CN113134454A - Drop coating device for sensing electrode - Google Patents

Drop coating device for sensing electrode Download PDF

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Publication number
CN113134454A
CN113134454A CN202010062072.4A CN202010062072A CN113134454A CN 113134454 A CN113134454 A CN 113134454A CN 202010062072 A CN202010062072 A CN 202010062072A CN 113134454 A CN113134454 A CN 113134454A
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China
Prior art keywords
electrode
sensing electrode
dispensing
sensing
dispenser
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Granted
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CN202010062072.4A
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Chinese (zh)
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CN113134454B (en
Inventor
侯宁一
陈志�
张念军
徐浩荣
龚明利
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Shenzhen Guiji Sensing Technology Co ltd
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Shenzhen Guiji Sensing Technology Co ltd
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Priority to CN202010062072.4A priority Critical patent/CN113134454B/en
Priority to CN202210463849.7A priority patent/CN114849967B/en
Priority to CN202210463860.3A priority patent/CN114849968B/en
Publication of CN113134454A publication Critical patent/CN113134454A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/002Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the work consisting of separate articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C13/00Means for manipulating or holding work, e.g. for separate articles
    • B05C13/02Means for manipulating or holding work, e.g. for separate articles for particular articles

Abstract

The present disclosure provides a droplet coating apparatus for a sensing electrode, comprising: a loading device which loads a sensing electrode in a predetermined region; the dispensing device is arranged on the loading device and can move relative to the loading device, and the dispensing device is provided with a shooting device and a dispenser for dispensing at least the sensing electrode to form a sensing layer; the positioning device is used for reading a configuration file comprising electrode parameters and indicating a specified area, and moving the dispensing device to the upper part of the specified area according to the configuration file, so that the shooting device shoots the sensing electrode to obtain an area image comprising the sensing electrode; and the recognition device is configured to acquire the area image, recognize the electrode shape of the sensing electrode by combining the electrode parameters, acquire the central position of the electrode shape as target coordinates according to the electrode shape, and control the dispensing device to move above the target coordinates to perform the dispensing operation.

Description

Drop coating device for sensing electrode
Technical Field
The present disclosure relates to a droplet dispensing apparatus for a sensing electrode.
Background
At present, software such as a key puck and the like, which relates to the automation Android system of the windows system, can realize a plurality of automation operations of computer peripherals such as a mouse, a keyboard and the like by using a peripheral programmable interface provided by an operating system, so that some automation operations are realized in normal household and office computers so as to simplify manual operation, and logic iteration can be added in the execution so as to further improve the automation level.
Drop-on positioning of electrodes of e.g. diabetic CGM devices: the drop coating of the electrode slice is needed to be completed on the electrode slice with the nanometer size through manual positioning.
However, software such as key sprites, which belongs to third-party development products, cannot be reliably applied to production line production, and it is necessary to be able to automatically identify the coordinate position of the calibration electrode sheet in dispensing positioning, and it is also necessary to read files such as position matrix files and industrial coordinate files, which are different from normal household file formats, and in addition, the source code of the third-party software service is not open to the user, so that it cannot be customized to complete a full-automatic production process, and only partial automation can be realized. And the drop coating positioning needs a large amount of complicated manual operation, and the process needs to be repeated for producing each new electrode, thereby wasting time and labor.
Disclosure of Invention
The present disclosure has been made in view of the above-mentioned state of the art, and an object thereof is to provide a dispensing apparatus capable of automatically positioning, dispensing automatically, and dispensing a sensing electrode with high accuracy.
To this end, the present disclosure provides a droplet dispensing apparatus for a sensing electrode, characterized by comprising: a loading device which loads a sensing electrode in a predetermined region; the dispensing device is arranged on the loading device and can move relative to the loading device, and the dispensing device is provided with a shooting device and a dispenser for dispensing at least sensing electrodes to form a sensing layer; a positioning device configured to read a configuration file including electrode parameters and indicating the prescribed area, and move the dispenser above the prescribed area according to the configuration file, so that the photographing apparatus photographs the sensing electrode to obtain an area image including the sensing electrode; and the identification device is configured to be used for acquiring the area image, identifying the electrode shape of the sensing electrode by combining the electrode parameters, acquiring the central position of the electrode shape as target coordinates according to the electrode shape, and controlling the dripping device to move above the target coordinates to perform dripping operation. In the present disclosure, the sensor electrode can be loaded by the loading device, the positioning device controls the dispensing device to move to a predetermined area where the sensor electrode is loaded to perform photographing to obtain an area image, and the recognition module finally recognizes a target position of the sensor electrode in the area image by machine vision and controls the dispensing device to move to the target position to perform dispensing.
