CN113058144A - Nasal cavity circulation drug administration device - Google Patents
Nasal cavity circulation drug administration device Download PDFInfo
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- CN113058144A CN113058144A CN202110520133.1A CN202110520133A CN113058144A CN 113058144 A CN113058144 A CN 113058144A CN 202110520133 A CN202110520133 A CN 202110520133A CN 113058144 A CN113058144 A CN 113058144A
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- 210000003928 nasal cavity Anatomy 0.000 title claims abstract description 54
- 238000001647 drug administration Methods 0.000 title claims description 18
- 239000007788 liquid Substances 0.000 claims abstract description 103
- 210000003128 head Anatomy 0.000 claims abstract description 69
- 239000007921 spray Substances 0.000 claims abstract description 32
- 239000011550 stock solution Substances 0.000 claims abstract description 32
- 239000003814 drug Substances 0.000 claims abstract description 26
- 238000012377 drug delivery Methods 0.000 claims abstract description 21
- 238000001802 infusion Methods 0.000 claims abstract description 18
- 239000000243 solution Substances 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 7
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 238000001914 filtration Methods 0.000 abstract description 4
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- 210000001331 nose Anatomy 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000009513 drug distribution Methods 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000000492 nasalseptum Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a nasal cavity circulation drug delivery device, which comprises a shell, a liquid storage tank, a drug delivery mechanism and a circulation mechanism, wherein the liquid storage tank is arranged in the shell; a stock solution storage cavity and a return solution storage cavity are formed in the liquid storage tank in a separated mode, and a one-way valve is arranged between the stock solution storage cavity and the return solution storage cavity; the dosing mechanism comprises a dosing spray head, a dosing pump, a first infusion pipeline and a second infusion pipeline, and liquid in the stock solution storage cavity is pumped to the dosing spray head by the dosing pump; the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline and a second liquid return pipeline, and liquid sucked by the suction head is pumped to the liquid return storage cavity by the circulating pump; the liquid returning storage cavity is internally provided with a filtering component, and the liquid sucked by the suction head flows back to the original liquid storage cavity from the liquid returning storage cavity through the one-way valve after being filtered by the filtering component. According to the technical scheme provided by the invention, the effective staying time and distribution space of the liquid medicine in the nasal cavity are prolonged through circulating administration, the medicine absorption is facilitated, and the nasal cavity is effectively prevented from being damaged by water choking and water pressure.
Description
Technical Field
The invention relates to the technical field of medical treatment and health, in particular to a nasal cavity circulating administration device.
Background
At present, the nasal administration has achieved a consensus in the medical field that the benefits of drug absorption through the nasal mucosa are limited by the nasal structure and the functionality of the administration system, and the absorption utilization rate and drug distribution capacity of the nasal administration are not high.
Disclosure of Invention
The invention aims to improve the absorption utilization rate and the drug distribution capability of nasal administration.
The invention aims to achieve the aim, and provides a nasal cavity circulation drug administration device which comprises a shell, a liquid storage tank, a drug administration mechanism and a circulation mechanism, wherein the liquid storage tank, the drug administration mechanism and the circulation mechanism are mounted on the shell;
the liquid storage tank is internally divided into a stock solution storage cavity and a return solution storage cavity, a one-way valve is arranged between the stock solution storage cavity and the return solution storage cavity, and the one-way valve is set in a way that liquid medicine in the return solution storage cavity can flow to the stock solution storage cavity;
the administration mechanism comprises an administration spray head, an administration pump, a first infusion pipeline connected between the stock solution storage cavity and the administration pump, and a second infusion pipeline connected between the administration pump and the administration spray head, wherein liquid in the stock solution storage cavity can be pumped to the administration spray head by the administration pump to be sprayed out;
the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline connected between the suction head and the circulating pump, and a second liquid return pipeline connected between the liquid return storage cavity and the circulating pump, and liquid sucked by the suction head is pumped to the liquid return storage cavity through the circulating pump;
the liquid pumped by the suction head flows back to the original liquid storage cavity from the liquid return storage cavity through the one-way valve after being filtered by the filter component.
