CN113134129A

CN113134129A - Infusion pump and infusion pump bubble detection method

Info

Publication number: CN113134129A
Application number: CN202010068202.5A
Authority: CN
Inventors: 左鹏飞; 涂有强; 张鹏
Original assignee: Shenzhen Mindray Scientific Co Ltd
Current assignee: Shenzhen Mindray Scientific Co Ltd
Priority date: 2020-01-20
Filing date: 2020-01-20
Publication date: 2021-07-20

Abstract

The embodiment of the application discloses an infusion pump and an infusion pump bubble detection method; the infusion pump emits ultrasonic waves and collects corresponding ultrasonic signals after the infusion pump is powered on, the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit is determined, the ultrasonic drive circuit and/or the ultrasonic detection circuit is adjusted according to the adjustment information, the bubble state in the infusion tube is determined according to the ultrasonic signals collected after adjustment and a bubble threshold value, and the volume information and/or the bubble alarm information of bubbles are output according to the bubble state.

Description

Infusion pump and infusion pump bubble detection method

Technical Field

The application relates to the technical field of medical treatment, in particular to an infusion pump and an infusion pump bubble detection method.

Background

An existing infusion pump manufacturer generally presets relevant parameters (such as gain) corresponding to the characteristics of specific infusion tube consumables in an infusion pump, and the infusion pump can detect bubbles of the specific infusion tube consumables based on the preset relevant parameters. However, the infusion pump with the set relevant parameters can only be limited to detect bubbles of specific infusion tube consumables, and when the infusion pump needs to support different types of consumables, because the tube diameters of different types or brands of infusion tubes are different, if bubble detection is performed on other different types of infusion tube consumables according to the preset relevant parameters, bubbles in the infusion tube cannot be accurately detected by the bubble detection device, and then leak detection or false detection of the bubbles exists.

Disclosure of Invention

The embodiment of the application provides an infusion pump and an infusion pump bubble detection method, which can be suitable for bubble detection of infusion tubes of different types so as to reduce missing detection or false detection of bubbles.

A first aspect of an embodiment of the present application provides an infusion pump, where the infusion pump is used in cooperation with an infusion tube, the infusion pump includes a peristaltic squeezing mechanism, a processor, and an ultrasonic sensor assembly, and the ultrasonic sensor assembly includes an ultrasonic sensor emitting end, an ultrasonic sensor receiving end, an ultrasonic driving circuit, and an ultrasonic detection circuit; the peristaltic extrusion mechanism comprises a driving mechanism and a pump sheet set; the processor is connected with the transmitting end of the ultrasonic sensor through the ultrasonic driving circuit so as to control the transmitting end of the ultrasonic sensor to transmit ultrasonic waves, the processor is connected with the receiving end of the ultrasonic sensor through the ultrasonic detection circuit so as to receive ultrasonic signals which are acquired by the receiving end of the ultrasonic sensor and are formed by signal processing of the ultrasonic detection circuit, and the driving mechanism drives the pump sheet set to extrude infusion tubes which are arranged along the tube grooves of the infusion tubes of the infusion pump under the control of the processor so as to enable liquid in the infusion tubes to move according to a preset direction;

the processor is used for emitting ultrasonic waves and collecting corresponding ultrasonic signals after the infusion pump is powered on, determining adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit, adjusting the ultrasonic drive circuit and/or the ultrasonic detection circuit according to the adjustment information, determining the state of bubbles in the infusion tube according to the ultrasonic signals collected after adjustment and a bubble threshold value, and outputting volume information and/or bubble alarm information of the bubbles according to the state of the bubbles.

A second aspect of the embodiment of the present application provides a method for detecting bubbles in an infusion pump, the method is applied to an infusion pump, the infusion pump is used in cooperation with an infusion tube, the infusion pump includes a peristaltic squeezing mechanism, a processor and an ultrasonic sensor assembly, and the ultrasonic sensor assembly includes an ultrasonic sensor emitting end, an ultrasonic sensor receiving end, an ultrasonic driving circuit and an ultrasonic detection circuit; the peristaltic extrusion mechanism comprises a driving mechanism and a pump sheet set; the processor is connected with the transmitting end of the ultrasonic sensor through the ultrasonic driving circuit so as to control the transmitting end of the ultrasonic sensor to transmit ultrasonic waves, and the processor is connected with the receiving end of the ultrasonic sensor through the ultrasonic detection circuit so as to receive ultrasonic signals which are acquired by the receiving end of the ultrasonic sensor and are formed by signal processing of the ultrasonic detection circuit; the driving mechanism drives the pump sheet set to extrude an infusion tube arranged along an infusion tube groove of the infusion pump under the control of the processor, so that liquid in the infusion tube moves according to a preset direction, and the method comprises the following steps:

powering on the infusion pump;

transmitting ultrasonic waves and collecting corresponding ultrasonic signals;

determining adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit;

adjusting the ultrasonic driving circuit and/or the ultrasonic detection circuit according to the adjustment information;

determining the bubble state in the infusion tube according to the acquired ultrasonic signal and the bubble threshold value after adjustment;

and outputting the volume information and/or bubble alarm information of the bubbles according to the bubble state.

According to the infusion pump and the infusion pump bubble detection method, the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit is determined by determining the ultrasonic signals received after the infusion pump is electrified, and then the ultrasonic drive circuit and/or the ultrasonic detection circuit are adjusted according to the adjustment information, so that the ultrasonic signals acquired after adjustment are adaptive to the infusion tube consumables used currently, the influence of the infusion tube consumables on the output amplitude of the ultrasonic signals when different infusion tube consumables are adopted in the infusion pump is reduced, the self-adaptive control of the ultrasonic signals is realized, the real-time performance is strong, and the problems of bubble omission and false detection caused by different infusion tube consumables are effectively solved.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

FIG. 1 is a flow chart illustrating steps of a method for detecting air bubbles in an infusion pump according to an embodiment of the present application.

Fig. 2 is a schematic structural diagram of an infusion pump in an embodiment of the present application.

Fig. 3 is a schematic view of the structure of an infusion pump in a further embodiment of the present application.

Fig. 4 is a schematic diagram of an ultrasonic sensor transmitting and receiving ultrasonic signals in an embodiment of the present application.

Fig. 5 is a block diagram of a hardware configuration of a medical device according to an embodiment of the present application.

FIG. 6 is a schematic view of the peristaltic squeezing mechanism and the arrangement of the infusion tube in one embodiment of the present invention.

Fig. 7 is a block diagram of the hardware configuration of an infusion pump in an embodiment of the present application.

Fig. 8 is a schematic view of the bubble type in an embodiment of the present application.

Fig. 9 is a schematic view of the form of a bubble type in a further embodiment of the present application.

FIG. 10 is a schematic view of a bubble type in another embodiment of the present application.

Fig. 11 is a graphical representation of the output amplitude of different classes of infusion tubes in an embodiment of the present application.

Fig. 12 is a diagram illustrating a relationship between output amplitudes corresponding to different transmission frequencies in an embodiment of the present application.

Fig. 13 is a schematic diagram illustrating changes in output amplitude corresponding to different bubble types in an embodiment of the present application.

Fig. 14 is a flowchart of a method for detecting air bubbles in an infusion pump according to an embodiment of the present application.

Detailed Description

In order to make the technical solutions of the present application better understood, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first," "second," and the like in the description and claims of the present application and in the above-described drawings are used for distinguishing between different objects and not for describing a particular order. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

The following describes embodiments of the present application in detail.

Referring to fig. 1, a flowchart illustrating steps of a method for detecting air bubbles in an infusion pump according to an embodiment of the present application is shown. The infusion pump bubble detection method comprises the following steps:

step S100, the infusion pump is powered on.

Referring to fig. 2 and fig. 3, a schematic structural diagram of an infusion pump according to an embodiment of the present application is shown. The infusion pump 20 includes a pump body 210, a display system 160, a peristaltic squeezing mechanism 200 (shown in fig. 6), an infusion tube slot 205, an ultrasound transducer assembly 230, and a pump door 212, wherein the pump door 212 is movably mounted on the pump body 210 to cover the infusion tube slot 205 (shown in fig. 2) for receiving the infusion tube 40, and when the pump door 212 is opened by a user, the infusion tube slot 205 (shown in fig. 3) for receiving the infusion tube 40 is exposed. The pump door 212 has a front side facing the user (outside) and side surfaces that can be used to mate with the dock, as well as top and bottom surfaces that can be used to oppose other infusion pumps (including but not limited to infusion pumps and syringe pumps) in a stacked arrangement.

In some embodiments, the display system 160 is disposed on the pump door 212, and the display system 160 extends from the left side of the center line of the front surface of the pump door 212 to the right side of the center line of the front surface of the pump door, and the display system 160 has a width greater than the height thereof, and is disposed on the pump door in an overall elongated shape, and the display system 160 may have a width greater than or equal to 70% of the width of the front surface of the pump door 212, the display system 160 may have a height greater than or equal to 60% of the height of the front surface of the pump door 212, or the display system 160 may have an area greater than or equal to 2/3% of the area of the front surface of the pump door 212. When the pump door 212 exhibits a lateral dimension that is greater than a longitudinal dimension, i.e., a width that is greater than a height, the display system 160 has a width that is greater than its height, thereby allowing a larger area of display area to be obtained and allowing the display system 160 to exhibit a rectangular shape with a lateral length. Wherein the pump door 212 is further provided with a physical input key 214 disposed on one side of the display system, for example, the physical input key 214 may be partially or entirely on the right side, upper side, lower side or left side of the display system. The user may enter data or instructions through physical input keys 214. When the display screen of the display system 160 is a touch screen, the user may also input data or instructions through the touch screen. Of course, the physical input keys 214 may be used in emergency situations, and when the touch screen fails and infusion control cannot be performed, the user may perform infusion control through the physical input keys 214 to ensure the safety of the infusion pump.

In some embodiments, the display system 160 includes more than two display screens, at least one of the display screens is formed by laminating a touch layer and a display layer, and the rest of the display screens may be formed by only the display layer. Of course, in order to achieve better touch effect and the touch effect of the user, the display screen included in the display system 160 is formed by laminating a touch layer and a display layer.

Fig. 5 is a block diagram of a hardware configuration of an infusion pump according to an embodiment of the present application. The infusion pump 100 includes components such as a control platform 102, a memory 104, a power supply system 106, an input/output (I/O) system 108, RF circuitry 120, an external port 122, audio circuitry 124, a monitoring circuit 126, protection circuitry 128, detection circuitry 129, power drive circuitry 130, a drop count sensor 132, a bubble sensor 134, a pressure sensor 136, a temperature sensor 138, an optical sensor 139, etc., which communicate via one or more communication buses or signal lines 101. The control platform 102 includes, among other things, a processor 150 and a peripheral interface 152.

