CN113180753B - Bead blanket type room interval perforation progressive repair sheet - Google Patents
Bead blanket type room interval perforation progressive repair sheet Download PDFInfo
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- CN113180753B CN113180753B CN202110474361.XA CN202110474361A CN113180753B CN 113180753 B CN113180753 B CN 113180753B CN 202110474361 A CN202110474361 A CN 202110474361A CN 113180753 B CN113180753 B CN 113180753B
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- perforation
- bead
- plugging
- progressive
- ventricular septum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
Abstract
The invention relates to the technical field of acute myocardial infarction ventricular septal defect, and provides a bead blanket type ventricular septal perforation progressive repair sheet, which comprises the following components: the repairing sheet body is arranged in the chamber interval perforation and comprises a supporting framework and a net-shaped plugging piece arranged on the supporting framework; the net-shaped plugging piece comprises a grid part and a plurality of plugging parts arranged on the grid part at intervals, a plurality of grid holes are arranged on the grid part at intervals, and the plugging parts expand after a set time to plug the grid holes. By enabling the plugging part on the grid part to be expandable, temporary partial plugging is realized after the repair sheet body is arranged in the ventricular septum perforation, so that obviously deteriorated hemodynamics can be improved progressively, excessive pressure is not formed on tissues at the edge of the repair sheet body, fragile tissues are prevented from being damaged, after edema of the tissues subsides to form a firm scar, the volume is gradually increased to completely plug the grid hole along with gradual expansion of the plugging part, the complete plugging effect is achieved, and the treatment effect of acute myocardial infarction ventricular septum perforation is improved.
Description
Technical Field
The invention relates to the technical field of acute myocardial infarction ventricular septal defect repair, in particular to a bead blanket type ventricular septal perforation progressive repair sheet.
Background
The acute myocardial infarction and ventricular septum perforation are caused by acute ischemia, myocardial necrosis or ventricular septum perforation, sudden secondary defect is caused to cause serious disturbance of blood flow dynamics, fragile myocardial tissue which is caused by necrosis or edema is arranged around the myocardial infarction and is supposed to be treated in early stage, but the serious illness state is caused by the blood flow dynamics disturbance, especially the fragile necrotic tissue around the defect cannot be treated in early stage no matter surgical intervention or medical intervention, the defect is completely blocked, but the defect is completely blocked by a traditional device, so that strong blood flow impact force is concentrated at the junction of the occluder and the necrotic tissue, and the occluder cannot be fixed and the fragile tissue which is caused to edema is further damaged.
Accordingly, it is desirable to develop a bead blanket type ventricular septum perforation progressive repair patch for solving at least one of the above-mentioned technical problems.
Disclosure of Invention
The invention aims to provide a bead blanket type room interval perforation progressive repairing sheet so as to improve the plugging effect.
The above object of the present invention can be achieved by the following technical solutions:
the invention provides a bead blanket type room interval perforation progressive repair sheet, which comprises the following components:
the repairing sheet body is arranged in the chamber interval perforation and comprises a supporting framework and a net-shaped plugging piece arranged on the supporting framework, the net-shaped plugging piece comprises a grid part and a plurality of plugging parts arranged on the grid part at intervals, a plurality of grid holes are arranged on the grid part at intervals, and the plugging parts are gradually expanded after set time to gradually plug the grid holes on the grid part.
In some embodiments of the invention, the set time is 5-7 days.
In some embodiments of the invention, the occlusion is a gel that completes gradual expansion within a preset time.
In some embodiments of the invention, the occlusion is an expandable magnetic balloon.
In some embodiments of the invention, the blocking portion is in a rounded spherical configuration.
In some embodiments of the invention, the mesh portion is woven from nitinol wires or nanomaterial pieces.
In some embodiments of the invention, the exterior surface of the prosthetic disc body is sprayed with a coating for anticoagulation, antiplatelet, and avoidance of platelet adhesion.
In some embodiments of the invention, the repair sheet body is threaded within the inter-cell perforation.
In some embodiments of the invention, the repair sheet body comprises a first body and a second body with an annular groove therebetween, the first body and the second body being located on opposite sides of the compartment perforation, respectively, the annular groove being for receiving damaged tissue around the compartment perforation.
In some embodiments of the invention, the repair sheet body is in a disc-shaped structure.
The bead blanket type room interval perforation progressive repairing sheet has the characteristics and advantages that:
the plugging part on the grid part is gradually expandable, so that after the repairing sheet body is arranged in the ventricular septum perforation, the grid holes on the grid part are in a circulation state, temporary partial plugging is realized, the improvement of obviously deteriorated blood flow dynamics is facilitated, excessive pressure is not formed on tissues at the edge of the repairing sheet body, fragile tissues are prevented from being damaged, after the edema of the tissues subsides and the scar is formed, the volume is gradually increased until the grid holes are completely plugged along with the gradual expansion of the plugging part, and the treatment effect of the acute myocardial infarction ventricular septum perforation plugging is further improved.
