CN113171963B - Raw material particle processing device for preparing pregabalin capsules - Google Patents
Raw material particle processing device for preparing pregabalin capsules Download PDFInfo
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- CN113171963B CN113171963B CN202110299067.XA CN202110299067A CN113171963B CN 113171963 B CN113171963 B CN 113171963B CN 202110299067 A CN202110299067 A CN 202110299067A CN 113171963 B CN113171963 B CN 113171963B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/46—Constructional details of screens in general; Cleaning or heating of screens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
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- Combined Means For Separation Of Solids (AREA)
Abstract
The invention discloses a raw material particle processing device for preparing pregabalin capsules, which comprises: the device comprises a device main body, wherein a support is arranged on one side of the device main body, a feed hopper is arranged inside the support, the support is fixedly connected with the device main body, and the feed hopper is fixedly connected with the support; the stirring mechanism is arranged in the support and is fixedly connected with a driving shaft of the equipment main body; the screening mechanism is arranged at the bottom of the stirring mechanism, and extrudes raw materials through the stirring mechanism, so that the screening mechanism screens the materials.
Description
Technical Field
The invention relates to the technical field of pregabalin capsule preparation, in particular to a raw material particle processing device for pregabalin capsule preparation.
Background
Pregabalin belongs to non-gamma-aminobutyric acid (GABA) receptor agonists or antagonists, is a novel calcium channel regulator, and can block voltage-dependent calcium channels and reduce the release of neurotransmitters. The traditional Chinese medicine composition is mainly used for treating neuralgia related to diabetic peripheral neuropathy, postherpetic neuralgia and adjuvant therapy of adult partial epileptic seizure, generalized anxiety disorder, central neuralgia (including neuralgia accompanied by spinal cord injury, stroke and multiple sclerosis) and fibromyalgia.
In the preparation process of the pregabalin capsule, raw materials need to be crushed, the raw materials need to be sieved by a swing granulator after being crushed, so that particles needed to be used are obtained, the raw materials need to be placed into the swing granulator when being sieved, the raw materials form particles and are discharged under the action of the swing granulator, however, because the swing granulator uses a single-layer screen when in work, the raw materials are filtered and screened by a rotating roller through the screen, inconvenient particles are added into the capsule subsequently, and when the swing granulator rotates, the raw materials in the granulator are pushed by the rotating roller and screened from the screen, gaps exist between two adjacent rotating rollers and the materials, partial space between the rotating rollers is wasted, energy consumption is increased, secondly, the screened particles can be attached to the shell of a discharge port, and the particles are adhered to the discharge port due to long-term accumulation, it is inconvenient to discharge the screened particles.
Therefore, a raw material particle processing device for preparing pregabalin capsules is provided.
Disclosure of Invention
The invention aims to provide a raw material particle processing device for preparing pregabalin capsules, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a raw material particle processing device for preparing pregabalin capsules, comprising:
the device comprises a device main body, wherein a support is arranged on one side of the device main body, a feed hopper is arranged inside the support, the support is fixedly connected with the device main body, and the feed hopper is fixedly connected with the support;
the stirring mechanism is arranged in the support and is fixedly connected with a driving shaft of the equipment main body;
the screening mechanism is arranged at the bottom of the stirring mechanism, raw materials are extruded through the stirring mechanism, so that the screening mechanism screens the materials, and the support is positioned below the screening mechanism and is provided with a discharging hopper for discharging;
the cutting mechanism is arranged at the bottom of the screening mechanism and is used for cutting off the screened strip-shaped materials through the rotation of the driving shaft;
the knocking mechanism is arranged on the outer side of the discharging hopper and is used for knocking the side surface of the feeding hopper through the movement of the cutting mechanism so as to discharge materials from the feeding hopper;
the pushing mechanism is installed in the feed hopper, and is lifted through rotation of the driving shaft, so that the material is extruded into the stirring mechanism.
Preferably, the stirring mechanism includes two rolling discs that are connected with the support rotation, two through a plurality of live-rollers fixed connection that is central symmetric distribution between the rolling disc, one of them the pivot and the drive shaft fixed connection of rolling disc, live-rollers and rolling disc all are located the inside of screening mechanism.
Preferably, screening mechanism includes the screen cloth with support fixed connection, the screen cloth is circular-arc, the outside of screen cloth is passed through baffle and support fixed connection for it is sealed relatively between the side of screen cloth and the support.
