CN113083100A - Antigen emulsifying device and working method thereof - Google Patents

Antigen emulsifying device and working method thereof Download PDF

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Publication number
CN113083100A
CN113083100A CN202110361534.7A CN202110361534A CN113083100A CN 113083100 A CN113083100 A CN 113083100A CN 202110361534 A CN202110361534 A CN 202110361534A CN 113083100 A CN113083100 A CN 113083100A
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China
Prior art keywords
layer
partition plate
crankshaft
gear
fixedly connected
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CN202110361534.7A
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Chinese (zh)
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CN113083100B (en
Inventor
彭永毅
王硕硕
强茂
孙谧
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Qingdao Ruisikeer Biotechnology Co ltd
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Qingdao Ruisikeer Biotechnology Co ltd
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Publication of CN113083100A publication Critical patent/CN113083100A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/80Mixers with rotating receptacles rotating about a substantially vertical axis
    • B01F29/83Mixers with rotating receptacles rotating about a substantially vertical axis with rotary paddles or arms, e.g. movable out of the receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/717Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/718Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
    • B01F35/71801Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system using a syphon to create a suction of a component
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80Forming a predetermined ratio of the substances to be mixed
    • B01F35/88Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
    • B01F35/882Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise using measuring chambers, e.g. volumetric pumps, for feeding the substances
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)

Abstract

The invention provides an antigen emulsifying device and a working method thereof, belonging to the technical field of emulsifying equipment, wherein the antigen emulsifying device comprises a rack, an oscillating device, an emulsifying device and a metering device, wherein the rack comprises a first layer of partition plate, a second layer of partition plate, a third layer of partition plate and support plates positioned at two sides of the first layer of partition plate, the second layer of partition plate and the third layer of partition plate which are sequentially distributed in an array manner from top to bottom, and the top of the second layer of partition plate is provided with a movable hole; the oscillating device comprises a driving piece, a reciprocating piece and a rotating piece, wherein the driving piece is used for driving the reciprocating piece to reciprocate transversely along the length direction, so that the rotating piece continuously drives the stirring kettle to rotate, and raw materials are fully fused; when the raw materials are accumulated to submerge the highest point of the discharge channel, the raw materials are sucked into the stirring kettle from the discharge channel through the siphon principle, and the raw material proportion can be ensured to be more accurate.

Description

Antigen emulsifying device and working method thereof
Technical Field
The invention belongs to the technical field of emulsification equipment, and particularly relates to an antigen emulsification device and a working method thereof.
Background
In the process of preparing the antibody, before the animal is immunized, the water-soluble antigen and the oily adjuvant are required to be fully and uniformly mixed to form an antigen emulsion, so that the immunization can be carried out, and the process is called emulsification.
The immunological detection technology is widely applied to the aspects of monitoring harmful substances in food and agricultural products, diagnosing human and animal diseases and the like, and provides powerful technical support for guaranteeing the consumption safety and the body health of people in China. Wherein: the first step of antigen immunization in antibody preparation is a key step in immunological detection techniques. Before antigen immunization, the antigen is generally emulsified with an immunological adjuvant such as Freund's adjuvant to prepare a "water-in-oil" emulsion, and then injected for immunization. The immune adjuvant has the following main effects: (1) the release of the antigen is delayed, the antigen is protected from being hydrolyzed, the retention time of the antigen in a body is prolonged, frequent injection is avoided, and the generation of high-affinity antibodies is facilitated; (2) activating macrophages and promoting interaction of macrophages with T and B cells, thereby having a specific boosting stimulation effect on lymphocytes; (3) after the adjuvant adsorbs the antigen, the surface area of the antigen is increased, so that the antigen is easily phagocytized by macrophages; (4) can stimulate phagocyte to process antigen; (5) can stimulate malignant division of sensitized lymphocytes and production of antibodies by plasma cells; (6) can improve the body dropping of the primary and secondary immune response of the body; (7) changes the production type of the antibody and generates delayed type allergy, and enhances the production.
The existing oscillator for emulsification has low power, so that the water-soluble antigen and the oily adjuvant cannot be fully stirred, the emulsification effect is low easily, the emulsification time is too long, the production efficiency is reduced, the economic cost is increased, and the manpower is wasted by operating the oscillator by a specially-assigned person.
Disclosure of Invention
The embodiment of the invention provides an antigen emulsifying device and a working method thereof, and aims to solve the problems that the existing emulsifying oscillator is low in power, low in emulsifying effect and long in emulsifying time, and manpower is wasted due to the fact that a specially-assigned person must operate the oscillator.