The infusion pump 100 may be an infusion pump 20 that performs user-set infusion operations based on user-configured fluids, may controllably infuse configured medical fluids into a patient, or other medical device. The components of the infusion pump 20 may have more or fewer components than shown in fig. 5, or may have a different configuration of components. It should be understood that the infusion pump 100 shown in fig. 5 is merely an example, and that the components of the infusion pump 100 may have more or fewer components than shown in fig. 5, or a different configuration of components. The various components described in fig. 5 may be implemented in hardware, software, or a combination of hardware and software, including one or more signal processing and/or application specific integrated circuits.

The memory 104 may include high-speed random access memory and may also include non-volatile memory, such as one or more magnetic disk storage devices, flash memory devices, or other non-volatile solid-state storage devices. In certain embodiments, the memory 104 may also include memory remote from the one or more processing/controllers 150, such as network-attached memory accessed via the RF circuitry 120 or external port 122 and a communications network (not shown), which may be the internet, one or more intranets, Local Area Networks (LANs), wide area networks (WLANs), storage local area networks (SANs), etc., or a suitable combination thereof. The processor 150 may control access to the memory 104 by other components of the infusion pump 100, other than the peripheral interface 152, to perform detection functions or other functions.

The peripheral interface 152 couples the input and output peripherals of the infusion pump 100 to the processor/controller 150 and the memory 104. For example, peripheral interface 152 may include an input interface and an output interface. The one or more processing/controllers 150 execute various software programs and/or sets of instructions stored in the memory 104 to perform various functions of the infusion pump 100 and process data.

In some embodiments, peripheral interface 152 and processing/controller 150 may be implemented on a single chip. And in one embodiment they may be implemented on a plurality of separate chips. The Processor 150 may be a Central Processing Unit (CPU), other general purpose Processor, a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), an off-the-shelf Programmable Gate Array (FPGA) or other Programmable logic device, discrete Gate or transistor logic, discrete hardware components, etc. A general purpose processor may be a microprocessor or the processor may be any conventional processor or the like.

The RF (radio frequency) circuit 120 receives and transmits electromagnetic waves. The RF circuit 120 converts electrical signals into electromagnetic waves or vice versa and communicates with a communication network and other communication devices via electromagnetic waves. The RF circuitry 120 may include well-known circuitry for performing these functions, including but not limited to an antenna system 156, an RF transceiver, one or more amplifiers, a tuner, one or more oscillators, a digital signal processor, a CODEC chipset, a Subscriber Identity Module (SIM) card, memory, and so forth. The RF circuitry 120 may communicate with networks and other devices via wireless communications, the networks may be the World Wide Web (WWW), an intranet, and/or a wireless network such as a cellular telephone network, a wireless Local Area Network (LAN), and/or a Metropolitan Area Network (MAN). The wireless communication may use any of a variety of communication standards, protocols, and technologies, including, but not limited to, global system for mobile communications (GSM), Enhanced Data GSM Environment (EDGE), Wideband Code Division Multiple Access (WCDMA), Code Division Multiple Access (CDMA), Time Division Multiple Access (TDMA), bluetooth (e.g., IEEE802.15.1), wireless fidelity (WIFI) (e.g., IEEE802.11a, IEEE802.11 b, IEEE802.11g, and/or IEEE802.11n), voice over internet protocol (VoIP), Wi-MAX, protocols for email, instant messaging, and/or Short Message Service (SMS), or any other suitable communication protocol, including communication protocols not yet developed on the filing date herein.

The external port 122 provides a wired communication interface between the infusion pump 100, other devices (e.g., Dock, central station, monitor, etc.), or a user (computer or other communication device). In one embodiment, it may be a communication interface controlled by a CAN bus protocol, a communication interface controlled by a serial communication protocol (e.g., RS485, RS232), or a Universal Serial Bus (USB). The external port 122 is adapted to couple to other devices or users either directly or indirectly via a network (e.g., the internet, LAN, etc.).

The audio circuit 124 and speaker 154 provide an audio interface between the user and the infusion pump 100. The audio circuit 124 receives audio data output through the output interface from the peripheral interface 152, converts the audio data into electrical signals, and transmits the electrical signals to the speaker 154. The speaker 154 converts the electrical signals into sound waves that are perceivable to humans.

The monitoring circuitry 126 may include fault detection circuitry for prompting the status of one or more of the processes/controllers 150.

The protection circuit 128 may include hardware protection devices (e.g., fuses, TVS diodes) for protecting the electrical safety of various components within the infusion pump 100. The processor/controller 150 drives a power device 208 (shown in fig. 6) of the infusion pump 100 through the power driving circuit 130, so that the power device can controllably move under the driving of the processor/controller 150, and during the movement, a control object (such as a pump door 112, a liquid stopping clip, for example) is driven to move through one or more force transmission/conversion devices (such as gears or transmission shafts). The power plant may be an electromagnetic device that converts or transmits electrical energy according to the laws of electromagnetic induction, such as a Permanent Magnet (PM) motor, a reactive (VR) motor, and a Hybrid (HB) motor. In one embodiment, the motor is driven by the processor/controller 150 to move the control object of the infusion pump 100, so that the control object achieves a preset movement state.

In some embodiments, the drop count sensor 132 may be used with a drip chamber of the infusion line 40 to detect the drop flow rate or volume in the drip chamber.

In some embodiments, one or more bubble sensors 134 are used to detect the presence and magnitude of gas within the infusion line 40. The bubble sensor 134 may be an ultrasonic sensor 230 or an infrared sensor, etc.

In one embodiment, the pressure sensor 136 may respond to a pressure value of a measured object (e.g., a wall of the infusion tube 40) and convert the pressure value into an electrical signal for detection and sending to the control platform 102. The pressure sensor 136 may be a resistive strain gauge pressure sensor, a semiconductor strain gauge pressure sensor, a piezoresistive pressure sensor, an inductive pressure sensor, a capacitive pressure sensor, a resonant pressure sensor, a fiber optic pressure sensor, or a capacitive acceleration sensor.

In one embodiment, the infusion pump 100 has a heating device for heating the fluid in a container such as a bag, and the temperature sensor 138 may be used to detect the real-time temperature of the fluid; meanwhile, the temperature value is converted into an electric signal for detection and sent to the control platform 102, and the control platform 102 can display the real-time temperature through the display system 160 and can also perform on/off control on the heating device according to the temperature value.

In some embodiments, an optical sensor 139 may be provided at a predetermined location of the infusion tube 40 for detecting fluid level information within the infusion tube 40 at the predetermined location. At the preset position, if the processor/controller 150 detects the first status information through the optical sensor 139, it indicates that there is liquid in the infusion tube 40 at the preset position, i.e. the liquid level in the infusion tube 40 is not lower than the preset position; when the processor/controller 150 detects the second status information via the optical sensor 139, it indicates that the liquid level in the infusion tube 40 at the predetermined position has fallen below the predetermined position, i.e. gas has passed through the infusion tube 40 at the predetermined position, and the liquid level in the infusion bag has fallen to a position at or below the predetermined position.

An input/output (I/O) system 108 provides an interface between input/output peripherals of the infusion pump 100 and a peripheral interface 152. The input/output peripherals may be a display system 160, position sensors 164, displacement sensors 166, light assemblies 168, and other input/control devices 162. The I/O system 108 may include a display controller 140, a position sensor controller 144, a proximity sensor controller 146, a light controller 148, and one or more input controllers 142. One or more controllers in the I/O system 108 receive/transmit electrical signals from/to input/output peripherals. Where one or more input controllers 142 receive/transmit electrical signals from/to other input/control devices 162. The other input/control devices 162 may include physical buttons (e.g., push buttons, rocker buttons, touch buttons, etc.), slider switches, joysticks, and the like. Other input/control devices 162 may include a physical button for emergency infusion stop, a power button for powering up the infusion pump, and an activation button for the infusion pump to activate the infusion.

In one embodiment, the display system 160 may include a display screen 161 (shown in fig. 6), the display system 160 providing an output interface between the infusion pump 100 and the user that displays electronic files onto the screen via a particular transmission device for reflection to the human eye; the display system 160 may include a cathode ray tube display (CRT), a plasma display PDP or a liquid crystal display LCD, among others. In some embodiments, the display system 160 may include a touch screen that provides an input/output interface between the infusion pump 10 and a user; the touch screen may include a resistive screen, a surface acoustic wave screen, an infrared touch screen, an optical touch screen, a capacitive screen, a nano-film, or the like, which is an inductive display device that may receive an input signal such as a contact. Whether a display screen or a display screen with a touch screen, visual output may be displayed to the user, such as through an output interface in peripheral interface 152. The visual output optionally includes graphics, text, charts, video, and combinations thereof. Some or all of the visual output may correspond to user interface objects, further details of which will be described herein.

The touch screen also accepts user input based on tactile sensation and/or contact. The touch screen forms a touch sensitive surface that receives user input. The touch screen and display controller 140 (along with any associated modules and/or sets of instructions in memory 104) detects contact (and any movement or breaking of the touch) on the touch screen and translates the detected contact into interaction with user interface objects, such as one or more soft keys, displayed on the touch screen. In an embodiment, the point of contact between the touch screen and the user corresponds to one or more fingers of the user. The touch screen may use LCD (liquid crystal display) technology or LPD (light emitting polymer display) technology, but in other embodiments other display technologies may be used. The touch display screen and display controller 140 may detect contact and movement or breaking thereof using any of a number of touch sensitive technologies, including but not limited to capacitive, resistive, infrared, and surface acoustic wave technologies, as well as other proximity sensor arrays, or other technologies for determining one or more points of contact with the touch display screen.

The position sensor 164 may sense the position of the measurand and convert the position to a detectable electrical signal and send the electrical signal to the control platform 102 via the I/O system 108. The position sensor 164 may be a contact sensor that generates a signal by contact pressure of two objects, such as a travel switch, a two-dimensional matrix position sensor; or a proximity sensor that generates a signal by the proximity of two objects to a predetermined distance, such as an electromagnetic type, a photoelectric type, a differential transformer type, an eddy current type, a capacitor type, a reed switch, an ultrasonic type, or a hall type. The object to be measured may include a pump door, an infusion tube, etc. In some embodiments, a Hall position sensor may be used to detect the position of the pump door.

