CN113048687A - Reagent refrigeration device for analyzer and working method thereof - Google Patents
Reagent refrigeration device for analyzer and working method thereof Download PDFInfo
- Publication number
- CN113048687A CN113048687A CN202110366998.7A CN202110366998A CN113048687A CN 113048687 A CN113048687 A CN 113048687A CN 202110366998 A CN202110366998 A CN 202110366998A CN 113048687 A CN113048687 A CN 113048687A
- Authority
- CN
- China
- Prior art keywords
- reagent
- cavity
- storage cavity
- pipe
- air
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 96
- 238000000034 method Methods 0.000 title claims abstract description 14
- 238000005057 refrigeration Methods 0.000 title claims description 27
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 40
- 239000007788 liquid Substances 0.000 claims abstract description 36
- 238000007789 sealing Methods 0.000 claims abstract description 24
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 20
- 238000002156 mixing Methods 0.000 claims abstract description 16
- 238000004321 preservation Methods 0.000 claims abstract description 10
- 238000001514 detection method Methods 0.000 claims abstract description 8
- 238000009434 installation Methods 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- 238000010521 absorption reaction Methods 0.000 claims description 26
- 239000000919 ceramic Substances 0.000 claims description 15
- 230000001105 regulatory effect Effects 0.000 claims description 12
- 229920000742 Cotton Polymers 0.000 claims description 8
- 239000003595 mist Substances 0.000 claims description 8
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 6
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 6
- 241001330002 Bambuseae Species 0.000 claims description 6
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 6
- 239000011425 bamboo Substances 0.000 claims description 6
- 229910010293 ceramic material Inorganic materials 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 239000011888 foil Substances 0.000 claims description 6
- 238000004378 air conditioning Methods 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 230000009467 reduction Effects 0.000 claims description 4
- 238000004458 analytical method Methods 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims description 3
- 241000196324 Embryophyta Species 0.000 claims description 2
- 230000009471 action Effects 0.000 claims description 2
- 238000009413 insulation Methods 0.000 description 15
- 238000004891 communication Methods 0.000 description 11
- 239000011324 bead Substances 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 229920002943 EPDM rubber Polymers 0.000 description 5
- 239000010425 asbestos Substances 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 229910052895 riebeckite Inorganic materials 0.000 description 4
- 238000005070 sampling Methods 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000011435 rock Substances 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000002038 chemiluminescence detection Methods 0.000 description 1
- 238000005034 decoration Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D11/00—Self-contained movable devices, e.g. domestic refrigerators
- F25D11/003—Transport containers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/06—Walls
- F25D23/065—Details
- F25D23/066—Liners
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2201/00—Insulation
- F25D2201/10—Insulation with respect to heat
- F25D2201/12—Insulation with respect to heat using an insulating packing material
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention provides a reagent refrigerating device for an analyzer and a working method thereof, belonging to the technical field of detection of the analyzer, the reagent refrigerating device for the analyzer comprises a refrigerating box, a refrigerating assembly and a uniformly mixing assembly, wherein the refrigerating box comprises a shell and a sealing cover, the sealing cover is rotatably connected with the shell, the interior of the shell comprises a reagent storage cavity, a cold air circulation channel, a vacuum cavity and a heat preservation shell which are sequentially arranged from inside to outside, the interior of the sealing cover comprises a liquid nitrogen storage cavity, a refrigerating cavity and a liquid storage cavity which are sequentially and transversely arranged, one side opposite to the liquid nitrogen storage cavity is provided with an installation cavity, the liquid nitrogen storage cavity is communicated with a discharge pipe, one end of the discharge pipe is connected with an adjusting valve, the output end of the adjusting valve is connected with a conveying pipe, a sample reagent bottle is placed in a container, and a crank block is driven, the connecting rod drives the supporting column to drive the rotating piece to shake at multiple angles by taking the rotating piece as an axis, and the sample reagent can be uniformly mixed.
Description
Technical Field
The invention belongs to the technical field of biochemical detection, and particularly relates to a reagent refrigerating device for an analyzer and a working method thereof.
Background
The reagent refrigerating device is widely applied to in vitro diagnostic equipment, such as a full-automatic biochemical analyzer, a chemiluminescence immunoassay analyzer, a gene sequencer, a blood cell analyzer and the like. In vitro diagnostic devices have special requirements for the refrigerated environment of reagents or samples, for example, the refrigerated environment temperature is 2 ℃ to 8 ℃.
In many automated detection instruments, such as chemiluminescence detection instruments or electrochemical analyzers, special reagent refrigeration devices are required to provide functions of refrigerating, mixing, and scheduling reagents. The reagent put into the reagent bin needs to be refrigerated, the reagent can be transferred to a designated position, and meanwhile, part of the reagent (such as magnetic bead liquid, including buffer solution and magnetic beads, whether the magnetic beads and the buffer solution are uniformly mixed or not plays an important role in a detection result, and the magnetic beads are settled to the bottom after the magnetic bead liquid is static for a long time, so that the magnetic bead liquid needs to be uniformly mixed before the magnetic bead liquid is used).
Current cold storage plant, its structure is comparatively complicated, and bulky, and the operating personnel of being not convenient for carry, consequently makes the transportation of the sample reagent of being not convenient for to, its heat preservation effect is relatively poor, hardly satisfies practical application.