In view of the above problems, the technical solution proposed by the present invention is:
the present invention provides an antigen emulsifying device, comprising:
the rack comprises a first layer of partition plates, a second layer of partition plates, a third layer of partition plates and support plates positioned on two sides of the first layer of partition plates, the second layer of partition plates and the third layer of partition plates, wherein the first layer of partition plates, the second layer of partition plates and the third layer of partition plates are sequentially distributed in an array manner from top to bottom;
the vibrating device comprises a driving piece, a reciprocating piece and a rotating piece, wherein the driving piece is used for driving the reciprocating piece to reciprocate and transversely move along the length direction, so that the rotating piece continuously drives the stirring kettle to rotate, and raw materials are fully fused;
the driving piece comprises a first driving motor, a driving shaft, a driving bevel gear, a driven bevel gear and a rotating shaft, the first driving motor is fixedly installed at the bottom of the third layer of partition plate, the output end of the first driving motor is fixedly connected with the driving shaft, one end of the driving shaft is sleeved with the driving bevel gear, the driving bevel gear is in meshing connection with the driven bevel gear, the rotating shaft is fixedly connected with the inner shaft of the driven bevel gear, and one end of the rotating shaft penetrates through the third layer of partition plate and extends to the position above the third layer of partition plate;
the reciprocating element is positioned above the third layer of partition plate and comprises a hollow wheel, a moving rod, a support sleeve and an eccentric wheel, the moving rod is integrally formed on two sides of the hollow wheel, the support sleeve is arranged on the surface of the moving rod and fixedly connected above the third layer of partition plate, the eccentric wheel is arranged inside the hollow wheel, and one end of the rotating shaft, which is positioned above the third layer of partition plate, is fixedly connected with an inner shaft of the eccentric wheel;
the rotating part comprises a first connecting rod, a second connecting rod, a bearing seat, a first crankshaft and a first rotary table, one end of the first connecting rod is fixedly connected with one end of the moving rod, the other end of the first connecting rod penetrates through the movable hole and extends to the position above the second layer of partition plate, one end of the first connecting rod, which is positioned above the second layer of partition plate, is connected with the second connecting rod, the other end of the second connecting rod is rotatably connected with the first crankshaft, one end of the first crankshaft is rotatably connected with the bearing seat, the other end of the first crankshaft penetrates through the first layer of partition plate and extends to the position above the first layer of partition plate, and one end of the first crankshaft, which is positioned above the first layer of partition plate, is fixedly connected with the first;
an emulsifying device, the emulsifying device comprises a stirring kettle, a second driving motor, a first gear, a second gear and a gear ring, the stirring kettle is fixedly connected with the top of the first rotary table, the top of the stirring kettle is fixedly provided with the second driving motor, the output end of the second driving motor is fixedly connected with a second crankshaft, the second crankshaft is positioned in the stirring kettle, one end of the second crankshaft is fixedly connected with a connecting sleeve, the first gear sleeve is arranged on the surface of the first crankshaft, the second gear is in meshed connection with the first gear, the inner shaft of the second gear is fixedly connected with a transmission rod, the transmission rod is rotatably connected with the connecting sleeve, one end of the transmission rod is fixedly connected with a mounting plate, the bottom of the mounting plate is provided with a stirring paddle, and the gear ring is fixedly connected with the inner wall of the stirring kettle, the second gear is in meshed connection with the gear ring.
The metering device comprises a metering piece for controlling the material feeding amount, a transmission piece for adjusting the material feeding amount proportion and a material conveying piece for controlling the material conveying speed.
As a preferable technical scheme of the invention, a circular slideway is arranged at the top of the first layer of partition plate, and a pulley is arranged at the bottom of the first turntable and is in sliding connection with the slideway.
As a preferable technical scheme of the present invention, the number of the stirring paddles is at least one, the mounting plate is circular, and the stirring paddles are distributed around the bottom of the mounting plate.
As a preferable technical scheme of the invention, the bottom of the stirring kettle is communicated with a discharge pipe, and one end of the discharge pipe is provided with a first electromagnetic valve.
As a preferable technical scheme, the metering piece comprises a second rotary disc, mounting holes, a meter and a concentric shaft, the second rotary disc is embedded into the top of the stirring kettle and is rotationally connected with the stirring kettle, a plurality of mounting holes are distributed around the top of the second rotary disc, the meter is arranged in each mounting hole, and the axis of the second rotary disc is fixedly connected with the concentric shaft.
As a preferred technical scheme of the present invention, the meter includes a metering cylinder, a flow-assisting channel, a feeding channel and a discharging channel, the feeding channel, the flow-assisting channel and the discharging channel for accommodating raw material flow are arranged inside the metering cylinder, the feeding channel, the flow-assisting channel and the discharging channel are sequentially communicated to form an inverted U-shaped discharge channel, and the discharging channel extends to the inside of the stirring tank.
As a preferable technical solution of the present invention, the horizontal positions of the highest points of the discharge channels of the plurality of meters are not uniform.
