CN113005010A - Microbial fermentation tank - Google Patents

Microbial fermentation tank Download PDF

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Publication number
CN113005010A
CN113005010A CN202110426381.XA CN202110426381A CN113005010A CN 113005010 A CN113005010 A CN 113005010A CN 202110426381 A CN202110426381 A CN 202110426381A CN 113005010 A CN113005010 A CN 113005010A
Authority
CN
China
Prior art keywords
main shaft
air
stirring
air inlet
tank body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110426381.XA
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Chinese (zh)
Inventor
王晓凯
徐晓强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Zero One Life Technology Co ltd
Original Assignee
Shenzhen Zero One Life Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Zero One Life Technology Co ltd filed Critical Shenzhen Zero One Life Technology Co ltd
Priority to CN202110426381.XA priority Critical patent/CN113005010A/en
Publication of CN113005010A publication Critical patent/CN113005010A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • C12M27/04Stirrer or mobile mixing elements with introduction of gas through the stirrer or mixing element
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06Nozzles; Sprayers; Spargers; Diffusers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14Pressurized fluid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/20Heat exchange systems, e.g. heat jackets or outer envelopes the heat transfer medium being a gas

Abstract

The invention relates to a microbial fermentation tank which comprises a tank body, wherein a plurality of heating wires, a stirring shaft and a stirring shaft motor are arranged in the tank body; the stirring shaft comprises a main shaft, and a plurality of stirring support rods are arranged at the lower end of the main shaft; the upper end of the main shaft is provided with a sealed rotary air inlet joint, and the surface of the stirring support rod is provided with a plurality of air outlet holes; the tank body is also internally provided with a plurality of air inlet covers, an air exhaust fan is rotationally arranged in each air inlet cover, and the sealed rotary air inlet joint is connected with the plurality of air inlet covers through hard multi-way pipes; a transmission gear is coaxially fixed on the main shaft, and a driven gear is coaxially fixed on the exhaust fan; adopt single driving source to stir in, not only can be to upper portion air heating, simultaneously can also be with the leading-in material inside of the hot air in upper portion, leading-in air is the foaming come-up in the material, provides the air, has still promoted the removal stirring of material when making the heat more even, is favorable to the reproduction of microorganism.

