CN113083172B - 一种力学性能提高的核酸水凝胶及其制备方法和用途 - Google Patents

一种力学性能提高的核酸水凝胶及其制备方法和用途 Download PDF

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CN113083172B
CN113083172B CN202110395102.8A CN202110395102A CN113083172B CN 113083172 B CN113083172 B CN 113083172B CN 202110395102 A CN202110395102 A CN 202110395102A CN 113083172 B CN113083172 B CN 113083172B
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nucleic acid
unit
acid strand
strand
scaffold
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CN113083172A (zh
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刘冬生
李宇杰
杨勃
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Tsinghua University
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Tsinghua University
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Priority to PCT/CN2022/086336 priority patent/WO2022218302A1/fr
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0052—Preparation of gels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0052—Preparation of gels
    • B01J13/0065—Preparation of gels containing an organic phase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202110395102.8A 2021-04-13 2021-04-13 一种力学性能提高的核酸水凝胶及其制备方法和用途 Active CN113083172B (zh)

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Application Number Priority Date Filing Date Title
CN202110395102.8A CN113083172B (zh) 2021-04-13 2021-04-13 一种力学性能提高的核酸水凝胶及其制备方法和用途
PCT/CN2022/086336 WO2022218302A1 (fr) 2021-04-13 2022-04-12 Hydrogel d'acide nucléique ayant une propriété mécanique améliorée, son procédé de préparation et son utilisation

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CN202110395102.8A CN113083172B (zh) 2021-04-13 2021-04-13 一种力学性能提高的核酸水凝胶及其制备方法和用途

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CN113083172A CN113083172A (zh) 2021-07-09
CN113083172B true CN113083172B (zh) 2022-04-19

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WO (1) WO2022218302A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113083172B (zh) * 2021-04-13 2022-04-19 清华大学 一种力学性能提高的核酸水凝胶及其制备方法和用途
WO2024027171A1 (fr) * 2022-08-01 2024-02-08 清华大学 Adjuvant comprenant ou consistant en un hydrogel d'acide nucléique et son utilisation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
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JP2002018270A (ja) * 2000-07-03 2002-01-22 Hiroshi Yoshioka 合成ハイドロゲル
US8937171B2 (en) * 2007-01-12 2015-01-20 Japan Science And Technology Agency Nucleic-acid-responsive gel, method for producing same, and use of same
US8715732B2 (en) * 2009-01-05 2014-05-06 Cornell University Nucleic acid hydrogel via rolling circle amplification
WO2014078636A1 (fr) * 2012-11-16 2014-05-22 President And Fellows Of Harvard College Auto-assemblage d'hydrogel d'acides nucléiques
CN107779427B (zh) * 2016-08-26 2021-09-14 清华大学 核酸水凝胶在干细胞诱导分化中的用途
CN107773527B (zh) * 2016-08-26 2021-06-25 清华大学 以核酸水凝胶作为载体的疫苗组合物
CN107569448B (zh) * 2017-09-06 2020-08-25 青岛大学 一种自组装dna水凝胶的制备方法及其应用
CN109554331B (zh) * 2017-09-27 2022-09-27 清华大学 L-核酸水凝胶
CN110180026B (zh) * 2019-06-27 2021-02-09 清华-伯克利深圳学院筹备办公室 一种生物支架及其制备方法和应用
CN112522373B (zh) * 2021-02-03 2021-11-26 中国农业大学 一种蜘蛛网状自组装功能核酸水凝胶的制备方法
CN113083172B (zh) * 2021-04-13 2022-04-19 清华大学 一种力学性能提高的核酸水凝胶及其制备方法和用途

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WO2022218302A9 (fr) 2022-12-08
WO2022218302A1 (fr) 2022-10-20
CN113083172A (zh) 2021-07-09

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