As a preferable technical scheme of the invention, the transmission member comprises a third driving motor, a synchronizing shaft, a first rotating wheel, a second rotating wheel and a transmission belt, the third driving motor is fixedly mounted at the rear side of the stirring kettle, the output end of the third driving motor is fixedly connected with the synchronizing shaft, one end of the synchronizing shaft is sleeved with the first rotating wheel, the second rotating wheel is sleeved at one end of the concentric shaft, and the first rotating wheel and the second rotating wheel are rotatably connected through the transmission belt.
As a preferable technical scheme, the material conveying piece comprises a conveying pipe, supporting legs, a second electromagnetic valve and a flange plate, the supporting legs are arranged on the surface of the conveying pipe and fixedly connected to the top of the stirring kettle, the second electromagnetic valve is mounted on the conveying pipe, and one end of the conveying pipe is connected with the flange plate.
In another aspect, the present invention provides a method of operating an antigen emulsifying device, comprising the steps of:
s1, metering feed: the conveying pipe is communicated with an external conveying pipe through a flange pipe, a second electromagnetic valve is started to enable the raw materials to enter the metering cylinder, and when the raw materials are accumulated to submerge the highest point of the discharge channel, the raw materials are sucked into the stirring kettle from the discharge channel through a siphon principle;
s2, oscillation fusion: after raw materials enter the stirring kettle, a first driving motor is started to be electrified to drive a driving shaft and a driving bevel gear to rotate, so that a driven bevel gear can drive a rotating shaft and an eccentric wheel to rotate, the eccentric wheel can drive a hollow wheel and a moving rod to transversely reciprocate along the length direction, the first connecting rod transversely reciprocates in a movable hole, the second connecting rod transversely reciprocates along with the first connecting rod to push a second crankshaft, the second crankshaft drives a first rotating disc to rotate, and the stirring kettle is driven to rotate to enable the materials to be oscillated and fused;
s3, fusion and stirring: and a second driving motor is started to be electrified to drive a second crankshaft to rotate, so that the stirring paddle rotates around the inner wall of the stirring kettle, and meanwhile, the second crankshaft drives a second gear to rotate around the gear ring, so that the second gear drives the stirring paddle to perform autorotation stirring to obtain a mixed solution.
Compared with the prior art, the invention has the beneficial effects that:
(1) through the oscillating device who sets up, it is rotatory to open first driving motor circular telegram drive shaft and drive bevel gear, can make driven bevel gear drive pivot and eccentric wheel rotatory, and the eccentric wheel can drive hollow wheel and carriage release lever along length direction horizontal reciprocating motion, makes first connecting rod horizontal reciprocating motion in the movable hole, and the second connecting rod is followed first connecting rod horizontal reciprocating motion and is promoted the second bent axle, causes the second bent axle to drive first carousel rotation to drive stirred tank and rotate and make the material oscillation fuse.
(2) Through the emulsification device who sets up, it is rotatory to open second driving motor circular telegram drive second bent axle for the stirring rake is rotatory around stirred tank's inner wall, and the second bent axle drives the second gear simultaneously and is rotatory around the ring gear, can make the second gear drive stirring rake carry out the rotation stirring, thereby makes the mixed solution obtain intensive mixing.
(3) Through the metering device who sets up, open the second solenoid valve and make the raw materials get into a metering section of thick bamboo, treat that the raw materials accumulates when flooding discharge passage peak, through the siphon principle, the raw materials is from discharge passage is inhaled in the stirred tank, can guarantee the more accurate of raw materials proportion.
The foregoing description is only an overview of the technical solutions of the present invention, and the embodiments of the present invention are described below in order to make the technical means of the present invention more clearly understood and to make the above and other objects, features, and advantages of the present invention more clearly understandable.
Drawings
FIG. 1 is a schematic structural diagram of an antigen emulsifying device disclosed in the present invention;
FIG. 2 is a schematic view of a stirred tank structure of the antigen emulsifying device disclosed by the invention;
FIG. 3 is a top view of the reciprocating member of the disclosed antigen emulsifying device;
FIG. 4 is a top view of a stirred tank of the antigen emulsifying device disclosed by the invention;
FIG. 5 is a cross-sectional view of a meter of the antigen emulsifying device disclosed in the present invention;
FIG. 6 is a perspective view of a first crankshaft of the disclosed antigen emulsifying device;
FIG. 7 is a top view of a second layer of baffles of the disclosed antigen emulsifying device;
FIG. 8 is a flow chart of the operation of the antigen emulsifying apparatus according to the present invention.
