CN113069120A - Photoelectric fusion type brain electrode - Google Patents
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- CN113069120A CN113069120A CN202110377279.5A CN202110377279A CN113069120A CN 113069120 A CN113069120 A CN 113069120A CN 202110377279 A CN202110377279 A CN 202110377279A CN 113069120 A CN113069120 A CN 113069120A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0295—Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
Abstract
The invention discloses a photoelectric fusion brain electrode which comprises an electrode body, wherein a photoelectric sensor which is positioned in the middle of the electrode body and is based on photoplethysmography is arranged on the electrode body, and an electrode assembly which surrounds the outer side of the photoelectric sensor is also arranged on the electrode body. The photoelectric fusion brain electrode can simultaneously acquire scalp blood flow signals and brain electrical signals at the same acquisition point, is convenient for observing the synchronous change of the two signals at the acquisition point, can acquire a large amount of human physiological information through analysis, and is beneficial to multichannel brain electrical health monitoring and analysis; in addition, when the electro-optical fusion type brain electrode is used, hairs can be pulled away through the electrode assembly, the problem that the detection accuracy of the photoelectric sensor is affected due to the fact that signal absorption is weakened due to the hairs is solved, the electrode assembly arranged around the outer side of the photoelectric sensor can block optical signals which are emitted by the photoelectric sensor and scattered outwards, and the optical signals are prevented from being scattered into the nearby electro-optical fusion type brain electrode to affect the detection result of the nearby electro-optical fusion type brain electrode.
Description
Technical Field
The invention relates to the technical field of human body monitoring, in particular to a photoelectric fusion type brain electrode.
Background
Eeg (electrophosphoraphy) refers to a method of recording brain activity using electrodes. The scalp electroencephalogram signals contain a large amount of information closely related to human health, and important references are provided for disease prevention and brain-computer interface research.
Ppg (photoplethysmography) refers to a technical method for measuring and recording the pulse state of a blood vessel by utilizing a photoelectric volume pulse wave so as to obtain health parameters such as heart rate, blood oxygen saturation and the like.
EEG and PPG are applied to obtain EEG signals and blood flow signals respectively, the EEG signals and the blood flow signals can be comprehensively analyzed to obtain the health condition of a human body, in the prior art, the two signals are obtained separately and independently, information collected at different positions has certain deviation, and the two information lack correlation and comprise the reference of positions and time; when PPG is adopted to acquire blood flow information at different positions, adjacent sensors generate optical signal crosstalk to influence measurement accuracy.
Accordingly, the prior art is yet to be improved and developed.
Disclosure of Invention
In view of the defects of the prior art, an object of the embodiments of the present application is to provide a photoelectric fusion brain electrode, which can simultaneously acquire an electroencephalogram signal and a blood flow signal of the same acquisition point, is beneficial to comprehensive analysis of human health, can also avoid optical crosstalk generated by a proximity sensor, and improves PPG measurement accuracy.
The embodiment of the application provides a photoelectric fusion brain electrode, including the electrode body, be equipped with on the electrode body and be located its middle part and based on the photoelectric sensor of photoplethysmography, still be equipped with the electrode subassembly that encircles in the photoelectric sensor outside on the electrode body.
The photoelectric fusion type brain electrode can simultaneously acquire scalp blood flow signals and brain electrical signals at the same acquisition point, and is convenient for observing the synchronous change of the two signals at the acquisition point; in addition, the electrode assembly arranged around the outer side of the photoelectric sensor can block the light signal emitted by the photoelectric sensor and scattered outwards, so that the problem of light crosstalk is avoided.
The photoelectric fusion brain electrode is characterized in that the photoelectric sensor comprises a plurality of LED light sources which are arranged side by side and used for emitting light signals and a detector which is arranged on one side of the LED light sources and used for receiving reflected light signals.
The photoelectric fusion brain electrode is characterized in that the number of the LED light sources is three, and the LED light sources respectively emit green light, red light and infrared light.
The photoelectric fusion brain electrode is characterized in that the LED light source and the detector are respectively positioned on two sides of the center of the electrode body.
The electro-optical fusion type brain electrode is characterized in that the electrode assembly comprises more than two electrode probes which are arrayed in an equidistant mode in the circumference.
The photoelectric fusion type brain electrode is characterized in that the two adjacent electrode probes are arranged in a staggered manner.
