CN113017602B - Respiratory frequency measuring method and physical sign monitor - Google Patents

Respiratory frequency measuring method and physical sign monitor Download PDF

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CN113017602B
CN113017602B CN202110216015.1A CN202110216015A CN113017602B CN 113017602 B CN113017602 B CN 113017602B CN 202110216015 A CN202110216015 A CN 202110216015A CN 113017602 B CN113017602 B CN 113017602B
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respiratory
waveform
coordinate value
amplitude
sign monitor
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CN113017602A (en
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吴文奇
王法凌
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FUZHOU KANGDA BAFANG ELECTRONIC TECHNOLOGY CO LTD
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FUZHOU KANGDA BAFANG ELECTRONIC TECHNOLOGY CO LTD
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816Measuring devices for examining respiratory frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The invention discloses a respiratory frequency measuring method and a physical sign monitor. The respiratory frequency measuring method comprises the following steps: acquiring a photoplethysmogram acquired by a blood oxygen saturation sensor; identifying the amplitude and the coordinate value of each pulse of the photoplethysmography, and performing interpolation processing on the amplitude and the coordinate value to obtain a respiration waveform, wherein the respiration waveform is a waveform representing the relationship between the amplitude and the coordinate value; a respiratory frequency is calculated based on the respiratory waveform. The physical sign monitor executes the respiratory frequency measuring method. According to the invention, no part is required to be additionally arranged on the existing sign monitor, so that the sign monitor can ensure the convenience of the sign monitor while increasing the respiratory frequency measurement function, and the respiratory monitoring can be realized without increasing the cost.

