second conduit 102 is not smaller than the cross-sectional flow area of the water inlet conduit 60. Meanwhile, in order to further ensure that the liquid containing bubbles smoothly enters the bubble collecting chamber 1011 and the bubbles are eliminated, in a preferred embodiment of the present invention, an included angle β formed by the center line of the second pipeline 102 with respect to the center line of the first pipeline 101 is set to 0 ° to 90 °. The bubble collecting cavity 1011 is also provided with a pressure valve A. When the pressure in the cooling system or the pressure in the bubble collecting cavity 1011 reaches a certain threshold, the pressure valve A on the bubble collecting cavity 1011 will be opened to maintain the pressure balance and exhaust of the cooling system; when the bubbles are discharged or the pressure of the cooling system is balanced, the pressure valve A is automatically closed to maintain the normal operation of the cooling system. The measurement of the pressure in the cooling system or the pressure in the bubble collecting chamber 1011 and the adjustment method of the pressure valve a are prior art and will not be described herein.
Further, by providing the bubble removing device 100, the present invention provides a fluid bubble removing optical fiber conduit cooling system, and further comprises a method for removing bubbles from a cooling fluid distribution system, the method comprising the following steps.
Firstly, the peristaltic pump 300 is started to pump the cold liquid into the first pipeline 101 through the second pipeline 102, and the bubble collecting cavity 1011 is partially filled. Due to the inclined arrangement of the second pipeline 102 and the first pipeline 101, the liquid containing bubbles can smoothly flow into the first pipeline 101.
Secondly, the cold liquid flow forms cold liquid in the following two flow directions under the action of the first pipeline 101, the bubble collecting cavity 1011 and the bubble filtering film 1012: the first type of cold liquid is a cold liquid containing a number of bubbles which are intercepted by the bubble filtration membrane 1012 and further trapped within the bubble collection chamber 1011. Since the flow cross section of the bubble collecting chamber 1011 is larger than that of the first pipe 101, bubbles are more likely to gather in the upper space inside the bubble collecting chamber 1011. The second cold liquid is a cold liquid without bubbles, and the second cold liquid is used for cooling the optical fiber conduit.
And thirdly, when the pressure in the cooling system or the pressure in the bubble collecting cavity 1011 or the pressure in the optical fiber conduit reaches a certain threshold value, the pressure valve A on the bubble collecting cavity 1011 is opened, and the bubbles gathered in the bubble collecting cavity 1011 are smoothly discharged. When the bubbles are discharged or the pressure of the cooling system is balanced, the pressure valve A is automatically closed again to maintain the normal operation of the cooling system. In addition, the pressure valve A can also be related to the pressure condition inside the optical fiber conduit, when the pressure inside the optical fiber conduit reaches a certain threshold value, the pressure valve A is opened to maintain the pressure balance of the cooling system, and the rupture phenomenon caused by overlarge pressure inside the optical fiber conduit is effectively avoided.
According to the structural design characteristics of the bubble removing device 100, bubbles generated in the ultra-fine fluid channel or liquid containing bubbles can be effectively intercepted in the bubble collecting cavity 1011, so that the inlet water of the whole cooling system is divided into two cold liquid forms. Wherein the first cold liquid is in the form of a cold liquid containing a plurality of bubbles, and the first cold liquid is intercepted into the bubble collecting cavity 1011; and a second, cold liquid without bubbles is used to cool the fiber conduit. This ensures that water entering the fiber optic conduit does not contain bubbles or that water entering the fiber optic conduit is not susceptible to bubble formation. In addition, the bubble removing device 100 is arranged on the water inlet pipeline 60, so that the exhaust condition of the whole cooling system is easy to adjust or observe, the structure is simple, and the manufacturing cost is low.
Please refer to fig. 8, which is a diagram of the distribution of the cooling liquid in the cooling system of the present invention. As a further optimization design of the optical fiber conduit cooling system capable of removing the fluid bubbles, the invention comprises the following steps: a circulation pipeline is further arranged between the cold source box 80 and the recovery box 90; and a cold liquid circulating pump 200 is arranged on the circulating pipeline. The recycling bin 90 is provided with a temperature controller 201 for detecting and controlling the temperature of the cold liquid in the recycling bin 90. The cold liquid in the recovery tank 90 may be supplemented as a supplement liquid into the cold source tank 80.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes performed by the present specification and drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (9)

