CN113018545B - Flow guiding adjusting device - Google Patents
Flow guiding adjusting device Download PDFInfo
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- CN113018545B CN113018545B CN202110229167.5A CN202110229167A CN113018545B CN 113018545 B CN113018545 B CN 113018545B CN 202110229167 A CN202110229167 A CN 202110229167A CN 113018545 B CN113018545 B CN 113018545B
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- 239000012530 fluid Substances 0.000 claims abstract description 43
- 210000005077 saccule Anatomy 0.000 claims abstract description 10
- 230000002612 cardiopulmonary effect Effects 0.000 claims description 13
- 230000010412 perfusion Effects 0.000 claims description 11
- 210000003437 trachea Anatomy 0.000 claims description 7
- 238000000338 in vitro Methods 0.000 claims description 6
- 230000008081 blood perfusion Effects 0.000 claims description 2
- 239000008280 blood Substances 0.000 description 51
- 210000004369 blood Anatomy 0.000 description 51
- 239000007789 gas Substances 0.000 description 41
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 23
- 230000017531 blood circulation Effects 0.000 description 23
- 229910052760 oxygen Inorganic materials 0.000 description 23
- 239000001301 oxygen Substances 0.000 description 23
- 210000004351 coronary vessel Anatomy 0.000 description 20
- 230000000747 cardiac effect Effects 0.000 description 12
- 210000000056 organ Anatomy 0.000 description 9
- 230000001105 regulatory effect Effects 0.000 description 9
- 238000002618 extracorporeal membrane oxygenation Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 230000036772 blood pressure Effects 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 210000000709 aorta Anatomy 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000006213 oxygenation reaction Methods 0.000 description 4
- 230000008602 contraction Effects 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 230000010349 pulsation Effects 0.000 description 3
- 210000003270 subclavian artery Anatomy 0.000 description 3
- 206010007556 Cardiac failure acute Diseases 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
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- 238000012986 modification Methods 0.000 description 2
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- 230000001360 synchronised effect Effects 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 206010021143 Hypoxia Diseases 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000010351 cardiac pulsation Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000000541 pulsatile effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1601—Control or regulation
- A61M1/1603—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
- A61M1/3659—Cannulae pertaining to extracorporeal circulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The invention relates to the technical field of fluid control, in particular to a flow guide adjusting device. The device comprises a catheter and an adjusting component, wherein the catheter comprises a catheter wall, a channel limited by the catheter wall and a side hole formed in the catheter wall, one end of the channel is an inlet, the other end of the channel is an outlet, and the side hole is communicated with the channel and is positioned between the inlet and the outlet; the adjusting component comprises an air source, a balloon and an air pipe, the balloon is arranged in the channel and positioned between the outlet and the side hole, and the air source is connected with the balloon through the air pipe and used for inflating or exhausting the balloon; the balloon expands after inflation to at least partially occlude the passageway and increase the amount of fluid discharged through the side aperture and contracts after deflation to reduce the occlusion of the passageway and increase the amount of fluid discharged through the outlet. The invention can adjust the flow direction and the flow rate of the fluid in the catheter by changing the state of the saccule.
Description
Technical Field
The disclosure relates to the technical field of fluid control, in particular to a flow guide adjusting device.
Background
Extracorporeal heart lung support (ECMO) is a percutaneous mechanical circulatory assist technique. An extracorporeal cardiopulmonary support aid is generally composed of three parts, a main frame, a pump head, and a membrane oxygenator. The main machine controls and monitors the operation of the extracorporeal cardiopulmonary support assist device, the pump head is used for circulating blood inside and outside the body, and the membrane oxygenator is used for providing oxygen and exchanging carbon dioxide in the blood discharged from the body. The extracorporeal cardiopulmonary support assisting device mainly drains venous blood in a patient body to the outside of the body, and the blood is oxygenated by the membrane oxygenator and carbon dioxide in the blood is removed and then returned to the patient body. Depending on the route of blood return, there are two main types of cardiopulmonary support aids, namely venous-venous (VV-ECMO) and venous-arterial (VA-ECMO), the former having only respiratory assistance and the latter having both circulatory and respiratory assistance.