In some embodiments, the control platform 102 may sense whether the infusion tube 40 is installed in the infusion tube slot 205 via the position sensor 164. If the position sensor 164 detects the infusion tube 40 in the detection position of the position sensor 164, the control platform 102 drives the liquid stop clamp to open, so that the liquid stop clamp releases the infusion tube 40. Specifically, a front-end detection device is disposed within the infusion pump 20, wherein the front-end detection device may include one or two or more position sensors 164. For example, when a position sensor is disposed at a position of the infusion tube slot 205 of the infusion pump 20, the processor of the infusion pump 20 determines that the infusion tube 40 is disposed within the infusion pump 20 if it detects that the position sensor at the position transmits a feedback signal; when a position sensor is disposed at a first target position and a position sensor is disposed at a second target position of the infusion tube channel 205, and thus both position sensors detect and transmit feedback information, it is determined that the infusion tube 40 is disposed within the infusion pump 20; the control platform 102 may actuate the clamp to open when the at least one position sensor 164 detects that the wall of the infusion tube 40 is not in contact with the infusion tube channel 205. The infusion tube channel 205 refers to the location in the infusion pump where the infusion tube is installed.

The displacement sensor 166 may be responsive to a change in position of the object being measured relative to the reference position and convert the change in position to a detectable electrical signal and transmit the electrical signal to the control platform 102 via the I/O system 108. The displacement sensor 106 may be inductive, capacitive, ultrasonic, or hall.

The light assembly 168 may include a visual alarm element for alerting the infusion pump 100 of an abnormal condition. The light assemblies 168 are individually responsive to actuation of the processor/controller 150; the light assembly 168 may also be correspondingly engaged with the speaker 154 in response to activation of the processor/controller 150, such as a light that changes color or intensity with the tone, frequency, or duration of the warning sound. The light assembly 168 may include an indicator light or a fluid delivery fault condition warning light for components such as a power source, CPU, etc. The light assembly 168 may also include a visual illumination element for facilitating viewing of the configuration or assembly status of the infusion pump 100 in the event of poor ambient light.

Infusion pump 100 also includes a power system 106 for powering the various components. The power system 106 may include a power management system, one or more power sources (e.g., batteries or Alternating Current (AC)), a charging system, power failure detection circuitry, a power converter or inverter, a power status indicator (e.g., a Light Emitting Diode (LED)), and may include any other components associated with power generation, management, and distribution.

In one embodiment, the software components include an operating system 170, a communication module (or set of instructions) 172, a touch module (or set of instructions) 174, a haptic feedback module (or set of instructions) 176, a motion module (or set of instructions) 178, a location module (or set of instructions) 180, a graphics module (or set of instructions) 182, a text input module (or set of instructions) 190, a device/global internal state (or set of instructions) 192, and one or more applications (sets of instructions) 194.

The operating system 170 (e.g., Darwin, RTXC, LINUX, UNIX, OS, WINDOWS, etc. embedded operating systems) includes various software components and/or drivers for controlling and managing conventional system tasks (e.g., memory management, storage device control, or power management, etc.) as well as facilitating communication between the various software and hardware components.

The communication module 172 facilitates communication with other devices via one or more external ports 122, and it also includes various software components for processing data received by the RF circuitry 120 and/or the external ports 122.

In an embodiment, the touch module 174 may selectively detect contact with the display system 160 or other touch sensitive device (e.g., touch button, touchpad). For example, the touch module 174 in conjunction with the display controller 140 detects contact with the display system 160. The touch module 174 includes various software components for performing various operations associated with detection of contact (which may be by a finger or stylus, etc.) by the display system 160, such as determining whether contact has occurred (e.g., detecting finger press time), determining the strength of contact (e.g., the force or pressure of the contact), determining whether the contact has moved (e.g., detecting one or more finger drag events), or tracking movement on the display screen and determining whether the contact has ceased (e.g., detecting finger lift time or contact break). The operation in which movement of the point of contact is determined may include determining velocity (signal magnitude), velocity (signal magnitude and direction), and/or acceleration (including signal magnitude and/or direction) of the point of contact. These operations may be applied to single point contacts or multiple simultaneous contacts. In one embodiment, the touch module 174 in conjunction with the display controller 140 detects contact by other touch devices.

The touch module 174 may be used to detect gesture input by a user. Different gestures by the user on the touch-sensitive device have different contact patterns (e.g., one or more combinations of locations, times, or intensities at which contacts are detected). For example, detecting a single-finger tap gesture includes detecting a finger-down event and then detecting a finger-up event at the same or a similar location as the finger-down event. For example, detecting a finger swipe gesture on the surface of the touch device includes detecting a finger-down event, then monitoring for one or more finger-dragging events, and then detecting a finger-up event. Similarly, taps, swipes, drags, and other gestures of the stylus are optionally detected by detecting a particular contact pattern of the stylus.

The tactile feedback module 176 includes various software components for generating instructions to generate tactile outputs at one or more locations of the infusion pump 10 using one or more tactile output generators (not shown) in response to user interaction with the infusion pump 10. For example, after detecting contact with the surface of the touch device, the color of the graphics or text of the touch device changes, or sound or vibration is generated.

The location module 180 includes software components for performing various operations related to detecting device location and detecting changes in device location.

Graphics module 182 includes various known software components for rendering or displaying graphics on a display screen of display system 160 or other external device, including components for changing the visual impact (e.g., brightness, transparency, saturation, contrast, or other visual attributes) of the displayed graphics. In embodiments herein, the term "graphics" includes any object that may be displayed to a user, including without limitation text, web pages, icons (e.g., user interface objects for soft keys), digital images, videos, animations, and the like. In some embodiments, the graphics module 182 stores data representing graphics to be used. Each graphic may be assigned a corresponding code. The graphic module 182 receives one or more codes for specifying a graphic to be displayed from an application program or the like, and also receives coordinate data and other graphic attribute data together if necessary, and then generates screen image data to output to the display controller 140.

Text input module 190 provides various software components for entering text in one or more applications. In particular, various infusion parameters may be entered, including drug name, infusion rate, or alarm threshold, etc.

In an embodiment, memory 104 stores device/global internal state 192. Device/global internal state 157 includes one or more of: an active application state indicating which applications (if any) are currently active; display state, which indicates what applications, views, or other information occupy various areas of the display system 160; sensor status, including information obtained from various sensors and other inputs of the device or controlling the infusion pump 10; and position and/or orientation information regarding the position and/or attitude of the device.

In one embodiment, the memory 104 stores at least one application 194, which application 194 may include an infusion mode device 194-1, an occlusion pressure level setting 194-2, a bubble level setting 194-3, a medication setting 194-4, a volume setting 194-5, a brightness setting 194-6, an online setting 195-7, a Dock setting 195-8, or a temperature setting 195-9. The infusion mode device 194-1 may include a combination of preset infusion parameters to meet the requirements of different usage scenarios; wherein the occlusion pressure level setting 194-2 may include an interface providing user input of different occlusion pressure levels by which the occlusion alarm threshold of the infusion pump 10 may be adjusted to suit the needs of different use scenarios. Wherein the bubble level setting 194-3 may include an interface providing user input of different bubble levels by which the bubble alarm threshold of the medical device 10 may be adjusted to suit the needs of different usage scenarios. The medication settings 194-4 may include interfaces for allowing a user to input different names of drugs, acronyms of drugs, and/or colors of drugs, etc. and may be used to set parameters of the medication prior to infusion by inputting corresponding names/acronyms/colors of drugs, etc. to facilitate automatic verification within the infusion pump 100 or verification by a healthcare worker during an infusion procedure. Where volume setting 194-5 provides for the user to adjust the volume of the alarm and/or other audio output as desired. Wherein the brightness setting 194-6 provides the user with the ability to adjust the brightness levels of the screen, warning lights, etc. as desired. The on-line configuration 195-7 provides an input interface for a user to control whether the infusion pump 100 and other devices are on-line, etc. as desired. Wherein Dock settings 195-8 provide a settings interface for a user to adjust operational parameters of a Dock (Dock) connected to the infusion pump 100 as desired. Wherein the temperature device 195-9 provides a user interface for setting the temperature of the fluid in the heated syringe.

In one embodiment, a user may cause a power module of the infusion pump to power, i.e., power up, at least a portion of the electrical components within the infusion pump by touching a power button of the infusion pump. In another embodiment, the user may also power up the infusion pump by wireless control or by directly controlling an external power switch.

In an embodiment, after a power button for powering on the infusion pump is triggered by a user, the infusion pump identifies that the infusion tube is accurately installed in the infusion tube slot through the position sensor, and after each hardware of the infusion pump is determined to be correct through self-checking, the user can send a driving signal to the peristaltic squeezing mechanism through a start button or a start touch button of a display screen or an instruction of other associated equipment (such as a DOCK) by the user, so as to start infusion, wherein in the process of starting infusion, refer to fig. 6, which is a schematic diagram illustrating the peristaltic squeezing mechanism and the infusion tube in the infusion pump. The peristaltic compression mechanism 200 includes a camshaft 202, a set of pump plates 204, and a compression plate 206. A processor in the infusion pump 20 sends instructions such as a rotating speed or a position, and drives a driving mechanism 208 (for example, a motor) to work according to a specified rotating speed and a specified rotating direction through a power driving circuit 130, and the driving mechanism 208 drives a cam shaft 202 connected with the driving mechanism 208 to rotate in the rotating process; during the rotation of the camshaft 202, the pump blade set 204 on the camshaft 202 performs a linear reciprocating motion, that is, the pump blades on the pump blade set 204 sequentially perform a linear reciprocating motion. The pump plate set 204 and the pressing plate 206 cooperate to sequentially and reciprocally press and release the outer wall of the infusion tube 40, so as to drive the liquid in the infusion tube 40 to continuously and directionally flow. A speed reducing mechanism may be further disposed between the driving mechanism 205 and the camshaft 204 to ensure that the rotation speed of the pump plate set 204 is stable and uniform.

Step S102, transmitting ultrasonic waves and collecting corresponding ultrasonic signals.

Referring to fig. 3 and 7, a schematic diagram of an ultrasound sensor assembly of an infusion pump in an embodiment of the present application is shown. The ultrasonic sensor assembly 230 includes an ultrasonic transmitting end (Tx)231 and an ultrasonic receiving end (Rx)233, an ultrasonic driving circuit 149 and an ultrasonic detecting circuit 139, wherein the ultrasonic transmitting end 231 and the ultrasonic receiving end 233 are oppositely disposed. For example, when the ultrasound transducer 230 is disposed in the pump body 210, the ultrasound emitting end 231 is disposed on a first side of the infusion tube channel 205, and the ultrasound receiving end 233 is disposed on a second side of the infusion tube channel 205, the ultrasound emitting end 231 and the ultrasound receiving end 233 can contact the infusion tube 40 when the infusion tube 40 is disposed in the infusion tube channel 205. The processor 150 is connected with the ultrasonic sensor emitting end 231 through the ultrasonic driving circuit 149, the ultrasonic sensor emitting end 231 is controlled to emit ultrasonic waves by sending driving information to the ultrasonic driving circuit 149, the processor 150 is connected with the ultrasonic sensor receiving end 233 through the ultrasonic detection circuit 139, the ultrasonic emitting end 231 emits ultrasonic waves, the ultrasonic waves penetrate through the infusion tube 40, and then the ultrasonic receiving end 233 collects the ultrasonic waves and performs signal processing through the ultrasonic detection circuit 139 to generate corresponding ultrasonic signals. Wherein the ultrasonic detection circuit 139 includes, but is not limited to, performing filtering processes and/or gain adjustments. In an embodiment, the ultrasonic detection circuit 139 may be integrated on the main control circuit board of the processor 150, that is, the processor 150 may directly receive the ultrasonic signal transmitted by the ultrasonic sensor 230 and perform gain adjustment and the like on the ultrasonic signal.

