CN113069613A - Navel cord blood rewarming leak protection box - Google Patents
Navel cord blood rewarming leak protection box Download PDFInfo
- Publication number
- CN113069613A CN113069613A CN202110301330.4A CN202110301330A CN113069613A CN 113069613 A CN113069613 A CN 113069613A CN 202110301330 A CN202110301330 A CN 202110301330A CN 113069613 A CN113069613 A CN 113069613A
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- Prior art keywords
- cord blood
- rewarming
- base
- buckle
- leakage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0259—Apparatus for treatment of blood or blood constituents not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses an umbilical cord blood rewarming and leakage-preventing box which comprises a base, a closing cover and a conduit closing buckle; the base is provided with a blood bag limiting groove which is concavely arranged from the top surface of the base, the front side of the base is provided with a first side wall, the first side wall is provided with a through hole for a blood bag conduit to pass through, and the through hole is connected with the blood bag limiting groove; the closing cover can be buckled on the top surface of the base in an opening and closing manner; the catheter closing buckle is movably arranged on the outer side of the first side wall and used for pressing and connecting the blood bag catheter. This navel cord blood rewarming leak protection box sets up the closed buckle of pipe, can in time use closed buckle closed pipe to close the heat seal mouth that easily breaks promptly at rewarming initial stage after the navel cord blood on the pipe melts to the risk that the heat seal mouth breaks appears in avoiding the freezing bag rewarming in-process of navel cord blood.
Description
Technical Field
The invention relates to the technical field of thawing and rewarming of umbilical cord blood, in particular to a novel umbilical cord blood rewarming and leakage-preventing box.
Background
Umbilical Cord Blood (UCB) is a source of hematopoietic stem cells that replaces bone marrow for transplantation of blood diseases in children and adults. Since the first sibling cord blood transplantation treatment fanconi anemia in the world was developed in france in 1988, the medical value of cord blood was initially recognized, and cord blood gradually developed into the third hematopoietic stem cell source following bone marrow and peripheral blood. There are approximately 35,000 hematopoietic transplants of umbilical cord worldwide, and over 730,000 umbilical cord units are available today for hematological patients who require allogeneic donors. In addition, the cord blood is rich in various stem cells and various cytokines, and is widely applied to clinical tests of regenerative medicine and nerve repair at present.
Cord blood has several advantages, including immediate availability, no risk to donors, and low risk of acute and chronic graft-versus-host disease despite the disparity in major Human Leukocyte Antigens (HLA). Umbilical Cord Blood Transfer (CBT) from non-relatives donors has been increasingly used as an alternative source of stem cells for patients without hla-compatible relatives or non-relatives donors. Although the incidence of cord blood freezing bag rupture is low, the rupture is a known risk of cord blood transplantation, and the heat sealing opening is a fragile link which is easy to rupture when the cord blood freezing bag is rewarming, once the freezing bag ruptures, the cord blood in the bag is exposed to a bacteria environment, which directly results in the cord blood being unusable, delays the optimal treatment period of a patient needing transplantation, and therefore, the protection of the cord blood from rupture of the freezing bag in the process of thawing and rewarming is very important.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a novel umbilical cord blood rewarming and leakage-proof box, which ensures that the umbilical cord blood is uniformly heated in a water bath and closes a heat seal port which is easy to break at the initial rewarming stage so as to avoid the risk of the heat seal port breaking in the rewarming process of an umbilical cord blood freezing bag.
In order to achieve the above purpose, the invention provides the following technical scheme:
an umbilical cord blood rewarming and leakage-proof box comprises a base, a closing cover and a conduit closing buckle; the base is provided with a blood bag limiting groove which is concavely arranged from the top surface of the base, the front side of the base is provided with a first side wall, the first side wall is provided with a through hole for a blood bag conduit to pass through, and the through hole is connected with the blood bag limiting groove; the closing cover can be buckled on the top surface of the base in an opening and closing manner; the catheter closing buckle is movably arranged on the outer side of the first side wall and used for pressing and connecting the blood bag catheter.