Preferably, the side wall of the stock solution storage cavity is provided with an exhaust valve for keeping the internal and external air pressure balance of the stock solution storage cavity.
Preferably, the administration spray head and the suction head are fixed relative to the housing, and the administration spray head and the suction head are arranged such that when the administration spray head is inserted into one nostril of a human body, the suction head can be inserted into the other nostril.
Preferably, the upper end of the shell is provided with a first connector and a second connector, and the lower end of the shell is provided with a first opening and a second opening;
the administration spray head is arranged at the first interface, the suction head is arranged at the second interface, and the administration pump and the circulating pump are arranged in the cavity of the shell;
the liquid reserve tank detachably install the below of casing, just the liquid reserve tank have with stoste stores the chamber intercommunication and corresponds to the first opening of first trompil and with return the liquid and store the chamber intercommunication and correspond to the second opening of second trompil.
Preferably, the administration pump of the administration mechanism is mounted in the shell, and the administration spray head is connected to one end of the second infusion pipeline extending out of the shell, wherein at least part of the second infusion pipeline positioned outside the shell is flexible so that the administration spray head can move relative to the shell; and/or the presence of a gas in the gas,
the circulating pump of the circulating mechanism is installed in the shell, the suction head is connected to one end, located on the outer side of the shell, of the first liquid return pipeline, and at least part of pipeline, located on the outer side of the shell, of the first liquid return pipeline is flexible so that the suction head can move relative to the shell.
Preferably, the device further comprises a connection part arranged to be connected to the head or ear when the administration spray head and/or the suction head is inserted into the nasal cavity, so as to prevent the administration spray head and/or the suction head from being removed from the nasal cavity.
Preferably, the nasal cavity circulation drug administration device further comprises a control unit connected with the drug administration pump and the circulation pump, and a control switch connected with the control unit;
the control unit is set to start the circulating pump and the dosing pump simultaneously when the control switch is started; and
the control unit is set to stop the administration pump firstly when the control switch is turned off, and stop the suction pump after the suction pump continues to work for a preset time; or, the control switch has a first off state and a second off state, the control unit is configured such that when the control switch is in the first off state, the administration pump stops working, and the suction pump continues working, and when the control switch is in the second off state, both the administration pump and the suction pump stop working.
Preferably, the administration pump and the circulation pump are both micro-diaphragm pumps.
Preferably, the nasal circulation drug delivery device further comprises a first cover body covering the drug delivery nozzle and a second cover body covering the suction head.
The technical scheme provided by the invention can realize the nasal cavity circulation administration, thereby improving the effective retention time and distribution space of the liquid medicine in the nasal cavity and being beneficial to the absorption and utilization rate of the medicine. When the nasal cavity to one side is circulated and is dosed, the nasal cavity to the other side is sucked to generate negative pressure traction, so that the problem that the nasal cavity is choked by water and the water pressure in the nasal cavity causes damage to the nasal cavity when the nasal cavity is dosed in the prior art can be effectively avoided.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate an embodiment of the invention and, together with the description, serve to explain the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic structural view of a device for administration of drug by nasal circulation according to an embodiment of the present invention;
FIG. 2 is a schematic view of the nasal circulation delivery device from another perspective;
FIG. 3 is a schematic view of the internal structure of the nasal circulation drug delivery device;
FIG. 4 is a schematic view of the power cord being plugged into the nasal circulation drug delivery device;
FIG. 5 is a schematic electrical circuit diagram of the nasal circulation delivery device;
FIG. 6 is a schematic view of the liquid storage tank being removed from the housing and then the chemical solution being injected into the stock solution storage chamber;
FIG. 7 is a schematic view of the waste water being dumped from the return storage chamber after the tank is removed from the housing;
FIG. 8 is a schematic view of the structure of a human nose;
FIG. 9 is another structural schematic of a human nose;
FIG. 10 is a schematic view of the nasal cavity being cleaned using a device for the cyclical administration of medication through the nasal cavity according to one embodiment;
fig. 11 is a schematic view of nasal cavity cleaning using another embodiment of the provided device for nasal circulation.
