CN112957386B - Processing method of traditional Chinese medicine decoction pieces - Google Patents
Processing method of traditional Chinese medicine decoction pieces Download PDFInfo
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Abstract
The invention provides a processing method of traditional Chinese medicine decoction pieces, which comprises the following steps: s1: cleaning the dug bighead atractylodes rhizome, slicing and drying in the air; s2: adding water into fresh Chinese yam to form slurry; s3: soaking Atractylodis rhizoma in the soaking solution, taking out, and air drying; s4: cleaning adjuvants, repeatedly decocting in a frying pan for 2-3 times, mixing, and filtering to obtain concentrated decoction; s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2-3h to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices; s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into desired Chinese medicinal decoction pieces; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 60-100 parts of largehead atractylodes rhizome, 20-30 parts of Chinese yam, 10-25 parts of ginseng and pilose antler, 10-15 parts of lily and 5-10 parts of hawthorn. The invention provides a processing method of traditional Chinese medicine decoction pieces with good drug effects of promoting urination, tonifying spleen and replenishing qi.
Description
Technical Field
The invention relates to the technical field of preparation of traditional Chinese medicine decoction pieces, in particular to a processing method of traditional Chinese medicine decoction pieces.
Background
The Chinese pharmacopoeia 2010 edition has definite definition of the Chinese herbal pieces: the decoction pieces refer to the prescription drugs which can be directly used in the traditional Chinese medicine clinical or preparation production after being processed. The essence of the Chinese medicinal decoction pieces is to highlight the legal characteristics of the Chinese medicinal decoction pieces as prescription medicines, and the Chinese medicinal materials are definitely specified to be prepared into corresponding Chinese medicinal decoction pieces through proper processing and can be used as raw material medicines for preparing Chinese medicinal clinical prescription medicines or Chinese medicinal preparations. Therefore, for the traditional Chinese medicine decoction pieces, the processing method is very important for the use of the medicinal materials.
As one of the unique traditional pharmaceutical technologies in China, the traditional Chinese medicine processing technology is the dominant industry with the most proprietary intellectual property rights and is also an important way for discovering new medicines. The traditional Chinese medicinal materials are giant complex organism supermolecules, and the effective component groups of the traditional Chinese medicinal materials are guest micromolecules and are also used as imprinting templates; the water-insoluble ineffective component is medicine residue which is a tissue substance and also a main molecule. The effect of the theory of mesomedicine can be explained by the supramolecular chemistry. The principle of the processing technology is that the medicine properties of the traditional Chinese medicinal materials are influenced by the organic combination of various aspects such as chemistry, biology, clinical medicine and the like. The rhizoma atractylodis macrocephalae is warm in nature, sweet and bitter in taste and has good diuretic effect, but the processing method in the prior art ensures that the functional components of the rhizoma atractylodis macrocephalae decoction pieces are relatively less, and the medicinal effects of promoting urination, tonifying spleen and replenishing qi are to be improved.
Therefore, the processing method of the traditional Chinese medicine decoction pieces with good effects of promoting urination, tonifying spleen and replenishing qi needs to be researched.
Disclosure of Invention
The invention aims to provide a processing method of traditional Chinese medicine decoction pieces with good effects of promoting urination, tonifying spleen and replenishing qi.
The technical purpose of the invention is realized by the following technical scheme: a processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug bighead atractylodes rhizome in a cleaning cylinder, selecting bighead atractylodes rhizome slices with approximate sizes, and airing;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking Atractylodis rhizoma in the soaking solution for 1-2 hr, taking out Atractylodis rhizoma, and air drying;
s4: cleaning the auxiliary materials except for the rhizoma atractylodis macrocephalae and the rhizoma dioscoreae, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting for 2-3h at 80-90 ℃, filtering the traditional Chinese medicine residues, repeatedly decocting the traditional Chinese medicine residues for 2-3 times, combining and filtering to obtain a decoction concentrated solution;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2-3h to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into desired Chinese medicinal decoction pieces; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 60-100 parts of largehead atractylodes rhizome, 20-30 parts of Chinese yam, 10-25 parts of ginseng and pilose antler, 10-15 parts of lily and 5-10 parts of hawthorn.
Furthermore, the traditional Chinese medicine decoction pieces also comprise 5-10 parts of long pepper.
Furthermore, the traditional Chinese medicine decoction pieces also comprise 3-5 parts of Lupus lupulus.
Furthermore, the traditional Chinese medicine decoction pieces also comprise 3-5 parts of caraway fruit.
Further, the soaking solution in the step S3 includes the following components in parts by weight: 10-15 parts of pectinase, 5-10 parts of cellulase and 5-10 parts of beta-glucosidase.
