CN112915370A

CN112915370A - Device for local administration of acute radiation esophagitis esophagus

Info

Publication number: CN112915370A
Application number: CN202110283042.0A
Authority: CN
Inventors: 赵汉玺; 贾丽; 邢力刚; 李晓琳; 牛学才; 朱婉琦
Original assignee: Cancer Hospital of Shandong First Medical University
Current assignee: Cancer Hospital of Shandong First Medical University
Priority date: 2021-03-16
Filing date: 2021-03-16
Publication date: 2021-06-08
Anticipated expiration: 2041-03-16
Also published as: CN112915370B

Abstract

The invention discloses a device for local administration of acute radiation esophagitis esophagus, and belongs to the technical field of medical instruments. The device comprises a capsule of which the rear end is connected with a pulling line, wherein the capsule comprises a shell and a micro-transmission mechanism fixed in the shell of the capsule. The micro-motor in the micro-transmission mechanism is electrically connected with the battery pack and the micro-controller, the micro-transmission mechanism comprises a rack unfolding and folding mechanism and a spiral extrusion mechanism, the spiral extrusion mechanism is used for extruding a medium in the main bag into the sub-bag, the rack unfolding and folding mechanism which is matched with the spiral extrusion mechanism to act pushes the sub-bag to stretch out of the shell, the main bag and the sub-bag are directly connected with a magnetic control valve, and the magnetic control valve is matched with the actions of the spiral extrusion mechanism and the rack unfolding and folding mechanism to be opened and closed. The device can increase the duration of the medicine acting on the local part of the esophagus, and is convenient, safe and reliable to use.

Description

Device for local administration of acute radiation esophagitis esophagus

The technical field is as follows:

the invention relates to the technical field of medical instruments, in particular to a device for local administration of acute radiation esophagitis esophagus.

Background art:

radiotherapy is one of the main means of tumor treatment, and can kill tumor cells effectively, but at the same time inevitably causes radioactive damage to normal tissues and organs around the tumor, and produces various complications and sequelae. Acute radiation esophagitis belongs to local radiotherapy complications and is frequently generated in breast tumor radiotherapy of lung cancer, esophageal cancer and the like. When the cumulative radiation dose of the esophagus reaches DT20Gy-40Gy mostly, the acute radiation esophagitis is aseptic inflammation generated by radiation injury of the esophageal mucosa, congestion and edema of the esophageal mucosa in a radiation field, superficial ulcer formation and erosive exudative change are caused by radiation damage to the normal esophageal mucosa, and clinical symptoms are aggravated by infection on the basis of the congestion and edema.

Acute radiation esophagitis not only affects the life quality of patients, but also directly affects the smooth operation of radiotherapy in severe cases, thereby prolonging the treatment course and reducing the treatment effect. Therefore, the prevention and treatment of acute radiation esophagitis has important clinical significance for malignant tumor radiotherapy.

At present, the main method for clinically treating acute radiation esophagitis is to slowly take oral liquid preparation to achieve the local treatment effect, such as orally taking esophagitis mixture with glucocorticoid and local anesthetic as main components and recovery new liquid with periplaneta americana extract as a main component. However, the drugs are not easy to stay on the surface of the esophageal mucosa or stay for too short time, and the treatment effect on the acute radiation esophagitis is limited.

The invention content is as follows:

in order to solve the problems, the invention aims to provide a device for local administration of acute radiation esophagitis in the esophagus, which can prolong the time of acting the medicine on the local part of the esophagus and is convenient, safe and reliable to use.

The technical scheme adopted by the invention for solving the technical problems is as follows:

a device for local administration of acute radiation esophagitis esophagus comprises a capsule, the rear end of which is connected with a pulling line; the capsule comprises a capsule shell and a micro-transmission mechanism fixed in the capsule shell, wherein a micro-motor in the micro-transmission mechanism is electrically connected with the battery pack and the micro-controller; the micro-transmission mechanism comprises a rack unfolding and folding mechanism and a spiral extrusion mechanism, wherein a rack of the rack unfolding and folding mechanism is connected with a sliding plate, the sliding plate is arranged on a base plate in a sliding manner, the base plate is fixed in a capsule shell, one end, close to the inner wall of the capsule shell, of the sliding plate is provided with a magnetic control valve, the magnetic control valve is connected with a main pipe and branch pipes, one end of the main pipe is connected to a hemispherical main bag, one end of each branch pipe is connected to an annular branch bag, the side surface of the capsule shell is provided with a notch for the annular branch bags to stretch, and media are filled in; the screw cap of the screw extrusion mechanism is connected with the extrusion plate on the extrusion frame, and the main bag is arranged in the extrusion frame.

