CN112932483A - Sodium citrate anticoagulation tube with function of detecting micro-clots - Google Patents
Sodium citrate anticoagulation tube with function of detecting micro-clots Download PDFInfo
- Publication number
- CN112932483A CN112932483A CN202110145154.XA CN202110145154A CN112932483A CN 112932483 A CN112932483 A CN 112932483A CN 202110145154 A CN202110145154 A CN 202110145154A CN 112932483 A CN112932483 A CN 112932483A
- Authority
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- China
- Prior art keywords
- negative pressure
- vacuum negative
- pipe body
- pressure pipe
- sodium citrate
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000010100 anticoagulation Effects 0.000 title claims abstract description 21
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 title claims abstract description 21
- 239000001509 sodium citrate Substances 0.000 title claims abstract description 21
- 238000007789 sealing Methods 0.000 claims abstract description 30
- 239000003146 anticoagulant agent Substances 0.000 claims abstract description 6
- 229940127219 anticoagulant drug Drugs 0.000 claims abstract description 5
- 230000001681 protective effect Effects 0.000 claims description 10
- 229920005549 butyl rubber Polymers 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 229920003023 plastic Polymers 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 4
- 238000012360 testing method Methods 0.000 description 12
- 230000023555 blood coagulation Effects 0.000 description 10
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 208000007536 Thrombosis Diseases 0.000 description 3
- 230000004520 agglutination Effects 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000003908 quality control method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 238000001467 acupuncture Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/02—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to the field of medical instruments, in particular to a sodium citrate anticoagulation tube with a function of detecting tiny clots, which comprises: one end of the vacuum negative pressure pipe body is a U-shaped closed end, the other end of the vacuum negative pressure pipe body is provided with an opening, and a sodium citrate anticoagulant is arranged in the vacuum negative pressure pipe body; the sealing plug is in sealing fit with the opening of the vacuum negative pressure pipe body; the filter screen, the filter screen is followed the inside cross-section of vacuum negative pressure body sets up, the filter screen all around with the inside wall of vacuum negative pressure body closely laminates. The invention can quickly find and identify the tiny clot through the built-in filter screen, avoids the error of the detection result caused by the tiny clot, saves the cost and improves the detection quality.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a sodium citrate anticoagulation tube with a function of detecting micro-clots.
Background
The blood coagulation function test has important clinical application values for various thrombotic diseases, examination and prediction before thrombus, evaluation of easy-to-tie disease, experimental diagnosis of DIC, medication guidance and prognosis estimation of various anticoagulation treatment patients and the like. At present, a blood collection tube for blood coagulation function test generally uses a 3.2% sodium citrate anticoagulation tube, blood samples are collected and then are rapidly and uniformly mixed with the anticoagulation agent, and then plasma is separated for relevant blood coagulation index test. However, in actual operation, factors such as the position of the punctured blood vessel and the skill level of the operation of the puncturing personnel often cause that the blood flows into the vacuum negative pressure anticoagulation tube difficultly or cannot be mixed uniformly in time to cause blood agglutination in different degrees. Big blood clot just can discover through rocking the anti-coagulation pipe of vacuum negative pressure, however, little blood agglutination (piece) is hardly found through simply rocking anti-coagulation pipe, often suspects blood through the artifical judgement of testing result when having little agglutination (piece), just can discover through manual filtration or stirring rod stirring etc. both extravagant reagent, waste time have reduced work efficiency again, have also increased sample treatment personnel's work load, influence out the result of blood coagulation function test. Therefore, there is a need for a vacuum negative anticoagulation tube capable of rapidly identifying micro-clots.
Disclosure of Invention
The invention provides a sodium citrate anticoagulation tube with a function of detecting micro clots, which can quickly find and identify the micro clots through a built-in filter screen, avoid detection result errors caused by the micro clots, save cost and improve detection quality.
In order to achieve the purpose, the invention provides the following technical scheme: a sodium citrate anticoagulation tube with the function of detecting micro-clots, which comprises: one end of the vacuum negative pressure pipe body is a U-shaped closed end, the other end of the vacuum negative pressure pipe body is provided with an opening, and a sodium citrate anticoagulant is arranged in the vacuum negative pressure pipe body; the sealing plug is in sealing fit with the opening of the vacuum negative pressure pipe body; the filter screen, the filter screen is followed the inside cross-section of vacuum negative pressure body sets up, the filter screen all around with the inside wall of vacuum negative pressure body closely laminates.
Preferably, the vacuum negative pressure pipe body is integrally formed by PET plastics.
Preferably, the sealing plug is made of butyl rubber, and the sealing plug has a groove in the center of one end located outside the vacuum negative pressure pipe body.
Preferably, the distance between the filter screen and the sealing plug is 8-12 mm; the aperture of the filter screen is 1.8-2.2 mm.
Preferably, the center of the filter screen is fixedly connected with one end, corresponding to the inside of the vacuum negative pressure pipe body, of the sealing plug through a connecting column, and the connecting column is arranged in a zigzag manner.
Preferably, the inner wall of the opening end of the vacuum negative pressure pipe body is provided with a locking thread for fixing the sealing plug.