Further, the relative concentration of the decoction concentrate in the step S4 is 0.6-0.8.
Further, in step S1, the cut rhizoma Atractylodis Macrocephalae has a length of 3-5cm and a thickness of 5-10 mm.
Further, the water content of the herbal pieces prepared in step S6 is 10-15%.
The invention has the beneficial effects that:
1. the processing method of the traditional Chinese medicine decoction pieces is a compatibility processing method of monarch and minister compatibility, the main material is the bighead atractylodes rhizome, a plurality of traditional Chinese medicine materials such as ginseng antler, lily, hawthorn and the like are decocted to prepare medicine concentrated juice which is decocted together with the bighead atractylodes rhizome slices, and effective active ingredients of the medicine concentrated juice interact and mutually influence to finally form the functional bighead atractylodes rhizome traditional Chinese medicine decoction pieces with good diuresis effect and spleen tonifying and qi replenishing functions.
2. The Chinese yam rhizome decoction takes the bighead atractylodes rhizome which is warm in nature and sweet in taste, strengthens the spleen, replenishes qi, eliminates dampness and promotes diuresis as a monarch drug, and tonifies the spleen, nourishes the stomach, promotes the production of body fluid, benefits the lung, tonifies the kidney and astringes the essence as a minister drug; patients with heart disease and hypertension usually need to promote the production of body fluid and induce diuresis to relieve the pressure in blood and effectively reduce the heart burden, the Luoyangye clove has the effects of lowering qi, warming the middle-jiao and warming the kidney, the Long Pepper has the effects of warming the middle-jiao and invigorating the stomach, dispelling cold and relieving pain, and the two cooperate with the Atractylodes macrocephala and the Chinese yam to play the effects of tonifying the kidney, promoting the production of body fluid, tonifying qi and inducing diuresis.
3. The traditional Chinese medicine raw materials are also added with the caraway, the caraway has a slightly pungent flavor and warm nature, and enters kidney and stomach channels; the caraway fruit contains volatile oil which is called caraway oil and is used as a main active ingredient of the caraway, the caraway oil contains carvone which has the functions of relieving asthma, relieving cough and promoting urination, and the caraway fruit is prepared by adopting a decoction processing step to mix the effective diuretic substances with the effective active ingredients of the largehead atractylodes rhizome and attach the effective diuretic active substances together into the largehead atractylodes rhizome drinking tablet, so that the synergistic effect of the largehead atractylodes rhizome drinking tablet on promoting urination is effectively improved.
4. The Chinese yam provided by the invention is used as a ministerial drug, a fresh pulping mode is adopted, the Chinese yam cells can be rapidly crushed in a mechanical mode, the active ingredients such as mucin, amylase, saponin, free amino acid, polyphenol oxidase and choline rapidly overflow, and the Chinese yam is decocted with other auxiliary materials, so that the outflow efficiency of the active drug ingredients is effectively improved, the content of the active ingredients in a decoction concentrated solution is improved, and the diuretic effect of the subsequent rhizoma atractylodis macrocephalae decoction pieces is improved.
5. According to the invention, the rhizoma atractylodis macrocephalae is soaked in the soaking solution, pectinase, cellulase and beta-glucosidase are added into the soaking solution, colloid among plant cells is decomposed under the action of the pectinase, so that the rhizoma atractylodis macrocephalae cells are released from plant tissues, then cellulose of the rhizoma atractylodis macrocephalae cells is degraded by the cellulase and the beta-glucosidase, atractylenolide in the rhizoma atractylodis macrocephalae can be rapidly released in the subsequent decoction process, a chemical bond connection relation is formed between the atractylenolide and effective components of dioscorea opposita, such as saponin, free amino acid and the like, effective chemical substances are stably connected and fixed in the rhizoma atractylodis macrocephalae decoction pieces, the content of the effective components of the processed rhizoma atractylodis macrocephalae is increased, and the diuretic medicinal effect of the subsequent rhizoma atractylodis macrocephalae decoction pieces is improved.
Detailed Description
The technical solution of the present invention will be clearly and completely described below with reference to specific embodiments. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
Example 1
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 3cm, and the thickness of the rhizoma Atractylodis slice is 5 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 10 parts of pectinase, 5 parts of cellulase and 5 parts of beta-glucosidase for 1 hour, and then fishing out the white atractylodes rhizome and airing;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 80 ℃ for 2 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2 times, combining and filtering to obtain a decoction concentrated solution with the relative concentration of 0.8;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 10%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 60 parts of largehead atractylodes rhizome, 20 parts of Chinese yam, 10 parts of ginseng antler, 10 parts of lily, 5 parts of hawthorn, 5 parts of long pepper, 3 parts of Lupinus pinnatifida and 3 parts of Carum carvi fruit.