Description

Respiratory frequency measuring method and physical sign monitor
Technical Field
The invention relates to the field of physical sign monitoring, in particular to a respiratory frequency measuring method and a physical sign monitor.
Background
Medical personnel hope at the in-process that vital sign gathered that it is better that carrying equipment is less, and at present, portable guardianship equipment can only detect body temperature, blood pressure, oxyhemoglobin saturation, pulse rate parameter, breathes and can only pass through medical personnel's manual computation and type-in, and the operation is convenient, inefficiency inadequately. And the breathing rate can be detected by using other additional equipment, so that the workload of medical personnel is increased, the operation is inconvenient, and the efficiency is influenced.
Disclosure of Invention
The invention aims to provide a respiratory frequency measuring method capable of being integrated on the existing physical sign monitor and the physical sign monitor integrated with the respiratory frequency measuring function.
In order to achieve the purpose, the invention provides the following scheme:
a respiratory rate measurement method, the respiratory rate measurement method comprising:
step 1: acquiring a photoplethysmogram acquired by a blood oxygen saturation sensor;
and 2, step: identifying the amplitude and the coordinate value of each beat of pulse of the photoplethysmography, and carrying out interpolation processing on the amplitude and the coordinate value to obtain a respiratory waveform, wherein the respiratory waveform is a waveform representing the relationship between the amplitude and the coordinate value;
and step 3: a respiratory frequency is calculated based on the respiratory waveform.
Optionally, between step 1 and step 2, further comprising:
filtering the photoplethysmographic pulse wave.
Optionally, the filtering the photoplethysmography specifically includes:
and filtering the photoplethysmography by adopting a band-pass filter with the cut-off frequency of 0.1-4.2 Hz.
Optionally, between step 2 and step 3, further comprising:
and performing autocorrelation processing on the respiratory waveform.
Optionally, step 3 specifically includes:
according to F =100 × n/(x) n+i -x i ) Calculating a respiratory frequency F, wherein F = F n/(x) n+i -x i ) Calculating a respiratory frequency F, wherein F is a sampling frequency x n+i Is the coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
The invention also provides a sign monitor, comprising: a blood oxygen saturation sensor and a processor, the processor comprising a respiratory rate calculation module, the respiratory rate calculation module comprising:
the photoelectric volume pulse wave acquisition unit is used for acquiring the photoelectric volume pulse wave acquired by the blood oxygen saturation sensor;
the respiratory waveform determining unit is used for identifying the amplitude and the coordinate value of each pulse of the photoplethysmogram pulse wave, and performing interpolation processing on the amplitude and the coordinate value to obtain a respiratory waveform, wherein the respiratory waveform is a waveform representing the relationship between the amplitude and the coordinate value;
a respiratory frequency calculation unit for calculating a respiratory frequency based on the respiratory waveform.
Optionally, the respiratory rate calculation module further includes:
and the photoelectric volume pulse wave filtering unit is used for filtering the photoelectric volume pulse wave.
Optionally, the photoplethysmography filtering unit specifically includes:
and the photoelectric volume pulse wave filtering subunit is used for filtering the photoelectric volume pulse wave by adopting a band-pass filter with the cut-off frequency of 0.1-4.2 Hz.
Optionally, the respiratory rate calculating module further includes:
and the autocorrelation processing unit is used for carrying out autocorrelation processing on the respiratory waveform.
Optionally, the respiratory frequency calculation unit specifically includes:
a respiratory rate calculation subunit for calculating a respiratory rate according to F = F n/(x) n+i -x i ) Calculating the respiratory frequency F, wherein F is the sampling frequency x n+i Is a coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
According to the specific embodiment provided by the invention, the invention discloses the following technical effects: the respiratory frequency measuring method and the physical sign monitor provided by the invention obtain respiratory waves based on the photoplethysmography acquired by the blood oxygen saturation sensor, namely, a relationship curve between the amplitude and the coordinate value is constructed by identifying the amplitude and the coordinate value of each beat of pulse in the photoplethysmography acquired by the blood oxygen saturation sensor, so that the respiratory waveform is obtained. And further realizes the respiratory frequency measurement based on the respiratory waveform. Compared with the method for measuring the respiratory rate by using the thoracic impedance and respiratory airflow methods in the prior art, the method for measuring the respiratory rate of the physical sign monitor does not need to add a part on the conventional physical sign monitor, not only increases the respiratory rate measuring function of the physical sign monitor, but also ensures the convenience of the physical sign monitor and saves the cost.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without inventive exercise.
Fig. 1 is a schematic flowchart of a respiratory rate measuring method according to embodiment 1 of the present invention;
FIG. 2 is a diagram of photoplethysmography in accordance with embodiment 1 of the present invention;
FIG. 3 is a diagram showing a respiratory waveform in example 1 of the present invention;
FIG. 4 is a waveform diagram of a respiration waveform obtained by auto-correlation according to example 1 of the present invention;
figure 5 is a schematic structural diagram of a respiratory rate measurement module in the sign monitor provided in embodiment 2 of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The invention aims to provide a respiratory frequency measuring method capable of being integrated on the existing physical sign monitor and the physical sign monitor integrated with the respiratory frequency measuring function.
In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, the present invention is described in detail with reference to the accompanying drawings and the detailed description thereof.
Example 1
The embodiment provides a respiratory rate measuring method which can be integrated on the existing physical sign monitor, and the respiratory rate measuring function is integrated on the physical sign monitor without adding any accessory. The respiratory rate measuring method comprises the following steps:
step 1: acquiring a photoplethysmogram acquired by the blood oxygen saturation sensor, wherein the photoplethysmogram is shown in figure 2.
Step 2: and identifying the amplitude and the coordinate value of each pulse of the photoplethysmography pulse wave, and performing interpolation processing on the amplitude and the coordinate value to obtain a respiration waveform, wherein the respiration waveform is a waveform representing the relationship between the amplitude and the coordinate value.
Specifically, the amplitude and position of each pulse of the photoplethysmography pulse wave are identified and marked as (x) 0 ,y 0 ),(x 1 ,y 1 )…(x n ,y n ) X is coordinate value and y is amplitude. The height of the vertical line in fig. 2 represents the amplitude and the horizontal displacement represents the coordinate position. Selecting a natural boundary condition pair (x) using cubic spline interpolation 0 ,y 0 ),(x 1 ,y 1 )…(x n ,y n ) Interpolation is performed to form a respiration waveform, as shown in fig. 3.
And step 3: a respiratory frequency is calculated based on the respiratory waveform. In particular, F = F × n/(x) n+i -x i ) Calculating a respiratory frequency F, wherein F is a sampling frequency, which in this embodiment is 100,x n+i Is the coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
As a preferred implementation manner of this embodiment, the photoplethysmography needs to be filtered between step 1 and step 2. Specifically, a band-pass filter with a cut-off frequency of 0.1-4.2Hz may be used to filter the photoplethysmographic pulse wave.
As a preferred implementation manner of this embodiment, in order to reduce the interference, an autocorrelation process may be further performed on the respiration waveform between step 2 and step 3. The specific treatment method is as follows:
Figure BDA0002953816450000041
where m e [2000,3999], R represents the waveform data after autocorrelation, y represents the original respiratory waveform data, and m, n represents the position or index in the waveform data. The resulting autocorrelation waveform is shown in fig. 4.
Example 2
Referring to fig. 5, the present embodiment provides a sign monitor comprising: a blood oxygen saturation sensor and a processor, wherein the processor comprises a respiratory rate calculation module, the respiratory rate calculation module comprising:
a photoplethysmography obtaining unit 501, configured to obtain a photoplethysmography acquired by the blood oxygen saturation sensor;
a respiration waveform determining unit 502, configured to identify an amplitude and a coordinate value of each beat of the photoplethysmogram, and perform interpolation processing on the amplitude and the coordinate value to obtain a respiration waveform, where the respiration waveform is a waveform representing a relationship between the amplitude and the coordinate value;
a respiratory frequency calculation unit 503 for calculating a respiratory frequency based on the respiratory waveform, in particular according to F = F × n/(x) n+i -x i ) Calculating a respiratory frequency F, wherein F is a sampling frequency, which in this embodiment is 100,x n+i Is a coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
As a preferred implementation manner of this embodiment, the respiratory rate calculation module further includes:
and the photoelectric volume pulse wave filtering unit is used for filtering the photoelectric volume pulse wave. Specifically, a band-pass filter with a cut-off frequency of 0.1-4.2Hz can be used for filtering the photoplethysmographic pulse wave.
As a preferred implementation manner of this embodiment, the respiratory rate calculation module further includes:
and the autocorrelation processing unit is used for carrying out autocorrelation processing on the respiratory waveform.
In this embodiment, the physical sign monitor includes a blood oxygen analog front end, which is a chip for measuring blood oxygen saturation, and is used to drive the on-off timing and the light intensity of the red light and the infrared light in the blood oxygen saturation sensor, and convert the blood volume change signal into a digital signal. After the processor receives the digital signal, the respiratory frequency calculation module calculates the respiratory frequency according to the digital signal, and the screen displays the calculated respiratory frequency. In this embodiment, the blood oxygen saturation sensor is in a model of TJS2011J9, the blood oxygen simulation front end is in a model of AFE4490, the processor is a single chip microcomputer in a model of STM32H743, and the screen signal is KD035C-4-CTP-005.
The respiratory frequency measuring method and the physical sign monitor provided by the invention obtain respiratory waves based on the photoplethysmogram acquired by the blood oxygen saturation sensor. Compared with the method for measuring the respiratory frequency by using the chest impedance and the respiratory airflow method in the prior art, the method for measuring the respiratory frequency of the physical sign monitor does not need to add a part on the conventional physical sign monitor, not only increases the respiratory frequency measurement function of the physical sign monitor, but also ensures the convenience of the physical sign monitor, and realizes respiratory monitoring without increasing the cost.
In the present specification, the embodiments are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. For the system disclosed by the embodiment, the description is relatively simple because the system corresponds to the method disclosed by the embodiment, and the relevant points can be referred to the description of the method part.
The principle and the embodiment of the present invention are explained by applying specific examples, and the above description of the embodiments is only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the foregoing, the description is not to be taken in a limiting sense.