Description of the reference numerals
1-a dosing mechanism; 11-administration spray head; 12-a dosing pump; 13-a first infusion line; 14-a second infusion line; 2-a circulation mechanism; 21-a suction head; 22-a circulation pump; 23-a first liquid return line; 24-a second return line; 3-a shell; 31 — a first interface; 32-a second interface; 33-a first opening; 34-a second opening; 35-a first seal; 36-a second seal; 4-a liquid storage tank; 41-stock solution storage cavity; 42-a liquid return storage cavity; 43-a one-way valve; 44-a filter element; 45-exhaust valve; 5-control switch; 51-switching on and off the display lamp; 6-a battery; 7-a first cover; 8-a second cover body; 9-a circuit board; 10-a charging interface; 20-a power line; 30-a connecting member; 100-a head; 101-nose; 102-nasal septum; 103-a first nostril; 104-first nasal passage; 105-a second nostril; 106-second nasal passage; 107-posterior nares.
Detailed Description
Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many different forms and should not be construed as limited to the examples set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The drawings are merely schematic illustrations of the present disclosure and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and thus their repetitive description will be omitted.
Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. In the following description, numerous specific details are provided to give a thorough understanding of embodiments of the disclosure. One skilled in the relevant art will recognize, however, that the subject matter of the present disclosure can be practiced without one or more of the specific details, or with other methods, components, devices, steps, and the like. In other instances, well-known structures, methods, devices, implementations, materials, or operations are not shown or described in detail to avoid obscuring aspects of the disclosure.
Spatially relative terms, such as "upper," "lower," "left," "right," and the like, may be used herein for ease of description to describe one element or feature's relationship to another element or feature as illustrated in the figures. It will be understood that the spatial terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" other elements or features would then be oriented "above" the other elements or features. Thus, the exemplary term "lower" can encompass both an upper and a lower orientation. The device may also be otherwise oriented, such as by rotation through 90 degrees or at other orientations and the spatially relative descriptors used herein interpreted accordingly.
The invention provides a nasal cavity circulation drug administration device, as shown in figures 1-4, the nasal cavity circulation drug administration device comprises a shell 3, a liquid storage tank 4, a drug administration mechanism 1 and a circulation mechanism 2, wherein the liquid storage tank 4, the drug administration mechanism 1 and the circulation mechanism 2 are arranged on the shell 3;
a stock solution storage cavity 41 and a return solution storage cavity 42 are formed in the liquid storage tank 4 in a separated manner, a check valve 43 is arranged between the stock solution storage cavity 41 and the return solution storage cavity 42, and the check valve 43 is set such that the liquid medicine in the return solution storage cavity 42 can only flow to the stock solution storage cavity 41;
the administration mechanism 1 comprises an administration spray head 11, an administration pump 12, a first infusion pipeline 13 connected between the stock solution storage cavity 41 and the administration pump 12, and a second infusion pipeline 14 connected between the administration pump 12 and the administration spray head 11, wherein the liquid in the stock solution storage cavity 31 can be pumped to the administration spray head 11 by the administration pump 12 to be sprayed out;
the circulating mechanism 2 comprises a suction head 21, a circulating pump 22, a first liquid return pipeline 23 connected between the suction head 21 and the circulating pump 22, and a second liquid return pipeline 24 connected between the liquid return storage cavity 42 and the circulating pump 22, and liquid sucked by the suction head 21 is pumped to the liquid return storage cavity 42 through the circulating pump 22;
a filtering component 44 is arranged in the liquid return storage cavity 42, the liquid sucked by the suction head 21 is filtered by the filtering component 44 and then flows back to the original liquid storage cavity 41 from the liquid return storage cavity 42 through the one-way valve 43, and the liquid in the original liquid storage cavity 41 is sprayed to the nasal cavity.
Preferably, a vent valve 45 for keeping the balance of the internal and external air pressures of the stock solution storage chamber 41 is provided on the side wall of the stock solution storage chamber 41. By providing the vent valve 45, it is ensured that the liquid in the return liquid storage chamber 42 can enter the raw liquid storage chamber 41 through the check valve 43.