As an improvement of the technical scheme of the invention, the rack folding and unfolding mechanism comprises a gear set and a rack set, two gears of the gear set are fixedly connected on a transmission shaft, the transmission shaft is connected with the output end of a micro motor, two racks of the rack set are respectively meshed with corresponding gears, the motion directions of the two racks are opposite, the two groups of sliding plates are arranged, the two racks are respectively and fixedly connected with corresponding sliding plates, a sliding groove is formed in the base plate, and the sliding plates and the sliding grooves form a sliding pair.

As a further improvement of the invention, a section of the transmission shaft close to the outer end is a screw rod, the screw cap is screwed with the screw rod, the end part of the transmission shaft is rotatably arranged on a shaft base, and the shaft base is fixed on the capsule shell.

As a further preferable mode of the present invention, the extrusion frame includes two groups of holding frames and two groups of extrusion plates, the holding frames are symmetrically arranged, the holding frames are fixed in the capsule shell, the holding frames are provided with arc-shaped grooves, the upper portion of the extrusion plate is sleeved with a movable plate, and the outer ends of the movable plate are rotatably connected with the arc-shaped grooves.

As a further preferable mode of the present invention, the outer side of the capsule is connected with a fitting pad, the fitting pad is fitted with the notch, a guide nozzle is further disposed in the capsule housing at a position corresponding to the notch, the cross section of the guide nozzle is bucket-shaped, one end of the guide nozzle is fixed on the capsule housing, the other end of the guide nozzle is provided with a pressure port, and a portion of the capsule passing through the guide nozzle is reduced and enters the housing.

As a further preferred of the present invention, the sub-bag comprises two independent chambers, a chamber close to the fit pad is a constant chamber, the constant chamber is sealed after being filled with a medium, and the other chamber is a variable chamber communicated with the sub-tube.

As a further preferred aspect of the present invention, a supporting layer is attached to the outer wall of the sub-bag connected to the attaching pad; the wall of the constant cavity in the sub-bag is provided with a filling port, and the attaching pad is provided with an avoiding port matched with the filling port.

As a further preferred aspect of the present invention, the magnetic control valve includes an electromagnet, a valve seat, and a valve element, the valve element is sleeved in the valve seat and fixed by a valve cover on the valve seat, the electromagnet is fixed on the valve seat and corresponds to the valve cover, the valve element includes a core cover, an exchange block, and a core body, the core cover is fixed on the core body, the exchange block is disposed between the core cover and the core body, the exchange block is provided with a pilot hole and a bypass hole, an internal groove of the core cover is provided with a dynamic pressure body, the dynamic pressure body includes a protective shell, a magnetic absorption block, a hole sealing plug, and a shell plug, the hole sealing plug positions the magnetic absorption block in the protective shell, the shell plug limits a part of the hole sealing plug in the protective shell, the other part of the hole sealing plug passes through the shell plug and abuts against the pilot hole; the core body is provided with two chambers which are respectively used for communicating the pilot hole and the bypass hole, the side surface of the core body is provided with a communicating hole which is used for connecting the branch pipe, the open end of the core body is used for connecting the communicating hole of the main pipe, the two communicating holes are respectively communicated with the corresponding chambers, and the valve seat is provided with a connecting port at the corresponding communicating hole.

As a further preferred aspect of the present invention, the medium is carbon dioxide gas.

As a further preferred feature of the present invention, the outer end of the pulling wire is sleeved with a sleeve, and the outer end of the sleeve is connected with a pulling ring.

Generally, compared with the prior art, the technical scheme of the invention mainly has the following advantages: the device is used for local administration of the esophagus in acute radiation esophagitis, can be accurately positioned at the local part of the esophagus, prolongs the action time of the medicine at the local part of the esophagus and improves the curative effect; the device of the invention adopts a swallowing mode to enter the body and a wire pulling mode to take out the body, does not need to enter or discharge the body through means such as operation, and has no harm in the process of intake and discharge; the device of the invention is in the form of capsule, has small size and reasonable mechanism design, can be safely eaten and is convenient to take and discharge; the device of the invention can be repeatedly used, reduces the use cost, obtains obvious curative effect by matching with the use of medicines, and is worthy of clinical popularization.