In addition, the dispensing apparatus according to the present disclosure optionally further includes a monitoring device for monitoring the loading device, the dispensing device, the positioning device and the identification device, wherein the monitoring device is configured to monitor the execution status of each device and to perform a pause, a termination or a reset operation on the device in the abnormal status. In this case, the monitoring device can automatically handle the abnormal state of the device, and thus, the stability of the dispensing apparatus can be improved.
In addition, in the dispensing apparatus according to the present disclosure, optionally, a correction device that adjusts a distance between the dispenser and the prescribed region based on a region image captured by the photographing apparatus so that the region image includes a complete image of the sensor electrode is further included. This ensures that an area image satisfying the needs of the positioning device is captured.
In addition, in the dispensing apparatus according to the present disclosure, optionally, the loading device is arranged with a sensing electrode array plate including the sensing electrodes. This enables the sensor electrode to be applied by batch dispensing.
In addition, in the dispensing apparatus according to the present disclosure, optionally, the configuration file includes coordinate information for moving the dispenser to an initial position, and information on the length, width, and spacing between the sensing electrodes of the sensing electrode array in the sensing electrode array plate. In this case, the positioning device and the recognition device can control the dispensing device to dispense the sensing electrodes one by one in the sensing electrode array according to the configuration file, so that the sensing electrodes can be dispensed in batches.
Additionally, in the dispensing apparatus of the present disclosure, optionally, the dispenser is configured to move in a horizontal direction and a vertical direction. This allows the position of the dispenser to be adjusted as needed.
In the dispensing apparatus according to the present disclosure, the loading device may be provided with a vacuum holder having a plurality of holes in the predetermined region, and the vacuum holder may be configured to hold the sensor electrode by sucking the sensor electrode array plate. In this case, the pressure of the sensing electrode array plate on one side of the vacuum base is lower than the pressure of the sensing electrode array plate on the other side, so that the sensing electrode array plate can be stably fixed to the surface of the vacuum base by the pressure.
Additionally, in the dispensing apparatus to which the present disclosure relates, optionally, the electrode parameter includes at least one of a size, a shape, or a thickness of the sensing electrode. Thus, the recognition device can recognize the sensing electrode in the area image according to the electrode parameters and perform shape fitting to obtain the electrode shape.
In addition, in the dispensing apparatus according to the present disclosure, the recognition device may acquire coordinate information and scale information in the area image from the area image. This makes it possible to obtain the coordinates of each point in the area image.
In addition, in the dispensing apparatus of the present disclosure, the loading device may further include a vacuum pump for maintaining the vacuum seat. Therefore, the suction force of the vacuum seat to the sensing electrode array plate can be adjusted through the vacuum pump.
According to the present disclosure, a dispensing apparatus capable of automatically positioning, dispensing automatically, and having a sensing electrode with high accuracy can be provided.
Drawings
Embodiments of the present disclosure will now be explained in further detail, by way of example only, with reference to the accompanying drawings, in which:
fig. 1 is a schematic configuration diagram illustrating a droplet applying apparatus according to an embodiment of the present disclosure.
Fig. 2 is a block diagram schematically illustrating a structure of a droplet deposition apparatus according to an embodiment of the present disclosure.
Fig. 3 is a schematic configuration diagram illustrating an operation apparatus of the droplet applying apparatus according to the embodiment of the present disclosure.
Fig. 4 is a schematic structural diagram illustrating a sensing electrode array plate of a droplet deposition apparatus according to an embodiment of the present disclosure.
Fig. 5 is a schematic diagram illustrating an area image captured by a droplet applying device of a droplet applying apparatus according to an embodiment of the present disclosure.
Fig. 6 is a schematic diagram showing the structure of a glucose sensor according to an embodiment of the present disclosure.