In an embodiment, the ultrasonic sensor 230 may also be other types of sensors, such as a reflective ultrasonic sensor, in which the ultrasonic transmitting end and the ultrasonic receiving end of the ultrasonic sensor 230 are located on the same side of the channel of the infusion tube, when the transmitted ultrasonic wave penetrates through the infusion tube, the ultrasonic wave is reflected at the interface of different materials, and then the ultrasonic receiving end can receive the reflected ultrasonic wave and obtain an ultrasonic signal based on the reflected ultrasonic wave.

In one embodiment, the processor 150 periodically transmits ultrasonic waves and receives corresponding ultrasonic signals through the ultrasonic sensor assembly during the operation of initiating the infusion, and stores the output amplitudes of at least a portion of the ultrasonic signals in the memory 104 for use in subsequent steps.

In one embodiment, the processor 150 may start the ultrasound sensor assembly to periodically emit ultrasound waves and receive corresponding ultrasound signals and use the ultrasound signals for subsequent applications after the infusion pump is powered on and after the infusion operation is initiated, and after the infusion pump is powered on and after the infusion tube is identified as installed. In another embodiment, the processor 150 may also activate the ultrasound transducer assembly to emit ultrasound waves and receive corresponding ultrasound signals after the infusion pump is powered on, but only perform subsequent applications using ultrasound signals after the infusion job is activated or the infusion tube is identified as installed.

Referring also to fig. 11, a graphical representation of the output amplitude of different types of infusion tubes is shown in accordance with an embodiment of the present application. When a manufacturer performs bubble detection on a preset infusion tube (such as an infusion tube with a tube diameter of 1), the ultrasonic sensor 230 generates ultrasonic waves at the emission frequency f0, and the output amplitude of the ultrasonic signal received by the processor 150 is within a normal range (for example, the output amplitude corresponding to the output frequency f0 is located within a saturation and low line and is located at an empirical value), at this time, the processor 150 may also perform normal bubble detection according to the output amplitude of the ultrasonic signal. In some embodiments, the empirical value of the output amplitude is related to the circuit output range of the ultrasonic sensor, and the empirical value of a particular output amplitude may take a value between the saturated output circuit and the too low output voltage. For example, the circuit output range of the ultrasonic sensor is 0.2V-5V, the saturation output voltage is 5V, the too low output voltage is 0.2V, and the empirical value of the output amplitude can be selected to be 2.5V-3V. For example, the circuit output range of the ultrasonic sensor is 0.2V to 3.3V, the saturation output voltage is 3.3V, the too low output voltage is 0.2V, and the empirical value of the output amplitude can be selected to be 2.5V to 3V (target value).

When the infusion tube 10 used by the infusion pump 20 has a thick tube diameter (for example, an infusion tube with a tube diameter of 2), the ultrasonic sensor 230 generates ultrasonic waves at the emitting frequency f0, and at this time, since the driving gain value of the ultrasonic driving circuit or the detection gain value (which may also be referred to as a gain) in the ultrasonic detection circuit 139 is preset or fixed, the intensity of the ultrasonic signal detected by the ultrasonic driving circuit or the ultrasonic detection circuit 139 of the infusion pump 20 may be relatively strong, which causes the signal at the ultrasonic receiving end to be saturated (for example, the output amplitude corresponding to the output frequency f0 exceeds a saturation line), in this case, if there is a bubble passing through the bubble detection ultrasonic sensor, the ultrasonic signal at the ultrasonic receiving end 233 will decrease, but since the ultrasonic receiving end is saturated, the intensity of the ultrasonic signal output by the ultrasonic detection circuit 139 may not change, so that the possibility of bubble omission exists, and clinical accidents occur.

When the infusion tube used by the infusion pump is too thin (such as an infusion tube with a tube diameter of 3), because the driving gain value of the ultrasonic driving circuit or the detection gain value (which may also be a gain value) in the ultrasonic detection circuit 139 is preset or fixed, the output amplitude of the ultrasonic signal may be too small (the output amplitude corresponding to the output frequency f0 is near the too low line and is far from the empirical value line), in this case, the ultrasonic signal transmitted by the ultrasonic receiving end 233 may be filtered out in the processing process of the ultrasonic detection circuit 139, so that the possibility of bubble missing detection or false detection exists, which brings risks and false clinical alarms to clinical application and interferes with the normal use of the infusion pump by medical staff.

And step S104, determining the adjustment information of the ultrasonic driving circuit and/or the ultrasonic detection circuit.

In one embodiment, the processor 150 generates the ultrasonic signals by retrieving one or more historical ultrasonic signals (voltage values) generated within a preset time period in the memory 104; for example, 8 historical ultrasound signals received before the current time can be called; the method can also be understood as calling the ultrasonic signals acquired in one or more acquisition periods before the current moment; it may also be understood as calling up the ultrasonic signal generated within a preset time period (e.g. 20S); the adjusted historical ultrasound signals are averaged to obtain an ultrasound signal baseline (voltage value). The processor may also obtain the baseline (voltage value) of the ultrasound signal by averaging one or more historical ultrasound signals (voltage values) and/or current ultrasound signals generated within a preset time period. The preset time period referred to herein may include a time period before the current time, or may include a time period including the current time, so that the ultrasound signal of the preset time period may include the historical ultrasound signal, or in some cases, the current ultrasound signal.

Comparing the ultrasonic signal baseline with the preset target value, if the difference between the ultrasonic signal baseline and the preset target value exceeds the first threshold range, that is, the absolute value of the difference between the ultrasonic signal baseline and the preset target value is greater than the first threshold, and at this time, the distance between the ultrasonic signal baseline and the preset target value is far, the processor 150 needs to readjust the ultrasonic driving circuit and/or the ultrasonic detection circuit. If the difference between the ultrasonic signal baseline and the preset target value does not exceed the first threshold range, that is, the absolute value of the difference between the ultrasonic signal baseline and the preset target value is smaller than the first threshold, and at this time, the ultrasonic signal baseline is closer to the preset target value, the processor 150 may continue to perform ultrasonic signal acquisition with the current parameters of the ultrasonic drive circuit (the current transmit frequency, and/or the current drive gain value of the drive amplifier circuit) and the ultrasonic detection circuit (the current detection gain value of the detection amplifier circuit), and perform bubble detection with the ultrasonic signal. The preset target value is related to an individual parameter of the ultrasonic sensor, and is generally a preferred value (for example, 2.5V-3V) obtained by an infusion pump manufacturer through detection when the infusion tube is full of water before the infusion pump product leaves the factory. In some embodiments, the preset target value may be selected accordingly based on the type of infusion tube 40 being deployed. For example, the memory 104 stores target values corresponding to different classes of infusion tubes 40, such that when a user selects a class of infusion tube 40 via the interface of the display screen 161, the processor 150 may retrieve from the memory 104 a target value corresponding to the selected class of infusion tube 40.

In some embodiments, when the processor 150 needs to readjust the ultrasonic driving circuit and/or the ultrasonic detection circuit, the adjustment information of the ultrasonic driving circuit may be determined by adjusting the ultrasonic driving circuit in a manner of adjusting the transmission frequency and/or the transmission intensity of the ultrasonic wave.

Fig. 4 is a schematic diagram of an ultrasonic sensor transmitting and receiving ultrasonic signals according to an embodiment of the present invention. The ultrasound emitting end 231 of the ultrasound transducer 230 can generate ultrasound waves with different frequencies based on adjustable emitting parameter values (including but not limited to emitting frequency, emitting intensity, etc.), and the ultrasound receiving end 233 of the ultrasound transducer 230 can receive the ultrasound waves penetrating through the infusion tube 40 and generate corresponding ultrasound signals, wherein the output amplitudes of the ultrasound signals obtained by the ultrasound receiving end 233 can be different after the ultrasound waves with different emitting frequencies penetrate through the infusion tube 40. As shown in fig. 4, the ultrasonic driving circuit 149 may perform frequency modulation on the ultrasonic signal emitted from the ultrasonic emitting end 231 at different emitting frequencies according to instructions of the processor 150 (shown in fig. 5). For example, in the case where the infusion tube 40 is full of water (i.e., the infusion tube does not contain any air bubbles), an ultrasonic wave of frequency f1 is emitted for the first time period t1, and an ultrasonic signal of output amplitude V1 is generated; emitting ultrasonic waves with the frequency of f2 in a second time period t2, and generating an ultrasonic signal with the output amplitude of V2; emitting an ultrasonic wave with a frequency f3 in a third time period t3, and generating an ultrasonic signal with an output amplitude V3, wherein the emitting frequency f1 is less than the emitting frequency f2, and the emitting frequency f2 is less than the emitting frequency f 3; the output magnitude V1 is less than the output magnitude V2, and the output magnitude V2 is less than the output magnitude V3.

In one embodiment, the ultrasonic sensor may not emit ultrasonic waves (or emit ultrasonic waves at a frequency of 0) during the fourth time period t4, and the processor 150 may test the performance of the ultrasonic sensor 230 of the infusion pump 20 according to the ultrasonic signal at the emission frequency of 0 to determine whether the ultrasonic sensor 230 is in a normal operation state. If the transmitting frequency of the ultrasonic sensor 230 is 0 and the output amplitude of the corresponding ultrasonic signal is also 0, the processor 150 may determine that the ultrasonic sensor 230 is in a normal operating state; if the transmitting frequency of the ultrasonic sensor 230 is 0 and the output amplitude of the corresponding ultrasonic signal is not 0, the processor 150 may determine that the ultrasonic sensor 230 is in an abnormal operating state, and at this time, may also output warning information of the abnormality of the ultrasonic sensor.