Disclosure of Invention
The embodiment of the invention provides a reagent refrigerating device for an analyzer and a working method thereof, and aims to solve the problems that the existing refrigerating device is complex in structure, large in size, inconvenient to carry and relatively poor in heat preservation effect.
In view of the above problems, the technical solution proposed by the present invention is:
the present invention provides a reagent refrigeration device for an analysis instrument, comprising:
the refrigerator comprises a shell and a sealing cover, wherein the sealing cover is rotatably connected with the shell, the inside of the shell comprises a reagent storage cavity, an air conditioning circulation channel, a vacuum cavity and a heat preservation shell which are sequentially arranged from inside to outside, the inside of the sealing cover comprises a liquid nitrogen storage cavity, a refrigeration cavity and a liquid storage cavity which are sequentially and transversely arranged, an installation cavity is arranged on one side opposite to the liquid nitrogen storage cavity, the liquid nitrogen storage cavity is communicated with a discharge pipe, one end of the discharge pipe is connected with a regulating valve, the output end of the regulating valve is connected with a conveying pipe, a pressure sensor is installed on the conveying pipe, one end of the conveying pipe extends to the inside of the refrigeration cavity, one end of the conveying pipe, which is positioned in the refrigeration cavity, is sleeved with a heat absorption bag, a booster pump is arranged inside the installation cavity, and the, one end of the pressure increasing pipe is communicated with the conveying pipe;
the refrigeration component comprises a compressor, a condenser and a T-shaped cylinder, the output end and the input end of the compressor are respectively connected with a first communicating pipe and a second communicating pipe, one end of the second communicating pipe passes through the through hole of the refrigeration cavity and extends into the reagent storage cavity, and is communicated with the cold air circulation channel, one end of the first communicating pipe is connected with the input end of the condenser, the output end of the condenser is connected with a third communicating pipe, one end of the third communicating pipe passes through the through hole of the refrigerating cavity and extends into the reagent storage cavity, and with air conditioning circulation passageway intercommunication, a T shape section of thick bamboo sets up the inside in refrigeration chamber, just the one end of a T shape section of thick bamboo extends to inside, the other end in liquid storage chamber pass through the humidifying pipe with third communicating pipe intercommunication, the inside of a T shape section of thick bamboo transversely has set gradually cotton stick and the pottery atomizing piece of absorbing water.
As a preferable technical scheme of the invention, the heat-insulating shell comprises a first filling layer, a second filling layer, a heat-insulating layer, a first heat-insulating layer, a second heat-insulating layer and a decorative layer which are sequentially arranged from inside to outside.
As a preferred technical solution of the present invention, the first heat insulation layer is made of a purlin board, the second heat insulation layer is made of a ceramic material, and the decorative layer is made of a decorative foil.
As a preferable technical scheme of the invention, the shell is rotatably connected with a handle.
As a preferable technical solution of the present invention, a temperature controller is installed at one side of the housing.
In a preferred embodiment of the present invention, the sealing cover and the housing are opened and closed by a pressing fastener.
As a preferable technical solution of the present invention, a heat radiation window is provided at the top of the sealing cover.
As a preferred technical scheme of the invention, the reagent storage device further comprises a blending component, the blending component comprises two supporting seats, two rotating parts, a supporting column, a small motor and a rotary table, the two supporting seats and the small motor are fixedly connected to one side of the bottom of the reagent storage cavity, the small motor is positioned between the two supporting seats, the rotating part is rotatably connected between the two supporting seats, the rotating part is connected with the supporting column, one end of the supporting column is fixedly connected with a first supporting plate, the rotary table is arranged above the first supporting plate, a second supporting plate is arranged above the rotary table, the second supporting plate, the rotary table and the first supporting plate are fixed through bolts, the other end of the supporting column is connected with a connecting rod, and the output end of the small motor is sleeved with a fixed sleeve, the surface of the fixed sleeve is fixedly connected with a bent block, and the top of the bent block is fixedly connected with one end of the connecting rod;
the rotating part comprises a rectangular frame, auxiliary plates, a first rotating shaft and a second rotating shaft, the auxiliary plates are arranged on the long side frame and the short side frame of the rectangular frame, the first rotating shaft is fixedly connected between the auxiliary plates on the long side frame of the rectangular frame, the first rotating shaft is rotatably connected with the supporting column, the second rotating shaft is fixedly connected to one side of the auxiliary plates on the short side frame of the rectangular frame, and one end of the second rotating shaft is rotatably connected with the supporting seat.
As a preferable technical scheme of the invention, a plurality of containers are distributed on the turntable in a surrounding manner, and magnets are arranged on one sides of the bottoms of the containers.