The reference numbers illustrate:
1 … dispensing device, 10 … loading device, 11 … vacuum seat, 111 … holes, 12 … sensing electrode array plate, 120 … glucose sensor, 121 … sensing electrode, 122 … reference electrode, 123 … counter electrode, 20 … dispensing device, 21 … dispenser, 30 … positioning device, 31 … region image, 40 … recognition device, 2 … operation device, 3 … external device.
Detailed Description
The present disclosure will be described in further detail below with reference to the accompanying drawings and specific embodiments. In the drawings, the same components or components having the same functions are denoted by the same reference numerals, and redundant description thereof will be omitted.
Fig. 1 is a schematic configuration diagram illustrating a droplet applying apparatus 1 according to an embodiment of the present disclosure. Fig. 2 is a block diagram schematically showing the structure of the droplet deposition apparatus 1 according to the embodiment of the present disclosure.
As shown in fig. 1 and 2, the sensing electrode 121 according to the present disclosure may specifically be a working electrode of the glucose sensor 120, but the present embodiment is not limited thereto, and the sensing electrode 121 may be applied to other monitoring electrodes for physiological parameters, for example, a uric acid detection sensor that can be used for detecting uric acid, a cholesterol monitoring sensor that can be used for detecting cholesterol, and the like, and it is only necessary to replace the sensible reagent in the sensing electrode 121 with a corresponding enzyme that specifically reacts with the target analyte. In addition, in addition to dispensing of the sensing electrode 121, the method of locating and identifying the dispensing location by machine vision in the present disclosure is also applicable in other production processes that require automatic dispensing. In some examples, the dispenser 21 may dispense glucose sensitive reagents. In other examples, the dispenser 21 may dispense something other than a glucose sensitive reagent, such as a semi-permeable membrane solution or the like.
In the present embodiment, the dispensing apparatus 1 of the sensor electrode 121 according to the present disclosure may include a loading device 10, a dispensing device 20, a positioning device 30, and a recognition device 40. The loading device 10 may be equipped with the sensor electrode 121 in a predetermined region. The dispensing device 20 can be arranged on the loading device 10 and can be moved relative to the loading device 10, the dispensing device 20 having a recording device (not shown) and a dispenser 21 for dispensing at least the sensor electrodes 121 to form the sensor layer. The positioning device 30 may be configured to read a configuration file including electrode parameters and indicating a prescribed area, and move the dispensing device 20 above the prescribed area according to the configuration file, so that the photographing apparatus photographs the sensing electrode 121 to obtain an area image 31 including the sensing electrode 121. The recognition device 40 may be configured to acquire the area image 31 and recognize the electrode shape of the sensing electrode 121 in conjunction with the electrode parameters, acquire the center position of the electrode shape as target coordinates according to the electrode shape, and control the dispensing device 20 to move above the target coordinates to perform the dispensing operation.
In the present disclosure, the sensor electrode 121 can be mounted on the mounting device 10, the positioning device 30 controls the dispensing device 20 to move to a predetermined area where the sensor electrode 121 is mounted, and the area image 31 is obtained by photographing, and finally the recognition module recognizes the target position of the sensor electrode 121 in the area image 31 by machine vision, and controls the dispensing device 20 to move to the target position for dispensing, in which case the dispensing apparatus 1 can perform the dispensing operation on the sensor electrode 121 by the cooperation between the devices, and thus, the degree of automation of the dispensing operation can be improved.
In some examples, the dispensing device 1 may have an external device 3 and an operating device 2. In particular, the external device 3 may comprise positioning means 30 and recognition means 40, and the operating device 2 may comprise loading means 10 and dispensing means 20.
In some examples, the external device 3 may include at least one of a computer, a mobile communication device, or a cloud server. In other examples, the positioning apparatus 30 may be embodied as a computer program for positioning. In other examples, the identification means 40 may be implemented as a computer program for identification.
Fig. 3 is a schematic configuration diagram illustrating the operation device 2 of the droplet applying device 1 according to the embodiment of the present disclosure.
As shown in fig. 3, in the present embodiment, the loading device 10 may be equipped with the sensor electrode 121 in a predetermined region. This enables the dispensing device 20 to dispense the sensor electrode 121 mounted on the loading device 10. In some examples, the loading device 10 may be loaded with a drip-application device 20. In other examples, the loading device 10 may have a support for supporting the dispensing device 20. The dispensing device 20 can thus be arranged on the support of the loading device 10. Additionally, in some examples, the loading device 10 may be integrated with the drip coating device 20. In this case, a good fit can be formed between the loading device 10 and the dispensing device 20, whereby the accuracy and stability of the dispensing operation can be improved.