Description of reference numerals: 100-oscillating device, 110-driving piece, 111-first driving motor, 112-driving shaft, 113-driving bevel gear, 114-driven bevel gear, 115-rotating shaft, 120-reciprocating piece, 121-hollow wheel, 122-moving rod, 123-supporting sleeve, 124-eccentric wheel, 130-rotating piece, 131-first connecting rod, 132-second connecting rod, 133-bearing seat, 134-first crankshaft, 135-first turntable, 1351-pulley, 1352-slideway, 200-emulsifying device, 210-stirring kettle, 220-second driving motor, 221-second crankshaft, 222-connecting sleeve, 230-first gear, 240-second gear, 241-driving rod, 242-mounting plate, 243-stirring paddle, 250-gear ring, 260-discharge pipe, 261-first electromagnetic valve, 300-metering device, 310-metering part, 311-second rotary disc, 312-mounting hole, 313-metering part, 3131-metering cylinder, 3132-flow-assisting channel, 3133-feeding channel, 3134-discharging channel, 314-concentric shaft, 320-transmission part, 321-third driving motor, 322-synchronous shaft, 323-first rotating wheel, 324-second rotating wheel, 325-driving belt, 330-material conveying part, 331-conveying pipe, 332-supporting foot, 333-second electromagnetic valve, 334-flange plate, 400-frame and 410-movable hole.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Example one
Referring to the attached drawings 1-7, the invention provides a technical scheme: the antigen emulsifying device comprises a frame 400, an oscillating device 100, an emulsifying device 200 and a metering device 300;
referring to fig. 1, the frame 400 includes a first layer of partition boards, a second layer of partition boards, a third layer of partition boards, and support boards located on two sides of the first layer of partition boards, the second layer of partition boards, and the third layer of partition boards, which are sequentially distributed in an array from top to bottom, and a movable hole 410 is formed in the top of the second layer of partition boards.
Referring to fig. 1, 3, and 6 to 7, the oscillating device 100 includes a driving member 110, a reciprocating member 120, and a rotating member 130, wherein the driving member 110 is used to drive the reciprocating member 120 to reciprocate along the length direction and move transversely, so that the rotating member 130 continuously drives the stirring tank 210 to rotate, thereby achieving the purpose of fully fusing the raw materials.
The driving member 110 includes a first driving motor 111, a driving shaft 112, a driving bevel gear 113, a driven bevel gear 114 and a rotating shaft 115, the first driving motor 111 is fixedly installed at the bottom of the third-layer partition plate, the output end of the first driving motor 111 is fixedly connected with the driving shaft 112, one end of the driving shaft 112 is sleeved with the driving bevel gear 113, the driving bevel gear 113 is in meshing connection with the driven bevel gear 114, the inner shaft of the driven bevel gear 114 is fixedly connected with the rotating shaft 115, and one end of the rotating shaft 115 penetrates through the third-layer partition plate and extends to the upper side of the third-layer partition plate; by turning on the first driving motor 111 to drive the driving shaft 112 and the driving bevel gear 113 to rotate, the driven bevel gear 114 drives the rotating shaft 115 to cause the reciprocating member 120 to reciprocate transversely in the length direction.
The reciprocating element 120 is positioned above the third layer of partition plates, the reciprocating element 120 comprises a hollow wheel 121, a moving rod 122, a supporting sleeve 123 and an eccentric wheel 124, the moving rod 122 is integrally formed on two sides of the hollow wheel 121, the supporting sleeve 123 is arranged on the surface of the moving rod 122, the supporting sleeve 123 is fixedly connected above the third layer of partition plates, the eccentric wheel 124 is arranged inside the hollow wheel 121, and one end of the rotating shaft 115, which is positioned above the third layer of partition plates, is fixedly connected with the inner shaft of the eccentric wheel 124; the eccentric wheel 124 can drive the hollow wheel 121 and the movable rod 122 to reciprocate transversely along the length direction by the power provided by the driving member 110.
The rotating member 130 comprises a first connecting rod 131, a second connecting rod 132, a bearing seat 133, a first crankshaft 134 and a first rotary disc 135, one end of the first connecting rod 131 is fixedly connected with one end of the moving rod 122, the other end of the first connecting rod passes through the movable hole 410 and extends to the upper side of the second layer of partition plate, one end of the first connecting rod 131, which is positioned above the second layer of partition plate, is connected with the second connecting rod 132, the other end of the second connecting rod 132 is rotatably connected with the first crankshaft 134, one end of the first crankshaft 134 is rotatably connected with the bearing seat 133, the other end of the first crankshaft penetrates through the first layer of partition plate and extends to the upper side of the first layer of partition plate, and one end of the first crankshaft 134; through the transmission of the reciprocating motion member 120, the first connecting rod 131 is transversely reciprocated in the movable hole 410, and the second connecting rod 132 pushes the second crankshaft 221 along with the transverse reciprocation of the first connecting rod 131, so that the second crankshaft 221 drives the first rotary disc 135 to rotate and drives the stirring kettle 210 to rotate to make the materials oscillate and fuse.