In another aspect, the present invention provides a method of operating a reagent refrigeration apparatus for an analyzer, comprising the steps of:
s1, mixing sample reagents: after the sample is collected, placing a sample reagent bottle in a container, and electrifying a small motor to drive a crank block to rotate, so that a connecting rod drives a supporting column to drive a multi-angle swing by taking a rotating piece as an axis, and the sample reagent can be uniformly mixed;
s2, cold storage and preservation: on the way of the back-carrying detection, the storage temperature is adjusted through the temperature controller, at the moment, the temperature controller controls the compressor to compress air and conveys the air to the condenser through the first communicating pipe, after the temperature reduction treatment of the condenser, cold air can be conveyed to the cold air circulation channel through the second communicating pipe, the temperature is increased after heat exchange is carried out on hot air in the absorption reagent storage cavity, and the air is compressed again through the compressor to complete air circulation;
s3, cooling the refrigerating cavity: when the condenser exchanges heat with high-temperature air compressed by the compressor, the regulating valve is controlled to be powered on and opened by the temperature controller, the liquid nitrogen storage cavity is conveyed into the heat absorption bag through the conveying pipe, the heat absorption bag is raised under the action of pressure, strong cold air is formed in the heat absorption bag, and the high-temperature air discharged by the condenser can be absorbed;
s4, cool air humidification: in the air circulation process, the moisture in the inner part of the liquid storage cavity is absorbed to one side of the ceramic atomizing sheet through the water absorption cotton rod, the temperature controller enables the ceramic atomizing sheet to oscillate at high frequency through current, the moisture is thrown away from a small hole of the ceramic atomizing sheet to form water mist, the water mist is conveyed into the third conveying pipe through the atomizing pipe to humidify cold air, and water drops are attached to the wall surface of the cold air circulation channel to continuously absorb heat.
Compared with the prior art, the invention has the beneficial effects that:
(1) the refrigerator with small volume is matched with the handle for use, so that the refrigerator is favorable for carrying, and the sampling efficiency is improved.
(2) The vacuum cavity is utilized to form an isolation barrier for the shell, so that air flow is reduced, the reagent storage cavity of the shell is kept at a low temperature continuously, and the reagent can be effectively stored at a low temperature.
(3) The first heat insulation layer is made of a Prun board, the second heat insulation layer is made of a ceramic material, the decorative layer is made of decorative foil, and the first filling layer and the second filling layer are respectively made of an EPDM (ethylene-propylene-diene monomer) board and an asbestos material; the EPDM sheet material and the asbestos material have strong heat insulation property, so that the heat insulation performance of the shell is enhanced; in addition, the Pren board, the ceramic material and the decorative foil have strong heat insulation property, so that the heat insulation performance of the shell is enhanced, and the endothermic reaction between cold air in the reagent storage cavity and external high-temperature air is avoided.
(4) Adjust storage temperature through temperature controller, at this moment, temperature controller control compressor compressed air to carry to the condenser through first communicating pipe, after the cooling processing through the condenser, during cold air accessible second communicates pipe and carries to air conditioning circulation passageway, heats after carrying out the heat exchange through the inside hot-air of absorption reagent storage chamber, compresses once more through the compressor and accomplishes air cycle.
(5) Place sample reagent bottle in the container, through the rotatory bent piece of small-size motor circular telegram drive, make the connecting rod drive the support column and use the rotation piece to drive the multi-angle and rock as the axle center, can be with sample reagent mixing.
The foregoing description is only an overview of the technical solutions of the present invention, and the embodiments of the present invention are described below in order to make the technical means of the present invention more clearly understood and to make the above and other objects, features, and advantages of the present invention more clearly understandable.
Drawings
FIG. 1 is a perspective view of a reagent cooler for an analyzer according to the present invention;
FIG. 2 is a left side view of the reagent cooler for an analytical instrument according to the present disclosure;
FIG. 3 is a sectional top view of a sealing cover of the reagent refrigerating apparatus for an analyzer according to the present invention;
FIG. 4 is a front sectional view of a housing of the reagent cooler for an analyzer according to the present invention;
FIG. 5 is a schematic view of the structure of the heat-insulating case of the reagent refrigerating apparatus for an analyzer according to the present invention;
FIG. 6 is a schematic diagram of a mixing assembly of the reagent refrigerating apparatus for an analyzer according to the present invention;
FIG. 7 is a top view of a rotor of the reagent cooler for an analyzer according to the present invention;
FIG. 8 is a cross-sectional view of a container of the reagent cooler for an analyzer disclosed herein;
FIG. 9 is a communication connection diagram of a reagent cooler for an analyzer according to the present disclosure;
fig. 10 is a flowchart illustrating an operation of the reagent refrigerating apparatus for an analyzer according to the present invention.