1. A fluid bubble purging optical fiber conduit cooling system, comprising an optical fiber conduit having an optical fiber (10) and a ferrule (20) disposed outside the optical fiber (10), and
several spacers (30): the spacer is arranged to extend from the inner wall of the sleeve (20) to the axial direction of the sleeve (20), and the axial length of the spacer (30) is matched with that of the sleeve (20); the long side of the spacing part (30) close to the axis of the sleeve (20) is hermetically connected with the outer wall of the optical fiber (10);
a plurality of gaps which extend along the length direction of the sleeve (20) and are not communicated with each other are formed among the optical fiber (10), the sleeve (20) and the spacing part (30); a part of the gaps form a water inlet channel (40), and the other part of the gaps form a water outlet channel (50);
one end of the water inlet channel (40) is communicated with one end of the water outlet channel (50), the other end of the water inlet channel (40) is communicated with the cold source, and the other end of the water outlet channel (50) is used for discharging the cold source.
2. The fluid bubble purging optical fiber conduit cooling system according to claim 1, wherein the spacer (30) is integral with the sleeve (20) or separate therefrom or a combination thereof.
3. The fluid bubble removing optical fiber conduit cooling system as claimed in claim 1, wherein the outer wall of said optical fiber (10) is hermetically connected to the long side of said spacer portion (30) in a line contact or a surface contact.
4. A fluid bubble purging optical fiber conduit cooling system as claimed in any one of claims 1 to 3, wherein a tubular seal (400) is sealed to the distal end of said sleeve (20);
the inner wall of the sealing element (400) and the outer wall of the optical fiber (10) are sealed to form at least two lumens; wherein one of said lumens communicates with said water inlet passage (40) and the other of said lumens communicates with said water outlet passage (50); and the two tube cavities are respectively communicated with the outside.
5. A fluid bubble purging optical fiber conduit cooling system as claimed in any one of claims 1 to 3, further comprising a fluid bubble purging cooling system in communication with said optical fiber conduit, said cooling system having:
water inlet line (60): one end of the cold source box is communicated with a cold source box (80), the other end of the cold source box is communicated with a cold liquid inlet of the optical fiber conduit, and a heating constant temperature device (801) is arranged on the cold source box (80);
water outlet pipeline (70): one end of the cold liquid recycling device is communicated with the cold liquid outlet of the optical fiber conduit, and the other end of the cold liquid recycling device is communicated with a recycling box (90);
bubble removal device (100): the bubble removing device (100) is arranged on the water inlet pipeline (60) and comprises a first pipeline (101) and a second pipeline (102) obliquely arranged on the side wall of the first pipeline (101); the first line (101) being in upstream communication with the water inlet line (60) through the second line (102); the upper end of the first pipeline (101) is communicated with a bubble collecting cavity (1011), and a pressure valve (A) is arranged on the bubble collecting cavity (1011); the lower end of the first pipeline (101) is communicated with the downstream of the water inlet pipeline (60); and a bubble filtering membrane (1012) is arranged on the first pipeline (101).
6. The cooling system for optical fiber conduits capable of removing fluid bubbles according to claim 5, wherein the flow cross-sectional area of the second pipe (102) is smaller than the flow cross-sectional area of the first pipe (101), the flow cross-sectional area of the water inlet pipe (60) is smaller than the flow cross-sectional area of the first pipe (101), and the flow cross-sectional area of the bubble collecting chamber (1011) is larger than the flow cross-sectional area of the first pipe (101);
the central line of the second pipeline (102) forms an included angle beta between 0 and 90 degrees relative to the central line of the first pipeline (101).
7. The cooling system for optical fiber conduits capable of removing fluid bubbles according to claim 6, wherein a circulation pipeline is further disposed between the cold source box (80) and the recovery box (90), a cold liquid circulation pump (200) is disposed on the circulation pipeline, and a temperature controller (201) is disposed on the recovery box (90).
8. A fluid bubble purging optical fiber conduit cooling system, comprising a method of purging bubbles from a coolant distribution system, the method comprising the steps of:
firstly, starting a peristaltic pump (300), pumping cold liquid into a first pipeline (101) through a second pipeline (102), and partially filling a bubble collecting cavity (1011);
secondly, the cold liquid forms the following two flowing directions of cold liquid under the action of the first pipeline (101), the bubble collecting cavity (1011) and the bubble filtering membrane (1012):
the first cold liquid: is a cold liquid containing a plurality of bubbles; the bubbles are intercepted by the bubble filtering membrane (1012), and the first cold liquid and the bubbles are gathered in a bubble collecting cavity (1011);
the second cold liquid: is a cold liquid without air bubbles, and the second cold liquid is used for cooling the optical fiber conduit after flowing through the air bubble filtering membrane (1012);
thirdly, when the pressure in the cooling system or the pressure in the bubble collecting cavity (1011) reaches a certain threshold value, a pressure valve (A) on the bubble collecting cavity (1011) is opened to maintain the pressure balance and exhaust of the cooling system;
when the bubbles are discharged or the pressure of the cooling system is balanced, the pressure valve (A) is automatically closed to maintain the normal operation of the cooling system.
9. The fluid bubble purging optical fiber conduit cooling system as claimed in claim 8, wherein said bubble filtering membrane (1012) is a multi-layer membrane structure.
CN202110484243.7A 2021-04-30 2021-04-30 Optical fiber conduit cooling system capable of removing fluid bubbles Pending CN113180823A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110484243.7A CN113180823A (en) 2021-04-30 2021-04-30 Optical fiber conduit cooling system capable of removing fluid bubbles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110484243.7A CN113180823A (en) 2021-04-30 2021-04-30 Optical fiber conduit cooling system capable of removing fluid bubbles