Referring to fig. 1-2, the emulsifying device 200 includes a stirring tank 210, a second driving motor 220, a first gear 230, a second gear 240 and a gear ring 250, the stirring tank 210 is fixedly connected to the top of the first rotary plate 135, the second driving motor 220 is fixedly installed on the top of the stirring tank 210, the output end of the second driving motor 220 is fixedly connected to a second crankshaft 221, the second crankshaft 221 is located inside the stirred tank 210, one end of the second crankshaft 221 is fixedly connected with a connecting sleeve 222, the first gear 230 is sleeved on the surface of the first crankshaft 134, the second gear 240 is in meshed connection with the first gear 230, an inner shaft of the second gear 240 is fixedly connected with a transmission rod 241, the transmission rod 241 is rotatably connected with the connecting sleeve 222, one end of the transmission rod 241 is fixedly connected with a mounting plate 242, a stirring paddle 243 is mounted at the bottom of the mounting plate 242, the gear ring 250 is fixedly connected to the inner wall of the stirred tank 210, and the second gear 240 is in meshed connection with the gear ring 250.
In this embodiment, the second driving motor 220 is turned on to drive the second crankshaft 221 to rotate, so that the stirring paddle 243 rotates around the inner wall of the stirring tank 210, and at the same time, the second crankshaft 221 drives the second gear 240 to rotate around the gear ring 250, so that the second gear 240 drives the stirring paddle 243 to perform rotation stirring.
Referring to fig. 1 and 3, the metering device 300 includes a metering member 310 for controlling the amount of material fed, a transmission member 320 for adjusting the proportion of the amount of material fed, and a material conveying member 330 for controlling the speed of material conveyance.
In this embodiment, the number of the metering devices 300 is at least two, so that the metering of various materials with different proportions can be ensured, and the metering work is more efficient.
Referring to fig. 1-2 and 5-6, the metering member 310 includes a second turntable 311, mounting holes 312, a meter 313 and a concentric shaft 314, the second turntable 311 is embedded in the top of the stirring kettle 210, the second turntable 311 is rotatably connected with the stirring kettle 210, the plurality of mounting holes 312 are distributed around the top of the second turntable 311, the meter 313 is disposed inside each of the plurality of mounting holes 312, and the concentric shaft 314 is fixedly connected to the axis of the second turntable 311.
Counter 313 comprises a metering cylinder 3131, a flow-assisting channel 3132, a feeding channel 3133 and a discharging channel 3134, wherein the interior of metering cylinder 3131 is provided with a feeding channel 3133, a flow-assisting channel 3132 and a discharging channel 3134 for accommodating raw material flow, feeding channel 3133, flow-assisting channel 3132 and discharging channel 3134 are sequentially communicated to form an inverted U-shaped discharging channel, and discharging channel 3134 extends to the interior of stirring kettle 210; when the raw material enters the metering cylinder 3131 and accumulates to the highest point of the submerged discharge channel, the raw material is sucked into the stirred tank 210 from the discharge channel by the siphon principle.
The transmission member 320 comprises a third driving motor 321, a synchronizing shaft 322, a first rotating wheel 323, a second rotating wheel 324 and a transmission belt 325, the third driving motor 321 is fixedly installed at the rear side of the stirring kettle 210, the output end of the third driving motor 321 is fixedly connected with the synchronizing shaft 322, one end of the synchronizing shaft 322 is sleeved with the first rotating wheel 323, the second rotating wheel 324 is sleeved at one end of the concentric shaft 314, and the first rotating wheel 323 and the second rotating wheel 324 are rotatably connected through the transmission belt 325; in actual production, the mixed solution of each batch of products has different proportions, so that during the metering process, the third driving motor 321 is started to be powered on to drive the synchronizing shaft 322 to drive the first rotating wheel 323 to rotate, and the second rotating wheel 324 drives the concentric shaft 314 and the second rotating wheel 311 to rotate through the transmission action of the transmission belt 325, so as to rotate the appropriate meter 313 according to the proportion of the mixed solution for metering.
In the present embodiment, the horizontal positions of the highest points of the discharge channels of the plurality of meters 313 are all not uniform; so as to be convenient for metering the raw materials according to the proportion control of the mixed solution.
The material conveying part 330 comprises a conveying pipe 331, a supporting leg 332, a second electromagnetic valve 333 and a flange plate 334, wherein the supporting leg 332 is arranged on the surface of the conveying pipe 331, the supporting leg 332 is fixedly connected to the top of the stirring kettle 210, the second electromagnetic valve 333 is mounted on the conveying pipe 331, and one end of the conveying pipe 331 is connected with the flange plate 334; the delivery pipe 331 is communicated with an external delivery pipe through a flange pipe, meanwhile, in the stirring process of the emulsifying device 200, the second electromagnetic valve 333 can control the feeding amount of the raw material entering the metering cylinder 3131, and after the mixed solution in the stirring kettle 210 is melted and discharged, the raw material of the metering cylinder 3131 just reaches the highest point of the discharge channel, so that the raw material can enter the stirring kettle 210 to perform the next round of emulsification.