Preferably, shutdown mechanism includes the cutting net with the screen cloth laminating, two guide posts of the inside fixedly connected with of support, cutting net and guide post sliding connection, the both sides of cutting net are equipped with the sliding shaft with support sliding connection, the tip of sliding shaft is equipped with the inclined plane, the both sides of support are equipped with the sliding column, the bottom fixedly connected with sliding block of sliding column, the bottom surface of sliding block be with inclined plane matched with inclined plane, sliding column and support sliding connection, the outside fixedly connected with cam of drive shaft, the cam can promote the sliding column and slide along the vertical direction of support.
Preferably, the two cams are oppositely distributed.
Preferably, a spring is arranged between the sliding column and the support, and two ends of the spring are respectively fixedly connected with the sliding column and the support.
Preferably, the knocking mechanism comprises a connecting rod fixedly connected with the sliding block, the side face of the support is rotatably connected with a knocking plate through a knocking shaft, and a knocking head is arranged at the end of the knocking plate and fixedly connected with the knocking rod.
Preferably, the pushing mechanism comprises a connecting plate fixedly connected with the driving shaft, a connecting shaft is arranged on one side of the connecting plate and located between the two connecting plates, the connecting shaft is rotatably connected with the connecting rod, a pushing plate is arranged inside the feeding hopper, two sides of the pushing plate are connected with the support in a sliding mode through a pushing rod, the pushing rod is L-shaped and is rotatably connected with the connecting rod.
Preferably, both sides of the lower pressing plate are arc-shaped.
The invention has at least the following beneficial effects:
raw materials are stirred and screened by the stirring mechanism and the screening mechanism, strip-shaped raw materials are cut into particles by the cutting mechanism, the particles on the inner wall of the discharge hopper are discharged by the knocking mechanism, the screening mechanism is filled with the materials by the pressing mechanism, compared with the prior art, when the swing granulator works, a single-layer screen is used, the raw materials are filtered and screened by the screen through the rotating rollers, inconvenient particles are added into the capsule later, when the swing granulator rotates, the raw materials in the granulator are pushed by the rotating rollers and screened from the screen, gaps exist between two adjacent rotating rollers and the materials, partial space between the rotating rollers is wasted, the energy consumption is increased, secondly, the screened particles can be attached to the shell of the discharge port, the particles are adhered to the discharge port due to long-term accumulation, and the particles are inconvenient to be discharged after screening, according to the invention, the cutting net is added at the bottom of the screen, when the screen is used for screening, the cutting net moves along with the rotation of the driving shaft, so that raw materials attached to the single-layer screen are cut off, particles can be conveniently added into the capsule, the gap between the rotating roller and the materials is reduced through the pressing mechanism, the energy consumption is saved, and then the materials attached to the discharging hopper are knocked by the knocking mechanism, so that the materials are knocked and discharged, and the particles are conveniently discharged.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a partial schematic view of the present invention;
FIG. 3 is a partial cross-sectional view of the severing mechanism of the present invention;
FIG. 4 is an enlarged view of area A of FIG. 3;
FIG. 5 is an enlarged view of area B of FIG. 3;
FIG. 6 is a partial cross-sectional view of the hold-down mechanism of the present invention;
fig. 7 is an enlarged view of the region C in fig. 6.