Fig. 4 is a schematic structural diagram illustrating the sensor electrode array plate 12 of the droplet deposition apparatus 1 according to the embodiment of the present disclosure.
As shown in fig. 4, in some examples, the loading device 10 may be arranged with a sensing electrode array plate 12 including sensing electrodes 121. This enables batch dispensing of the sensor electrode 121. In some examples, the sensing electrode array plate 12 may be made of a flexible substrate. In other examples, the flexible substrate may be composed of an insulating material. Specifically, the insulating flexible substrate material may be at least one of Polyimide (PI), polyethylene terephthalate (PET), Parylene (Parylene), silicone, Polydimethylsiloxane (PDMS), polyethylene glycol (PEG), or polytetrafluoroethylene (Teflon), Polyethylene (PE), polypropylene (PP), Polystyrene (PS), polyethylene naphthalate (PEN), and the like. This makes it possible to provide both flexibility and insulation to the sensor electrode 121, and to reduce discomfort after implantation into the body.
In other examples, the sensing electrode array plate 12 may be made of a non-flexible substrate. Specifically, the non-flexible substrate material may be ceramic, polymethyl methacrylate (PMMA), alumina, silica, or the like. In this case, the sensing electrode 121 may have a good supporting property. In addition, the sensing electrode 121 may be coupled to a rigid substrate, such as a rigid needle tip, so that the sensing electrode 121 can be implanted into a body surface (e.g., a superficial skin layer) without an auxiliary implantation device (not shown) such as a needle assist device.
In some examples, the sensing electrodes 121 may be formed on a flexible substrate, thereby forming the sensing electrode array plate 12. Additionally, in some examples, the flexible substrate may be a transparent substrate. In this case, the transparent substrate can highlight the shape color of the sensing electrode 121, and thereby, the reliability of the recognition of the positioning by the positioning device 30 (described later) and the recognition device 40 (described later) can be improved.
In some examples, the sensing electrode 121 may be formed on the flexible substrate through a MEMS process, a photolithography process, an etching process, or the like. Thereby, the sensor electrode array plate 12 can be mass-produced to mass-produce the sensor electrodes 121.
In some examples, the loading device 10 is provided with a vacuum holder 11 having a plurality of holes 111 in a predetermined region, and the vacuum holder 11 is used to suck the sensing electrode array plate 12 to fix the sensing electrodes 121. In this case, the pressure of the sensing electrode array plate 12 on one side of the vacuum base 11 is lower than that on the other side, so that the sensing electrode array plate 12 can be stably fixed to the surface of the vacuum base 11 by the pressure.
In some examples, the holes 111 may be arranged at the edge of the vacuum seat 11. In this case, the edge of the sensing electrode array plate 12 can be sucked through the hole 111 disposed at the edge of the vacuum seat 11, and thus, the influence of the negative pressure on the sensing electrode 121 in the sensing electrode array plate 12 can be reduced.
In other examples, the loading device 10 may have a clamp for clamping the sensing electrode array plate 12. This can further fix the sensor electrode array plate 12, thereby improving the stability of the sensor electrode array plate 12 during the dispensing operation.
In some examples, the loading device 10 may also include a vacuum pump for maintaining the vacuum seat 11. This allows the vacuum pump to adjust the suction force of the vacuum holder 11 to the sensor electrode array plate 12.
In some examples, the loading device 10 may further have a reference portion for obtaining the coordinate information and the scale information in the area image 31 as a reference by the recognition device 40. In some examples, the reference portion may be a pattern on the sensing electrode array plate 12. In other examples, the reference portion may be a pattern on the vacuum pad 11. In this case, the positioning device 30 and the recognition device 40 can easily obtain the coordinate information and the scale information in the area image 31 from the reference portion, and thus the recognition efficiency can be improved.
In some examples, the sensing electrode 121 may be provided with a groove for guiding dispensing. In this case, the grooves can limit the content of the dispensing by the dispenser 21, thereby enabling a better control of the dispensing accuracy. In other examples, the groove may serve as a reference. Thereby, the positioning means 30 and the recognition means 40 can easily derive the coordinate information and the scale information in the area image 31 from the size scale of the groove.