Description of reference numerals: 100-refrigerating box, 110-shell, 111-reagent storage cavity, 112-cold air circulation channel, 113-vacuum cavity, 114-heat preservation shell, 1141-first filling layer, 1142-second filling layer, 1143-heat preservation layer, 1144-first heat insulation layer, 1145-second heat insulation layer, 1146-decoration layer, 115-handle, 116-temperature controller, 117-negative pressure pump, 1171-negative pressure pipe, 118-discharge port, 120-sealing cover, 121-liquid nitrogen storage cavity, 1211-installation cavity, 1212-regulating valve, 1213-conveying pipe, 1214-pressure sensor, 1215-heat absorption bag, 1216-booster pump, 1217-booster pipe, 122-refrigerating cavity, 123-liquid storage cavity, 124-pressing fastener, 125-heat dissipation window, 200-refrigeration component, 210-compressor, 211-first communicating pipe, 212-second communicating pipe, 220-condenser, 221-third communicating pipe, 230-T-shaped cylinder, 231-absorbent cotton rod, 232-ceramic atomization sheet, 233-humidifying pipe, 300-blending component, 310-supporting seat, 320-rotating component, 321-rectangular frame, 322-auxiliary plate, 323-first rotating shaft, 324-second rotating shaft, 330-supporting column, 331-first supporting plate, 332-second supporting plate, 333-connecting rod, 340-small motor, 341-fixing sleeve, 342-curved block, 350-rotating disk, 360-container and 361-magnet.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Example one
Referring to the attached drawings 1-9, the invention provides a technical scheme: the reagent refrigerating device for the analytical instrument comprises a refrigerating box 100, a refrigerating assembly 200 and a blending assembly 300;
referring to fig. 1 to 3, the refrigerator 100 includes a casing 110 and a sealing cover 120, the sealing cover 120 is rotatably connected to the casing 110, the casing 110 includes a reagent storage chamber 111, a cold air circulation passage 112, a vacuum chamber 113 and a thermal insulation shell 114, which are sequentially disposed from inside to outside, the sealing cover 120 includes a liquid nitrogen storage chamber 121, a refrigeration chamber 122 and a liquid storage chamber 123, which are sequentially disposed in a transverse direction, a mounting chamber 1211 is disposed on a side opposite to the liquid nitrogen storage chamber 121, the liquid nitrogen storage chamber 121 is connected to a discharge pipe, one end of the discharge pipe is connected to an adjustment valve 1212, an output end of the adjustment valve 1212 is connected to a delivery pipe 1213, a pressure sensor 1214 is mounted on the delivery pipe 1213, one end of the delivery pipe 1213 extends to the interior of the refrigeration chamber 122, an end of the delivery pipe 1213, which is located at the refrigeration chamber 122, is sleeved with a heat absorption bag 1215, one end of the pressure increasing pipe 1217 communicates with the delivery pipe 1213.
In this embodiment, when the condenser 220 performs heat exchange, the temperature controller 116 controls the regulating valve 1212 to be electrically opened, the liquid nitrogen storage chamber 121 is fed into the heat absorption bag 1215 through the feeding pipe 1213, the heat absorption bag 1215 is bulged by the pressure, and strong cool air is formed in the heat absorption bag 1215, so that the high temperature air discharged from the condenser 220 is absorbed to form water vapor.
When liquid nitrogen is conveyed, the pressure of the conveying pipe 1213 is monitored in real time by using the pressure sensor 1214, and when the pressure of the conveying pipe 1213 is found to be insufficient, the conveying pipe 1213 is subjected to pressurization adjustment by using the pressure pump.
In addition, in the process of storing the reagent, the vacuum cavity 113 forms an isolation barrier for the shell 110, so that the flow of air is reduced, the reagent storage cavity 111 of the shell 110 is kept at a lower temperature continuously, and the reagent can be effectively stored at a low temperature.
Referring to fig. 4 to 5, the heat insulating shell 114 includes a first filling layer 1141, a second filling layer 1142, a heat insulating layer 1143, a first heat insulating layer 1144, a second heat insulating layer 1145 and a decorative layer 1146, which are sequentially arranged from inside to outside, the first heat insulating layer 1144 is made of a purlin board, the second heat insulating layer 1145 is made of a ceramic material, the decorative layer 1146 is made of a decorative foil, and the first filling layer 1141 and the second filling layer 1142 are respectively made of an EPDM board and an asbestos material; the EPDM sheet material and the asbestos material have stronger heat insulation property, so that the heat insulation performance of the shell 110 is enhanced; in addition, the pran board, the ceramic material and the decorative foil have strong heat insulation properties, so that the heat insulation performance of the housing 110 is enhanced, and the endothermic reaction between the cold air in the reagent storage chamber 111 and the external high-temperature air is avoided.
Further, a negative pressure motor is arranged on one side of the reagent storage cavity 111, which is located on the support seat 310, an output end of the negative pressure motor is connected with a negative pressure tube 1171, a discharge port 118 is formed on one side of the casing 110, which is close to the temperature controller 116, the negative pressure tube 1171 is inserted into the discharge port 118, and a sealing ring is arranged between the discharge port 118 and the negative pressure tube 1171; after the sampling of the reagent is completed, the negative pressure pump 117 is powered on to evacuate the air in the reagent storage cavity 111 through the negative pressure tube 1171 and the exhaust port 118, so that a negative pressure space is formed in the reagent storage cavity 111, and further, the air flowing with the outside is reduced, and the reagent storage cavity 111 is kept in a low-temperature state.
Referring to fig. 1 to 4, the refrigerating assembly 200 includes a compressor 210, a condenser 220, and a T-shaped barrel 230, wherein an output end and an input end of the compressor 210 are connected to a first communicating pipe 211 and a second communicating pipe 212, respectively, one end of the second communicating pipe 212 passes through a through hole of the refrigerating chamber 122 and extends into the reagent storage chamber 111, and is communicated with the cold air circulation passage 112, one end of the first communication pipe 211 is connected to the input end of the condenser 220, the output end of the condenser 220 is connected to the third communication pipe 221, one end of the third communication pipe 221 passes through the through hole of the refrigerating chamber 122 and extends into the reagent storage chamber 111, and is communicated with the cool air circulation passage 112, the T-shaped tube 230 is provided inside the cooling chamber 122, one end of the T-shaped cylinder 230 extends into the liquid storage chamber 123, and the other end is communicated with the third communicating pipe 221 through a humidifying pipe 233, and a water-absorbing cotton rod 231 and a ceramic atomizing plate 232 are transversely and sequentially arranged inside the T-shaped cylinder 230.