In conclusion, the pathophysiological change of the acute myocardial retroventricular septal perforation is met by the gradual plugging principle, and the plugging effect of the acute myocardial infarction ventricular septal perforation is improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is apparent that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic view of a mesh part in an initial state according to an embodiment of the present invention;
FIG. 2 is a schematic illustration of a mesh portion after inflation of a occluding portion according to an embodiment of the present invention;
FIG. 3 is a schematic view of a repair sheet body according to an embodiment of the invention;
fig. 4 is a partial schematic view of a mesh portion according to an embodiment of the present invention.
Reference numerals illustrate:
1. repairing the sheet body; 11. a support skeleton; 12. a mesh closure; 121. a grid part; 1211. grid holes; 122. a blocking part; 13. a first body; 14. a second body; 15. an annular groove.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention. Furthermore, features defining "first", "second" may include one or more such features, either explicitly or implicitly. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
As shown in fig. 1 to 4, the present invention provides a bead blanket type ventricular septum perforation progressive repairing sheet, comprising: the repairing sheet body 1, the repairing sheet body 1 is arranged in the room interval perforation, the repairing sheet body 1 comprises a supporting framework 11 and a net-shaped plugging piece 12 arranged on the supporting framework 11, the net-shaped plugging piece 12 comprises a grid part 121 and a plurality of plugging parts 122 arranged on the grid part 121 at intervals, a plurality of grid holes 1211 are arranged on the grid part 121 at intervals, and the plugging parts 122 can expand after a set time to plug the grid holes 1211 on the grid part 121.
It can be understood that by making the plugging portion 122 on the mesh portion 121 expandable, after the prosthetic sheet body 1 is disposed in the ventricular septum perforation, the mesh holes 1211 on the mesh portion 121 are in a circulation state, so as to realize temporary partial plugging, which is helpful for improving significantly deteriorated hemodynamics, but does not form excessive pressure on the tissue at the edge of the prosthetic sheet body 1, so as to avoid damaging the fragile tissue, and after the tissue edema subsides and scar is formed, the volume gradually increases until the mesh holes 1211 are completely plugged along with the gradual expansion of the plugging portion 122, thereby achieving a complete plugging effect and further improving the plugging effect of the ventricular septum perforation of the acute myocardial infarction.
In conclusion, the pathophysiological change of the acute myocardial retroventricular septal perforation is met by the gradual plugging principle, and the plugging effect of the acute myocardial infarction ventricular septal perforation is improved.
In some embodiments of the invention, the set time is 5-7 days. Thus, the volume of the plugging portion 122 gradually increases until the mesh holes 1211 are completely plugged after the plugging portion is gradually expanded, so that a complete plugging effect is achieved, and the plugging effect of the acute myocardial infarction compartment perforation is further improved.
In some embodiments of the invention, the occlusion 122 is an expandable gel. It can be understood that the gel has water absorbability, so that the volume can be gradually increased, the pressure can be dispersed, the pressure of newly infarcted myocardium around ventricular septal defects can be reduced, the volume of the gel is gradually increased in the later stage, and the myocardial tissue around ventricular septal perforations is stabilized, so that the complete blockage is realized, and the blockage effect of acute myocardial infarction ventricular septal perforations is improved.
In some embodiments of the invention, the occlusion 122 is an inflatable magnetic ball. It should be noted that the magnetic ball may be woven from nickel-titanium alloy wires or nano materials, and the magnetic beads or gel beads are intermittently dropped, but the shape still needs a double-disc net structure to be clamped at two ends of the perforation.
In some embodiments of the invention, the blocking portion 122 has a rounded spherical configuration. Thereby, the volume of the plugging portion 122 is gradually increased after expansion until the mesh holes 1211 are completely plugged, thereby achieving a complete plugging effect.
In some embodiments of the present invention, the mesh portion 121 is woven from nitinol wires or nanomaterial pieces. Thereby, the structure of the mesh part 121 is made simpler and more stable.
In some embodiments of the invention, the outer surface of the prosthetic disc body 1 is coated with a coating for anticoagulation, antiplatelet, and prevention of platelet adhesion. Thus, thrombosis is avoided.
In some embodiments of the invention, the repair sheet body 1 is threaded within the inter-cell perforation. Thereby, the installation of the repair sheet body 1 is facilitated.
In some embodiments of the present invention, the repair sheet body 1 comprises a first body 13 and a second body 14, an annular groove 15 is disposed between the first body 13 and the second body 14, the first body 13 and the second body 14 are respectively located at two opposite sides of the ventricular septum perforation, and the annular groove 15 is used for accommodating damaged tissues around the ventricular septum perforation.