When the nasal cavity circulation drug administration device provided by the invention is used, the drug administration spray head 11 and the suction head 21 are respectively inserted into a nasal cavity, the medicine liquid flowing out of one nasal cavity through the suction head 21 can be sucked while the medicine administration nozzle 11 administers medicine to the other nasal cavity controllably, then the liquid medicine pumped out is filtered by the filter part 44 to filter the nasal secretion carried in the liquid medicine, the attachment is sucked in and then enters the stock solution storage cavity 41 through the one-way valve 43, then the medicine is sprayed out of the stock solution storage cavity 41 to the nasal cavity through the medicine feeding nozzle 11 again to realize the circulation medicine feeding to the nasal cavity, by means of the nasal cavity circulating administration mode, the problem that the nasal cavity is choked with water and water pressure causes damage to the nasal cavity when the nasal cavity is administered in the prior art can be solved, but also can improve the effective retention time and distribution space of the liquid medicine in the nasal cavity, and is beneficial to the absorption and utilization rate of the medicine.
The nasal circulation drug delivery device provided by the invention is explained in detail according to the specific embodiment.
First embodiment
In the first embodiment, the administration head 11 and the administration pump 12 in the administration mechanism 1 and the suction head 21 and the circulation pump 22 in the circulation mechanism 2 are fixed to the housing.
In this embodiment, the administration nozzle 11 and the suction head 21 are fixed to the housing 3, and the administration nozzle 11 and the suction head 21 are arranged such that when the administration nozzle 11 is inserted into one nostril of a human body to perform cyclic administration, the suction head 21 can be inserted into the other nostril to perform suction.
Specifically, as shown in fig. 1-3, the housing 3 of the administration device for nasal circulation has a first interface 31 and a second interface 32 at the upper end, and a first opening 33 and a second opening 34 at the lower end;
the administration spray head 11 is fixedly installed in the first interface 31, the administration pump 12 is installed in the cavity of the housing 3, the suction head 21 is fixedly installed in the second interface 32, and the circulation pump 22 is installed in the cavity of the housing 3.
As shown in fig. 3 and 4, a first sealing member 35 for sealing the connection between the first opening of the liquid storage tank 4 and the first liquid conveying pipeline 13 is disposed at the first opening 33; a second sealing element 36 is arranged at the second opening 34 for sealing the connection between the second opening of the reservoir 4 and the second return line 24.
Preferably, the reservoir 4 is arranged to be removably mounted on the housing 3. Fig. 6 shows that the liquid storage tank 4 is detached from the housing 3, and then the liquid storage tank 4 is attached to the housing 3 after being filled with the liquid chemical to be circulated into the raw liquid storage chamber 41, and fig. 7 shows that the liquid storage tank 4 is detached from the housing 3 after use, and the liquid in the liquid return storage chamber 42 is poured out.
The nasal circulation drug administration device also comprises a first cover body 7 used for covering the drug administration spray head 11 and a second cover body 8 used for covering the suction head 21. When in use, the first cover 7 and the second cover 8 are removed, and after use, the first cover 7 and the second cover 8 are covered to protect the administration spray head 11 and the suction head 21.
The battery 6 is provided in the housing 3, and as shown in fig. 3, the battery 6 may be provided at a position between the administration pump 12 and the circulation pump 22, or may be provided at another position. The housing 3 is provided with a charging interface 10 for charging the battery 6. As shown in fig. 4, the battery 6 can be charged by connecting a power supply line 20 (a power supply line of a USB interface in the present embodiment) to the charging interface 10.
In addition, the control switch 5 for controlling the nasal circulation drug delivery device is arranged at a position suitable for operation on the casing 3, and a switch indicator lamp 51 for indicating the on-off state of the control switch 5 is also arranged on the casing 3. When the control switch 5 is in the on state, the switch indicator lamp 51 is turned on, and when the control switch 5 is in the off state, the switch indicator lamp 51 is turned off.