In this embodiment, the storage temperature is adjusted by the temperature controller 116, at this time, the temperature controller 116 controls the compressor 210 to compress air, and the compressed air is sent to the condenser 220 through the first communication pipe 211, after the temperature reduction process of the condenser 220, the cold air can be sent to the cold air circulation passage 112 through the second communication pipe 212, and the hot air inside the absorbent storage chamber 111 is subjected to heat exchange and then to temperature increase, and then is compressed again by the compressor 210 to complete air circulation.
Further, a water vapor discharge channel is formed in one side of the bottom of the casing 110, the water vapor discharge channel is communicated with the cold air circulation channel 112, and a sealing plug is inserted into the water vapor discharge channel; since moisture adheres to the wall surface of the cool air circulation passage 112 for a long time, moisture is easily deposited inside the cool air circulation passage 112, and therefore, after the use for a certain period of time, an operator needs to pull out the sealing plug, so that the moisture inside the cool air circulation passage 112 is discharged through the moisture discharge passage.
Referring to fig. 4, 6 and 8, the mixing assembly 300 includes two support bases 310, a rotation member 320, a support column 330, a small motor 340 and a turntable 350, the two support bases 310 and the small motor 340 are fixedly connected to one side of the bottom of the reagent storage chamber 111, and small motor 340 is located between two supporting seats 310, rotatable connection has rotation piece 320 between two supporting seats 310, rotation piece 320 is connected with support column 330, the first backup pad 331 of one end fixedly connected with of support column 330, the top of first backup pad 331 is provided with carousel 350, the top of carousel 350 is provided with second backup pad 332, carousel 350 and first backup pad 331 are fixed mutually through the bolt, the other end of support column 330 is connected with connecting rod 333, the output pot head of small motor 340 is equipped with fixed cover 341, the fixed surface of fixed cover 341 is connected with bent piece 342, the top of bent piece 342 and the one end fixed connection of connecting rod 333.
In this embodiment, after the sample collection is finished, place sample reagent bottle in container 360, it is rotatory to pass through small-size motor 340 circular telegram drive bent piece 342, makes connecting rod 333 drive support column 330 and uses rotation piece 320 as the axle center to drive the multi-angle and rock, can be with sample reagent mixing.
Referring to fig. 4, 6 to 8, the rotating member 320 includes a rectangular frame 321, auxiliary plates 322, a first rotating shaft 323 and a second rotating shaft 324, the auxiliary plates 322 are disposed on both the long side frame and the short side frame of the rectangular frame 321, the first rotating shaft 323 is fixedly connected between the auxiliary plates 322 on the long side frame of the rectangular frame 321, the first rotating shaft 323 is rotatably connected to the supporting column 330, the second rotating shaft 324 is fixedly connected to one side of the auxiliary plate 322 on the short side frame of the rectangular frame 321, and one end of the second rotating shaft 324 is rotatably connected to the supporting base 310.
In the embodiment, when the supporting column 330 drives the rotating disc 350 to swing, the supporting column 330 uses the second rotating shaft 324 as an axis to make the rectangular frame 321 perform an arc-shaped motion, or the supporting column 330 uses the first rotating shaft 323 as an axis to make the supporting column 330 perform an arc-shaped motion around the first rotating shaft 323.
In the embodiment of the present invention, a handle 115 is rotatably connected to the housing 110; the refrigerating box 100 with small volume is matched with the lifting handle 115 for use, so that the refrigerating box 100 is convenient to carry, and the sampling efficiency is improved.
In the embodiment of the present invention, a temperature controller 116 is installed at one side of the housing 110; the negative pressure pump 117, the regulating valve 1212, the pressure sensor 1214, the booster pump 1216, the compressor 210 and the condenser 220 are all in communication connection with the temperature controller 116, and the ceramic atomizing sheet 232 is electrically connected with the temperature controller 116; it is possible to facilitate the operator to check the temperature inside the reagent storage chamber 111 and to adjust the temperature inside the reagent storage chamber 111.
In the embodiment of the present invention, the sealing cover 120 and the case 110 are opened and closed by pressing the fastening member 124; it is convenient for the operator to open the sealing cover 120 and ensure a closed space for the reagent storage chamber 111 by the application of the pressing fastener 124.
In the embodiment of the present invention, the top of the sealing cover 120 is provided with a heat radiation window 125; the heat dissipation window 125 is used for facilitating the water vapor discharge after the liquid nitrogen absorbs heat.
In the embodiment of the present invention, a plurality of containers 360 are circumferentially distributed on the turntable 350, and a magnet 361 is disposed on each side of the bottom of each container 360; after sample reagent bottle placed in container 360, magnet 361 can attract sample reagent bottle, and sample reagent bottle keeps stable when the reagent mixing of being convenient for, avoids striking container 360.