The photoelectric fusion type brain electrode is characterized in that the electrode body is cylindrical, and the axis line of the electrode body is superposed with the axis of the electrode probe array.
The electro-optical fusion type brain electrode is characterized in that the electrode probe is one of cylindrical, truncated cone-shaped and conical.
The photoelectric fusion type brain electrode is characterized in that the electrode probe is a microneedle electrode.
The photoelectric fusion brain electrode is characterized in that a groove for mounting a photoelectric sensor is formed in the middle of the electrode body, and the electrode assembly is located outside the groove.
From the above, the photoelectric fusion brain electrode provided by the embodiment of the application can simultaneously acquire the scalp blood flow signal and the brain electrical signal at the same acquisition point, is convenient for observing the synchronous change of the two signals at the acquisition point, can obtain a large amount of human physiological information through analysis, provides important basis for diagnosis and prevention of diseases, brain function research and the like, and is beneficial to multi-channel brain electrical health monitoring and analysis; in addition, when the electro-optical fusion type brain electrode is used, hairs can be pulled away through the electrode assembly, the problem that the detection accuracy of the photoelectric sensor is affected due to the fact that signal absorption is weakened due to the hairs is solved, the electrode assembly arranged around the outer side of the photoelectric sensor can block optical signals which are emitted by the photoelectric sensor and scattered outwards, and the optical signals are prevented from being scattered into the nearby electro-optical fusion type brain electrode to affect the detection result of the nearby electro-optical fusion type brain electrode.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments of the present application will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and that those skilled in the art can also obtain other related drawings based on the drawings without inventive efforts.
Fig. 1 is a perspective view of a brain electrode in electro-optical fusion according to an embodiment of the present application.
Fig. 2 is a schematic top view of a electrofusion electroencephalogram electrode according to an embodiment of the present application.
Fig. 3 is a schematic side view of a electro-optical fusion type electroencephalograph according to an embodiment of the present application.
Reference numerals: 1. an electrode body; 2. a photosensor; 3. an electrode assembly; 11. a groove; 21. an LED light source; 22. a detector; 23. a circuit board; 24. an electronic device; 25. a raised end.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. The components of the embodiments of the present application, generally described and illustrated in the figures herein, can be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present application, presented in the accompanying drawings, is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall fall within the protection scope of the present application.
As shown in fig. 1 to 3, the present embodiment provides a brain electrode of electrofusion type, which includes an electrode body 1, a photoelectric sensor 2 based on photoplethysmography is disposed on the electrode body 1, and an electrode assembly 3 surrounding the photoelectric sensor 2 is further disposed on the electrode body 1.
The photoelectric sensor 2 based on the photoplethysmography is the photoelectric sensor 2 based on ppg (photoplethysmography), that is, the photoelectric sensor 2 can record the pulsation state of a blood vessel by using the measurement of the photoplethysmography pulse wave, so as to obtain health parameters such as heart rate, blood oxygen saturation and the like, and the photoelectric sensor should include a light signal emitting end, a reflected light signal receiving end and a signal analysis module.
The electrode assembly 3 is used to measure an electroencephalogram (EEG) signal.
The photoelectric fusion type brain electrodes are usually used simultaneously, namely the plurality of brain electrodes are fixed on different positions of the head at the same time to acquire signals at different positions, and brain signals and blood flow signals in different positions can be acquired at the same time.
The photoelectric fusion brain electrode is provided with a photoelectric sensor 2 based on photoplethysmography and an electrode assembly 3, wherein the photoelectric sensor 2 is used for detecting brain activity, and the electrode assembly 3 is used for measuring scalp brain electrical signals; the photoelectric fusion brain electrode can be used for simultaneously collecting scalp blood flow signals and brain electrical signals at the same collecting point, so that synchronous change of the two signals at the collecting point can be observed conveniently, a large amount of human physiological information can be obtained through analysis, and important basis is provided for diagnosis and prevention of diseases, brain function research and the like.
More specifically, because a plurality of photoelectric fusion brain electricity devices of the embodiment of the present application are used simultaneously, two signals generated at different positions can be compared, and the physiological conditions of different positions of the head can be analyzed, thereby providing further important basis for diagnosis and prevention of diseases, brain function research, and the like.