In the figure: 1-a device body; 2-a scaffold; 3-a feed hopper; 4-a stirring mechanism; 5-a drive shaft; 6-screening mechanism; 7-a discharge hopper; 8-a cutting mechanism; 9-a knocking mechanism; 10-a press-down mechanism; 11-a rotating disk; 12-a turning roll; 13-a screen mesh; 14-cutting the net; 15-a guide post; 16-a sliding shaft; 17-a sliding post; 18-a slider; 19-a cam; 20-a spring; 21-a connecting rod; 22-a tapping shaft; 23-a knock plate; 24-a tapping head; 25-a connecting plate; 26-a connecting shaft; 27-a connecting rod; 28-a lower press plate; 29-lower compression bar; 30-baffle plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-7, the present invention provides a technical solution: a raw material particle processing device for preparing pregabalin capsules, comprising:
the device comprises a device main body 1, wherein a support 2 is arranged on one side of the device main body 1, a feed hopper 3 is arranged inside the support 2, the support 2 is fixedly connected with the device main body 1, and the feed hopper 3 is fixedly connected with the support 2;
the stirring mechanism 4 is arranged in the bracket 2, and the stirring mechanism 4 is fixedly connected with a driving shaft 5 of the equipment main body 1;
the screening mechanism 6 is arranged at the bottom of the stirring mechanism 4, and is used for extruding the raw materials through the stirring mechanism 4, so that the screening mechanism 6 screens the materials, and the bracket 2 is positioned below the screening mechanism 6 and is provided with a discharging hopper 7 for discharging;
the cutting mechanism 8 is arranged at the bottom of the screening mechanism 6, and the cutting mechanism 8 cuts off the screened strip-shaped materials through the rotation of the driving shaft 5;
the knocking mechanism 9 is arranged on the outer side of the discharging hopper 7, and through the movement of the cutting mechanism 8, the knocking mechanism 9 knocks the side face of the feeding hopper 3, so that materials are discharged from the feeding hopper 3;
and the pressing mechanism 10 is installed in the feed hopper 3, and the pressing mechanism 10 is lifted through the rotation of the driving shaft 5, so that the materials are extruded into the stirring mechanism 4.
Rabbling mechanism 4 includes two rolling discs 11 of being connected with support 2 rotation, two be central symmetric distribution's live-rollers 12 fixed connection, one of them through a plurality of between the rolling disc 11 the pivot and the 5 fixed connection of drive shaft of rolling disc 11, live-rollers 12 all are located screening mechanism 6's inside with rolling disc 11, and at 1 during operation of equipment main part, 1 inside motor of equipment main part drives drive shaft 5 and rotates, and drive shaft 5 drives rolling disc 11 and rotates, and rolling disc 11 drives live-rollers 12 and rotates, and live-rollers 12 is close to screening mechanism 6, and live-rollers 12 extrudees raw and other materials to screening mechanism 6 in to make things convenient for screening mechanism 6's screening.
The cutting mechanism 8 comprises a cutting net 14 attached to a screen 13, two guide posts 15 are fixedly connected to the inside of the support 2, the cutting net 14 is in sliding connection with the guide posts 15, sliding shafts 16 in sliding connection with the support 2 are arranged on two sides of the cutting net 14, an inclined plane is arranged at the end of each sliding shaft 16, sliding posts 17 are arranged on two sides of the support 2, sliding blocks 18 are fixedly connected to the bottoms of the sliding posts 17, the bottom surfaces of the sliding blocks 18 are inclined planes matched with the inclined planes, the sliding posts 17 are in sliding connection with the support 2, a cam 19 is fixedly connected to the outer side of the driving shaft 5, the cam 19 can push the sliding posts 17 to slide along the vertical direction of the support 2, when the driving shaft 5 rotates, the driving shaft 5 drives the cam 19 to rotate, the cam 19 pushes one of the sliding posts 17 to descend, the sliding posts 17 can push the sliding blocks 18 to descend when descending, the sliding block 18 pushes the sliding shaft 16 to move, the sliding shaft 16 drives the cutting net 14 to slide relative to the screen mesh 13, the cutting net 14 cuts off the long strip-shaped raw material part formed by the screen mesh 13, the processing of particles is convenient, when the driving shaft 5 continues to rotate, the cam 19 on the other side pushes the sliding column 17 on the other side to descend, the sliding column 17 pushes the sliding block 18 to descend, the cutting net 14 is further pushed to move reversely, the raw material is cut off again, and the processing of the particles is convenient.
The two cams 19 are oppositely arranged, so that the cutting net 14 can conveniently cut off the raw material at the bottom of the screen mesh 13.
Be equipped with spring 20 between slip post 17 and the support 2, spring 20's both ends respectively with slip post 17 and support 2 fixed connection, after slip post 17 promoted cutting net 14 motion, when cam 19 breaks away from slip post 17 position, spring 20 resets, and spring 20 promotes cutting net 14 and resets to make things convenient for the screening of granule.