The main problems of patients with acute heart failure are that the blood and oxygen supply of main organs including the heart is insufficient, and the insufficient oxygen supply of the heart further reduces the cardiac output to further aggravate symptoms, and finally the patients die due to exhaustion of heart energy. At present, VA-ECMO (femoral arteriovenous cannula) and IABP (Intra-Aortic Balloon Therapy) methods are generally adopted clinically for life support and improvement of heart failure. However, this method has several major drawbacks:
(1) the oxygenated blood with high oxygen content returned through the femoral artery is far away from the coronary artery inlet, which is not helpful to improve the blood oxygenation near the coronary artery inlet, so that the condition of insufficient oxygen supply of the heart cannot be improved. Also, due to the presence of the IABP balloon, it is not possible to infuse high oxygen content blood into the heart by cannulating the subclavian artery or other arterial circuits closer to the coronary portal.
(2) Due to the defect (1), when the oxygenation is insufficient due to the defect of the lung function of a patient, blood extruded into the coronary artery by the IABP balloon is blood with low oxygen content, so that the blood supply of the heart is increased, but the IABP balloon does not help to fundamentally relieve the problem of insufficient oxygen supply of the heart, and the development of the heart failure cannot be or cannot be corrected.
(3) The IABP balloon disturbs the aortic blood flow greatly, which is likely to cause poor perfusion of organs (liver, kidney) and the like, causing complications and being unfavorable for patient prognosis.
It can be seen that there is a lack of solutions in the related art to effectively solve or improve the problem of insufficient oxygen supply to the heart itself.
Disclosure of Invention
In view of the defects of the prior art, the present disclosure provides a flow guiding adjustment device capable of adjusting the flow direction and flow rate of fluid in a catheter by changing the state of a balloon. When the blood flow direction and/or flow in the catheter can be changed according to clinical requirements when the blood flow direction and/or flow in the catheter are/is assisted by using the coronary artery perfusion assisting device disclosed by the invention, the blood volume of coronary artery perfusion and the blood oxygen content in blood are increased, and the problem of insufficient oxygen supply of the heart is improved or solved.
The present disclosure provides a diversion regulating device comprising a catheter for diverting blood in an extracorporeal cardiopulmonary support aid and a regulating assembly for regulating the flow direction and/or flow rate of blood in the catheter; wherein,
the catheter comprises a catheter wall, a channel limited by the catheter wall and a side hole formed in the catheter wall, wherein one end of the channel is an inlet, the other end of the channel is an outlet, and the side hole is communicated with the channel and is positioned between the inlet and the outlet;
the adjusting assembly comprises a gas source, a balloon and a gas pipe, the balloon is arranged in the channel and positioned between the outlet and the side hole, and the gas source is connected with the balloon through the gas pipe and used for inflating or exhausting the balloon; the balloon is inflated after inflation to at least partially occlude the passageway and increase the amount of fluid discharged through the side aperture, and deflated after deflation to reduce occlusion of the passageway and increase the amount of fluid discharged through the outlet.
The side hole is arranged on the tube wall of the catheter, the inflatable saccule is arranged in the catheter, and the saccule is inflated or exhausted by using an external air source to flexibly adjust the flow direction and the flow rate of fluid in the catheter. Specifically, when the balloon is inflated by an external air source, the balloon is gradually inflated to at least partially block the channel, at the moment, the fluid cannot be smoothly discharged from the outlet of the channel, and the pressure applied to the tube wall by the fluid accumulated between the inlet of the channel and the balloon is increased to force the fluid to be discharged to the side hole; when the balloon deflates, the resistance of the balloon to the fluid decreases and the fluid is more easily expelled from the channel outlet, thereby reducing the amount of fluid expelled from the side hole.
When the diversion adjusting device disclosed by the disclosure is used for blood perfusion, the blood flow direction can be changed according to clinical requirements so as to perfuse organs in different directions. Specifically, when the adjusting device disclosed by the disclosure is used for assisting in vitro cardiopulmonary support, the side hole of the catheter can be placed near the entrance of a coronary artery of the heart, and when blood is ejected from the heart, the balloon is inflated to enable oxygenated blood to be ejected to the direction of the entrance of the coronary artery from the side hole, so that the blood pressure, the blood flow and the oxygen content of the blood at the entrance of the coronary artery are increased; the saccule is contracted at the time except the cardiac ejection cycle, so that most of blood flows out along the outlet direction of the channel, and the perfusion to other organs except the heart is increased, thereby improving or solving the problem of insufficient oxygen supply of the heart.