Example two
Referring to fig. 10, an embodiment of the present invention further provides an operation method of a reagent refrigeration apparatus for an analyzer, including the following steps:
s1, mixing sample reagents: after the sample is collected, the sample reagent bottle is placed in the container 360, the small motor 340 is electrified to drive the crank block 342 to rotate, so that the connecting rod 333 drives the supporting column 330 to shake in multiple angles by taking the rotating piece 320 as an axis, and the sample reagent can be uniformly mixed;
s2, cold storage and preservation: on the way of the back detection, the storage temperature is adjusted by the temperature controller 116, at this time, the temperature controller 116 controls the compressor 210 to compress air and transmits the air to the condenser 220 through the first communication pipe 211, after the temperature reduction treatment of the condenser 220, the cold air can be transmitted to the cold air circulation passage 112 through the second communication pipe 212, the temperature is increased after the heat exchange is carried out by the hot air in the absorption reagent storage cavity 111, and the air is compressed again by the compressor 210 to complete the air circulation;
s3, cooling the cooling chamber 122: when the condenser 220 exchanges heat with the high-temperature air compressed by the compressor 210, the temperature controller 116 controls the regulating valve 1212 to be electrically opened, the liquid nitrogen storage chamber 121 is conveyed into the heat absorption bag 1215 through the conveying pipe 1213, the heat absorption bag 1215 is bulged by the pressure, and strong cold air is formed in the heat absorption bag 1215 to absorb the high-temperature air discharged from the condenser 220;
s4, cool air humidification: in the air circulation process, the water in the liquid storage cavity 123 is absorbed to one side of the ceramic atomizing sheet 232 through the water absorbing cotton rod 231, the ceramic atomizing sheet 232 is oscillated at high frequency by the temperature controller 116 through current, the water is thrown away from the small holes of the ceramic atomizing sheet 232 to form water mist, the water mist is conveyed to the third conveying pipe 1213 through the atomizing pipe to humidify the cold air, and the water droplets are attached to the wall surface of the cold air circulation channel 112 to continuously absorb the heat.
The method comprises the following specific implementation steps: after the sample is collected, the sample reagent bottle is placed in the container 360, the small motor 340 is electrified to drive the crank block 342 to rotate, so that the connecting rod 333 drives the supporting column 330 to shake in multiple angles by taking the rotating piece 320 as an axis, and the sample reagent can be uniformly mixed; on the way of the back detection, the storage temperature is adjusted by the temperature controller 116, at this time, the temperature controller 116 controls the compressor 210 to compress air and transmits the air to the condenser 220 through the first communication pipe 211, after the temperature reduction treatment of the condenser 220, the cold air can be transmitted to the cold air circulation passage 112 through the second communication pipe 212, the temperature is increased after the heat exchange is carried out by the hot air in the absorption reagent storage cavity 111, and the air is compressed again by the compressor 210 to complete the air circulation; when the condenser 220 exchanges heat with the high-temperature air compressed by the compressor 210, the temperature controller 116 controls the regulating valve 1212 to be electrically opened, the liquid nitrogen storage chamber 121 is conveyed into the heat absorption bag 1215 through the conveying pipe 1213, the heat absorption bag 1215 is bulged by the pressure, and strong cold air is formed in the heat absorption bag 1215 to absorb the high-temperature air discharged from the condenser 220; in the air circulation process, the water in the liquid storage cavity 123 is absorbed to one side of the ceramic atomizing sheet 232 through the water absorbing cotton rod 231, the ceramic atomizing sheet 232 is oscillated at high frequency by the temperature controller 116 through current, the water is thrown away from the small holes of the ceramic atomizing sheet 232 to form water mist, the water mist is conveyed to the third conveying pipe 1213 through the atomizing pipe to humidify the cold air, and the water droplets are attached to the wall surface of the cold air circulation channel 112 to continuously absorb the heat.
It should be noted that the model specifications of the temperature controller 116, the negative pressure pump 117, the regulating valve 1212, the pressure sensor 1214, the booster pump 1216, the compressor 210, the condenser 220, and the small motor 340 need to be determined by type selection according to the actual specification of the device, and the specific type selection calculation method adopts the prior art in the field, and therefore, detailed description is omitted.