In some examples, the loading device 10 may be an enclosable space and the drip-application device 20 may be disposed within the enclosed space. In this case, the enclosed space may be filled with an inert gas, whereby the possibility of the glucose-sensitive reagent and the components in the air undergoing an oxidation reaction can be reduced. In other examples, the dispensing device 20 may be filled with different compositions of gases at different pressures. Therefore, various different dispensing environments can be manufactured, and different types of dispensing can be adapted.
In the present embodiment, the dispensing device 20 may be disposed on the loading device 10 and may be movable relative to the loading device 10.
In the present embodiment, the dispensing device 20 may have an imaging device and a dispenser 21 for dispensing at least the sensor electrode 121 to form a sensor layer. In this case, the droplet applying apparatus 20 can perform both the imaging of the region where the sensor electrode 121 is located by the imaging device and the droplet applying of the sensor electrode 121 by the droplet applying device 21, thereby improving the efficiency of the droplet applying apparatus 20.
In some examples, the capture device may be a miniature video camera, an optical camera, a digital camera, or the like. In some examples, the camera may be mounted to the side of the dispenser 21. In other examples, the photographing apparatus may be independently provided. Thereby, the photographing apparatus can be more flexibly manipulated. Additionally, in some examples, the capture device may be integrated with the dispenser 21. Thereby, the dispenser 21 and the imaging device can be operated in unison, and the portability of the operation of the dispenser 20 can be improved. In other examples, the dispensing device 20 may have an Automated Optical Inspection (AOI) probe.
In some examples, the dispenser 21 is configured to move in a horizontal direction and a vertical direction. This enables the position of the dispenser 21 to be adjusted as needed. In some examples, the coordinates of the closest end of the dispenser 21 closest to the sensing electrode 121 are the coordinates of the dispenser 21. Thereby, the accuracy of dispensing by the dispenser 21 can be improved. In other examples, the dispenser 21 may be needle-shaped (see fig. 3). This enables micro-dispensing of the sensor electrode 121.
Fig. 5 is a schematic diagram illustrating an area image 31 captured by the droplet application device 20 of the droplet application apparatus 1 according to the embodiment of the present disclosure.
As shown in fig. 5, in the present embodiment, the positioning device 30 may be configured to read a configuration file including electrode parameters and indicating a prescribed area. In this case, the execution content of the positioning device 30 can be controlled by encoding the profile, and thus the positioning device 30 can be controlled by the pre-encoded profile. In some examples, the configuration file may be a location matrix file, an industrial coordinate file, a database file, an image data file, or a text file. In other examples, the dispensing apparatus 1 may have a translation device. In particular, the translation means may read the configuration file through a dedicated interface and reconstruct the logic of the configuration file, thereby enabling the positioning means 30 or the recognition means 40 to execute the instructions in the configuration file. In this case, the translation device can translate various configuration files, so that the compatibility of the dispensing device 1 with various configuration files is improved, and the flexibility of controlling the dispensing device 1 is also improved. In addition, in some examples, various types of configuration files may be read by means of a plug-in program. This can expand the reading range of the profile.
In some examples, the translation apparatus may be implemented by a translator written based on a cross-platform computer programming language (python).
In the present embodiment, the positioning device 30 can move the dispensing device 20 to above the specified area according to the configuration file, so that the photographing apparatus can photograph the sensing electrode 121 to obtain the area image 31 including the sensing electrode 121. In some examples, the defined area may be an area where any one of the sensing electrodes 121 on the sensor array plate is located. Thereby, the area image 31 including the sensing electrode 121 can be completely acquired.
In some examples, the configuration file may include coordinate information for moving the dispenser 21 to an initial position, as well as length, width, and spacing information between the sensing electrodes 121 in the sensing electrode array plate 12 for the array of sensing electrodes 121. In this case, the positioning device 30 and the recognition device 40 can control the dispensing device 20 to dispense the sensing electrodes 121 in the array of sensing electrodes 121 one by one according to the configuration file, and thus, the sensing electrodes 121 can be dispensed in batches.
In some examples, the array of sensing electrodes 121 may be disposed on the sensing electrode array plate 12 in a rectangular array. In other examples, the array of sensing electrodes 121 may be disposed on the sensing electrode array plate 12 in an array of parallelograms, triangles, polygons, or circles. Thus, different positioning modes can be set according to different shapes of the array of the sensing electrodes 121.