Drawings
In order to more clearly illustrate the technical solution of the present disclosure, the drawings used in the description of the embodiment or the prior art will be briefly described below. It is apparent that the drawings in the following description are only some embodiments of the disclosure, and that other drawings may be derived from those drawings by a person of ordinary skill in the art without inventive effort.
Fig. 1 is a schematic structural diagram of a diversion adjusting device in a balloon contraction state according to an embodiment of the present disclosure;
FIG. 2 is a schematic structural diagram of a diversion adjusting device provided by an embodiment of the present disclosure in a balloon inflation state;
FIG. 3 is a schematic view of blood flow direction with a balloon deflated as provided by embodiments of the present disclosure;
FIG. 4 is a schematic view of blood flow direction in a balloon inflated state provided by embodiments of the present disclosure;
fig. 5 is a schematic structural diagram of a diversion adjusting device in a balloon contraction state according to an embodiment of the present disclosure;
FIG. 6 is a schematic structural diagram of a diversion adjustment apparatus provided by an embodiment of the present disclosure in a balloon-inflated state;
FIG. 7 is a schematic view of blood flow direction with a balloon deflated as provided by embodiments of the present disclosure;
fig. 8 is a schematic view of blood flow direction in a balloon inflated state provided by embodiments of the present disclosure.
In the figure: 1-a catheter, 2-a regulating component; 11-tube wall, 12-channel, 13-side hole, 14-outlet, 15-inlet; 21-balloon, 22-trachea, 23-first gas source, 24-first valve, 25-second gas source, 26-second valve, 27-valve plate; 3-subclavian artery, 4-coronary artery.
Detailed Description
In order to make the technical solutions of the present disclosure better understood by those skilled in the art, the technical solutions of the embodiments of the present disclosure will be clearly and completely described below with reference to the drawings in the embodiments of the present disclosure, and it is obvious that the described embodiments are only some embodiments of the present disclosure, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments disclosed herein without making any creative effort, shall fall within the protection scope of the present disclosure.
It should be noted that the terms "first," "second," and the like in the description and claims of the present disclosure and in the drawings are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used is interchangeable under appropriate circumstances such that the embodiments of the disclosure described herein are capable of operation in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprising" and "having," as well as any variations thereof, are intended to cover non-exclusive inclusions.
The main problem of patients with acute heart failure is insufficient blood and oxygen supply for organs including the heart, and the VA-ECMO combined IABP method adopted clinically at present can solve the problem of blood supply for the heart but cannot improve the problem of oxygen supply for the heart.
The key to improving the problem of cardiac oxygenation is to introduce blood with high oxygen content into the coronary arteries, and the blood oxygenated extracorporeally is higher than the arterial blood, which inevitably improves cardiac oxygenation if the extracorporeally oxygenated blood is directed into the coronary arteries. However, when the blood cannula is used for back-feeding blood, the flow rate of the blood flow is determined by the power source such as an extracorporeal blood pump and the pressure flow resistance, the blood flow direction is determined by the tube placing position, the cannula opening and the like, and the blood flow direction in the blood conveying process cannot be changed. That is, existing cannulae do not meet the need for delivering high oxygen content blood in close proximity to the coronary arteries. Therefore, the embodiment of the present disclosure provides a diversion adjusting device, which can change the flow direction of oxygenated blood in a human body, increase blood oxygen supply to coronary arteries during cardiac ejection, increase the effect of blood oxygen supply to other organs besides cardiac ejection, simulate blood pressure and blood flow pulsation generated by cardiac pulsation, and improve or eliminate the problem of cardiac hypoxia.
Fig. 1 shows a flow guiding adjustment device provided by an embodiment of the present disclosure, please refer to fig. 1, the device includes a conduit 1 and an adjustment assembly 2, the conduit 1 is a hose for guiding fluid, and the adjustment assembly 2 is used for adjusting the flow direction and/or the flow rate of the fluid in the conduit 1. In particular, when the device of the present disclosure is applied to an extracorporeal cardiopulmonary support assist device, the device may belong to a part of the extracorporeal cardiopulmonary support assist device, in this case, the catheter is used for guiding oxygenated blood, and the adjusting component is used for adjusting the flow direction and/or flow rate of the oxygenated blood in the human body.