Example 2
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 5cm, and the thickness of the rhizoma Atractylodis slice is 10 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in soaking liquid containing 15 parts of pectinase, 10 parts of cellulase and 10 parts of beta-glucosidase for 2 hours, and then fishing out the white atractylodes rhizome and airing;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting for 3 hours at 90 ℃, filtering the decoction dregs, repeatedly decocting the decoction dregs for 3 times, combining and filtering to obtain a decoction concentrated solution with the relative concentration of 0.6;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 3 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 15%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 100 parts of largehead atractylodes rhizome, 30 parts of Chinese yam, 25 parts of ginseng antler, 15 parts of lily, 10 parts of hawthorn, 10 parts of long pepper, 5 parts of Lupinus pinnatifida and 5 parts of Carum carvi fruit.
Example 3
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 85 ℃ for 2.5 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2.5 times, merging and filtering to obtain a decoction concentrated solution with the relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 8 parts of long pepper, 4 parts of Lupinus pinnatifida and 4 parts of Carum carvi fruit.
Example 4
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 85 ℃ for 2.5 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2.5 times, merging and filtering to obtain a decoction concentrated solution with the relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 4 parts of lupulus and 4 parts of caraway fruit.
Example 5
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 85 ℃ for 2.5 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2.5 times, merging and filtering to obtain a decoction concentrated solution with the relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 8 parts of long pepper, and 4 parts of caraway fruit.
Example 6
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s4: cleaning adjuvants except Atractylodis rhizoma and rhizoma Dioscoreae, decocting in water in a decocting pan, decocting at 85 deg.C for 2.5 hr, filtering to obtain residue, decocting the residue for 2.5 times, mixing filtrates to obtain decoction concentrate with relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 8 parts of long pepper, and 4 parts of Lupinus pinnatifida.
Example 7
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s4: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 85 ℃ for 2.5 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2.5 times, merging and filtering to obtain a decoction concentrated solution with the relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng and pilose antler, 13 parts of lily and 8 parts of hawthorn.
Example 8
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: cleaning fresh Chinese yam, putting into a pulping machine, and adding water to form slurry;
s3: soaking the white atractylodes rhizome in 29 parts of water for 1.5h, taking out the white atractylodes rhizome and drying the white atractylodes rhizome in the air;
s4: cleaning adjuvants except Atractylodis rhizoma and rhizoma Dioscoreae, decocting in water in a decocting pan, decocting at 85 deg.C for 2.5 hr, filtering to obtain residue, decocting the residue for 2.5 times, mixing filtrates to obtain decoction concentrate with relative concentration of 0.7;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 8 parts of long pepper, 4 parts of Lupinus pinnatifida and 4 parts of Carum carvi fruit.
Example 9
A processing method of traditional Chinese medicine decoction pieces comprises the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 4cm, and the thickness of the rhizoma Atractylodis slice is 8 mm;
s2: soaking the white atractylodes rhizome in a soaking solution containing 13 parts of pectinase, 8 parts of cellulase and 8 parts of beta-glucosidase for 1.5h, and then fishing out the white atractylodes rhizome and drying the white atractylodes rhizome;
s3: cleaning the auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting the auxiliary materials into a decocting pot, adding water for decocting, decocting at 85 ℃ for 2.5 hours, filtering the decoction dregs, repeatedly decocting the decoction dregs for 2.5 times, merging and filtering to obtain a decoction concentrated solution with the relative concentration of 0.7;
s4: washing and cutting Chinese yam, physically and uniformly mixing the decoction concentrated solution obtained in the step S4 and the sliced white atractylodes rhizome, and decocting in a decocting pot for 2.5 hours to collect juice to obtain the sliced white atractylodes rhizome after decoction;
s5: heating with fire in a pan, spreading testa Tritici, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, parching, taking out, sieving to remove testa Tritici, air drying, and making into Chinese medicinal decoction pieces with water content of 13%; the traditional Chinese medicine decoction pieces comprise the following components in parts by weight: comprises 80 parts of largehead atractylodes rhizome, 25 parts of Chinese yam, 15 parts of ginseng antler, 13 parts of lily, 8 parts of hawthorn, 8 parts of long pepper, 4 parts of Lupinus pinnatifida and 4 parts of Carum carvi fruit.
The test method comprises the following steps:
screening rats by Aston method, placing rats in metabolic cage for adaptation for 3d, after fasting for 18h, according to 2.5mL (100g)-1And (3) feeding gastric lavage deionized water in a dose, collecting urine for 2 hours, and obtaining qualified rats with the urination quality being more than 40% of the mass of the gastric lavage deionized water.