Preferably, an extension plate extending outwards is arranged at the upper end of the first side wall, the extension plate is positioned at the upper side of the through hole, and the end part of the extension plate is buckled with the closed buckle of the conduit.
As a preferable scheme, the first side wall is provided with a connecting part, and the connecting part is positioned at the lower side of the through hole; the closed buckle of pipe has a crimping portion and buckle portion, the one end of crimping portion with connecting portion are articulated, and buckle portion is connected to the other end, and the upside of crimping portion is equipped with first wedge briquetting, buckle portion upwards extends and lock the tip of convex plate.
As a preferable scheme, a second wedge-shaped pressing block matched with the first wedge-shaped pressing block is arranged on the lower side of the extension plate, the lower end of the second wedge-shaped pressing block and the upper end of the first wedge-shaped pressing block are staggered front and back in the state that the buckle part is buckled with the convex plate, and the lower end of the second wedge-shaped pressing block is lower than the top end of the first wedge-shaped pressing block.
As a preferred scheme, the rear side that the base was equipped with is equipped with the suspension hangers.
Preferably, the closure is hinged to the top end of the first side wall.
Preferably, the closing cover is provided with an opening which is communicated up and down.
As a preferable scheme, the rear side of the first side wall is provided with three through holes which respectively correspond to three interfaces of the blood bag.
Compared with the prior art, the invention has the following beneficial effects:
1. the umbilical cord blood rewarming leakage-proof box provided by the invention is provided with the conduit closing buckle, and after the umbilical cord blood on the conduit is melted, the closed conduit closing buckle can be used for closing the heat seal port which is easy to break in the initial rewarming stage so as to avoid the risk of the heat seal port breaking in the rewarming process of the umbilical cord blood freezing bag;
2. when the cord blood water bath rewarming, the cord blood bag is fixed in the blood bag limiting groove and can be fully rewarmed by the water bath, so that the phenomenon that the time is too long due to uneven temperature or poor heat absorption of the water bath during rewarming is avoided, and the cord blood hematopoietic stem cells frozen by liquid nitrogen are broken due to temperature difference in the rewarming process, thereby reducing the cell activity.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
FIG. 1 is a top view of the anti-leakage box for rewarming cord blood in the present invention;
FIG. 2 is a front view of the anti-leakage box for rewarming cord blood in the present invention;
FIG. 3 is a side view of the anti-leakage box for rewarming cord blood in the present invention;
FIG. 4 is a schematic view of the use of the leakage-proof box for rewarming cord blood in the present invention;
in the figure:
a base 1; a suspension hanger 11; a first side wall 12; a connecting portion 121; a through hole 13; an extension plate 14; a second wedge-shaped pressing block 141; a blood bag limiting groove 15; closing the lid 2; an opening 21; a vessel closing buckle 3; a crimping part 31; a first wedge-shaped pressing block 311; a latch portion 32; a cord blood bag 100; a blood bag conduit 101.
Detailed Description
For a better understanding of the objects, structure, features, and functions of the invention, reference should be made to the drawings and detailed description that follow. It should be noted that the features illustrated in the drawings are not necessarily drawn to scale. Moreover, the described embodiments are a few embodiments of the invention, rather than all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the invention without any inventive step, are within the scope of protection of the invention.
Unless otherwise defined, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this disclosure belongs. The use of "first," "second," and similar terms in this disclosure is not intended to indicate any order, quantity, or importance, but rather is used to distinguish one element from another. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "upper", "lower", "left", "right", "front", "rear", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly. In addition, in the description of the present invention, "a plurality" means two or more unless otherwise specified.
Examples
Referring to fig. 1-4, the present invention provides a leakage-proof box for recovering the temperature of umbilical cord blood, which comprises a base 1, a closure cover 2 and a vessel closure buckle 3; the base is provided with a blood bag limiting groove 15 which is concavely arranged from the top surface of the base downwards and is used for containing a cord blood bag 100, the front side of the base is provided with a first side wall 12, the first side wall 12 is provided with a through hole 13 for a blood bag conduit to pass through, and the through hole is connected with the blood bag limiting groove; the closing cover 2 can be buckled on the top surface of the base in an opening and closing manner, and in the embodiment, the top end of the first side wall of the closing cover is hinged; the catheter closing buckle 3 is movably arranged on the outer side of the first side wall and used for crimping the blood bag catheter, so that the blood bag catheter is closed to avoid the risk of heat sealing and cracking in the process of rewarming the umbilical cord blood freezing bag.