Publications (1)

Publication Number Publication Date
CN113180823A true CN113180823A (en) 2021-07-30

Family

ID=76983654

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110484243.7A Pending CN113180823A (en) 2021-04-30 2021-04-30 Optical fiber conduit cooling system capable of removing fluid bubbles

Country Status (1)

Country Link
CN (1) CN113180823A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022228428A1 (en) * 2021-04-30 2022-11-03 杭州佳量医疗科技有限公司 Cooling sleeve and optical fiber catheter having same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022228428A1 (en) * 2021-04-30 2022-11-03 杭州佳量医疗科技有限公司 Cooling sleeve and optical fiber catheter having same

Similar Documents

Publication Publication Date Title
JP6461975B2 (en) Blood oxygenator
US7236694B1 (en) Blood and biological fluid warmer
US7740626B2 (en) Laser induced liquid jet generating apparatus
US4231425A (en) Extracorporeal circuit blood heat exchanger
US5403281A (en) Inline heat exchanger and cardioplegia system
US8545754B2 (en) Radial design oxygenator with heat exchanger
CN109224163B (en) A kind of hollow fiber membrane oxygenator that heat exchange layers are external
EP3329953B1 (en) Apparatus for rapidly cooling or heating the body temperature of a patient
JP2020171791A (en) System for providing local cooling to brain and spinal cord
CN103209722B (en) There is the blood treatment unit of circumferential blood flowing
CN215130032U (en) Optical fiber conduit cooling system capable of removing fluid bubbles
CN113398354B (en) Integrated membrane oxygenator
CN113180823A (en) Optical fiber conduit cooling system capable of removing fluid bubbles
CN113855161A (en) Ureter soft endoscope sheath and continuous circulation type perfusion and suction system
US5951949A (en) Heat exchanger for medical applications
CN111281527A (en) Cryoablation catheter
AU2017259117B2 (en) Recirculating cooling systems for use with energy delivery devices
CN212165881U (en) Cryoablation catheter
CN208678001U (en) A kind of counterflow-preventing at the uniform velocity drainage of cerebrospinal fluid pipe
CN220529990U (en) Guiding sheath
US20220096721A1 (en) Artificial lung device
CN115212027A (en) Intravascular heat exchange balloon catheter and low-temperature brain protection device
JP7310286B2 (en) Oxygenator
US20240033408A1 (en) Extracorporeal life support system with blood recirculation pathway
KR20070087155A (en) Closed blood storing tank

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination