CN112912111A - 用于视网膜神经节细胞中特异表达基因的启动子SynP17(ProB1) - Google Patents
用于视网膜神经节细胞中特异表达基因的启动子SynP17(ProB1) Download PDFInfo
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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| EP18202519.7 | 2018-10-25 | ||
| EP18202519 | 2018-10-25 | ||
| PCT/IB2019/059088 WO2020084537A1 (en) | 2018-10-25 | 2019-10-24 | Synp17 (prob1), a promoter for the specific expression of genes in retinal ganglion cells |
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| CN112912111A true CN112912111A (zh) | 2021-06-04 |
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| EP (1) | EP3870238A1 (https=) |
| JP (1) | JP2022505516A (https=) |
| CN (1) | CN112912111A (https=) |
| WO (1) | WO2020084537A1 (https=) |
Cited By (1)
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| CN120290554A (zh) * | 2024-09-10 | 2025-07-11 | 广州市未来基因递送研究院 | 感光细胞特异性双向启动子及其用途 |
Families Citing this family (12)
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| MX2010011467A (es) | 2008-04-18 | 2011-02-15 | Novartis Forschungsstiftung | Novedosas herramientas y metodos terapeuticos para tratar la ceguera. |
| US10941417B2 (en) | 2015-04-30 | 2021-03-09 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in Müller cells |
| US10857241B2 (en) | 2015-09-15 | 2020-12-08 | Friedrich Miescher Institute For Biomedical Research | Therapeutical tools and methods for treating blindness by targeting photoreceptors |
| WO2017064642A1 (en) | 2015-10-14 | 2017-04-20 | Fredrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in retinal endothelial cells |
| EP3383440B1 (en) | 2015-12-03 | 2021-06-30 | Friedrich Miescher Institute for Biomedical Research | Synp162, a promoter for the specific expression of genes in rod photoreceptors |
| EP3383439B1 (en) | 2015-12-03 | 2019-09-25 | Friedrich Miescher Institute for Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| WO2017093934A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp160, a promoter for the specific expression of genes in rod photoreceptors |
| ES2909444T3 (es) | 2015-12-03 | 2022-05-06 | Friedrich Miescher Institute For Biomedical Res | Synp159, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| RU2766353C2 (ru) | 2016-11-02 | 2022-03-15 | Фридрих Мишер Инститьют Фор Байомедикал Рисерч | Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления |
| WO2018146588A1 (en) | 2017-02-08 | 2018-08-16 | Friedrich Miescher Institute For Biomedical Research | Synp88, a promoter for the specific expression of genes in retinal ganglion cells |
| MX2020005033A (es) | 2017-11-15 | 2020-10-28 | Friedrich Miescher Institute For Biomedical Res | Promotor especifico de las celulas del epitelio pigmentario retinal en primates. |
| SG11202005024QA (en) | 2017-11-30 | 2020-06-29 | Friedrich Miescher Institute For Biomedical Res | Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium |
Citations (1)
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| CN108474001A (zh) * | 2015-12-03 | 2018-08-31 | 弗里德里克·米谢尔生物医学研究所 | SynP160，用于基因在视杆光感受器中特异性表达的启动子 |
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| KR101342522B1 (ko) * | 2011-02-22 | 2013-12-17 | 숙명여자대학교산학협력단 | ＥｐｈＡ7 유전자의 인핸서 인자 및 그것의 용도 |
| EP3176177A1 (en) * | 2015-12-03 | 2017-06-07 | Friedrich Miescher Institute for Biomedical Research | Synp157, a promoter for the specific expression of genes in rod photoreceptors |
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2019
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- 2019-10-24 EP EP19794699.9A patent/EP3870238A1/en active Pending
- 2019-10-24 JP JP2021521788A patent/JP2022505516A/ja not_active Withdrawn
- 2019-10-24 CN CN201980069409.XA patent/CN112912111A/zh active Pending
- 2019-10-24 US US17/287,375 patent/US20210395750A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108474001A (zh) * | 2015-12-03 | 2018-08-31 | 弗里德里克·米谢尔生物医学研究所 | SynP160，用于基因在视杆光感受器中特异性表达的启动子 |
Non-Patent Citations (2)
| Title |
|---|
| JOSEPHINE JÜTTNER等: "Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates, and humans", NATURE NEUROSCIENCE, pages 1 - 73 * |
| SANDRA SIEGERT等: "Transcriptional code and disease map for adult retinal cell types", NATURE NEUROSCIENCE, vol. 15, no. 3, pages 487 - 497 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120290554A (zh) * | 2024-09-10 | 2025-07-11 | 广州市未来基因递送研究院 | 感光细胞特异性双向启动子及其用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3870238A1 (en) | 2021-09-01 |
| JP2022505516A (ja) | 2022-01-14 |
| US20210395750A1 (en) | 2021-12-23 |
| WO2020084537A1 (en) | 2020-04-30 |
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