When the photoelectric fusion type brain electrode provided by the embodiment of the application is used, hairs can be pulled away through the electrode assembly 3, the problem that the detection accuracy of the photoelectric sensor 2 is affected due to the fact that signal absorption caused by the hairs is weakened is avoided, in addition, the electrode assembly 3 arranged on the outer side of the photoelectric sensor 2 in a surrounding mode can block light signals which are emitted by the photoelectric sensor 2 and scattered outwards, and the problem that the light signals are scattered to the nearby photoelectric fusion type brain electrode to affect the detection result of the nearby photoelectric fusion type brain electrode, namely, the problem that optical crosstalk is caused is avoided.
More specifically, when the optical signal emitted by the photoelectric sensor 2 is scattered to the electrode assembly 3, the scattered optical signal is reflected in the electrode assembly 3 for multiple times and absorbed by the electrode assembly 3 to be attenuated, so that the scattered optical signal is prevented from departing from the current position of the photoelectric fused brain electrode and entering the adjacent photoelectric fused brain electrode to influence the measurement result of the photoelectric sensor 2 adjacent to the photoelectric fused brain electrode.
The middle part of the electrode body 1 of the electro-optical fusion type brain electrode in the embodiment of the present application is provided with a signal wire connected to an external signal display device or an analysis device, and after the signal is collected by the brain electrode, the signal wire transmits the signal to the external signal display device or the analysis device.
In some preferred embodiments, the photosensor 2 includes several LED light sources 21 arranged side by side for emitting light signals and a detector 22 arranged at one side of the LED light sources 21 for receiving reflected light signals; the LED light source 21 emits light signals for detection towards the scalp, the light sources with different wavelengths have different detection depths for cerebral cortex, the light signals are reflected by the cerebral cortex to form reflected light signals, the detector 22 is used for receiving and measuring the reflected light signals, the detector 22 can measure reflected light signals reflected back in blood of the cerebral cortex to obtain an electrocardio R-R interval, atrial fibrillation can be detected through analysis, and cerebral apoplexy can be judged and predicted by measuring cerebral vascular hemodynamics indexes; part of the reflected light signal formed by the reflection of the light signal is scattered outside the electrode body 1, and the electrode assembly 3 can block the reflected light signal which is emitted by the photoelectric sensor 2 and scattered outside.
The detector 22 reads the reflected light signals reflected from the scalp and converts the signals into corresponding blood flow signals to measure the health parameters such as heart rate, scalp blood flow, blood oxygen saturation, etc.
In addition, the plurality of LED light sources 21 are arranged side by side, and can generate light signals emitted in parallel, so as to ensure that the light signals of different LED light sources 21 have similar incident angles, which is beneficial for a single detector 22 to receive reflected light signals generated by the reflection of the light signals from different LED light sources 21.
In some preferred embodiments, the photoelectric sensor 2 further comprises a circuit board 23 fixed on the electrode body 1 and an electronic device 24 disposed on the circuit board 23, the LED light source 21 and the detector 22 are disposed on the circuit board 23, the LED light source 21 is used for emitting a detection light signal, the detector 22 is used for receiving an emission light signal emitted from the scalp, and the circuit board 23 and the electronic device 24 are used for converting the reflection light signal into an electrical signal for output.
In some preferred embodiments, the circuit board 23 is provided with a protruding end 25, the LED light source 21 and the detector 22 are both disposed on the protruding end 25, and the electronic device 24 is disposed on the circuit board 23 at an outer portion of the protruding end 25, so as to prevent the electronic device 24 from interfering with the LED light source 21 to emit the light signal and prevent the electronic device 24 from interfering with the detector 22 to receive the reflected light signal.
In some preferred embodiments, there are three LED light sources 21, and the LED light sources emit green light, red light and infrared light respectively; the detection depth of green light, red light and infrared light to the cerebral cortex is sequentially increased, and the interference of the infrared light by the skin surface (sweating, oil bleeding and the like) is smaller, so that the fused brain electrode can adapt to various application occasions and can acquire blood information of different depths in different cerebral cortex.
Wherein, furthermoreIn other words, the red and infrared light generated by the LED light source 21 in the light sensor is directed to oxygenated hemoglobin (Hb) and hemoglobin (HbO) in the brain2) The absorption of the red light is different, the absorption coefficient of the red light to the hemoglobin is high, the absorption coefficient of the infrared light to the oxyhemoglobin is high, and the parameters of the blood oxygen saturation can be obtained by measuring PPG signals of the red light and the oxyhemoglobin and comparing the two PPG signals.