90 qualified rats were selected and divided into 10 per group according to examples 1-9. The preparation is administered by intragastric administration according to the specified dosage by adopting a metabolism cage method for 9d continuously. Fasting before the last administration for 24h without water prohibition, 5mL (100g) for each group-1The animal extracellular fluid can be increased by intragastric administration of 0.9% sodium chloride solution, and the retention state of sodium hydrate can be simulated. After 20min, 1mL (100g)-1The doses were gavaged and the blank group given the same volume of water. After administration, urine in the bladder was drained by lightly pressing the lower abdomen of the rats, then placed in a metabolism cage, urine was collected 1 time every 3 hours for 2 times in total, and urine in the bladder was drained by lightly pressing the lower abdomen of the rats before the last collection, and the urine volume in 6 hours after administration was recorded for each group of rats. The room temperature is preferably controlled to be (20 +/-1) ° C.
Decocting the Chinese medicinal decoction pieces prepared in examples 1-9 with water according to the common decoction method of Chinese medicinal materials in SZDBZ47-2011 decoction specification to obtain water decoction, and collecting 1.50g/kg-1The dosage of the composition is fed to rats, and the urine volume of the rats for 3h and 3-6 h is collected according to the method, and the result is shown in the following table 1:
TABLE 1 results of diuresis of rats by decoction of herbal pieces in each example
| DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION | 3h（ml） | 6h（ml） | Total amount (ml) |
| Example 1 | 15.74 | 5.17 | 20.91 |
| Example 2 | 20.23 | 6.34 | 26.57 |
| Example 3 | 18.62 | 5.72 | 24.34 |
| Example 4 | 12.17 | 3.45 | 15.62 |
| Example 5 | 11.75 | 3.21 | 14.96 |
| Example 6 | 12.73 | 3.51 | 16.24 |
| Example 7 | 7.86 | 2.12 | 9.98 |
| Example 8 | 12.31 | 3.04 | 15.35 |
| Example 9 | 13.24 | 3.12 | 16.36 |
The principles and embodiments of the present invention are explained herein using specific examples, which are set forth only to help understand the method and its core ideas of the present invention. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.
Claims (1)
1. The processing method of the traditional Chinese medicine decoction pieces is characterized by comprising the following steps:
s1: cleaning the dug rhizoma Atractylodis Macrocephalae in a cleaning cylinder, selecting rhizoma Atractylodis Macrocephalae slices with approximate size, and air drying, wherein the length of the rhizoma Atractylodis slice is 3-5cm, and the thickness of the rhizoma Atractylodis slice is 5-10 mm;
s2: cleaning fresh rhizoma Dioscoreae, and adding water into a pulping machine to obtain slurry;
s3: soaking the white atractylodes rhizome in a soaking solution for 1-2h, taking out the white atractylodes rhizome and airing, wherein the soaking solution comprises the following components in parts by weight: 10-15 parts of pectinase, 5-10 parts of cellulase and 5-10 parts of beta-glucosidase;
s4: cleaning auxiliary materials except for the bighead atractylodes rhizome and the Chinese yam, putting ginseng antler, lily, hawthorn, long pepper extract, lupulus and caraway fruit into a decocting pot, adding water for decocting, decocting for 2-3h at 80-90 ℃, filtering traditional Chinese medicine residues, repeatedly decocting the residues for 2-3 times, combining and filtering to obtain decoction concentrated solution, wherein the relative concentration of the decoction concentrated solution is 0.6-0.8;
s5: physically and uniformly mixing the rhizoma dioscoreae slurry beaten in the step S2, the decoction concentrated solution obtained in the step S4 and the rhizoma atractylodis macrocephalae slices, and decocting in a decocting pot for 2-3h to collect juice to obtain the decocted rhizoma atractylodis macrocephalae slices;
s6: heating with fire in a pan, spreading wheat bran, adding the decocted Atractylodis rhizoma slice prepared in step S5 when smoking, continuously parching, taking out, sieving to remove wheat bran, air drying, and making into Chinese medicinal decoction pieces with water content of 10-15%; the weight parts of the bighead atractylodes rhizome, the Chinese yam and the auxiliary materials are as follows: 60-100 parts of bighead atractylodes rhizome, 20-30 parts of Chinese yam, 10-25 parts of ginseng antler, 10-15 parts of lily, 5-10 parts of hawthorn, 5-10 parts of long pepper, 3-5 parts of Lupus lupulus and 3-5 parts of Carum carvi fruit.
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