If the ultrasonic signal baseline is smaller than the preset target value, the transmitting frequency of the ultrasonic driving circuit is required to be increased; if the ultrasonic signal baseline is greater than a preset target value, the transmit frequency of the ultrasonic drive circuit should be reduced. Similarly, if the ultrasonic baseline is smaller than the preset target value, the emission intensity of the ultrasonic drive circuit should be increased; if the ultrasound signal baseline is greater than a preset target value, the transmit intensity of the ultrasound drive circuit should be reduced. Similarly, when the ultrasonic baseline is smaller than the preset target value, the emission intensity and the emission frequency of the ultrasonic drive circuit can be adjusted simultaneously to improve the output amplitude of the ultrasonic signal; when the ultrasonic signal baseline is larger than the preset target value, the emission intensity and the emission frequency of the ultrasonic drive circuit are adjusted simultaneously to reduce the output amplitude of the ultrasonic signal. Therefore, the transmission frequency and/or the transmission intensity (target transmission frequency and/or target transmission intensity) after adjustment can be used as the adjustment information of the ultrasonic drive circuit, and the ultrasonic drive circuit can be adjusted.

In some embodiments, when the processor 150 needs to readjust the ultrasonic driving circuit and/or the ultrasonic detecting circuit, the adjustment information of the ultrasonic driving circuit or the ultrasonic detecting circuit may be determined by adjusting the ultrasonic detecting circuit or the ultrasonic driving circuit to adjust a driving gain value of a driving amplifying circuit in the ultrasonic driving circuit or a detecting gain value of a detecting amplifying circuit in the ultrasonic detecting circuit.

For example, the ultrasonic detection circuit 139 may include a detection amplifier circuit 137 and a filter circuit 135. The filter circuit 135 is configured to filter the ultrasonic signal transmitted by the ultrasonic receiving end 233 of the ultrasonic sensor 230, and obtain the filtered ultrasonic signal. The detection amplifying circuit 137 is configured to perform an amplification process (or gain adjustment) on the filtered ultrasonic signal, so that the processor 150 can obtain the amplified ultrasonic signal. In this embodiment, the ultrasonic detection circuit 139 includes two or more detection amplifying circuits 137, each having a corresponding gain, and thus the ultrasonic detection circuit 139 has detection amplifying circuits with multiple gain values. The processor 150 may also select one, two, or more than two detection amplifying circuits 135 to amplify the ultrasonic signals.

If the ultrasonic signal baseline is smaller than the preset target value, the detection gain value of the detection amplifying circuit is required to be increased; if the ultrasonic signal baseline is greater than a preset target value, the detection gain value of the detection amplification circuit should be decreased. Specifically, the detection amplifying circuit of each ultrasonic detection circuit has a preset adjustable gain range, thresholds at two ends of the detection amplifying circuit are a maximum detection gain value and a minimum detection gain value, if the ultrasonic signal baseline is smaller than a preset target value, a bisection operation can be performed on the current detection gain value and the maximum detection gain value to obtain a new detection gain value (adjustment information), and the processor adjusts the detection amplifying circuit according to the new detection gain value. If the ultrasonic signal baseline is larger than the preset target value, the current detection gain value and the minimum detection gain value can be subjected to dichotomy operation to obtain a target detection gain value (adjustment information), and the processor adjusts the detection amplifying circuit according to the target detection gain value. The target detection gain value can be obtained relatively quickly by utilizing the dichotomy, and the algorithm is simple and quick. Of course, other ways of increasing/decreasing, stepwise increasing/decreasing the current detection gain value by a specific value (e.g., by a preset adjustment value based on the detection gain value of the ultrasonic detection circuit) are equally suitable.

Taking the ultrasonic drive circuit as an example, the ultrasonic drive circuit may include a drive amplification circuit. The drive amplification circuit is used for transmitting the ultrasonic after amplification processing (or gain adjustment) is carried out on the ultrasonic. In this embodiment, the ultrasonic driving circuit includes two or more driving amplifying circuits, each of which has a corresponding gain, and thus the ultrasonic driving circuit has amplifying circuits with a plurality of gain values. The processor can also select one, two or more than two drive amplifying circuits to amplify the ultrasonic waves.

If the ultrasonic signal baseline is smaller than the preset target value, the driving gain value of the driving amplification circuit is required to be increased; if the ultrasonic signal baseline is greater than a preset target value, the drive gain value that drives the amplification circuit should be decreased. Specifically, the driving amplification circuit of each ultrasonic driving circuit has a preset adjustable gain range, the threshold values at the two ends of the driving amplification circuit are a maximum driving gain value and a minimum driving gain value, if the baseline of the ultrasonic signal is smaller than a preset target value, the current driving gain value and the maximum driving gain value can be subjected to dichotomy operation to obtain a new driving gain value (adjustment information), and the processor performs driving adjustment on the driving amplification circuit according to the new driving gain value. If the ultrasonic signal baseline is larger than the preset target value, the current drive gain value and the minimum drive gain value can be subjected to dichotomy operation to obtain a target drive gain value (adjustment information), and the processor performs drive adjustment on the drive amplifying circuit according to the target drive gain value. The target driving gain value can be obtained relatively quickly by utilizing the dichotomy, and the algorithm is simple and quick. Of course, other ways of increasing/decreasing, stepwise increasing/decreasing the current drive gain value by a specific value (e.g., by a preset adjustment value based on the drive gain value of the ultrasonic drive circuit) are equally suitable.

In some embodiments, when the processor 150 needs to readjust the ultrasonic driving circuit and/or the ultrasonic detection circuit, the adjustment information of the ultrasonic driving circuit and/or the ultrasonic detection circuit may be determined by adjusting the ultrasonic driving circuit and the ultrasonic detection circuit simultaneously according to the two embodiments, so as to adjust the transmission frequency, the transmission intensity, and/or the driving gain value of the ultrasonic driving circuit, and adjust the detection gain value of the ultrasonic detection circuit.

In some embodiments, the adjustment information may also adjust the transmission frequency, the transmission intensity, the driving gain value of the ultrasonic driving circuit, and/or the detection gain value of the ultrasonic detection circuit by a preset adjustment value by a fixed value. When the ultrasonic driving circuit and/or the ultrasonic detection circuit need to be adjusted, if the transmitting frequency needs to be adjusted, a preset adjusting value (a fixed value) set based on the transmitting frequency is used as adjusting information, and if the transmitting intensity needs to be adjusted, the preset adjusting value (a fixed value) set based on the transmitting frequency is used as adjusting information; if the amplifying circuit of the ultrasonic driving circuit needs to be adjusted, a preset adjusting value (a fixed value) set by the amplifying circuit based on the ultrasonic driving circuit is used as adjusting information; if the amplifying circuit of the ultrasonic detection circuit needs to be adjusted, a preset adjusting value (a fixed value) based on the amplifying circuit of the ultrasonic detection circuit is used as the adjusting information. Wherein the processor may optionally adjust the at least one adjustment value.

And S106, adjusting the ultrasonic driving circuit and/or the ultrasonic detection circuit according to the adjustment information.

In one embodiment, the processor obtains the adjustment information (target emission frequency, target emission intensity, target driving gain value and/or target detection gain value) from the above embodiments to adjust the ultrasonic driving circuit and/or the ultrasonic detection circuit correspondingly. Specifically, the transmission frequency of the ultrasonic driving circuit, the transmission intensity of the ultrasonic driving circuit, the driving gain value of the ultrasonic driving circuit, and/or the detection gain value of the ultrasonic detection circuit may be adjusted according to the adjustment information.

For example, where the drive amplifier circuit or the sense amplifier circuit includes an adjustable amplification amplifier circuit, the processor may select the amplification corresponding to the target drive gain value or the target sense gain value by sending a signal. The drive amplification circuit of the ultrasonic drive circuit or the detection amplification circuit of the ultrasonic detection circuit may also comprise a plurality of amplifiers with different or the same amplification factor, and the processor may trigger at least one amplifier by sending a signal to obtain an amplification factor adapted to the target drive gain value or the target detection gain value. For example, the processor may send a drive signal to the ultrasound drive circuit to emit ultrasound waves at a target transmit frequency. For example, the processor may send a drive signal to the ultrasound drive circuit to emit ultrasound waves at a target emission intensity.

And S108, determining the bubble state in the infusion tube according to the adjusted ultrasonic signal and the bubble threshold.

The processor compares the acquired ultrasonic signals with a bubble threshold value after the ultrasonic drive circuit and/or the ultrasonic detection circuit are adjusted to determine the state of the bubbles in the infusion tube. Wherein the bubble threshold value can be a memory preset in the infusion pump by factory settings.

In an embodiment, the difference value between the acquired ultrasonic signal and the preset target value after the adjustment by using the adjustment information is within the first threshold range, so that the change of the ultrasonic signal can be recognized, and the accurate measurement of the bubble state of the infusion tube is favorably ensured.

In some embodiments, the bubble threshold may also be adjusted according to an ultrasonic signal (including a historical ultrasonic signal and/or a current ultrasonic signal) in a preset time period, so that the bubble threshold may be adjusted in real time along with the state of the ultrasonic signal, which is beneficial to improving the accuracy of bubble detection. For example, the processor 150 determines an ultrasound signal baseline based on the historical ultrasound signals, and uses the determined ultrasound signal baseline as the bubble threshold, wherein the bubble threshold is linearly related to the ultrasound signal baseline, such as the bubble threshold is a times the ultrasound signal baseline, wherein a is a real number greater than 0. In some embodiments, the bubble threshold and the ultrasound signal baseline may also have a non-linear functional relationship, such as an exponential function, a power function, a logarithmic function, a polynomial function, and other elementary functions, and a complex function of their constituents. For example, the processor 150 may determine the ultrasound signal baseline by calculating an average of the plurality of historical ultrasound signals (i.e., a is 1) and use the determined ultrasound signal baseline as the bubble threshold, or use 90% of the average of the plurality of historical ultrasound signals as the bubble threshold (i.e., a is 0.9). Wherein the plurality of historical ultrasound signals may be continuously obtained by the processor 150 prior to acquiring the currently adjusted ultrasound signal. For example, if the time when the processor 150 acquires the currently adjusted ultrasound signal is tn and the number of the plurality of historical ultrasound signals is 3, the acquisition times corresponding to the plurality of historical ultrasound signals are tn-3, tn-2 and tn-1, respectively. In this embodiment, the processor 150 achieves the purpose of updating the baseline of the ultrasonic signal in time by acquiring a plurality of continuous historical ultrasonic signals before the current adjusted ultrasonic signal is acquired, which is also beneficial to improving the accuracy of subsequent bubble detection. In other embodiments, the bubble threshold may also be a fixed deviation value of the ultrasonic signal baseline, for example, if the ultrasonic signal baseline is B, the bubble threshold may be B + C or B-C, where C is a fixed deviation value.