In the present embodiment, in order to facilitate control of the administration mechanism 1 and the circulation mechanism 2, the nasal circulation administration device further includes a control unit connected to the administration pump 12 and the circulation pump 22, and a control switch 5 connected to the control unit. Wherein the control unit is embodied as a circuit board 9 shown in fig. 3 and 5. Fig. 5 shows a schematic circuit diagram of the nasal circulation drug delivery device.
The control unit is arranged such that the suction pump 22 and the administration pump 12 are activated simultaneously when the control switch 5 is activated;
in order to ensure that the medicines are sucked out of the nasal cavity by the circulating mechanism 2 after the nasal cavity circulating administration device is used, no medicine is left in the nasal cavity, namely, only the circulating mechanism 2 works after the administration mechanism 1 stops working. The control unit is configured to stop the administration pump 12 when the control switch 5 is turned off, and stop the suction pump 22 after the suction pump continues to operate for a predetermined time. Alternatively, the control switch 5 is set to have a first off state and a second off state, and the control unit is set such that when the control switch 5 is in the first off state, the administration pump 12 stops operating and the suction pump 22 continues operating, and when the control switch 5 is in the second off state, both the administration pump 12 and the suction pump 22 stop operating. This ensures that no drug remains in the nasal cavity after the administration cycle is complete and that the drug is ultimately stored in the stock solution storage tank 42.
The first off state may be a state in which the switch 5 is controlled to be turned off only once, and the second off state may be a state in which the switch 5 is controlled to be turned off twice. Of course, the first off state and the second off state may also take other forms, for example, two control switches 5 may be provided, where one control switch is in the first off state when turned off, and the other control switch is in the second off state when turned off.
Second embodiment
In this second embodiment, referring to fig. 11, the administration pump 12 of the administration mechanism 1 is installed in the housing 3, and the administration spray head 11 is connected to one end of the second infusion line 14 extending out of the housing 3, wherein at least a part of the second infusion line 14 located outside the housing 3 is flexible to enable the administration spray head 11 to move relative to the housing 3; and/or the presence of a gas in the gas,
the circulating pump 22 of the circulating mechanism 2 is installed in the housing 3, and the suction head 21 is connected to one end of the first liquid return pipeline 23 located outside the housing 3, wherein at least part of the first liquid return pipeline 23 located outside the housing 3 is flexible so that the suction head 21 can move relative to the housing 3.
The attachment of the administration pump 12 of the administration mechanism 1 and the circulation pump 22 of the circulation mechanism 2 in the housing 3 and the attachment of the liquid storage tank 4 in the present embodiment may be the same as in the above embodiment, but different from the above embodiment, the administration nozzle 11 and the suction head 21 are flexibly connected to the outside of the housing 3 so as to be movable relative to the housing 3. Thus, when the nasal circulation drug delivery device is used, the drug delivery nozzle 11 and the suction head 21 can be inserted into the nasal cavity only by holding with hands, and the device is light.
Preferably, the device further comprises a connecting part 30, wherein the connecting part 30 is configured to be connected to the head or the ear when the administration spray head 11 and/or the suction head 21 is inserted into the nasal cavity, so as to prevent the administration spray head and/or the suction head from being separated from the nasal cavity. For example, the connection member 30 may be an ear hook or a head hanging string connected to the administration nozzle and the suction head, and when the administration nozzle 11 and the suction head 21 are inserted into the nasal cavity, respectively, the administration nozzle 11 and the suction head 21 may be prevented from being separated from the nasal cavity by the ear hook or the head hanging string connected to the head, which is advantageous to free both hands.
The charging and controlling method in the second embodiment may be the same as that in the first embodiment, and will not be described herein again.
The following is a description of a specific procedure for cleaning the nasal cavity using the nasal circulation drug delivery device.
Fig. 8 and 9 show the structure of the human head 100 at the upper nose, on the bisector in the interior of the nose 101 of the head 100 there are the nasal septum 102, 2 nasal passages are respectively located at the two sides of the nasal septum 102, namely a first nasal passage 104 communicating with the first nostril 103 and a second nasal passage 106 communicating with the second nostril 105, the first nasal passage 104 and the second nasal passage 106 communicate at the posterior nostril 107 at the rear of the whole nasal cavity, and liquid can flow between the first nasal passage 104 and the second nasal passage 106 through the posterior nostril 107, so that the liquid entering from the first nostril 103 can flow out of the second nostril 105 through the first nasal passage 104, the posterior nostril 107 and the second nasal passage 106 in sequence.