In the embodiment of the invention, a circular slideway 1352 is arranged at the top of the first layer of partition board, a pulley 1351 is arranged at the bottom of the first rotary disc 135, and the pulley 1351 is slidably connected with the slideway 1352; the pulley 1351 provides support for the first turntable 135 as the first turntable 135 rotates, and the pulley 1351 is fitted to slide in the circular slideway 1352, thereby avoiding the generation of friction.
In the embodiment of the present invention, the number of the stirring paddles 243 is at least one, the mounting plate 242 has a circular shape, and the stirring paddles 243 are distributed around the bottom of the mounting plate 242; the plurality of paddles 243 can ensure that the mixed solution is more sufficiently mixed.
In the embodiment of the present invention, the bottom of the stirring kettle 210 is communicated with a discharge pipe 260, and one end of the discharge pipe 260 is provided with a first electromagnetic valve 261; after the mixed solution is emulsified, the first electromagnetic valve 261 is opened to be electrified, and the discharge pipe 260 is communicated with an external pipeline to facilitate the discharge of the mixed solution.
Example two
Referring to fig. 8, an embodiment of the present invention further provides a working method of an antigen emulsifying apparatus, including the following steps:
s1, metering feed: the delivery pipe 331 is communicated with an external delivery pipe through a flange pipe, the second electromagnetic valve 333 is opened to enable the raw materials to enter the metering cylinder 3131, and when the raw materials are accumulated to submerge the highest point of the discharge channel, the raw materials are sucked into the stirring kettle 210 from the discharge channel through the siphon principle;
s2, oscillation fusion: after the raw materials enter the stirring kettle 210, starting the first driving motor 111 to electrify and drive the driving shaft 112 and the driving bevel gear 113 to rotate, so that the driven bevel gear 114 drives the rotating shaft 115 and the eccentric wheel 124 to rotate, the eccentric wheel 124 can drive the hollow wheel 121 and the moving rod 122 to transversely reciprocate along the length direction, so that the first connecting rod 131 transversely reciprocates in the movable hole 410, the second connecting rod 132 transversely reciprocates along with the first connecting rod 131 to push the second crankshaft 221, so that the second crankshaft 221 drives the first rotating disc 135 to rotate, and drives the stirring kettle 210 to rotate so as to enable the materials to oscillate and fuse;
s3, fusion and stirring: the second driving motor 220 is started to be powered on to drive the second crankshaft 221 to rotate, so that the stirring paddle 243 rotates around the inner wall of the stirring kettle 210, meanwhile, the second crankshaft 221 drives the second gear 240 to rotate around the gear ring 250, and the second gear 240 can drive the stirring paddle 243 to rotate and stir to obtain a mixed solution.
The method comprises the following specific implementation steps: the delivery pipe 331 is communicated with an external delivery pipe through a flange pipe, the second electromagnetic valve 333 is opened to enable the raw materials to enter the metering cylinder 3131, and when the raw materials are accumulated to submerge the highest point of the discharge channel, the raw materials are sucked into the stirring kettle 210 from the discharge channel through the siphon principle; after the raw materials enter the stirring kettle 210, starting the first driving motor 111 to electrify and drive the driving shaft 112 and the driving bevel gear 113 to rotate, so that the driven bevel gear 114 drives the rotating shaft 115 and the eccentric wheel 124 to rotate, the eccentric wheel 124 can drive the hollow wheel 121 and the moving rod 122 to transversely reciprocate along the length direction, so that the first connecting rod 131 transversely reciprocates in the movable hole 410, the second connecting rod 132 transversely reciprocates along with the first connecting rod 131 to push the second crankshaft 221, so that the second crankshaft 221 drives the first rotating disc 135 to rotate, and drives the stirring kettle 210 to rotate so as to enable the materials to oscillate and fuse; the second driving motor 220 is started to be powered on to drive the second crankshaft 221 to rotate, so that the stirring paddle 243 rotates around the inner wall of the stirring kettle 210, meanwhile, the second crankshaft 221 drives the second gear 240 to rotate around the gear ring 250, and the second gear 240 can drive the stirring paddle 243 to rotate and stir to obtain a mixed solution.
It should be noted that the model specifications of the first driving motor 111, the second driving motor 220, the first electromagnetic valve 261, the third driving motor 321, and the second electromagnetic valve 333 need to be determined by type selection according to the actual specification of the device, and the specific type selection calculation method adopts the prior art in the field, and therefore, detailed description is omitted.