The ultrasonic wave emitted from the ultrasonic emitting end 231 of the ultrasonic sensor 230 passes through the infusion tube 40, and the ultrasonic wave passes through the interface of two different media, and physical phenomena such as reflection, refraction, transmission and the like occur. Because the acoustic impedance difference between the liquid and the air is large, the ultrasonic waves can be reflected and refracted to a large degree when penetrating through the interface surface of the liquid and the air, and by utilizing the physical phenomenon, the processor 150 receives the ultrasonic signals through the ultrasonic receiving end 233 and obtains the output amplitude (output voltage) of the ultrasonic signals, so that the energy attenuation of the ultrasonic waves is monitored, and whether bubbles exist in the infusion tube or not and the state of the bubbles can be identified according to the energy attenuation degree of the ultrasonic waves.

Referring to fig. 8 to 10, there are shown schematic views of the bubble types in the embodiments of the present application. The types of bubbles may include a first type of bubbles (large bubbles as shown in fig. 8) and a second type of bubbles (small bubbles as shown in fig. 9 or 10). As shown in fig. 8, when a large bubble occurs in the infusion tube 40 and the large bubble is in the detection range of the ultrasonic sensor (or the bubble sensor), a nearly complete air column or a complete air column 41 is formed in the detection range of the ultrasonic sensor, at this time, the ultrasonic wave is greatly attenuated, and the processor 150 can identify the large bubble by monitoring the output amplitude of the ultrasonic signal; the large bubble may be formed by a single bubble or by polymerization of a plurality of bubbles. As shown in fig. 9 and 10, when the

microbubbles

43 and 45 are present in the infusion tube 40 and are within the detection range of the ultrasonic sensor, a part of the gas and a part of the liquid are present in the detection range of the ultrasonic sensor, the bubbles can be freely present in the liquid, and the ultrasonic wave is attenuated less than the large bubbles because of the good penetrability of the ultrasonic wave to the liquid, so that the processor 150 can identify the microbubbles by monitoring the ultrasonic signal.

When a bubble is present in the infusion line 40, the ultrasound signal acquired by the processor 150 will be smaller than the bubble, and therefore, the processor 150 determines the status of the bubble in the infusion line when it detects that the output amplitude of the currently adjusted ultrasound signal is smaller than the baseline ultrasound signal. Referring back to fig. 8-10, since the type of the bubble causes the processor 150 to determine that the output amplitude of the currently adjusted ultrasound signal is different, the processor 150 may also determine the state of the bubble in the infusion tube 40 based on the output amplitude of the currently adjusted ultrasound signal.

As shown in fig. 13, the output amplitude of the ultrasonic signal is at a preset target value 60 when the infusion tube 40 is full of water. The bubble threshold 61 is related to one or more of a brand of an infusion tube, a material of the infusion tube, a diameter of the infusion tube, a type of infusion liquid, an altitude environment, and the like, for example, the bubble threshold in the memory 104 may be provided with a plurality of sets of numerical values, and the processor 150 may call the related bubble threshold for operation according to one or more of the brand of the infusion tube, the material of the infusion tube, the diameter of the infusion tube, and the type of infusion liquid in the altitude environment.

If the ultrasound signal is less than the bubble threshold 61, indicating a relatively large attenuation of the ultrasound waves, it may be assumed that a large bubble (e.g., ultrasound signal 63) is present in the infusion tube, and at this time, the state of the bubble in the infusion tube may be the first type of bubble state. If the output amplitude of the ultrasound signal is greater than the bubble threshold 61, it indicates that the ultrasound wave is only slightly attenuated, and it can be assumed that there are negligible micro-bubbles or even no bubbles (e.g., ultrasound signal 64) in the infusion tube.

In some embodiments, as shown in fig. 13, a second bubble threshold 62 may also be added to determine the ultrasonic signal between the bubble threshold 61 and the second bubble threshold 62 to make a more accurate determination of bubble detection, such as a semi-aqueous state.

In one embodiment, after the processor identifies the presence of a large bubble, it may then follow the following equation:

V＝v×d×t

wherein V is the volume of the large bubbles; v is the flow rate per unit time of the infusion tube, which is generally set by the user according to the order; d is the diameter of the infusion tube; t is the time for the large bubble to pass through the detection range of the bubble sensor.

And step S110, outputting the volume information and/or bubble alarm information of the bubbles according to the bubble state.

After the processor identifies that the large bubble exists in the infusion tube, the processor calculates the volume of the large bubble, compares the volume of the large bubble with a bubble volume threshold preset in the memory, and if the volume of the large bubble is greater than or equal to the bubble volume threshold, the processor controls the infusion pump to be in a liquid stop state, for example, the processor 150 can stop the driving mechanism 208 to stop the pump set 204, and the pump set 204 stops extruding the liquid in the infusion tube 40 to flow in the infusion direction; alternatively, the processor 150 may close the fluid stop clip, so that the fluid stop clip clamps the wall of the infusion tube 40, and the fluid in the infusion tube 40 stops flowing in the infusion direction. The processor may also issue a notification message relating to the large bubble via the peripheral interface, e.g., the processor 150 may control the audio circuit 124 via the peripheral interface 152 to issue an alarm tone to indicate the presence of the large bubble; alternatively, the processor 150 may control the display controller 140 or the light controller 148 through the peripheral device interface 152 to display visual cue information relating to large bubbles on the display system 160 or the light assembly 168; alternatively, the processor 150 may send the cueing information relating to the large bubble to other medical devices (e.g., monitors, Dock) via the external port 122 to display visual cue information about the large bubble on the display system/light assembly of the other medical devices; alternatively, the processor 150 may send prompt information relating to the large bubble to other medical devices (e.g., monitors, Dock) via the external port 122 to sound an alarm tone at the audio circuitry of the other medical devices.

In addition, the processor counts the number of the large bubbles meeting the condition that the volume of the large bubbles is smaller than the bubble volume threshold value, and the statistical result is represented as the accumulated bubble quantity. When the accumulated bubble amount exceeds the preset limit, for example, the processor 150 may control the audio circuit 124 through the peripheral interface 152 to emit an alarm audio to prompt the accumulated bubble amount to exceed the limit; alternatively, the processor 150 may control the display controller 140 or the light controller 148 via the peripheral interface 152 to display a visual cue on the display system 160 or the light assembly 168 that the cumulative bubble amount is exceeded; alternatively, the processor 150 may send a prompt message to other medical devices (e.g., monitor, Dock) via the external port 122 relating to the excess of the accumulated bubble volume to display a visual prompt on the display system/light assembly of the other medical devices relating to the excess of the accumulated bubble volume; alternatively, the processor 150 may send a prompt message via the external port 122 to other medical devices (e.g., monitors, Dock) related to the excess of the accumulated bubble volume to sound an alarm tone at the audio circuitry of the other medical devices.

When the accumulated bubble amount does not exceed the preset limit, the processor controls the infusion pump to be in an infusion state, for example, the processor 150 keeps the driving mechanism to drive the pump sheet set 204 to be in a moving state, and the pump sheet set 204 presses the liquid in the infusion tube 40 to flow in the infusion direction; meanwhile, the processor 150 controls the display controller 140 through the peripheral interface 152 to display the current accumulated bubble amount on the display system 160; alternatively, the processor 150 may send the current accumulated bubble amount to other medical devices (e.g., monitors, Dock) through the external port 122 to display the current accumulated bubble amount on the display system/light assembly of the other medical devices.

When the processor recognizes that the tiny air bubbles exist in the infusion tube, the processor controls the infusion pump to be in the infusion state, for example, the processor 150 keeps the driving mechanism to drive the pump set 204 to be in the moving state, and the pump set 204 presses the liquid in the infusion tube 40 to flow in the infusion direction.

According to the infusion pump bubble detection method, whether bubble detection is possibly influenced due to different pipe diameters of the infusion pipe is determined by comparing the ultrasonic signals obtained in the infusion process with the preset target value, when the ultrasonic signals deviate from the preset target value to a certain degree, the ultrasonic drive circuit and/or the ultrasonic detection circuit are/is adjusted, so that the ultrasonic signals received after adjustment are located near the preset target value, the ultrasonic signals correspond to the pipe diameters of the infusion pipe, self-adaptive control of the ultrasonic signals is achieved, and the problems of bubble omission and false detection caused by different pipe diameters of the infusion pipe are effectively solved.

In some embodiments, as shown in fig. 14, prior to the processor initiating the infusion, the processor performs the steps of:

and S200, controlling an ultrasonic driving circuit to emit ultrasonic waves at an initial emission frequency, an initial emission intensity and an initial driving gain value.

Step S202, receiving an ultrasonic signal which corresponds to the ultrasonic wave and is processed by an ultrasonic detection circuit with an initial detection gain value.

The processor receives the ultrasonic signals which are acquired by the ultrasonic receiving end and attenuated after the ultrasonic waves pass through the infusion tube, and then the signals are amplified, filtered and the like by the initial detection gain value through the ultrasonic detection circuit.

And step S204, if the difference value between the output amplitude of the ultrasonic signal and the preset target value is determined to be in a second threshold range, starting the infusion operation.

The processor then determines whether the ultrasonic signal and the preset target value are in a second threshold range, and if the ultrasonic signal and the preset target value are determined to be in the second threshold range, namely the absolute value of the difference between the ultrasonic signal and the target value is smaller than a second threshold (positive number), the infusion pump is in a state that the infusion can be started, and the infusion can be started at any time according to the instruction of the user and the online starting instruction of the related equipment. Where the second threshold may be the same as the first threshold, and in some embodiments may be somewhat different.

And S206, if the difference value between the output amplitude value number of the ultrasonic signal and the preset target value is determined to be beyond the second threshold range, determining the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit according to at least one of the initial drive gain value, the initial detection gain value, the initial emission frequency and the initial emission intensity.

If the processor determines that the difference between the ultrasonic signal and the preset target value exceeds a second threshold range, namely the absolute value of the difference between the ultrasonic signal and the target value is greater than the second threshold, which indicates that the bubble detection of the infusion pump may be deviated, the processor is required to adjust at least one of the initial driving gain value, the initial detection gain value, the initial emission frequency and the initial emission intensity, so that the ultrasonic driving circuit and/or the ultrasonic control circuit can make the ultrasonic signal after adjustment be within a desired amplitude range, and the change of the ultrasonic signal can be identified.

In some embodiments, the processor may adjust the ultrasonic drive circuit using an average of the initial drive gain value and the maximum drive gain value as the adjustment information, which is suitable for the case where the ultrasonic signal is smaller than the preset target value, and at least one of the adjustment information is determined by bisection, and the algorithm is simple and efficient. In some embodiments, the processor may adjust the ultrasonic drive circuit by using an average value of the initial drive gain value and the minimum drive gain value as at least one of the adjustment information, which is suitable for the case that the ultrasonic signal is larger than the preset target value, and the adjustment information is determined by using the dichotomy, which is efficient and convenient.