In other examples, the configuration file may include coordinates of each sensing electrode 121 in the sensing electrode array plate 12. Thus, the positioning device 30 can accurately move the dispenser 21 to the position of each sensor electrode 121. In addition, in some examples, when the array of sensing electrodes 121 is a rectangular array, the configuration file may include at least coordinates of any one of four corners of the array of sensing electrodes 121. Specifically, the positioning device 30 finds the coordinates of any one of the four corners according to the configuration file, and sequentially positions and photographs the sensing electrodes 121 in the sensing electrode 121 array according to the length and the width of the sensing electrode 121 array in the configuration file and the distance information between the sensing electrodes 121, so that the area images 31 of the sensing electrodes 121 can be obtained in batch.
In some examples, the dispensing apparatus 1 may include a correction device that adjusts the distance between the dispenser 21 and the prescribed area based on the area image 31 captured by the camera so that the area image 31 includes a complete image of the sensing electrode 121. This ensures that the area image 31 satisfying the needs of the positioning device 30 is captured.
In the present embodiment, the recognition device 40 may be configured to acquire the region image 31 and recognize the electrode shape of the sensing electrode 121 in conjunction with the electrode parameters. In this case, the accuracy with which the recognition device 40 recognizes the electrode shape of the sensing electrode 121 can be adjusted by adjusting the electrode parameters in the configuration file, whereby an electrode shape of appropriate accuracy can be acquired as necessary. In particular, the recognition means 40 may be implemented as a machine vision program. In this case, it is possible to obtain the relevant morphological information from the area image 31, convert the morphological information into a digitized signal based on the information such as the pixel distribution, brightness, and color of the area image 31, and perform various calculations on the digitized signal to obtain the target feature. In other examples, the positioning device 30 may also be implemented as a machine vision program.
In some examples, the electrode parameters may include at least one of a size, shape, or thickness of the sensing electrode 121. Thus, the recognition device 40 can recognize the sensing electrode 121 in the area image 31 from the electrode parameters and perform shape fitting to obtain the electrode shape.
In the present embodiment, the recognition device 40 may acquire the center position of the electrode shape as the target coordinate according to the electrode shape, and control the dispensing device 20 to move above the target coordinate to perform the dispensing operation.
In some examples, the recognition device 40 may acquire the coordinate information and the scale information in the area image 31 from the area image 31. This makes it possible to obtain the coordinates of each point in the area image 31.
In some examples, the dispensing apparatus 1 may further include a monitoring device for monitoring the loading device 10, the dispensing device 20, the positioning device 30, and the identification device 40, and for monitoring the execution status of each device and performing a pause, terminate, or reset operation on the device in an abnormal state. In this case, the monitoring device can automatically handle the abnormal state, and thus, the stability of the dispensing apparatus 1 can be improved.
Fig. 6 is a schematic diagram showing the structure of a glucose sensor 120 according to an embodiment of the present disclosure.
As shown in fig. 6, in some examples, the dispensing apparatus 1 may further include a laser cutting device for removing the sensing electrodes 121 on the sensing electrode array plate 12. In this case, the sensor electrodes 121 on the sensor array plate can be cut after dispensing is completed, whereby the individual sensor electrodes 121 can be conveniently formed, and thus the individual glucose sensors 120 can be obtained.
As described above, the glucose sensor 120 may also include a reference electrode 122 and a counter electrode 123 (see FIG. 6).
In this embodiment, reference electrode 122 may form a known and fixed potential difference with interstitial fluid or blood. In this case, the potential difference between the sensing electrode 121 and the tissue fluid or blood can be measured by the potential difference formed between the reference electrode 122 and the sensing electrode 121, so that the voltage generated by the sensing electrode 121 can be accurately grasped.
In addition, in the present embodiment, the sensing electrode 121, the reference electrode 122, and the counter electrode 123 are arranged in a dispersed manner, but the embodiments of the present disclosure are not limited thereto, and may include a side-by-side (parallel) arrangement.
In addition, in the present embodiment, the glucose sensor 120 is not limited to the planar type, and may be a line type, a sensor having stacked electrodes or layered electrodes, and a glucose sensor 120 having coplanar electrodes in which electrodes are disposed on the same plane.