In some embodiments of the invention, the repair sheet body 1 has a disc-shaped structure. Thereby, the structure of the repair sheet body 1 is made simpler.
In the description of the present specification, reference to the terms "one embodiment," "some embodiments," "illustrative embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: many changes, modifications, substitutions and variations may be made to the embodiments without departing from the spirit and principles of the invention, the scope of which is defined by the claims and their equivalents.
Claims (10)
1. A bead blanket type ventricular septum perforation progressive repair sheet, comprising:
the repairing sheet body is arranged in the ventricular septum perforation and comprises a supporting framework and a net-shaped plugging piece arranged on the supporting framework, the net-shaped plugging piece comprises a grid part and a plurality of plugging parts arranged on the grid part at intervals, the grid part is provided with a plurality of grid holes at intervals, and after tissue edema subsides scar formation in a set time, the plugging parts gradually expand to progressively plug the grid holes on the grid part.
2. The bead blanket type ventricular septum perforation progressive patch of claim 1, wherein the set time is 5-7 days.
3. The bead blanket type ventricular septum perforation progressive patch of claim 1, wherein the occlusion is a gel that completes gradual expansion within a preset time.
4. The bead blanket type ventricular septum perforation progressive patch of claim 1 wherein the occlusion is an inflatable magnetic sphere.
5. The bead blanket type ventricular septum perforation progressive repair patch of claim 1, wherein the plug is of a rounded spherical configuration.
6. The bead blanket type ventricular septum perforation progressive repair patch of claim 1, wherein the mesh portion is woven from nickel titanium alloy wires or nano-material pieces.
7. The bead blanket type ventricular septum perforation progressive patch of claim 1, wherein the external surface of the patch body is sprayed with a coating for anticoagulation, antiplatelet and platelet adhesion avoidance.
8. The bead blanket type inter-cell perforation progressive repair patch according to claim 1, wherein the repair patch body is threaded within the inter-cell perforation.
9. The bead blanket type ventricular septum perforation progressive repair patch of claim 8, wherein the repair patch body comprises a first body and a second body, an annular groove is provided between the first body and the second body, the first body and the second body are respectively positioned at opposite sides of the ventricular septum perforation, and the annular groove is used for accommodating damaged tissues around the ventricular septum perforation.
10. The bead blanket type ventricular septum perforation progressive repair patch of claim 1, wherein the repair patch body is in a disc-shaped structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110474361.XA CN113180753B (en) | 2021-04-29 | 2021-04-29 | Bead blanket type room interval perforation progressive repair sheet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110474361.XA CN113180753B (en) | 2021-04-29 | 2021-04-29 | Bead blanket type room interval perforation progressive repair sheet |
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| Publication Number | Publication Date |
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| CN113180753A CN113180753A (en) | 2021-07-30 |
| CN113180753B true CN113180753B (en) | 2023-06-09 |
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| CN202110474361.XA Active CN113180753B (en) | 2021-04-29 | 2021-04-29 | Bead blanket type room interval perforation progressive repair sheet |
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Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2714284B1 (en) * | 1993-12-23 | 1996-03-08 | Hubert Petitier | Prosthesis for the closure of ruptures of the cardiac walls, in particular interventricular septal ruptures. |
| US7544213B2 (en) * | 2006-09-12 | 2009-06-09 | Adams Jason P | Inflatable hernia patch |
| US20110288568A1 (en) * | 2008-12-19 | 2011-11-24 | Capuzziello Thomas J | Implantable prosthesis |
| WO2012082581A2 (en) * | 2010-12-13 | 2012-06-21 | Richard Massen | Hernia mesh apparatus and method |
| WO2012158738A1 (en) * | 2011-05-18 | 2012-11-22 | St. Jude Medical Puerto Rico Llc | Improved method and system for closing a vascular hole |
| CN104918565B (en) * | 2012-11-13 | 2018-04-27 | 柯惠有限合伙公司 | plugging device |
| WO2018231815A2 (en) * | 2017-06-12 | 2018-12-20 | Kci Licensing, Inc. | Fabric wound filler |
| CN107890357A (en) * | 2017-12-18 | 2018-04-10 | 苏州茵络医疗器械有限公司 | A kind of perivalvular leakage plugging device |
| CN112426185A (en) * | 2020-12-10 | 2021-03-02 | 上海锦葵医疗器械股份有限公司 | Plugging device containing expandable coating and preparation method thereof |
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| CN113180753A (en) | 2021-07-30 |
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Effective date of registration: 20230516 Address after: 100037, Fu Cheng Road, Beijing, Haidian District, No. 6 Applicant after: THE SIXTH MEDICAL CENTER OF PLA GENERAL Hospital Address before: Room 503, unit 1, building 3, courtyard 3, Xicui Road, Haidian District, Beijing 100089 Applicant before: Dong Wei |
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