In the process of adjusting the initial detection gain value, in some embodiments, the processor may adjust the ultrasonic detection circuit by using an average value of the initial detection gain value and the maximum detection gain value as the adjustment information, which is suitable for the case where the ultrasonic signal is smaller than the preset target value, and at least one of the adjustment information is determined by using the dichotomy, and the algorithm is simple and efficient. In some embodiments, the processor may use an average value of the initial detection gain value and the minimum detection gain value as at least one of the adjustment information to adjust the ultrasonic detection circuit, which is suitable for the case that the ultrasonic signal is larger than the preset target value, and the dichotomy is also used to determine the adjustment information, which is efficient and convenient.

If the output amplitude of the ultrasonic signal is greater than the predetermined target value, indicating that an amplifying circuit having a gain smaller than the initial gain value needs to be selected, the processor 150 may determine the target detection gain value (i.e., the adjustment parameter includes the target detection gain value) based on the minimum detection gain value (e.g., p1) and the current detection gain value (e.g., p0), e.g., determine the target detection gain value is (p1+ p 0)/2. Similarly, if the output amplitude of the ultrasonic signal is smaller than the predetermined target value, indicating that an amplifying circuit with a gain greater than the initial detection gain value needs to be selected, the processor 150 may determine the target detection gain value based on the maximum detection gain value (e.g., p2) and the initial detection gain value, e.g., determine the target detection gain value to be (p2+ p 0)/2.

In an embodiment, taking the adjustment process of the detection gain value as an example, if the absolute value of the difference between the output amplitude of the ultrasonic signal and the preset target value exceeds the second threshold, the processor 150 may determine the target detection gain value as the adjustment information based on a preset interval (a preset adjustment value, such as p 3). For example, if the output amplitude of the ultrasonic signal is greater than the predetermined target value, the processor 150 may determine the target detection gain value based on the predetermined interval and the predetermined detection gain value, such as determining the target detection gain value as (p0-p 3). Similarly, if the output amplitude of the ultrasonic signal is smaller than the predetermined target value, the processor 150 may determine the target detection gain value based on the predetermined interval and the current detection gain value, such as determining the target detection gain value to be (p0+ p 3). In one embodiment, the adjustment to the drive gain value may also adjust the initial drive gain value by a preset adjustment value based on the gain value of the ultrasonic drive circuit, as with the detection gain value, to determine the target gain value.

In the adjusting process of the initial transmitting frequency, as in the adjusting of the initial detection gain value, the target transmitting frequency can be obtained through the dichotomy calculation and is used as at least one of the adjusting information; the initial transmitting frequency may be adjusted and detected step by step at preset frequency intervals to finally determine that the ultrasonic signal closest to the preset target value can be output.

In the adjusting process of the initial emission intensity, as in the adjusting of the initial detection gain value, the target emission intensity may be obtained through the dichotomy calculation as at least one of the adjusting information; the initial emission intensity may also be adjusted and detected step by step at preset intensity intervals (preset adjustment values) to finally determine that the ultrasonic signal closest to the preset target value can be output.

And S208, adjusting the ultrasonic driving circuit and/or the ultrasonic detection circuit according to the adjustment information.

After the processor obtains the adjustment information according to the above mode, the ultrasonic drive circuit and/or the ultrasonic detection circuit are adjusted correspondingly according to the content to be adjusted. Specifically, in the process of adjusting the detection gain value, if the obtained target detection gain value exceeds the maximum detection gain value or is smaller than the minimum detection gain value, the processor determines that the infusion tube is installed incorrectly, and at this time, the processor needs to send out alarm information to prompt the user to perform checking and processing. If the obtained target detection gain value is larger than the minimum detection gain value and smaller than the maximum detection gain value, the processor can adjust the ultrasonic detection circuit according to the target detection gain value.

Before the infusion pump bubble detection method is started for infusion, whether the ultrasonic drive circuit and/or the ultrasonic control circuit can be matched with an infusion tube or not can be detected in advance through ultrasonic waves, problems can be found and solved in advance, the ultrasonic drive circuit and the ultrasonic control circuit can be matched with consumable materials of the infusion tube, ideal ultrasonic signals are obtained, in the process of infusion, the ultrasonic drive circuit and/or the ultrasonic control circuit are adjusted in real time through monitoring the relation between the ultrasonic signals and preset target values, the ultrasonic signals in the infusion process are guaranteed to be in an ideal amplitude range, and bubble omission and false detection are avoided. In addition, the bubble detection device can also be adjusted according to real-time ultrasonic signals and bubble threshold values in the infusion process, so that the bubble detection is more accurate.

In the foregoing embodiments, the descriptions of the respective embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments.

In the embodiments provided in the present application, it should be understood that the disclosed apparatus may be implemented in other manners. For example, the above-described embodiments of the apparatus are merely illustrative, and for example, the division of the units is only one type of division of logical functions, and there may be other divisions when actually implementing, for example, a plurality of units or components may be combined or may be integrated into another system, or some features may be omitted, or not implemented. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection of some interfaces, devices or units, and may be an electric or other form.

The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.

In addition, functional units in the embodiments of the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit.

The foregoing detailed description of the embodiments of the present application has been presented to illustrate the principles and implementations of the present application, and the above description of the embodiments is only provided to help understand the method and the core concept of the present application; meanwhile, for a person skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.

Claims

1. An infusion pump is characterized in that the infusion pump is matched with an infusion tube for use, the infusion pump comprises a peristaltic extrusion mechanism, a processor and an ultrasonic sensor assembly, and the ultrasonic sensor assembly comprises an ultrasonic sensor transmitting end, an ultrasonic sensor receiving end, an ultrasonic driving circuit and an ultrasonic detection circuit; the peristaltic extrusion mechanism comprises a driving mechanism and a pump sheet set; the processor is connected with the transmitting end of the ultrasonic sensor through the ultrasonic driving circuit so as to control the transmitting end of the ultrasonic sensor to transmit ultrasonic waves, the processor is connected with the receiving end of the ultrasonic sensor through the ultrasonic detection circuit so as to receive ultrasonic signals which are acquired by the receiving end of the ultrasonic sensor and are formed by signal processing of the ultrasonic detection circuit, and the driving mechanism drives the pump sheet set to extrude infusion tubes which are arranged along the tube grooves of the infusion tubes of the infusion pump under the control of the processor so as to enable liquid in the infusion tubes to move according to a preset direction;

2. The infusion pump of claim 1, wherein the processor is configured to emit ultrasound waves and acquire corresponding ultrasound signals after the infusion pump is powered on and after an infusion session is initiated or a tubing set is identified.

3. The infusion pump according to claim 1 or 2, wherein the processor is further configured to retrieve the ultrasound signal within a preset time period from the ultrasound signals prior to determining the adjustment information of the ultrasound driving circuit and/or the ultrasound detection circuit, and determine an ultrasound signal baseline according to the ultrasound signals within the preset time period.

4. The infusion pump according to claim 3, wherein said processor is further configured to determine adjustment information of said ultrasound driving circuit and/or ultrasound detection circuit if a difference between said baseline of ultrasound signals and a preset target value is beyond a first threshold range, and adjust a transmission frequency of said ultrasound driving circuit, a transmission intensity of said ultrasound driving circuit, a driving gain value of said ultrasound driving circuit, and/or a detection gain value of said ultrasound detection circuit according to said adjustment information.

5. The infusion pump according to claim 4, wherein a difference between the acquired ultrasound signals after said adjusting and a preset target value is within a first threshold range.

6. The infusion pump according to claim 4 or 5, wherein said adjustment information comprises at least one of a preset adjustment value based on an emission frequency of said ultrasound drive circuit, a preset adjustment value based on an emission intensity of said ultrasound drive circuit, a preset adjustment value based on a drive gain value of said ultrasound drive circuit, and a preset adjustment value based on a detection gain value of said ultrasound detection circuit.

7. The infusion pump according to claim 1 or 4, wherein said processor is further configured to determine adjustment information for said ultrasound drive circuit and/or said ultrasound detection circuit based on at least one of a current transmit frequency of said ultrasound drive circuit, a current transmit intensity of said ultrasound drive circuit, a current drive gain value of said ultrasound drive circuit, and a current detection gain value of said ultrasound detection circuit.

8. The infusion pump according to claim 7, wherein said ultrasound detection circuit comprises a detection amplification circuit, said ultrasound drive circuit comprises a drive amplification circuit, said adjustment information comprises a target detection gain value of said detection amplification circuit and/or a target drive gain value of said drive amplification circuit, said processor is configured to determine a target detection gain value or a target drive gain value based on a current detection gain value of said detection amplification circuit and/or a current drive gain value of said drive amplification circuit, and adjust said detection amplification circuit and/or said drive amplification circuit based on said target detection gain value or target drive gain value.

9. The infusion pump according to claim 7, wherein said adjustment information comprises a target emission frequency and/or a target emission intensity of said ultrasound driving circuit, said processor is configured to correspondingly determine a target emission frequency and/or a target emission intensity according to a current emission frequency and/or a current emission intensity of said ultrasound driving circuit, and adjust said ultrasound driving circuit according to said target emission frequency and/or target emission intensity.

10. The infusion pump according to claim 8, wherein said processor is configured to determine a target drive gain value based on said current drive gain value and a preset minimum drive gain value, or determine said target detection gain value based on said current detection gain value and a preset minimum detection gain value, if said ultrasound signal baseline is greater than said preset target value; or, if the ultrasonic signal baseline is smaller than the preset target value, determining the target driving gain value according to the current driving gain value and a preset maximum driving gain value, or determining the target detection gain value according to the current detection gain value and a preset maximum detection gain value.

11. The infusion pump of claim 3, wherein said processor is further configured to determine said bubble threshold value as a linear function of said ultrasound signal baseline from said ultrasound signal baseline.

12. The infusion pump according to claim 1 or 2, wherein the processor is further configured to control the ultrasound driving circuit to emit ultrasound waves at an initial emission frequency, an initial emission intensity and an initial driving gain value before the infusion is started, receive an ultrasound signal corresponding to the ultrasound waves and processed at an initial detection gain value by the ultrasound detection circuit, and start the infusion operation if it is determined that a difference between an output amplitude of the ultrasound signal and a preset target value is within a second threshold range.

13. The infusion pump according to claim 12, wherein said processor is further configured to determine adjustment information for said ultrasound drive circuit and/or said ultrasound detection circuit if it is determined that the difference between the output amplitude of said ultrasound signal and a preset target value is outside said second threshold range, and to adjust said ultrasound drive circuit and/or said ultrasound detection circuit according to said adjustment information.