Referring to fig. 1, the catheter 1 may include a tubular wall 11, a channel 12 defined by the tubular wall 11, and a side hole 13 opened in the tubular wall 11, wherein one end of the channel 12 is an inlet 15, and the other end is an outlet 14, and the side hole 13 is communicated with the channel 12 and is located between the inlet 15 and the outlet 14. In a possible implementation, the side holes 13 may be strip-shaped holes arranged along the length of the catheter 1 to minimize the influence of the side holes 13 on the cross-section of the channel 12, ensuring that fluid leaks as little as possible to the side holes 13 during the flow from the inlet 15 to the outlet 14.
The adjustment assembly 2 may comprise a gas source, a balloon 21 and a trachea 22, the balloon 21 being disposed within the channel 12 between the outlet 14 and the side hole 13; the air source is connected with the saccule 21 through an air pipe 22 and is used for inflating or exhausting the saccule 21; the balloon 21 expands after inflation to at least partially occlude the passageway 12 increasing the amount of fluid expelled through the side aperture 13 and the balloon 21 contracts after deflation to reduce the obstruction of the passageway 12 increasing the amount of fluid expelled through the outlet 14.
In one possible implementation, the gas source includes a first gas source 23 and a second gas source 25, the first gas source 23 is used for inflating the balloon 21, the second gas source 25 is used for exhausting the balloon 21, specifically, the first gas source 23 may be a high-pressure gas source, the second gas source 25 may be a negative-pressure gas source or an atmosphere, and both the first gas source 23 and the second gas source 25 are disposed outside the channel 12. One end of the air pipe 22 is connected with the balloon 21, the other end is a branch pipe, the branch pipe comprises a first branch pipe and a second branch pipe, the first branch pipe is connected with the first air source 23, and the second branch pipe is connected with the second air source 25. The first branch pipe is provided with a first valve 24, the second branch pipe is provided with a second valve 26, the first valve 24 is used for communicating/closing gas transmission between the first gas source 23 and the balloon 21, and the second valve 26 is used for communicating/closing gas transmission between the second gas source 25 and the balloon 21. When the balloon is inflated, the valve communicated with the high-pressure air source through the balloon is opened, and the balloon is inflated through the external high-pressure air source. When the air is deflated, the valve for connecting the balloon with the atmosphere can be opened, the air in the balloon can be rapidly discharged into the atmosphere due to the self contraction force of the balloon, and the air outlet of the second branch pipe can be connected with a negative pressure source to accelerate the air discharge.
In the disclosed embodiment, the flow direction of the fluid is associated with the state of the balloon, and the flow direction of the fluid in the catheter can be adjusted by changing the state of the balloon. The method comprises the following specific steps:
the first valve 24 is closed to block the communication between the first gas source 23 and the balloon 21, and the second valve 26 is opened to communicate the second gas source 25 with the balloon 21, or the first valve 24 is closed after the balloon 21 is deflated to keep the balloon 21 in a deflated state, as shown in fig. 1, at this time, the balloon 21 hardly blocks the channel 12, and the resistance in the channel 12 is much smaller than that of the vessel wall 11, so that most of the fluid entering the channel 12 flows out through the outlet 14, and little or no fluid flows out through the side hole 13. Closing the second valve 26, blocking the communication between the second gas source 25 and the balloon 21, opening the first valve 24, connecting the first gas source 23 and the balloon 21, and driving the first gas source 23 to inflate the balloon 21, and inflating the balloon 21 to block the passage 12 between the inlet 15 and the outlet 14, so as to force the fluid which can flow out from the outlet 14 to be discharged from the side hole 13. In practice, the degree of obstruction of the channel 12 by the balloon 21 can be adjusted by controlling the inflation amount, and when the balloon 21 does not completely obstruct the channel 12, the fluid can flow out from the side hole 13 and the outlet 14 at the same time, and when the balloon 21 completely obstructs the channel 12, the fluid can flow out from the side hole 13 only.
The adjusting device provided by the embodiment of the disclosure can be used for assisting in vitro cardiopulmonary support to dynamically adjust the perfusion direction and perfusion volume of blood flow, thereby improving or solving the problem of insufficient oxygen supply of the heart. Fig. 3 and 4 are views showing an application scenario of the adjusting device provided by the present disclosure, please refer to fig. 3, one end of the catheter 1 is connected with ECMO in vitro, the other end of the catheter 1 is inserted from the subclavian artery 3, and enters other aorta after passing through the cardiac aorta, the side hole 13 of the catheter 1 is placed near the entrance of the cardiac coronary artery 4, the blood oxygenated in vitro is introduced into the channel 12 through the entrance 15, the monitoring device is used to monitor and obtain the blood ejection cycle of the heart, during the heart blood ejection, the balloon 21 is inflated to eject the oxygenated blood from the side hole 13 to the entrance direction of the coronary artery 4 (as shown in fig. 4), so as to increase the blood pressure, blood flow and blood oxygen content at the entrance of the coronary artery 4; the balloon 21 is deflated at a time other than the cardiac ejection cycle to allow most of the blood flow to flow out in the direction of the channel outlet 14 (as shown in fig. 3), thereby increasing perfusion to organs other than the heart.