In the present embodiment, as described above, the glucose sensor 120 may include a plurality of contacts (feelers). The number of contacts is equal to the number of electrodes of the glucose sensor 120. The contact and the electrode are connected by a lead (wire).
In the present embodiment, as shown in fig. 6, the number of electrodes of the glucose sensor 120 is three. Accordingly, the glucose sensor 120 includes three contacts (feelers), contact 124, contact 125, and contact 126.
In the present embodiment, the contacts 124, 125, and 126 may each have a disk shape. In other examples, contacts 124, 125, and 126 may also be rectangular, oval, or other irregular shapes.
While the present disclosure has been described in detail in connection with the drawings and examples, it should be understood that the above description is not intended to limit the disclosure in any way. Those skilled in the art can make modifications and variations to the present disclosure as needed without departing from the true spirit and scope of the disclosure, which fall within the scope of the invention.

Claims (10)

1. A dripping and coating device of a sensing electrode is characterized in that,
the method comprises the following steps:
a loading device which loads a sensing electrode in a predetermined region;
the dispensing device is arranged on the loading device and can move relative to the loading device, and the dispensing device is provided with a shooting device and a dispenser for dispensing at least sensing electrodes to form a sensing layer;
a positioning device configured to read a configuration file including electrode parameters and indicating the prescribed area, and move the dispenser above the prescribed area according to the configuration file, so that the photographing apparatus photographs the sensing electrode to obtain an area image including the sensing electrode; and
the recognition device is configured to acquire the area image, recognize the electrode shape of the sensing electrode in combination with the electrode parameters, acquire the central position of the electrode shape as a target coordinate according to the electrode shape, and control the dispenser to move above the target coordinate to perform the dispensing operation.
2. The dispensing apparatus of claim 1, wherein:
and the device also comprises a monitoring device for monitoring the loading device, the dripping device, the positioning device and the identification device, wherein the monitoring device is used for monitoring the execution state of each device and executing pause, termination or reset operation on the device in an abnormal state.
3. The dispensing apparatus of claim 1, wherein:
further comprising a correction device that adjusts the distance between the dispenser and the prescribed area based on an area image captured by the photographing apparatus so that the area image includes a complete image of the sensing electrode.
4. The dispensing apparatus of claim 1, wherein:
the loading device is arranged with a sensing electrode array plate including the sensing electrodes.
5. The dispensing apparatus of claim 4, wherein:
the configuration file includes coordinate information for moving the dispenser to an initial position, and information on the length, width, and spacing between sensing electrodes of the sensing electrode array in the sensing electrode array plate.
6. The dispensing apparatus of claim 1, wherein:
the dispenser is configured to move in a horizontal direction and a vertical direction.
7. The dispensing apparatus of claim 4, wherein:
the loading device is provided with a vacuum seat with a plurality of holes in the specified area, and the vacuum seat is used for adsorbing the sensing electrode array plate so as to fix the sensing electrodes.
8. The dispensing apparatus of claim 1, wherein:
the electrode parameter includes at least one of a size, a shape, or a thickness of the sensing electrode.
9. The dispensing apparatus of claim 1, wherein:
and the identification device acquires the coordinate information and the proportion information in the area image according to the area image.
10. The dispensing apparatus of claim 7, wherein:
the loading device further comprises a vacuum pump for maintaining the vacuum seat.
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CN202010062072.4A CN113134454B (en) 2020-01-20 2020-01-20 Drop coating device for sensing electrode
CN202210463849.7A CN114849967B (en) 2020-01-20 2020-01-20 Dispensing device with reference part
CN202210463860.3A CN114849968B (en) 2020-01-20 2020-01-20 Dispensing apparatus

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FR2280439A1 (en) * 1974-07-29 1976-02-27 Uss Eng & Consult METHOD AND APPARATUS FOR CONTROLLING THE WEIGHT AND THE DISTRIBUTION OF A COATING MATERIAL DEPOSITED CONTINUOUSLY ON A SUPPORT
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AU2018100349A4 (en) * 2017-08-22 2018-05-17 Iris Id Pty Limited Dispensing System
CN109046846A (en) * 2018-10-30 2018-12-21 石家庄辐科电子科技有限公司 A kind of intelligent circuit board paint spraying apparatus based on linear motor
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CN114849967B (en) 2024-04-09

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