The power supply and the principle of the temperature controller 116, the negative pressure pump 117, the regulating valve 1212, the pressure sensor 1214, the pressurizing pump 1216, the compressor 210, the condenser 220, and the small motor 340 will be apparent to those skilled in the art and will not be described in detail herein.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes may be made to the present invention by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. Reagent cold storage plant for analytical instrument, its characterized in that includes:
the refrigerator comprises a shell and a sealing cover, wherein the sealing cover is rotatably connected with the shell, the inside of the shell comprises a reagent storage cavity, an air conditioning circulation channel, a vacuum cavity and a heat preservation shell which are sequentially arranged from inside to outside, the inside of the sealing cover comprises a liquid nitrogen storage cavity, a refrigeration cavity and a liquid storage cavity which are sequentially and transversely arranged, an installation cavity is arranged on one side opposite to the liquid nitrogen storage cavity, the liquid nitrogen storage cavity is communicated with a discharge pipe, one end of the discharge pipe is connected with a regulating valve, the output end of the regulating valve is connected with a conveying pipe, a pressure sensor is installed on the conveying pipe, one end of the conveying pipe extends to the inside of the refrigeration cavity, one end of the conveying pipe, which is positioned in the refrigeration cavity, is sleeved with a heat absorption bag, a booster pump is arranged inside the installation cavity, and the, one end of the pressure increasing pipe is communicated with the conveying pipe;
the refrigeration component comprises a compressor, a condenser and a T-shaped cylinder, the output end and the input end of the compressor are respectively connected with a first communicating pipe and a second communicating pipe, one end of the second communicating pipe passes through the through hole of the refrigeration cavity and extends into the reagent storage cavity, and is communicated with the cold air circulation channel, one end of the first communicating pipe is connected with the input end of the condenser, the output end of the condenser is connected with a third communicating pipe, one end of the third communicating pipe passes through the through hole of the refrigerating cavity and extends into the reagent storage cavity, and with air conditioning circulation passageway intercommunication, a T shape section of thick bamboo sets up the inside in refrigeration chamber, just the one end of a T shape section of thick bamboo extends to inside, the other end in liquid storage chamber pass through the humidifying pipe with third communicating pipe intercommunication, the inside of a T shape section of thick bamboo transversely has set gradually cotton stick and the pottery atomizing piece of absorbing water.
2. The reagent refrigeration device for the analyzer as claimed in claim 1, wherein the heat insulating casing comprises a first filling layer, a second filling layer, a heat insulating layer, a first heat insulating layer, a second heat insulating layer and a decorative layer, which are arranged in sequence from inside to outside.
3. The reagent cooler of claim 2, wherein the first insulating layer is made of a pran sheet, the second insulating layer is made of a ceramic material, and the decorative layer is made of a decorative foil.
4. The reagent cooler of claim 1, wherein a handle is rotatably connected to the housing.
5. A reagent cooler for analyzer according to claim 1, wherein a temperature controller is mounted to one side of the housing.
6. A reagent cooler for analyzer according to claim 1, wherein the sealing cover and the case are opened and closed by a press fastener.
7. A reagent refrigerator for an analyzer according to claim 1, wherein a heat radiation window is provided on a top of the sealing cover.
8. The reagent refrigeration device for the analyzer according to claim 1, further comprising a blending component, wherein the blending component comprises two support bases, a rotating member, two support columns, a small motor and a rotating disc, the two support bases and the small motor are fixedly connected to one side of the bottom of the reagent storage cavity, the small motor is located between the two support bases, the rotating member is rotatably connected between the two support bases, the rotating member is connected with the support columns, one end of each support column is fixedly connected with a first support plate, the rotating disc is arranged above the first support plate, a second support plate is arranged above the rotating disc, the second support plate, the rotating disc and the first support plate are fixed through bolts, the other end of each support column is connected with a connecting rod, and a fixing sleeve is sleeved at the output end of the small motor, the surface of the fixed sleeve is fixedly connected with a bent block, and the top of the bent block is fixedly connected with one end of the connecting rod;
the rotating part comprises a rectangular frame, auxiliary plates, a first rotating shaft and a second rotating shaft, the auxiliary plates are arranged on the long side frame and the short side frame of the rectangular frame, the first rotating shaft is fixedly connected between the auxiliary plates on the long side frame of the rectangular frame, the first rotating shaft is rotatably connected with the supporting column, the second rotating shaft is fixedly connected to one side of the auxiliary plates on the short side frame of the rectangular frame, and one end of the second rotating shaft is rotatably connected with the supporting seat.
9. The reagent refrigeration device for the analyzer according to claim 8, wherein a plurality of containers are distributed around the turntable, and a magnet is disposed on one side of the bottoms of the plurality of containers.