Fig. 10 shows a state where the administration mechanism 1 and the circulation mechanism 2 of the nasal circulation administration device are simultaneously operated to administer the medicine to the nasal cavity, and the nasal circulation administration device shown in fig. 10 is the nasal circulation administration device provided in the first embodiment described above.
When in use, the liquid storage tank 4 is firstly arranged on the shell 3, and the first cover body 7 and the second cover body 8 are taken down to expose the administration spray head 11 and the suction head 21;
the administration nozzle 11 is inserted into the first nostril 103, and the suction head 21 is inserted into the second nostril 105;
the control switch 5 is turned on, the administration pump 12 and the circulating pump 22 are started simultaneously, the administration pump 12 pumps the liquid in the stock solution storage cavity 41 to the first nostril 103, the liquid entering the first nasal passage 104 from the first nostril 103 can enter the second nasal passage 105 from the back nostril 107, then enters the liquid return storage cavity 42 along the first liquid return pipeline 23, the circulating pump 22 and the second liquid return pipeline 24 by the suction head 21 positioned in the second nostril 105, and the liquid flowing out of the opposite nasal cavity is sucked and discharged while the nasal cavity is administered. The liquid sucked and discharged is filtered by the filter member 44, enters the stock solution storage chamber 41 through the check valve 43, and is then sent from the stock solution storage chamber 41 to the nasal cavity by the administration nozzle 11.
After the circulation of the drug is completed, the control switch 5 is turned off, at which time the operation of the drug delivery pump 12 is stopped, and the circulation pump 22 stops after continuing to pump for a certain period of time.
Fig. 11 shows a schematic view of the nasal cavity circulation drug delivery device provided by the second embodiment. The administration nozzle 11 is connected to the outside of the housing 3 through the flexible second infusion line 14 and the suction head 12 through the flexible first return line 23, and when the administration nozzle 11 and the suction head 12 are inserted into two nostrils respectively, the administration nozzle 11 and the suction head 12 are connected to the head 100 through the connecting part 30, so that the administration nozzle 11 and the suction head 12 can be prevented from being separated from the nostrils. The specific operation of the device in this embodiment is the same as that of the above embodiment.
The preferred embodiments of the present invention have been described in detail above with reference to the accompanying drawings, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, numerous simple modifications can be made to the technical solution of the invention, including combinations of the individual specific technical features in any suitable way. The invention is not described in detail in order to avoid unnecessary repetition. Such simple modifications and combinations should be considered within the scope of the present disclosure as well.
Claims (9)
1. The nasal cavity circulation drug administration device is characterized by comprising a shell, a liquid storage tank, a drug administration mechanism and a circulation mechanism, wherein the liquid storage tank, the drug administration mechanism and the circulation mechanism are mounted on the shell;
the liquid storage tank is internally divided into a stock solution storage cavity and a return solution storage cavity, a one-way valve is arranged between the stock solution storage cavity and the return solution storage cavity, and the one-way valve is set in a way that liquid medicine in the return solution storage cavity can flow to the stock solution storage cavity;
the administration mechanism comprises an administration spray head, an administration pump, a first infusion pipeline connected between the stock solution storage cavity and the administration pump, and a second infusion pipeline connected between the administration pump and the administration spray head, wherein liquid in the stock solution storage cavity can be pumped to the administration spray head by the administration pump to be sprayed out;
the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline connected between the suction head and the circulating pump, and a second liquid return pipeline connected between the liquid return storage cavity and the circulating pump, and liquid sucked by the suction head is pumped to the liquid return storage cavity through the circulating pump;
the liquid pumped by the suction head flows back to the original liquid storage cavity from the liquid return storage cavity through the one-way valve after being filtered by the filter component.