Among them, the green light wavelength is preferably 525nm, the red light wavelength is preferably 660nm, and the infrared light wavelength is preferably 940 nm.
In general, the base body of the brain electrode is usually soft in order to allow the upper electrode probe to fit the outer shape of the head for contact monitoring, so that the electrode body 1 of the brain electrode in the embodiment of the present invention is soft, i.e., can be bent with respect to the outer shape of the head so that the electrode assembly 3 can be tightly connected to the head.
In some preferred embodiments, the LED light source 21 and the detector 22 are respectively located on both sides of the center of the electrode body 1; the LED light source 21 and the detector 22 are arranged in different positions, so that light emitted by the light source irradiates the cerebral cortex, is reflected after traveling for a certain distance and can be just received by the detector 22, edge light signals emitted by the LED light source 21 are also prevented from being directly collected by the detector 22, and the measuring result of the detector 22 is prevented from being directly influenced by the light signals.
In certain preferred embodiments, the electrode assembly 3 comprises more than two circumferentially equidistant arrays of electrode probes; the electrode probes in the circumferential array can ensure the uniformity and accuracy of electroencephalogram signal acquisition; in addition, the arrangement of two or more electrode probes allows the reflected light signal scattered outward to be reflected multiple times in the multiple electrode probe and absorbed and attenuated by the electrode assembly 3.
In some preferred embodiments, the two adjacent electrode probes are disposed in a staggered manner, that is, as shown in fig. 2 and 3, the two electrode probes arranged in a circle are staggered with each other, so that the reflected light signal scattered outwards is blocked, and the reflected light signal entering from the gap between the electrode probes is attenuated by multiple reflections in the electrode probes in the outer layer, which can effectively prevent the reflected light signal from scattering outside the electrode assembly 3.
In certain preferred embodiments, the electrode probes are distributed in a two-fold circumferentially equidistant array of 20 electrode probes per fold.
In some preferred embodiments, the electrode body 1 is cylindrical and flat, and the axis line of the electrode body 1 coincides with the electrode probe array axis, so that the electrode probes are arranged along the circumference of the electrode body 1; when the brain electrode of the embodiment of the application is installed on the head of a human body, the installation position of the electrode probe with the circular edge at the periphery of the electrode body 1 can be grabbed, the head hair can be quickly pulled away by using the electrode probe through controlling the electrode body 1, and then the electrode probe can be fixed by applying pressure to the edge of the back side of the electrode body 1.
In certain preferred embodiments, the electrode probe is one of cylindrical, frustoconical, or conical; in this embodiment, the electrode probe is preferably in the shape of a circular truncated cone, which is advantageous for the electrode probe to pull open hairs.
In some preferred embodiments, the electrode probe is a microneedle electrode, most microneedle matrix electrodes are based on the MEMS technology, only the skin stratum corneum needs to be punctured when the electrode probe is used, bleeding is not caused, the electrode probe has the characteristics of low impedance and no displacement, and electroencephalogram signals of the head can be accurately acquired; in the embodiment of the application, after the hair is pulled open by the micro-needle electrode, the back side edge of the electrode body 1 can be pressed to enable the micro-needle electrode to penetrate into the skin of the head, and the micro-needle electrode has the characteristic of convenience in use.
In some preferred embodiments, the axial line of the electrode probe is perpendicular to the end face of the electrode probe connected with the electrode body 1, so that the connection and fixation of the electrode probe are facilitated, and the electrode probe can be ensured to be attached to the skin of the head.
When the microneedle motor is in a cylindrical or round table shape, the top end of the microneedle motor is provided with a corner contact end for piercing the skin cuticle.
In some preferred embodiments, the electrode body 1 is provided with a groove 11 in the middle for mounting the photoelectric sensor 2, and the electrode assembly 3 is located outside the groove 11; the installation of the photoelectric sensor 2 by the groove 11 can ensure that the light signal has sufficient irradiation and reflection distance and the generated reflected light signal can be acquired by the detector 22 of the photoelectric sensor 2, and on the other hand, the light signal horizontally emitted from the LED light source 21 can be blocked by the edge of the groove 11, thereby further preventing the light signal from scattering from the electrode assembly 3.