Preferably, the vacuum negative pressure pipe further comprises a protective cover, wherein the protective cover is embedded outside the sealing plug and is in threaded connection with the outer wall of the opening end of the vacuum negative pressure pipe body; the protective cover is provided with a through hole corresponding to the groove.
Preferably, the bottom end of the groove is provided with a conical bulge.
The invention has the beneficial effects that: vacuum negative pressure body adds a filter screen more than ordinary heparin tube, can be fast and the unqualified sample of efficient discernment, when various reasons and the blood that leads to gathering has little clot, reverse behind the vacuum negative pressure heparin tube fibrin silk can adhere in the filter screen, medical personnel can in time discover and take corrective action, thereby stop unqualified sample, and the work efficiency is improved, it is extravagant to have reduced follow-up reagent, and the quality of clinical blood coagulation test is improved simultaneously, promote the precision and the accuracy of blood coagulation test, eliminate blood sample unqualified and lead to the inspection result error, quality control before the analysis has important clinical meaning, can fill in the blank in blood coagulation test sample management, sample pretreatment operation process.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a sectional view showing the overall structure of the present invention.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it is to be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
according to the figure 1, the sodium citrate anticoagulation tube with the function of detecting the micro-clots comprises: one end of the vacuum negative pressure pipe body 1 is a U-shaped closed end, the other end of the vacuum negative pressure pipe body 1 is provided with an opening, and a sodium citrate anticoagulant 2 is arranged in the vacuum negative pressure pipe body 1; the sealing plug 3 is hermetically matched in the opening of the vacuum negative pressure pipe body 1; the filter screen 4, the filter screen 4 is followed the inside cross-section setting of vacuum negative pressure body 1, filter screen 4 all around with the inside wall of vacuum negative pressure body 1 closely laminates. The vacuum negative pressure pipe body 1 is integrally formed by PET plastics. The sealing plug 3 is made of butyl rubber, and the sealing plug 3 has a groove 5 in the center of one end located outside the vacuum negative pressure pipe body 1. The distance between the filter screen 4 and the sealing plug 3 is 8-12 mm; the aperture of the filter screen 4 is 1.8 to 2.2 mm.
In the above arrangement, 0.2ml of 3.2% sodium citrate anticoagulant 2 is injected into the vacuum negative pressure tube body 1 in advance and sealed by the sealing plug 3, wherein the groove 5 at the top end of the sealing plug 3 is convenient for the puncture needle to enter, and the filter screen 4 can quickly and efficiently identify unqualified samples, when blood collected due to various reasons has tiny clots, fibrin filaments can be adhered to the filter screen 4 after the vacuum negative pressure tube body 1 is reversed, medical personnel can find and take corrective measures in time, thereby avoiding unqualified samples, improving the working efficiency, reducing the subsequent reagent waste, simultaneously improving the quality of clinical blood coagulation test, improving the precision and accuracy of the blood coagulation test, eliminating the error of test results caused by unqualified blood samples, has important clinical significance on quality control before analysis, and can fill the blank in the operation processes of blood coagulation test specimen management and sample pretreatment.
Example two:
the center of the filter screen 4 is fixedly connected with one end of the sealing plug 3 corresponding to the inside of the vacuum negative pressure pipe body 1 through a connecting column 6. The inner wall of the opening end of the vacuum negative pressure pipe body 1 is provided with a locking thread 7 for fixing the sealing plug 3. The vacuum negative pressure pipe further comprises a protective cover 8, wherein the protective cover 8 is embedded outside the sealing plug 3 and is in threaded connection with the outer wall of the opening end of the vacuum negative pressure pipe body 1; the protective cover 8 is provided with a through hole corresponding to the groove 5.
In the above arrangement, the anti-loosening thread 7 not only increases the friction force between the sealing plug 3 and the opening end of the vacuum negative pressure pipe body 1, but also improves the sealing effect, and the protective cover 8 not only can fix the sealing plug 3, but also can facilitate the automatic operation of the mechanical equipment for rotating the protective cover 8.
Example three:
the connecting column 6 is arranged in a zigzag mode, and a conical bulge 9 is arranged at the bottom end of the groove 5.
Through the aforesaid setting, when spliced pole 6 that the tortuous set up is invertd again or is rocked vacuum negative pressure body 1, play the cushioning effect, avoid supplementary coagulum on filter screen 4 to drop and the judgement that causes is out of alignment, and conical arch 9, effectual protection spliced pole 6, when avoiding the acupuncture, run through all sorts of drawbacks that spliced pole 6 leads to because of the syringe needle.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (8)
1. A sodium citrate anticoagulation tube with the function of detecting micro-clots is characterized by comprising:
one end of the vacuum negative pressure pipe body is a U-shaped closed end, the other end of the vacuum negative pressure pipe body is provided with an opening, and a sodium citrate anticoagulant is arranged in the vacuum negative pressure pipe body;
the sealing plug is in sealing fit with the opening of the vacuum negative pressure pipe body;
the filter screen, the filter screen is followed the inside cross-section of vacuum negative pressure body sets up, the filter screen all around with the inside wall of vacuum negative pressure body closely laminates.
2. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 1, characterized in that: the vacuum negative pressure pipe body is integrally formed by PET plastics.
3. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 2, characterized in that: the sealing plug is made of butyl rubber, and a groove is formed in the center of one end, located outside the vacuum negative pressure pipe body, of the sealing plug.
4. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 3, characterized in that: the distance between the filter screen and the sealing plug is 8-12 mm; the aperture of the filter screen is 1.8-2.2 mm.
5. The sodium citrate anticoagulation tube with function of detecting micro-clot according to claim 4, characterized in that: the center of the filter screen is fixedly connected with one end of the sealing plug corresponding to the interior of the vacuum negative pressure pipe body through a connecting column; the connecting column is arranged in a zigzag manner.
6. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 5, characterized in that: and the inner wall of the opening end of the vacuum negative pressure pipe body is provided with a locking thread for fixing the sealing plug.
7. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 6, characterized in that: the protective cover is embedded outside the sealing plug and is in threaded connection with the outer wall of the opening end of the vacuum negative pressure pipe body; the protective cover is provided with a through hole corresponding to the groove.
8. The sodium citrate anticoagulation tube with function of detecting micro-clot as claimed in claim 3, characterized in that: the bottom of the groove is provided with a conical bulge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110145154.XA CN112932483A (en) | 2021-02-02 | 2021-02-02 | Sodium citrate anticoagulation tube with function of detecting micro-clots |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110145154.XA CN112932483A (en) | 2021-02-02 | 2021-02-02 | Sodium citrate anticoagulation tube with function of detecting micro-clots |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112932483A true CN112932483A (en) | 2021-06-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110145154.XA Pending CN112932483A (en) | 2021-02-02 | 2021-02-02 | Sodium citrate anticoagulation tube with function of detecting micro-clots |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112932483A (en) |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201414802Y (en) * | 2009-05-08 | 2010-03-03 | 刘辰庚 | Vacuum blood sampling tube |
| CN203677102U (en) * | 2013-11-25 | 2014-07-02 | 黑龙江农垦职业学院 | Vacuum blood collection tube |
| CN203852359U (en) * | 2014-04-23 | 2014-10-01 | 湖南千山制药机械股份有限公司 | Vacuum blood collection tube for separating plasma |
| CN106108920A (en) * | 2016-08-23 | 2016-11-16 | 郭小兵 | A kind of negative pressure leaching formula sampled plasma device being applicable to medical experiment |
| CN207613774U (en) * | 2017-02-09 | 2018-07-17 | 辽宁启福干细胞生物科技有限责任公司 | A kind of bag for collecting cord blood |
| CN207768401U (en) * | 2017-06-19 | 2018-08-28 | 河南省安邦卫材有限公司 | Disposable vacuum blood collection tube |
| CN207949809U (en) * | 2017-09-12 | 2018-10-12 | 北京旌准医疗科技有限公司 | A kind of vacuum blood collection tube |
| CN209153714U (en) * | 2018-07-25 | 2019-07-26 | 广西华度医用器材有限公司 | A kind of heparin tube of the oblique insertion of bootable syringe needle |
| CN111772646A (en) * | 2020-08-11 | 2020-10-16 | 无锡市第五人民医院 | Low sample volume sampler |
| CN211883812U (en) * | 2020-03-09 | 2020-11-10 | 成都市妇女儿童中心医院 | Vacuum blood collection tube |
-
2021
- 2021-02-02 CN CN202110145154.XA patent/CN112932483A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201414802Y (en) * | 2009-05-08 | 2010-03-03 | 刘辰庚 | Vacuum blood sampling tube |
| CN203677102U (en) * | 2013-11-25 | 2014-07-02 | 黑龙江农垦职业学院 | Vacuum blood collection tube |
| CN203852359U (en) * | 2014-04-23 | 2014-10-01 | 湖南千山制药机械股份有限公司 | Vacuum blood collection tube for separating plasma |
| CN106108920A (en) * | 2016-08-23 | 2016-11-16 | 郭小兵 | A kind of negative pressure leaching formula sampled plasma device being applicable to medical experiment |
| CN207613774U (en) * | 2017-02-09 | 2018-07-17 | 辽宁启福干细胞生物科技有限责任公司 | A kind of bag for collecting cord blood |
| CN207768401U (en) * | 2017-06-19 | 2018-08-28 | 河南省安邦卫材有限公司 | Disposable vacuum blood collection tube |
| CN207949809U (en) * | 2017-09-12 | 2018-10-12 | 北京旌准医疗科技有限公司 | A kind of vacuum blood collection tube |
| CN209153714U (en) * | 2018-07-25 | 2019-07-26 | 广西华度医用器材有限公司 | A kind of heparin tube of the oblique insertion of bootable syringe needle |
| CN211883812U (en) * | 2020-03-09 | 2020-11-10 | 成都市妇女儿童中心医院 | Vacuum blood collection tube |
| CN111772646A (en) * | 2020-08-11 | 2020-10-16 | 无锡市第五人民医院 | Low sample volume sampler |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210611 |
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| RJ01 | Rejection of invention patent application after publication |