The knocking mechanism 9 comprises a connecting rod 21 fixedly connected with a sliding block 18, the side face of the support 2 is rotatably connected with a knocking plate 23 through a knocking shaft 22, a knocking head 24 is arranged at the end part of the knocking plate 23, the knocking head 24 is fixedly connected with a knocking rod, when the cutting-off mechanism 8 cuts off raw material particles, the sliding block 18 of the cutting-off mechanism 8 pushes the connecting rod 21 to descend, the connecting rod 21 pushes the knocking plate 23 to rotate when descending, the knocking plate 23 pushes the knocking head 24 to rotate, the knocking head 24 knocks the discharging hopper 7, particles attached to the discharging hopper 7 vibrate, the particles are discharged, the particles are conveniently discharged, and the accumulation of the particles is reduced.
The pressing mechanism 10 comprises connecting plates 25 fixedly connected with the driving shaft 5, one side of each connecting plate 25 is provided with a connecting shaft 26, the connecting shaft 26 is positioned between the two connecting plates 25, the outer side of each connecting shaft 26 is rotatably connected with a connecting rod 27, the inside of the feeding hopper 3 is provided with a pressing plate 28, two sides of each pressing plate 28 are in sliding connection with the support 2 through pressing rods 29, each pressing rod 29 is L-shaped, each pressing rod 29 is rotatably connected with the corresponding connecting rod 27, when the driving shaft 5 rotates, the driving shaft 5 drives the connecting plates 25 to rotate, the connecting plates 25 drive the connecting shafts 26 to eccentrically rotate so as to drive the connecting rods 27 to move up and down, when the connecting rods 27 move up and down, the connecting rods 27 drive the pressing plates 28 to move up and down, the pressing plates 28 extrude the materials of the feeding hopper 3 to the position of the stirring mechanism 4, and further ensure that the inside of the stirring mechanism 4 is full of the materials, the energy consumption of the equipment is reduced, and the processing of the particles is convenient.
The both sides of holding down plate 28 are arc, make things convenient for the material to pour into from the top of feeder hopper 3 on the one hand through arc's holding down plate 28, and on the other hand is convenient to the extrusion of material.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (3)
1. A raw material particle processing device for preparing pregabalin capsules is characterized by comprising:
the device comprises a device main body (1), wherein a support (2) is arranged on one side of the device main body (1), a feed hopper (3) is arranged inside the support (2), the support (2) is fixedly connected with the device main body (1), and the feed hopper (3) is fixedly connected with the support (2);
the stirring mechanism (4) is arranged in the support (2), and the stirring mechanism (4) is fixedly connected with a driving shaft (5) of the equipment main body (1);
the screening mechanism (6) is arranged at the bottom of the stirring mechanism (4), raw materials are extruded through the stirring mechanism (4), so that the screening mechanism (6) screens the materials, and the support (2) is positioned below the screening mechanism (6) and is provided with a discharging hopper (7) for discharging;
the cutting mechanism (8) is arranged at the bottom of the screening mechanism (6), and the cutting mechanism (8) cuts off the screened strip-shaped materials through the rotation of the driving shaft (5);
the knocking mechanism (9) is arranged on the outer side of the discharging hopper (7), and the knocking mechanism (9) knocks the side face of the feeding hopper (3) through the movement of the cutting mechanism (8), so that the materials are discharged from the feeding hopper (3);
the pressing mechanism (10) is arranged in the feed hopper (3), and the pressing mechanism (10) is lifted through the rotation of the driving shaft (5) so that the materials are extruded into the stirring mechanism (4),
the screening mechanism (6) comprises a screen (13) fixedly connected with the support (2), the screen (13) is arc-shaped, the outer side of the screen (13) is fixedly connected with the support (2) through a baffle (30), so that the side surface of the screen (13) is relatively sealed with the support (2),
the cutting mechanism (8) comprises a cutting net (14) attached to the screen (13), two guide columns (15) are fixedly connected to the inside of the support (2), the cutting net (14) is in sliding connection with the guide columns (15), sliding shafts (16) in sliding connection with the support (2) are arranged on two sides of the cutting net (14), inclined planes are arranged at the end portions of the sliding shafts (16), sliding columns (17) are arranged on two sides of the support (2), sliding blocks (18) are fixedly connected to the bottoms of the sliding columns (17), the bottom surfaces of the sliding blocks (18) are inclined planes matched with the inclined planes, the sliding columns (17) are in sliding connection with the support (2), cams (19) are fixedly connected to the outer side of the driving shaft (5), and the cams (19) can push the sliding columns (17) to slide along the vertical direction of the support (2),
the two cams (19) are distributed oppositely,
a spring (20) is arranged between the sliding column (17) and the bracket (2), two ends of the spring (20) are respectively fixedly connected with the sliding column (17) and the bracket (2),
the knocking mechanism (9) comprises a connecting rod (21) fixedly connected with the sliding block (18), the side surface of the bracket (2) is rotatably connected with a knocking plate (23) through a knocking shaft (22), a knocking head (24) is arranged at the end part of the knocking plate (23), the knocking head (24) is fixedly connected with the knocking rod,
push down mechanism (10) include with drive shaft (5) fixed connection's connecting plate (25), one side of connecting plate (25) is equipped with connecting axle (26), connecting axle (26) are located between two connecting plates (25), the outside of connecting axle (26) is rotated and is connected with connecting rod (27), the inside of feeder hopper (3) is equipped with holding down plate (28), the both sides of holding down plate (28) are through depression bar (29) and support (2) sliding connection down, depression bar (29) are L shape down, depression bar (29) are rotated with connecting rod (27) and are connected down.