The power supply of the first driving motor 111, the second driving motor 220, the first solenoid valve 261, the third driving motor 321, and the second solenoid valve 333 and the principle thereof will be apparent to those skilled in the art and will not be described in detail herein.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes may be made to the present invention by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. An antigen emulsifying device, comprising:
the rack comprises a first layer of partition plates, a second layer of partition plates and a third layer of partition plates which are sequentially distributed in an array manner from top to bottom, and supporting plates positioned on two sides of the first layer of partition plates, the second layer of partition plates and the third layer of partition plates, wherein movable holes are formed in the tops of the second layer of partition plates;
the vibrating device comprises a driving piece, a reciprocating piece and a rotating piece, wherein the driving piece is used for driving the reciprocating piece to reciprocate and transversely move along the length direction, so that the rotating piece continuously drives the stirring kettle to rotate, and raw materials are fully fused;
the driving piece comprises a first driving motor, a driving shaft, a driving bevel gear, a driven bevel gear and a rotating shaft, the first driving motor is fixedly installed at the bottom of the third layer of partition plate, the output end of the first driving motor is fixedly connected with the driving shaft, one end of the driving shaft is sleeved with the driving bevel gear, the driving bevel gear is in meshing connection with the driven bevel gear, the rotating shaft is fixedly connected with the inner shaft of the driven bevel gear, and one end of the rotating shaft penetrates through the third layer of partition plate and extends to the position above the third layer of partition plate;
the reciprocating element is positioned above the third layer of partition plate and comprises a hollow wheel, a moving rod, a support sleeve and an eccentric wheel, the moving rod is integrally formed on two sides of the hollow wheel, the support sleeve is arranged on the surface of the moving rod and fixedly connected above the third layer of partition plate, the eccentric wheel is arranged inside the hollow wheel, and one end of the rotating shaft, which is positioned above the third layer of partition plate, is fixedly connected with an inner shaft of the eccentric wheel;
the rotating part comprises a first connecting rod, a second connecting rod, a bearing seat, a first crankshaft and a first rotary table, one end of the first connecting rod is fixedly connected with one end of the moving rod, the other end of the first connecting rod penetrates through the movable hole and extends to the position above the second layer of partition plate, one end of the first connecting rod, which is positioned above the second layer of partition plate, is connected with the second connecting rod, the other end of the second connecting rod is rotatably connected with the first crankshaft, one end of the first crankshaft is rotatably connected with the bearing seat, the other end of the first crankshaft penetrates through the first layer of partition plate and extends to the position above the first layer of partition plate, and one end of the first crankshaft, which is positioned above the first layer of partition plate, is fixedly connected with the first;
an emulsifying device, the emulsifying device comprises a stirring kettle, a second driving motor, a first gear, a second gear and a gear ring, the stirring kettle is fixedly connected with the top of the first rotary table, the top of the stirring kettle is fixedly provided with the second driving motor, the output end of the second driving motor is fixedly connected with a second crankshaft, the second crankshaft is positioned in the stirring kettle, one end of the second crankshaft is fixedly connected with a connecting sleeve, the first gear sleeve is arranged on the surface of the first crankshaft, the second gear is in meshed connection with the first gear, the inner shaft of the second gear is fixedly connected with a transmission rod, the transmission rod is rotatably connected with the connecting sleeve, one end of the transmission rod is fixedly connected with a mounting plate, the bottom of the mounting plate is provided with a stirring paddle, and the gear ring is fixedly connected with the inner wall of the stirring kettle, the second gear is in meshed connection with the gear ring.
The metering device comprises a metering piece for controlling the material feeding amount, a transmission piece for adjusting the material feeding amount proportion and a material conveying piece for controlling the material conveying speed.
2. The antigen emulsifying device of claim 1, wherein a circular slideway is arranged at the top of the first layer of partition plate, and a pulley is arranged at the bottom of the first rotating disc and is connected with the slideway in a sliding manner.
3. The antigen emulsifying device of claim 1, wherein the number of the paddles is at least one, the mounting plate is circular, and the paddles are distributed around the bottom of the mounting plate.
4. The antigen emulsifying device according to claim 1, wherein a discharge pipe is connected to the bottom of the stirring tank, and a first electromagnetic valve is installed at one end of the discharge pipe.
5. The antigen emulsifying device according to claim 1, wherein the metering member comprises a second rotary disc, mounting holes, a metering device and a concentric shaft, the second rotary disc is embedded into the top of the stirring kettle and is rotatably connected with the stirring kettle, a plurality of mounting holes are distributed around the top of the second rotary disc, the metering device is arranged in each of the plurality of mounting holes, and the concentric shaft is fixedly connected with the axis of the second rotary disc.