14. The infusion pump according to claim 13, wherein said adjustment information comprises at least one of a preset adjustment value based on an emission frequency of said ultrasound drive circuit, a preset adjustment value based on an emission intensity of said ultrasound drive circuit, a preset adjustment value based on a drive gain value of said ultrasound drive circuit, and a preset adjustment value based on a detection gain value of said ultrasound detection circuit; or

The adjustment information is determined according to at least one of the initial driving gain value, initial detection gain value, the initial transmission frequency, and the initial transmission intensity.

15. The infusion pump according to claim 13, wherein said processor is further configured to determine a target driving gain value for a driving amplifier circuit in said ultrasound driving circuit based on said initial driving gain value and a maximum driving gain value, or determine a target detection gain value for a detection amplifier circuit in said ultrasound detection circuit based on an initial detection gain value and a maximum detection gain value, and adjust said driving amplifier circuit or said detection amplifier circuit based on said target driving gain value or said target detection gain value, if it is determined that the output amplitude of said ultrasound signal is less than said preset target value.

16. The infusion pump according to claim 15, wherein said processor is configured to output alarm information regarding an infusion tube if it is determined that said target drive gain value is greater than said maximum drive gain value or less than said minimum drive gain value, or said target detection gain value is greater than said maximum detection gain value or less than said minimum detection gain value; and if the target drive gain value is determined to be smaller than the maximum drive gain value and larger than the minimum drive gain value or the target detection gain value is determined to be smaller than the maximum drive gain value and larger than the minimum drive gain value, adjusting the drive amplification circuit or the detection amplification circuit according to the target drive gain value or the target detection gain value.

17. The bubble detection method for the infusion pump is characterized in that the method is applied to the infusion pump, the infusion pump is matched with an infusion tube for use, the infusion pump comprises a peristaltic extrusion mechanism, a processor and an ultrasonic sensor assembly, and the ultrasonic sensor assembly comprises an ultrasonic sensor transmitting end, an ultrasonic sensor receiving end, an ultrasonic drive circuit and an ultrasonic detection circuit; the peristaltic extrusion mechanism comprises a driving mechanism and a pump sheet set; the processor is connected with the transmitting end of the ultrasonic sensor through the ultrasonic driving circuit so as to control the transmitting end of the ultrasonic sensor to transmit ultrasonic waves, and the processor is connected with the receiving end of the ultrasonic sensor through the ultrasonic detection circuit so as to receive ultrasonic signals which are acquired by the receiving end of the ultrasonic sensor and are formed by signal processing of the ultrasonic detection circuit; the driving mechanism drives the pump sheet set to extrude an infusion tube arranged along an infusion tube groove of the infusion pump under the control of the processor, so that liquid in the infusion tube moves according to a preset direction, and the method comprises the following steps:

powering on the infusion pump;

transmitting ultrasonic waves and collecting corresponding ultrasonic signals;

18. The infusion pump of claim 17, wherein said emitting ultrasound waves and acquiring corresponding ultrasound signals are after power up of said infusion pump and after initiating an infusion session or identifying an infusion tube installation.

19. The infusion pump bubble detection method according to claim 17 or 18, wherein prior to determining the adjustment information for the ultrasound drive circuit and/or the ultrasound detection circuit, further comprising:

calling the ultrasonic signals in a preset time period in the ultrasonic signals;

and determining an ultrasonic signal baseline according to the ultrasonic signal in the preset time period.

20. The infusion pump bubble detection method according to claim 19, wherein said determining adjustment information for the ultrasound drive circuit and/or the ultrasound detection circuit comprises:

if the difference value between the ultrasonic signal baseline and the preset target value exceeds a first threshold value range, determining the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit, and adjusting the emission frequency of the ultrasonic drive circuit, the emission intensity of the ultrasonic drive circuit, the drive gain value of the ultrasonic drive circuit and/or the detection gain value of the ultrasonic detection circuit according to the adjustment information.

21. The infusion pump bubble detection method according to claim 20, wherein a difference between the acquired ultrasound signal after the adjusting and a preset target value is within a first threshold range.

22. The infusion pump bubble detection method according to claim 20 or 21, wherein said determining adjustment information for the ultrasound drive circuit and/or ultrasound detection circuit comprises:

determining adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit based on at least one of a preset adjustment value of a transmission frequency of the ultrasonic drive circuit, a preset adjustment value of a transmission intensity of the ultrasonic drive circuit, a preset adjustment value of a drive gain value of the ultrasonic drive circuit, and a preset adjustment value of a detection gain value of the ultrasonic detection circuit.

23. The infusion pump bubble detection method according to claim 20 or 21, wherein said determining adjustment information for the ultrasound drive circuit and/or the ultrasound detection circuit comprises:

and if the difference value between the ultrasonic signal baseline and a preset target value exceeds a first threshold range, determining the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit according to at least one of the current transmitting frequency of the ultrasonic drive circuit, the current transmitting intensity of the ultrasonic drive circuit, the current drive gain value of the ultrasonic drive circuit and the current detection gain value of the ultrasonic detection circuit.

24. The infusion pump bubble detection method according to claim 23, wherein the ultrasound driving circuit comprises a driving amplification circuit, the ultrasound detection circuit comprises a detection amplification circuit, the adjustment information comprises a target driving gain value of the driving amplification circuit or a target detection gain value of the detection amplification circuit, the determining the adjustment information of the ultrasound driving circuit and/or the ultrasound detection circuit, and the adjusting the ultrasound driving circuit and/or the ultrasound detection circuit according to the adjustment information comprises:

determining a target drive gain value of the drive amplification circuit according to the current drive gain value of the drive amplification circuit, or determining a target detection gain value of the detection amplification circuit according to the current detection gain value of the detection amplification circuit;

and adjusting the driving amplification circuit or the detection amplification circuit according to the target driving gain value or the target detection gain value.

25. The infusion pump bubble detection method according to claim 23 or 24, wherein the adjustment information further comprises a target emission frequency and/or a target emission intensity of the ultrasound drive circuit, the determining adjustment information of the ultrasound drive circuit and/or the ultrasound detection circuit, the adjusting the ultrasound drive circuit and/or the ultrasound detection circuit according to the adjustment information comprises:

correspondingly determining target emission frequency and/or target emission intensity according to the current emission frequency and/or current emission intensity of the ultrasonic driving circuit;

and adjusting the ultrasonic driving circuit according to the target emission frequency and/or the target emission intensity.

26. The infusion pump bubble detection method according to claim 24, wherein determining a target drive gain value for the drive amplifier circuit based on a current drive gain value for the drive amplifier circuit or a target detection gain value for the detection amplifier circuit based on a current detection gain value for the detection amplifier circuit comprises:

if the ultrasonic signal baseline is larger than the preset target value, determining the target driving gain value according to the current driving gain value of the driving amplification circuit and a preset minimum driving gain value, or determining the target detection gain value according to the current monitoring gain value of the detection amplification circuit and a preset minimum detection gain value; alternatively, the first and second electrodes may be,

if the ultrasonic signal baseline is smaller than the preset target value, determining the target drive gain value according to the current drive gain value of the drive amplifying circuit and a preset maximum drive gain value, or determining the target detection gain value according to the current detection gain value of the detection amplifying circuit and a preset maximum detection gain value.

27. The infusion pump bubble detection method according to claim 19, further comprising:

and determining the bubble threshold according to the ultrasonic signal baseline, wherein the bubble threshold and the ultrasonic signal baseline are in a linear function relationship.

28. The infusion pump bubble detection method according to claim 17 or 18, further comprising, prior to initiating an infusion operation:

controlling the ultrasonic drive circuit to emit ultrasonic waves at an initial emission frequency, an initial emission intensity and an initial drive gain;

receiving an ultrasonic signal corresponding to the ultrasonic wave and processed with an initial detection gain value by the ultrasonic detection circuit;

and if the difference value between the ultrasonic signal and the preset target value is determined to be in a second threshold range, starting the infusion operation.

29. The infusion pump bubble detection method according to claim 28, further comprising:

if the difference value between the output amplitude of the ultrasonic signal and a preset target value is determined to exceed the second threshold range, determining the adjustment information of the ultrasonic drive circuit and/or the ultrasonic detection circuit according to at least one of the initial drive gain value, the initial detection gain value, the initial emission frequency and the initial emission intensity;

and adjusting the ultrasonic driving circuit and/or the ultrasonic detection circuit according to the adjustment information.

30. The infusion pump bubble detection method according to claim 28, wherein said determining adjustment information for the ultrasonic drive circuit and/or the ultrasonic detection circuit based on at least one of the initial drive gain value, the initial detection gain value, the initial firing frequency, and the initial firing intensity, and adjusting the ultrasonic drive circuit and/or the ultrasonic detection circuit based on the adjustment information comprises:

if the output amplitude of the ultrasonic signal is larger than the preset target value, determining a target drive gain value of a drive amplifying circuit of the ultrasonic drive circuit according to the initial drive gain value and the minimum drive gain value, or determining a target detection gain value of a detection amplifying circuit in the ultrasonic detection circuit according to the initial detection gain value and the minimum detection gain value, and adjusting the drive amplifying circuit or the detection amplifying circuit according to the target drive gain value or the target detection gain value; or

If the output amplitude of the ultrasonic signal is smaller than the preset target value, determining a target drive gain value of a drive amplifying circuit of the ultrasonic drive circuit according to the initial drive gain value and the maximum drive gain value, or determining a target detection gain value of a detection amplifying circuit in the ultrasonic detection circuit according to the initial detection gain value and the maximum detection gain value, and adjusting the drive amplifying circuit or the detection amplifying circuit according to the target drive gain value or the target detection gain value.

31. The infusion pump bubble detection method according to claim 30, wherein said adjusting the ultrasound detection circuit according to the target drive gain value or target detection gain value comprises:

if the target driving gain value is determined to be larger than the maximum driving gain value or smaller than the minimum driving gain value, outputting alarm information about the infusion tube; if the target drive gain value is determined to be smaller than the maximum drive gain value and larger than the minimum drive gain value, adjusting the ultrasonic detection circuit according to the target drive gain value; or

If the target detection gain value is determined to be larger than the maximum detection gain value or smaller than the minimum detection gain value, outputting alarm information about the infusion tube; and if the target detection gain value is determined to be smaller than the maximum detection gain value and larger than the minimum detection gain value, adjusting the ultrasonic detection circuit according to the target detection gain value.

32. The infusion pump bubble detection method according to claim 19, further comprising:

and determining the bubble threshold according to the ultrasonic signal baseline, wherein the bubble threshold and the ultrasonic signal baseline are in a nonlinear function relationship.