Description of the drawings:

FIG. 1 is a state diagram of an embodiment of the present invention.

Fig. 2 is a front sectional view of a collapsed state according to an embodiment of the present invention.

FIG. 3 is a front cut-away view of an expanded state of an embodiment of the present invention.

Fig. 4 is a right side view of the embodiment of the present invention in the unfolded state.

FIG. 5 is a schematic view of a capsule in an expanded state according to an embodiment of the present invention.

Fig. 6 is an enlarged view of a portion a in fig. 3.

Fig. 7 is a schematic structural diagram of an extrusion frame according to an embodiment of the present invention.

Fig. 8 is a partial structural schematic diagram of a micro-actuator according to an embodiment of the invention.

Fig. 9 is a sectional view of a magnetic control valve according to an embodiment of the present invention.

In the figure, 1, capsule, 2, lifting wire, 3, sleeve, 4, pull ring, 10, shell, 101, connecting frame, 102, guide nozzle, 103, notch, 11, battery pack, 12, micro-controller, 13, micro-motor, 141, gear 142, rack, 143, gear, 144, rack, 145, sliding plate, 146, sliding plate, 147, sliding groove, 148, base plate, 149, latex tape, 151, transmission shaft, 152, screw rod, 153, screw cap, 154, shaft base, 155, upright rod, 16, main capsule, 17, sub-capsule, 171, constant chamber, 172, variable chamber, 181, joint pad, 182, support layer, 183, filling port, 184, elastic membrane, 191, accommodating frame, 192, arc groove, 193, extrusion plate, 194, movable plate, 51, main tube, 52, sub-tube, 61, electromagnet, 62, valve seat, 63, 64, core cover, 65, exchange block, 651, pilot hole, 66. the core body, 661, intercommunicating pore, 662, intercommunicating pore, 671, protective case, 672, magnet attracting block, 673, hole sealing plug, 674, spring, 675, case plug.

The specific implementation mode is as follows:

because acute radiation esophagitis is mainly the damage of radiation to esophageal mucosa, congestion, edema, ulcer and erosion are caused, patients can have swallowing pain, esophageal burning sensation, pain after sternum and the like during eating, unnecessary physical and psychological burdens are added to the patients, the curative effect of radiotherapy is influenced, and even the tumor cells are accelerated to proliferate due to the forced interruption of the radiotherapy. The invention aims to relieve the pain of patients and improve the life quality of the patients. In order to clearly explain the technical features of the present invention, the following detailed description of the present invention is provided with reference to the accompanying drawings.

The device for local administration of the esophagus in the embodiment of the invention comprises a capsule 1, the rear end of the capsule 1 is connected with a pull-up wire 2, referring to fig. 1, a patient takes the capsule 1 and a part of the pull-up wire 2 with warm water until the outer part of the pull-up wire 2 has a specified length, and the outer part of the pull-up wire 2 can be wound by adhesive plaster and then pasted above the corner of the mouth of the patient. And later, the mixture liquid for treating the acute radiation esophagitis is taken. During this period, the patient may be doing normal minor activities, but not eating food. A sleeve 3 can be selectively sleeved at the outer end of the pulling-up wire 2, the outer end of the sleeve 3 is connected with a pulling ring 4, and the sleeve 3 is used for preventing the pulling-up wire 2 from rubbing mucous membrane of throat to cause local injury and uncomfortable feeling.

Referring to fig. 2 and 3, the capsule 1 includes a capsule housing 10, a micro-actuator fixed in the capsule housing 10, and a micro-motor 13 in the micro-actuator electrically connected to a battery 11 and a micro-controller 12. The battery pack 11 is used for supplying power to the micro controller 12 and the micro motor 13, the wireless transceiver on the micro controller 12 can receive the instruction signal of the external control device, and after receiving the instruction signal, the single chip microcomputer in the micro controller 12 can control the starting, stopping and rotating angle of the micro motor 13.