Description

Microbial fermentation tank
Technical Field
The invention relates to the technical field of microbial fermentation tanks, in particular to a microbial fermentation tank.
Background
With the development of genetic engineering, more and more microbial strains are put into industrial production. In the existing microbial industrial production, a microbial fermentation tank is adopted for mass culture. Under the condition of proper environment, the microbe can continuously absorb nutrient substances, and can make metabolic activity according to its own metabolic mode, if the assimilation action is greater than the dissimilation action, the quantity of cytoplasm can be continuously increased, its volume can be increased, and the effective metabolic product can be continuously produced. The microorganism is in certain physical and chemical conditions, the growth and development are normal, and the propagation rate is high; if one or some environmental conditions change and exceed the range which can be adapted by living beings, the effect of inhibiting or killing the living bodies can be generated.
During the growth process of the microorganism, a large amount of metabolites or secondary metabolites are discharged, and the partial metabolites have certain influence on the continuous growth of the microorganism; meanwhile, gases such as oxygen, nitrogen and the like are needed in the growth process of the microorganisms, so that continuous stirring is needed in the culture process, the materials in the fermentation tank are continuously mixed, and the proportion and the temperature of all the materials are consistent.
The traditional stirring device used by the microbial fermentation tank adopts central stirring, the contact area is extremely limited, the consistency coordination of substances, air and temperature is difficult to carry out, and the breeding of microorganisms is not facilitated.
Disclosure of Invention
The technical problem to be solved by the present invention is to provide a microorganism fermentation tank, which addresses the above-mentioned drawbacks of the prior art.
The technical scheme adopted by the invention for solving the technical problems is as follows:
the microbial fermentation tank is constructed and comprises a tank body, wherein the upper end in the tank body is provided with a plurality of heating wires for heating air, a stirring shaft extending into a material and a stirring shaft motor for driving the stirring shaft motor to move; the stirring shaft comprises a longitudinal main shaft driven by the stirring shaft motor to rotate, and a plurality of stirring support rods are arranged at the lower end of the main shaft; the main shaft and the stirring support rod are both hollow and communicated, the upper end of the main shaft is provided with a sealed rotary air inlet joint communicated with the interior of the main shaft, and the surface of the stirring support rod is provided with a plurality of air outlet holes; the main shaft is rotatably arranged in the tank body, a plurality of air inlet covers which are covered on the heating wires in a one-to-one correspondence mode are further arranged in the tank body, an air suction fan is rotatably arranged in each air inlet cover, the sealed rotary air inlet joint is connected with the plurality of air inlet covers through hard multi-way pipes, and the air suction fan is used for discharging air in the air inlet covers into the multi-way pipes; the main shaft is coaxially fixed with a transmission gear, the exhaust fan is coaxially fixed with a driven gear, the driven gears are distributed around the periphery of the transmission gear and are all meshed with the transmission gear, and the gear ratio of the transmission gear to the driven gear is not less than 10: 1.
According to the microbial fermentation tank, the stirring support rods are longitudinally arranged on the main shaft and are not arranged right opposite to each other.
The microbial fermentation tank is characterized in that an installation frame is arranged in the tank body, and the main shaft is rotatably arranged on the installation frame.
The microbial fermentation tank provided by the invention is characterized in that the pumping fan is coaxially connected with the driven gear through a connecting shaft; the connecting shaft is rotatably arranged on the mounting frame; the air inlet cover is fixedly connected with the inner wall of the tank body.
According to the microbial fermentation tank, the mounting frame is further provided with a protective shell wrapping the transmission gear and the driven gear, and the protective shell is provided with a first sealing bearing corresponding to the main shaft and a second sealing bearing corresponding to the connecting shaft.
The microbial fermentation tank provided by the invention is characterized in that the stirring shaft motor drives the stirring shaft through the synchronous wheel assembly.
The microbial fermentation tank is characterized in that an air supercharger for regulating the positive pressure in the tank body is arranged on the tank body.
The invention relates to a microbial fermentation tank, wherein the upper end of the tank body is provided with a feeding hole and a feeding valve for controlling the opening and closing of the feeding hole; the lower extreme of jar body is provided with the discharge gate and controls its discharge valve who opens and close.