2. The apparatus for processing raw material granules for preparation of pregabalin capsules according to claim 1, wherein: rabbling mechanism (4) include rotate two rolling disc (11) of being connected with support (2), two be central symmetric distribution's live-rollers (12) fixed connection, one of them between rolling disc (11) the pivot and drive shaft (5) fixed connection of rolling disc (11), live-rollers (12) all are located the inside of screening mechanism (6) with rolling disc (11).
3. The raw material granule processing device for pregabalin capsule preparation as claimed in claim 1, wherein: the two sides of the lower pressure plate (28) are arc-shaped.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110299067.XA CN113171963B (en) | 2021-03-20 | 2021-03-20 | Raw material particle processing device for preparing pregabalin capsules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110299067.XA CN113171963B (en) | 2021-03-20 | 2021-03-20 | Raw material particle processing device for preparing pregabalin capsules |
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| CN113171963A CN113171963A (en) | 2021-07-27 |
| CN113171963B true CN113171963B (en) | 2022-06-21 |
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| CN202110299067.XA Active CN113171963B (en) | 2021-03-20 | 2021-03-20 | Raw material particle processing device for preparing pregabalin capsules |
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| EP0485096B1 (en) * | 1990-11-05 | 1995-03-01 | Sumitomo Heavy Industries, Ltd. | Method of making capsules of dehydrated sludge and apparatus therefor |
| CN101249402B (en) * | 2007-11-28 | 2010-11-17 | 张惠明 | Press roll type roller compaction pelletizer |
| CN201263978Y (en) * | 2008-09-22 | 2009-07-01 | 金正道 | Pellet mill for stalk |
| US20120319322A1 (en) * | 2010-12-20 | 2012-12-20 | Shell Oil Company | Particle extrusion |
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| CN208321006U (en) * | 2018-04-28 | 2019-01-04 | 天门通威生物科技有限公司 | A kind of grinding device for Feed Manufacturing |
| CN208627235U (en) * | 2018-08-08 | 2019-03-22 | 中科有为河北生物科技有限公司 | A kind of oscillating granulator for pressed candy production |
| CN209361351U (en) * | 2018-11-07 | 2019-09-10 | 上海华源安徽仁济制药有限公司 | A kind of uniform drug granule granulator |
| CN109865564B (en) * | 2019-02-28 | 2021-11-05 | 宁波心生工业设计有限公司 | High-end apparatus for producing based on optoelectromechanical |
| CN210025903U (en) * | 2019-03-22 | 2020-02-07 | 浙江曼得丽涂料有限公司 | Color particle processing mechanism of acrylic acid high-fiber wire drawing multicolor paint |
| CN210357055U (en) * | 2019-07-12 | 2020-04-21 | 巴州农夫情肥业科技有限公司 | Granular organic potash fertilizer granulator |
| CN210336537U (en) * | 2019-07-29 | 2020-04-17 | 杭州临安鑫烽包装材料有限公司 | Granulation equipment is used in cotton production of electron crosslinked polyethylene bubble |
| CN211866086U (en) * | 2019-12-28 | 2020-11-06 | 石家庄正道动物药业有限公司 | Preparation of traditional chinese medicine granule is with swaing granulation machine for animal |
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