The micro-transmission mechanism comprises a rack unfolding and folding mechanism and a spiral extrusion mechanism, the rack unfolding and folding mechanism comprises a gear set and a rack set, two

gears

141 and 143 of the gear set are fixedly connected on a transmission shaft 151, and the

gears

141 and 143 are in interference fit with the transmission shaft 151 or are connected through keys as shown in fig. 6. The transmission shaft 151 is connected to the output end of the micro-motor 13, the two racks of the rack set are respectively engaged with the corresponding gears, i.e. the gear 141 is engaged with the rack 142, the gear 143 is engaged with the rack 144, the tooth surfaces of the two

racks

142, 144 are opposite, i.e. when the rack 144 is installed below the corresponding gear 143, the other rack 142 is installed above the corresponding gear 141, so as to ensure that the moving directions of the two

racks

142, 144 are opposite, the rack 142 is connected to the sliding plate 145, the rack 144 is connected to the sliding plate 146, wherein the rack 144 is directly fixed on the sliding plate 146, and the other rack 142 is connected to the sliding plate 145 through the upright rod 155, so that the two

racks

142, 144 are respectively located at two sides of the transmission shaft. The

sliding plates

145 and 146 are slidably disposed on a base plate 148, the base plate 148 is fixed in the capsule housing 10, a sliding slot 147 is formed in the base plate 148, and the

sliding plates

145 and 146 can move back and forth along the sliding slot 147 without departing from the sliding slot 147. The

sliding plates

145 and 146 are provided with magnetic control valves at one ends close to the inner wall of the capsule shell 10, the magnetic control valves are connected with a main tube 51 and branch tubes 52, one end of the main tube 51 is connected to the hemispherical main bag 16, one end of the branch tubes 52 is connected to the annular branch bags 17, the side face of the capsule shell 10 is provided with a notch 103 for the annular branch bags 17 to extend, the main tube 51 is a corrugated soft tube, and the branch tubes 52 are hard tubes. Referring to fig. 8, since the capsule housing 10 is provided with the notch 103, the capsule housing 10 is divided into two parts by the notch 103 and connected integrally by the connecting frame 101 in the housing 10.

The section of the transmission shaft 151 near the outer end is a screw rod 152, a screw cap 153 of the screw extrusion mechanism is connected with an extrusion plate 192 on the extrusion frame 19, the main bladder 16 is arranged in the extrusion frame 19, the screw cap 153 is screwed with the screw rod 152, the end part of the transmission shaft 151 is rotatably arranged on a shaft base 154, and the shaft base 154 is fixed on the bladder shell 10. Referring to fig. 7, the pressing frame 19 includes an accommodating frame 191 and a pressing plate 193, the accommodating frame 191 is symmetrically arranged into two groups, the accommodating frame 191 is fixed in the capsule shell 10, an arc-shaped groove 192 is formed in the accommodating frame 191, a movable plate 194 is sleeved on the upper portion of the pressing plate 193, the outer end of the movable plate 194 is rotatably connected with the arc-shaped groove 192 through a rotating shaft, the movable plate 194 can move along the arc-shaped groove 192 and stretch along the pressing plate 193, and the outer end of the movable plate 194 and the arc-shaped groove 192 form a sliding pair.

Both the main bag 16 and the sub-bags 17 are filled with a medium, preferably carbon dioxide gas harmless to human body. The outer side of the sub-capsule 17 is connected with a bonding pad 181, the bonding pad 181 is matched with a notch 103, a guide nozzle 102 is further arranged at a position corresponding to the notch 103 in the capsule shell 10, the cross section of the guide nozzle 102 is bucket-shaped, one end of the guide nozzle 102 is fixed on the capsule shell 10, the other end of the guide nozzle 102 is provided with a pressure port, the part of the sub-capsule 17 passing through the guide nozzle 102 is reduced and then enters the shell 10, and in order to prevent liquid medicine from entering the capsule, the inner side of the guide nozzle 102 can be covered with a water absorption cushion layer. Referring to fig. 4, four pads 181 are provided, and the four pads 181 can be folded to fit the notches 103 to close the notches 103 on the capsule housing 10. Two adjacent fit pads 181 are connected by an elastic membrane 184. The sac 17 comprises two independent chambers, wherein a chamber close to the attaching pad 181 is a constant chamber 171, the constant chamber 171 is sealed after being filled with a medium, and the other chamber is a variable chamber 172 communicated with the branch pipe 52. A supporting layer 182 is attached to the outer wall of the sub-bag 17 connected with the attaching pad 181, and the supporting layer 182 thickens and reinforces the outer wall of the sub-bag 17 and is more closely fused with the attaching pad 181; the wall of the constant chamber 171 of the sub-bag 17 is provided with a filling port 183, and the joint pad 181 is provided with an avoiding port matched with the filling port 183. To better ensure the retraction of the sub-bag 17, the outer wall of the inner ring of the sub-bag 17 is connected with an emulsion tape 149, and referring to fig. 5 and fig. 1 and 2, four emulsion tapes 149 are respectively fixed on the side surfaces of the base plate 148.