The invention has the beneficial effects that: when fermentation is carried out, the heating wires can be started to heat the upper hollow part in the tank body, the motor of the stirring shaft drives the stirring shaft to stir, the main shaft rotates and drives a plurality of driven gears to synchronously rotate through the transmission gear, a plurality of exhaust fans synchronously rotate to suck air heated by the heating wires in the air inlet cover into the multi-way pipe, the pressed hot air is blown out of the air outlet holes in the stirring support rods through the multi-way pipe, the rotary air inlet joint is sealed, the main shaft and the stirring support rods, the air is stirred by adopting a single driving source, the air at the upper part can be heated, the hot air at the upper part can be guided into the material, the stirring is carried out simultaneously, the guided air floats upwards in the material, air is provided, the heat is more uniform, the moving stirring of the material is promoted, the integral stirring effect is improved, and further, the material, The air and the temperature achieve the aim of consistency and coordination, and the propagation of microorganisms is facilitated.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be further described with reference to the accompanying drawings and embodiments, wherein the drawings in the following description are only part of the embodiments of the present invention, and for those skilled in the art, other drawings can be obtained without inventive efforts according to the accompanying drawings:
FIG. 1 is a schematic view of a microorganism fermenter according to a preferred embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without inventive step, are within the scope of the present invention.
The microbial fermentation tank of the preferred embodiment of the invention, as shown in figure 1, comprises a tank body 1, wherein the upper end in the tank body 1 is provided with a plurality of heating wires 12 for heating air, a stirring shaft 13 extending into the material and a stirring shaft motor 14 for driving the stirring shaft motor to move; the stirring shaft 13 comprises a longitudinal main shaft 130 driven by a stirring shaft motor to rotate, and the lower end of the main shaft is provided with a plurality of stirring support rods 131; the main shaft 130 and the stirring support rod 131 are both hollow and communicated, the upper end of the main shaft 130 is provided with a sealed rotary air inlet joint 1300 communicated with the interior of the main shaft, and the surface of the stirring support rod 131 is provided with a plurality of air outlet holes 1310; the main shaft 130 is rotatably arranged in the tank body 1, a plurality of air inlet hoods 15 which are covered on the heating wires 12 in a one-to-one correspondence manner are further arranged in the tank body 1, air suction fans 150 are rotatably arranged in the air inlet hoods 15, the sealed rotary air inlet joint 1300 is connected with the plurality of air inlet hoods 15 through hard multi-way pipes 1301, and the air suction fans 150 are used for discharging air in the air inlet hoods 15 into the multi-way pipes 1301; a transmission gear 17 is coaxially fixed on the main shaft 130, driven gears 18 are coaxially fixed on the suction fan 150, a plurality of driven gears 18 are circumferentially distributed on the periphery of the transmission gear 17 and are all meshed with the transmission gear 17, and the ratio of the number of the transmission gear 17 to the number of the driven gears 18 is not less than 10: 1;
when fermentation is carried out, the heating wires can be started to heat the upper hollow part in the tank body, the motor of the stirring shaft drives the stirring shaft to stir, the main shaft rotates and drives a plurality of driven gears to synchronously rotate through the transmission gear, a plurality of exhaust fans synchronously rotate to suck air heated by the heating wires in the air inlet cover into the multi-way pipe, the pressed hot air is blown out of the air outlet holes in the stirring support rods through the multi-way pipe, the rotary air inlet joint is sealed, the main shaft and the stirring support rods, the air is stirred by adopting a single driving source, the air at the upper part can be heated, the hot air at the upper part can be guided into the material, the stirring is carried out simultaneously, the guided air floats upwards in the material, air is provided, the heat is more uniform, the moving stirring of the material is promoted, the integral stirring effect is improved, and further, the material, The air and the temperature achieve the aim of consistency and coordination, which is beneficial to the propagation of microorganisms;
in addition, the air inlet hood 15 is used not only to quickly concentrate and reflect the heat of the heating wire 12, but also to provide protection to the heating wire 12 during feeding.
Preferably, the plurality of stirring struts 131 are longitudinally arranged on the main shaft 130 and are not arranged right opposite to each other; the gas outlet is more dispersed, and the condition that the excessive gas at the local position causes the splashing of the material during stirring is avoided.
Preferably, a mounting rack 19 is arranged in the tank body 1, and the main shaft 130 is rotatably arranged on the mounting rack 19; the suction fan 150 is coaxially connected with the driven gear 18 through a connecting shaft 180; the connecting shaft 180 is rotatably arranged on the mounting rack 19; the air inlet cover 15 is fixedly connected with the inner wall of the tank body 1; reasonable and compact structure and good stability.
Preferably, the mounting bracket 19 is further provided with a protective shell 190 wrapped outside the transmission gear 17 and the driven gear 18, and the protective shell 190 is provided with a first sealed bearing 1900 corresponding to the main shaft 130 and a second sealed bearing 1901 corresponding to the connecting shaft 180; the gear set part is protected conveniently, and the structure is reasonable and compact.
Preferably, the mixer shaft motor 14 drives the mixer shaft 13 via the synchronizing wheel assembly 140;
preferably, the device also comprises an air supercharger 2, wherein the upper end of the tank body 1 is provided with a feeding hole 10 and a feeding valve 100 for controlling the opening and closing of the feeding hole; the lower end of the tank body 1 is provided with a discharge port 11 and a discharge valve 110 for controlling the opening and closing of the discharge port.
It will be understood that modifications and variations can be made by persons skilled in the art in light of the above teachings and all such modifications and variations are intended to be included within the scope of the invention as defined in the appended claims.