Claims (8)

1. A respiratory rate measurement method, characterized in that the respiratory rate measurement method comprises:
step 1: acquiring a photoplethysmogram acquired by a blood oxygen saturation sensor;
step 2: identifying the amplitude and the coordinate value of each beat of pulse of the photoplethysmography, and carrying out interpolation processing on the amplitude and the coordinate value to obtain a respiratory waveform, wherein the respiratory waveform is a waveform representing the relationship between the amplitude and the coordinate value;
and step 3: calculating a respiratory frequency based on the respiratory waveform;
between step 2 and step 3, further comprising: performing autocorrelation processing on the respiration waveform;
the specific processing mode of the autocorrelation processing is as follows:
Figure FDF0000018824040000011
wherein, m belongs to [2000,3999], R represents waveform data after autocorrelation, y represents original respiratory waveform data, and m and n represent positions in the waveform data, so as to obtain a waveform diagram after autocorrelation.
2. The respiratory rate measurement method according to claim 1, further comprising, between step 1 and step 2:
filtering the photoplethysmographic pulse wave.
3. The method for measuring respiratory rate according to claim 2, wherein the filtering the photoplethysmographic pulse wave specifically comprises:
and filtering the photoplethysmography by adopting a band-pass filter with the cut-off frequency of 0.1-4.2 Hz.
4. The method for measuring respiratory rate according to claim 1, wherein step 3 specifically comprises:
according to F = F x n/(x) n+i -x i ) Calculating a respiratory frequency F, wherein F is a sampling frequency x n+i Is the coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
5. A sign monitor, the sign monitor comprising: oxyhemoglobin saturation sensor and processor, characterized in that, the processor includes respiratory rate calculation module, respiratory rate calculation module includes:
the photoelectric volume pulse wave acquisition unit is used for acquiring the photoelectric volume pulse wave acquired by the blood oxygen saturation sensor;
the respiratory waveform determining unit is used for identifying the amplitude and the coordinate value of each beat of pulse of the photoplethysmography and carrying out interpolation processing on the amplitude and the coordinate value to obtain a respiratory waveform, wherein the respiratory waveform is a waveform representing the relationship between the amplitude and the coordinate value;
a respiratory frequency calculation unit for calculating a respiratory frequency based on the respiratory waveform;
the respiratory rate calculation module further comprises:
and the autocorrelation processing unit is used for carrying out autocorrelation processing on the respiratory waveform.
6. The sign monitor of claim 5, wherein the respiratory rate calculation module further comprises:
and the photoelectric volume pulse wave filtering unit is used for filtering the photoelectric volume pulse wave.
7. The sign monitor of claim 6, wherein the photoplethysmography filtering unit comprises:
and the photoelectric volume pulse wave filtering subunit is used for filtering the photoelectric volume pulse wave by adopting a band-pass filter with the cut-off frequency of 0.1-4.2 Hz.
8. The sign monitor of claim 5, wherein the respiratory rate calculation unit comprises:
a respiratory rate calculation subunit for calculating a respiratory rate according to F = F n/(x) n+i -x i ) The breathing frequency F is calculated and,wherein f is the sampling frequency, x n+i Is the coordinate value, x, corresponding to the n + i th peak value in the respiratory waveform i And the coordinate value is the coordinate value corresponding to the ith peak value in the respiratory waveform.
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