Referring to fig. 9, the magnetic control valve includes an electromagnet 61, a valve seat 62 and a valve core, the valve core is sleeved in the valve seat 62 and fixed by a valve cover 63 on the valve seat 62, the electromagnet 61 is fixed on the valve seat 62 and corresponds to the position of the valve cover 63, the valve core includes a core cover 64, an exchange block 65 and a core body 66, the core cover 64 is fixed on the core body 66, the exchange block 65 is arranged between the core cover 64 and the core body 66, a pilot hole 651 and a bypass hole 652 are arranged on the exchange block 65, a dynamic pressure body is arranged in an inner groove of the core cover 64, the dynamic pressure body includes a protective shell 671, a magnetic suction block 672, a hole sealing plug 673 and a shell plug 675, the hole sealing plug 673 positions the magnetic suction block 672 in the protective shell 671, the shell plug 675 limits a part of the hole sealing plug 673 in the protective shell 671, another part of the hole sealing plug 673 is abutted to the pilot hole 651 through the shell plug 675; the core 66 is provided with two chambers for communicating the pilot hole 652 and the bypass hole 652 with each other, the chamber communicating with the pilot hole 652 is a pilot chamber, the chamber communicating with the bypass hole 652 is a bypass chamber, a communication hole 661 for connecting the branch pipe 52 is provided on a side surface of the core 66, an opening end of the core 66 is provided for connecting the communication hole 662 of the main pipe 51, the two

communication holes

661, 662 are respectively communicated with the corresponding chambers, and a connection port is provided on the valve seat 62 at the

corresponding communication holes

661, 662.

The working mode of the whole device is as follows:

the capsule 1 and a part of the pulling wire 2 enter the esophagus of a human body in a normal oral way, the pulling wire 2 enters the body to a reserved length, namely the capsule 1 reaches a designated esophagus section, and the device keeps the initial state, namely the variable cavity 172 of the annular capsule 17 is partially retracted into the capsule shell 10, namely the whole capsule 1 is in a closed state. The normal esophageal dilatation diameter is usually two to three centimeters, and the esophageal diameter of the segment can be estimated in advance so as to accurately control the actions of the micromotor 13 and the magnetic control valve. As mentioned above, in order to prevent the local injury and discomfort caused by the friction of the throat mucous membrane of the pulling wire 2, the sleeve 3 is sleeved outside the outer end of the pulling wire 2, the outer end of the sleeve 3 is connected with the pulling ring 4 to facilitate the pulling, one part of the sleeve 3 is contained in the mouth of a patient, teeth do not bite the sleeve 3 as much as possible to prevent the sleeve 3 from being damaged, and the outer end of the pulling wire 2 can still be fixed at the mouth corner of the patient through the adhesive plaster. After the external control device sends out a signal, the micro-controller 12 of the internal capsule 1 receives and processes the signal and controls the micro-motor 13 and the magnetic control valve, the output end of the micro-motor 13 transmits power to the transmission shaft 151, the

gears

141 and 143 rotate along with the transmission shaft 151, the two

racks

142 and 144 move in a back-to-back manner, the screw cap 153 moves along the screw rod 152, the screw cap 153 pushes the extrusion plate 193 of the extrusion frame to move, and the extrusion plate 193 extrudes the main capsule 16 to enable the gas medium in the main capsule 16 to enter the magnetic control valve. The electromagnet 61 of the magnetic control valve is a suction cup type electromagnet, after the electromagnet 61 is electrified, the electromagnet 61 can generate suction force on the magnetic suction block 672 of the dynamic pressure body of the core cover 64, and the shell plug 675 limits the magnetic suction block 672 and the hole sealing plug 673 in the protective shell 671, so the hole sealing plug 673 moves along with the magnetic suction block 672, and the hole sealing plug 673 leaves the pilot hole 651, namely the pilot hole 651 is opened. The gas medium enters the pilot chamber of the magnetic control valve through the main pipe 51, enters the bypass hole 652 and the bypass chamber through the pilot chamber and the pilot hole 651, and finally enters the variable cavity chamber 172 of the sub-bag 17 through the sub-pipe 52. The capsules 17 are slowly unfolded, the sliding