Claims (8)

1. A microbial fermentation tank is characterized by comprising a tank body, wherein the upper end in the tank body is provided with a plurality of heating wires for heating air, a stirring shaft extending into a material and a stirring shaft motor for driving the stirring shaft motor to move; the stirring shaft comprises a longitudinal main shaft driven by the stirring shaft motor to rotate, and a plurality of stirring support rods are arranged at the lower end of the main shaft; the main shaft and the stirring support rod are both hollow and communicated, the upper end of the main shaft is provided with a sealed rotary air inlet joint communicated with the interior of the main shaft, and the surface of the stirring support rod is provided with a plurality of air outlet holes; the main shaft is rotatably arranged in the tank body, a plurality of air inlet covers which are covered on the heating wires in a one-to-one correspondence mode are further arranged in the tank body, an air suction fan is rotatably arranged in each air inlet cover, the sealed rotary air inlet joint is connected with the plurality of air inlet covers through hard multi-way pipes, and the air suction fan is used for discharging air in the air inlet covers into the multi-way pipes; the main shaft is coaxially fixed with a transmission gear, the exhaust fan is coaxially fixed with a driven gear, the driven gears are distributed around the periphery of the transmission gear and are all meshed with the transmission gear, and the gear ratio of the transmission gear to the driven gear is not less than 10: 1.
2. The microbial fermentation tank of claim 1, wherein a plurality of the stirring struts are longitudinally arranged on the main shaft and are not arranged in an opposite manner.
3. The microbial fermentation tank of claim 1 or 2, wherein a mounting frame is arranged in the tank body, and the main shaft is rotatably arranged on the mounting frame.
4. The microbial fermentation tank of claim 3, wherein the suction fan is coaxially connected with the driven gear through a connecting shaft; the connecting shaft is rotatably arranged on the mounting frame; the air inlet cover is fixedly connected with the inner wall of the tank body.
5. The microbial fermentation tank of claim 4, wherein a protective shell is further arranged on the mounting frame and wraps the transmission gear and the driven gear, and a first sealing bearing corresponding to the main shaft and a second sealing bearing corresponding to the connecting shaft are arranged on the protective shell.
6. The microbial fermenter of claim 4, wherein the agitator shaft motor drives the agitator shaft via a synchronizing wheel assembly.
7. The microbial fermentation tank of claim 4, wherein the tank body is provided with an air booster for regulating the internal positive pressure.
8. The microbial fermentation tank of claim 4, wherein the upper end of the tank body is provided with a feeding hole and a feeding valve for controlling the opening and the closing of the feeding hole; the lower extreme of jar body is provided with the discharge gate and controls its discharge valve who opens and close.
CN202110426381.XA 2021-04-20 2021-04-20 Microbial fermentation tank Pending CN113005010A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110426381.XA CN113005010A (en) 2021-04-20 2021-04-20 Microbial fermentation tank

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110426381.XA CN113005010A (en) 2021-04-20 2021-04-20 Microbial fermentation tank

Publications (1)

Publication Number Publication Date
CN113005010A true CN113005010A (en) 2021-06-22

Family

ID=76388871

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110426381.XA Pending CN113005010A (en) 2021-04-20 2021-04-20 Microbial fermentation tank

Country Status (1)

Country Link
CN (1) CN113005010A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010069477A (en) * 2008-08-22 2010-04-02 Chubu Shiryo Kk Fermentation apparatus for food residue
CN209144132U (en) * 2018-10-31 2019-07-23 北京康缘益生生物科技有限公司 A kind of fermentor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010069477A (en) * 2008-08-22 2010-04-02 Chubu Shiryo Kk Fermentation apparatus for food residue
CN209144132U (en) * 2018-10-31 2019-07-23 北京康缘益生生物科技有限公司 A kind of fermentor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
王书堂: "轴芯通气喷气助力式搅拌发酵罐简析", 《医药工程设计》 *
陈余: "浅谈发酵罐的选型设计", 《化学工程与装备》 *

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Application publication date: 20210622

RJ01 Rejection of invention patent application after publication