More specifically, when the brain electrode of the embodiment of the present application is used, the electrode body 1 is attached to the head of the human body and is used in a bending manner, therefore, the groove 11 is also in a bending state, the LED light source 21 is mounted based on the fixed circuit board 23, and part of the LED light source emits light signals towards the groove 11 and is reflected to the head of the human body after being refracted by the groove 11, so that the light signals are converged, the detector 22 can obtain more reflected light signals related to blood flow signals, and the detection accuracy is improved.
In summary, the photoelectric fusion brain electrode provided by the embodiment of the application can simultaneously acquire the scalp blood flow signal and the brain electrical signal at the same acquisition point, is convenient for observing the synchronous change of the two signals at the acquisition point, can obtain a large amount of human physiological information through analysis, provides important basis for diagnosis and prevention of diseases, brain function research and the like, and is beneficial to multi-channel brain electrical health monitoring and analysis; in addition, when the electro-optical fusion type brain electrode is used, hairs can be pulled away through the electrode assembly 3, the problem that the detection accuracy of the photoelectric sensor 2 is affected due to the fact that signal absorption is weakened due to the hairs is solved, the electrode assembly 3 arranged around the photoelectric sensor 2 can block optical signals which are emitted by the photoelectric sensor 2 and are scattered outwards, and the optical signals are prevented from being scattered into the nearby electro-optical fusion type brain electrode to affect the detection result of the nearby electro-optical fusion type brain electrode.
It is to be understood that the invention is not limited to the examples described above, but that modifications and variations may be effected thereto by those of ordinary skill in the art in light of the foregoing description, and that all such modifications and variations are intended to be within the scope of the invention as defined by the appended claims.
Claims (10)
1. The photoelectric fusion type brain electrode is characterized by comprising an electrode body (1), wherein a photoelectric sensor (2) which is located in the middle of the electrode body (1) and is based on photoplethysmography is arranged on the electrode body (1), and an electrode assembly (3) which surrounds the outer side of the photoelectric sensor (2) is further arranged on the electrode body (1).
2. The electro-optical fusion brain electrode according to claim 1, wherein the photoelectric sensor (2) comprises a plurality of LED light sources (21) for emitting light signals and a detector (22) arranged at one side of the LED light sources (21) for receiving reflected light signals.
3. The electro-optical fusion brain electrode according to claim 2, wherein the number of the LED light sources (21) is three, and the LED light sources emit green light, red light and infrared light, respectively.
4. The electro-optical fusion brain electrode according to claim 2, wherein the LED light source (21) and the detector (22) are respectively located at both sides of the center of the electrode body (1).
5. The electrofusion brain electrode according to claim 1 characterised in that the electrode assembly (3) comprises more than two circumferentially equidistant arrays of electrode probes.
6. The electro-optical fusion brain electrode according to claim 5, wherein the electrode probes adjacent to the two pairs are disposed offset from each other.
7. The electro-optical fusion brain electrode according to claim 5, wherein the electrode body (1) has a cylindrical shape, and the axis thereof coincides with the electrode probe array axis.
8. The electro-optical fusion brain electrode according to claim 5, wherein the electrode probe has one of a cylindrical shape, a truncated cone shape, and a conical shape.
9. The optoelectrofusion brain electrode according to any of claims 5-8 wherein the electrode probe is a microneedle electrode.
10. The electro-optical fusion brain electrode according to claim 1, wherein the electrode body (1) is provided with a groove (11) at the middle for mounting the photoelectric sensor (2), and the electrode assembly (3) is located outside the groove (11).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115919279A (en) * | 2023-01-13 | 2023-04-07 | 中国医学科学院北京协和医院 | Non-invasive cerebral blood flow monitoring device and method based on photoplethysmography technology |
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| CN107307870A (en) * | 2017-05-24 | 2017-11-03 | 丹阳慧创医疗设备有限公司 | A kind of driving condition brain monitoring system and method based near infrared spectrum |
| CN108309288A (en) * | 2018-02-01 | 2018-07-24 | 深圳市禹欣鑫电子有限公司 | Intelligent wearable device is monitored based on the sleep apnea of brain electricity and heart rate |
| CN112401881A (en) * | 2020-10-27 | 2021-02-26 | 北京航空航天大学 | Wearable fNIRS brain imaging system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115919279A (en) * | 2023-01-13 | 2023-04-07 | 中国医学科学院北京协和医院 | Non-invasive cerebral blood flow monitoring device and method based on photoplethysmography technology |
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