The upper end of the first side wall 12 is provided with an extension plate 14 extending outwards, the extension plate 14 is positioned on the upper side of the through hole, and the end part of the extension plate is buckled with the conduit closing buckle 3.
The first side wall is provided with a connecting part 121, and the connecting part 121 is positioned at the lower side of the through hole; the catheter closing buckle 3 is provided with a pressing part 31 and a buckling part 32, one end of the pressing part is hinged with the connecting part, the other end of the pressing part is connected with the buckling part, a first wedge-shaped pressing block 311 is arranged on the upper side of the pressing part, and the buckling part 32 extends upwards and buckles the end part of the convex plate. A second wedge-shaped pressing block 141 matched with the first wedge-shaped pressing block is arranged on the lower side of the extension plate 14, the lower end of the second wedge-shaped pressing block 141 and the upper end of the first wedge-shaped pressing block 311 are staggered front and back in the state that the buckling part is buckled with the convex plate 14, and the lower end of the second wedge-shaped pressing block 141 is higher than the lower end of the first wedge-shaped pressing block 311. Through the first wedge briquetting 311 and the second wedge briquetting 141 crimping blood bag pipe 101 that stagger for blood bag pipe forms two bending zones, is favorable to promoting the closed effect of pipe.
The rear side that the base was equipped with is equipped with suspension hangers 11. After the umbilical cord blood is thawed again, a nurse or a family member is required to take the umbilical cord blood up by hand or put the umbilical cord blood on a higher platform, so that the problem of inconvenient operation exists. After the umbilical cord blood rewarming and leakage-proof box is used, the rewarmed umbilical cord blood can be hung on a floor type infusion support through the hanging lugs 11, so that the rewarmed umbilical cord blood can smoothly flow out of the freezing bag. Thereby promoting the practical convenience of the umbilical cord blood.
The closing cover is provided with an up-and-down through opening 21, when the opening is arranged to facilitate the cord blood rewarming, warm water can enter the box body through the opening 21 to directly contact with the cord blood bag, so that the water bath can be fully implemented.
In this embodiment, the rear side of the first side wall is provided with three through holes 13 corresponding to three ports of the cord blood bag 100, so as to better adapt to the shape of the blood bag and enable the water bath to be fully carried out.
Referring to fig. 1-4, the specific usage of the leakage-proof box for rewarming umbilical cord blood is as follows:
firstly, placing an umbilical cord blood bag taken out from liquid nitrogen into a blood bag limiting groove of an umbilical cord blood rewarming and leakage-preventing box, respectively inserting three catheter positions of the umbilical cord blood bag into three through holes 13 at the front end of a blood bag limiting groove 15, and enabling a blood bag catheter 101 at the rightmost end to penetrate through a catheter closing buckle 3; subsequently, the cord blood bag is fixed by closing the closing cover 2, put into a sterile plastic bag and heated in a water bath at 40 ℃. When the blood on the catheter is melted after the primary rewarming, a worker presses the lower end of the catheter closing buckle to enable the catheter closing buckle to buckle the extension plate 14, so that the blood bag catheter is closed; then, taking the cord blood rewarming leak-proof box out of the sterile plastic bag, directly placing the cord blood rewarming leak-proof box in a water bath box for water bath heating, and slightly oscillating left and right to ensure that water near the cord blood bag 100 is in a flowing state and the water bath temperature near the blood bag is stable; after the cord blood is completely rewarming and unfrozen for about 3 minutes, the cord blood rewarming leakage-proof box is hung on a floor type infusion support so that a doctor can conveniently carry out subsequent cord blood transplantation treatment.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. An umbilical cord blood rewarming and leakage-preventing box is characterized by comprising a base, a closing cover and a conduit closing buckle; the base is provided with a blood bag limiting groove which is concavely arranged from the top surface of the base, the front side of the base is provided with a first side wall, the first side wall is provided with a through hole for a blood bag conduit to pass through, and the through hole is connected with the blood bag limiting groove; the closing cover can be buckled on the top surface of the base in an opening and closing manner; the catheter closing buckle is movably arranged on the outer side of the first side wall and used for pressing and connecting the blood bag catheter.