Fig. 3 and 4 are both cannulated through the subclavian artery 3, but the devices provided by embodiments of the present disclosure may be used in other locations where cannulation is desired and where a change in blood flow direction is desired.
Fig. 5 shows another diversion regulating device provided by the embodiment of the present disclosure, please refer to fig. 5, the device includes a conduit 1 and a regulating assembly 2, the conduit 1 is a hose for diverting fluid, and the regulating assembly 2 is used for regulating the flow direction and/or flow rate of fluid in the conduit 1. In particular, when the device of the present disclosure is applied to an extracorporeal cardiopulmonary support assist device, it may belong to a part of the extracorporeal cardiopulmonary support assist device, in this case, the catheter 1 is used for guiding oxygenated blood, and the adjusting component 2 is used for adjusting the flow direction and/or flow rate of the oxygenated blood in the human body.
The catheter 1 can comprise a catheter wall 11, a channel 12 defined by the catheter wall 11, a side hole 13 formed in the catheter wall 11, and a valve plate 27 arranged near the side hole 13, wherein one end of the channel 12 is an inlet 15, the other end of the channel 12 is an outlet 14, the side hole 13 is communicated with the channel 12 and is positioned between the inlet 15 and the outlet 14, one side of the valve plate 27 is connected with the edge of the side hole 13, and the other side of the valve plate 27 is a movable side.
The regulating component 2 comprises a gas source, a balloon 21 and a trachea 22, wherein the balloon 21 is arranged in the channel 12 and is positioned between the outlet 14 and the side hole 13; a gas source is connected to the balloon 21 via a gas tube 22 for inflating or deflating the balloon 21. The gas source includes a first gas source 23 for inflating the balloon 21 and a second gas source 25 for exhausting the balloon 21, specifically, the first gas source 23 may be a high-pressure gas source, and the second gas source 25 may be a negative-pressure gas source or an atmosphere. One end of the air pipe 22 is connected with the balloon 21, the other end of the air pipe is a branch pipeline, the branch pipeline comprises a first branch pipe and a second branch pipe, the first branch pipe is connected with a first air source 23, the second branch pipe is connected with a second air source 25, and the first air source 23 and the second air source 25 are both arranged outside the channel 12. A first valve 24 is provided in the first branch and a second valve 26 is provided in the second branch, the first valve 24 being adapted to communicate/close the gas transfer between the first gas source 23 and the balloon 21 and the second valve 26 being adapted to communicate/close the gas transfer between the second gas source 25 and the balloon 21. It should be noted that the trachea may be disposed along the inner wall or the outer wall of the catheter, or of course, a trachea channel may be disposed on the wall of the catheter, and the catheter is inserted into the channel of the catheter from the trachea channel, so that the inner wall of the catheter is smooth, and the obstruction of the trachea to the fluid in the channel is reduced as much as possible.
In a possible realization, the valve plate 27 is connected to the edge of the lateral hole 13 by means of elastic elements. When the saccule 21 is inflated and expanded, the expanded saccule 21 blocks the channel 12 to prevent the fluid from being discharged from the outlet 14, the pressure exerted by the fluid accumulated in the channel 12 on the tube wall 11 is increased, when the pressure is greater than the supporting force of the elastic element, the movable side of the valve plate deflects away from the side hole 13, and the fluid in the channel 12 is discharged from the side hole 13. When the saccule 21 is deflated, the obstruction in the channel 12 is gradually eliminated, the fluid can be smoothly discharged from the outlet 14, so that the pressure of the fluid on the tube wall 11 is reduced, the pressure applied on the valve plate is also reduced, and when the pressure applied on the valve plate is smaller than the supporting force of the elastic element, the elastic element drives the movable side of the valve plate to block the side hole 13, and the initial position is recovered, thereby achieving the effect of automatic reset.