10. An operation method of a reagent refrigeration apparatus for an analysis instrument, which is applied to the reagent refrigeration apparatus for an analysis instrument according to any one of claims 1 to 9, characterized by comprising the steps of:
s1, mixing sample reagents: after the sample is collected, placing a sample reagent bottle in a container, and electrifying a small motor to drive a crank block to rotate, so that a connecting rod drives a supporting column to drive a multi-angle swing by taking a rotating piece as an axis, and the sample reagent can be uniformly mixed;
s2, cold storage and preservation: on the way of the back-carrying detection, the storage temperature is adjusted through the temperature controller, at the moment, the temperature controller controls the compressor to compress air and conveys the air to the condenser through the first communicating pipe, after the temperature reduction treatment of the condenser, cold air can be conveyed to the cold air circulation channel through the second communicating pipe, the temperature is increased after heat exchange is carried out on hot air in the absorption reagent storage cavity, and the air is compressed again through the compressor to complete air circulation;
s3, cooling the refrigerating cavity: when the condenser exchanges heat with high-temperature air compressed by the compressor, the regulating valve is controlled to be powered on and opened by the temperature controller, the liquid nitrogen storage cavity is conveyed into the heat absorption bag through the conveying pipe, the heat absorption bag is raised under the action of pressure, strong cold air is formed in the heat absorption bag, and the high-temperature air discharged by the condenser can be absorbed;
s4, cool air humidification: in the air circulation process, the moisture in the inner part of the liquid storage cavity is absorbed to one side of the ceramic atomizing sheet through the water absorption cotton rod, the temperature controller enables the ceramic atomizing sheet to oscillate at high frequency through current, the moisture is thrown away from a small hole of the ceramic atomizing sheet to form water mist, the water mist is conveyed into the third conveying pipe through the atomizing pipe to humidify cold air, and water drops are attached to the wall surface of the cold air circulation channel to continuously absorb heat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110366998.7A CN113048687A (en) | 2021-04-06 | 2021-04-06 | Reagent refrigeration device for analyzer and working method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110366998.7A CN113048687A (en) | 2021-04-06 | 2021-04-06 | Reagent refrigeration device for analyzer and working method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113048687A true CN113048687A (en) | 2021-06-29 |
Family
ID=76517582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110366998.7A Pending CN113048687A (en) | 2021-04-06 | 2021-04-06 | Reagent refrigeration device for analyzer and working method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113048687A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102620509A (en) * | 2012-04-05 | 2012-08-01 | 河南新飞电器有限公司 | Fruit-vegetable box applicable to air-cooling refrigerator and rapid-cooling and moisturizing method of fruit-vegetable box |
| JP2016090088A (en) * | 2014-10-30 | 2016-05-23 | 日本通運株式会社 | Freshness retainer and container having the same |
| CN208026744U (en) * | 2018-02-11 | 2018-10-30 | 金博特（北京）生物科技有限公司 | A kind of chemical illumination immunity analysis instrument refrigeration reagent disc system |
| CN208145859U (en) * | 2018-02-08 | 2018-11-27 | 西安罗塞塔生物科技有限公司 | A kind of Novel rotary blending instrument |
| CN208419317U (en) * | 2018-05-15 | 2019-01-22 | 江苏涟水制药有限公司 | The storage device with refrigeration effect for chemical reagent |
| CN110683214A (en) * | 2019-09-03 | 2020-01-14 | 威尚生物技术（合肥）有限公司 | Reagent that can lower temperature keeps box |
-
2021
- 2021-04-06 CN CN202110366998.7A patent/CN113048687A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102620509A (en) * | 2012-04-05 | 2012-08-01 | 河南新飞电器有限公司 | Fruit-vegetable box applicable to air-cooling refrigerator and rapid-cooling and moisturizing method of fruit-vegetable box |
| JP2016090088A (en) * | 2014-10-30 | 2016-05-23 | 日本通運株式会社 | Freshness retainer and container having the same |
| CN208145859U (en) * | 2018-02-08 | 2018-11-27 | 西安罗塞塔生物科技有限公司 | A kind of Novel rotary blending instrument |
| CN208026744U (en) * | 2018-02-11 | 2018-10-30 | 金博特（北京）生物科技有限公司 | A kind of chemical illumination immunity analysis instrument refrigeration reagent disc system |
| CN208419317U (en) * | 2018-05-15 | 2019-01-22 | 江苏涟水制药有限公司 | The storage device with refrigeration effect for chemical reagent |
| CN110683214A (en) * | 2019-09-03 | 2020-01-14 | 威尚生物技术（合肥）有限公司 | Reagent that can lower temperature keeps box |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN208026744U (en) | A kind of chemical illumination immunity analysis instrument refrigeration reagent disc system | |
| CN210187311U (en) | Tissue grinding device with freezing function | |
| CN113501247A (en) | Rotary cage type ultralow-temperature biological sample automatic storing and taking system | |
| CN113048687A (en) | Reagent refrigeration device for analyzer and working method thereof | |
| CN207849867U (en) | A kind of preservation device and system | |
| CN112858540A (en) | Liquid workstation for solid phase extraction and chip array sample application | |
| CN111322807A (en) | Liquid nitrogen-free program cooling instrument | |
| CN218239542U (en) | Novel biochemical analyzer refrigeration device | |
| CN215263552U (en) | Antibody incubator suitable for western blotting | |
| CN207531755U (en) | Vacuum fumigation case | |
| CN214585027U (en) | Device for simulating soil freezing and thawing process under field condition | |
| CN210154165U (en) | Low-temperature cooling liquid circulating pump | |
| CN210593378U (en) | Outdoor portable low temperature constant temperature bath | |
| CN215029004U (en) | Medicine stability test box | |
| CN208733125U (en) | It is a kind of can the thermostatic machine case that remotely monitors of Internet of Things | |
| CN206911370U (en) | A kind of test samples low-temperature storage cabinet | |
| CN221131966U (en) | Blood sample anticoagulation device for blood sampling test | |
| CN217248407U (en) | Intelligent blending appearance with adjustable control by temperature change | |
| CN218987357U (en) | Cosmetic medical utility detection device | |
| CN220835539U (en) | Chemical industry reation kettle that can heat up fast and cool down | |
| CN108956257A (en) | Mixed incubating device | |
| CN212109125U (en) | Blood collection tube constant temperature control box for medical examination | |
| CN111043806B (en) | Gas refrigeration scheme absorption bottle sampling refrigeration and low-temperature storage composite device and method | |
| CN214892195U (en) | Liquid nitrogen freeze dryer | |
| CN211854569U (en) | Sampling refrigeration and low-temperature storage composite device for absorption bottle in gaseous refrigeration scheme |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210629 |