2. The leakage-proof box for rewarming cord blood as claimed in claim 1, wherein the upper end of the first sidewall is provided with an extension plate extending outwards, the extension plate is located on the upper side of the through hole, and the end of the extension plate is buckled with the closed buckle of the conduit.
3. The leakage-proof box for rewarming cord blood as claimed in claim 2, wherein the first sidewall is provided with a connecting part, and the connecting part is positioned at the lower side of the through hole; the closed buckle of pipe has a crimping portion and buckle portion, the one end of crimping portion with connecting portion are articulated, and buckle portion is connected to the other end, and the upside of crimping portion is equipped with first wedge briquetting, buckle portion upwards extends and lock the tip of convex plate.
4. The umbilical cord blood rewarming and leakage-preventing box of claim 3, wherein a second wedge-shaped pressing block matched with the first wedge-shaped pressing block is arranged on the lower side of the extension plate, the lower end of the second wedge-shaped pressing block and the upper end of the first wedge-shaped pressing block are staggered front and back in a state that the buckling part is buckled with the convex plate, and the lower end of the second wedge-shaped pressing block is lower than the top end of the first wedge-shaped pressing block.
5. The leakage-proof box for rewarming cord blood as claimed in claim 1, wherein the rear side of the base is provided with a hanging lug.
6. The leakage-proof box for rewarming cord blood as claimed in claim 1, wherein said closing cover is hinged to the top end of said first side wall.
7. The anti-leakage box for rewarming cord blood as claimed in claim 6, wherein said closing cover has an opening passing through it.
8. The leakage-proof box for rewarming cord blood as claimed in claim 1, wherein the rear side of the first sidewall is provided with three through holes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110301330.4A CN113069613A (en) | 2021-03-22 | 2021-03-22 | Navel cord blood rewarming leak protection box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110301330.4A CN113069613A (en) | 2021-03-22 | 2021-03-22 | Navel cord blood rewarming leak protection box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113069613A true CN113069613A (en) | 2021-07-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110301330.4A Pending CN113069613A (en) | 2021-03-22 | 2021-03-22 | Navel cord blood rewarming leak protection box |
Country Status (1)
| Country | Link |
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| CN (1) | CN113069613A (en) |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN210338964U (en) * | 2019-07-30 | 2020-04-17 | 广东先康达生物科技有限公司 | Liquid nitrogen storage hematopoietic stem cell blood bag cryopreservation box |
| CN211704867U (en) * | 2020-02-14 | 2020-10-20 | 中国人民解放军总医院第四医学中心 | Expander with flat driving lever of exhibition |
| CN111905200A (en) * | 2020-08-19 | 2020-11-10 | 南京市儿童医院 | Regulation and control type hematology department blood transfusion auxiliary device |
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2021
- 2021-03-22 CN CN202110301330.4A patent/CN113069613A/en active Pending
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| US20100281886A1 (en) * | 2006-09-11 | 2010-11-11 | Core Dynamics Limited | Systems, devices and methods for freezing and thawing biological materials |
| DE102010020374A1 (en) * | 2010-05-12 | 2011-11-17 | Bms Medical Technologies Gmbh | Protective sheath for blood bag in e.g. clinic, has pocket made of plastic and comprising lockable aperture and vent hole, bag arranged at inner side of pocket through aperture, and radio frequency identification element arranged on pocket |
| CN101861858A (en) * | 2010-05-26 | 2010-10-20 | 金卫医疗科技(上海)有限公司 | Medical profound hypothermia storage bag having function of protecting liquid inlet pipe |
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Application publication date: 20210706 |