In one possible implementation, the movable side of the valve plate is attached to a pull cable that extends toward the entrance 15 of the passageway 12. When the traction cable is in a relaxed state, the movable side of the valve plate deflects in a direction away from the side hole 13, so that the side hole 13 is opened, and fluid is allowed to flow out of the side hole 13, and when the traction cable is in a tightened state, the movable side of the valve plate is close to the side hole 13, so that the side hole 13 is sealed, and the fluid is prevented from flowing out of the side hole 13. Specifically, when the balloon 21 is inflated and expanded, the valve plate is controlled to be opened through the traction cable, so that the fluid in the channel 12 can be discharged through the side hole 13, and when the balloon 21 is deflated, the valve plate is controlled to be closed through the traction cable, so that the fluid in the channel 12 is discharged from the outlet 14.
Furthermore, the shape and the size of the valve plate are matched with the side hole 13, when the valve plate blocks the side hole 13, the outer wall of the valve plate is flush with the outer wall of the catheter 1, and therefore the blood vessel tissue is prevented from being hooked when the catheter is pulled out.
Fig. 7 and 8 are schematic views of the state in which the adjusting device of the embodiment of the present disclosure is used for extracorporeal cardiopulmonary support assistance. Referring to fig. 7, the inlet 15 of the catheter 1 is connected to the ECMO, the side hole 13 of the catheter 1 is placed near the inlet of the coronary artery 4 of the heart, the blood oxygenated in vitro is injected into the catheter channel 12 through the inlet 15, the balloon 21 is contracted at a time other than the cardiac ejection cycle, and the valve plate is closed, so that most of the blood flows out along the channel outlet 14, and the perfusion is performed on organs other than the heart. Referring to fig. 8, during the cardiac ejection, the balloon 21 is inflated and the valve plate is opened, so that the oxygenated blood is ejected from the side hole 13 to the entrance of the coronary artery 4, thereby increasing the blood pressure, blood flow and blood oxygen content at the entrance of the coronary artery.
The disclosed embodiments may increase the perfusion volume to the coronary arteries and the blood oxygen content in the perfused blood by outputting blood flow in a pulsatile manner synchronized with the heart when the catheter side hole is placed near the entrance of the coronary artery of the heart. Blood ejection is synchronized with the heart, so that blood pressure and blood flow pulsation generated by the heart pulsation can be simulated, and the blood flow perfusion effect of downstream organs (such as a liver and a kidney) is improved. And, set up the valve plate at the side opening border, cooperate the sacculus state to carry out the open and shut control to the valve plate, the valve plate can guide blood to export outflow under closed condition, under open condition, can guide blood to slowly flow to the aorta, prevents to directly erode the aorta wall from leading to the intermediate layer from the blood that the side opening spurted.
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above examples only show several embodiments of the present disclosure, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for those skilled in the art, various changes and modifications can be made without departing from the concept of the present disclosure, and these changes and modifications are all within the scope of the present disclosure. Therefore, the protection scope of the present disclosure should be subject to the appended claims.
Claims (10)
1. A kind of flow guide adjusting device, characterized by: the flow guide adjusting device is used for assisting in vitro cardiopulmonary support to dynamically adjust the blood perfusion direction and perfusion amount, and comprises a catheter and an adjusting component, wherein the catheter is used for guiding fluid, and the adjusting component is used for adjusting the flow direction and/or flow of the fluid in the catheter; the catheter comprises a catheter wall, a channel defined by the catheter wall and a side hole formed in the catheter wall, wherein one end of the channel is an inlet, the other end of the channel is an outlet, and the side hole is communicated with the channel and is positioned between the inlet and the outlet; the adjusting assembly comprises a gas source, a balloon and a gas pipe, the balloon is arranged in the channel and positioned between the outlet and the side hole, and the gas source is connected with the balloon through the gas pipe and used for inflating or exhausting the balloon; the balloon is inflated after inflation to at least partially occlude the passageway and increase the amount of fluid discharged through the side aperture, and deflated after deflation to reduce occlusion of the passageway and increase the amount of fluid discharged through the outlet.
2. The apparatus of claim 1, wherein the gas source is disposed outside of the channel.
3. The apparatus of claim 2, wherein the gas source comprises a first gas source for inflating the balloon and a second gas source for deflating the balloon.
4. The apparatus of claim 3, wherein the first gas source is a high pressure gas source; the second air source is a negative pressure air source or atmosphere.
5. The device of claim 3, wherein the trachea has one end connected to the balloon and another end comprising a branch line, the branch line comprising a first branch line and a second branch line, the first branch line connected to the first gas source and the second branch line connected to the second gas source.