plates

145 and 146 move along the base plate 148 along with the movement of the

racks

142 and 144, and the magnetic control valve drives the branch pipes 52 and the capsules 17 to slowly extend out of the capsule shell 10 along with the sliding

plates

145 and 146. The variable cavity 172 slowly passes through the guide nozzle 102, the gas medium slowly enters the variable cavity 172 of the sub-capsule 17, and the action is kept until the micro-controller 12 controls the micro-motor 13 to stop rotating and the electromagnet 61 of the magnetic control valve is powered off, and at the moment, the joint pad 181 outside the constant cavity 171 of the sub-capsule 17 is jointed or is jointed to the wall of the esophagus. The liquid medicine is slowly drunk, the liquid medicine is retained by the sub-capsule 17 extending out of the capsule, the liquid medicine is generally sticky and is difficult to enter the capsule 1 because the sub-capsule 17 is supported at the notch 103 of the capsule 1. The liquid medicine is uniformly distributed along the periphery of the capsule 1 and above the sub-capsule 17, can stay at the local part of the esophagus for a long time, so that the medicine can play higher repairing, pain relieving and anti-inflammatory effects at the local part, effectively shorten the curing period, relieve the pain of a patient, prevent the interruption of radiotherapy and improve the survival rate.

After the electromagnet 61 is powered off, the dynamic pressure body is reset under the action of the spring 674, and the hole sealing plug 673 is pressed on the pilot hole 651 again, so that the communication between the pilot chamber and the bypass chamber is disconnected. After taking medicine for about 2-3 minutes, the external control device is controlled to send out a signal, the micro-controller 12 receives the signal and processes the signal to control the micro-motor 13 to reversely rotate, the pilot chamber and the bypass chamber of the magnetic control valve are communicated again, the screw cap 153 pulls the extrusion plate 193 to reversely move, the pressure in the main capsule 16 is reduced, the

racks

142 and 144 respectively drive the sliding

plates

145 and 146 and the magnetic control valve to reversely move, the variable chamber 172 part of the sub-capsule 17 is extruded by the guide nozzle 102, the gas in the variable chamber 172 enters the main capsule 16 from the main pipe 51 through the magnetic control valve, the constant chamber 171 of the sub-capsule 17 is retracted to the capsule shell 10, the attaching pad 181 is attached to the capsule shell 10 to seal the gap 103 on the capsule 1, and the liquid medicine enters the stomach through the esophagus. The patient should stop slightly to relax his mind and then pull the pulling wire 2 slowly when he or she feels resistance or nausea. If the sleeve 3 is arranged, the sleeve 3 can be inserted into a part of the esophagus along the lifting line and then lifted, so that the throat part can be effectively protected, and the lifting is faster.

The above-described embodiments should not be construed as limiting the scope of the invention, and any alternative modifications or alterations to the embodiments of the present invention will be apparent to those skilled in the art. The present invention is not described in detail, but is known to those skilled in the art.

Claims

1. A device for local administration of acute radiation esophagitis to the esophagus comprising: comprises a capsule, the rear end of the capsule is connected with a pulling line; the capsule comprises a capsule shell and a micro-transmission mechanism fixed in the capsule shell, wherein a micro-motor in the micro-transmission mechanism is electrically connected with the battery pack and the micro-controller; the micro-transmission mechanism comprises a rack unfolding and folding mechanism and a spiral extrusion mechanism, wherein a rack of the rack unfolding and folding mechanism is connected with a sliding plate, the sliding plate is arranged on a base plate in a sliding manner, the base plate is fixed in a capsule shell, one end, close to the inner wall of the capsule shell, of the sliding plate is provided with a magnetic control valve, the magnetic control valve is connected with a main pipe and branch pipes, one end of the main pipe is connected to a hemispherical main bag, one end of each branch pipe is connected to an annular branch bag, the side surface of the capsule shell is provided with a notch for the annular branch bags to stretch, and media are filled in; the screw cap of the screw extrusion mechanism is connected with the extrusion plate on the extrusion frame, and the main bag is arranged in the extrusion frame.