2. The device for nasal circulatory drug delivery according to claim 1, wherein the side wall of the stock solution storage chamber is provided with an exhaust valve for maintaining the balance of the internal and external air pressures of the stock solution storage chamber.
3. The device as set forth in claim 1, wherein the applicator head and the suction tip are fixed relative to the housing and are configured such that when the applicator head is inserted into one nostril of a subject, the suction tip is insertable into the other nostril.
4. The device for nasal circulatory drug delivery according to claim 3, wherein the housing is provided with a first port and a second port at an upper end thereof and a first opening and a second opening at a lower end thereof;
the administration spray head is arranged at the first interface, the suction head is arranged at the second interface, and the administration pump and the circulating pump are arranged in the cavity of the shell;
the liquid reserve tank detachably install the below of casing, just the liquid reserve tank have with stoste stores the chamber intercommunication and corresponds to the first opening of first trompil and with return the liquid and store the chamber intercommunication and correspond to the second opening of second trompil.
5. The device as claimed in claim 1, wherein the drug delivery pump of the drug delivery mechanism is mounted in the housing, and the drug delivery nozzle is connected to an end of the second infusion line extending outside the housing, wherein at least a portion of the second infusion line outside the housing is flexible to allow the drug delivery nozzle to move relative to the housing; and/or the presence of a gas in the gas,
the circulating pump of the circulating mechanism is installed in the shell, the suction head is connected to one end, located on the outer side of the shell, of the first liquid return pipeline, and at least part of pipeline, located on the outer side of the shell, of the first liquid return pipeline is flexible so that the suction head can move relative to the shell.
6. The device according to claim 5, further comprising a connection part configured to be connected to the head or ear when the administration spray head and/or the suction head is inserted into the nasal cavity, so as to prevent the administration spray head and/or the suction head from being detached from the nasal cavity.
7. The administration device according to any one of claims 1 to 6, further comprising a control unit connected to the administration pump and the circulation pump, and a control switch connected to the control unit;
the control unit is set to start the circulating pump and the dosing pump simultaneously when the control switch is started; and
the control unit is set to stop the administration pump firstly when the control switch is turned off, and stop the suction pump after the suction pump continues to work for a preset time; or, the control switch has a first off state and a second off state, the control unit is configured such that when the control switch is in the first off state, the administration pump stops working, and the suction pump continues working, and when the control switch is in the second off state, both the administration pump and the suction pump stop working.
8. A device according to any one of claims 1 to 6, wherein both the dosing pump and the circulation pump are miniature diaphragm pumps.
9. The device for nasal circulatory drug delivery according to any one of claims 1-6, wherein the device further comprises a first cap for covering the delivery nozzle and a second cap for covering the suction head.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110520133.1A CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110520133.1A CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113058144A true CN113058144A (en) | 2021-07-02 |
| CN113058144B CN113058144B (en) | 2024-01-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN202110520133.1A Active CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
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| CN113730779A (en) * | 2021-11-05 | 2021-12-03 | 纳索菲德(上海)制药技术有限公司 | Device for spraying medicine to nasal cavity and using method |
| CN114470496A (en) * | 2022-01-14 | 2022-05-13 | 赵子逸 | Nasal olfactory region circulating administration device and application method thereof |
| CN115282412A (en) * | 2022-01-14 | 2022-11-04 | 温州医科大学 | Drug delivery device entering blood circulation through nasal cavity and application method thereof |
| CN116898717A (en) * | 2023-09-13 | 2023-10-20 | 暨甄(北京)科技有限公司 | Nasal cavity nursing device |
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| CN113058144B (en) | 2024-01-26 |
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Effective date of registration: 20220928 Address after: 550003 in the standard plant park in the south area of high end equipment manufacturing industrial park, Gui'an New District, Guiyang City, Guizhou Province Applicant after: Guizhou happy Biotechnology Co.,Ltd. Applicant after: Joy (Beijing) Medical Technology Co.,Ltd. Address before: 100039 2-1505, yard 18, Wanfeng Road, Haidian District, Beijing Applicant before: Huang Haibing |
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