6. The apparatus of claim 5, wherein the first branch is provided with a first valve and the second branch is provided with a second valve.
7. The device of claim 1, further comprising a valve plate, one side of the valve plate being attached to the periphery of the side opening and the other side of the valve plate being a movable side, wherein the movable side of the valve plate is proximate to the side opening when the balloon is in the deflated state and the movable side of the valve plate is deflected away from the side opening when the balloon is in the inflated state.
8. The apparatus of claim 7, wherein the valve plate is shaped and sized to match the side opening.
9. The device of claim 7, wherein the valve plate is connected to the edge of the side opening by an elastic member; the movable side of the valve plate can deflect away from the side hole under the condition that the balloon is inflated; under the condition that the saccule contracts, the elastic part can drive the movable side of the valve plate to be close to the side hole.
10. The apparatus of claim 7, wherein the movable side of the valve plate is attached to a pull cable that extends toward the entrance of the passageway, wherein the movable side of the valve plate is deflected away from the side opening when the pull cable is in a relaxed state, and wherein the movable side of the valve plate is proximate the side opening when the pull cable is in a tightened state.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110229167.5A CN113018545B (en) | 2021-03-02 | 2021-03-02 | Flow guiding adjusting device |
| PCT/CN2021/092297 WO2022183591A1 (en) | 2021-03-02 | 2021-05-08 | Flow guide adjustment device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110229167.5A CN113018545B (en) | 2021-03-02 | 2021-03-02 | Flow guiding adjusting device |
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| CN113018545A CN113018545A (en) | 2021-06-25 |
| CN113018545B true CN113018545B (en) | 2021-11-19 |
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| CN202110229167.5A Active CN113018545B (en) | 2021-03-02 | 2021-03-02 | Flow guiding adjusting device |
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| CN (1) | CN113018545B (en) |
| WO (1) | WO2022183591A1 (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204261112U (en) * | 2014-11-21 | 2015-04-15 | 宋会中 | A kind of hemodialysis blood flow actuator |
| CN104791525A (en) * | 2015-04-24 | 2015-07-22 | 杨举 | Valve type single-way gate valve |
| CN208243891U (en) * | 2017-07-31 | 2018-12-18 | 河南亚太医疗用品有限公司 | A kind of disposable tracheostomy tube |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6436071B1 (en) * | 1999-06-08 | 2002-08-20 | The Trustees Of Columbia University In The City Of New York | Intravascular systems for corporeal cooling |
| US20050059923A1 (en) * | 2003-09-17 | 2005-03-17 | Ricardo Gamboa | Fenestration with intrinsic means of selective closure incorporated to a tubular body and used in interventional cardiovascular procedures |
| US9629987B2 (en) * | 2013-01-22 | 2017-04-25 | Alcoyne Lifesciences, Inc. | Systems and methods for shunting fluid |
| US9138567B2 (en) * | 2013-03-11 | 2015-09-22 | Covidien Lp | Controlling catheter flow |
| US10328196B2 (en) * | 2016-10-13 | 2019-06-25 | The Cleveland Clinic Foundation | Systems and methods for peripheral vascular cannulation |
| CN108159548B (en) * | 2017-12-26 | 2024-04-02 | 中国人民解放军总医院 | Recoverable transjugular vein portal body shunt thrombolysis catheter |
| CN108525109A (en) * | 2018-05-04 | 2018-09-14 | 林若骐 | A kind of conduit device being implanted into through cutaneous artery |
| CN113018543B (en) * | 2021-03-02 | 2021-10-08 | 江苏赛腾医疗科技有限公司 | Diversion control system |
-
2021
- 2021-03-02 CN CN202110229167.5A patent/CN113018545B/en active Active
- 2021-05-08 WO PCT/CN2021/092297 patent/WO2022183591A1/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204261112U (en) * | 2014-11-21 | 2015-04-15 | 宋会中 | A kind of hemodialysis blood flow actuator |
| CN104791525A (en) * | 2015-04-24 | 2015-07-22 | 杨举 | Valve type single-way gate valve |
| CN208243891U (en) * | 2017-07-31 | 2018-12-18 | 河南亚太医疗用品有限公司 | A kind of disposable tracheostomy tube |
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| CN113018545A (en) | 2021-06-25 |
| WO2022183591A1 (en) | 2022-09-09 |
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