2. The device for the local esophageal administration of acute radiation esophagitis according to claim 1 wherein: the rack folding and unfolding mechanism comprises a gear set and a rack set, two gears of the gear set are fixedly connected to a transmission shaft, the transmission shaft is connected with the output end of a micro motor, two racks of the rack set are respectively meshed with corresponding gears, the motion directions of the two racks are opposite, the sliding plate is provided with two sets of racks, the two racks are fixedly connected with corresponding sliding plates respectively, a sliding groove is formed in the base plate, and the sliding plate and the sliding groove form a sliding pair.

3. The device for the local esophageal administration of acute radiation esophagitis according to claim 2 wherein: one section of the transmission shaft close to the outer end is a screw rod, the screw cap is connected with the screw rod in a rotating mode, the end portion of the transmission shaft is arranged on a shaft base in a rotating mode, and the shaft base is fixed on the capsule shell.

4. The device for the local esophageal administration of acute radiation esophagitis according to claim 3 wherein: the extrusion frame is including holding frame and stripper plate, it sets up to two sets of to hold the frame symmetry, holds the frame and fixes in the capsule shell, holds and has seted up the arc wall on the frame, the upper portion cover of stripper plate is equipped with the fly leaf, and the outer end and the arc wall of fly leaf rotate to be connected.

5. The device for the local esophageal administration of acute radiation esophagitis according to claim 4 wherein: the outer side of the capsule is connected with a fitting pad, the fitting pad is matched with the notch, a guide nozzle is further arranged at the position corresponding to the notch in the capsule shell, the cross section of the guide nozzle is bucket-shaped, one end of the guide nozzle is fixed on the capsule shell, a pressure port is formed in the other end of the guide nozzle, and the part of the capsule passing through the guide nozzle is reduced and then enters the shell.

6. The device for the local esophageal administration of acute radiation esophagitis according to claim 5 wherein: the sub-bag comprises two independent chambers, a chamber close to the attaching pad is a constant chamber, the constant chamber is sealed after being filled with a medium, and the other chamber is a variable chamber communicated with the sub-pipe.

7. The device for the local esophageal administration of acute radiation esophagitis according to claim 6 wherein: a supporting layer is attached to the outer wall of the sub-bag connected with the attaching pad; the wall of the constant cavity in the sub-bag is provided with a filling port, and the attaching pad is provided with an avoiding port matched with the filling port.

8. The device for the local esophageal administration of acute radiation esophagitis according to claim 7 wherein: the magnetic control valve comprises an electromagnet, a valve seat and a valve core, wherein the valve core is sleeved in the valve seat and fixed through a valve cover on the valve seat, the electromagnet is fixed on the valve seat and corresponds to the position of the valve cover, the valve core comprises a core cover, an exchange block and a core body, the core cover is fixed on the core body, the exchange block is arranged between the core cover and the core body, a pilot hole and a bypass hole are formed in the exchange block, a dynamic pressure body is arranged in an inner groove of the core cover, the dynamic pressure body comprises a protective shell, a magnetic absorption block, a hole sealing plug and a shell plug, the magnetic absorption block is positioned in the protective shell through the hole sealing plug, one part of the hole sealing plug is limited in the protective shell, the other part of the hole sealing plug penetrates through the shell plug and is abutted against the pilot; the core body is provided with two chambers which are respectively used for communicating the pilot hole and the bypass hole, the side surface of the core body is provided with a communicating hole which is used for connecting the branch pipe, the open end of the core body is used for connecting the communicating hole of the main pipe, the two communicating holes are respectively communicated with the corresponding chambers, and the valve seat is provided with a connecting port at the corresponding communicating hole.

9. The device for the local esophageal administration of acute radiation esophagitis according to claim 1 or 5, characterized in that: the medium is carbon dioxide gas.

10. The device for the local esophageal administration of acute radiation esophagitis according to claim 1 wherein: the outer end of the lifting wire is sleeved with a sleeve, and the outer end of the sleeve is connected with a pull ring.