6. The antigen emulsifying device according to claim 5, wherein the meter comprises a metering cylinder, a flow-assisting channel, a feeding channel and a discharging channel, the feeding channel, the flow-assisting channel and the discharging channel for accommodating raw material flow are arranged inside the metering cylinder, the feeding channel, the flow-assisting channel and the discharging channel are sequentially communicated to form an inverted U-shaped discharging channel, and the discharging channel extends to the inside of the stirring kettle.
7. The antigen emulsifying device of claim 6, wherein the discharge channel of a plurality of meters has a non-uniform level at its highest point.
8. The antigen emulsifying device according to claim 5, wherein the transmission member comprises a third driving motor, a synchronizing shaft, a first rotating wheel, a second rotating wheel and a transmission belt, the third driving motor is fixedly mounted at the rear side of the stirring kettle, the output end of the third driving motor is fixedly connected with the synchronizing shaft, one end of the synchronizing shaft is sleeved with the first rotating wheel, the second rotating wheel is sleeved at one end of the concentric shaft, and the first rotating wheel and the second rotating wheel are rotatably connected through the transmission belt.
9. The antigen emulsifying device according to claim 1, wherein the material conveying member comprises a conveying pipe, supporting legs, a second electromagnetic valve and a flange plate, the supporting legs are arranged on the surface of the conveying pipe and fixedly connected to the top of the stirring kettle, the second electromagnetic valve is mounted on the conveying pipe, and one end of the conveying pipe is connected with the flange plate.
10. The working method of the antigen emulsifying device is applied to the antigen emulsifying device according to any one of claims 1 to 9, and is characterized by comprising the following steps:
s1, metering feed: the conveying pipe is communicated with an external conveying pipe through a flange pipe, a second electromagnetic valve is started to enable the raw materials to enter the metering cylinder, and when the raw materials are accumulated to submerge the highest point of the discharge channel, the raw materials are sucked into the stirring kettle from the discharge channel through a siphon principle;
s2, oscillation fusion: after raw materials enter the stirring kettle, a first driving motor is started to be electrified to drive a driving shaft and a driving bevel gear to rotate, so that a driven bevel gear can drive a rotating shaft and an eccentric wheel to rotate, the eccentric wheel can drive a hollow wheel and a moving rod to transversely reciprocate along the length direction, the first connecting rod transversely reciprocates in a movable hole, the second connecting rod transversely reciprocates along with the first connecting rod to push a second crankshaft, the second crankshaft drives a first rotating disc to rotate, and the stirring kettle is driven to rotate to enable the materials to be oscillated and fused;
s3, fusion and stirring: and a second driving motor is started to be electrified to drive a second crankshaft to rotate, so that the stirring paddle rotates around the inner wall of the stirring kettle, and meanwhile, the second crankshaft drives a second gear to rotate around the gear ring, so that the second gear drives the stirring paddle to perform autorotation stirring to obtain a mixed solution.
CN202110361534.7A 2021-04-02 2021-04-02 Antigen emulsifying device and working method thereof Active CN113083100B (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103759780A (en) * 2014-01-08 2014-04-30 天津大学 Novel tarry high-sticky liquid material siphon measurement device
CN106975401A (en) * 2017-05-11 2017-07-25 浙江班萘特复合材料有限公司 A kind of new material highly-efficient processing mixer
CN209791443U (en) * 2019-03-05 2019-12-17 湖北丰乐生态肥业有限公司 Emulsification device is used in compound fertilizer production
CN111282488A (en) * 2020-03-31 2020-06-16 常付才 Chemical raw material mixing device
CN211358577U (en) * 2019-12-19 2020-08-28 吉安市中香天然植物有限公司 Natural plant essential oil high-shear vacuum emulsification tank
CN212391098U (en) * 2020-04-30 2021-01-22 湖南省新漾食品有限公司 A steamed material quantitative weighing device for duck neck processing

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103759780A (en) * 2014-01-08 2014-04-30 天津大学 Novel tarry high-sticky liquid material siphon measurement device
CN106975401A (en) * 2017-05-11 2017-07-25 浙江班萘特复合材料有限公司 A kind of new material highly-efficient processing mixer
CN209791443U (en) * 2019-03-05 2019-12-17 湖北丰乐生态肥业有限公司 Emulsification device is used in compound fertilizer production
CN211358577U (en) * 2019-12-19 2020-08-28 吉安市中香天然植物有限公司 Natural plant essential oil high-shear vacuum emulsification tank
CN111282488A (en) * 2020-03-31 2020-06-16 常付才 Chemical raw material mixing device
CN212391098U (en) * 2020-04-30 2021-01-22 湖南省新漾食品有限公司 A steamed material quantitative weighing device for duck neck processing

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